Log in

Relevant bibliographies by topics / Sustained Release Formulations / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Sustained Release Formulations.

Dissertations / Theses on the topic 'Sustained Release Formulations'

Author: Grafiati

Published: 4 June 2025

Last updated: 14 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 46 dissertations / theses for your research on the topic 'Sustained Release Formulations.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Purkiss, Ronald. "Bioequivalence of sustained release theophylline formulations." Thesis, Aston University, 1986. http://publications.aston.ac.uk/12472/.

Full text

Abstract:

The bioequivalence of sustained release theophylline formulations, marketed in the United Kingdom, has been investigated in relation to the co-administration of food in both single dose and steady state volunteer studies. The effect of food on pharmacokinetic parameters and their clinical relevance was researched. Experimentation using drug induced modification of gastric motility to ascertain the component influences of the rate of gastric emptying on the absorption of theophylline from sustained release formulations was conducted. Prolongation of time to maximum plasma theophylline concentra

APA, Harvard, Vancouver, ISO, and other styles

2

Lee, Jobina J. N. "Investigations into sustained-release hydrophobic matrix pellet formulations." Thesis, University of Strathclyde, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275167.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Wagner, Daniel. "Sustained release formulations for compounds underlying intestinal drug efflux." [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=96927890X.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Sachikonye, Tinotenda Chipo Victoria. "Development and assessment of minocycline sustained release capsule formulations." Thesis, Rhodes University, 2010. http://hdl.handle.net/10962/d1013127.

Full text

Abstract:

The use of minocycline for the treatment of a broad range of systemic infections and for severe acne has been associated with vestibular side effects. The severity of side effects may lead to poor adherence to therapy by patients. The use of sustained release formulations of minocycline that display slow dissolution of minocycline following administration may be beneficial in reducing the incidence and severity of side effects. Therefore, sustained release capsule dosage forms containing 100 mg minocycline (base) were manufactured and assessed for use as sustained release oral dosage forms of

APA, Harvard, Vancouver, ISO, and other styles

5

Janoria, Kumar Gaurav Mitra Ashim K. "Transporter targeted prodrug approach and sustained release formulations for ocular delivery of ganciclovir." Diss., UMK access, 2008.

Find full text

Abstract:

Thesis (Ph. D.)--School of Pharmacy and Dept. of Chemistry. University of Missouri--Kansas City, 2008.<br>"A dissertation in pharmaceutical sciences and chemistry." Advisor: Ashim K. Mitra. Typescript. Vita. Description based on contents viewed Sept. 12, 2008; title from "catalog record" of the print edition. Includes bibliographical references (leaves 193-204). Online version of the print edition.

APA, Harvard, Vancouver, ISO, and other styles

6

Hildebrandt, Christian. "Crystalline Monoclonal Antibodies: Development of stable crystals for drying and sustained release formulations." Diss., Ludwig-Maximilians-Universität München, 2014. http://nbn-resolving.de/urn:nbn:de:bvb:19-174392.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Marquette, Sarah. "Stabilization and development of sustained-release formulations of protein/antibody for subcutaneous delivery." Doctoral thesis, Universite Libre de Bruxelles, 2014. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209251.

Full text

Abstract:

ABSTRACT<p><p>This project aimed at developing a drug delivery system (DDS) able to enhance the stability and<p>residence time in vivo of antibodies (Abs). The system will deliver drug by the subcutaneous<p>route (SC), while ensuring accurate control of the drug release and the resulting plasmatic level. This technology platform will allow to reduce frequency of injection, potentially decrease side effects and maintain high concentration of Abs which will improve life of patient having chronic disease such as autoimmune and inflammatory disease. Biodegradable synthetic polymer-based formulatio

APA, Harvard, Vancouver, ISO, and other styles

8

Ruberg, Eva-Maria. "Development of sustained release formulations for the intra-articular delivery of a therapeutic antibody." Diss., Ludwig-Maximilians-Universität München, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-183255.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Hildebrandt, Christian [Verfasser], and Gerhard [Akademischer Betreuer] Winter. "Crystalline Monoclonal Antibodies: Development of stable crystals for drying and sustained release formulations / Christian Hildebrandt. Betreuer: Gerhard Winter." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2014. http://d-nb.info/1059351412/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Nieto, Bobadilla Maria Susana. "A new antibacterial agent : in vitro bacteriological characterization and in vitro/in vivo performance of sustained release formulations." Thesis, Lille 2, 2015. http://www.theses.fr/2015LIL2S018/document.

Full text

Abstract:

Introduction : La résistance aux antibiotiques est une menace de santé, il est donc urgent de développer de nouveaux antibactériens. CIN-102, est un nouvel antibactérien développé par une industrie pharmaceutique. Il possède un large-spectre d’action et aucune résistance n’a été développée jusqu’à présent. Parmi les possibles applications thérapeutiques du CIN-102, notre recherche s’est focalisée sur les Maladies Inflammatoires Chroniques de l’Intestin (MICIs). Plusieurs facteurs contribuent à l’étiologie des MICIs. Les bactéries intestinales jouent un rôle important dans ces maladies et une a

APA, Harvard, Vancouver, ISO, and other styles

11

Ruberg, Eva-Maria [Verfasser], and Wolfgang [Akademischer Betreuer] Frieß. "Development of sustained release formulations for the intra-articular delivery of a therapeutic antibody / Eva-Maria Ruberg. Betreuer: Wolfgang Frieß." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2013. http://d-nb.info/1072376660/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Parent, Marianne. "Formulations in situ de donneurs de monoxyde d'azote." Thesis, Université de Lorraine, 2013. http://www.theses.fr/2013LORR0127/document.

Full text

Abstract:

Les systèmes in situ sont des liquides à base de polymère et de solvant organique pharmaceutiquement acceptable, contenant le principe actif. Après injection sous-cutanée, lors du contact avec les fluides corporels, le polymère précipite sous forme d'implant (ISI) ou de microparticules (ISM) qui se dégradent progressivement en libérant le principe actif. Dans ce travail, des ISI et des ISM réalisés à partir d'un copolymère d'acide lactique et glycolique ont été développés pour la libération prolongée de S-nitrosothiols (RSNO), des donneurs de monoxyde d'azote. L'influence du type de formulatio

APA, Harvard, Vancouver, ISO, and other styles

13

Nastiti, Christofori Maria Ratna Rini. "Development and evaluation of polymeric nanoparticle formulations for triamcinolone acetonide delivery." Thesis, Curtin University, 2007. http://hdl.handle.net/20.500.11937/613.

Full text

Abstract:

The aims of this study were to develop polymeric NP formulations for triamcinolone acetonide (TA) delivery, from biodegradable and biocompatible hydrophobic polymers, which provide sustained release, prolonged stability and low toxicity, and to assess the toxicity of TA NPs (TA-NPs) compared to TA alone upon BALB/c 3T3 and ARPE 19 cell culture models.The study involved investigation of three different types of polymers: poly(D,L,lactide) (PDLLA), poly(D,L,lactide-co-glycolide)(PLGA) and methoxypolyethyleneglycol poly(D,L,lactide-co-glycolide)(mPEG PLGA). Two different methods were studied in t

APA, Harvard, Vancouver, ISO, and other styles

14

Hadba, Ahmad Robert. "Synthesis, properties, and in vivo evaluation of sustained release albumin-mitoxantrone microsphere formulations for nonsystemic treatment of breast cancer and other high mortality cancers." [Gainesville, Fla.] : University of Florida, 2001. http://etd.fcla.edu/etd/uf/2001/anp1596/master.PDF.

Full text

Abstract:

Thesis (Ph. D.)--University of Florida, 2001.<br>Title from first page of PDF file. Document formatted into pages; contains xxii, 198 p.; also contains graphics. Vita. Includes bibliographical references (p. 179-196).

APA, Harvard, Vancouver, ISO, and other styles

15

Khamanga, Sandile Maswazi Malungelo. "Formulation and assessment of verapamil sustained release tablets." Thesis, Rhodes University, 2005. http://hdl.handle.net/10962/d1018236.

Full text

Abstract:

The oral route of drug administration is most extensively used due to the obvious ease of administration. Verapamil hydrochloride is a WHO listed phenylalkylarnine, L-type calcium channel antagonist that is mainly indicated for cardiovascular disorders such as angina pectoris, supraventricular tachycardia and hypertension. Due to its relatively short half-life of approximately 4.0 hours, the formulation of a sustained-release dosage form is useful to improve patient compliance and to achieve predictable and optimized therapeutic plasma concentrations. Direct compression and wet granulation wer

APA, Harvard, Vancouver, ISO, and other styles

16

Treki, Mahmud Sighayer. "Formulation and evaluation of propylene glycol monostearate microspheres for sustained release of nitrofurantoin." Scholarly Commons, 1988. https://scholarlycommons.pacific.edu/uop_etds/3366.

Full text

Abstract:

Sustained release of nitrofurantoin (NFT) from microspheres of propylene glycol monostearate (PGM) and of PGM and ethoxylated stearyl alcohol (ESA) prepared by the meltable dispersion and cooling process was investigated. The microspheres (30-850 mu) were nonsticky, discrete and free flowing. Both the rate and extent of in vitro release of NFT (from NFT-PGM microspheres in distilled water at 37 degrees C under constant agitation at 50 rpm) declined with decreasing NFT/PGM ratio. The effect of incorporating ESA over the range of 0.01 to 0.05% w/w of PGM in formulations with NFT/PGM ratios of 1:

APA, Harvard, Vancouver, ISO, and other styles

17

Tian, Weiwei. "The Development of Sustained Release Formulation for Pharmaceutical Proteins based on Vesicular Phospholipid Gels." Diss., lmu, 2010. http://nbn-resolving.de/urn:nbn:de:bvb:19-117275.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Kieser, Leith Faye. "Formulation and assessment of monolithic beta blocker sustained release tablets prepared by direct compression." Thesis, Rhodes University, 2002. http://hdl.handle.net/10962/d1003242.

Full text

Abstract:

Beta blockers are commonly prescribed for the chronic treatment of hypertension, one of the most prolific disease states worldwide. The beta blockers selected for this study include acebutolol hydrochloride, labetalol hydrochloride, metoprolol tartrate oxprenolol hydrochloride and propranolol hydrochloride. All of these compounds have a short elimination half-life, necessitating multiple dose per day regimens and therefore the development of sustained release dosage forms incorporating these agents was considered beneficial in terms of extending the dosing interval, with the aim of improving p

APA, Harvard, Vancouver, ISO, and other styles

19

Duvvuri, Sridhar Mitra Ashim K. "Development and characterization of poly (D, L-lactide-co-glycolide) based sustained release formulation of ganciclovir in treatment of cytomegalovirus retinitis." Diss., UMK access, 2005.

Find full text

Abstract:

Thesis (Ph. D.)--School of Pharmacy and Dept. of Chemistry. University of Missouri--Kansas City, 2005.<br>"A dissertation in pharmaceutical science and chemistry." Advisor: Ashim K. Mitra. Typescript. Vita. Description based on contents viewed Mar. 12, 2007; title from "catalog record" of the print edition. Includes bibliographical references (leaves 138-147). Online version of the print edition.

APA, Harvard, Vancouver, ISO, and other styles

20

Seidenberger, Tanja Verfasser], Karsten [Akademischer Betreuer] [Mäder, Jürgen Akademischer Betreuer] Siepmann, and Reinhard H. H. [Akademischer Betreuer] [Neubert. "Sucrose ester stearates, amphiphilic matrix systems for the formulation of sustained release preparations / Tanja Seidenberger. Betreuer: Karsten Mäder ; Jürgen Siepmann ; Reinhard Neubert." Halle, Saale : Universitäts- und Landesbibliothek Sachsen-Anhalt, 2011. http://d-nb.info/1025136012/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Al, Yaman Khaled. "Nouvelle génération de bolaamphiphiles pour la libération prolongée de principes actifs : conception, synthèse et validation de preuve de concept." Electronic Thesis or Diss., Bordeaux, 2025. http://www.theses.fr/2025BORD0057.

Full text

Abstract:

L'efficacité des liposomes en tant que nanovecteurs est grandement compromise par leurs problèmes de stabilité. L'objectif de ce travail est de développer des liposomes à libération prolongée de nouvelle génération pour une diffusion passive des principes actif. L'utilisation de bolaamphiphiles en tant qu'éléments de formulation peut offrir des perspectives intéressantes pour la conception de liposomes stables: les bolasomes. Cependant, l'une des principales limitations des molécules de type bola est leur propension à former des membranes planes non adaptées à la délivrance de principes actifs

APA, Harvard, Vancouver, ISO, and other styles

22

Chaibva, Faith Anesu. "The use of response surface methodology and artificial neural networks for the establishment of a design space for a sustained release salbutamol sulphate formulation." Thesis, Rhodes University, 2010. http://hdl.handle.net/10962/d1010432.

Full text

Abstract:

Quality by Design (QbD) is a systematic approach that has been recommended as suitable for the development of quality pharmaceutical products. The QbD approach commences with the definition of a quality target drug profile and predetermined objectives that are then used to direct the formulation development process with an emphasis on understanding the pharmaceutical science and manufacturing principles that apply to a product. The design space is directly linked to the use of QbD for formulation development and is a multidimensional combination and interaction of input variables and process p

APA, Harvard, Vancouver, ISO, and other styles

23

Gallon, Gilmary. "Développement de microparticules hybrides à base d'huiles végétales réticulées par voie sol-gel pour la libération de molécules thérapeutiques." Thesis, Montpellier, 2017. http://www.theses.fr/2017MONTT184/document.

Full text

Abstract:

La formulation de médicaments regroupe des technologies innovantes où l'usage de matières premières naturelles émerge du fait de contraintes environnementales grandissantes. Les huiles végétales par exemple sont plébiscitées grâce à leurs propriétés remarquables en terme de solubilisation de principes actifs, de biocompatibilité et de biodégradabilité. Afin d'élargir leurs applications, notamment pour la libération prolongée de principes actifs, la solidification de ces huiles par réticulation a été envisagée à l'aide d'une chimie douce, c'est-à-dire respectueuse des principes de la chimie ver

APA, Harvard, Vancouver, ISO, and other styles

24

Polexe, Ramona Cristina. "Développement et caractérisation de nouveaux systèmes hybrides inorganique/organique pour la formulation de principes actifs." Thesis, Montpellier 2, 2010. http://www.theses.fr/2010MON20144/document.

Full text

Abstract:

Le sujet de cette thèse consiste à formuler et caractériser de nouveaux matériaux hybrides inorganique/organique pour la formulation et la libération de principes actifs. Ces matériaux sont constitués soit par des hydroxydes doubles lamellaires (HDL) et des phospholipides (PL) soit par des hydroxydes doubles lamellaires et du chitosane. Les matériaux hybrides hydroxydes doubles lamellaires/phospholipides ont été obtenus par échange anionique entre les anions du feuillet d'HDL et les phospholipides chargés négativement sous forme de liposomes. Les techniques d'analyse utilisées (DRX, ATG, UV et

APA, Harvard, Vancouver, ISO, and other styles

25

Gallon, Gilmary. "Développement de microparticules hybrides à base d'huiles végétales réticulées par voie sol-gel pour la libération de molécules thérapeutiques." Electronic Thesis or Diss., Montpellier, 2017. http://www.theses.fr/2017MONTT184.

Full text

Abstract:

La formulation de médicaments regroupe des technologies innovantes où l'usage de matières premières naturelles émerge du fait de contraintes environnementales grandissantes. Les huiles végétales par exemple sont plébiscitées grâce à leurs propriétés remarquables en terme de solubilisation de principes actifs, de biocompatibilité et de biodégradabilité. Afin d'élargir leurs applications, notamment pour la libération prolongée de principes actifs, la solidification de ces huiles par réticulation a été envisagée à l'aide d'une chimie douce, c'est-à-dire respectueuse des principes de la chimie ver

APA, Harvard, Vancouver, ISO, and other styles

26

Haji, mansor Muhammad. "Functionalized polymer implants for the trapping of glioblastoma cells Development of a non-toxic and non-denaturing formulation process for encapsulation of SDF-1α into PLGA/PEG-PLGA nanoparticles to achieve sustained release Reversing the Tumor Target: Establishment of a Tumor Trap". Thesis, Angers, 2019. http://www.theses.fr/2019ANGE0015.

Full text

Abstract:

Le glioblastome (GBM) est la forme de cancer du cerveau la plus courante et la plus meurtrière. Sa nature diffusive entraine une impossibilité d’élimination complète par chirurgie. Une récidive de la tumeur chez ≥ 90% des patients peut être provoqué par des cellules GBM résiduelles se trouvant près du bord de la cavité de résection. Un implant pouvant libérer de manière durable la protéine SDF-1α, qui se lie aux récepteur CXCR4 à la surface des cellules GBM, peut être utile pour induire le recrutement des cellules GBM résiduelles, permettre leur élimination sélective et finalement réduire la r

APA, Harvard, Vancouver, ISO, and other styles

27

Najberg, Mathie. "Development, physico-chemical characterization and biological evaluation of silk fibroin/hyaluronic acid freeze-dried sponges for the trapping of Glioblastoma cells Reversing the tumor target: Establishment of a tumor trap Development of a non-toxic and non-denaturing formulation process for encapsulation of SDF-1α into PLGA/PEG-PLGA nanoparticles to achieve sustained release". Thesis, Angers, 2019. http://www.theses.fr/2019ANGE0040.

Full text

Abstract:

Le glioblastome (GBM) est une tumeur dévastatrice du système nerveux central. Malgré un traitement agressif, les récidives sont inévitables et l'application d'une stratégie thérapeutique efficace demeure un défi. Le concept révolutionnaire de piège à cellules cancéreuses peut offrir de nouvelles opportunités. L'objectif est d'attirer et de confiner les cellules cancéreuses résiduelles entourant la cavité chirurgicale dans un implant polymère biomimétique délivrant des molécules chimio attractantes. Le SDF-1α, également appelé CXCL12, se lie sélectivement au récepteur CXCR4 à la surface des cel

APA, Harvard, Vancouver, ISO, and other styles

28

Rodrigues, Christelle. "Optimisation des posologies des antiépileptiques chez l’enfant à partir de données pharmacocinétiques pédiatriques et adultes Population pharmacokinetics of oxcarbazepine and its monohydroxy derivative in epileptic children A population pharmacokinetic model taking into account protein binding for the sustained-release granule formulation of valproic acid in children with epilepsy Conditional non-parametric bootstrap for non-linear mixed effect models Pharmacokinetics evaluation of vigabatrin dose for the treatment of refractory focal seizures in children using adult and pediatric data Pharmacokinetic extrapolation from adult to children in case of nonlinear elimination: a case study." Thesis, Sorbonne Paris Cité, 2018. https://wo.app.u-paris.fr/cgi-bin/WebObjects/TheseWeb.woa/wa/show?t=2398&f=17336.

Full text

Abstract:

Les enfants diffèrent des adultes non seulement en termes de dimension corporelle mais aussi en termes physiologiques. En effet, les phénomènes de développement et maturation interviennent au cours de la croissance. Ces processus ne sont pas linéaires et induisent des différences pharmacocinétiques et pharmacodynamiques. Ainsi, contrairement à la pratique commune, il n’est pas approprié de déterminer les posologies pédiatriques directement à partir des doses adultes. Étudier la pharmacocinétique chez l’enfant est fondamental pour pouvoir déterminer les posologies à administrer. La méthodologie

APA, Harvard, Vancouver, ISO, and other styles

29

Chen, Shan-Chiung, and 陳善炯. "Formulation Studies on Sustained Release Formulations for Diclofenac Sodium Tablets." Thesis, 1997. http://ndltd.ncl.edu.tw/handle/35875166440199717136.

Full text

Abstract:

博士<br>國立臺灣大學<br>藥學系<br>85<br>Diclofenac sodium was used as the model drug in this formulation study that hydrophilic matrices were proposed for the sustained-release of the drug. HPC-M, HPC-H, HPMC 2910, and/or HPMC 2208 in different proportions were compared for the matrix material to regulate the sustained release. The matrix type tablets were prepared by adding lactose or wax as the additives and then compressed. The resulting tablets with different f

APA, Harvard, Vancouver, ISO, and other styles

30

Wagner, Daniel [Verfasser]. "Sustained release formulations for compounds underlying intestinal drug efflux / Daniel Wagner." 2003. http://d-nb.info/96927890X/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Kung, Chao-Feng, and 龔朝峰. "Bioequivalence study of diclofenac sodium sustained-release formulations: Staren SR and Voltaren SR." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/38976699843621860952.

Full text

Abstract:

碩士<br>國立成功大學<br>臨床藥學研究所<br>84<br>Purpose The objective of the study was to compare the bioavailability of diclofenac sodium for the sustained-released formulation developed in Taiwan (Staren SR 100mg capsule) to that for the innovator formulation produced by Ciba-Geigy Limited(Voltaren SR 100mg tablet). Method Twelve healthy volunteers (21-26 years old) were administered 100 mg each of the two preparations every 24 hours over seven days in a two-way crossover fashion. A standardized brea

APA, Harvard, Vancouver, ISO, and other styles

32

Chou, Joyce Tian-wei. "Product formulations and in vitro-in vivo evaluation of 1) topical insect repellent formualtions against mosquitoes; 2) oral sustained release formulations of cefaclor and pentoxifylline in adults." Thesis, 1995. http://hdl.handle.net/1957/34667.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Chaibva, F. A., M. Burton, and Roderick Walker. "Optimization of salbutamol sulfate dissolution from sustained release matrix formulations using an artificial neural network." 2010. http://hdl.handle.net/10962/d1006034.

Full text

Abstract:

An artificial neural network was used to optimize the release of salbutamol sulfate from hydrophilic matrix formulations. Model formulations to be used for training, testing and validating the neural network were manufactured with the aid of a central composite design with varying the levels of Methocel® K100M, xanthan gum, Carbopol® 974P and Surelease® as the input factors. In vitro dissolution time profiles at six different sampling times were used as target data in training the neural network for formulation optimization. A multi layer perceptron with one hidden layer was constructed using

APA, Harvard, Vancouver, ISO, and other styles

34

Fahmy, Sahar Abd El-Sattar. "Development of novel spray coated soft elastic gelatin capsule sustained release formulations of nifedipine, bioavailability and bioequivalence of verapamil HCL controlled release formulations, pharmacokinetics of terbinafine after single oral doses in raptors." Thesis, 2004. http://hdl.handle.net/1957/29795.

Full text

Abstract:

This dissertation describes the development of a new sustained release formulation of nifedipine. The new formulation was developed by coating commercially available immediate release soft elastic gelatin capsules using a spray coating technique with two different polymeric combinations. Dissolution studies were conducted and showed that controlled release of nifedipine was obtained by increasing the ratio of the water insoluble polymer in the coat and increasing the percent weight gain of the coating. Simulated plasma concentration versus time profiles after administration of 30 mg dose of se

APA, Harvard, Vancouver, ISO, and other styles

35

Rakkanka, Vipaporn. "A novel self-sealing chewable sustained release tablet of acetaminophen ; Development and evaluation of novel itraconazole oral formulations ; A novel zero order release matrix tablet." Thesis, 2003. http://hdl.handle.net/1957/30894.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Sorasuchart, Waranush. "(1) : Evaluation of polycarbophil coated liposomes and membrane permeation of free and liposomal drugs; (2) : in vitro-in vivo evaluation of nicardipine HCl sustained-release formulations." Thesis, 1998. http://hdl.handle.net/1957/33656.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Chang, Ming-Tsung, and 張銘聰. "The formulation study of sustained release Venlafaxine HCl." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/63535454938862223590.

Full text

Abstract:

碩士<br>嘉南藥理科技大學<br>生物科技系暨研究所<br>95<br>The depression is not only a problem and phenomenon but also a real disease. It brings a destructive injury to patients. Venlafaxine is the newest anti-depression medicine. In the pharmacology, it is a kind of SNRI (Serotonin/Norepinephrine Reuptake Inhibitor) medicine. Due to its curative effect of the depression and safety on the anxious, it is very popular to doctors of psychiatric units and patients in the market. This research studied the technology of making high water soluble Venlafaxine HCl into a sustained release capsule containing 75 mg Venlafaxi

APA, Harvard, Vancouver, ISO, and other styles

38

Lee, Pei-Ling, and 李珮玲. "Formulation study of T1-11 oral sustained release tablets." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/52874633216949528902.

Full text

Abstract:

碩士<br>臺北醫學大學<br>生醫材料暨工程研究所<br>98<br>Huntington''s disease is still an incurable inherited disorder, and currently only symptomatic treatments are available. T1-11, a potential active ingredient for the treatment of Huntington’s disearse, is originally extracted from a traditional Chinese that can now be mass produced by chemical synthesis. Since patients with Huntington''s disease might have difficulties control their movements, thinking, and emotion, frequent drug dosing is not very convenient to the patients. Once per day of drug dosing that can ensure 24 hours of drug release would be ver

APA, Harvard, Vancouver, ISO, and other styles

39

Weng, Ling-Lun, and 翁翎倫. "Formulation design of tamsulosin hydrochloride orally disintegrating sustained-release tablets." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/25599816557485335781.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Hsiu-ChingYu and 游秀靜. "Study on Sustained-Release Gel Formulation of Novel Angiogenesis Factor for Chronic Wound Healing." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/z23x3q.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Mok, Miranda Jane. "Development and characterization of a sustained release formulation of lidocaine using liposomes exhibiting a transmembrane pH gradient." Thesis, 1997. http://hdl.handle.net/2429/5778.

Full text

Abstract:

Longer acting local anaesthetics which will provide prolonged nerve blockade are required for adequate management of both acute and chronic pain. It has been suggested that liposomes represent a potentially useful vehicle for sustained drug release following local administration. Thus, the aim of this thesis was to develop and characterize liposomal lidocaine by employing a transmembrane pH gradient to efficiently encapsulate lidocaine into large unilamellar vesicles (LUVs). The rate and extent of lidocaine uptake into LUVs exhibiting a pH gradient were determined and compared to drug a

APA, Harvard, Vancouver, ISO, and other styles

42

Tian, Weiwei [Verfasser]. "The development of sustained release formulation for pharmaceutical proteins based on vesicular phospholipid gels / vorgelegt von Weiwei Tian." 2010. http://d-nb.info/1005073775/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

"Development of a sustained-release microsphere formulation for delicate therapeutic proteins using a novel aqueous-aqueous emulsion technology." 2008. http://library.cuhk.edu.hk/record=b5896772.

Full text

Abstract:

Zhang, Xinran.<br>Thesis submitted in: December 2007.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2008.<br>Includes bibliographical references (leaves 80-87).<br>Abstracts in English and Chinese.<br>TITLE PAGE --- p.i<br>ABSTRACT --- p.ii<br>中文摘要 --- p.v<br>ACKNOWLEDGEMENTS --- p.vii<br>TABLE OF CONTENTS --- p.viii<br>LIST OF FIGURES --- p.xi<br>LIST OF TABLES --- p.xiv<br>ABBREVIATIONS --- p.xv<br>Chapter CHAPTER 1. --- Introduction<br>Chapter 1.1. --- Rationale of the Study --- p.1<br>Chapter 1.2. --- Current technologies for formulating long-acting parenteral protein deli

APA, Harvard, Vancouver, ISO, and other styles

44

Fabian, June. "Preformulation and formulation study of dexchlorphenniramine maleate for use in the development of a new sustained release dosage form." Thesis, 1994. https://hdl.handle.net/10539/25978.

Full text

Abstract:

A Dissertation Submitted to the Faculty of Medicine, University of the Witwatersrand, Johannesburg, in Partial Fulfilment of the Requirements for the Degree of Master of Pharmacy Johannesburg, March 1994<br>Preformulation and formulation study of dexchlor- pheniramine maleate (DCPM) for it's inclusion into a gelforming sustained release dosage form was investigated. A modification of the USP apparatus 2 is proposed as an alternative to currently recommended USP dissolution apparatus for floating, gelforming drug delivery systems. In addition, the role of magnesium stearate and talc as dissolu

APA, Harvard, Vancouver, ISO, and other styles

45

Yuh-Tyng, Huang. "A sustained-release formulation study on the hygroscopic drug (pyridostigmine bromide) and the investigation of in vitro/in vivo correlation characteristics." 2007. http://www.cetd.com.tw/ec/thesisdetail.aspx?etdun=U0011-3001200714382300.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Huang, Yuh-Tyng, and 黃郁婷. "A sustained-release formulation study on the hygroscopic drug (pyridostigmine bromide) and the investigation of in vitro/in vivo correlation characteristics." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/68541359609978944362.

Full text

Abstract:

博士<br>高雄醫學大學<br>藥學研究所博士班<br>95<br>Pyridostigmine bromide (PB), a highly hygroscopic drug was selected as the model drug. The PB sustained-release (SR) dosage forms (SR tableted-pellets and SR pellets) that were developed by extrusion-spheronization, direct compression and fluid-bed methods using Taguchi experimental and 23 full factorial design. Preceding in vitro studies, Taguchi experimental design was used to optimize formulations and process parameters for the extrusion-spheronization process to prepare drug-containing core pellets. Moreover, 23 full factorial design was utilized to search

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!