Relevant bibliographies by topics / Super Disintegrant

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters

Academic literature on the topic 'Super Disintegrant'

Author: Grafiati
Published: 7 June 2025
Last updated: 2 August 2025

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Journal articles on the topic "Super Disintegrant"

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Fahmansyah, Lingga Pratama, Agus S, and Suparman. "REVIEW : OF SUPERDISINTEGRANT INGREDIENTS IN FAST DISINTEGRANT TABLET TABLET PREPARATIONS." Medical Sains : Jurnal Ilmiah Kefarmasian 9, no. 3 (2024): 857–76. http://dx.doi.org/10.37874/ms.v9i3.1292.

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This study aimed to evaluate the potential of synthetic and natural disintegrating agents in fast-disintegrating tablet (FDT) formulations. The methodology used includes a comprehensive literature review on the definition, characteristics, working mechanisms, and applications of super disintegrants in the manufacture of FDTs. The results of the study showed that super disintegrants play an important role in facilitating rapid disintegration of tablets. Synthetic super disintegrants such as crospovidone, croscarmellose sodium, and sodium starch glycolate have the advantage of lower concentratio
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Vishwasrao, S. S., and A. Jadhav. "STUDIES ON FORMULATION AND EVALUATION OF ORALLY DISINTEGRATING TABLETS USING MUSA ACUMINATA AS A NATURAL DISINTEGRANT FOR PAEDIATRIC USE." INDIAN DRUGS 53, no. 12 (2016): 55–58. http://dx.doi.org/10.53879/id.53.12.10628.

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The aim of the present study was to optimize an orally disintegrating tablet of ibuprofen (~100mg) using Musa acuminata (dehydrated banana powder) as a natural super disintegrant. In this work, dehydrated banana powder was used as pharmaceutical excipient because of natural origin and high nutrition properties for paediatric formulation. These tablets were prepared by direct compression technique and compared with formulations made by using synthetic super disintegrants Croscarmellose sodium, micro crystalline cellulose and Cross povidone. FTIR studies of formulations have shown no interaction
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Azubuike, Chukwuemeka P., Uloma N. Ubani-Ukoma, Abiola R. Afolabi, and Ibilola M. Cardoso-Daodu. "Evaluation of super-disintegrant potential of acid-modified starch derived from Borassus aethiopum (Aracaceae) shoot in paracetamol tablet formulations." Tropical Journal of Pharmaceutical Research 19, no. 3 (2020): 459–65. http://dx.doi.org/10.4314/tjpr.v19i3.1.

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Purpose: To evaluate the super-disintegrant potentials of acid modified Borassus aethiopum starch (AMS) in comparison with native starch (NS) and commercial disintegrant sodium starch glycolate (SSG).
 Methods: Compatibility of AMS with paracetamol powder was evaluated using Fourier transform infrared (FTIR) spectrophotometry. Seven batches of paracetamol granules and tablets were prepared by wet granulation. AMS and NS were employed as disintegrants at concentrations of 2.43, 4.86 and 9.72 %w/w, respectively while 4.86 %w/w SSG was used as standard disintegrant. All the batches of the gr
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Raziya, Begum Sheikh. "Development and Assessment of Naproxen Mouth Dissolving Tablets." medtigo Journal of Pharmacology 1, no. 1 (2024): e13377773. https://doi.org/10.5281/zenodo.13377773.

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The market demand for orally disintegrating tablets has experienced a significant surge over the past decade. This intervention is particularly beneficial for geriatric and pediatric patients who experience challenges in ingesting traditional tablets and capsules. The utilization of a fast dissolving or fast disintegrating dosage form confers advantages to patients in this context. Fast dissolvable or fast disintegrating dosage forms are designed to rapidly disintegrate upon exposure to saliva, resulting in accelerated drug release within the oral cavity. The administration of fast-disintegrat
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Kute, S. Shivaji*1 Sonwane Sonali S*2 Jadhav Vaibhav A2. "Super Disintegrants: An Overview." International Journal in Pharmaceutical Sciences 2, no. 1 (2024): 77–89. https://doi.org/10.5281/zenodo.10464297.

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Disintegrants play a crucial role as excipients in solid oral formulations. In immediate release and oral dispersible tablet formulations, super disintegrants like croscarmellose sodium, sodium starch glycolate, crospovidone, and polacrilin potassium are added in small quantities to counteract the effects of compression and binder after administration. The hygroscopic nature of these super disintegrants facilitates the penetration of water into the tablet matrix, while their cross-linkage reduces solubility in water. This article provides an overview of various factors that can influence the f
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Gurram, Syam Sundar, Nagaveni P, and Sreevalli Arigela. "Formulation and evaluation of nifedipine fast dissolving tablets." Future Journal of Pharmaceuticals and Health Sciences 4, no. 2 (2024): 32–38. http://dx.doi.org/10.26452/fjphs.v4i2.599.

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The current study aims to formulate and evaluate the fast-dissolving tablet. The optimal concentration of Guar gum super disintegrate was found to be 20 mg, with a disintegration time of 27 seconds. This study assessed the disintegration time of tablets containing natural super disintegrant for the Disintegration test at various weight concentrations (6,8,10,12,14,16,18, and 20 mg). As a result, the Nifedipine fast dissolving tablets with Guar gum super disintegrant provide a quick therapeutic effect, a high dissolve rate, and a shorter disintegration time. In this study, the use of a natural
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Gurram, Syam Sundar. "Formulation and evaluation of nifedipine fast dissolving tablets." Formulation and evaluation of nifedipine fast dissolving tablets 4, no. 2 (2025): 32–38. https://doi.org/10.5281/zenodo.14651206.

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The current study aims to formulate and evaluate the fast-dissolving tablet. The optimal concentration of Guar gum super disintegrate was found to be 20 mg, with a disintegration time of 27 seconds. This study assessed the disintegration time of tablets containing natural super disintegrant for the Disintegration test at various weight concentrations (6,8,10,12,14,16,18, and 20 mg). As a result, the Nifedipine fast dissolving tablets with Guar gum super disintegrant provide a quick therapeutic effect, a high dissolve rate, and a shorter disintegration time. In this study, the use of a natural
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Sahoo, Suvendu, and Samyuktha Metta. "An Exploration of The Potential of Natural Super Disintegrating Agents in Pharmaceutical Formulations: A Review." Journal of Pharmacological and Pharmaceutical Research 1, no. 1 (2024): 21. http://dx.doi.org/10.5455/jppr.20240107023841.

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This review delves into the use of natural super disintegrating agents in pharmaceutical drug formulations. Disintegrants are incorporated into these formulations to aid in breaking down tablets and capsules, promoting rapid dissolution by facilitating their dispersion into smaller particles. Super disintegrants, distinguished by their notable swelling capacity, play a pivotal role in expediting drug disintegration within the gastrointestinal tract. The selection of an appropriate super disintegrant hinges on several factors, including chemical compatibility, swelling potential, disintegration
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Puri, Abhijeet Vishnu, Prakash D. Khandagale, Ankita U. Tiwari, Rekhadevi H. Chaudhary, and Sonam B. Kartan. "Synthesis and Physicochemical Characterization of Banana Starch Tartrate and its Application as Disintegrant in Telmisartan Tablets." Journal of Drug Delivery and Therapeutics 10, no. 3 (2020): 65–72. http://dx.doi.org/10.22270/jddt.v10i3.4089.

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The present investigation was aimed to isolate banana starch (BS), synthesis of banana starch tartrate (BST), characterization, and application as a novel disintegrant in telmisartan tablets. Starch tartrate was synthesized by the esterification process by the treatment of tartaric acid on the backbone of the BS. Synthesized BST was found to be fine, slightly free-flowing and crystalline powder. The synthesized BST was subjected to Scanning Electron Microscopy (SEM) and micrometric evaluation. Flow properties of BS and BST were determined as an angle of repose, bulk density, tapped density, Ca
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Nabila Nabila and Sry Ulina Karo-Karo. "Exploring natural disintegrant as alternative excipients sources for tablet formulation: A systematic review." International Journal of Science and Research Archive 13, no. 2 (2024): 3296–305. https://doi.org/10.30574/ijsra.2024.13.2.2530.

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Optimizing the disintegration and dissolution of orally administered tablets is crucial for releasing active pharmaceutical ingredients (APIs) for absorption. This review explores disintegrant research, focusing on natural super disintegrants and co-processed excipients that collected from 2010-2024. Natural disintegrants such as Silicified Oryza Sativa Starch, Plantago ovata mucilage, and gum karaya show promising results. Silicified Oryza Sativa Starch enhances paracetamol tablet disintegration, while Plantago ovata mucilage outperforms Crosspovidone. Gum karaya offers a cost-effective, bioc
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Dissertations / Theses on the topic "Super Disintegrant"

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Soulairol, Ian. "Etude des phénomènes liés à la conception de mini-comprimés orodispersibles par compression directe." Thesis, Montpellier, 2017. http://www.theses.fr/2017MONTT115/document.

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La possibilité d’administrer des formes sèches orales est encore de nos jours un enjeu dans certaines spécialités médicales telles que la pédiatrie, la neurologie ou la gériatrie. Les mini-comprimés orodispersibles présentent un intérêt majeur pour répondre à cette problématique.L’objectif de ce travail est d’étudier les différents phénomènes qui régissent la conception de cette forme pharmaceutique par compression directe.Trois axes de recherche ont été fixés pour la réalisation de ce travail : - Premièrement, étudier les paramètres de formulation et de fabrication des mini-comprimés orodispe
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Book chapters on the topic "Super Disintegrant"

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Devi, Medisetty Gayatri, Kumar R. Santosh, and Anusha Kusuma. "Design, optimization and evaluation of telmisartan fast dissolving film employing mango kernel starch as a new natural super disintegrant." In Advancement in Animal Handling and Generative AI for Pre-clinical Studies. CRC Press, 2025. https://doi.org/10.1201/9781003672869-15.

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Noothi, Sadhana, Narender Malothu, and P. Vishnu. "Formulation and Characterization of Bilastine Oral Disintegrated Tablets Using Natural and Synthetic Super Disintegrants." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00361.

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Bilastine (BLS) is a second-generation H1- antihistamine that is approved recently for the symptomatic treatment of chronic urticaria. The present investigation was to develop oral disintegrating tablets of BLS to produce a fast onset of action. In this study, an attempt was made to compare the effect of different natural and synthetic super disintegrants on the release profile of the formulation. The formulations (BF1-BF15) of BLS oral disintegrating tablets were prepared by direct compression technique using synthetic and natural super disintegrants (Chitosan, Fenugreek mucilage, Sodium star
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"Super Disintegrants: Characterization and Function." In Encyclopedia of Pharmaceutical Technology. CRC Press, 2013. http://dx.doi.org/10.1201/b19309-12.

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Y., Ismail, and V. Vijaya Kumar. "Design, Charecterization of Imidapril Mouth Dissolving Tablets Using Super Disintegrants." In Advanced Concepts in Pharmaceutical Research Vol. 4. B P International, 2024. http://dx.doi.org/10.9734/bpi/acpr/v4/6646c.

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Ismail, Y., and Voleti Vijaya Kumar. "Development and Assessment of Fast-Dissolving Tablets of Levocetirizine Dihydrochloride Using Super Disintegrants." In Pharmaceutical Science: New Insights and Developments Vol. 5. BP International, 2025. https://doi.org/10.9734/bpi/psnid/v5/4878.

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Devi, V. Rupa Sree, M. Sukanya, K. Ravi Shankar, G. Ramana Reddy, and KNV Chenchu Lakshmi. "Formulation, Preparation, and Evaluation of Nebivolol Fast-Dissolving Tablets by Using 32 Factorial Design." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00510.

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Nebivolol comes under BCS Class II Classification, so there is a need to improve the dissolution rate. The motive of the current work is to formulate the fast-dissolving tablets of Nebivolol from optimised solid dispersion by allowing complexation using solid dispersions of PEG 4000, Starch 1500, Poloxamer 188, and β-cyclodextrin (β CD). Nebivolol tablets with fast dissolution characteristics employing βCD were prepared using a 32 factorial study employing by direct compression technique. Dissolution of Nebivolol from the β-CD complexes was rapid and higher when seen with that of Pure Nebivolo
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Sukanya, M., V. Rupa Sree Devi, K. Ravi Shankar, G. Ramana Reddy, and R. Anusha. "Optimization of Telmisartan Fast Dissolving Tablets by 32 Factorial Design." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00533.

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Telmisartan belongs to BCS Class II drug and needs enhancement in dissolution rate. The main objective of the study is to produce rapid dissolving tablets of telmisartan by complexation with β-cyclodextrin(βCD) and by using solid dispersions of MCC, Starch 1500, PEG 4000, Primojel and Mannitol. Telmisartan tablets with fast dissolution characteristics employing βCD were prepared using 32 factorial design and were prepared by direct compression method. Dissolution of Telmisartan from the βCD complexes was rapid and higher when compared to Telmisartan pure drug and with different carriers. Hence
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