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Journal articles on the topic 'Suspended Microchannel Resonator'

Author: Grafiati

Published: 14 March 2023

Last updated: 31 July 2025

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1

Vakilzadeh, Mohsen, Ramin Vatankhah, and Mohammad Eghtesad. "Tracking control of suspended microchannel resonators based on Krylov model order reduction method." Journal of Vibration and Control 25, no. 5 (2018): 1019–30. http://dx.doi.org/10.1177/1077546318809609.

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In this paper, trajectory tracking control of suspended microchannel resonators (SMRs) is studied. A finite element procedure based on modified strain gradient theory will be used to model the SMR. Finite element methods usually lead to a model with a relatively high number of degrees of freedom. Thus, first, we will utilize the second order Krylov subspace method based on multi-moment matching to obtain a second order bilinear reduced system. Then, an output feedback controller and an optimal controller which take much less computation time and effort will be designed for the reduced system.

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2

Martín-Pérez, Alberto, Daniel Ramos, Javier Tamayo, and Montserrat Calleja. "Nanomechanical Molecular Mass Sensing Using Suspended Microchannel Resonators." Sensors 21, no. 10 (2021): 3337. http://dx.doi.org/10.3390/s21103337.

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In this work we study the different phenomena taking place when a hydrostatic pressure is applied in the inner fluid of a suspended microchannel resonator. Additionally to pressure-induced stiffness terms, we have theoretically predicted and experimentally demonstrated that the pressure also induces mass effects which depend on both the applied pressure and the fluid properties. We have used these phenomena to characterize the frequency response of the device as a function of the fluid compressibility and molecular masses of different fluids ranging from liquids to gases. The proposed device i

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3

Zakeri, Manizhe, and Seyed Mahmoud Seyedi Sahebari. "Modeling and simulation of a suspended microchannel resonator nano-sensor." Microsystem Technologies 24, no. 2 (2017): 1153–66. http://dx.doi.org/10.1007/s00542-017-3478-6.

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4

Martín-Pérez, Ramos, Tamayo, and Calleja. "Coherent Optical Transduction of Suspended Microcapillary Resonators for Multi-Parameter Sensing Applications." Sensors 19, no. 23 (2019): 5069. http://dx.doi.org/10.3390/s19235069.

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Characterization of micro and nanoparticle mass has become increasingly relevant in a wide range of fields, from materials science to drug development. The real-time analysis of complex mixtures in liquids demands very high mass sensitivity and high throughput. One of the most promising approaches for real-time measurements in liquid, with an excellent mass sensitivity, is the use of suspended microchannel resonators, where a carrier liquid containing the analytes flows through a nanomechanical resonator while tracking its resonance frequency shift. To this end, an extremely sensitive mechanic

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5

Yan, Han, Wen-Ming Zhang, Hui-Ming Jiang, and Kai-Ming Hu. "Pull-In Effect of Suspended Microchannel Resonator Sensor Subjected to Electrostatic Actuation." Sensors 17, no. 12 (2017): 114. http://dx.doi.org/10.3390/s17010114.

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6

Folzer, Emilien, Tarik A. Khan, Roland Schmidt, et al. "Determination of the Density of Protein Particles Using a Suspended Microchannel Resonator." Journal of Pharmaceutical Sciences 104, no. 12 (2015): 4034–40. http://dx.doi.org/10.1002/jps.24635.

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7

Son, Sungmin, Joon Ho Kang, Seungeun Oh, Marc W. Kirschner, T. J. Mitchison, and Scott Manalis. "Resonant microchannel volume and mass measurements show that suspended cells swell during mitosis." Journal of Cell Biology 211, no. 4 (2015): 757–63. http://dx.doi.org/10.1083/jcb.201505058.

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Osmotic regulation of intracellular water during mitosis is poorly understood because methods for monitoring relevant cellular physical properties with sufficient precision have been limited. Here we use a suspended microchannel resonator to monitor the volume and density of single cells in suspension with a precision of 1% and 0.03%, respectively. We find that for transformed murine lymphocytic leukemia and mouse pro–B cell lymphoid cell lines, mitotic cells reversibly increase their volume by more than 10% and decrease their density by 0.4% over a 20-min period. This response is correlated w

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8

Godin, Michel, Andrea K. Bryan, Thomas P. Burg, Ken Babcock, and Scott R. Manalis. "Measuring the mass, density, and size of particles and cells using a suspended microchannel resonator." Applied Physics Letters 91, no. 12 (2007): 123121. http://dx.doi.org/10.1063/1.2789694.

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9

Khan, M. F., S. Schmid, P. E. Larsen, et al. "Online measurement of mass density and viscosity of pL fluid samples with suspended microchannel resonator." Sensors and Actuators B: Chemical 185 (August 2013): 456–61. http://dx.doi.org/10.1016/j.snb.2013.04.095.

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10

Stockslager, Max A., Selim Olcum, Scott M. Knudsen, et al. "Rapid and high-precision sizing of single particles using parallel suspended microchannel resonator arrays and deconvolution." Review of Scientific Instruments 90, no. 8 (2019): 085004. http://dx.doi.org/10.1063/1.5100861.

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11

Dextras, Philip, Thomas P. Burg, and Scott R. Manalis. "Integrated Measurement of the Mass and Surface Charge of Discrete Microparticles Using a Suspended Microchannel Resonator." Analytical Chemistry 81, no. 11 (2009): 4517–23. http://dx.doi.org/10.1021/ac9005149.

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12

Accoto, Celso, Antonio Qualtieri, Ferruccio Pisanello, et al. "Two-Photon Polymerization Lithography and Laser Doppler Vibrometry of a SU-8-Based Suspended Microchannel Resonator." Journal of Microelectromechanical Systems 24, no. 4 (2015): 1038–42. http://dx.doi.org/10.1109/jmems.2014.2376986.

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13

Reza Nejadnik, M., and Wim Jiskoot. "Measurement of the Average Mass of Proteins Adsorbed to a Nanoparticle by Using a Suspended Microchannel Resonator." Journal of Pharmaceutical Sciences 104, no. 2 (2015): 698–704. http://dx.doi.org/10.1002/jps.24206.

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14

Patel, Ankit R., Doris Lau, and Jun Liu. "Quantification and Characterization of Micrometer and Submicrometer Subvisible Particles in Protein Therapeutics by Use of a Suspended Microchannel Resonator." Analytical Chemistry 84, no. 15 (2012): 6833–40. http://dx.doi.org/10.1021/ac300976g.

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15

MOTTAGHI, Mehrdad, and Habib B. GHAVIFEKR. "P-BIO-05 OPTIMIZATION OF SUSPENDED MICROCHANNEL RESONATOR WITH INTEGRATED PIEZORESISTIVE READOUT AS A HIGH-Q FACTOR BIOMOLECULAR RECOGNITION SYSTEM IN AQUEOUS ENVIROMENT(Bio-medical Equipments,Technical Program of Poster Session)." Proceedings of JSME-IIP/ASME-ISPS Joint Conference on Micromechatronics for Information and Precision Equipment : IIP/ISPS joint MIPE 2009 (2009): 397–98. http://dx.doi.org/10.1299/jsmemipe.2009.397.

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16

Lewis, Christina L., Caelli C. Craig, and Andre G. Senecal. "Mass and Density Measurements of Live and Dead Gram-Negative and Gram-Positive Bacterial Populations." Applied and Environmental Microbiology 80, no. 12 (2014): 3622–31. http://dx.doi.org/10.1128/aem.00117-14.

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ABSTRACTMonitoring cell growth and measuring physical features of food-borne pathogenic bacteria are important for better understanding the conditions under which these organisms survive and proliferate. To address this challenge, buoyant masses of live and deadEscherichia coliO157:H7 andListeria innocuawere measured using Archimedes, a commercially available suspended microchannel resonator (SMR). Cell growth was monitored with Archimedes by observing increased cell concentration and buoyant mass values of live growing bacteria. These growth data were compared to optical density measurements

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17

Knudsen, Scott M., Nathan Cermak, Francisco Feijó Delgado, Barbara Setlow, Peter Setlow, and Scott R. Manalis. "Water and Small-Molecule Permeation of Dormant Bacillus subtilis Spores." Journal of Bacteriology 198, no. 1 (2015): 168–77. http://dx.doi.org/10.1128/jb.00435-15.

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ABSTRACTWe use a suspended microchannel resonator to characterize the water and small-molecule permeability ofBacillus subtilisspores based on spores' buoyant mass in different solutions. Consistent with previous results, we found that the spore coat is not a significant barrier to small molecules, and the extent to which small molecules may enter the spore is size dependent. We have developed a method to directly observe the exchange kinetics of intraspore water with deuterium oxide, and we applied this method to wild-type spores and a panel of congenic mutants with deficiencies in the assemb

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18

Lee, J., R. Chunara, W. Shen, et al. "Suspended microchannel resonators with piezoresistive sensors." Lab Chip 11, no. 4 (2011): 645–51. http://dx.doi.org/10.1039/c0lc00447b.

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19

Burg, T. P., and S. R. Manalis. "Suspended microchannel resonators for biomolecular detection." Applied Physics Letters 83, no. 13 (2003): 2698–700. http://dx.doi.org/10.1063/1.1611625.

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20

Son, Sungmin, William H. Grover, Thomas P. Burg, and Scott R. Manalis. "Suspended Microchannel Resonators for Ultralow Volume Universal Detection." Analytical Chemistry 80, no. 12 (2008): 4757–60. http://dx.doi.org/10.1021/ac800307a.

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21

Lee, I., K. Park, and J. Lee. "Note: Precision viscosity measurement using suspended microchannel resonators." Review of Scientific Instruments 83, no. 11 (2012): 116106. http://dx.doi.org/10.1063/1.4768245.

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22

De Pastina, A., D. Maillard, and L. G. Villanueva. "Fabrication of suspended microchannel resonators with integrated piezoelectric transduction." Microelectronic Engineering 192 (May 2018): 83–87. http://dx.doi.org/10.1016/j.mee.2018.02.011.

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23

Wang, Yu, Mario Matteo Modena, Mitja Platen, Iwan Alexander Taco Schaap, and Thomas Peter Burg. "Label-Free Measurement of Amyloid Elongation by Suspended Microchannel Resonators." Analytical Chemistry 87, no. 3 (2015): 1821–28. http://dx.doi.org/10.1021/ac503845f.

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24

Calmo, Roberta, Andrea Lovera, Stefano Stassi, et al. "Monolithic glass suspended microchannel resonators for enhanced mass sensing of liquids." Sensors and Actuators B: Chemical 283 (March 2019): 298–303. http://dx.doi.org/10.1016/j.snb.2018.12.019.

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25

von Muhlen, Marcio G., Norman D. Brault, Scott M. Knudsen, Shaoyi Jiang, and Scott R. Manalis. "Label-Free Biomarker Sensing in Undiluted Serum with Suspended Microchannel Resonators." Analytical Chemistry 82, no. 5 (2010): 1905–10. http://dx.doi.org/10.1021/ac9027356.

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26

Huang, Kuan-Rong, Jeng-Shian Chang, Sheng D. Chao, and Kuang-Chong Wu. "Beam model and three dimensional numerical simulations on suspended microchannel resonators." AIP Advances 2, no. 4 (2012): 042176. http://dx.doi.org/10.1063/1.4770321.

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27

Yan, Han, Wen-Ming Zhang, Hui-Ming Jiang, et al. "A measurement criterion for accurate mass detection using vibrating suspended microchannel resonators." Journal of Sound and Vibration 403 (September 2017): 1–20. http://dx.doi.org/10.1016/j.jsv.2017.05.030.

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28

Bryan, Andrea K., Vivian C. Hecht, Wenjiang Shen, Kristofor Payer, William H. Grover, and Scott R. Manalis. "Measuring single cell mass, volume, and density with dual suspended microchannel resonators." Lab Chip 14, no. 3 (2014): 569–76. http://dx.doi.org/10.1039/c3lc51022k.

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29

Toda, Masaya, Tomoyuki Otake, Hidetoshi Miyashita, Yusuke Kawai, and Takahito Ono. "Suspended bimaterial microchannel resonators for thermal sensing of local heat generation in liquid." Microsystem Technologies 19, no. 7 (2012): 1049–54. http://dx.doi.org/10.1007/s00542-012-1698-3.

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30

Arlett, J. L., and M. L. Roukes. "Ultimate and practical limits of fluid-based mass detection with suspended microchannel resonators." Journal of Applied Physics 108, no. 8 (2010): 084701. http://dx.doi.org/10.1063/1.3475151.

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31

Yun, Minhyuk, Il Lee, Sangmin Jeon, and Jungchul Lee. "Facile Phase Transition Measurements for Nanogram Level Liquid Samples Using Suspended Microchannel Resonators." IEEE Sensors Journal 14, no. 3 (2014): 781–85. http://dx.doi.org/10.1109/jsen.2013.2287887.

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32

Modena, Mario M., Yu Wang, Dietmar Riedel, and Thomas P. Burg. "Resolution enhancement of suspended microchannel resonators for weighing of biomolecular complexes in solution." Lab Chip 14, no. 2 (2014): 342–50. http://dx.doi.org/10.1039/c3lc51058a.

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33

Vakilzadeh, Mohsen, Ramin Vatankhah, and Mohammad Eghtesad. "Dynamics and vibration analysis of suspended microchannel resonators based on strain gradient theory." Microsystem Technologies 24, no. 4 (2017): 1995–2005. http://dx.doi.org/10.1007/s00542-017-3596-1.

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34

Hu, Ke, Pan Wu, Lin Wang, Hu-Liang Dai, and Qin Qian. "Vibration analysis of suspended microchannel resonators characterized as cantilevered micropipes conveying fluid and nanoparticle." Microsystem Technologies 25, no. 1 (2018): 197–210. http://dx.doi.org/10.1007/s00542-018-3949-4.

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35

Lee, Il, Keunhan Park, and Jungchul Lee. "Precision density and volume contraction measurements of ethanol–water binary mixtures using suspended microchannel resonators." Sensors and Actuators A: Physical 194 (May 2013): 62–66. http://dx.doi.org/10.1016/j.sna.2013.01.046.

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36

Zhang, Wen-Ming, Han Yan, Hui-Ming Jiang, Kai-Ming Hu, Zhi-Ke Peng, and Guang Meng. "Dynamics of suspended microchannel resonators conveying opposite internal fluid flow: Stability, frequency shift and energy dissipation." Journal of Sound and Vibration 368 (April 2016): 103–20. http://dx.doi.org/10.1016/j.jsv.2016.01.029.

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37

Lee, Jungchul, and Juhee Ko. "(Invited) Hyper-Multimodal Sensing with Heater-Integrated Fluidic Resonators." ECS Meeting Abstracts MA2024-02, no. 64 (2024): 4304. https://doi.org/10.1149/ma2024-02644304mtgabs.

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Mechanical resonators with embedded fluidic channels (hereafter referred to as fluidic resonators), known as suspended micro/nanochannel resonators (SMRs or SNRs) [1, 2], allow precise and sensitive measurements of single micro/nanoparticles or single cells in transit, adsorbed biomolecules and liquid analytes. To date, the majority of studies using fluidic resonators have been performed at a fixed steady-state temperature close to room temperature, since temperature modulation inevitably changes the resonance frequency of the fluidic resonators, one of the key measurement variables. To mainta

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38

Mu, Luye, Joon Ho Kang, Selim Olcum, et al. "Mass measurements during lymphocytic leukemia cell polyploidization decouple cell cycle- and cell size-dependent growth." Proceedings of the National Academy of Sciences 117, no. 27 (2020): 15659–65. http://dx.doi.org/10.1073/pnas.1922197117.

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Cell size is believed to influence cell growth and metabolism. Consistently, several studies have revealed that large cells have lower mass accumulation rates per unit mass (i.e., growth efficiency) than intermediate-sized cells in the same population. Size-dependent growth is commonly attributed to transport limitations, such as increased diffusion timescales and decreased surface-to-volume ratio. However, separating cell size- and cell cycle-dependent growth is challenging. To address this, we monitored growth efficiency of pseudodiploid mouse lymphocytic leukemia cells during normal prolife

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39

Gross-Rother, Julia, Michaela Blech, Eduard Preis, Udo Bakowsky, and Patrick Garidel. "Particle Detection and Characterization for Biopharmaceutical Applications: Current Principles of Established and Alternative Techniques." Pharmaceutics 12, no. 11 (2020): 1112. http://dx.doi.org/10.3390/pharmaceutics12111112.

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Detection and characterization of particles in the visible and subvisible size range is critical in many fields of industrial research. Commercial particle analysis systems have proliferated over the last decade. Despite that growth, most systems continue to be based on well-established principles, and only a handful of new approaches have emerged. Identifying the right particle-analysis approach remains a challenge in research and development. The choice depends on each individual application, the sample, and the information the operator needs to obtain. In biopharmaceutical applications, par

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40

Yan, Han, Wen-Ming Zhang, Hui-Ming Jiang, Kai-Ming Hu, Zhi-Ke Peng, and Guang Meng. "Relative Vibration of Suspended Particles With Respect to Microchannel Resonators and Its Effect on the Mass Measurement." Journal of Vibration and Acoustics 141, no. 4 (2019). http://dx.doi.org/10.1115/1.4042937.

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In this work, the three-dimensional fluid–solid interaction vibration of particle in the oscillating resonator and its effect on the dynamic characteristics are analyzed and discussed. It demonstrates that the displacement of a particle is composed of two components, one is in phase with the acceleration of resonator and the other is out of phase. The former is responsible for the added mass effect and the latter results in a small damping. A modified measurement principle for detecting the buoyant mass is then presented by considering the in-phase component. The three-dimensional (3D) fluid–s

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41

Daryani, Mehdi Mollaie, Tomás Manzaneque, Jia Wei, and Murali Krishna Ghatkesar. "Measuring nanoparticles in liquid with attogram resolution using a microfabricated glass suspended microchannel resonator." Microsystems & Nanoengineering 8, no. 1 (2022). http://dx.doi.org/10.1038/s41378-022-00425-8.

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AbstractThe use of nanoparticles has been growing in various industrial fields, and concerns about their effects on health and the environment have been increasing. Hence, characterization techniques for nanoparticles are essential. Here, we present a silicon dioxide microfabricated suspended microchannel resonator (SMR) to measure the mass and concentration of nanoparticles in a liquid as they flow. We measured the mass detection limits of the device using laser Doppler vibrometry. This limit reached a minimum of 377 ag that correspond to a 34 nm diameter gold nanoparticle or a 243 nm diamete

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42

Sharma, Samridh, and Saurabh Arun Chandorkar. "Flow-induced frequency shifts in suspended microchannel resonators with ultra-thin walls and large hydraulic diameter." Journal of Applied Physics 136, no. 22 (2024). https://doi.org/10.1063/5.0230843.

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A suspended microchannel resonator (SMR) is an unconventionally designed microelectromechanical system mass sensor that allows internal fluid flow in its suspended structure. This device is operated at its resonance conditions and registers a frequency shift corresponding to the mass flowing through the channel. Presented here is a dynamic SMR fluid–structure phenomenon that has not been reported to date. SMR devices were fabricated with ultra-thin walls and large hydraulic diameter using thermo-compression wafer bonding, and optical characterization of these SMRs with internal fluid flow usin

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43

Funayama, Keita, Atsushi Miura, Fumihito Arai, and Hiroya Tanaka. "Silicon-Based Suspended Microchannel Resonator Developed Using Au Thermal Diffusion Bonding for Mass Sensing of Biomaterials." Journal of Microelectromechanical Systems, 2024, 1–8. http://dx.doi.org/10.1109/jmems.2024.3352835.

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44

Miettinen, Teemu P., Joon Ho Kang, Lucy F. Yang, and Scott R. Manalis. "Mammalian cell growth dynamics in mitosis." eLife 8 (May 7, 2019). http://dx.doi.org/10.7554/elife.44700.

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The extent and dynamics of animal cell biomass accumulation during mitosis are unknown, primarily because growth has not been quantified with sufficient precision and temporal resolution. Using the suspended microchannel resonator and protein synthesis assays, we quantify mass accumulation and translation rates between mitotic stages on a single-cell level. For various animal cell types, growth rates in prophase are commensurate with or higher than interphase growth rates. Growth is only stopped as cells approach metaphase-to-anaphase transition and growth resumes in late cytokinesis. Mitotic

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45

Ko, Juhee, Jaewoo Jeong, Sukbom Son, and Jungchul Lee. "Cellular and biomolecular detection based on suspended microchannel resonators." Biomedical Engineering Letters, September 12, 2021. http://dx.doi.org/10.1007/s13534-021-00207-7.

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46

"Unravelling the secrets of the cell with suspended microchannel resonators." Research Outreach, no. 110 (November 7, 2019): 42–45. http://dx.doi.org/10.32907/ro-110-4245.

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47

Maillard, Damien, Annalisa De Pastina, Amir Musa Abazari, and Luis Guillermo Villanueva. "Avoiding transduction-induced heating in suspended microchannel resonators using piezoelectricity." Microsystems & Nanoengineering 7, no. 1 (2021). http://dx.doi.org/10.1038/s41378-021-00254-1.

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AbstractCalorimetry of single biological entities remains elusive. Suspended microchannel resonators (SMRs) offer excellent performance for real-time detection of various analytes and could hold the key to unlocking pico-calorimetry experiments. However, the typical readout techniques for SMRs are optical-based, and significant heat is dissipated in the sensor, altering the measurement and worsening the frequency noise. In this manuscript, we demonstrate for the first time full on-chip piezoelectric transduction of SMRs on which we focus a laser Doppler vibrometer to analyze its effect. We dem

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48

Martín-Pérez, Alberto, and Daniel Ramos. "Nanomechanical hydrodynamic force sensing using suspended microfluidic channels." Microsystems & Nanoengineering 9, no. 1 (2023). http://dx.doi.org/10.1038/s41378-023-00531-1.

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AbstractMicrofluidics has demonstrated high versatility in the analysis of in-flow particles and can even achieve mechanical properties measurements of biological cells by applying hydrodynamic forces. However, there is currently no available technique that enables the direct measurement and tracking of these hydrodynamic forces acting on a flowing particle. In this work, we introduce a novel method for the direct measurement of the hydrodynamic force actuating on an in-flow particle based on the analysis of the induced resonance changes of suspended microchannel resonators (SMRs). This hydrod

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49

Ko, Juhee, Jaewoo Jeong, Sukbom Son, and Jungchul Lee. "Correction to: Cellular and biomolecular detection based on suspended microchannel resonators." Biomedical Engineering Letters, April 5, 2022. http://dx.doi.org/10.1007/s13534-022-00222-2.

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50

Vakilzadeh, Mohsen, Ramin Vatankhah, and Mohammad Eghtesad. "Investigation of dynamic pull-in instability of suspended microchannel resonators using homotopy analysis method." Journal of the Brazilian Society of Mechanical Sciences and Engineering 43, no. 6 (2021). http://dx.doi.org/10.1007/s40430-021-03028-y.

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