Academic literature on the topic 'Sustained-release drug delivery'

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Journal articles on the topic "Sustained-release drug delivery"

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Mandhar, Piyush, and Gayitri Joshi. "Development of Sustained Release Drug Delivery System: A Review." Asian Pacific Journal of Health Sciences 2, no. 1 (2015): 179–85. http://dx.doi.org/10.21276/apjhs.2015.2.1.31.

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BHADORIYA, ABHILASHA, and TRUPTI SHUKLA. "A CONCISE REVIEW ON SPANSULES: A NEW METHOD OF DRUG DELIVERY." Current Research in Pharmaceutical Sciences 13, no. 1 (2023): 21–26. http://dx.doi.org/10.24092/crps.2023.130102.

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Spansules are considered as an Advanced Drug Delivery System because they allow for controlled and sustained release of medication over an extended period of time. This type of delivery system can provide a constant plasma drug concentration over a wide range of time, which can improve treatment outcomes and reduce the risk of side effects. In addition to providing sustained release, Spansules can also be used to deliver multiple drugs in a single dosage form. The multi-drug regimen capability of Spansules is also beneficial, as it allows for the delivery of multiple drugs in a single dosage f
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Menkudale, Amruta, Pankaj Khuspe, Kishor Otari, Manisha Khemnar, and Vaishali Kulkarni. "An Updated Review on Applications of Natural Polymers in Sustained Release Drug Delivery System." Journal of Advances in Pharmacy Practices (e-ISSN: 2582-4465) 2, no. 1 (2020): 45–49. https://doi.org/10.5281/zenodo.3674633.

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<em>Sustained release drug delivery system is area of interest for formulation scientists in pharmaceutical industry because of advantage of administering a single dose of a drug that is released for an extended period of time instead of numerous doses. SDDS have various advantages like it optimize biopharmaceutical, pharmacokinetic and pharmacodynamic properties of drug in order to increase its use, reduce adverse effects, cure the disease, decrease the frequency of administration and thus, increase the patient compliance, increase safety margin of potent drugs, reduce healthcare costs etc. T
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Ankit, Singh* Rajesh Gour** &. Akhlesh Kumar Singhai***. "MODIFIED RELEASE OF MEDICATION DELIVERY: A REVIEW." International Journal of Scientific Research and Modern Education (IJSRME) 8, no. 1 (2023): 33–41. https://doi.org/10.5281/zenodo.7806086.

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In terms of drug delivery methods, the oral route is the most popular. However, the traditional dosage form has a few drawbacks that could be fixed by altering the current dosage form. A regulated and sustained drug delivery system prolongs the duration of action by slowing the drug&#39;s release rate and maintaining a consistent plasma drug concentration. The matrix tablet is a crucial tool among the numerous formulation options for sustained release tablets. This makes issues like poor patient compliance, multiple doses, and see-saw oscillations simply manageable. A number of hydrophilic or
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Muni, Raja Lakshmi K* Naseema Shaik Lavanya E. Venkata Rao Gadde. "Formulation And Evaluation of Sustained Release Matrix Tablets – A Review." Int. J. in Pharm. Sci. 1, no. 7 (2023): 170–81. https://doi.org/10.5281/zenodo.8114751.

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Oral drug delivery is still the finest and most popular method for administering pharmaceuticals via the internal route. Sustained release is also a good option for reducing adverse effect of drugs and boosting its therapeutic potency. The fundamental ideas of sustained drug delivery system optimise a variety of factors, such as a drugs pharmaceutical, pharmacokinetic and pharmacodynamic properties in order to increase therapeutic efficacy, minimise side effects and make disease cure simple. The major goal of this review is to provide comprehensive information about sustained release dose and
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Rajput, Rajesh, K. M. K. Prasanna Kumar, D. S. Arya, et al. "Osmotic controlled drug delivery system (OSMO technology) and its impact on diabetes care." International Journal of Research in Medical Sciences 9, no. 1 (2020): 303. http://dx.doi.org/10.18203/2320-6012.ijrms20205861.

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Recently, focus on the development of controlled release drug delivery system has increased, as existing drugs exhibit certain pharmacokinetic limitations. The major goal of designing sustained release formulations is to improve the drug performance by prolonged duration of drug action, decreased frequency of dosing and reduced side effects by using smallest quantity of drug administered by the most suitable route. Osmotic-controlled release oral delivery system (OSMO technology) is the most promising strategy based system for sustained delivery of drug. Drug can be delivered in a controlled m
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Prajapat, Priyanka, Dilip Agrawal, and Gaurav Bhaduka. "A brief overview of sustained released drug delivery system." Journal of Applied Pharmaceutical Research 10, no. 3 (2022): 05–11. http://dx.doi.org/10.18231/j.joapr.2022.10.3.5.11.

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The most popular and patient-friendly method of drug administration is often thought to be the oral route of administration. Compared to conventional release formulations, advancements in formulation technology, including modified release dosage forms or sustained release oral dosage forms, have been extensively accepted. A sustained release dosage form provides a prolonged release of the drug over an extended period, thereby giving better patient compliance and enhanced bioavailability. Sustain release systems are considered a wiser approach for drugs with short half-lives requiring repeated
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Sonali, S. Sonawane* Vikas B. Wamne. "A Review On : Sustained Release Oral Drug Delivery System." International Journal in Pharmaceutical Sciences 1, no. 12 (2023): 771–83. https://doi.org/10.5281/zenodo.10401318.

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Oral drug delivery is the most preferred and convenient option as the oral route provides maximum active surface area among all drug delivery system for administration of various drugs. The attractiveness of these dosage forms is due to awareness to toxicity and ineffectiveness of drugs when administered by oral conventional method in the form of tablets &amp; capsules. Usually, conventional dosage form produces wide range of fluctuation in drug concentration in the bloodstream and tissues with consequent&nbsp; undesirable toxicity and poor efficiency. The maintenance of concentration of drug
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Vigneshwaran, LV, Abdullakunhi Thasneem, Irfana BM Fathimath, PV Thushara, Sebastin V., and Babu TK Ajith. "DERMAL DRUG DELIVERY THROUGH NANOCARRIERS." World Journal of Pharmaceutical Science and Research 2, no. 4 (2023): 25–28. https://doi.org/10.5281/zenodo.10897614.

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Nanocarriers have been explored for delivering drugs and other bioactive molecules for well over 35years. Since the introduction of a nanoliposomal delivery system for the cancer drug doxorubicin, several products have been approved worldwide. The majority of these products focus on cancer chemotherapy, and utilize the size advantage of nanocarriers to obtain a favourable distribution of the drug carrier in the human body. In general, such carriers do not sustain drug release over more than a few days at best. A variety of nanocarriers have been studied, and their advantages and shortcomings a
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Jyoti, Gupta Hans Raj* Divya. "Emerging Frontiers In Sustained Release Drug Delivery Systems: Unveiling The Latest Innovations And Future Perspectives." International Journal in Pharmaceutical Sciences 1, no. 2 (2023): 186–206. https://doi.org/10.5281/zenodo.8267084.

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Sustained release drug delivery systems have emerged as a promising approach to improve therapeutic effectiveness and patient compliance. This review article aims to provide a comprehensive overview of the advancements in sustained release drug delivery systems, focusing on design principles, formulation strategies, and novel approaches. The introduction highlights the background and significance of sustained release drug delivery systems in optimizing therapy for chronic conditions. The objectives of the review article include exploring the factors influencing system design, considering patie
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Dissertations / Theses on the topic "Sustained-release drug delivery"

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McMillan, Hannah Louise. "Sustained release biodegradable ocular drug delivery systems." Thesis, Queen's University Belfast, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.678216.

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Delivery of drugs to the posterior segment of the eye is notoriously difficult and unfortunately many chronic conditions of the posterior segment often lead to sight-loss if not treated effectively. Current methods of delivery such as topical drops result in poor bioavailability at the back of the eye, while the blood brain retina imposes restrictions on the entry on drugs into the eye delivered by the systemic system. The gold-standard method for delivery of therapeutic concentrations of drugs is intravitreal delivery, which involves an injection into the vitreous cavity. Although this provid
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Wilding, Ian Robert. "Some studies of oral sustained release of pellet systems." Thesis, University of Nottingham, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.319343.

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Rodriguez, Lidia Betsabe. "Controlled Release System for Localized and Sustained Drug Delivery Applications." University of Toledo / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1365107103.

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Zhang, Feng. "Hot-melt extrusion as a novel technology to prepare sustained-release dosage forms /." Digital version accessible at:, 1999. http://wwwlib.umi.com/cr/utexas/main.

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Awang, Mohamed Bin. "Radiolabelling of pharmaceutical dosage forms by neutron activation of Samarium-152." Thesis, University of Nottingham, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.261026.

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Hodsdon, Alison Claire. "Xanthan gum and sodium alginate as sustained-release carriers in hydrophilic matrix tablets." Thesis, University of Nottingham, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259859.

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Lee, K. V. "Optimisation and analysis of sustained release drug delivery systems to treat ocular disease." Thesis, University College London (University of London), 2013. http://discovery.ucl.ac.uk/1400532/.

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Transscleral drug delivery has been a moreviable alternative drug delivery route to the posterior segment than other more invasive methods. The drug absorption involves passing through several layers of tissue, including the sclera and retinal pigment epithelium (RPE), to reach the retina. Posterior scleral thickness in both humans and normal C57BL/6 mice decreases with age. Lipofuscin density in albino mice’s eyes were two-fold higher than in pigmented mice and the drug-binding to these pigments could affect drug bioavailability. Drug molecular weight didn’t correlate with penetration efficie
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Avgoustakis, Konstantine. "Synthesis and evaluation of some poly(lactide-co-glycolides) for use in sustained release tablets." Thesis, King's College London (University of London), 1992. https://kclpure.kcl.ac.uk/portal/en/theses/synthesis-and-evaluation-of-some-polylactidecoglycolides-for-use-in-sustained-release-tablets(8b664ccc-71de-4a1c-8995-7b7f9c72e905).html.

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Chopra, Poonam. "Ocular Iontophoresis of Nanocarriers for Sustained Drug Delivery to the Eye." University of Cincinnati / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1353951512.

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Manna, Soumyarwit. "Sustained Release Micro-implants for Delivery of Hydrophilic Drugs to Treat Vitreoretinal Diseases." University of Cincinnati / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1471346005.

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Books on the topic "Sustained-release drug delivery"

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Radomsky, Michael L., and Judy Senior. Sustained-Release Injectable Products. Taylor & Francis Group, 2019.

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Radomsky, Michael L., and Judy Senior. Sustained-Release Injectable Products. Taylor & Francis Group, 2000.

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Book chapters on the topic "Sustained-release drug delivery"

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Mantripragada, Sankaram B., and Stephen B. Howell. "Sustained-Release Drug Delivery with DepoFoam." In Drug Delivery Systems in Cancer Therapy. Humana Press, 2004. https://doi.org/10.1007/978-1-59259-427-6_12.

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Zheng, Xiao, Teng Guo, Fei Wu, Lan Shen, and Xiao Lin. "Sustained-Release Drug Delivery Systems of Chinese Medicines." In Novel Drug Delivery Systems for Chinese Medicines. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-3444-4_3.

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Macdonald, R. Loch. "Site-Specific, Sustained-Release Drug Delivery for Subarachnoid Hemorrhage." In Translational Stroke Research. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-9530-8_32.

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Sharma, Kartikey, and Vandana Guleria. "Adoption of Smart Materials for Sustained and Controlled Drug Release." In Smart Micro- and Nanomaterials for Drug Delivery. CRC Press, 2024. http://dx.doi.org/10.1201/9781003468424-16.

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Lee, Susan S., Michael R. Robinson, and Scott M. Whitcup. "Sustained-Release Ocular Drug Delivery Systems: Bench to Bedside Development." In Methods in Pharmacology and Toxicology. Humana Press, 2013. http://dx.doi.org/10.1007/7653_2013_3.

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Patel, Kavil, and Fang Liu. "Advanced Oral Sustained-Release Drug Delivery Systems for Older Patients." In Pharmaceutical Formulations for Older Patients. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-35811-1_6.

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Ponnusami, V. "Polyelectrolyte Complex-Based Ionically Gelled Biopolymeric Systems for Sustained Drug Release." In Ionically Gelled Biopolysaccharide Based Systems in Drug Delivery. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-2271-7_6.

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O’Rourke, Michael J., and Clive G. Wilson. "The Development and Commercialization of Sustained-Release Ocular Drug Delivery Technologies." In Ophthalmic Product Development. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-76367-1_21.

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Kumar, Amrish, Sunil K. Jain, Dinesh K. Mishra, and Rupesh Gautam. "Influence of Drug Properties and Routes of Drug Administration on Design of Sustained and Controlled Release Systems." In Novel Carrier Systems for Targeted and Controlled Drug Delivery. Springer Nature Singapore, 2024. https://doi.org/10.1007/978-981-97-4970-6_1.

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Zhang, Xue, Xiao Liu, Ze-Hui Wei, and Yan-Ping Huang. "Special Control by Molecularly Imprinted Materials-Zero-Order Sustained Release, Enantioselective MIPs, and Self-Regulated Drug Delivery Microdevices." In Molecularly Imprinted Polymers as Advanced Drug Delivery Systems. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-0227-6_3.

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Conference papers on the topic "Sustained-release drug delivery"

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Asadian, Mitra, Fariba Ganji, and Ladan Rashidi. "Sustained release drug delivery system based on MSNs dispersed in an injectable in-situ gelling chitosan hydrogel." In 2024 31st National and 9th International Iranian Conference on Biomedical Engineering (ICBME). IEEE, 2024. https://doi.org/10.1109/icbme64381.2024.10895086.

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TOMÁNKOVÁ, Hana, Miroslava RYSOVÁ, Marie SCHNEIDROVÁ, and Hana SKLENÁŘOVÁ. "SILICA DIOXIDE NANOFIBER BASED DRUG DELIVERY SYSTEM WITH SUSTAINED RELEASE." In NANOCON 2019. TANGER Ltd., 2020. http://dx.doi.org/10.37904/nanocon.2019.8770.

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Zhang, Xiao-Fei, Deng-Guang Yu, Li-Min Zhu, C. Branford-White, S. Dowden, and Xiang-Liang Yang. "Sustained-Release Floating Drug Delivery Systems Prepared Using Three-Dimensional Printing." In 2009 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE). IEEE, 2009. http://dx.doi.org/10.1109/icbbe.2009.5163546.

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Pritchard, Eleanor M., Andrew Wilz, Tianfu Li, Jing-Quan Lan, Detlev Boison, and David L. Kaplan. "Sustained-release silk biomaterials for drug delivery and tissue engineering scaffolds." In 2009 IEEE 35th Annual Northeast Bioengineering Conference. IEEE, 2009. http://dx.doi.org/10.1109/nebc.2009.4967659.

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Starly, Binil, Shih-Feng Lan, and David Schmidtke. "Customized Release of Metronidazole From Composite Casted Rings of Poly-Caprolactone/Alginate for Periodontal Drug Delivery." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14177.

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Dental implants provide support for dental crowns and bridges by serving as abutments for the replacement of missing teeth. The objective of this study was to demonstrate a novel method of controlled localized delivery of antibacterial agents to an implant site using a custom fabricated ring. The study involved incorporating a model antibacterial agent (metronidazole) into custom designed Poly-ε-Caprolactone/Alginate (PCL/Alginate) composite rings to produce the intended controlled release profile. In vitro release studies indicate that pure (100%) alginate rings exhibited an expected burst re
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Blanco, E., T. Sangai, A. Hsiao, et al. "Abstract P6-11-11: Multistage Delivery of Paclitaxel: Increased Drug Stability and Sustained Release Results in Enhanced Efficacy in Breast Cancer." In Abstracts: Thirty-Fifth Annual CTRC‐AACR San Antonio Breast Cancer Symposium‐‐ Dec 4‐8, 2012; San Antonio, TX. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/0008-5472.sabcs12-p6-11-11.

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Vakati, Snehal Reddy, Matthew Gacura, Gary Vanderlaan, et al. "Synthesis of Poly-Lactic Acid by Ring Open Polymerization for Biomedical Applications." In ASME 2023 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2023. http://dx.doi.org/10.1115/imece2023-113972.

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Abstract Poly-lactic acid (PLA) is a synthetic polymer that has gained popularity as a scaffold due to well-established manufacturing processes, predictable biomaterial properties, and sustained therapeutic release rates. However, it has some drawbacks such as weak mechanical parameters and reduced medicinal delivery efficacy after PLA degradation. The development of synthetic polymers that can release antibiotics and other medicines remains a top research priority. This study proposes a novel approach to produce PLA by converting Brewer’s spent grain (BSG) into lactic acid by bacterial fermen
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Sandri, Monica, Michele Iafisco, Silvia Panseri, Elisa Savini, and Anna Tampieri. "Fully Biodegradable Magnetic Micro-Nanoparticles: A New Platform for Tissue Regeneration and Theranostic." In ASME 2013 2nd Global Congress on NanoEngineering for Medicine and Biology. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/nemb2013-93223.

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Nowadays, magnetic materials are receiving special attention due to their potential applications in different fields and in particular in medicine. Magnetic micro-nano-particles have been progressively employed as support materials for enzyme immobilization, and have been used as drug-delivery vehicles, contrast agents for magnetic resonance imaging as well as heat mediators for hyperthermia-based anti-cancer treatments and many other exciting biomedical applications. Magnetic materials have also attracted a big interest in the field of bone tissue regeneration because it has been demonstrated
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