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1

Manu, G. "Critical Analysis of Dr. B R Ambedkar's Vision." AKSHARASURYA JOURNAL 06, no. 05 (2025): 282 to 293. https://doi.org/10.5281/zenodo.15504841.

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The focus of this study is intended to identify the critical analysis of Ambedkar’s idea in the stimulus vision of modern concepts. The acceleration of those visions has created a common bearing of things that may polish remaining restructured questions to ask through the fundamental social opportunities, equalities, democratic conservation and representation possibility in the matter of re-union of constitutional sustainability and integrity of sovereign ruling with or without political stamina. Provided that the critical intensity has made a clear picture of responsible tact and non-re
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2

Al-Gburi, Ahmed Jamal Abdullah, Zahriladha Zakaria, Hussein Alsariera, et al. "Broadband Circular Polarised Printed Antennas for Indoor Wireless Communication Systems: A Comprehensive Review." Micromachines 13, no. 7 (2022): 1048. http://dx.doi.org/10.3390/mi13071048.

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With the rapid changes in wireless communication systems, indoor wireless communication (IWC) technology has undergone tremendous development. Antennas are crucial components of IWC systems that transmit and receive signals within indoor environments. Thus, the development of indoor technology is highly dependent on the development of indoor antennas. However, indoor environments with limited space require the fewest indoor antenna units and the smallest indoor antenna sizes possible. Hence, indoor antennas with compact size and broad applications have become widely preferred. In an IWC system
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3

Nye-Wood, Mitchell G., Keren Byrne, Sally Stockwell, Angéla Juhász, Utpal Bose, and Michelle L. Colgrave. "Low Gluten Beers Contain Variable Gluten and Immunogenic Epitope Content." Foods 12, no. 17 (2023): 3252. http://dx.doi.org/10.3390/foods12173252.

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Gluten content labels inform food choice and people practicing a gluten-free diet rely upon them to avoid illness. The regulations differ between jurisdictions, especially concerning fermented foodstuffs such as beer. Gluten abundance is typically measured using ELISAs, which have come into question when testing fermented or hydrolysed foodstuffs such as beer. Mass spectrometry can be used to directly identify gluten peptides and reveal false negatives recorded by ELISA. In this survey of gluten in control and gluten-free beers, gluten protein fragments that contain known immunogenic epitopes
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4

Chandramohan, Dinesh Lakshmanan, Krishanu Roy, Hafez Taheri, Michail Karpenko, Zhiyuan Fang, and James B. P. Lim. "A State of the Art Review of Fillet Welded Joints." Materials 15, no. 24 (2022): 8743. http://dx.doi.org/10.3390/ma15248743.

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Fillet welded joints are commonly used in steel structures for various engineering applications such as buildings, bridges, railways, ships, and marine structures. Fillet welded joints are generally subjected to static and fatigue loading, resulting in failures of such welded joints. A number of experimental and numerical investigations on the strength and failure behaviour of fillet welded joints have been published. This paper presents a comprehensive review of research results on the static strength, fatigue life, and thermal performance of fillet welded joints. The review covers the variou
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Atilla, Erden, Pervin Topcuoglu, Erman Akkus, et al. "Impact of ABO Mismatch on Outcomes of Allogeneic Hematopoietic Stem Cell Recipients: 30 Years of Experience with 1016 Patients." Blood 132, Supplement 1 (2018): 3472. http://dx.doi.org/10.1182/blood-2018-99-118314.

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Abstract Introduction: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is widely used to treat malignant and non-malignant hematological diseases. The impact of ABO mismatch on outcome following transplantation remains controversial. In this study, our aim is to define effects of ABO mismatch on engraftment, graft vs host disease, relapse free survival (RFS) and overall survival (OS) in patients who underwent allo-HSCT. Patients and Methods: Between 1988 and 2016, we retrospectively identified 1016 patients who underwent allo-HSCT at Ankara University School of Medicine, Departm
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Koshy, RM, EG Kane, and C. Grocock. "A review of the use of biological mesh products in modern UK surgical practice: a religious and cultural perspective." Annals of The Royal College of Surgeons of England 102, no. 8 (2020): 566–70. http://dx.doi.org/10.1308/rcsann.2020.0114.

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Introduction The UK is an increasingly multicultural society. This change coincides with an increasing use of animal products in medicine and surgery and a change in the UK law of consent. The refusal of Jehovah’s Witnesses to accept blood products is well known, but the use of animal products in surgery is a neglected topic. As society becomes more diverse and medicine becomes ever more advanced, there is increasing potential for a mismatch between what is medically possible and what is acceptable from a religious perspective. Methods Surgical products were identified by searching the literat
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7

Guo, Wenxian, Chenyi Qin, and Zhongyu Shi. "Policy Issues and Prospects for the Development of China's Long-term Care Insurance System: Taking Shanghai as an Example." Transactions on Social Science, Education and Humanities Research 12 (August 29, 2024): 46–51. http://dx.doi.org/10.62051/wwahzf56.

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At present, Shanghai is the earliest city that entered the aging society and the large city with the highest aging degree in China. Over the past 30 years, the total number of elderly population in Shanghai has increased dramatically and the degree of aging has developed rapidly. The current long-term care (LTC) insurance policy has been piloted in Shanghai for six years. This paper understands and analyses the current situation of LTC insurance in Shanghai from various aspects related to LTC insurance, and provides a strategic direction for improving LTC insurance from the level of service an
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8

Richard, Guy-Franck. "The Startling Role of Mismatch Repair in Trinucleotide Repeat Expansions." Cells 10, no. 5 (2021): 1019. http://dx.doi.org/10.3390/cells10051019.

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Trinucleotide repeats are a peculiar class of microsatellites whose expansions are responsible for approximately 30 human neurological or developmental disorders. The molecular mechanisms responsible for these expansions in humans are not totally understood, but experiments in model systems such as yeast, transgenic mice, and human cells have brought evidence that the mismatch repair machinery is involved in generating these expansions. The present review summarizes, in the first part, the role of mismatch repair in detecting and fixing the DNA strand slippage occurring during microsatellite r
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9

Ruan, Zihan. "Reasons and solutions for device mismatch and structural mismatch in electronic circuits." Applied and Computational Engineering 101, no. 1 (2024): 207–12. http://dx.doi.org/10.54254/2755-2721/101/20241045.

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Abstract. Integrated circuits have become one of the most popular industries in recent years, and more and more fields are interacting with it. With the passage of time, various new circuit designs have been created, and layout designs continue to advance. People are increasingly concerned about the accuracy and stability of devices, and the use of devices is also increasing. Circuit mismatch is starting to be a concern. This article based on three levels, discussed the most basic device-level resistor and capacitor mismatches at first, then talked about the circuit structures that improve the
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10

Badmos, Kamorudeen Abiola, Chiedozie James Alumona, and Babatunde O. A. Adegoke. "Mismatch between classroom furniture dimensions and anthropometric measures of public primary school children in Ibadan, Nigeria." Ergonomics SA 33, no. 1 (2022): 1–11. http://dx.doi.org/10.4314/esa.v33i1.2.

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This study explored the compatibility of classroom furniture with the anthropometric parameters of public primary school children in Ibadan. The study involved 900 primary school children (aged 5 – 13 years) randomly selected from one school. The students’ anthropometric parameters and the school furniture dimensions were measured using Cescorf Sliding Broad-blade Caliper and metallic tape respectively. Frequency tables were used to summarise mismatches and compatibility. All participants in the 5 – 7-year-old group had mismatches between popliteal height/seat height, buttock to popliteal leng
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11

Sandhu, Karamjeet S., Ketevan Gendzekhadze, Dongyun Yang, et al. "Prediction of Graft-Versus-Host Disease in Recipients of Single Mismatched Unrelated Hematopoietic Cell Transplantation Donor Using a Highly Multiplexed Proteomic Assay, MHC-Pepseq." Blood 138, Supplement 1 (2021): 1808. http://dx.doi.org/10.1182/blood-2021-153597.

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Abstract Graft-versus-host disease (GVHD) remains a major cause of treatment failure after allogeneic hematopoietic cell transplantation (alloHCT). In HLA-mismatched donor setting, indirect presentation of allogeneic peptides from recipient's mismatched HLA class I or II proteins by donor or recipient antigen presenting cells can be an immunogenic driver of GVHD. However, the potential diversity of such antigens is large, and predicting them in a systematic manner has proven challenging. Using a novel, highly-multiplexed peptide-MHC binding assay (MHC-PepSeq) we sought to 1) identify allogenei
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12

Hussain, Muzamil, Syed Hasan Askari Rizvi, Naseem Abbas, et al. "Recent Developments in Coatings for Orthopedic Metallic Implants." Coatings 11, no. 7 (2021): 791. http://dx.doi.org/10.3390/coatings11070791.

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Titanium, stainless steel, and CoCrMo alloys are the most widely used biomaterials for orthopedic applications. The most common causes of orthopedic implant failure after implantation are infections, inflammatory response, least corrosion resistance, mismatch in elastic modulus, stress shielding, and excessive wear. To address the problems associated with implant materials, different modifications related to design, materials, and surface have been developed. Among the different methods, coating is an effective method to improve the performance of implant materials. In this article, a comprehe
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13

Kornblit, Brian, Barry Storer, Michael B. Maris, et al. "Sirolimus Combined with Cyclosporine (CSP) and Mycophenolate Mofetil (MMF) As Graft-Vs-Host Disease (GVHD) Prophylaxis after Nonmyeloablative (NMA) Hematopoietic Cell Transplantation (HCT) Using HLA Class I or Class II Antigen Mismatched Donors: Results from a Phase II Multi-Center Trial." Blood 134, Supplement_1 (2019): 369. http://dx.doi.org/10.1182/blood-2019-123196.

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The success of HCT is highly dependent on the availability of compatible donors. Depending on ethnicity, fully HLA-matched donors cannot be identified for 25-84% of patients. In an effort to extend the use of HLA-mismatched donors to patients only eligible for NMA HCT, we previously demonstrated that engraftment and long-term survival can be achieved using CSP and MMF immunosuppression after HLA class I antigen-mismatched HCT (Nakamae et al, 2010). Based on this trial, we designed a phase II multi-center trial to assess the efficacy of GVHD prophylaxis with triple immune suppression with CSP,
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14

Kumaravel, Girthana, and Swamynathan Sankaranarayanan. "PQPS: Prior-Art Query-Based Patent Summarizer Using RBM and Bi-LSTM." Mobile Information Systems 2021 (December 28, 2021): 1–19. http://dx.doi.org/10.1155/2021/2497770.

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A prior-art search on patents ascertains the patentability constraints of the invention through an organized review of prior-art document sources. This search technique poses challenges because of the inherent vocabulary mismatch problem. Manual processing of every retrieved relevant patent in its entirety is a tedious and time-consuming job that demands automated patent summarization for ease of access. This paper employs deep learning models for summarization as they take advantage of the massive dataset present in the patents to improve the summary coherence. This work presents a novel appr
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15

Macquistan, D. A., I. C. Bassignana, A. J. SpringThorpe, R. Packwood, and V. Moore. "X-Ray DCD and EPMA Measurements of Al Concentration in Epitaxial AlxGa1-xAs/GaAs Layers." Advances in X-ray Analysis 36 (1992): 221–29. http://dx.doi.org/10.1154/s0376030800018826.

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AbstractDouble Crystal X-Ray Diffraction (DCD) is often used to determine the Al content of AlxGa1-xAs/GaAs epitaxial layers. Assessing composition from a measurement of mismatch is problematic because it invokes a number of assumptions. This study bypasses these difficulties by comparing the measurement of mismatch directly with Al composition measurements made by electronprobe microanalysis. A study of coherent epitaxial AlxGa1-xAs layers showed that mismatch varies linearly with composition. The equation Al (x) = |ΔΘ| / 368 summarizes the relationship over the coherent range, where |ΔΘ| is
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16

Vrána, David, Marcel Matzenauer, Čestmír Neoral, et al. "From Tumor Immunology to Immunotherapy in Gastric and Esophageal Cancer." International Journal of Molecular Sciences 20, no. 1 (2018): 13. http://dx.doi.org/10.3390/ijms20010013.

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Esophageal and gastric cancers represent tumors with poor prognosis. Unfortunately, radiotherapy, chemotherapy, and targeted therapy have made only limited progress in recent years in improving the generally disappointing outcome. Immunotherapy with checkpoint inhibitors is a novel treatment approach that quickly entered clinical practice in malignant melanoma and renal cell cancer, but the role in esophageal and gastric cancer is still poorly defined. The principal prognostic/predictive biomarkers for immunotherapy efficacy currently considered are PD-L1 expression along with defects in misma
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17

Perevoztchikova, S. A., E. A. Romanova, T. S. Oretskaya, P. Friedhoff, and E. A. Kubareva. "Modern Aspects of the Structural and Functional Organization of the DNA Mismatch Repair System." Acta Naturae 5, no. 3 (2013): 17–34. http://dx.doi.org/10.32607/20758251-2013-5-3-17-34.

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This review is focused on the general aspects of the DNA mismatch repair (MMR) process. The key proteins of the DNA mismatch repair system are MutS and MutL. To date, their main structural and functional characteristics have been thoroughly studied. However, different opinions exist about the initial stages of the mismatch repair process with the participation of these proteins. This review aims to summarize the data on the relationship between the two MutS functions, ATPase and DNA-binding, and to systematize various models of coordination between the mismatch site and the strand discriminati
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18

Yang, Ye. "The Construction of Free Trade Zones Will Invest and Finance for China’s Enterprises Study on the Impact of Maturity Mismatch." Journal of Management and Social Development 1, no. 6 (2024): 89–97. https://doi.org/10.62517/jmsd.202412613.

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With the intensification of market competition, the investment and financing risks of enterprises increase, especially the maturity mismatch may lead to the rupture of capital flow and affect the stable development of enterprises. This paper studies how the free trade zone affects the maturity mismatch of enterprise investment and financing. The paper first summarizes the influencing factors of the establishment of free trade zone and the mismatch of enterprise investment and financing period, and then defines the mismatch between pilot free trade zone and enterprises, and puts forward the res
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19

Zhang, Xinghui, Qili Shi, Lingai Luo, Yilin Fan, Qian Wang, and Guanguan Jia. "Research Progress on the Phase Change Materials for Cold Thermal Energy Storage." Energies 14, no. 24 (2021): 8233. http://dx.doi.org/10.3390/en14248233.

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Thermal energy storage based on phase change materials (PCMs) can improve the efficiency of energy utilization by eliminating the mismatch between energy supply and demand. It has become a hot research topic in recent years, especially for cold thermal energy storage (CTES), such as free cooling of buildings, food transportation, electronic cooling, telecommunications cooling, etc. This paper summarizes the latest research progress of the PCMs-based CTES. Firstly, the classification of PCMs for low temperature storage is introduced; the thermal physical properties (e.g., phase change temperatu
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20

Jain, Rajan, Derek R. Johnson, Sohil H. Patel, et al. "“Real world” use of a highly reliable imaging sign: “T2-FLAIR mismatch” for identification of IDH mutant astrocytomas." Neuro-Oncology 22, no. 7 (2020): 936–43. http://dx.doi.org/10.1093/neuonc/noaa041.

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Abstract AbstractThe T2-FLAIR (fluid attenuated inversion recovery) mismatch sign is an easily detectable imaging sign on routine clinical MRI studies that suggests diagnosis of isocitrate dehydrogenase (IDH)–mutant 1p/19q non-codeleted gliomas. Multiple independent studies show that the T2-FLAIR mismatch sign has near-perfect specificity, but low sensitivity for diagnosing IDH-mutant astrocytomas. Thus, the T2-FLAIR mismatch sign represents a non-invasive radiogenomic diagnostic finding with potential clinical impact. Recently, false positive cases have been reported, many related to variable
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21

Wang, Liping, Cifang Wu, and Songnian Zhao. "A Review of Spatial Mismatch Research: Empirical Debate, Theoretical Evolution and Connotation Expansion." Land 11, no. 7 (2022): 1049. http://dx.doi.org/10.3390/land11071049.

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At present, widespread urban expansion, regeneration, and transformation have inevitably led to the spatial separation of residence and employment, and negatively affected the employment welfare of the subjects concerned, which needs to be traced back to the theory of spatial mismatch to explore possible solutions. The theory of spatial mismatch has been proposed for more than sixty years, and its theoretical connotation has been continuously expanded through the heated debate on its objective existence. However, due to the lack of understanding of its expansion process and the essence of its
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22

Caja, Fabian, Ludmila Vodickova, Jan Kral, Veronika Vymetalkova, Alessio Naccarati, and Pavel Vodicka. "DNA Mismatch Repair Gene Variants in Sporadic Solid Cancers." International Journal of Molecular Sciences 21, no. 15 (2020): 5561. http://dx.doi.org/10.3390/ijms21155561.

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The phenotypic effects of single nucleotide polymorphisms (SNPs) in the development of sporadic solid cancers are still scarce. The aim of this review was to summarise and analyse published data on the associations between SNPs in mismatch repair genes and various cancers. The mismatch repair system plays a unique role in the control of the genetic integrity and it is often inactivated (germline and somatic mutations and hypermethylation) in cancer patients. Here, we focused on germline variants in mismatch repair genes and found the outcomes rather controversial: some SNPs are sometimes ascri
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Lee, Su Hyeon, Jong Won Lee, Daehyeon Kim, Gi Doo Cha, and Sung-Hyuk Sunwoo. "Recent Achievements of Epicardial Patch Electronics Using Adhesive and Conductive Hydrogels." Gels 11, no. 7 (2025): 530. https://doi.org/10.3390/gels11070530.

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Implantable cardiac devices are critical in improving patients’ quality of life through precise and continuous interaction between the device and pathological cardiac tissue. Due to the inherently rigid nature of conventional devices, several complications arise when interacting with soft cardiac tissue, caused by a mechanical mismatch between the device and myocardium. This leads to the excessive formation of fibrous tissue around the implanted device, ultimately compromising both device functionality and tissue health. To address these challenges, flexible electronics based on polymers and e
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Guo, Jianing. "Analysis of Current Imbalance in Paralleled Silicon Carbide Power MOSFETs." Academic Journal of Science and Technology 3, no. 3 (2022): 247–54. http://dx.doi.org/10.54097/ajst.v3i3.2992.

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In order to adapt to the application scenarios of high power variable current, it is an effective solution to parallel multiple silicon carbide (SiC) power. However, the static parameters of SiC MOSFET devices are dispersed, the parasitic parameters of power loop are asymmetric, and the working junction temperature of the devices is different. All these factors will lead to non-uniform current stress between parallel devices.This article is based on the SiC MOSFET device provided in Wolfspeed,to explore the impact of circuit parameters mismatch on current sharing in parallel components. The in
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25

Yengopal, V. "What’s new for the clinician – summaries of recently published papers (April 2023)." South African Dental Journal 78, no. 03 (2023): 156–63. http://dx.doi.org/10.17159/sadj.v78i03.16266.

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Dental implants are a common treatment modality that is offered to many patients. There is therefore a good chance that many oral health professionals (dentists, dental therapists, oral hygienists, dental specialists) will encounter such patients in their private or public dental clinics. Barrak and colleagues (2023)1 have highlighted the mismatch between the knowledge and skill requirement of the general dental practitioner (GDP) in managing such patients and the training provided at undergraduate (UG) and general postgraduate (PG) levels. Studies in the UK among dental schools there and in I
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Wang, Wei Bing, He Xue, Fu Qiang Yang, and Xu Sheng Zhou. "Characteristic of Interface Crack Propagation in Dissimilar Weld Joints." Advanced Materials Research 988 (July 2014): 249–52. http://dx.doi.org/10.4028/www.scientific.net/amr.988.249.

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The propagation behavior of crack with different initiation position is affected by the constraint effect differences in dissimilar weld joints mechanical heterogeneity. The ductile fracture model of interface crack in dissimilar weld joints was built by adopting extended finite element method; the propagation characteristic of interface crack was summarized. The results indicate that the strength mismatch of materials at sides of interface will increase trend of crack advancing into the relative soft material which has lower yield strength and lower hardening exponent.
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27

Kaplan, Alanna R., and Peter M. Glazer. "Impact of hypoxia on DNA repair and genome integrity." Mutagenesis 35, no. 1 (2019): 61–68. http://dx.doi.org/10.1093/mutage/gez019.

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Abstract Hypoxia is a hallmark of the tumour microenvironment with profound effects on tumour biology, influencing cancer progression, the development of metastasis and patient outcome. Hypoxia also contributes to genomic instability and mutation frequency by inhibiting DNA repair pathways. This review summarises the diverse mechanisms by which hypoxia affects DNA repair, including suppression of homology-directed repair, mismatch repair and base excision repair. We also discuss the effects of hypoxia mimetics and agents that induce hypoxia on DNA repair, and we highlight areas of potential cl
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Elez, Marina. "Mismatch Repair: From Preserving Genome Stability to Enabling Mutation Studies in Real-Time Single Cells." Cells 10, no. 6 (2021): 1535. http://dx.doi.org/10.3390/cells10061535.

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Mismatch Repair (MMR) is an important and conserved keeper of the maintenance of genetic information. Miroslav Radman’s contributions to the field of MMR are multiple and tremendous. One of the most notable was to provide, along with Bob Wagner and Matthew Meselson, the first direct evidence for the existence of the methyl-directed MMR. The purpose of this review is to outline several aspects and biological implications of MMR that his work has helped unveil, including the role of MMR during replication and recombination editing, and the current understanding of its mechanism. The review also
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Hale, Gregory A., Smriti Shrestha, Jennifer LeRademacher, et al. "Alternative Donor Hematopoietic Cell Transplantation (HCT) After Reduced Intensity (RIC) or Nonmyeloablative (NST) Conditioning in Advanced Non-Hodgkin Lymphoma (NHL)." Blood 114, no. 22 (2009): 3380. http://dx.doi.org/10.1182/blood.v114.22.3380.3380.

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Abstract Abstract 3380 Poster Board III-268 For adult allogeneic HCT candidates lacking a matched family donor, an alternative donor (unrelated or mismatched family) remains the most feasible option. Lower intensity conditioning using RIC or NST regimens is increasingly used in NHL to lower transplant related mortality (TRM) while retaining graft vs. lymphoma effect. We analyzed the outcomes of 248 (61% male) adult recipients of HCT for NHL from alternative donors after RIC/NMA conditioning reported to the CIBMTR from 1997 to 2004. Recipients of any prior transplants and those in first complet
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Deshpande, Madhura, Phillip A. Romanski, Zev Rosenwaks, and Jeannine Gerhardt. "Gynecological Cancers Caused by Deficient Mismatch Repair and Microsatellite Instability." Cancers 12, no. 11 (2020): 3319. http://dx.doi.org/10.3390/cancers12113319.

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Mutations in mismatch repair genes leading to mismatch repair (MMR) deficiency (dMMR) and microsatellite instability (MSI) have been implicated in multiple types of gynecologic malignancies. Endometrial carcinoma represents the largest group, with approximately 30% of these cancers caused by dMMR/MSI. Thus, testing for dMMR is now routine for endometrial cancer. Somatic mutations leading to dMMR account for approximately 90% of these cancers. However, in 5–10% of cases, MMR protein deficiency is due to a germline mutation in the mismatch repair genes MLH1, MSH2, MSH6, PMS2, or EPCAM. These ger
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Gérard, Maxence, Maryse Vanderplanck, Thomas Wood, and Denis Michez. "Global warming and plant–pollinator mismatches." Emerging Topics in Life Sciences 4, no. 1 (2020): 77–86. http://dx.doi.org/10.1042/etls20190139.

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The mutualism between plants and their pollinators provides globally important ecosystem services, but it is likely to be disrupted by global warming that can cause mismatches between both halves of this interaction. In this review, we summarise the available evidence on (i) spatial or (ii) phenological shifts of one or both of the actors of this mutualism. While the occurrence of future spatial mismatches is predominantly theoretical and based on predictive models, there is growing empirical evidence of phenological mismatches occurring at the present day. Mismatches may also occur when polli
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Johnson, Eric, Roberto Nussenzveig, Neeraj Agarwal, and Umang Swami. "Germline variants and response to systemic therapy in advanced prostate cancer." Pharmacogenomics 21, no. 1 (2020): 75–81. http://dx.doi.org/10.2217/pgs-2019-0125.

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Our current understanding of prostate cancer pharmacogenomics is growing at a rapid pace. Apart from evaluating relevant biomarkers and genomic alterations in tumor tissues, an increasing focus is being placed on decoding the impact of germline alterations on prostate cancer and its treatment. Herein we summarize various germline variants that have shown to associate with response to systemic therapy in men with advanced prostate cancer. Covered biomarkers include HSD3B1, SLCO2B1, SULT1E1, TRMT11, CYP17A1, CYP1B1, genes involved in homologous recombination and DNA mismatch repair.
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Deschenes, Sarah, Larry Cuban, and David Tyack. "Mismatch: Historical Perspectives on Schools and Students who Don't Fit Them." Teachers College Record: The Voice of Scholarship in Education 103, no. 4 (2001): 525–47. http://dx.doi.org/10.1177/016146810110300401.

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There have always been students who do not meet the educational expectations of their time—students outside the mainstream mold who do not fit dominant notions of success. The differences between schools and these students can be thought of as a “mismatch” between the structure of schools and the social, cultural, or economic backgrounds of students identified as problems. In this essay we examine the history of these students who have not been able to do what educators wanted them to do. We look at how educators have labeled poor school performers in different periods and how these labels ref
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SALAS, F., F. GORDILLO, J. ARACIL, and R. REGINATTO. "CODIMENSION-TWO BIFURCATIONS IN INDIRECT FIELD ORIENTED CONTROL OF INDUCTION MOTOR DRIVES." International Journal of Bifurcation and Chaos 18, no. 03 (2008): 779–92. http://dx.doi.org/10.1142/s0218127408020641.

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This paper provides further results on bifurcation analysis of indirect field oriented control of induction motors. Previous results presented on this subject [Bazanella & Reginatto, 2000, 2001; Gordillo et al., 2002] are summarized and extended by means of a codimension-two bifurcation analysis. It is shown that codimension-two bifurcation phenomena, such as a Bogdanov–Takens and zero–Hopf bifurcations, occur in IFOC as a result of parameter mismatch and certain setting of the proportional-integral speed controller. Conditions for the existence of such bifurcations are derived analyticall
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Zhuang, Haoyu, Xudong Chen, Enzhe Zhang, and Qiang Li. "High-Accuracy Bandgap Reference of <20 ppm/°C: A Review." Chips 4, no. 1 (2025): 5. https://doi.org/10.3390/chips4010005.

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This review discusses the principle of typical bandgap reference circuits and analyzes their sources of errors. In order to provide readers with a clear perspective, we categorize the error sources into four types: (a) amplifier offset; (b) high-order nonlinearity of VBE; (c) current mirror mismatch; and (d) other error sources. For these error sources, the most commonly used methods to reduce or minimize them to achieve high accuracy are summarized. Furthermore, this review explores sub-1V bandgap reference design techniques, addressing the increasing demand for low-power and low-voltage appl
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Jin, Zhaohui, and Frank A. Sinicrope. "Prognostic and Predictive Values of Mismatch Repair Deficiency in Non-Metastatic Colorectal Cancer." Cancers 13, no. 2 (2021): 300. http://dx.doi.org/10.3390/cancers13020300.

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Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide. Universal MMR/MSI testing is standard of care for all patients with newly diagnosed CRC based on multi-society guidelines in the United States. Such testing is intended to identify patients with Lynch Syndrome due to a germline mutation in an MMR gene, but also detects those with sporadic dMMR/MSI-high CRCs. The prognostic utility of MMR/MSI status in non-metastatic colorectal cancer has been studied extensively, yet more limited data are available for its predictive utility. Results have not been entirely consisten
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Li, Lin, and Kecheng Yang. "Research on Occupational Injury Protection System for New Business Practitioners." Frontiers in Business, Economics and Management 2, no. 3 (2021): 11–17. http://dx.doi.org/10.54097/fbem.v2i3.180.

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This paper analyzes the necessity of establishing the occupational injury security system for new forms of business and summarizes the pilot areas of the current occupational injury security sy stem, and then analyzes the problems existing in the current occupational injury security for new forms of business, including the difficulty in identifying labor relations and the mismatch between supply and demand of occupational injury security. Finally, the specific conception of occupational injury protection system for employees in the new form of business is put forward, including open insured ob
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38

Shang, Wen-lan. "Application of Machine Learning and Internet of Things Techniques in Evaluation of English Teaching Effect in Colleges." Computational Intelligence and Neuroscience 2022 (March 19, 2022): 1–9. http://dx.doi.org/10.1155/2022/7643006.

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College English classroom teaching evaluation is one of the key issues discussed by all schools at present. First of all, teachers and students are highly concerned about English learning in the compulsory course of English examination, but there are also many problems. The distance network teaching with computer technology as the main body develops rapidly, a large number of video and audio teaching resources network through the network transmission to present in front of learners, through the network transmission of video and audio aided, expand the audience of network teaching, is conducive
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Johnson, Racheal Louise, Subhasheenee Ganesan, Amudha Thangavelu, et al. "Immune Checkpoint Inhibitors Targeting the PD-1/PD-L1 Pathway in Advanced, Recurrent Endometrial Cancer: A Scoping Review with SWOT Analysis." Cancers 15, no. 18 (2023): 4632. http://dx.doi.org/10.3390/cancers15184632.

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Results of recent clinical trials using the immune check point inhibitors (ICI) pembrolizumab or dostarlimab with/without lenvatinib has led to their approval for specific molecular subgroups of advanced recurrent endometrial cancer (EC). Herein, we summarise the clinical data leading to this first tissue-agnostic approval. As this novel therapy is not yet available in the United Kingdom standard care setting, we explore the strengths, weaknesses, opportunities, and threats (SWOT) of ICI treatment in EC. Major databases were searched focusing on clinical trials using programmed cell death prot
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Wu, Yi, Gang Guo, Zhuxuan Wei, and Jin Qian. "Programming Soft Shape-Morphing Systems by Harnessing Strain Mismatch and Snap-Through Bistability: A Review." Materials 15, no. 7 (2022): 2397. http://dx.doi.org/10.3390/ma15072397.

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Multi-modal and controllable shape-morphing constitutes the cornerstone of the functionalization of soft actuators/robots. Involving heterogeneity through material layout is a widely used strategy to generate internal mismatches in active morphing structures. Once triggered by external stimuli, the entire structure undergoes cooperative deformation by minimizing the potential energy. However, the intrinsic limitation of soft materials emerges when it comes to applications such as soft actuators or load-bearing structures that require fast response and large output force. Many researchers have
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Favier, Amelia, Justine Varinot, Catherine Uzan, Alex Duval, Isabelle Brocheriou, and Geoffroy Canlorbe. "The Role of Immunohistochemistry Markers in Endometrial Cancer with Mismatch Repair Deficiency: A Systematic Review." Cancers 14, no. 15 (2022): 3783. http://dx.doi.org/10.3390/cancers14153783.

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The objective of this systematic review was to summarize our current knowledge of the role of immunohistochemistry (IHC) markers for identifying mismatch repair-deficient (MMRd) tumors in endometrial cancer (EC). Identification of MMRd tumors, which occur in 13% to 30% of all ECs, has become critical for patients with colorectal and endometrial cancer for therapeutic management, clinical decision making, and prognosis. This review was conducted by two authors applying the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines using the following terms: “immunohi
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Tan, Wanxia, Yuelin He, Xiaoqin Feng та ін. "Evolving Selection of Unrelated Donor for Hematopoietic Stem Cell Transplantation for Patients with β Thalassemia". Blood 134, Supplement_1 (2019): 3330. http://dx.doi.org/10.1182/blood-2019-129934.

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Background: Many Chinese patients with hematologic disease, who need allogeneic hematopoietic stem cell transplantation(HSCT) commonly lack an HLA matched sibling since a Chinese family often has a single child due to Chinese one-child policy in the past 10years. As an alternative option, unrelated HSCT is the feasible option for the patients without matched related donors (MRD). Many study have found that thalassemia-free survival (TFS) was approximately 90% in unrelated donor HSCT (UDT) for TM patients. Donor selection is one of key factors for better outcomes after hematopoietic stem cell t
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Kasuga, Akiyoshi, Takeshi Okamoto, Shohei Udagawa, et al. "Molecular Features and Clinical Management of Hereditary Pancreatic Cancer Syndromes and Familial Pancreatic Cancer." International Journal of Molecular Sciences 23, no. 3 (2022): 1205. http://dx.doi.org/10.3390/ijms23031205.

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Hereditary pancreatic cancers are caused by several inherited genes. Familial pancreatic cancer is defined as pancreatic cancer arising in a patient with at least two first-degree relatives with pancreatic cancer in the absence of an identified genetic cause. Hereditary pancreatic cancer syndromes and familial pancreatic cancers account for about 10% of pancreatic cancer cases. Germline mutations in BRCA1, BRCA2, ATM, PALB2, CDKN2A, STK11, and TP53 and mismatch repair genes (MLH1, MSH2, MSH6, PMS2, and EPCAM) are among the well-known inherited susceptibility genes. Currently available targeted
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Strelnikova, S. R., and R. A. Komakhin. "Control of meiotic crossing over in plant breeding." Vavilov Journal of Genetics and Breeding 27, no. 2 (2023): 99–100. http://dx.doi.org/10.18699/vjgb-23-15.

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Meiotic crossing over is the main mechanism for constructing a new allelic composition of individual chromosomes and is necessary for the proper distribution of homologous chromosomes between gametes. The parameters of meiotic crossing over that have developed in the course of evolution are determined by natural selection and do not fully suit the tasks of selective breeding research. This review summarizes the results of experimental studies aimed at increasing the frequency of crossovers and redistributing their positions along chromosomes using genetic manipulations at different stages of m
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Li, Zimu. "Study on the Effect of Different Presentation Methods of Chinese Text with Phonetic Notation." Journal of Education and Educational Research 3, no. 3 (2023): 79–81. http://dx.doi.org/10.54097/jeer.v3i3.9557.

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This study focuses on the effectiveness of the use of annotated texts in international Chinese education. Through text analysis and questionnaire surveys, we investigated the current situation of the use of annotated texts in international Chinese education and summarized the effectiveness of different presentation methods of annotated texts. The study found that: the current Chinese teaching practice has a variety of ways of presenting annotated texts and lacks clear standardization; some teaching materials have more visual factors that are not conducive to reading and learning; some teachers
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Hsu, Jack W., Scott D. Rowley, Stuart L. Goldberg, David S. Siegel, Robert A. Preti, and Andrew L. Pecora. "A Myeloablative Conditioning Regimen Is Required to Produce Durable Engraftment and Immune Reconsitution in Related and Unrelated Multi-Antigen HLA Mismatched Pan-T-Cell Depleted Limited T-Cell Add-Back Transplants." Blood 104, no. 11 (2004): 5185. http://dx.doi.org/10.1182/blood.v104.11.5185.5185.

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Abstract Multi-antigen HLA mismatched transplantation is associated with a high risk of graft failure and graft-vs.-host disease (GVHD), particularly in the unrelated setting. Strategies used to overcome these barriers include high CD34+ dose and T-cell depletion respectively. However, this often results in increased relapse rates and delayed immune reconstitution. We previously reported on four patients without matched donors who were transplanted using a multi-antigen mismatched, pan T-cell depleted donor graft with limited (1x105 CD3+ cells/kg unrelated donor, 1x106 CD3+ cells/kg related do
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Biesiekierski, Arne, James Wang, and Cui'e Wen. "A Brief Review of Biomedical Shape Memory Alloys by Powder Metallurgy." Key Engineering Materials 520 (August 2012): 195–200. http://dx.doi.org/10.4028/www.scientific.net/kem.520.195.

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In the realm of bioimplantation, titanium-based Shape Memory Alloys (SMAs) exhibit phenomenal versatility, with successful application in diverse fields. One area of particular interest is that of orthopaedics, where the unique properties of SMAs offer a range of benefits. That said, existing alloys still have unresolved issues concerning biocompatibility and osseointegration. Primary concerns include carcinogenicity, allergenicity and a significant mismatch between the Young’s moduli of bone and osteoimplants; issues that could be addressed via a novel porous titanium alloy. With that in mind
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Lee, Min A., and Gi Jun Um. "Study correlates visual meaning of military identity and mascots." Korea Institute of Design Research Society 9, no. 3 (2024): 176–90. http://dx.doi.org/10.46248/kidrs.2024.3.176.

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This study analyzes the symbols and mascots of the U.S., Russian, Japanese, and South Korean militaries, among the powers surrounding the Korean Peninsula, to examine the correlation between military identity and visual meaning. The research methodology was to summarize military identity and symbols through each country's military websites and analyze the symbolism, colors, and gestures of the mascots. The results showed that the U.S. military uses animal mascots with strong images to emphasize courage and strength, Russia uses mascots that symbolize national power and glory, Japan's Self-Defe
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Takahashi, Hiroyuki, Katsuzo Hanaoka, Hideo Wada, Daibo Kojima, and Masato Watanabe. "The Current Status of T Cell Receptor (TCR) Repertoire Analysis in Colorectal Cancer." International Journal of Molecular Sciences 26, no. 6 (2025): 2698. https://doi.org/10.3390/ijms26062698.

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The rapid increase in colorectal cancer (CRC) cases recently has highlighted the need to use predictive biomarkers to guide therapeutic approaches. Current studies have focused on the tumor-infiltrating lymphocytes present in the tumor microenvironment (TME), in which cytotoxic T cell activation and the amount are associated with CRC patient prognosis. The T cell receptor (TCR) is essential for antigen recognition and T cell identification, playing a central role in cancer immunotherapy. The T cell status reflects TCR diversity or clonality, known as the TCR repertoire. Accordingly, analyzing
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Ottini, Arianna, Pierangela Sepe, Teresa Beninato, et al. "Biomarker-driven immunotherapy for precision medicine in prostate cancer." Personalized Medicine 19, no. 1 (2022): 51–66. http://dx.doi.org/10.2217/pme-2021-0079.

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Although immunotherapy has recently revolutionized standard of care in different cancer types, prostate cancer has generally failed to show dramatic responses to immune checkpoint inhibitors. As in other tumors, the goal in prostate cancer is now to target treatments more precisely on patient’s individual characteristics through precision medicine. Defects in mismatch repair, mutations in the exonuclease domain of the DNA polymerase epsilon ( POLE), high tumor mutational burden and the presence of biallelic loss of CDK12 among others, are predictive biomarkers of response to immunotherapy. In
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