Relevant bibliographies by topics / Sulfonamide Derivatives

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Sulfonamide Derivatives'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Sulfonamide Derivatives"

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Baraa G. Alani, Khulood S Salim, Alaa Saleh Mahdi, and Ahmed Alaa Al-Temimi. "Sulfonamide derivatives: Synthesis and applications." International Journal of Frontiers in Chemistry and Pharmacy Research 4, no. 1 (2024): 001–5. http://dx.doi.org/10.53294/ijfcpr.2024.4.1.0021.

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Sulfonamides belong to an important class of compounds which showed wide ranges of biological activities like antibacterial, antiviral, diuretic, hypo-glycemic, anticancer, anti-inflammatory and recently anti-covid-19. Over the last few decades, various pharmacological activities of sulfonamide conjugates were published. Moreover, many lead compounds with sulfonamide functionality are also in clinical trial for the treatment of various medical conditions. For these reasons, development of an efficient process for the synthesis of sulfonamides has always been in the focus for research in organi
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Sadawarte, Gautam, Samadhan Jagatap, Mukesh Patil, Vasant Jagrut, and Jamatsing Darbarsing Rajput. "Synthesis of substituted pyridine based sulphonamides as an antidiabetic agent." European Journal of Chemistry 12, no. 3 (2021): 279–83. http://dx.doi.org/10.5155/eurjchem.12.3.279-283.2118.

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This research work describes the synthesis of a new series of heterocyclic compounds, namely sulfonamide derivatives. Sulfonamides are a diverse class of organic compounds having significant and potent biological activities. Diverse synthetic methods have been engaged to build up its various derivatives for different biological functions. In this study, the production of novel pyridine-based heterocyclic compounds having sulfonamide moieties has been elaborated. The obtained sulfonamide-based pyridine scaffold was used to investigate their alpha-amylase inhibition activity. The structures of f
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Hossan, Aisha SM. "Synthesis of new thiophene dyes clubbed with sulfonamide for the creation of antibacterial polyester fabrics." Textile Research Journal 90, no. 3-4 (2019): 376–85. http://dx.doi.org/10.1177/0040517519868176.

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The current study targets to synthesize some new sulfonamido-hydroxythiophene dyes for dyeing polyester fabrics with estimated antibacterial activity. The structure of sulfonamide dyes was adapted by conducting with sulfadimidine and sulfamethaxole through the coupling reaction. The synthesized derivatives were established by spectroscopic tools (Fourier transform infrared spectroscopy, proton nuclear magnetic resonance). Hydroxy-thiophene-containing sulfonamides were utilized for dyeing polyester fabric. The prepared sulfonamido-hydroxythiophene dyes were applied on polyester fabrics after es
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Irfan, Ali, Laila Rubab, Mishbah Ur Rehman, et al. "Coumarin sulfonamide derivatives: An emerging class of therapeutic agents." Heterocyclic Communications 26, no. 1 (2020): 46–59. http://dx.doi.org/10.1515/hc-2020-0008.

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AbstractCoumarin sulfonamide is a heterocyclic pharmacophore and an important structural motif which is a core and integral part of different therapeutic scaffolds and analogues. Coumarin sulfonamides are privileged and pivotal templates which have a broad spectrum of applications in the fields of medicine, pharmacology and pharmaceutics. Coumarin sulfonamide exhibited versatile and myriad biomedical activities such as anti-bacterial, antiviral, antifungal, anti-inflammatory and anti-cancer. This review article focuses on the structural features of coumarin sulfonamide derivatives in the treat
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Supuran, Claudiu T. "Thienothiopyransulfonamides as Complexing Agents for the Preparation of Dual Carbonic Anhydrase Inhibitors." Metal-Based Drugs 2, no. 6 (1995): 327–30. http://dx.doi.org/10.1155/mbd.1995.327.

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Co(II); Zn(II) and Cu(II) complexes of two new sulfonamide carbonic anhydrase (CA) inhibitors, derivatives of thienothiopyran-2-sulfonamide, were prepared and characterized by analytic, spectroscopic, magnetic and conductimetric measurements. The new complexes are more potent CA inhibitors than the parent sulfonamides, with IC50 values around 0.1 nM, against isozyme CA II.
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Moskalik, Mikhail Yu, Vera V. Astakhova, and Bagrat A. Shainyan. "Oxidative sulfamidation as a route to N-heterocycles and unsaturated sulfonamides." Pure and Applied Chemistry 92, no. 1 (2020): 123–49. http://dx.doi.org/10.1515/pac-2018-1219.

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AbstractOxidative sulfamidation is a promising approach to the synthesis of numerous organic compounds, including N-heterocycles or unsaturated species having the sulfonamide group, which is a key structural motif of synthetic antimicrobial drugs. The formed products can undergo further reactions leading to a wide variety of functionalized sulfonamides. This review summarizes the current state of knowledge on the oxidative reactions of sulfonamides and their derivatives with unsaturated and CH-active compounds with an emphasis on dienes as substrates. This produces a diverse range of compounds
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Pastewska, Monika, Beata Żołnowska, Strahinja Kovačević, et al. "Modeling of Anticancer Sulfonamide Derivatives Lipophilicity by Chemometric and Quantitative Structure-Retention Relationships Approaches." Molecules 27, no. 13 (2022): 3965. http://dx.doi.org/10.3390/molecules27133965.

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Sulfonamides are a classic group of chemotherapeutic drugs with a broad spectrum of pharmacological action, including anticancer activity. In this work, reversed-phase high-performance liquid chromatography and biomimetic chromatography were applied to characterize the lipophilicity of sulfonamide derivatives with proven anticancer activities against human colon cancer. Chromatographically determined lipophilicity parameters were compared with obtained logP, employing various computational approaches. Similarities and dissimilarities between experimental and computational logP were studied usi
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Kamal, Mehnaz. "Synthesis, in silico toxicity prediction, and in vitro antibacterial activity of new 4-amino-N-arylbenzenesulfonamide derivatives." INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY 35, no. 01 (2025): 63. https://doi.org/10.59467/ijhc.2025.35.63.

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A significant class of compounds with a variety of biological applications is sulfonamides. The present work deals with the synthesis of 4-amino-N-arylbenzenesulfonamide derivatives (1-8) by the reaction of acetanilide-4- sulfonyl chloride and 4-substituted arylamine followed by hydrolysis to deprotect the acetyl group and give free amino group. Using disc diffusion, the synthesized derivatives were tested for in vitro antibacterial activities against Pseudomonas aeruginosa and Staphylococcus aureus. Ampicillin was used as a reference standard drug. Prediction of chemical toxicity was determin
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Varani, Tania, Majid Abdouss, Parisa Azerang, and Azar Tahghighi. "Acetylenic Sulfones and Acetylenic Sulfonamide Analogs: A Novel and Preferable Antimicrobial Drugs Based on Computational Strategies." Journal of Computational Biophysics and Chemistry 21, no. 01 (2021): 115–22. http://dx.doi.org/10.1142/s2737416521410027.

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This study was done to report virtual screening and molecular docking studies of sulfacetamide derivatives as new antimicrobial drugs, belonging to the pharmacological class of sulfonamides. For this purpose, sulfonamide functional groups from a library of chemical structures were converted into acetylenic sulfone and acetylenic sulfonamide functional groups to introduce a new class of antimicrobial drugs with mechanisms of action of dihydropteroate synthase inhibitors (DHPS). Initially, a library of compounds containing approximately 170 acetylenic sulfone ligands was created by similarity se
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Azevedo-Barbosa, Helloana, Danielle Ferreira Dias, Lucas Lopardi Franco, Jamie Anthony Hawkes, and Diogo Teixeira Carvalho. "From Antibacterial to Antitumour Agents: A Brief Review on The Chemical and Medicinal Aspects of Sulfonamides." Mini-Reviews in Medicinal Chemistry 20, no. 19 (2020): 2052–66. http://dx.doi.org/10.2174/1389557520666200905125738.

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Sulfonamides have been in clinical use for many years, and the development of bioactive substances containing the sulfonamide subunit has grown steadily in view of their important biological properties such as antibacterial, antifungal, antiparasitic, antioxidant, and antitumour properties. This review addresses the medicinal chemistry aspects of sulfonamides; covering their discovery, the structure- activity relationship and the mechanism of action of the antibacterial sulfonamide class, as well as the physico-chemical and pharmacological properties associated with this class. It also provide
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Dissertations / Theses on the topic "Sulfonamide Derivatives"

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Zhou, Yuan. "Synthetic studies towards homotyrosinol sulfonamide derivatives via Heck-Mizoroki coupling reactions." Thesis, University of British Columbia, 2009. http://hdl.handle.net/2429/16838.

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Homotyrosine, as a nonproteinogenic α-amino acid, is present as a component of diverse natural products that have important biological activities. Therefore, homotyrosine and its derivatives are important precursors for the total synthesis of some natural products. However, up to now, there was no report concerning a reliable synthetic route towards the synthesis of homotyrosine or its derivatives in a preparative scale. In this thesis, a robust method was developed for the preparation of homotyrosinol derivatives and related intermediates through a Mizoroki-Heck coupling reaction between an
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Bobba, Viharika. "SULFONAMIDE DERIVATIVES AS TUBULIN INHIBITORS AND SELECTIVE ANTI-TRYPANOSOME AGENTS – DESIGN, SYNTHESIS & BIOLOGICAL EVALUATION." Cleveland State University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=csu1468241198.

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Matak, Andrija. "Synthesis and spectroscopic analysis of 4'-amino and 4'-sulfonamide chalcone derivatives and ultrastructural effects of 4'-sulfonamide boronic acid chalcone on Eimeria papillata sporozoites in vitro /." Link to Theses, 2008. http://eprint.cc.andrews.edu/38/.

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Pan, Fangfang [Verfasser]. "Crystal Engineering and Charge Density Studies on Pharmaceutically Active Derivatives of Sulfonamides / Fangfang Pan." Aachen : Shaker, 2013. http://d-nb.info/1050344375/34.

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Couture, Karine. "Etude de la métallation en série diazinique 1) premier échange iode-lithium avec les alkylamidures de lithium 2) amination électrophile 3) première métallation sans groupe directeur." Rouen, 1995. http://www.theses.fr/1995ROUES020.

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Ce travail consiste en l'étude de la réaction de métallation en série diazinique. Dans une première partie, nous avons pu mettre en évidence pour la première fois en série diazinique, un mécanisme d'halogen-dance avec migration de l'iode. De plus, nous avons pu observer pour la première fois dans cette série, un exceptionnel échange iode-métal avec les alkylamidures de lithium. Cette réaction a été appliquée à la synthèse de leshmaniacides. Dans une seconde partie, nous avons mis au point l'amination électrophile par métallation en série diazinique. Cette réaction d'amination a été appliquée à
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林康媺. "Synthesis and bioactivity of novel sulfonamide derivatives." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/20477292656003492864.

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碩士<br>國防醫學院<br>藥學研究所<br>83<br>In the thesis, we conjugated five kinds of amines and various of sulfonyl chloride by sulfonaton. Thirty new products were successfully prepared in these experiments. All the target compounds comprise a sulfonamido functionality which might posses potential antihypertension and antiplatelet activities. All the end products prepared were tested, in vivo, for antiaggregation with rabbit blood. Blood from the tails of ICR mice was used to test the bleeding time
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Hung, Li-Tai, and 洪立泰. "Development of Gold Nanoparticles Capped with Benzene Sulfonamide Derivatives to Label and Purify Bovine Carbonic Anhydrase II Towards the Application in Proteomics." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/22770177203173773578.

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碩士<br>國立臺灣大學<br>化學研究所<br>93<br>The completion of Human Genome Project heralded the beginning of the proteome era. We are urged to develop new technology which shows the potential toward proteomics. By introducing the frontier nano- technology, traditional inhibitor design of targeting enzyme has provided a novel platform for facilitating labeling and purification of protein with high biocomplexity. Benzene Sulfonamide, a general type of carbonic anhydrase inhibitor combined with both a reactive epoxy group for affinity enhancement on labeling proteins and a thiol tail for anchoring on the gol
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Book chapters on the topic "Sulfonamide Derivatives"

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Westerduin, Peter, and Constant A. A. van Boeckel. "Synthesis of Newmyo-Inositol Derivatives Containing Phosphate, Sulfate, and Sulfonamido Groups." In ACS Symposium Series. American Chemical Society, 1991. http://dx.doi.org/10.1021/bk-1991-0463.ch008.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of linear mixed μ-acetato, μ-hydroxo bridged trinuclear copper(II) complex with N-sulfonamide derivative." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 7. Springer Berlin Heidelberg, 2023. http://dx.doi.org/10.1007/978-3-662-65895-6_460.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of linear mixed μ-acetato, μ-hydroxo bridged trinuclear copper(II) complex with N-sulfonamide derivative." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 7. Springer Berlin Heidelberg, 2023. http://dx.doi.org/10.1007/978-3-662-65895-6_461.

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Sanche, Stephen E., and Allan R. Ronald. "Sulfonamides and Trimethoprim." In Clinical Infectious Diseases. Oxford University PressNew York, NY, 1998. http://dx.doi.org/10.1093/oso/9780195081039.003.0035.

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Abstract Sulfonamide antibiotics are derivatives of sulfanilamide, the metabolite of a compound called prontosil that was developed by the German dye industry. Prontosil was reported to have antibacterial properties in 1932, and later in the same decade, sulfonamides were among the first antimicrobial agents to be used to treat infections in humans. Several synthetic derivatives with enhanced antimicrobial activity, improved pharmacokinetics, and more favorable side-effect profiles have subsequently been developed, allowing sulfonamides to maintain clinical usefulness six decades after the ini
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Kausar, Samia, Ataf Ali Altaf, Muhammad Hamayun, Amin Badshah, and Abdul Razzaq. "Supramolecular Chemistry and DNA Interaction Studies of Ferrocenyl Ureas and Thioureas." In Photophysics, Photochemical and Substitution Reactions- Recent Advances [Working Title]. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.84412.

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In this chapter, we have discussed the characteristics and bioapplicabilities of different ferrocene derivatives, for example, amides, amines, sulfonamide, and polymers, focusing mainly on urea and thiourea derivatives due to their autonomous and widespread spectroscopic action and bioactivities. Supramolecular chemistry of ferrocenyl ureas and thioureas is described owing to exploring their mode of interactions within and among the molecules and the role of these supramolecular structures in enhancing the DNA intercalation. DNA interaction studies of these ferrocenyl-based ureas and thioureas
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Taber, Douglass. "Substituted Benzenes: The Alvarez-Manzaneda Synthesis of (-)-Taiwaniquinone G." In Organic Synthesis. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780199764549.003.0065.

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Continuing efforts toward the direct functionalization of aromatic C-H bonds, Nobutaka Fujii and Hiroaki Ohno of Kyoto University described (Chem. Commun. 2009, 3413) a Pd-mediated protocol for the ortho hydroxylation of aryl tetrahydropyrimidines such as 1. To use a boronic acid as an activating/directing group, Michinori Suginome, also of Kyoto University, devised (J. Am. Chem. Soc. 2009, 131, 7502) the pyrazolylpyridyl derivative 3. The product 4 could be returned to the boronic acid or carried on to the borate ester, in each case with recovery of the directing group. Eiichi Nakamura of the
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Lambert, Tristan H. "Asymmetric C–Heteroatom Bond Formation." In Organic Synthesis. Oxford University Press, 2015. http://dx.doi.org/10.1093/oso/9780190200794.003.0036.

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Tomislav Rovis at Colorado State University developed (Angew. Chem. Int. Ed. 2012, 51, 5904) an enantioselective catalytic cross-aza-benzoin reaction of aldehydes 1 and N-Boc imines 2. The useful α-amido ketone products 4 were configurationally stable under the reaction conditions. In the realm of asymmetric synthesis, few technologies have been as widely employed as the Ellman chiral sulfonamide auxiliary. Francisco Foubelo and Miguel Yus at the Universidad de Alicante in Spain have adapted (Chem. Commun. 2012, 48, 2543) this approach for the indium-mediated asymmetric allylation of ketimines
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Lesch, John E. "Accommodation and Survival." In The First Miracle Drugs. Oxford University PressNew York, NY, 2006. http://dx.doi.org/10.1093/oso/9780195187755.003.0006.

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Abstract Beginning in 1935, research on sulfonamides at Elberfeld proceeded in a changed environment. With the wraps off Prontosil, I.G. Farben’s product was exposed to international competition both in the marketplace and in research laboratories. In France, where German patents were not recognized, a copy of Prontosil soon went on the market under the trade name Rubiazol. After the therapeutic action of sulfanilamide was made known by the Pasteur Institute team in November 1935, the new “fragment” compound could be used in place of its parent, and the way was opened for development of a seco
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Reeves, David S., and Les O. Whitea. "Antimicrobial assays." In Medical Bacteriology. Oxford University PressOxford, 2003. http://dx.doi.org/10.1093/oso/9780199637799.003.0008.

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Abstract An antibiotic was originally defined as a substance produced by a micro-organism which inhibited the growth of other micro-organisms. However many drugs loosely referred to as antibiotics are semi-synthetic derivatives of natural antibiotics (e.g. various penicillins and cephalosporins) or compounds produced solely by chemical means (e.g. sulfonamides, 4-quinolones). In addition there are true antibiotics which have useful anticancer rather than antimicrobial properties. For this reason it has become customary to refer to antimicrobial antibiotics and other antimicrobial drugs as anti
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Ostrowska, K., and A. Kolasa. "Synthesis from N-Thioacylated or N-Acylated Sulfonamides or Amides." In Three Carbon-Heteroatom Bonds: Amides and Derivatives; Peptides; Lactams. Georg Thieme Verlag KG, 2005. http://dx.doi.org/10.1055/sos-sd-022-00596.

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Conference papers on the topic "Sulfonamide Derivatives"

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Muškinja, Jovana M., Jelena S. Katanić Stanković, and Zoran R. Ratković. "SYNTHESIS AND ANTIOXIDANT ACTIVITY OF SOME NEW SULFONAMIDE DERIVATIVES." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.351m.

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Sulfonamide derivatives are a very important class of compounds with pronounced biological activities and, for this reason, they have very useful pharmaceutical applications. They are the basis of several groups of drugs and are known as sulfa-drugs. From this point of view, the present study focuses on the synthesis of some novel structural hybrids incorporating two very important groups, sulfonamide, and pyrazoline. The new sulfonamide-based pyrazolines were synthesized in very good yields. The structures of the sulfonamide compounds were confirmed by IR and NMR methods. Synthesized compound
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Petukhov, D., S. Pestova, and E. Izmest’ev. "SYNTHESIS OF SULFONAMIDE DEHYDROABIETANE DERIVATIVES OF AMINO ACIDS." In MedChem-Russia 2021. 5-я Российская конференция по медицинской химии с международным участием «МедХим-Россия 2021». Издательство Волгоградского государственного медицинского университета, 2021. http://dx.doi.org/10.19163/medchemrussia2021-2021-452.

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Deebb, Samara, and Mohammad Sadakaa. "Synthesis of New Amino Acid-Conjugated Derivatives of a Sulphonamide." In 5th International Conference on Biomedical and Health Sciences. Cihan University-Erbil, 2024. http://dx.doi.org/10.24086/biohs2024/paper.1270.

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The subsequent synthesis involved the preparation of novel sulfonamide derivatives from 4-acetamidobenzenesulfanyl chloride. 4-acetamidobenzenesulfanyl chloride was synthesized as the initial compound, followed by the preparation of derivatives through the reaction of 4-acetamidobenzenesulfanyl with the amino acids valine, alanine, and tryptophan using a basic solution of sodium hydroxide. The structures of the derivatives determined by the using FT-IR, 1 H-NMR, 13C-NMR, and DEPT 135o analysis. In addition, the derivatives were also evaluated for their antimicrobial effectiveness against signi
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Mangalagiu, Violeta, Dumitrela Diaconu, and Ionel Mangalagiu. "Quinoline - sulfonamide - complexes with antimicrobial activity." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab26.

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Quinoline-sulfonamide-complexes with variously metals, especially M2+, are a relatively new class of compounds with potential practical interest as fluorescent materials (having fotoluminiscent properties) and also as drugs (having a large variety of biological activities such as antibacterial, antifungal, antiprotozoals, etc.). The emphasis of this work was to obtain hybrid quinoline – sulfonamide - complexes with antimicrobial activity. The synthesis of the hybrid derivatives is direct and efficient, in two steps: acylation of variously amino-quinoline followed by metal complexation with dif
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Yu, Meng, Qing Sun, Ling Sun, Renyong Zhao, and Jinhu Wang. "Determination of 4-Sulfonamidophenylhydrazine and Sulfonamide in Diarylpyrazole Derivatives by LC-MS." In The International Conference on Biomedical Engineering and Bioinformatics. SCITEPRESS - Science and Technology Publications, 2022. http://dx.doi.org/10.5220/0011375300003443.

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Yousif, Ola B., Dhafer S. Zinad, M. S. Ali, and Ayad Tariq Mahmood. "Synthesis and antibacterial screening of novel benzene sulfonamide derivatives through multicomponent Mannich reaction." In 4TH INTERNATIONAL CONFERENCE ON INNOVATION IN IOT, ROBOTICS AND AUTOMATION (IIRA 4.0). AIP Publishing, 2025. https://doi.org/10.1063/5.0255227.

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Dimić, Dušan, Dejan Milenković, Edina Avdović, Goran Kaluđerović, and Jasmina Dimitrić Marković. "MOLECULAR DOCKING AND MOLECULAR DYNAMICS STUDIES OF THE INTERACTION BETWEEN COUMARIN-NEUROTRANSMITTER DERIVATIVES AND CARBONIC ANHYDRASE IX." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac,, 2021. http://dx.doi.org/10.46793/iccbi21.056d.

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Novel biologically active compounds can be obtained by the structural modification of coumarins. In this contribution, five new derivatives of 4-hydroxycoumarin with tyramine, octopamine, norepinephrine, 3-methoxytyramine, and dopamine were obtained. Their structures were optimized based on the previously obtained crystal structure of the 4-hydroxycoumarin-dopamine derivative. The special emphasis was put on the effect of various substituents on the structure of obtained compounds and intramolecular interactions governing the stability. To investigate their possible antitumor activity, molecul
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Owa, Takashi, Rie Ushijima-Sugano, Akira Yokoi, et al. "Abstract 580: Chemical transcriptomic analysis illuminates a class of anticancer sulfonamide derivatives undergoing clinical investigation." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-580.

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Uhlemann, Thomas, Christian Müller, and Sebastian Seidel. "CONFORMER-SPECIFIC IR SPECTROSCOPY OF LASER-DESORBED SULFONAMIDE DRUGS: TAUTOMERIC AND CONFORMATIONAL PREFERENCES OF SULFANILAMIDE AND ITS DERIVATIVES." In 72nd International Symposium on Molecular Spectroscopy. University of Illinois at Urbana-Champaign, 2017. http://dx.doi.org/10.15278/isms.2017.wc10.

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Jádna Silva Frederico, Marisa, Paola Miranda Sulis, Alessandra Mascarello, et al. "Mechanism of action of derivative sulfonamide in glucose tolerance and in incretin and insulin secretion." In Simpósio de Bioquímica e Biotecnologia. Galoa, 2017. http://dx.doi.org/10.17648/simbbtec-2017-80941.

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