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Journal articles on the topic 'Superovulation protocol'

Author: Grafiati

Published: 11 December 2022

Last updated: 31 July 2025

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1

Pasco, Rachael, David K. Gardner, David W. Walker, and Hayley Dickinson. "A superovulation protocol for the spiny mouse (Acomys cahirinus)." Reproduction, Fertility and Development 24, no. 8 (2012): 1117. http://dx.doi.org/10.1071/rd12044.

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This study aimed to develop a superovulation protocol for the spiny mouse (Acomys cahirinus). The spiny mouse is a desert-adapted rodent species, with a long oestrus cycle (11 days) compared with rat and mouse, and gives birth to few (mean litter size is 3) precocial offspring after a relatively long gestation (39 days). We successfully optimised a superovulation protocol that elicited a 5-fold increase in the normal ovulation rate of this species. To induce superovulation in the spiny mouse 2 injections of equine chorionic gonadotrophin (eCG, 10 IU each), 9 h apart, were required, followed by

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2

Mitwally, M. F., T. Said, A. Galal, et al. "Letrozole Step-Up Protocol: a Successful Superovulation Protocol." Fertility and Sterility 89, no. 4 (2008): S23—S24. http://dx.doi.org/10.1016/j.fertnstert.2008.02.071.

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3

Waqas, Muhammad-Salman, and Ahmed Tibary. "Manipulation of ovarian function in sheep and goats." Clinical Theriogenology 17 (February 14, 2025): 24–35. https://doi.org/10.58292/ct.v17.11653.

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Sheep and goats are short-day breeders. Melatonin, photoperiod, breed, nutrition, and geographical location influence seasonality. Estrus synchronization is useful in maximizing the profitability of small ruminant production. This article discusses the endocrine control of seasonality and the reproductive cycle, and manipulation of ovarian function in sheep and goats. The ovarian follicular wave pattern in these species is described to help the reader understand the mechanisms involved in the protocols for estrus synchronization and superovulation in small ruminants. The estrus synchronization

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Mahmood, Khalid, Muhammad Zahid Tahir, Mahboob Ahmad Butt, Shazia Mansoor Qureshi, and Amjad Riaz. "GnRH or estradiol benzoate combination with CIDR improves in-vivo embryo production in bovines (Bos indicus and Bos taurus) under subtropics." PeerJ 9 (September 16, 2021): e12077. http://dx.doi.org/10.7717/peerj.12077.

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Multiple Ovulation and Embryo Transfer (MOET) technology is a potential technique to upgrade livestock species’ genetics. The varied response to super-stimulatory treatments remains one of the limiting factors to this technology’s widespread use. The present study was aimed to improve the superovulation response and in-vivo embryo production by using controlled internal drug release (CIDR)-GnRH or CIDR-EB (Estradiol Benzoate) along with conventional superovulation protocol in Holstein Frisian (HF): Bos taurus; n = 42) and Crossbred (XB: Cholistani (Bos indicus) × HF; n = 28) cows. In the CIDR-

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Barfield, J. P., and G. E. Seidel. "311 SUPEROVULATION OF NORTH AMERICAN BISON WITH TWO INJECTIONS OF FOLLICLE-STIMULATING HORMONE." Reproduction, Fertility and Development 25, no. 1 (2013): 302. http://dx.doi.org/10.1071/rdv25n1ab311.

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Few studies have examined superovulation of North American Bison. In cattle, ovarian superstimulation is usually achieved with 6 to 8 injections of FSH at half-day intervals. However, handling bison repeatedly stresses the animals, which could adversely affect their reproductive potential, as well as pose a risk of injury to the bison and handlers. To limit the number of times the bison were handled, we tested a two-injection superovulation scheme using sodium hyaluronate (MAP-5, Bioniche Animal Health Inc., Belleville, Ontario, Canada) in the FSH diluent, which serves to slow the absorption o

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Baharun, Abdullah, Athhar Diansyah, Ristika Handarini, et al. "<b>A comparative study of intramuscular versus epidural administration of follicle-stimulating hormone for embryo production in Wagyu cattle</b>." Open Veterinary Journal 15, no. 5 (2025): 2103. https://doi.org/10.5455/ovj.2025.v15.i5.28.

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Background: The increasing demand for high-quality livestock products necessitates the optimization of reproductive technologies, particularly superovulation and embryo transfer, to enhance genetic improvement and productivity. Superovulation increases embryo availability and accelerates genetic enhancement. The success of these techniques depends on factors such as hormone protocols, donor-recipient selection, and environmental conditions. Aim: This study aimed to compared two superovulation protocols—conventional intramuscular injection (P1) and combined epidural-intramuscular injection (P2)

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Ostrina, S. Ya, O. F. Serova, E. B. Rudakova, and E. A. Fedorova. "Personalized approach to ovarian stimulation in patients with paradoxical response in IVF programs." A.I. Burnasyan Federal Medical Biophysical Center Clinical Bulletin, no. 4 (December 2022): 26–29. http://dx.doi.org/10.33266/2782-6430-2022-4-26-29.

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Presented are current data on the need to identify the main groups of patients in in vitro fertilization programs that require a personalized protocol for ovarian stimulation and modification of traditional ovarian stimulation protocols in in vitro fertilization programs. The influence of polymorphism of gonadotropin receptor genes on the ovarian response during superovulation induction was shown.

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Bó, Gabriel A., Daniel Carballo Guerrero, Andrés Tríbulo, et al. "New approaches to superovulation in the cow." Reproduction, Fertility and Development 22, no. 1 (2010): 106. http://dx.doi.org/10.1071/rd09226.

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There is continuing need to simplify bovine superovulation protocols without compromising embryo production. The control of follicular wave emergence and ovulation has facilitated donor management, but the most commonly used treatment, oestradiol, cannot be used in many parts of the world and mechanical removal of the dominant follicle is difficult to apply in the field. Other alternatives include gonadotrophin-releasing hormone (GnRH) or LH, but efficacy in groups of randomly cycling animals is variable. Another alternative is to increase the response to GnRH by inducing a persistent follicle

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9

Dorsch, M. M., S. Glage, and H. J. Hedrich. "Collection and cryopreservation of preimplantation embryos of Cavia porcellus." Laboratory Animals 42, no. 4 (2008): 489–94. http://dx.doi.org/10.1258/la.2007.007011.

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Summary Individual differences and a rather long-lasting reproductive cycle, as well as the relatively small number of oocytes that mature during one reproductive cycle makes it difficult to establish a cryopreserved stock of preimplantation embryos of the guineapig ( Cavia porcellus) when compared with other laboratory rodents. Only a few data for superovulation protocols that can be used for routine laboratory use in guineapigs are available. However, a huge number of different strains exist for many purposes and the establishment of a frozen repository makes sense. Here, we describe the suc

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10

Hedon, B., B. Camier, F. Arnal, and C. Humeau. "What is the best protocol for ovarian superovulation?" Journal of Assisted Reproduction and Genetics 10, no. 7 (1993): 453–57. http://dx.doi.org/10.1007/bf01212930.

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11

Silva, B. D. M., T. A. S. N. Silva, L. Dalcin, C. M. Lucci, and J. P. Neves. "418 EFFECT OF SUPEROVULATION INITIATED AT FOLLICULAR WAVE EMERGENCE IN Santa Inês EWES." Reproduction, Fertility and Development 22, no. 1 (2010): 366. http://dx.doi.org/10.1071/rdv22n1ab418.

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Superovulation in ewes has been a source of many studies aimed at obtaining high superovulatory response and number of viable embryos recovered. In a protocol called Day 0, superovulatory treatment was initiated at the time of wave emergence in the absence of a dominant follicle (Menchaca A et al. 2002 Theriogenology 58, 1713-1721). The aim of this study was to compare ovarian response and number of embryos recovered after treatment between ewes treated with a Day 0 protocol and those treated with a traditional protocol. Santa InÊs ewes (n= 18) between 2 and 5 years old were randomly distribut

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12

Adah, Adakole. "Haematological Responses following Oestrus synchronisation and superovulation protocols in West African Dwarf Goats." Media Kedokteran Hewan 34, no. 1 (2023): 27–35. http://dx.doi.org/10.20473/mkh.v34i1.2023.27-35.

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Experiments were performed to evaluate the haematological (erythrocyte and leucocyte parameters) response of West African Dwarf goats following oestrus synchronisation and superovulation protocol. Twenty-four clinically healthy female goats aged 2.34 ± 0.4 years and average body weight of 13.83 ± 0.7 kg was used for the experiment. The goats were divided into two groups. Group I goats was synchronized using Controlled Internal Drug Release (CIDR) for 18 days with the first day of insertion as day 0. On day 16 following CIDR insertion into the vagina, a single dose of 500 IU equine chorionic go

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13

Gutiérrez-Reinoso, Miguel A., Constanza J. Aguilera, Felipe Navarrete, et al. "Effects of Extra-Long-Acting Recombinant Bovine FSH (bscrFSH) on Cattle Superovulation." Animals 12, no. 2 (2022): 153. http://dx.doi.org/10.3390/ani12020153.

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Over the last few years, several commercial FSH products have been developed for cattle superovulation (SOV) purposes in Multiple Ovulation and Embryo Transfer (MOET) programs. The SOV response is highly variable among individuals and remains one of the main limiting factors in obtaining a profitable number of transferable embryos. In this study, follicle stimulating hormone (FSH) from different origins was included in two SOV protocols, (a) FSH from purified pig pituitary extract (NIH-FSH-p; two doses/day, 12 h apart, four consecutive days); and (b) extra-long-acting bovine recombinant FSH (b

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14

ADEL, Djallal, Kamal TOUATI, and Rachid KAIDI. "Effect of the Reduction in the Frequency of Injections of Pituitary Extracts During a Superovulation on the Embryo Collection Results in Cows in Algeria." Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Veterinary Medicine 75, no. 1 (2018): 9. http://dx.doi.org/10.15835/buasvmcn-vm:001217.

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The aim of this study is to verify the efficacy of a superovulation treatment with 3 injections of pituitary extracts (Stimufol®) 24 hours apart and compare the results to a standard protocol (8 injections 12 hours apart), with a total dose of 500 μg. Twenty-three embryos collections were conducted after two superovulation protocols, the first with 8 injections 12 hours apart and decreasing doses (n = 11, group 1) and the second 3 injections at constant doses 24 hours of interval (n = 12, group 2). The average number of lutea corpora obtained is 9.1 per cow for group 1 and 10.4 in group 2. A t

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15

Mogase, C. R., K. C. Lehloenya, and M. Dattena. "Applicability of Day 0 superovulation protocol in Boer goats." Small Ruminant Research 136 (March 2016): 261–64. http://dx.doi.org/10.1016/j.smallrumres.2016.02.012.

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16

Savchenko, E. S., N. S. Ogneva, S. V. Maksimenko, M. M. Skripkina, and N. V. Petrova. "Optimizing the Hormonal Mice Treatment Protocol to Induce Superovulation." Journal Biomed 16, no. 3 (2020): 48–53. http://dx.doi.org/10.33647/2074-5982-16-3-48-53.

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Mice treatment with pregnant mare gonadotropin serum (PMGS) in combination with human chorionic gonadotropin (hCG) is considered to be the “golden standard” of the induced superovulation procedure. The effect of administering the same doses may differ depending on the manufacturer of the preparation. According to our results, the use of PMGS produced by Synchrostim 500 (Ceva Sante Animale, France) and Sergon (Bioveta, Czech Republic) at a hormone dose of 5ME allows ~25 embryos to be obtained from one female. At the same time, the working dose of Follimagum (Mosagrogen, Russia) was not determin

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17

Cortell, Carmela, Pascal Salvetti, Thierry Joly, and Maria Pilar Viudes-de-Castro. "Effect of different superovulation stimulation protocols on adenosine triphosphate concentration in rabbit oocytes." Zygote 23, no. 4 (2014): 507–13. http://dx.doi.org/10.1017/s0967199414000112.

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SummaryOvarian stimulation protocols are used usually to increase the number of oocytes collected. The determination of how oocyte quality may be affected by these superovulation procedures, therefore, would be very useful. There is a high correlation between oocyte ATP concentration and developmental competence of the resulting embryo. The aim of this study was to evaluate the effect of follicle stimulating hormone (FSH) origin and administration protocols on oocyte ATP content. Rabbit does were distributed randomly into four groups: (i) a control group; (ii) the rhFSH3 group: females were in

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18

Menchaca, A., M. Vilariño, M. Crispo, T. de Castro, and E. Rubianes. "New approaches to superovulation and embryo transfer in small ruminants." Reproduction, Fertility and Development 22, no. 1 (2010): 113. http://dx.doi.org/10.1071/rd09222.

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The present paper reviews the current state of knowledge in multiple ovulation and embryo transfer (MOET) technology in small ruminants, focusing on recently reported information. Major new findings are related to follicular wave patterns in small ruminants, the elucidation of follicular dominance and the integration of this information into ovarian superstimulatory treatment protocols. Follicular dynamics determine steroid and gonadotrophin secretion, follicular responses to FSH, ovulatory responses and embryo yield. Protocols that control follicular dominance have been designed to allow the

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19

Mapletoft, Reuben J., and Gabriel A. Bó. "The evolution of improved and simplified superovulation protocols in cattle." Reproduction, Fertility and Development 24, no. 1 (2012): 278. http://dx.doi.org/10.1071/rd11919.

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Superovulation protocols have improved greatly since the early days of bovine embryo transfer when purified gonadotrophins were not available, follicular wave dynamics were unknown physiological phenomena and prostaglandins were not available. Although superstimulatory protocols in cattle are normally initiated mid-cycle, elective control of follicular wave emergence and ovulation have had a great impact on the application of on-farm embryo transfer. However, the most common treatment for the synchronisation of follicular wave emergence involves the use of oestradiol, which cannot be used in m

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20

Sugawara, M., Y. Kaneda, A. Miyoshi, H. Sekizawa та O. Dochi. "201 EFFECT OF A SINGLE SUBCUTANEOUS INJECTION OF FSH AND TIMING OF PROSTAGLANDIN F2α ADMINISTRATION ON SUPEROVULATORY RESPONSE IN JAPANESE BLACK COWS". Reproduction, Fertility and Development 29, № 1 (2017): 209. http://dx.doi.org/10.1071/rdv29n1ab201.

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Superovulation treatment using FSH requires injection twice a day, for 3 to 4 days. This conventional method requires frequent handling of donors and higher labour costs. Therefore, simplification of the superovulation treatment protocol is needed to reduce animal handling and labour costs. The objective of this study was to investigate the effect of a single subcutaneous FSH injection and the timing of prostaglandin F2α (PGF; cloprostenol) administration on the superovulatory response in Japanese Black cows (Hiraizumi et al. 2015 Theriogenology 83, 466–473) and to determine whether the supero

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Lehloenya, Khoboso C. "Preliminary results evaluating a simplified superovulation protocol in Boer goats." Small Ruminant Research 113, no. 1 (2013): 171–74. http://dx.doi.org/10.1016/j.smallrumres.2013.03.017.

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22

Bagatko, O. V., and N. O. Dankovich. "The effectiveness of tubal infertility treatment in ART programs depending on ovarian stimulation protocol." HEALTH OF WOMAN, no. 9(125) (November 30, 2017): 114–16. http://dx.doi.org/10.15574/hw.2017.125.114.

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The objective: of the investigation was to study the effectiveness of treatment of women with tubal infertility, depending on the protocol of ovarian stimulation. Materials and methods. To achieve tht goal, the medical documentation of patients who contacted the «Mother and Child» Medical Center in 2012-2013 was analyzed. To compare the efficacy of different ovarian stimulation protocols were selected 387 patients under the age of 35 years with tubal infertility, who were stimulated by standard protocols with further separation into two groups: S (short stimulation protocol, n=246) and L (long

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Chayka, О. О. "Effectiveness of in vitro fertilization (IVF/ICSI) programs in patients with a predicted poor ovarian response." UKRAINIAN JOURNAL HEALTH OF WOMAN, no. 4(164) (September 26, 2022): 27–31. http://dx.doi.org/10.15574/hw.2022.161.27.

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Purpose - to show the effectiveness of in vitro fertilization (IVF) programs in infertile women with a predicted poor ovarian response to stimulation with various gonadotropins and to study the course of pregnancy, childbirth and the condition of their newborns. Materials and methods. The Group І is 75 women, the controlled stimulation of superovulation in which by urinary gonadotropins was performed in the protocol with the use of gonadotropin-releasing hormone antagonist. The Group ІІ (comparison) is 65 women, the stimulation of superovulation in which was carried out according to an analogi

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Panyaboriban, S., J. Suwimonteerabutr, T. Swangchan-Uthai, et al. "A simplified superovulation protocol using split-single administration of Folltropin®-V in hyaluronan: application to purebred sheep." Veterinární Medicína 63, No. 7 (2018): 321–28. http://dx.doi.org/10.17221/52/2016-vetmed.

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Superovulation is an important step in assisted reproductive technology. Due to its short half-life, follicle stimulating hormone is usually given twice daily to ewes for three to five days, which is both time- and labour-intensive. However, dissolving follicle stimulating hormone in degradable polymers to delay absorbtion has been effective in ruminants. Experiment 1 was performed to compare a split-single follicle stimulating hormone dissolved in hyaluronan (S group; 150 mg follicle stimulating hormone on the first day and 30 mg 48 h later; n = 21) and six decreasing doses of follicle stimul

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Barros, Ciro M., Ronaldo L. Ereno, Renato A. L. Simões, Paulo Fernandes, José Buratini, and Marcelo F. G. Nogueira. "Use of knowledge regarding LH receptors to improve superstimulatory treatments in cattle." Reproduction, Fertility and Development 22, no. 1 (2010): 132. http://dx.doi.org/10.1071/rd09227.

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Embryo transfer is a biotechnology that has been used worldwide to increase the production of offspring from female bovines. Treatments to induce multiple ovulations (superovulation) have evolved from superstimulatory protocols that depended upon detection of oestrus to treatments that synchronise follicle growth and ovulation, allowing for improved donor management and fixed-timed AI (FTAI). The protocols associated with FTAI facilitate animal handling and produce at least as many viably embryos as conventional treatment protocols that required detection of oestrus. Recent knowledge regarding

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Li, Dongxu, Xiangli Wu, Ying Chen, et al. "Exploration of Conditions for the Scaled Application of Laparoscopic Ovum Pick-Up in Sheep and Comparison of Follicular Development Differences Among Breeds." International Journal of Molecular Sciences 26, no. 5 (2025): 1989. https://doi.org/10.3390/ijms26051989.

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In small ruminants, laparotomy for ovarian exploration followed by oocyte collection has been progressively replaced by laparoscopic puncture of follicles, which has become an important method for obtaining oocytes in vivo. However, the superovulation protocols and collection frequency used for laparoscopic ovum pick-up (LOPU) in sheep still require further investigation. This study explored the factors influencing LOPU efficiency in sheep, including Controlled Internal Drug Release (CIDR) for estrus synchronization, FSH source and dose, and recovery intervals. The optimal superovulation proto

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McKenna, Jarrod, Nadia Bellofiore, Sally Catt, Mulyoto Pangestu, and Peter Temple-Smith. "A human-based assisted reproduction protocol for the menstruating spiny mouse, Acomys cahirinus." PLOS ONE 15, no. 12 (2020): e0244411. http://dx.doi.org/10.1371/journal.pone.0244411.

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The Egyptian or Common spiny mouse (A. cahirinus) is the first rodent species to show human-like menstruation and spontaneous decidualisation. We consider from these, and its other, human-like characteristics that this species will be a more useful and appropriate small animal model for human reproductive studies. Based on this, there is a need to develop specific laboratory-based assisted reproduction protocols including superovulation, in-vitro fertilisation, embryo cryopreservation and transfer to expand and make this model more relevant. Because standard rodent superovulation has not been

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Abshekenova, A. T., A. N. Rybina, E. Askar, Sh K. Karibaeva, R. K. Valiev, and V. N. Lokshin. "Experience in using biosimilars in IVF programs with donor oocytes in protocols with micronized progesterone." Репродуктивная медицина, no. 1 (April 1, 2024): 27–33. http://dx.doi.org/10.37800/rm.1.2024.27-33.

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Relevance: Stimulation of oocyte donors' superovulation occupies a key place in the development of general assisted reproduction technology (ART). Oocyte donation programs involve young and healthy women undergoing severe ovarian stimulation protocols to obtain good-quality oocytes. Advances in recombinant DNA technology led to the development of recombinant follitropin alfa.The study aimed to evaluate the effectiveness of the biosimilar folitropin alfa in the superovulation stimulation cycles of oocyte donors in comparison with the original medication in Progestin primed ovarian stimulation (

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García Fernández, R. A., P. García-Palencia, B. Sánchez Maldonado, et al. "Characterization of Decidual Reaction in a Superovulation Protocol in C57BL/6J Mice." Journal of Comparative Pathology 156, no. 1 (2017): 133. http://dx.doi.org/10.1016/j.jcpa.2016.11.240.

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30

Aboul Enien, Wafaa. "A MINIMAL STIMULATION PROTOCOL WITH SIMPLIFIED MONITORING FOR SUPEROVULATION AND INTRAUTERINE INSEMINATION." Egyptian Journal of Fertility of Sterility 8, no. 2 (2004): 51–58. http://dx.doi.org/10.21608/egyfs.2004.5011.

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31

Nagori, Chaitanya. "Ultrasound-based Decision Making on Stimulation Protocol for Superovulated Intrauterine Insemination Cycles." International Journal of Infertility & Fetal Medicine 7, no. 1 (2016): 7–13. http://dx.doi.org/10.5005/jp-journals-10016-1119.

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ABSTRACT Deciding optimum stimulation protocols is one of the most important factors for the success of any assisted reproductive technologies. We have used ultrasound parameters chiefly with age and basal mass index (BMI) to decide stimulation protocols in intrauterine insemination (IUI) cycles. The parameters used on ultrasound were ovarian size (volume), number of antral follicles, ovarian stromal resistance index, and peak systolic velocity. A scoring system was developed according to the values of these parameters with age and BMI of the patient. This scoring system has been used to decid

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Sumantri, Cece, M. Imron, Sugyono ., E. Andreas, M. Restu, and A. B. L. Ishak. "Growth hormone gene family (GH, GHR, GHRH and Pit-1) polymorphisms and its association with superovulation response, ovulation rate and embryo quality in Embryo Transfer Station (BET) of Cipelang." Jurnal Ilmu Ternak dan Veteriner 16, no. 2 (2012): 126–39. https://doi.org/10.14334/jitv.v16i2.642.

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The decrease in fertility is considered to be the main cause of reproductive loss in dairy cattle and beef industry. Many candidate genes that play an important role in fertility and embryonic development. The purpose of this study was to detect genetic variations of the growth hormone gene family (GH|MspI, GH|AluI, GHR| AluI, GHRH|HaeIII and Pit-1|HinfI) and its association with superovulation response, ovulation, fertilization and transferable embryos rate. A total of 45 blood samples taken from cows that have been superovulated Angus, Brahman, HF, Limousin and Simmental. DNA was extracted w

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Popov, D. V., W. Yu Babenkov, T. T. Glazko, and G. Yu Kosovsky. "Use of gonadotropins on females of agricultural species with year-round and seasonal type of reproduction." Bulletin of NSAU (Novosibirsk State Agrarian University), no. 1 (April 16, 2025): 194–214. https://doi.org/10.31677/2072-6724-2025-74-1-194-214.

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In this work we determined the efficiency of induction of superovulation and folliculogenesis in females of agricultural species with low- and multiple-fetal type of pregnancy, as well as with seasonal and year-round manifestation of estrus, by different modes of FSH-super preparation administration. For the first time studies on the use of pituitary gonadotropins on females with different types of reproduction for the induction of superovulation, folliculogenesis and ovulation in different seasons of the year were conducted. Superovulation induction was performed in embryo donor cows of speci

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Pereira, Alécio Matos, Antônio de Souza Júnior, Fernanda Brandão Machado, et al. "The effect of angiotensin-converting enzyme inhibition throughout a superovulation protocol in ewes." Research in Veterinary Science 103 (December 2015): 205–10. http://dx.doi.org/10.1016/j.rvsc.2015.10.013.

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35

Ellington, Joanna E., Paul B. Farrell, Michael E. Simkin, and Robert H. Foote. "Method for obtaining bovine zygotes produced in vivo." American Journal of Veterinary Research 51, no. 11 (1990): 1708–10. http://dx.doi.org/10.2460/ajvr.1990.51.11.1708.

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SUMMARY A superovulatory and surgical protocol was developed for recovery of bovine zygotes. Holstein cows and heifers were given follicle-stimulating hormone and cloprostenol to induce superovulation. Surgical cannulation and lavage of the uterine tube was performed 40 to 48 hours after the start of standing estrus. In general, cows had more corpora hemorrhagica than did heifers, but a higher percentage (P < 0.05) of ova recovered from cows were infertile. Several heifers were subjected to the procedure twice, and embryo recovery rates were equivalent both times.

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Fry, R. "200 THE USE OF LONG-ACTING FSH-MAP5 IN SHEEP SUPEROVULATION PROGRAMS." Reproduction, Fertility and Development 29, no. 1 (2017): 208. http://dx.doi.org/10.1071/rdv29n1ab200.

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The administration of sustained-release FSH-MAP5 in a 2-injection protocol has been shown to be as effective as a multiple-FSH injection protocol in inducing superovulation in cattle (Bo and Mapletoft 2014 Theriogenology 81, 38) and in sheep (Fry et al. 2016 Reprod. Fertil. Dev. 28, 250); however, the effect on embryo quality in the latter experiment was unclear. The following experiment further investigated the effect of FSH-MAP5 on ovulation rate and embryo quality in a sheep multiple-ovulation embryo transfer (MOET) program conducted in the breeding season. Two hundred sixteen Dohne merino

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Briant, C., PL Toutain, M. Ottogalli, T. Magallon, and D. Guillaume. "Kinetic studies and production rate of equine (e) FSH in ovariectomized pony mares. Application to the determination of a dosage regimen for eFSH in a superovulation treatment." Journal of Endocrinology 182, no. 1 (2004): 43–54. http://dx.doi.org/10.1677/joe.0.1820043.

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The appropriate dosage regimen for equine FSH (eFSH) (dose, dosing interval) administration in a superovulation treatment in pony mares was determined by a kinetic approach using production rates and kinetic parameters of elimination of the hormone. Two dosage regimens were then tested in superovulation protocols. The eFSH production rates were determined by sampling four ovariectomized pony mares every 10 min for 8 h during the breeding season. Kinetic parameters were determined by administering four dose levels of a preparation of eFSH (4.4, 8.8, 17.6 and 35.2 micro g/kg) by the i.v. route t

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ANASTASIADIS (Α. ΑΝΑΣΤΑΣΙΑΔΗΣ), A., G. C. AMIRIDIS (Γ. Σ. ΑΜΟΙΡΙΔΗΣ), A. G. LYMBEROPOULOS (Α.Γ. ΛΥΜΠΕΡΟΠΟΥΛΟΣ), A. KORONAKI (Α. ΚΟΡΩΝΑΚΗ), and E. VAINAS (Ε. ΒΑΪΝΑΣ). "Superovulation of prepubertal and young pubertal gilts with PMSG." Journal of the Hellenic Veterinary Medical Society 52, no. 4 (2018): 325. http://dx.doi.org/10.12681/jhvms.15465.

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The feasibility of application of a standardized protocol for estrous synchronization, superovulation and embryo transfer in young pubertal and pre-pubertal gilts under farm conditions was investigated. Two groups of Large white X Landrace crossbreed gilts were used. Group A (n = 16) consisted of pubertal (>6months old ) animals weighing 100-110 kg while group Β (n=ll) consisted of prepubertal gilts weighing 75-80 kg. Superovulation and estrous synchronization was conducted by intramuscular administration of 1500 IU of PMSG and 750 IU of hCG given 12 and 72 hours after the transfer of the g

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Barros, Ciro M., Rafael A. Satrapa, Anthony C. S. Castilho, et al. "Effect of superstimulatory treatments on the expression of genes related to ovulatory capacity, oocyte competence and embryo development in cattle." Reproduction, Fertility and Development 25, no. 1 (2013): 17. http://dx.doi.org/10.1071/rd12271.

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Multiple ovulation (superovulation) and embryo transfer has been used extensively in cattle. In the past decade, superstimulatory treatment protocols that synchronise follicle growth and ovulation, allowing for improved donor management and fixed-time AI (FTAI), have been developed for zebu (Bos indicus) and European (Bos taurus) breeds of cattle. There is evidence that additional stimulus with LH (through the administration of exogenous LH or equine chorionic gonadotrophin (eCG)) on the last day of the superstimulatory treatment protocol, called the ‘P-36 protocol’ for FTAI, can increase embr

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Sbracia, Marco, Julio Colabianchi, Annalise Giallonardo, et al. "Cetrorelix protocol versus gonadotropin-releasing hormone analog suppression long protocol for superovulation in intracytoplasmic sperm injection patients older than 40." Fertility and Sterility 91, no. 5 (2009): 1842–47. http://dx.doi.org/10.1016/j.fertnstert.2008.02.165.

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Robles, T. Garcia, R. A. García Fernández, P. García-Palencia, et al. "Hoxa-10 and Cyclin D3 Overexpression in the Decidual Reaction in a Superovulation Protocol in Young Adult C57BL/6J Mice." Veterinary Pathology 54, no. 2 (2016): 328–35. http://dx.doi.org/10.1177/0300985816660748.

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Following the performance of a superovulation protocol, multiple nodules were observed bilaterally in the uterine horns of 31 of 276 (11.2%) C57BL/6 J female mice aged 8.5 ± 0.6 (mean and standard error of mean) weeks. These lesions prevented embryo collection, and the uterine decidual reaction was suspected. Samples of pathological uteri (n = 20) and the normal genital tracts of donors treated with a similar superovulation protocol (control group, n = 10) were collected. Immunohistochemistry was performed to evaluate pancytokeratin, desmin, vimentin, progesterone receptor (PR), estrogen recep

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Wani, Sajad K., and Abida Gull. "Successful Pregnancy After IUI with Retrograde Ejaculated Sperm." JMS SKIMS 19, no. 2 (2016): 85–87. http://dx.doi.org/10.33883/jms.v19i2.294.

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Objective: To report a case of successful treatment of complete retrograde ejaculation by superovulation and intrauterine insemination (IUI), by collecting spermatozoa from post-ejaculatory urine.Design: Case report.Setting: Private infertility clinic (Harkaar Superspeciality Centre).Patient(s): A couple with primary infertility for 7 years due to male's complete retrograde ejaculation due to the congenital hypoplastic prostate gland. The woman was having subserosal fibroid but otherwise normal menstrual cycles. Intervention(s): Super-ovulation and Intrauterine insemination IUI was done after

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Carvajal Basto, J., A. Catube, A. Tribulo, R. Tribulo, and G. A. Bo. "162 Simplification of a superovulation protocol using FSH and equine chorionic gonadotrophin in beef donors." Reproduction, Fertility and Development 34, no. 2 (2022): 319. http://dx.doi.org/10.1071/rdv34n2ab162.

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Syrkasheva, Syrkasheva A. G., Agarsheva M. V. Agarsheva, Andreeva M. G. Andreeva, Dolgushina N. V. Dolgushina, Kalinina E. A. Kalinina, and Yarotskaya E. L. Yarotskaya. "Current views of a differentiated approach to choosing a superovulation stimulation protocol in IVF cycles." Akusherstvo i ginekologiia 5_2016 (May 27, 2016): 38–43. http://dx.doi.org/10.18565/aig.2016.5.38-43.

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M. EL-Sherry, Taymour. "No-CL Superstimulatory Protocol: Developing a New Superovulation Treatment Initiated in the Absence of Corpus Luteum (CL) and Compared with D1 and Traditional Superovulation in Cattle." Open Reproductive Science Journal 4, no. 1 (2012): 4–9. http://dx.doi.org/10.2174/1874255601204010004.

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Quinton, H., F. Charreaux, A. Morel, et al. "150 USING A LUTEINIZING HORMONE SURGE DETECTION TEST, PREDI'BOV®, TO OPTIMIZE THE TIME OF ARTIFICIAL INSEMINATION DURING A SUPEROVULATION PROTOCOL IN A HOLSTEIN HEIFERS HERD." Reproduction, Fertility and Development 27, no. 1 (2015): 166. http://dx.doi.org/10.1071/rdv27n1ab150.

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Insemination of superovulated bovine donors in due time is of central importance for fertilization and embryo viability. A preliminary test focusing on LH surge detection during superovulation (unpublished datas) indicated that one quarter of the donors present LH surges 12 to 24 h before heat observation (which could correspond, in the case of AI after heat observation, to post ovulation AI). Therefore, it was hypothesised that the average number of embryos per flush could be improved by inseminating donors with early LH surge 12 h after the beginning of the LH peak whenever the heat occurs.I

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Choi, S. H., K. H. Cho, and Y. S. Park. "292 EFFECT OF A SINGLE INJECTION OF FSH DISSOLVED IN POLYETHYLENE GLYCOL ON SUPEROVULATION RESPONSE IN KOREAN NATIVE COWS." Reproduction, Fertility and Development 21, no. 1 (2009): 243. http://dx.doi.org/10.1071/rdv21n1ab292.

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Superovulation in bovine is usually achieved after several FSH injection in a time-consuming protocol, and the half-life of FSH is very short. This study was carried out to assess the efficiency of embryo production after induction of superovulation with a single injection of FSH (Folltropin-V, Vetrepharm, Canada) dissolved in polyethylene glycol (PEG, 8000 MW, Sigma-Aldrich Corp., St. Louis, MO, USA) in Korean Native cows. Eighty-eight cows were randomly assigned to one of four groups. In Group 1 (control), cows were intramuscularly treated with twice-daily administration of 50 mg FSH for 4 d

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SHYAMSUNDER, Akshara, Tristan HARDY, Anusch YAZDANI, et al. "Higher Doses of FSH Used for Superovulation Do Not Adversely Affect Embryonic Ploidy: A Randomised Controlled Trial (Stimulation Resulting in Embryonic Aneuploidy Using Menopur (STREAM) Trial)." Fertility & Reproduction 04, no. 03n04 (2022): 142. http://dx.doi.org/10.1142/s2661318222740541.

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Background: High dose gonadotropin stimulation protocols may increase costs, patient discomfort, likelihood of ovarian hyper stimulation syndrome (OHSS), ovarian torsion and increased bleeding after multiple ovarian punctures. In addition, it is possible that high dose stimulation may result in impaired oocyte “quality” with adverse effect of embryonic ploidy. This may negate any benefits seen from a higher oocyte yield after high dose stimulation. Aim: To determine the proportion of euploid blastocysts resulting from higher versus lower dose ovarian stimulation protocols. Method: Multicentre

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Miyoshi, A., M. Sugawara, Y. Kaneda, H. Sekizawa, and O. Dochi. "193 Comparison of Superovulatory Responses to Single Subcutaneous FSH Injection and Twice-Daily Intramuscular FSH Injection Protocols in Japanese Black Cows." Reproduction, Fertility and Development 30, no. 1 (2018): 237. http://dx.doi.org/10.1071/rdv30n1ab193.

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The conventional superovulation treatment using follicle-stimulating hormone (FSH) comprises 2 intramuscular injections per day for 3 to 4 days. This conventional method requires frequent handling of donors—which may cause increasing stress in donors—and high labour costs. Therefore, to alleviate these issues, a treatment protocol using a single FSH injection under on-farm conditions is needed. The objective of this study was to evaluate the feasibility of the single subcutaneous FSH injection protocol (Sugawara et al. 2017 Reprod. Fertil. Dev. 29, 209), compared with with the traditional twic

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Gladenko, Svitlana. "Women have infertility with of high quality pathology of mammary glands." Perinatology and reproductology: from research to practice 3, no. 1 (2023): 80–84. https://doi.org/10.52705/2788-6190-2023-01-10.

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The objective: іncrease of efficiency of treatment of infertility for women with pathology of mammary glands on the basis of study of clinical and echographic, endocrinology and haemodynamic features and improvement of algorithm of auxiliary genesial technologies. Materials and methods. 90 women which were on treatment of infertility after different methods are plugged in research, including auxiliary genesial technologies. Researches carried stage-by-stage character: 1 the stage is forming of basic (n=60) and control groups (n=30) in accordance with a presence and treatment of pathology of ma

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