Academic literature on the topic 'SUMO SITES PREDICTION'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'SUMO SITES PREDICTION.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "SUMO SITES PREDICTION"

1

Sharma, Dolly, Anu Kumari, Manisha Kumari, and Ramesh C. Meena. "SUMO Sites Prediction in Human Transcription Factors Involved in Hypoxia induced Cardiac Illnesses." Defence Life Science Journal 9, no. 1 (2024): 44–54. http://dx.doi.org/10.14429/dlsj.9.19455.

Full text
Abstract:
Protein SUMOylation is a reversible and well knownpost-translational modificationprocess of the cells. It may change a protein's cellular location, interactions, and possible structural shape before it develops to carry out its basic functions.Also, it decides the binding of transcription factors and DNA binding proteins tochromatin in addition to various cis and trans regulatory factors. Alterations in protein SUMOylation have been linked with a variety of disorders and developmental anomalies.Tentative approaches to identify SUMO binding sites are challenging due todynamic nature of the SUMO
APA, Harvard, Vancouver, ISO, and other styles
2

Zhao, Qi, Yubin Xie, Yueyuan Zheng, et al. "GPS-SUMO: a tool for the prediction of sumoylation sites and SUMO-interaction motifs." Nucleic Acids Research 42, W1 (2014): W325—W330. http://dx.doi.org/10.1093/nar/gku383.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Ijaz, Amna. "SUMOhunt: Combining Spatial Staging between Lysine and SUMO with Random Forests to Predict SUMOylation." ISRN Bioinformatics 2013 (June 17, 2013): 1–11. http://dx.doi.org/10.1155/2013/671269.

Full text
Abstract:
Modification with SUMO protein has many key roles in eukaryotic systems which renders the identification of its target proteins and sites of considerable importance. Information regarding the SUMOylation of a protein may tell us about its subcellular localization, function, and spatial orientation. This modification occurs at particular and not all lysine residues in a given protein. In competition with biochemical means of modified-site recognition, computational methods are strong contenders in the prediction of SUMOylation-undergoing sites on proteins. In this research, physicochemical prop
APA, Harvard, Vancouver, ISO, and other styles
4

Khan, Salman, Mukhtaj Khan, Nadeem Iqbal, Naqqash Dilshad, Maram Fahaad Almufareh, and Najah Alsubaie. "Enhancing Sumoylation Site Prediction: A Deep Neural Network with Discriminative Features." Life 13, no. 11 (2023): 2153. http://dx.doi.org/10.3390/life13112153.

Full text
Abstract:
Sumoylation is a post-translation modification (PTM) mechanism that involves many critical biological processes, such as gene expression, localizing and stabilizing proteins, and replicating the genome. Moreover, sumoylation sites are associated with different diseases, including Parkinson’s and Alzheimer’s. Due to its vital role in the biological process, identifying sumoylation sites in proteins is significant for monitoring protein functions and discovering multiple diseases. Therefore, in the literature, several computational models utilizing conventional ML methods have been introduced to
APA, Harvard, Vancouver, ISO, and other styles
5

Lee, Choong-Eun, Tam Tran, Seol-Hee Kim, Ki-Sa Sung, and Cheol-Yong Choi. "Regulation of IL-4-induced STAT6 activation by SUMOylation (P6307)." Journal of Immunology 190, no. 1_Supplement (2013): 184.15. http://dx.doi.org/10.4049/jimmunol.190.supp.184.15.

Full text
Abstract:
Abstract As a key signaling molecule in the cytokine-mediated transcriptional activation STATs are shown to undergo PTMs including phosphorylation, acetylation, methylation, ubiquitination and SUMOylation. The SUMO-modification of STAT1 has been implicated in the regulation of protein stability, nuclear translocation, and transcriptional activation, probably through the reduction of the formation and life-span of the active dimer. As a part of regulation of IL-4 signaling mechanism, we have investigated the role of SUMOylation on STAT6 activation. We have identified potential SUMOylation sites
APA, Harvard, Vancouver, ISO, and other styles
6

Yu, Jian, Jianping Lan, Yuanyuan Zhu, Xiaoyu Lai, and He Huang. "Sumoylation of TRF1 Is Essential for Its Recruitment to ALT-Associated PML Bodies." Blood 110, no. 11 (2007): 4169. http://dx.doi.org/10.1182/blood.v110.11.4169.4169.

Full text
Abstract:
Abstract To achieve unlimited proliferative potential, most cancer cells activate telomerase to maintain telomeres. However, some cancer cells elongate telomeres through a telomerase-independent pathway termed alternative lengthening of telomeres (ALT). These ALT cells contain a novel promyelocytic leukemia (PML) body (ALT-associated PML body, APB), which comprises telomeric DNA and a number of proteins, including PML protein, the telomere binding proteins TRF1 and TRF2, replication factor A, and recombination factors Rad51, Rad52, and the Rad50/Mre11/NBS1 complex. TRF1, as the first identifie
APA, Harvard, Vancouver, ISO, and other styles
7

Qian, Ying, Shasha Ye, Yu Zhang, and Jiongmin Zhang. "SUMO-Forest: A Cascade Forest based method for the prediction of SUMOylation sites on imbalanced data." Gene 741 (May 2020): 144536. http://dx.doi.org/10.1016/j.gene.2020.144536.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Liu, Yan, Zhenhua Zheng, Bo Shu, et al. "SUMO Modification Stabilizes Enterovirus 71 Polymerase 3D To Facilitate Viral Replication." Journal of Virology 90, no. 23 (2016): 10472–85. http://dx.doi.org/10.1128/jvi.01756-16.

Full text
Abstract:
ABSTRACT Accumulating evidence suggests that viruses hijack cellular proteins to circumvent the host immune system. Ubiquitination and SUMOylation are extensively studied posttranslational modifications (PTMs) that play critical roles in diverse biological processes. Cross talk between ubiquitination and SUMOylation of both host and viral proteins has been reported to result in distinct functional consequences. Enterovirus 71 (EV71), an RNA virus belonging to the family Picornaviridae , is a common cause of hand, foot, and mouth disease. Little is known concerning how host PTM systems interact
APA, Harvard, Vancouver, ISO, and other styles
9

Fang, Zhou, Yun Deng, Haihong Wang, and Jun Zhou. "SUMOylation of zebrafish transcription factor Zbtb21 affects its transcription activity." PeerJ 12 (April 22, 2024): e17234. http://dx.doi.org/10.7717/peerj.17234.

Full text
Abstract:
Background Post-translational modification by Small Ubiquitin-like MOdifier (SUMO) is an important mechanism to regulate protein activity, protein stability, and localization of substrates. Zbtb21 is a zinc finger and BTB (Broad-complex, Tram-track and Bric à brac) domain-containing transcription factor. Bioinformatic prediction suggests several putative SUMOylated sites in Zbtb21 protein. Methods Two evolutionarily conserved lysine residues in Zbtb21 protein were mutated alone or in combination to disrupt the binding with SUMO molecules. Western blot and co-immunoprecipitation analyses were p
APA, Harvard, Vancouver, ISO, and other styles
10

Liu, Boshu, Sujun Li, Yinglin Wang, Lin Lu, Yixue Li, and Yudong Cai. "Predicting the protein SUMO modification sites based on Properties Sequential Forward Selection (PSFS)." Biochemical and Biophysical Research Communications 358, no. 1 (2007): 136–39. http://dx.doi.org/10.1016/j.bbrc.2007.04.097.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "SUMO SITES PREDICTION"

1

TOMAR, RAVI KUMAR. "STUDY OF SMALL UBIQUITININ LOKE MODIFIERS AND CHAPERONIC SIGNALING IN NON-INSULIN DEPENDENT DIABETES MELLITUS." Thesis, 2016. http://dspace.dtu.ac.in:8080/jspui/handle/repository/14955.

Full text
Abstract:
Small ubiquitin-related modifier (SUMO) family proteins function inpost-translational modifications of proteinsby covalently attaching to them. This helps in modification of many proteins involve in diverse cellular processes, like nuclear transport, transcriptional regulation, signal transduction andmaintenance of genome integrity. An enzyme pathway which is related to the ubiquitin pathway control theattachment between SUMO and proteins. Heat shock protein 27 (HSP27) helps stressed cells to survive in adverse conditions by accumulating in them. HSP27 function in the ubiquitination process
APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "SUMO SITES PREDICTION"

1

Omer J R. "Modelling the effects of dewatering on pile settlement by integrating finite element and load-transfer analyses." In Information Technology in Geo-Engineering. IOS Press, 2010. https://doi.org/10.3233/978-1-60750-617-1-528.

Full text
Abstract:
A Windows based tool is developed for integrating a finite element (FE) model for ground water lowering with a load-transfer method, for use in predicting negative skin friction and settlement of pile foundations influenced by well pumping. Computed results from a finite element analysis are automatically transferred to spreadsheet files, which are linked to a purpose-written program for pile load-transfer analysis. The program is specially interfaced to capture electronic site investigation data from in-situ tests, which may be supplemented by manually entered data from laboratory soil tests.
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "SUMO SITES PREDICTION"

1

Alajmei, Shabeeb. "Prediction of Proppant Distribution in a Horizontal Hydraulic Fracturing Stage." In GOTECH. SPE, 2025. https://doi.org/10.2118/224473-ms.

Full text
Abstract:
Abstract Distributing the injected proppant equally between different perforated clusters remains challenging and requires optimization to achieve effective stimulation treatments. The distribution of proppant is essential to sustain the induced fracture conductivity and maximize the productivity of the stimulated well. Several factors affect proppant distribution and placement in different perforation clusters, including injection rate, proppant concentration, and fluid viscosity. Field proppant distribution data from a single stage, containing 15 clusters and 21 clusters, were used. The comp
APA, Harvard, Vancouver, ISO, and other styles
2

Wang, Bo, Banglin Liu, Yong-Yi Wang, Alex Wang, and Steve Rapp. "Burst Pressure Prediction of Pipes With SCC Colonies: Development of Intelligent Flaw Interaction Rules." In 2020 13th International Pipeline Conference. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/ipc2020-9693.

Full text
Abstract:
Abstract Stress Corrosion Cracking (SCC) often occurs in clusters or colonies containing anywhere from a few cracks to hundreds of individual cracks. Multiple closely spaced cracks may interact, resulting in a burst pressure lower than what might be expected from a single crack. Most existing flaw interaction rules account for these interactions by using a single interacting crack to represent multiple cracks when the separations between them are less than a critical spacing. The length of this interacting crack is usually the sum of the individual crack length plus the spacing between them. U
APA, Harvard, Vancouver, ISO, and other styles
3

Ma, L., A. S. Kobayashi, S. N. Atluri, and P. W. Tan. "Crack Linkup at Multiple Site Damage." In ASME 1998 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1998. http://dx.doi.org/10.1115/imece1998-0354.

Full text
Abstract:
Abstract A commonly used design criterion for predicting the onset of crack link up at a multiple site damage (MSD) is when the sum of the plastic zones of two adjacent cracks is equal to the remaining ligament (Swift 1985, Broek et al 1994). The collapse load predicted by this criterion, however, will differ with the analytical plastic zone and in general, will yield a nonconservative load. Recently, Pyo et al (1997) have shown that the T* integral, which was designed for elastic-plastic fracture mechanics, can predict the extent of stable crack growth and the subsequent collapse load of wide
APA, Harvard, Vancouver, ISO, and other styles
4

Matoušek, Václav, Robert Visintainer, John Furlan, and Anders Sellgren. "Frictional Head Loss of Various Bimodal Settling Slurry Flows in Pipe." In ASME-JSME-KSME 2019 8th Joint Fluids Engineering Conference. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/ajkfluids2019-5395.

Full text
Abstract:
Abstract Pipe flows of bimodal settling slurries exhibit frictional head losses quite different from those determined simply as a sum of loss contributions by the individual fractions. Mechanisms governing flow friction and resulting from an interaction of grains of different fractions in transported slurry are not well understood. This makes a prediction of the frictional head loss in flows of bimodal slurries with Newtonian carrier uncertain. An extensive experimental campaign was conducted in GIW Hydraulic Laboratory in 2016 with slurries of four narrow graded fractions of the virtually sam
APA, Harvard, Vancouver, ISO, and other styles
5

Acton, M. R., P. J. Baldwin, R. P. Cleaver, and D. J. McCollum. "Methods for Assessing Risks at Above Ground Installations." In 2004 International Pipeline Conference. ASMEDC, 2004. http://dx.doi.org/10.1115/ipc2004-0573.

Full text
Abstract:
This paper describes a package of computer models that has been developed to assess the risks from gas releases at above ground installations associated with natural gas transmission pipelines. The package can be applied to compressor stations (containing compressor enclosures and associated gas treatment equipment) and pressure reduction stations, through to single block valve installations. It has been designed for used by safety engineers in performing quantified risk and hazard analysis, as required to meet regulatory requirements, such as the COMAH Regulations or the DSEAR Regulations in
APA, Harvard, Vancouver, ISO, and other styles
6

Niccolini Marmont Du Haut Champ, Carlo Alberto, Mario Luigi Ferrari, Paolo Silvestri, and Aristide Fausto Massardo. "Signal Processing Techniques to Detect Centrifugal Compressors Instabilities in Large Volume Power Plants." In ASME Turbo Expo 2020: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/gt2020-14795.

Full text
Abstract:
Abstract The present paper shows signal processing techniques applied to experimental data obtained from a T100 microturbine connected with different volume sizes. This experimental activity was conducted by means of the test rig developed at the University of Genoa for hybrid systems emulation. However, these results can be extended to all advanced cycles in which a microturbine is connected with additional external components which lead to an increase of the plant volume size. Since in this case a 100 kW microturbine was used, the volume was located between the heat recovery unit outlet and
APA, Harvard, Vancouver, ISO, and other styles
7

Hsu, L. L. "Total Corrosion Control for Industrial Gas Turbines: Airborne Contaminants and Their Impact on Air/Fuel/Water Management." In ASME 1988 International Gas Turbine and Aeroengine Congress and Exposition. American Society of Mechanical Engineers, 1988. http://dx.doi.org/10.1115/88-gt-65.

Full text
Abstract:
Turbine longevity in the field is determined by the extent of its operation within design limits under mechanical and thermal loads as well as the environmental effects that undermine material properties on component surfaces. It is standard practice for the original equipment manufacturer (OEM) to specify maximum concentrations of harmful contaminants in the fuel for corrosion control. Some manufacturers have deployed on-line, in-service monitoring systems designed to incorporate data, such as temperature, speeds and start-stop cycles, into a functional, quasi-empirical equation, with an envi
APA, Harvard, Vancouver, ISO, and other styles
8

Agranat, Vladimir M., Sergei V. Zhubrin, and Igor Pioro. "Multi-Group Two-Phase Flow Model of Drift Drop Plume." In 2014 22nd International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/icone22-30010.

Full text
Abstract:
A homogeneous two-phase multi-group model of drift drop plumes emerging from natural draft cooling towers has been developed and validated using the experimental data obtained in the 1977 Chalk Point Dye Tracer Experiment (CPDTE). The conservation equations for mass fractions of water droplets having different sizes are solved in addition to the standard conservation equations for mixture mass, momentum, energy, water vapor mass fraction and turbulent quantities (turbulent kinetic energy and its dissipation rate). Extra terms are provided to the conservation equations for mass fractions of liq
APA, Harvard, Vancouver, ISO, and other styles
9

Gill, Peter, Peter Brown, David Tice, Norman Platts, and Chris Currie. "Fatigue Initiation of 304L Stainless Steel Subject to Thermal Shock Loading in a PWR Environment." In ASME 2019 Pressure Vessels & Piping Conference. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/pvp2019-93923.

Full text
Abstract:
Abstract The evaluation procedures for fatigue initiation of nuclear class 1 components are defined in ASME BPVC Section III NB-3200 (Design by Analysis) and NB-3600 (Piping Design). Design fatigue curves are provided to establish the suitability of a component for cyclic service and define the allowable number of cycles as a function of applied stress amplitude (S-N curves). The number of load cycles at a particular strain range is then divided by the cycles to failure to obtain a partial usage factor., and the cumulative usage factor (CUF) for the component site, calculated from the sum of t
APA, Harvard, Vancouver, ISO, and other styles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!