Academic literature on the topic 'Sulfonamido Dithiocarbamates'

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Journal articles on the topic "Sulfonamido Dithiocarbamates"

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Alagiri, Kaliyamoorthy, та Kandikere Ramaiah Prabhu. "Catalyst-Free Regio- and Stereospecific Synthesis of β-Sulfonamido Dithiocarbamates: Efficient Ring-Opening Reactions of N-Tosyl Aziridines by Dialkyldithiocarbamates". Chemistry - A European Journal 17, № 25 (2011): 6922–25. http://dx.doi.org/10.1002/chem.201100817.

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Alagiri, Kaliyamoorthy, та Kandikere Ramaiah Prabhu. "ChemInform Abstract: Catalyst-Free Regio- and Stereospecific Synthesis of β-Sulfonamido Dithiocarbamates: Efficient Ring-Opening Reactions of N-Tosyl Aziridines by Dialkyldithiocarbamates." ChemInform 42, № 41 (2011): no. http://dx.doi.org/10.1002/chin.201141045.

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Fu, Dong-Jun, Ying-Chao Liu, Jia-Jia Yang, et al. "Design and Synthesis of Sulfonamide-1,2,3-Triazole Derivatives Bearing a Dithiocarbamate Moiety as Antiproliferative Agents." Journal of Chemical Research 41, no. 9 (2017): 523–25. http://dx.doi.org/10.3184/174751917x15027935057950.

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A series of nine novel 1-(4′-sulfamoylphenyl)-1,2,3-triazole derivatives bearing a 4-dithiocarbamylmethyl moiety were designed using the molecular hybridisation approach and synthesised by alkyne/azide click chemistry. Most of the synthesised compounds exhibited moderate to good antiproliferative activity against oesophagus, gastric and prostate cancer cell lines, but a compound containing a 4-( t-butoxycarbonyl)piperazinylthiocarbonyl moiety showed the highest activity. Against a prostate cancer cell line, it had an IC50 value of 2.4 μM, about 10-fold more active than 5-flurouracil. This work
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D'Ambrosio, Katia, Claudiu T. Supuran, and Giuseppina De Simone. "Are Carbonic Anhydrases Suitable Targets to Fight Protozoan Parasitic Diseases?" Current Medicinal Chemistry 25, no. 39 (2019): 5266–78. http://dx.doi.org/10.2174/0929867325666180326160121.

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Protozoans belonging to Plasmodium, Leishmania and Trypanosoma genera provoke widespread parasitic diseases with few treatment options and many of the clinically used drugs experiencing an extensive drug resistance phenomenon. In the last several years, the metalloenzyme Carbonic Anhydrase (CA, EC 4.2.1.1) was cloned and characterized in the genome of these protozoa, with the aim to search for a new drug target for fighting malaria, leishmaniasis and Chagas disease. P. falciparum encodes for a CA (PfCA) belonging to a novel genetic family, the η-CA class, L. donovani chagasi for a β-CA (LdcCA)
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Supuran, Claudiu T. "Emerging role of carbonic anhydrase inhibitors." Clinical Science 135, no. 10 (2021): 1233–49. http://dx.doi.org/10.1042/cs20210040.

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Abstract Inhibition of carbonic anhydrase (CA, EC 4.2.1.1) was clinically exploited for decades, as most modern diuretics were obtained considering as lead molecule acetazolamide, the prototypical CA inhibitor (CAI). The discovery and characterization of multiple human CA (hCA) isoforms, 15 of which being known today, led to new applications of their inhibitors. They include widely clinically used antiglaucoma, antiepileptic and antiobesity agents, antitumor drugs in clinical development, as well as drugs for the management of acute mountain sickness and idiopathic intracranial hypertension (I
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Zoppi, Carlotta, Alessio Nocentini, Claudiu T. Supuran, Alessandro Pratesi, and Luigi Messori. "Native mass spectrometry of human carbonic anhydrase I and its inhibitor complexes." JBIC Journal of Biological Inorganic Chemistry 25, no. 7 (2020): 979–93. http://dx.doi.org/10.1007/s00775-020-01818-8.

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Abstract Native mass spectrometry is a potent technique to study and characterize biomacromolecules in their native state. Here, we have applied this method to explore the solution chemistry of human carbonic anhydrase I (hCA I) and its interactions with four different inhibitors, namely three sulfonamide inhibitors (AAZ, MZA, SLC-0111) and the dithiocarbamate derivative of morpholine (DTC). Through high-resolution ESI-Q-TOF measurements, the native state of hCA I and the binding of the above inhibitors were characterized in the molecular detail. Native mass spectrometry was also exploited to
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Sağlık, Begüm Nurpelin, Derya Osmaniye, Ulviye Acar Çevik, et al. "Synthesis, characterization and carbonic anhydrase I and II inhibitory evaluation of new sulfonamide derivatives bearing dithiocarbamate." European Journal of Medicinal Chemistry 198 (July 2020): 112392. http://dx.doi.org/10.1016/j.ejmech.2020.112392.

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Quero, Javier, José Carlos Royo, Beatrice Fodor, et al. "Sulfonamide-Derived Dithiocarbamate Gold(I) Complexes Induce the Apoptosis of Colon Cancer Cells by the Activation of Caspase 3 and Redox Imbalance." Biomedicines 10, no. 6 (2022): 1437. http://dx.doi.org/10.3390/biomedicines10061437.

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Two new families of dithiocarbamate gold(I) complexes derived from benzenesulfonamide with phosphine or carbene as ancillary ligands have been synthesized and characterized. In the screening of their in vitro activity on human colon carcinoma cells (Caco-2), we found that the more lipophilic complexes—those with the phosphine PPh3—exhibited the highest anticancer activity whilst also displaying significant cancer cell selectivity. [Au(S2CNHSO2C6H5)(PPh3)] (1) and [Au(S2CNHSO2-p-Me-C6H4)(IMePropargyl)] (8) produce cell death, probably by intrinsic apoptosis (mitochondrial membrane potential mod
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Iwakawa, Tsuneo, Tomohiro Sato, and Akira Murabayashi. "Cycloaddition in Synthesis of Sulfonamide Derivatives. VI Unexpected Products from the Reaction of Dithiocarbamate with Chlorosulfonyl Isocyanate a Novel Synthetic Route to 5-Amino-1,2,4-dithiazol-3-one and N,N-Disubstituted N'-Chlorosulfonylcarbamimidoyl Chloride." HETEROCYCLES 38, no. 5 (1994): 1015. http://dx.doi.org/10.3987/com-93-6641.

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IWAKAWA, T., T. SATO, and A. MURABAYASHI. "ChemInform Abstract: Cycloaddition in Synthesis of Sulfonamide Derivatives. Part 6. Unexpected Products from the Reaction of Dithiocarbamate with Chlorosulfonyl Isocyanate. A Novel Synthetic Route to 5-Amino-1,2,4- dithiazol-3-one and N,N-Disubstituted N′." ChemInform 25, no. 32 (2010): no. http://dx.doi.org/10.1002/chin.199432163.

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Dissertations / Theses on the topic "Sulfonamido Dithiocarbamates"

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Rodriguez-Garcia, Valerie. "Efficient methodology for the synthesis of 2,4-benzodiazepin-1-ones, sulfonylbenzotriazoles, sulfonamides, ethylene sulfonamides, thiocarbamates, dithiocarbamates and thioamides." [Gainesville, Fla.] : University of Florida, 2004. http://purl.fcla.edu/fcla/etd/UFE0006303.

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Alagiri, K. "Metal-Mediated And Metal-Free Organic Transformations : C-H Functionalization Of Tertiary Amines, Synthesis Of Carbonyl Compounds And Ring-Opening Of Aziridines." Thesis, 2011. https://etd.iisc.ac.in/handle/2005/2061.

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Alagiri, K. "Metal-Mediated And Metal-Free Organic Transformations : C-H Functionalization Of Tertiary Amines, Synthesis Of Carbonyl Compounds And Ring-Opening Of Aziridines." Thesis, 2011. http://hdl.handle.net/2005/2061.

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