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1

Hillis, Graham S. "Cell surface markers in normal and diseased kidney." Thesis, University of Aberdeen, 1997. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU602001.

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Cell surface receptors such as adhesion molecules and connexins are involved in interactions between cells and their surroundings. They play important roles in the normal function of healthy tissues and in the responses of cells to injury. In many cases aberrant repair mechanisms are thought to result in disease and this thesis will assess the expression of cell adhesion molecules (principally the pi integrins) and the connexin43 gap junction protein in normal and diseased kidney The expression of pi integrins on normal human mesangial cells was localised using the alkaline phosphatase anti-al
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2

O'Malley, James. "Novel cell surface markers identify routes to iPS cells." Thesis, University of Edinburgh, 2014. http://hdl.handle.net/1842/8883.

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The generation of induced pluripotent stem cells (iPSCs) presents a challenge to normal developmental processes. The low efficiency and heterogeneity of most methods have hindered understanding of the precise molecular mechanisms promoting, and roadblocks preventing, efficient reprogramming. While several intermediate populations have been described, it has proved difficult to characterize the rare, asynchronous transition from these intermediate stages to iPSCs. The rapid expansion of a minor population of reprogrammed cells can also obscure investigation of relevant processes. Understanding
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3

Richardson, Kirsty. "Analysis of cell surface markers within immature bovine articular cartilage." Thesis, Cardiff University, 2011. http://orca.cf.ac.uk/17356/.

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Previous studies have shown that articular cartilage grows by apposition from the joint surface, driven by proliferation of a progenitor cell sub-population residing in the superficial zone. To date, there is no individual marker for this progenitor sub-population; however, markers located to mesenchymal stem cells have been identified in articular cartilage. Using immunofluorescence, this study demonstrated the localisation of the stem cell markers, CD44, CD49e, CD105 and CD166 to the superficial zone of bovine immature articular cartilage. CD29 and the developmental markers, Notch1, Delta1,
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4

Sutton, Catherine Anne. "Identifying novel cell surface markers for bone marrow stem cell sub-sets." Thesis, University of Bristol, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.557971.

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Osteoarthritis (OA) is a disease which affects hyaline cartilage within the joint and leads to severe pain for the patient. Chondrocytes within the cartilage of OA patients have a limited capability to repair lesions in the tissue and as a result, bone marrow stromal cells (BMSCs) which have the ability to differentiate into cartilage, are being investigated for cell- based therapies for OA. One restriction for the use of BMSCs in clinical trials is the rarity and heterogeneity of the starting population. It is therefore important to identify cell surface markers for BMSCs which produce a high
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5

Niu, Suli. "Quantitative Determination of Surface Markers on B-cell Chronic Lymphocytic Leukemia (CLL) Cells." Thèse, Université d'Ottawa / University of Ottawa, 2014. http://hdl.handle.net/10393/30982.

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To supplement and modify the diagnosis and clinical research of B-cell Chronic Lymphocytic Leukemia (B-CLL), a new method based on cell imaging and image processing was developed and applied to the B-CLL patient samples. The fluorophore-labelled leukemia cells were clearly visualized, reflecting the positive/negative expression of the corresponding surface markers and their distribution. Computer algorithms were devised and used to analyze a large number of images. The fluorescence intensity of the labelled antibodies on a given cell directly reflects the expression of the corresponding surfac
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6

Carvalho, Jose Joao. "Immunochemical and chromatographic methods for two anthropogenic markers of contamination in surface waters." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2011. http://dx.doi.org/10.18452/16420.

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Koffein (1,3,7-Trimethylxanthin) und Coprostanol (5beta-cholestan-3beta-ol) wurden im Berliner Oberflächenwasser nachgewiesen. Ihre Konzentrationen korrelierten mit dem Verunreinigungsgrad der Proben, was nahelegt, dass sie sich als Marker für menschliche Aktivität eignen. Bemerkenswerterweise wurde Koffein in jeder einzelnen Oberflächenwasserprobe oberhalb der Bestimmungsgrenze von 0,025 µg/L gefunden. Um Oberflächenwasserproben in größeren Serien zu untersuchen, war die Entwicklung zweier neuer Methoden erforderlich: ein Immunoassay, basierend auf einem monoklonalen Antikörper für Koffein u
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Zhou, Jerry. "Discovery and application of colorectal cancer protein markers for disease stratification." Thesis, The University of Sydney, 2013. http://hdl.handle.net/2123/10400.

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Colorectal cancer (CRC) is a major cause of cancer mortality. Whereas some patients respond well to therapy, others do not, and thus more precise methods of CRC stratification are needed. The intracellular protein expression from 28 CRC primary tumours and corresponding normal intestinal mucosa was analysed using saturation-DIGE/MS and Explorer antibody microarrays. Changes in protein abundance were identified at each stage of CRC. Proteins associated with proliferation, glycolysis, reduced adhesion, endoplasmic reticulum stress, angiogenesis, and response to hypoxia represent changes to CRC a
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8

Madden, Jacqueline. "Flow cytometric assessment of T cell activation in asthma." Thesis, University of Southampton, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.245048.

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9

Dunne, Jenny. "Human T lymphocyte cell surface antigens and their genes." Thesis, Open University, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.281609.

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10

Haworth, Kristina Marie OD MS. "Effects of Ultraviolet Radiation Exposure on Oxidative Stress Markers on the Human Ocular Surface." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1417447050.

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11

Kenny, Emma. "Peripheral CD4'+ T cell subsets involved in primary and secondary immune responses." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343045.

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12

Maddox, Jacquelyn R. Niyibizi Christopher. "Evaluation of putative cell surface markers that characterize human and murine adipose derived stem cells." [University Park, Pa.] : Pennsylvania State University, 2009. http://etda.libraries.psu.edu/theses/approved/WorldWideIndex/ETD-4509/index.html.

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13

Acero, Sánchez Josep Lluís. "Study of surface chemistry strategies to enhance the electrochemical detection of proteins and DNA markers." Doctoral thesis, Universitat Rovira i Virgili, 2017. http://hdl.handle.net/10803/461059.

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Els biosensors son dispositius analítics basats en la interacció específica entre un element biològic sensor i la seva molècula diana juntament amb un transductor per al processament de la senyal. Aquests dispositius tenen moltes aplicacions pràctiques en diferents camps d’investigació, des del diagnòstic mèdic a l’anàlisi mediambiental, i amb un gran potencial per a la seva comercialització. Tot i les grans expectatives, únicament hi ha uns pocs exemples de biosensors comercials, sent el mercat dominat principalment pels sensors de glucosa per gent amb diabetis, amb aproximadament un 85 % de
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ISHIGURO, NAOKI, HIROHITO MITSUYAMA, YOHEI ONO, et al. "Surface Markers and Gene Expression to Characterize the Differentiation of Monolayer Expanded Human Articular Chondrocytes." Nagoya University School of Medicine, 2013. http://hdl.handle.net/2237/17606.

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15

Horne, Gillian A. "Understanding the progression of CML through the regulation of self-renewal and cell surface markers." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8589/.

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16

Hoshina, Azusa. "Development of new method to enrich human iPSC-derived renal progenitors using cell surface markers." Kyoto University, 2018. http://hdl.handle.net/2433/235064.

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Supplementary information 追加(2019-09-30)<br>Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(医学)<br>甲第21344号<br>医博第4402号<br>新制||医||1031(附属図書館)<br>京都大学大学院医学研究科医学専攻<br>(主査)教授 柳田 素子, 教授 山下 潤, 教授 江藤 浩之<br>学位規則第4条第1項該当
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17

Cico, Alba. "Molecular mechanisms of normal erythropoiesis." Thesis, Sorbonne Paris Cité, 2017. http://www.theses.fr/2017USPCC311.

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Un être humain adulte produit environ deux millions d’érythrocytes par seconde, à travers un processus connu sous le nom d’érythropoïèse. L’érythropoïèse est contrôlée par une balance entre prolifération et différenciation finement régulée. L’expression des gènes impliqués dans ces deux processus distincts, est régulée extrinsèquement (cytokines) et intrinsèquement (microenvirennement métabolique, facteurs de transcription). Les facteurs de transcription, fonctionnent sous forme de complexes multiprotéiques et contrôlent l’activité transcriptionnelle des cellules. Parmi eux, le complexe LDB1 j
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18

Estes, Matthew D. "On-chip Cell Separator using Magnetic Bead-based Enrichment and Depletion of Various Cell Surface Markers." University of Cincinnati / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1242661265.

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19

Targa, Laurie. "Contribution to the study of mesenchymal stromal / stem cells heterogeneity, focus on surface markers and senescence." Thesis, Université de Lorraine, 2019. https://docnum.univ-lorraine.fr/ulprive/DDOC_T_2019_0353_TARGA.pdf.

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Les Cellules Stromales / Souches Mésenchymateuses (CSM) ont un grand potentiel pour de nombreuses applications. Elles sont les cellules les plus utilisées pour les essais cliniques développant des thérapies cellulaires. L’efficacité thérapeutique des CSM est influencée par leur amplification in vitro et d’autres facteurs tels que les paramètres liés au donneur de cellules. Pour améliorer les thérapies à base de CSM, cette étude a ciblé l’étude de leur hétérogénéité grâce à leurs marqueurs de surface, qui permettent de mutualiser la caractérisation des cellules et la possibilité de trier des ce
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20

Nagato, Masako. "Prospective characterization of neural stem cells by flow cytometry analysis using combination of the surface markers." Kyoto University, 2005. http://hdl.handle.net/2433/144466.

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21

Anastassiadis, Konstantinos, and Maria Rostovskaya. "Differential Expression of Surface Markers in Mouse Bone Marrow Mesenchymal Stromal Cell Subpopulations with Distinct Lineage Commitment." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-191602.

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Bone marrow mesenchymal stromal cells (BM MSCs) represent a heterogeneous population of progenitors with potential for generation of skeletal tissues. However the identity of BM MSC subpopulations is poorly defined mainly due to the absence of specific markers allowing in situ localization of those cells and isolation of pure cell types. Here, we aimed at characterization of surface markers in mouse BM MSCs and in their subsets with distinct differentiation potential. Using conditionally immortalized BM MSCs we performed a screening with 176 antibodies and high-throughput flow cytometry, and f
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22

Anastassiadis, Konstantinos, and Maria Rostovskaya. "Differential Expression of Surface Markers in Mouse Bone Marrow Mesenchymal Stromal Cell Subpopulations with Distinct Lineage Commitment." Public Library of Science, 2012. https://tud.qucosa.de/id/qucosa%3A29135.

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Bone marrow mesenchymal stromal cells (BM MSCs) represent a heterogeneous population of progenitors with potential for generation of skeletal tissues. However the identity of BM MSC subpopulations is poorly defined mainly due to the absence of specific markers allowing in situ localization of those cells and isolation of pure cell types. Here, we aimed at characterization of surface markers in mouse BM MSCs and in their subsets with distinct differentiation potential. Using conditionally immortalized BM MSCs we performed a screening with 176 antibodies and high-throughput flow cytometry, and f
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23

Grover, Vimal. "The use of soluble and surface TREM-1 as markers of Ventilator-associated pneumonia in Intensive Care." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/23996.

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Ventilator-associated pneumonia (VAP) is the commonest nosocomial infection in Intensive Care and is associated with significant morbidity and mortality. Biomarkers offer the potential to speed up diagnosis and differentiate pulmonary from nonpulmonary infection. We postulated that measurement of cell surface receptors in addition to soluble proteins, in dual sites (blood and BAL) and calculation of an index ratio of BAL / blood would increase the discriminative utility and differentiate pulmonary from non-pulmonary infection. Our body of work included paired blood and BALF obtained from 91 pa
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24

Corso, Christopher David. "Theoretical and experimental development of a ZnO-based laterally excited thickness shear mode acoustic wave immunosensor for cancer biomarker detection." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2008. http://hdl.handle.net/1853/24728.

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Thesis (Ph.D.)--Biomedical Engineering, Georgia Institute of Technology, 2008.<br>Committee Chair: William D Hunt; Committee Member: Bruno Frazier; Committee Member: Dale Edmondson; Committee Member: Marie Csete; Committee Member: Peter Edmonson; Committee Member: Ruth O'Regan
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25

Harutiun, Minas Nalbandian Geymonat. "Characterization of hiPSC-Derived Muscle Progenitors Reveals Distinctive Markers for Myogenic Cell Purification Toward Cell Therapy." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/265184.

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京都大学<br>新制・課程博士<br>博士(医学)<br>甲第23412号<br>医博第4757号<br>新制||医||1052(附属図書館)<br>京都大学大学院医学研究科医学専攻<br>(主査)特定拠点教授 妻木 範行, 教授 戸口田 淳也, 教授 松田 秀一<br>学位規則第4条第1項該当<br>Doctor of Medical Science<br>Kyoto University<br>DFAM
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26

Hjalmar, Viktoria. "Chronic leukemic B-cell disorders and trisomy 12 : a study of surface markers, protein expression and clinical course /." Stockholm, 2001. http://diss.kib.ki.se/2001/91-628-4664-7/.

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27

Mumprecht, Viviane Denise. "In vivo imaging of tumor- and inflammation-induced lymph node lymphangiogenesis and proteomic profiling for the identification of surface-accessible lymphatic markers /." [S.l.] : [s.n.], 2009. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=18414.

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28

Pais, Goyache Irene. "DEVELOPMENT OF A CHEMICAL FINGERPRINT FOR DETECTING UNTREATED HUMAN SEWAGE POLLUTION IN SURFACE WATER." Master's thesis, Temple University Libraries, 2015. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/360924.

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Civil Engineering<br>M.S.Env.E.<br>Untreated human sewage pollution in surface water is of concern because it contributes to the degradation of aquatic ecosystems and it could be a potential hazard to human health. Also, any pollution of surface water, which ultimately supplies drinking water, may affect the drinking water quality. Improper operation and maintenance of separate storm sewer systems are prominent contributors of untreated sewage to source waters, resulting from illicit connections, leakage of sewers, or cross-connections. This thesis studied anthropogenic markers to track untrea
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29

Liuba, Ioan. "Focal atrial tachycardia : Insights concerning the arrhythmogenic substrate based on analysis of intracardiac electrograms and inflammatory markers." Doctoral thesis, Linköping : Department of Medical and Health Sciences, Linköping University, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-20461.

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30

Wathen, Adam Daniel. "Acoustic wave biosensor arrays for the simultaneous detection of multiple cancer biomarkers." Diss., Georgia Institute of Technology, 2011. http://hdl.handle.net/1853/42717.

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The analysis and development of robust sensing platforms based on solidly-mounted ZnO bulk acoustic wave devices was proposed. The exploitation of acoustic energy trapping was investigated and demonstrated as a method to define active sensing areas on a substrate. In addition, a new "hybrid" acoustic mode experiencing acoustic energy trapping was studied theoretically and experimentally. This mode was used as an explanation of historical inconsistencies in observed thickness-shear mode velocities. Initial theoretical and experimental results suggest that this mode is a coupling of thicknes
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31

Carvalho, Jos´e João Dias [Verfasser], Ulrich [Akademischer Betreuer] Panne, Michael G. [Akademischer Betreuer] Weller, and Rudolf J. [Akademischer Betreuer] Schneider. "Immunochemical and chromatographic methods for two anthropogenic markers of contamination in surface waters : caffeine and coprostanol / Jos´e João Dias Carvalho. Gutachter: Ulrich Panne ; Michael G. Weller ; Rudolf J. Schneider." Berlin : Humboldt Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2011. http://d-nb.info/1018017690/34.

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32

VanCott, John Louis. "Protective immunity against transmissible gastroenteritis virus (TGEW) : enumeration of antibody-secreting cells and identification of mononuclear cell surface markers in systemic and mucosal lymphoid tissues of young pigs exposed to TGEV... /." The Ohio State University, 1993. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487842372895095.

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33

Ansari, Dominic O. "Raman-encoded nanoparticles for biomolecular detection and cancer diagnostics." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2008. http://hdl.handle.net/1853/26664.

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Thesis (Ph. D.)--Biomedical Engineering, Georgia Institute of Technology, 2009.<br>Committee Chair: Nie, Shuming; Committee Member: Parkos, Charles; Committee Member: Petros, John; Committee Member: Voit, Eberhard; Committee Member: Zhu, Cheng. Part of the SMARTech Electronic Thesis and Dissertation Collection.
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34

Chorvátová, Michaela. "Vliv elektrických pulzů na lidské krevní fagocyty." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2019. http://www.nusl.cz/ntk/nusl-401914.

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The phagocytic cells circulating in the bloodstream play a key role in both the defense of the body and the pathology of inflammatory diseases. Thus, targeting their functions has potential to modulate an immune response, especially during the inflammatory phase. This master's thesis was focused on the influence of electric pulses on the most abundant phagocyte population in human peripheral blood, namely neutrophils. The theoretical part describes the role of neutrophils in the development of the immune response and the effects of the electric field on various cells. Consequent part of the th
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35

Santos, Seiça Ana Filipa. "Infrared spectroscopic study of the conformational movements in membrane proteins from the respiratory chain by introducing a CN label in critical positions." Thesis, Strasbourg, 2019. http://www.theses.fr/2019STRAF064.

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Dans cette thèse 2, différentes bandes marqueurs en infrarouge de la protéine ont été étudiées, la ν(C=O) Asp/Glu entre 1730-1750 cm-1 et la ν(SC≡N) entre 2175-2120 cm-1 par spectroscopie infrarouge exaltée de surface. Les sondes infrarouges ont été introduites dans les protéines membranaires de la chaîne respiratoire. Ainsi les grands mouvements des domaines protéiques gouvernant les mécanismes catalytiques ont été contrôlés par les spectroscopies vibrationnelles à l'aide d’une réaction induite. Avant d'étudier les marqueurs infrarouges, il était nécessaire de comprendre, d’une part, l'influe
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36

Collier, Amanda. "Characterising the reprogramming dynamics between human pluripotent states." Thesis, University of Cambridge, 2019. https://www.repository.cam.ac.uk/handle/1810/287952.

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Human pluripotent stem cells (hPSCs) exist in multiple states of pluripotency, broadly categorised as naïve and primed states. These provide an important model to investigate the earliest stages of human embryonic development. Naïve cells can be obtained through primed-to-naïve reprogramming; however, there are no reliable methods to prospectively isolate unmodified naïve cells during this process. Moreover, the current isolation strategies are incompatible for enrichment of naïve hPSCs early during reprogramming. Consequently, we know very little about the temporal dynamics of transcript
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37

Chong, Goh Yaw. "Characterisation of a cell-surface marker of apoptosis." Thesis, University of Edinburgh, 2005. http://hdl.handle.net/1842/29663.

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The studies undertaken in this research project characterised as fully as possible the antigen identified by the monoclonal antibody BOB78. Earlier studies have linked BOB78 to the identification of apoptotic cells. The present project extended this finding by further studies utilising various antibody-based techniques on cancer-derived cell lines in different stages of apoptosis. The BOB78 antigen was confirmed to be present in normal blood cells and to be multi-lineage. BOB78 is normally expressed within the cytosol of nucleated blood cells, but absent in anucleated red blood cells which do
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Braunig, Patricia. "Desenvolvimento e caracterização de células-tronco mesenquimais derivadas do tecido adiposo e seu potencial de diferenciação." Universidade Federal de Santa Maria, 2016. http://repositorio.ufsm.br/handle/1/4127.

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Mesenchymal stem cells (MSCs) have demonstrated significant potential for clinical use due to their convenient isolation, lack of significant immunogenicity, lack of ethical controversy and their potential to differentiate into tissue-specific cell types. MSCs reside in almost all tissues including the adipose tissue. Adipose tissue has main advantages as wide distribution in the organism, suitable isolation and considerable amount of resident multipotent stem cells. Therefore, in this study, adipose tissue-derived mesenchymal stem cells (AT-MSCs) were isolated from BALB/c mice omentum and epi
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39

Detlefsen, Kai. "Equity derivatives markets." Doctoral thesis, Humboldt-Universität zu Berlin, Wirtschaftswissenschaftliche Fakultät, 2007. http://www.gbv.de/dms/zbw/561396701.pdf.

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Foguim, Tsombeng Francis. "Identification des marqueurs moléculaires impliqués dans la résistance de Plasmodium falciparum à la pipéraquine." Thesis, Aix-Marseille, 2019. http://www.theses.fr/2019AIXM0240.

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La résistance à la pipéraquine et les échecs cliniques à la dihydroartémisinine-pipéraquine en Asie du Sud Est alertent sur les risques pour l'Afrique. Le marqueur moléculaire de l'artémisinine (mutations K13) permet d'étudier la résistance dans cette région. Pour la pipéraquine, l'amplification du nombre de copies du gène de la plasmepsin 2 (pfpm2) a été identifié comme potentiel marqueur de résistance en Asie. Par ailleurs des mutations sur le gène pfcrt étaient aussi associées à la résistance à la pipéraquine. En Afrique où ce médicament est actuellement utilisé, il était intéressant d'étud
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Cairns, A. P. "Leukocyte surface marker expression of relevance to apoptotic cell clearance in systemic lupus erythematosus." Thesis, Queen's University Belfast, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391114.

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42

Zanchini, Giulia. "Stochastic local volatility model for fx markets." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2014. http://amslaurea.unibo.it/7685/.

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Questa tesi verte sullo studio di un modello a volatilità stocastica e locale, utilizzato per valutare opzioni esotiche nei mercati dei cambio. La difficoltà nell'implementare un modello di tal tipo risiede nella calibrazione della leverage surface e uno degli scopi principali di questo lavoro è quello di mostrarne la procedura.
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Barkhagen, Mathias. "Optimal Decisions in the Equity Index Derivatives Markets Using Option Implied Information." Doctoral thesis, Linköpings universitet, Produktionsekonomi, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-117106.

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This dissertation is centered around two comprehensive themes: the extraction of information embedded in equity index option prices, and how to use this information in order to be able to make optimal decisions in the equity index option markets. These problems are important for decision makers in the equity index options markets, since they are continuously faced with making decisions under uncertainty given observed market prices. The methods developed in this dissertation provide robust tools that can be used by practitioners in order to improve the quality of the decisions that they make.
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Rato, Carla Cristina Pereira Salgueiro Catarino. "The life marker chip : potential use of aptamers against small molecules and consideration of instrument planetary protection." Thesis, Cranfield University, 2013. http://dspace.lib.cranfield.ac.uk/handle/1826/8272.

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The Life Marker Chip (LMC) instrument was developed with the aim to detect evidence of life on Mars. The detection was based on an inhibition immunoassay. In this work aptamers were evaluated as potential alternative to antibodies for the LMC. Aptamers were synthetic oligonucleotides able to bind specifically with high affinity to a wide range of target molecules, and have been also integrated as bioreceptors in several detection instruments. The generation of new aptamers against two small molecules using the FluMag-SELEX method was tested and was verified the adaptability of pre-existing apt
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Petkova, Neli [Verfasser], and Stefan [Akademischer Betreuer] Stevanovic. "A surface marker study to identify epithelial and mesenchymal stromal progenitor cells in human prostate / Neli Petkova ; Betreuer: Stefan Stevanovic." Tübingen : Universitätsbibliothek Tübingen, 2014. http://d-nb.info/1196877300/34.

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46

Yang, Zhugen. "3D-Microstructured Protein Chip for Cancer Diagnosis." Phd thesis, Ecole Centrale de Lyon, 2012. http://tel.archives-ouvertes.fr/tel-00780192.

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Protein microarrays are becoming powerful tools to screen and identify tumor markers for cancer diagnosis, because of the multiplex detection and minute volume of sample requirement. Due to the diversity and variation in different cancers, no single tumor marker is sensitive and specific enough to meet strict diagnostic criteria. Therefore, a combination of tumor markers is required to increase sensitivity and to establish distinct patterns to increase specificity. To obtain reliable tests, the development of reproducible surface chemistry and immobilization procedure are crucial steps in the
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Ranathunga, Arachchige Ranga Prabodanie. "A Market Mechanism for the Optimal Control of Groundwater and Surface Water Pollution from Nitrates." Thesis, University of Canterbury. Management, 2010. http://hdl.handle.net/10092/5144.

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Nitrate discharges from diffuse agricultural sources have long term effects on groundwater and surface water quality. Market-based instruments have been proposed as a means of balancing the demand for nitrate intensive farming and the capacity of the natural water bodies to dilute nitrates. Trading is complicated by the dispersed, delayed, and protracted effects of diffuse sources. Market mechanisms proposed to date have failed to incorporate these physical characteristics of nitrate pollution correctly. We propose a new market mechanism for allocating and pricing nitrate discharge permits, b
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48

Kirlangic, Ozgur Ulas. "Generation Of Surface Waves Due To Sudden Movements At The Sea Bottom." Master's thesis, METU, 2004. http://etd.lib.metu.edu.tr/upload/12604968/index.pdf.

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A mathematical model is developed for investigating time dependent surface deformations of a hydrostatic water volume, when it is subjected to a sudden partial collapse or rise of the sea bottom. The model solves two-dimensional Navier-Stokes Equations on a vertical plane numerically by using Marker and Cell Method (MAC) for viscous and compressible fluid including all the nonlinear effects in the solution. For demonstration, a vertical motion was given to a section in a hypothetical reservoir bed within a short time period and the resulting velocity and pressure fields and the surface profi
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Gyamfi-Yeboah, Frank. "An Examination of the Information Content of Funds from Operations (FFO) Using Polynomial Regression and Response Surface Methodology." Digital Archive @ GSU, 2010. http://digitalarchive.gsu.edu/real_estate_diss/7.

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I examine the market reaction to the announcement of FFO by REITs using abnormal trading volume as a gauge of investors’ reaction. I also address the question of whether FFO provides more useful information to investors than net income. Lastly, I examine whether the quality of private information among traders prior to the announcement of FFO affects the level of abnormal trading volume. Using three different specifications, I find that even though the announcement of FFO leads to abnormal trading, there is no association between the level of abnormal trading volume and the size of the surpris
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50

Landers, Emilee Kathleen. "Rapid Compositional Assessment of Tomato Fruit by Using Portable Mid-Infrared Spectroscopy." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1417539506.

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