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1

Li, Kexuan, Yuanyuan Cai, Shu Xie, et al. "Evidence Summary for Nonpharmacological Management of Chemotherapy-Induced Nausea and Vomiting." BioMed Research International 2022 (November 23, 2022): 1–10. http://dx.doi.org/10.1155/2022/4741193.

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Objective. To evaluate and summarize the best evidence for nonpharmacological management of chemotherapy induced nausea and vomiting (CINV). This article aims at serving as a reference for nursing staff to prevent and manage CINV. Methods. We systematically searched for evidence on CINV in databases such as Cnki and Wanfang, guide websites such as GIN and NZGG, and professional websites such as UICC and ACS. Only articles published between November 2012 and November 2021 were considered for inclusion in the summary. Two researchers evaluated the quality of the literature and extracted the data
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Zheng, Dan-Dan, Dan Duan, and Yu-Qi Cao. "The Best-Evidence of Cluster Nursing Prevention Strategies for Perioperative Venous Thrombosis in Patients with Gynecological Cancer." Global Journal of Medicine 05, no. 01 (2024): 8–20. https://doi.org/10.46633/gjm.050102.

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Objective: To comprehensively retrieve, evaluate, and summarize the best evidence of bundle nursing prevention strategies for perioperative venous thrombosis in patients with gynecological cancer. Methods: The National Guideline Library NGC, the Australian JBI Center for Evidence-based Health Care (JBI EBP), the Scottish InterCollege Guidelines Network (SIGN), the Registered Nurses Association of Ontario (RNAO), and the Canadian Clinical Practice Guidelines Network (CMA) were searched by computer INFOBASE), New Zealand Clinical Practice Guidelines Study Group (NZGG), ClinicalKey for Nursing, T
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Sprenger, Charles. "Judging Experimental Evidence on Dynamic Inconsistency." American Economic Review 105, no. 5 (2015): 280–85. http://dx.doi.org/10.1257/aer.p20151086.

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This article briefly summarizes and judges recent experimental developments exploring the predictions of dynamically inconsistent models. An opinion is provided as to how the literature may evolve given these recent advances.
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Nettleton, Joyce A., Ingeborg A. Brouwer, Ronald P. Mensink, Connie Diekman, and Gerard Hornstra. "Fats in Foods: Current Evidence for Dietary Advice." Annals of Nutrition and Metabolism 72, no. 3 (2018): 248–54. http://dx.doi.org/10.1159/000488006.

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Current discussion of the importance of food fats in the risk of coronary heart disease (CHD) often suffers from preconceptions, misunderstandings, insufficient knowledge, and selective reasoning. As a result, the sustained controversy about dietary fat recommendations can be contradictory and confusing. To clarify some of these issues, the International Expert Movement to Improve Dietary Fat Quality in cooperation with the International Union of Nutritional Sciences (IUNS) organized a symposium at the 21st meeting of the IUNS, October 17, 2017, Buenos Aires, Argentina, to summarize the key sc
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D'Mello, Anila M., and John D. E. Gabrieli. "Cognitive Neuroscience of Dyslexia." Language, Speech, and Hearing Services in Schools 49, no. 4 (2018): 798–809. http://dx.doi.org/10.1044/2018_lshss-dyslc-18-0020.

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Purpose This review summarizes what is known about the structural and functional brain bases of dyslexia. Method We review the current literature on structural and functional brain differences in dyslexia. This includes evidence about differences in gray matter anatomy, white matter connectivity, and functional activations in response to print and language. We also summarize findings concerning brain plasticity in response to interventions. Results We highlight evidence relating brain function and structure to instructional issues such as diagnosis and prognosis. We also highlight evidence abo
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Andreev, D. N., and I. V. Maev. "Rebamipide: evidence base for use in gastroenterology." Terapevticheskii arkhiv 92, no. 12 (2020): 97–104. http://dx.doi.org/10.26442/00403660.2020.12.200455.

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Rebamipide is a cytoprotective drug that has been used in practical gastroenterology for 30 years. This article summarizes the main results of the most relevant clinical studies of rebamipide in diseases of various parts of the gastrointestinal tract, including the esophagus, stomach, small and large intestine.
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Kovács, Gábor László, Judit Dénes, Erika Hubina, László Kovács, Sándor Czirják, and Miklós Góth. "Consensus on the change of criteria for cure of acromegaly during the last decade." Orvosi Hetilap 152, no. 18 (2011): 703–8. http://dx.doi.org/10.1556/oh.2011.29092.

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The Acromegaly Consensus Group redefined the consensus criteria for cure of acromegaly. 74 neurosurgeons and experienced endocrinologists summarized the latest results on diagnosis and treatment of acromegaly. In this consensus statement the reliable growth hormone and insulin-like growth factor-1 assays were established. Definition of disease control was discussed based on the available publications and evidence. This short communication summarizes the clinical aspects of consensus criteria for diagnosis and cure of acromegaly based on the original article. Orv. Hetil., 2011, 152, 703–708.
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Offenbacher, S., J. G. Collins, and P. A. Heasman. "Diagnostic Potential of Host Response Mediators." Advances in Dental Research 7, no. 2 (1993): 175–81. http://dx.doi.org/10.1177/08959374930070020801.

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This review summarizes the data which relate the validation and application of host response markers as diagnostic tests forperiodontal diseases. Practical considerations regarding the general application and evaluation of a diagnostic test for periodontal disease are presented. Experiments which have documented the performance of host response markers as diagnostic measures of disease activity in terms of sensitivity, specificity, and predictive values are summarized. Particular emphasis is placed on the diagnostic potential of gingival crevicular fluid (GCF) components. The considerable body
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Den Hartogh, Danja J., Alessandra Gabriel, and Evangelia Tsiani. "Antidiabetic Properties of Curcumin I: Evidence from In Vitro Studies." Nutrients 12, no. 1 (2020): 118. http://dx.doi.org/10.3390/nu12010118.

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Type 2 diabetes mellitus (T2DM) is a growing metabolic disease characterized by insulin resistance and hyperglycemia. Current preventative and treatment strategies for T2DM and insulin resistance lack in efficacy resulting in the need for new approaches to prevent and manage/treat the disease better. In recent years, epidemiological studies have suggested that diets rich in fruits and vegetables have beneficial health effects including protection against insulin resistance and T2DM. Curcumin, a polyphenol found in turmeric, and curcuminoids have been reported to have antioxidant, anti-inflamma
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Sinnott-Armstrong, Walter, Adina Roskies, Teneille Brown, and Emily Murphy. "Brain Images as Legal Evidence." Episteme 5, no. 3 (2008): 359–73. http://dx.doi.org/10.3366/e1742360008000452.

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ABSTRACTThis paper explores whether brain images may be admitted as evidence in criminal trials under Federal Rule of Evidence 403, which weighs probative value against the danger of being prejudicial, confusing, or misleading to fact finders. The paper summarizes and evaluates recent empirical research relevant to these issues. We argue that currently the probative value of neuroimages for criminal responsibility is minimal, and there is some evidence of their potential to be prejudicial or misleading. We also propose experiments that will directly assess how jurors are influenced by brain im
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Biagi, J. J., and E. A. Eisenhauer. "Systemic treatment policies in ovarian cancer: the next 10 years." International Journal of Gynecologic Cancer 13, Suppl 2 (2003): 231–40. http://dx.doi.org/10.1136/ijgc-00009577-200311001-00017.

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Over the past two decades, the development of treatment policies and practice standards has become formalized. In ovarian cancer, most attention has been focused on the development of policies for front-line systemic treatment, using survival as the major outcome that should drive change. This review summarizes the evidence that supported the emergence of paclitaxel–carboplatin as a widely used standard of care for front-line therapy and some of the contradictory data from randomized studies. Furthermore, recently completed or ongoing randomized studies of the addition of a third cytotoxic age
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Casares, Jorge. "Observational evidence for stellar-mass black holes." Proceedings of the International Astronomical Union 2, S238 (2006): 3–12. http://dx.doi.org/10.1017/s1743921307004590.

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AbstractRadial velocity studies of X-ray binaries provide the most solid evidence for the existence of stellar-mass black holes. We currently have 20 confirmed cases, with dynamical masses in excess of 3 M⊙. Accurate masses have been obtained for a subset of systems which gives us a hint at the mass spectrum of the black hole population. This review summarizes the history of black hole discoveries and presents the latest results in the field.
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Bohn, Torsten, Sascha Rohn, Volker Böhm, et al. "Vitamin A5: Evidence, Definitions, Gaps, and Future Directions." Nutrients 17, no. 14 (2025): 2317. https://doi.org/10.3390/nu17142317.

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With the emergence of a new vitamin concept—vitamin A5—it is essential to first clarify the basic definition of vitamins, particularly vitamin A. This article summarizes the foundational concepts and definitions of vitamins with particular relevance to the discovery, establishment, and categorization of new vitamin concepts. Vitamin A5 was discovered 80 years after the last vitamin was identified. It serves as an umbrella term for the dietary precursors 9-cis-β,β-carotene and 9-cis-13,14-dihydroretinol for the endogenous activator of the nuclear hormone receptor RXR, 9-cis-13,14-dihydroretinoi
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14

Kidwell, Susan M., and Anna K. Behrensmeyer. "Summary: Estimates of Time-Averaging." Short Courses in Paleontology 6 (1993): 301–2. http://dx.doi.org/10.1017/s2475263000001161.

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Figure 1 summarizes estimates for the time-scales over which fossil assemblages accumulate, based on the findings summarized by the various authors of this volume, and organized according to major taxonomic groups in terrestrial and marine environments. For each group, actualistic estimates are based primarily on field evidence for the durability of organic remains, either from time-lapse tracking of carcasses or from direct-dating of individuals in Recent death assemblages; other methods include extrapolating from known rates of sediment accumulation and rates and depths of mixing. Estimates
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Yousefi, Seyde Sedighe, Roshanak Mokaberi Nejad, Mojgan Tansaz, Soodabeh Bioos, and Zeinab Hamzehgardeshi. "Preconception Sex Selection in Traditional Persian Medicine: A Review of the Literature." Crescent Journal of Medical and Biological Sciences 9, no. 1 (2020): 3–8. http://dx.doi.org/10.34172/cjmb.2022.02.

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Objectives: This review investigates the existing research with regard to a variety of different suggested methods by traditional Persian medicine (TPM) about the baby’s sex selection. Materials and Methods: A comprehensive scoping review including five stages was conducted to summarize evidence on pre-implantation sex selection in TPM. The research question and relevant studies were identified in stages 1 and 2, respectively. Then, studies were selected and data were charted in stages 3 and 4, and finally, the results were collated, summarized, and reported in stage 5. Results: Accordingly, 7
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Morlan, Richard E. "Current perspectives on the Pleistocene archaeology of eastern Beringia." Quaternary Research 60, no. 1 (2003): 123–32. http://dx.doi.org/10.1016/s0033-5894(03)00070-x.

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AbstractMost recent summaries of eastern Beringian (Alaska and Yukon) archaeology present the Nenana complex, beginning 11,500–12,000 14C yr B.P., as the beginning of the regional archaeological record. Either explicitly or tacitly, these summaries dismiss or ignore a body of older putative evidence of human occupation that may span the late Wisconsin stade and even extend into part of the mid-Wisconsin interstade. This paper summarizes the interpretive problems surrounding the older findings, bringing together data that have accumulated over a period of two decades, in the hope that a coheren
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Maznev, S. V., O. V. Kokin, V. V. Arkhipov, and A. V. Baranskaya. "Modern and Relict Evidence of the Iceberg Scouring at the Bottom of the Barents and Kara Seas." Океанология 63, no. 1 (2023): 95–107. http://dx.doi.org/10.31857/s0030157423010112.

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The article systematizes and summarizes published data on the parameters and distribution areas of modern and relict iceberg scours (or plough marks), as well as on the maximum possible sizes and drift areas of modern icebergs in the Barents and Kara Seas. According to the open-source bathymetric data, for the first time the analysis of “throughput” of the waters in front of modern glaciers was carried out. Based on summarized and established facts, areas of the most likely distribution of modern iceberg effects on the bottom are determined by the method of expert assessment. This work is rele
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Manzi, Pietro, Pietro Barberini, and Fabrizio Dori. "Hospital Based Health Technology Assessment: an example from Siena." Farmeconomia. Health economics and therapeutic pathways 16, no. 1 (2015): 7–13. http://dx.doi.org/10.7175/fe.v16i1.943.

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The Health Technology Assessment (HTA) has emerged in recent years as a useful tool in healthcare decision-making. It is a multidisciplinary process that summarizes information about the medical, social, economic and ethical issues related to the use of a health technology and provides evidence-based information on how to allocate resources. The experience of Siena University Hospital is an example of multidisciplinary hospital-based HTA. In the present paper we summarize the organization of HTA commission and the assessment methodology of the purchase, rental or sale of medical equipment and
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Golden, Isaac. "Homoeoprophylaxis—A Summary of Latest Developments." Homœopathic Links 33, no. 02 (2020): 078–81. http://dx.doi.org/10.1055/s-0040-1709472.

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AbstractThis article (1) reports on a conference in Delhi in January 2020 directed toward building the evidence base of homoeoprophylaxis, (2) summarizes the latest evidence base supporting the effectiveness of homoeoprophylaxis and (3) advises readers of a change in long-term endemic homoeoprophylaxis programme.
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Foote-Lucero, Christine. "AFN Journal Club Winter-Spring Reviews." Journal of the Academy of Forensic Nursing 3, no. 1 (2025): 75–80. https://doi.org/10.29173/jafn865.

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Straus, Murray A. "Thirty Years of Denying the Evidence on Gender Symmetry in Partner Violence: Implications for Prevention and Treatment." Partner Abuse 1, no. 3 (2010): 332–62. http://dx.doi.org/10.1891/1946-6560.1.3.332.

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The first part of this article summarizes results from more than 200 studies that have found gender symmetry in perpetration and in risk factors and motives for physical violence in martial and dating relationships. It also summarizes research that has found that most partner violence is mutual and that self-defense explains only a small percentage of partner violence by either men or women. The second part of the article documents seven methods that have been used to deny, conceal, and distort the evidence on gender symmetry. The third part of the article suggests explanations for the denial
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Dougherty, Shaun M. "Putting evidence on CTE to work." Phi Delta Kappan 104, no. 6 (2023): 6–11. http://dx.doi.org/10.1177/00317217231161520.

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Policy makers have taken more interest in career and technical education (CTE) in recent years, but evidence regarding what kinds of programs produce the most important outcomes is still emerging. Shaun M. Dougherty summarizes what recent research tells us about the impact of these programs. Evidence has shown that CTE-dedicated schools, career academies, and programs linked to workforce needs can improve high school graduation rates and workforce earnings, but research is still emerging on how well CTE programs prepare students for postsecondary education. Most of the recent research has not
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Upaphong, Phit, Chanisa Thonusin, Janejit Choovuthayakorn, Nipon Chattipakorn, and Siriporn C. Chattipakorn. "The Possible Positive Mechanisms of Pirenoxine in Cataract Formation." International Journal of Molecular Sciences 23, no. 16 (2022): 9431. http://dx.doi.org/10.3390/ijms23169431.

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Cataract is the leading cause of blindness worldwide. A diverse range of medication has been invented to prevent or treat cataract. Pirenoxine (PRX), a drug with strong antioxidant properties, has been used topically to treat cataract, and there is much evidence to demonstrate the beneficial effects of PRX on lens opacity from in vitro and in vivo models. In clinical use, PRX has been prescribed worldwide by ophthalmologists for over six decades; however, there is still controversy with regard to its efficacy, and thus PRX remains an off-label use for cataract treatment. This comprehensive rev
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Normann, Amber J., Rebekah L. Wilson, Ellaney Matarese, et al. "Racial Health Disparity and Risk of Multiple Myeloma: Implications for Energy Balance Interventions." Cancer Prevention Research 18, no. 5 (2025): 261–69. https://doi.org/10.1158/1940-6207.capr-24-0199.

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Abstract Established risk factors for multiple myeloma, including obesity and sedentary lifestyles, are associated with well-known racial/ethnic disparities in disease risk. This review examines established risk determinants for multiple myeloma in Black adults, summarizes evidence linking lifestyle factors, including obesity, physical inactivity, and diet, to disease risk, and discusses energy balance interventions, including cultural tailoring, to mitigate multiple myeloma risk. We summarize current evidence for racial/ethnic disparities in risk factors for multiple myeloma, including unmodi
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Davis, Ian, and Sadis Matalon. "Reactive Species in Viral Pneumonitis: Lessons From Animal Models." Physiology 16, no. 4 (2001): 185–90. http://dx.doi.org/10.1152/physiologyonline.2001.16.4.185.

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Recent evidence suggests that pneumonitis induced by many important human viral pathogens may result from exuberant generation of reactive species by inflammatory cells in response to infection. This review summarizes current evidence from animal model studies regarding the beneficial (antiviral) and harmful (tissue-damaging) effects of reactive species for the host.
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Davis, Michael J., Xin Wu, Timothy R. Nurkiewicz, et al. "Integrins and mechanotransduction of the vascular myogenic response." American Journal of Physiology-Heart and Circulatory Physiology 280, no. 4 (2001): H1427—H1433. http://dx.doi.org/10.1152/ajpheart.2001.280.4.h1427.

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This review summarizes what is currently known about the role of integrins in the vascular myogenic response. The myogenic response is the rapid and maintained constriction of a blood vessel in response to pressure elevation. A role for integrins in this process has been suggested because these molecules form an important mechanical link between the extracellular matrix and the vascular smooth muscle cytoskeleton. We briefly summarize evidence for a general role of integrins in mechanotransduction. We then describe the integrin subunit combinations known to exist in smooth muscle and the vascu
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Franklin, Cynthia. "The Future of School Social Work Practice: Current Trends and Opportunities." Advances in Social Work 6, no. 1 (2005): 167–81. http://dx.doi.org/10.18060/89.

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This article discusses the information on school social work practice in the United States and summarizes recent trends and their implications for the future of school social work. The number of school social workers and current infrastructure available for the development of school social work practice is reviewed. Five sociocultural trends are summarized that are affecting public schools as well as important school-based practice trends such as standardized testing, and high stakes accountability measures. The emerging practice trend of evidence-based practices is discussed in light of its s
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Lam, Edwin, Yi Ting (Kayla) Lien, Water K. Kraft, et al. "Vancomycin in peritoneal dialysis: Clinical pharmacology considerations in therapy." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 40, no. 4 (2020): 384–93. http://dx.doi.org/10.1177/0896860819889774.

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Intraperitoneal vancomycin is the first-line therapy in the management of peritoneal dialysis (PD)-related peritonitis. However, due to the paucity of data, vancomycin dosing for peritonitis in patients on automated peritoneal dialysis (APD) is empiric and based on clinical experience rather than evidence. Studies in continuous ambulatory peritoneal dialysis (CAPD) patients have been used to provide guidelines for dosing and are often extrapolated for APD use, but it is unclear whether this is appropriate. This review summarizes the available pharmacokinetic data used to inform optimal dosing
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Schmidt, Peter C., Gabriela Ruchelli, Sean C. Mackey, and Ian R. Carroll. "Perioperative Gabapentinoids." Anesthesiology 119, no. 5 (2013): 1215–21. http://dx.doi.org/10.1097/aln.0b013e3182a9a896.

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Abstract This article summarizes the current evidence for the use of gabapentinoids in the perioperative setting and provides useful clinical recommendations regarding dosing, timing, and choice of agent.
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Nugent, Rachel. "Reflections on Norheim (2018), Disease Control Priorities Third Edition Is Published Comment on "Disease Control Priorities Third Edition Is Published: A Theory of Change Is Needed for Translating Evidence to Health Policy"." International Journal of Health Policy and Management 8, no. 6 (2019): 375–77. http://dx.doi.org/10.15171/ijhpm.2019.09.

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The publication of Disease Control Priorities, 3rd edition (DCP3) is a major milestone in the global health world. DCP3 reviews and summarizes high quality health intervention effectiveness and cost-effectiveness evidence relevant to low- and middle-income countries and is freely available to users. This Commentary summarizes Norheim’s (2018) assessment of DCP3’s role in country health priority-setting and offers reflections on what DCP3 can continue to offer countries seeking to improve their purchasing of health.
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Hsu, Mei-Hsin, Yu-Chieh Chen, Jiunn-Ming Sheen, and Li-Tung Huang. "Maternal Obesity Programs Offspring Development and Resveratrol Potentially Reprograms the Effects of Maternal Obesity." International Journal of Environmental Research and Public Health 17, no. 5 (2020): 1610. http://dx.doi.org/10.3390/ijerph17051610.

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Maternal obesity during pregnancy is a now a public health burden that may be the culprit underlying the ever-increasing rates of adult obesity worldwide. Understanding the association between maternal obesity and adult offspring’s obesity would inform policy and practice regarding offspring health through available resources and interventions. This review first summarizes the programming effects of maternal obesity and discusses the possible underlying mechanisms. We then summarize the current evidence suggesting that maternal consumption of resveratrol is helpful in maternal obesity and alle
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Malaipun, Sarayut, Pongsakorn Surin, Wiwat Singsai, and Wichai Chattinnawat. "Clustering Production and Operational Practices of SME Using Correspondence Analysis: A Case Study of Northern OTOP Thailand." International Journal of Global Optimization and Its Application 1, no. 3 (2022): 145–61. http://dx.doi.org/10.56225/ijgoia.v1i3.65.

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This study aims to identify the actual conditions of the current operational practices of the One Tambon One Product (OTOP) and the actual sales and income. This research summarizes and classifies the existing practices concerning different groups of OTOP products and presents empirical evidence on how and what practices correspond to the actual business performance. This research adopted correspondence analysis as a data analysis and visualization tool to summarize and present if clusters or relationships exist among categorical variables of OTOP groups, operation practices and their revenue
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Larach, Daniel B., Jennifer M. Hah, and Chad M. Brummett. "Perioperative Opioids, the Opioid Crisis, and the Anesthesiologist." Anesthesiology 136, no. 4 (2022): 594–608. http://dx.doi.org/10.1097/aln.0000000000004109.

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This review summarizes current evidence related to perioperative opioid prescription fulfillment and use and discusses the role of personalized anesthesia care in mitigating opioid-related harms without compromising analgesia.
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Menten, Karl M. "Jets and Outflows from Massive Protostars." Highlights of Astronomy 12 (2002): 153–55. http://dx.doi.org/10.1017/s1539299600013113.

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AbstractMolecular outflows are found in most regions of massive star formation. However, evidence for highly collimated jets from massive protostars is still elusive. This paper briefly summarizes the observational status.
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Moser, Petra. "Patents and Innovation: Evidence from Economic History." Journal of Economic Perspectives 27, no. 1 (2013): 23–44. http://dx.doi.org/10.1257/jep.27.1.23.

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What is the optimal system of intellectual property rights to encourage innovation? Empirical evidence from economic history can help to inform important policy questions that have been difficult to answer with modern data: For example, does the existence of strong patent laws encourage innovation? What proportion of innovations is patented? Is this share constant across industries and over time? How does patenting affect the diffusion of knowledge? How effective are prominent mechanisms, such as patent pools and compulsory licensing, that have been proposed to address problems with the patent
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Stookey, Jodi D., and Stavros A. Kavouras. "Water Researchers Do Not Have a Strategic Plan for Gathering Evidence to Inform Water Intake Recommendations to Prevent Chronic Disease." Nutrients 12, no. 11 (2020): 3359. http://dx.doi.org/10.3390/nu12113359.

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Confusion has persisted for decades in the United States (U.S.) over how much plain water to drink, despite national water intake recommendations which are based on high quality scientific evidence. This editorial summarizes the definition, alignment and coordination of evidence that informs the current U.S. adequate intake (AI) recommendations for water. It highlights gaps in the evidence that perpetuate confusion and opportunity to address the gaps through strategic planning.
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Chande, Nilesh, Samuel P. Costello, Berkeley N. Limketkai, et al. "Alternative and Complementary Approaches for the Treatment of Inflammatory Bowel Disease: Evidence From Cochrane Reviews." Inflammatory Bowel Diseases 26, no. 6 (2019): 843–51. http://dx.doi.org/10.1093/ibd/izz223.

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The Cochrane IBD Group presented a symposium at Digestive Diseases Week 2018 entitled “Alternative and Complementary Approaches for the Treatment of IBD: Evidence from Cochrane Reviews.” This article summarizes the data presented at this symposium.
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Chavarría-Bolaños DDS, MSc, PhD, Daniel, and Vicente Esparza-Villalpando DDS, MSc. "Preventive Analgesia: An Evidence-Based Alternative for Dentistry." Odovtos - International Journal of Dental Sciences 19, no. 2 (2017): 10. http://dx.doi.org/10.15517/ijds.v19i2.28143.

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The effective management of pain in dentistry increases the patient satisfaction, improves the treatment outcome and reduces the cost of care. To achieve this goal, different strategies are available for the administration of analgesics, such as preventive analgesia. The aim of this approach is to minimize sensitization induced by noxious perioperatory stimuli (both pre, intra and postoperatory). Available research support the favorable effect of preventive analgesia, although it also recognizes an important lack of high quality evidence to confirm its advantages. This new perspective article
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Chopra, Supriya, Nilesh Ranjan, and Prachi Mittal. "Postoperative adjuvant radiation for cervix cancer: reflections on the evidence and a peep into the future." International Journal of Gynecologic Cancer 32, no. 3 (2022): 225–30. http://dx.doi.org/10.1136/ijgc-2021-002528.

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Early stage cervical cancer, stages IB1–2 and IIA1, can be treated with (chemo)radiation and brachytherapy or radical hysterectomy with or without further adjuvant (chemo)radiation. In a carefully selected cohort for surgery, traditionally a small proportion of patients would need adjuvant (chemo)radiation so that the therapeutic ratio is maximized. However, advances in radiation technology, specifically intensity modulated radiotherapy, have led to a reduction in treatment related adverse events. Also, recent developments in risk stratification suggest using a lower threshold to offer adjuvan
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Murray-Swank, Aaron B., and Lisa Dixon. "Family Psychoeducation as an Evidence-Based Practice." CNS Spectrums 9, no. 12 (2004): 905–12. http://dx.doi.org/10.1017/s109285290000972x.

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AbstractFamily psychoeducation programs have emerged as a strongly supported evidence-based practice in the treatment of schizophrenia and bipolar disorder. Over 30 randomized clinical trials demonstrated that psychoeducation programs reduce relapse, improve symptomatic recovery, and enhance psychosocial and family outcomes. Recent work supports family psychoeducation strategies for other disorders, including major depression, obsessive-compulsive disorder, and borderline personality disorder. This review summarizes the research evidence supporting prominent models of family psychoeducation. P
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El-Sewify, Islam M., Ahmed Radwan, Nehal H. Elghazawy, Wolfgang Fritzsche, and Hassan M. E. Azzazy. "Optical chemosensors for environmental monitoring of toxic metals related to Alzheimer's disease." RSC Advances 12, no. 50 (2022): 32744–55. http://dx.doi.org/10.1039/d2ra05384e.

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This review briefly summarizes evidence that links toxic metals to onset and progression of Alzheimer's disease. It discusses the structure and fabrication of optical chemosensors, and their use for monitoring toxic metals in water.
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Tullo, Ellen, Julia Newton, and Alison Clapp. "What can e-learning offer geriatric medicine in the UK?" Reviews in Clinical Gerontology 22, no. 3 (2012): 235–42. http://dx.doi.org/10.1017/s0959259812000081.

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SummaryThe expansion of e-learning in medical education is a reflection of the inherent advantages that technology can bring to teaching and learning. Geriatric medicine has taken advantage of some of the benefits associated with e-learning in terms of undergraduate education, specialty training and interdisciplinary training. However, there are further opportunities and challenges to be met for geriatric medicine to make the very most of e-learning. This review outlines the terminology associated with e-learning, summarizes the advantages and potential problems, and considers the evidence bas
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Cuttica, Carla Micaela, Irene Maria Briata, and Andrea DeCensi. "Novel Treatments for Obesity: Implications for Cancer Prevention and Treatment." Nutrients 15, no. 17 (2023): 3737. http://dx.doi.org/10.3390/nu15173737.

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It is now established that obesity is related to a higher incidence of cancer during a lifespan. The effective treatment of obesity opens up new perspectives in the treatment of a relevant modifiable cancer risk factor. The present narrative review summarizes the correlations between weight loss in obesity and cancer. The current knowledge between obesity treatment and cancer was explored, highlighting the greatest potential for its use in the treatment of cancer in the clinical setting. Evidence for the effects of obesity therapy on proliferation, apoptosis, and response to chemotherapy is su
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Parratt, James R., Agnes Vegh, and Julius Gy Papp. "Bradykinin as an endogenous myocardial protective substance with particular reference to ischemic preconditioning–a brief review of the evidence." Canadian Journal of Physiology and Pharmacology 73, no. 7 (1995): 837–42. http://dx.doi.org/10.1139/y95-114.

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The present brief review summarizes the evidence for the possibility that endogenously released bradykinin plays a major role in protecting the heart against the consequences of acute myocardial injury. This evidence includes the facts that kinins are generated under myocardial ischemia; that when they are administered, they are cardioprotective (e.g., antiarrhythmic); that drugs that enhance the release of bradykinin from the ischemic heart reduce the ischemic injury and, conversely, drugs that block bradykinin receptors attenuate the reduction in ischemic injury resulting from the release of
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Goncharova, N., and O. M. Moiseeva. "Ramipril therapy in the framework of evidence-based medicine." "Arterial’naya Gipertenziya" ("Arterial Hypertension") 15, no. 2 (2009): 242–45. http://dx.doi.org/10.18705/1607-419x-2009-15-2-242-245.

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The article summarizes the available data on ramipril in hypertensive patients of high cardiovascular risk. The results of studies demonstrate strong and long-lasting antihypertensive effect of ramipril. Moreover, ramipril treatment decreases cardiovascular events rate, damage of target organs, atherosclerosis progression and new cases of diabetes mellitus. The treatment by ramipril represents vasculoprotective and renoprotective effects in diabetes patients. Possible antiarrhythmic activity of ramipril is of particular interest in atrial fi brillation. Ramipril shows both high effi cacy and l
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Perfilyev, V. Yu, A. G. Miroshnichenko, V. A. Zhelev, and E. V. Devald. "Alternative anticonvulsants in neonatology." Voprosy praktičeskoj pediatrii 17, no. 4 (2022): 76–83. http://dx.doi.org/10.20953/1817-7646-2022-4-76-83.

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The approaches to pharmacotherapy of neonatal seizures are always empirical and vary across the globe. There is still no consensus on this issue because of the highly variable efficacy of anticonvulsants traditionally used in newborns. Currently, none of these drugs has sufficient evidence to make an unambiguous conclusion on their efficacy and safety. Therefore, the search for new anticonvulsants for newborns is highly relevant. This review aims to summarize existing literature surrounding anticonvulsants that can potentially be used in newborns. It discusses advantages and disadvantages, as
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Mourad, Sophia N., Cynthia De la Garza-Ramos, and Beau B. Toskich. "Radiation Segmentectomy for the Treatment of Hepatocellular Carcinoma: A Practical Review of Evidence." Cancers 16, no. 3 (2024): 669. http://dx.doi.org/10.3390/cancers16030669.

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Radiation segmentectomy is a versatile, safe, and effective ablative therapy for early-stage hepatocellular carcinoma. Advances in radiation segmentectomy patient selection, procedural technique, and dosimetry have positioned this modality as a curative-intent and guideline-supported treatment for patients with solitary HCC. This review describes key radiation segmentectomy concepts and summarizes the existing literary knowledgebase.
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Mallet, Robert T., Albert H. Olivencia-Yurvati, and Rolf Bünger. "Pyruvate-enriched resuscitation for shock." Experimental Biology and Medicine 243, no. 8 (2018): 663–64. http://dx.doi.org/10.1177/1535370218773717.

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This commentary addresses the recent retraction of an article which reported favorable outcomes in septic patients treated with intravenous pyruvate. The retracted report was cited in the authors’ recent minireview on the cellular mechanisms and clinical application of pyruvate to improve cardiac performance. Because the retracted article reports pyruvate-enhanced resuscitation of critically ill patients, the authors wish to inform the readership, especially critical care providers, that this particular clinical application of pyruvate is not now supported by robust evidence. After discussing
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Houtchens, Maria K., Lauren B. Zapata, Kathryn M. Curtis, and Maura K. Whiteman. "Contraception for women with multiple sclerosis: Guidance for healthcare providers." Multiple Sclerosis Journal 23, no. 6 (2017): 757–64. http://dx.doi.org/10.1177/1352458517701314.

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Family planning is essential for any comprehensive treatment plan for women of reproductive age with multiple sclerosis (MS), including counseling on using effective contraception to optimally time desired and prevent unintended pregnancies. This topical review summarizes the first evidence-based recommendations on contraception safety for women with MS. In 2016, evidence-based recommendations for contraceptive use by women with MS were included in US Medical Eligibility Criteria for Contraceptive Use. They were developed after review of published scientific evidence on contraception safety an
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Li, Kexuan, Xiuyue Qiu, Jiayu Zhang, Yingshuyi Zhou, and Youfen Fan. "Best evidence summary for preventing and preventing epidermal growth factor receptor inhibitors induced paronychia in cancer patients." Frontiers in Oncology 15 (April 14, 2025). https://doi.org/10.3389/fonc.2025.1555114.

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ObjectiveTo evaluate and summarize the best evidence for preventing and managing epidermal growth factor receptor inhibitors induced paronychia in cancer patients. It aims to provide a reference for medical staff.MethodsWe systematically searched for evidence on paronychia symptoms in 14 databases such as Cnki、Wanfang, 7 guide websites such as GIN and NZGG, and 8 professional websites such as UICC and ACS from database establishment to August 2024. Two researchers evaluated the quality of the literature and extracted the data.ResultsA total of 20 articles were included in this study, including
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