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Stickley, Elizabeth. "One Eyed Suze." Digital Commons at Loyola Marymount University and Loyola Law School, 2018. http://www.kaltura.com/tiny/gxxur.
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One Eyed Suze is an animated, anthology series that follows One Eyed Suze, former leader of the Loco Litter, after she is betrayed and left for dead by her own. She's rescued by a dimwitted rancher named Elliot and they embark on a journey of revenge and redemption.
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Dammert, Juan Luis. "Supe: Arguedas’s unfinished novel." Pontificia Universidad Católica del Perú, 2012. http://repositorio.pucp.edu.pe/index/handle/123456789/79433.
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Tuvo varios nombres: «Harina Mundo», «Mar de Harina», «Jonás», «El pez grande», y fue un proyecto literario que emprendió José María Arguedas después de la publicación de Todas las Sangres (1964). Con él quiso novelar «la transformación del puerto de Supe», lugar donde había pasado los veranos entre 1943 y 1963 y que conocía muy bien. Como sabemos, Arguedas terminó convirtiendo ese proyecto inicial en El zorro de arriba y el zorro de abajo, una novela límite y relato ambientado en el puerto de Chimbote. Dos capítulos de esta novela sobre Supe fueron publicados en vida del escritor, «Mar de Harina» y «El Pelón». En este artículo recojo información que da luces sobre estos textos y sus personajes, ya que fueron tomados de la realidad. Me baso en fuentes orales, tanto de mi memoria personal y familiar como de las conversaciones tenidas con pobladores actuales del puerto en un conversatorio en 2004 sobre los personajes descritos en el inacabado proyecto novelístico.<br>It had several names, «Harina Mundo», «Mar de Harina», «Jonás», «El pez grande», and was a literary project that José María Arguedas started after the publication of Todas las Sangres (1964). The novel was intended to tell the story of ‘the transformations of Puerto Supe’, a fishing town he knew well, for he spent there the summer of 1943 and 1963. As we know, Arguedas later transformed this project into his last novel called El zorro de Arriba y el zorro de Abajo, which took place in the port of Chimbote.Two chapters of the unfinished novel about Supe were published while Arguedas was still alive: «Mar de Harina» and «El Pelón». In this article I present information about those chapters and the characters they portray, given that they were taken from real life. For this purpose, I draw on oral sources, such as my personal memories and the conversations I held in 2004 with the current inhabitants of Supe, about the characters of this unfinished project.
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Payet, Karine. "Cessions immobilières à Suse." Lyon 2, 2007. http://demeter.univ-lyon2.fr/sdx/theses/lyon2/2007/payet_k.
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Ville d’Iran occidental, située dans l’actuelle plaine du Khuzistan au pied des monts Zagros, Suse tout au long de son histoire a été soumise à la double influence de la Mésopotamie et de la confédération élamite. C’est dans ce contexte d’alternance que s’est développée une civilisation complexe et originale. La compréhension de celle-ci passe par l’examen des actes d’achat qui ont été découverts lors des fouilles dirigées par R. De Mecquenem, effectuées entre 1927 et 1928 dans le secteur dit de la «Ville royale». Le corpus se compose de 99 textes rédigés en akkadien, sur des tablettes d’argiles non cuites, dont une première publication a été réalisée par V. Scheil, assyriologue de la mission dès 1930. Cette étude s’organise autour de deux axes principaux. L’analyse juridique complète du formulaire permet tout d’abord de mettre en évidence son évolution ainsi que sa structuration progressive. La comparaison des schémas ainsi obtenus avec ceux des principaux sites mésopotamiens et de la ville élamite de Kabnak, a contribué à l’établissement de points de ressemblance et de dissemblance attestant de l’originalité du droit susien. A l’intérieur de cette analyse, une attention particulière a été portée aux clauses faisant intervenir des notions élamites, de manière à essayer d’en donner l’interprétation la plus précise possible. Le second volet est consacré à la détermination des caractéristiques de la société susienne à partir des données contenues dans ces contrats. Pour établir un portrait de la ville aussi réaliste que possible, les indications fournies par les achats ont été comparées et complétées par la consultation de la totalité du corpus juridique, ainsi que par l’étude des données archéologiques et ethnologiques. Le croisement de ces diverses sources offre une image satisfaisante des cadres de la société susienne pendant la première moitié du deuxième millénaire<br>Susa is a city of western Iran located in the current plain of Khuzestan close to the Zagros mounts. Throughout its history, Susa was subjected to the double influence of Mesopotamia and Elamite Confederation. In such a dual context has grown a complex and original civilization. This survey is based on the acts of purchase which were discovered during excavations realised by R. De Mecquenem, between 1927 and 1928, in the so-called «Royal City» area. The corpus is made up of 99 texts written in akkadian on uncooked clay shelves, a first publication of which was accomplished by V. Scheil, assyriologist of mission from 1930. This study is organized around two main parts. In a first part, the complete legal analysis of the contracts made it possible to highlight their evolution like their progressive structuring. The results have been compared with those known for the main Mesopotamians sites like for the elamite city of Kabnak. This showed some points of resemblance and dissimilarity attesting of the originality of the Susan right. Within this analysis, a detailed attention was paid to the contracts utilizing elamite concepts, so as to try to give the most precise possible interpretation of it. In a second part, the data contained in these contracts are analysed in order to obtain the characteristics of the Susan society. To establish a realistic portrait of the city, the indications provided by the purchases were compared and supplemented by the consultation of the whole legal corpus, and by the study of the archaeological and ethnological data. The crossing of these various sources offers a complete image of the Susan society during first half of the second millennium
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Payet, Karine Malbran-Labat Florence. "Cessions immobilières à Suse." [S. l.] : [s. n.], 2007. http://demeter.univ-lyon2.fr/sdx/theses/lyon2/2007/payet_k.
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Biasco, Giulia <1994>. "Qiu Jin: dalle sue poesie alle sue idee." Master's Degree Thesis, Università Ca' Foscari Venezia, 2020. http://hdl.handle.net/10579/16622.
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Questa tesi è dedicata alla figura di Qiu Jin (1875-1907), poetessa, rivoluzionaria e martire delle lotte che anticiparono la rivoluzione del 1911, nonché una delle prime femministe nazionaliste cinesi. Oltre a una descrizione della sua vita e delle sue attività, la presente tesi contiene una selezione delle sue poesie in lingua originale seguite da una traduzione in lingua inglese, suddivise in tre diverse fasi della sua vita (gli anni prima del matrimonio, la vita coniugale, la separazione e la vita pubblica) e corredate da un commento. Inoltre, vi è una selezione di alcuni passi tratti dal suo tanci Jingweishi, anch’essi corredati da un commento.
La scrittura per Qiu Jin, non rappresentava soltanto un modo per esprimere sé stessa, ma anche un modo per stabilire il suo ruolo nella storia.
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Chirivì, Giulia [Verfasser], Sherry [Akademischer Betreuer] Suyu, Eiichiro [Gutachter] Komatsu, and Sherry [Gutachter] Suyu. "Gravitational Lensing in 3D / Giulia Chirivì ; Gutachter: Eiichiro Komatsu, Sherry Suyu ; Betreuer: Sherry Suyu." München : Universitätsbibliothek der TU München, 2020. http://d-nb.info/123006107X/34.
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Jonsson, Fredrik. "Almost Sure Central Limit Theory." Thesis, Uppsala University, Department of Mathematics, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-121066.
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Ramos, Peralta Sebastian Alonso. "Centro comunitario de Supe Puerto." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2021. http://hdl.handle.net/10757/657635.
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Caral fue una civilización que desde el Formativo Inicial se estuvo asentando en los márgenes del río Supe. Actualmente se encuentran descubiertos más de 20 sitios arqueológicos en todo el Valle. El descubrimiento fue hecho por la arqueóloga Ruth Shady en 1994, que a pesar de que ya era conocida la existencia de estos vestigios arquitectónicos no se habían realizado investigaciones hasta esa fecha y recién a partir de las invasiones es que se decide iniciar con el fin de detener las destrucciones (Shady, 2015).
En la actualidad no ha mejorado el interés de las personas por informarse, proteger y mantener los sitios arqueológicos. Evidencia de esto son las noticias que informan sobre intenciones de algunos grupos de personas de apropiarse de zonas arqueológicas y sus respectivas áreas de amortiguamiento.
Por ello es necesario plantear un espacio que permita al usuario recobrar su identidad y busquen poner en valor sus costumbres.
En la presente investigación se hará un análisis histórico de la tipología del proyecto, así como del lugar. También se tendrá un análisis crítico de proyectos referenciales. Luego, se abordará el tema del lugar más a fondo junto con el análisis del usuario. Finalmente, con la información de lo hablado anteriormente se plantea la programación arquitectónica que tendrá el proyecto.
En conclusión, esta investigación tiene como fin presentar el por qué la necesidad del proyecto, los usos y áreas propuestas y la aproximación arquitectónica final.<br>Caral was a civilization that since the Early Formative settled on the banks of the Supe River. Currently more than 20 archaeological sites were discovered throughout the Valley. The discovery was made by the archeologist Ruth Shady in 1994, that although it was already known the existence of these architectonic vestiges, no investigations had been carried out until that date and it was only after the invasions that it was decided to start with the purpose of stop the destructions (Shady, 2015).
As of now, the interest of people to inform themselves, protect and maintain the archaeological sites has not improved. Evidence of this is the news that informs about intentions of some groups of people to appropriate archaeological zones and their respective buffer areas.
For this reason, it is imperative to propose a project that allow the user to recover their identity and seek to value their customs.
In the present investigation a historical analysis of the typology of the project will be made, as well as of the place. There will also be a critical analysis of referential projects. Then, the topic of the place will be addressed more thoroughly along with the user’s analysis. Finally, the architectural programming of the project will be proposed.
In conclusion, this research aims to argue why the need of the project, the proposed uses and areas and the final architectural approach.<br>Tesis
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Gonchigdanzan, Khurelbaatar. "ALMOST SURE CENTRAL LIMIT THEOREMS." University of Cincinnati / OhioLINK, 2001. http://rave.ohiolink.edu/etdc/view?acc_num=ucin990028192.
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Almenara, Bezancon Twiggi Nicole. "Albergue turístico cultural Caral-Supe." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2015. http://hdl.handle.net/10757/600387.
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Martinez-Sève, Laurianne. "Les figurines hellénisantes de Suse : contribution à l'histoire culturelle de Suse aux époques hellénistique et parthe." Paris 1, 1997. http://www.theses.fr/1997PA010504.
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Cinq cent vingt-neuf figurines de terre cuite provenant du site iranien de Suse et datées des époques hellénistique et parthe sont étudiées dans le but de définir quel fut l'impact de la culture grecque dans une grande ville du proche orient hellénise et de déterminer les modes de contact entre populations grecque et orientale. Les caractéristiques techniques, iconographiques et stylistiques des terres cuites sont décrites et commentées dans un catalogue, conçu en fonction des derniers développements de la recherche en matière de coroplathie et qui prend en compte les procédés de reproduction de type industriel que permet le moulage des figurines. La thèse comprend aussi un volume de synthèse organise en trois parties. Les figurines sont d'abord replacées dans leur contexte archéologique de manière à en préciser la date et la fonction. Les travaux effectués par les missions archéologiques qui fouillèrent les niveaux récents de Suse n'ont pas toujours été publiés et c'est donc l'occasion d'en présenter une étude synthétique. La deuxième partie concerne les procédés de fabrication des figurines qui sont d'abord décrits. Une comparaison avec les méthodes de fabrication plus anciennes montre que les figurines ont été produites par des coroplathes orientaux. L'étude met aussi en évidence la circulation de moules ou de figurines entre plusieurs sites de la région. La troisième partie traite de l'iconographie et du style des figurines susiennes. Elle confirme d'abord l'origine orientale des coroplathes qui adoptèrent souvent une iconographie grecque mais qui la transposèrent dans un style oriental, montre l'originalité du répertoire susien par rapport à celui des autres sites de la région et met en évidence l'importance de la culture grecque à Suse<br>529 figurines of terracotta dated of the hellenistic and parthian periods, which are from the Iranian site of Susa, are studied. The aim is to determine the action of the greek civilization in a great city of the near east and to examine cultural contacts between greek and oriental populations. Technical, iconographical and stylistical characters of the terracottas are discribed and commented in a catalogue which takes the evolution of the research in consideration : the use of molds allows a mechanical and industrial production of terracottas. With the catalogue, another volume is divided in three parts. First, the figurines are replaced in their archaeological context for specifying their chronology and their function. The works of the archaeological expeditions which have explored the late levels of susa had even not been published. It was interesting to present their results. The second part is about the fabrication of the figurines. If we compare the technic with the ancient ones, we can determine that the coroplasts were oriental workers. It's also possible to prove the circulation of figurines or molds from on site of the near east to another. The iconography and style of the Susian figurines are examined in the third part. The oriental origin of the coroplasts is corroborate by the fact that the workers frequently adopted a greek iconography but worked in an oriental style. The originality of the Susa's repertory and the importance of the greek culture in Susa are also showed
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Aza, Bustios Gonzalo Enrique. "Museo Arqueológico del Valle de Supe." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2021. http://hdl.handle.net/10757/655842.
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El proyecto está ubicado en Supe Pueblo, en la zona de San Nicolás. El planteamiento es de una arquitectura que respeta el paisaje con una volumetría simple, que no plantea desaparecer en la topografía sino mostrarse, presentando materiales, recorridos y visuales que fortalezcan el enlace entre arquitectura y su entorno.
La ubicación responde a una zona en donde no existen obstrucciones visuales debido a construcciones aledañas, ya que se encuentra rodeado de zonas agrícolas y de dos cerros, La Cruz y el Chimucapac. Cabe resaltar que se utiliza una pequeña parcela como parte de la exposición.
El proyecto muestra una clara sectorización con respecto a las áreas complementarias ubicadas en el primer nivel del proyecto. Las áreas de servicio se plantean en la parte posterior al proyecto junto con la zona de investigación; y finalmente la zona de recorrido museográfico que se encuentra a partir del segundo nivel hacia arriba. El acceso se hace por una sola vía en doble sentido, la Av. San Nicolás, la cual te lleva hacia la carretera Panamericana y hacia Supe Pueblo. La edificación considera que todos los recorridos se realicen a través de rampas.
La idea del proyecto es que el usuario vaya descubriendo visuales hacia el entorno conforme vaya recorriendo su arquitectura. La edificación es claramente visible, sin embargo, se utilizan distintos niveles en la volumetría para no afectar de una manera invasiva el paisaje. Además, se consideran miradores a distintos niveles para exponer el entorno y comprender la importancia del valle para la civilización Caral.<br>The project is located in Supe Pueblo, in the San Nicolás area. The approach is of an architecture that respects the landscape with a simple volumetry, which doesn´t propose to disappear in the topography but to show itself, presenting materials, routes and visuals that strengthen the link between architecture and its environment.
The location responds to an area where there are no visual obstructions due to nearby buildings, since it is surrounded by agricultural areas and two hills, La Cruz and Chimucapac. It should be noted that a small plot is used as part of the exhibition.
The project shows a clear sectorization with respect to the complementary areas located in the first level of the project. The service areas are raised in the back part of the project together with the research area; and finally the museum tour area that is from the second level upwards. Access is by a single two-way street, Av. San Nicolás, which takes you to the Panamericana Highway and to Supe Pueblo. The building considers that all routes are carried out through ramps.
The idea of the project is for the user to discover visuals towards the environment as they go through its architecture. The building is clearly visible, however, different levels are used in the volumetry so as not to affect the landscape in an invasive way. In addition, viewpoints are considered at different levels to expose the environment and understand the importance of the valley for the Caral civilization.<br>Tesis
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Ljiljana, Popović. "Model osiguranja useva od rizika suše." Phd thesis, Univerzitet u Novom Sadu, Fakultet tehničkih nauka u Novom Sadu, 2018. https://www.cris.uns.ac.rs/record.jsf?recordId=105388&source=NDLTD&language=en.
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Predmet ovog istraživanja je suša i model osiguranja useva od rizika suše na teritoriji Vojvodine. Na osnovu detaljnog istraživanja vremenskih klimatoloških uslova na ispitivanom području, cilj ove disertacije je da se identifikuju meteorološki parametari i indikatori pogodni za indeksno osiguranje, potom da se identifikovani indeksi (padavine, SPI i SPEI indeksi suše) testiraju i odredi koji od njih najviše pogoduje osiguranju useva od rizika suše u Vojvodini.<br>The subject of this research is drought phenomena and crop insurance model for managing drought risk, on the territory of Vojvodina Province. After detailed research of weather and climate conditions of research area, themain purpose of this dissertation is to identify meteorological parameters and indicators suitable for index based insurance. Then,to test them (rainfall, SPI and SPEI drought indices) in order to determine index that is most suitable for crop insurance in Vojvodina.
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Bayrak, Mehmet Çağrı Keskin Sıddıka Nilay. "Zemin suyu özelliklerinin emme basıncı üzerindeki etkileri /." Isparta : SDÜ Fen Bilimleri Enstitüsü, 2008. http://tez.sdu.edu.tr/Tezler/TF01119.pdf.
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Brenneisen, Bustamante María del Carmen, Fernández Alex Delgado, Hernández Orlando Luritta, and Lachira Marina Otero. "Plan estratégico aplicado al Puerto de Supe." Master's thesis, Pontificia Universidad Católica del Perú, 2016. http://tesis.pucp.edu.pe/repositorio/handle/123456789/7422.
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xiv, 220 h. : il. ; 30 cm<br>El concepto de puertos se ha transformado, los puertos se han convertido en centros logísticos de transporte intermodal de primer orden, en donde se realizan diversas actividades de valor agregado y se consolidan como entes promotores y facilitadores del crecimiento
económico y bienestar de las naciones. La presente investigación está orientada a c umplir esta máxima. El Plan Estratégico Aplicado del Puerto de Supe elaborado a través del modelo secuencial del proceso estratégico propone resolver el problema del uso y desarrollo del puerto de manera sostenible, los autores han brindado una solución no contemplada antes en el Plan Nacional de Puertos: la Coopetitividad Portuaria a través de la creación e integración de la Franja Logística Portuaria del Callao, una propuesta de alcance nacional, que permitirá al Puerto de Supe y aquellos puertos integrantes de la franja a ser un hub de referencia en el Pacifico sur. La transformación del Puerto de Supe requiere de una visión estratégica y de una gestión moderna que consiga convertir al puerto en un eje de desarrollo y obtener beneficios para la comunidad vinculada a través de la concesión. Factores claves como la rentabilidad y la relación ciudad-puerto son esenciales en la propuesta, cuyo propósito es generar una intensa actividad portuaria y ser un eslabón importante dentro de la cadena de suministro portuaria de la región, utilizando de manera eficiente sus recursos y la tecnología. La concesión del puerto, la creación de la Franja Logística Portuaria del Callao y la especialización en el manejo de carga a granel y minerales son los pilares para lograr que el Puerto de Supe avance hacia una situación esperada competitiva y de gran atractivo para sus distintos actores<br>Today, the concept of ports has been transformed, ports have become the main logistics centers for intermodal transport, where is performed a very important commercial industry and promotes economic growth and welfare of nations. Port of Supe Strategic Plan prepared through the sequential model of the strategic process proposes to solve the problem of the use and development of the port in a sustainable manner, the authors have provided a solution not covered before in the National Plan of Ports: Port competitiveness and cooperation through the creation and integration of the logistics group from Port of Callao, a proposed national level, which will allow Port of Supe to be a reference hub in the south Pacific. The transformation of Port of Supe requires an strategic vision and modern management to get convert the port into a hub of development and obtain benefits linked through the grant community. Key factors such as profitability and city-port relationship are essential in the proposal, which aims to generate an intense port activity and be an important link in the supply chain of the port in the region, efficiently using its resources and technology. The grant of the port, the creation of the Logistics group from Port of Callao and expertise in handling bulk cargo and minerals are the building blocks to make the Port of Supe progress towards a competitive and highly attractive expected situation for the different players involved.<br>Tesis
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Kaila, Risto. "On almost sure elimination of generalized quantifiers." Helsinki : University of Helsinki, 2001. http://ethesis.helsinki.fi/julkaisut/mat/matem/vk/kaila/.
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Ahmed, Nacer Anis. "Composition sure d’API fondée sur des contrats." Electronic Thesis or Diss., Université de Lorraine, 2021. http://www.theses.fr/2021LORR0265.
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La virtualisation et la croissance exponentielle des offres Cloud ont transformé les capacités de calcul et de stockage informatique en commodités que l’on peut acquérir à la demande. Cette tendance a également atteint les services traditionnellement opérés pour permettre le déploiement et la mise en service d’applications de toutes sortes. Dans le cadre de ce travail, nous considérons les services middleware qui constituent les éléments de base d'une architecture logicielle. Evidemment, l’utilisation des services middleware implique de faire des choix qui doivent être guidés par des critères de qualité de déploiement des services et de coûts. À cet égard, nous sommes confrontés à deux défis principaux, à savoir la sélection des services cloud les mieux adaptés aux besoins spécifiques des architectes, et la composition qui consiste à évaluer et à sélectionner un ensemble de services atomiques répondant aux besoins applicatifs des architectes. Dans les deux cas, cette sélection doit assurer d'une part les besoins opérationnels de l'entreprise, tels que la capacité de stockage et la localisation des services, et d'autre part la qualité du déploiement des services ou des applications, comme la minimisation des coûts de déploiement tout en maintenant des performances élevées et une sécurité garantie. Cette thèse de doctorat contribue à la sélection et la composition des services cloud. En premier lieu, cette thèse propose une méthodologie pour identifier les éléments clés de comparaison et leurs relations pour la sélection des services cloud. Cette méthodologie est basée sur des données réelles disponibles auprès des fournisseurs de services, des benchmarks et des enquêtes menées auprès d'architectes en cloud. En deuxième lieu, cette thèse propose une méthodologie pour la sélection de service qui repose sur : (1) la résolution des difficultés liées à l'incapacité de déterminer comment les paramètres de configuration d'un service, appelés également Non-Functional Attributes (NFA), peuvent avoir un impact sur les exigences Non-fonctionnelles (NFR) telles que la performance, la disponibilité et la sécurité ; (2) la réalisation d’une enquête pour attribuer des poids significatifs aux NFA et aux NFR en fonction des besoins des architectes en matière d’applications ; (3) la normalisation des valeurs des NFA en fonction des types de données de ces derniers à l’aide de méthodes de normalisation adéquates ; (4) l’utilisation de la méthode d’aide à la décision Ordered Weighted Averaging Aggregation operator (OWA) pour la classification des services cloud en fonction des besoins des architectes et (5) la proposition d’un algorithme de sélection de services qui utilise les valeurs NFA normalisées et la méthode de prise décision OWA. En dernier lieu, cette thèse fournit une méthodologie pour guider les architectes dans la sélection des compositions de plans de services pour leurs architectures. Cette méthodologie repose sur: (1) les résultats de l'étude de sélection des services et sur l'analyse du processus de composition des services du point de vue des architectes; (2) un algorithme de composition de services qui permet de générer des solutions de compositions dans un délai raisonnable, tout en adaptant la sélection des plans de service en fonction des besoins des architectes, notamment en termes de coûts. Nous avons validé l'efficacité de notre méthodologie de sélection de services cloud en utilisant des configurations réelles de plans de services et les commentaires d'experts du domaine. Cette validation a été effectuée pour deux types de services : les services cloud de bases de données relationnelles et les services cloud de mise en file d'attente. Pour la composition de services cloud, nous l'avons validée et appliquée à la sélection de services cloud composés de deux types de services : services cloud de base de données relationnelles et services cloud de mise en file d'attente<br>Virtualisation and the exponential growth of cloud offerings have turned computing and storage capacity into commodities that can be purchased on demand. This trend has also reached the services traditionally operated to enable the deployment and commissioning of applications of all kinds. In this work, we consider middleware services that are the basic elements of a software architecture. Obviously, the use of middleware services implies making choices that must be guided by service deployment quality and cost criteria. In this respect, we are faced with two main challenges, namely the selection of the cloud services that best suit the specific needs of the architects, and the composition that consists in evaluating and selecting a set of atomic services that meet the application needs. In both cases, this selection must ensure both the operational needs of the enterprise, such as storage capacity and location of services, and the quality of the service or application deployment, such as minimising deployment costs while maintaining high performance and ensured security. This thesis work contributes to the selection and composition of cloud services. Firstly, this thesis proposes a methodology to identify key comparison elements and their relationships for the selection of cloud services. This methodology is based on real data available from service providers, benchmarks and surveys achieved with cloud architects. Secondly, this thesis proposes a methodology for service selection based on (1) resolving the difficulties associated with the inability to determine how the service's configuration parameters, also known as Non-Functional Attributes (NFA), can impact the Non-Functional Requirements (NFR) such as performance, availability and security; (2) conducting a survey to assign meaningful weights to NFA and NFR based on the architects' needs; (3) normalising the NFA values according to their data types using appropriate normalisation methods; (4) using the Ordered Weighted Averaging Aggregation operator (OWA), which is a decision support method to classify cloud services according to architects' needs; and (5) proposing a service selection algorithm that uses the normalised NFA values and the OWA decision making method. Thirdly, this thesis provides a methodology to guide architects in the selection of services plans compositions for their architectures. This methodology is based on: (1) the results of the services selection study and the analysis of the services composition process from the architects' point of view; (2) An algorithm for services composition that generates composition solutions in a reasonable time, while adapting the selection of service plans according to the architects' needs, especially in terms of cost. We validated the effectiveness of our cloud service selection methodology using actual services plans configurations and feedback from domain experts. This validation was performed for two types of services: relational database cloud services and queuing cloud services. For cloud services composition, we validated and applied it to the selection of cloud services composed of two types of services: relational database cloud services and queuing cloud services
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Seguirin, Mejdi. "Contribution à la comprèhension du mécanisme d'oxydation des suies par NO2 dans les conditions des échappements Diesel : influence de la présence d'un catalyseur à base de platine." Mulhouse, 2005. http://www.theses.fr/2005MULH0790.
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La combustion des suies par NO2 dans les conditions opératoires de la régénération continue du filtre à particules en absence et en présence d'un catalyseur a été étudiée en lit fixe traversé. L'oxydation du carbone par un mélange gazeux contenant NO2, O2 et H2O à des températures inférieures à 450°C se déroule selon deux réactions d'oxydation distinctes : une réaction directe C-NO2 et une réaction coopérative C-NO2-O2. Dans cette dernière, la présence de NO2 a comme rôle principal la déstabilisation des complexes -C(O) formés à partir de la chimisorption de l'oxygène. L'effet principal de la vapeur d'eau dans la réaction C-NO2 consiste en la formation intermédiaire d'acide nitrique et nitreux en très faible quantité. Ces intermédiaires exercent un effet catalytique sur l'oxydation du carbone par NO2 sans affecter de manière notoire la réaction coopérative. L'addition d'un catalyseur à base de platine engendre une augmentation de la vitesse d'oxydation du carbone lorsque l'oxygène est présent dans le mélange gazeux. L'effet du catalyseur est attribué à la dissociation de l'oxygène et à son transfert à la surface du carbone. Un autre effet du platine est la réoxydation de NO en NO2 nécessaire pour la déstabilisation des complexes -C(O)<br>The combustion of soot by NO2 under the operation conditions of the continuous regeneration trap in absence and in presence of a catalyst was studied in fixed bed reactor. The oxidation of carbon by a gas mixture contaiming NO2, O2 and H2O at temperature lower than 450°C proceeds according to two distinct oxidation reactions : a direct reaction C-NO2 and a co-operative reaction C-NO2-O2. In the latter, NO2 promotes the decomposition of the intermediate C(O) complex formed from the chimisorption of oxygen. The principal effect of the water vapour in the C-NO2 reaction is attributed to the intermediate formation of traces of nitric and nitrous acids. These intermediate species exert a catalytic effect on the oxidation of carbon by N02 without having a measurable effect on the co-operative reaction. The addition of a Pt-based catalyst leads to an increase in the rate of carbon oxidation when oxygen is present in the gas mixture. The effect of catalyst is attributed to the dissociation of oxygen and its transfer to the carbon surface. Another effect of platinum is the reoxidation of NO in NO2 necessary for the destabilisation of the -C(O) complexes
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Chao, Chun-Yi [Verfasser], Sherry [Akademischer Betreuer] Suyu, Eiichiro [Gutachter] Komatsu, and Sherry [Gutachter] Suyu. "Finding Lensed Quasars with Time Variability in Imaging Surveys / Chun-Yi Chao ; Gutachter: Eiichiro Komatsu, Sherry Suyu ; Betreuer: Sherry Suyu." München : Universitätsbibliothek der TU München, 2020. http://d-nb.info/1217406026/34.
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Zeebari, Zangin. "On Median and Ridge Estimation of SURE Models." Doctoral thesis, Internationella Handelshögskolan, Högskolan i Jönköping, IHH, Economics, Finance and Statistics, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-19681.
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This doctoral dissertation is a progressive generalization of some of the robust estimation methods in order to make those methods applicable to the estimation of the Seemingly Unrelated Regression Equations (SURE) models. The robust methods are each of the Least Absolute Deviations (LAD) estimation method, also known as the median regression, and the ridge estimation method. The first part of the dissertation consists of a brief explanation of the LAD and the ridge methods. The contribution of this investigation to the statistical methodology is focused on in the second part of the dissertation, which consists of 5 articles. The first article is a generalization of the median regression to the estimation of the SURE models. The proposed methodology is compared with each of the Generalized Least Squares (GLS) method and the median regression of individual regression equations. The second article generalizes the median regression on the conventional multivariate regression analysis, i.e., the SURE models with the same design matrices of the equations. The results are compared with the median regression of individual regression equations and the conventionally used OLS estimation method for such models (which is equivalent to the GLS estimation, as well). In the third article, the author develops ridge estimation for the median regression. Some properties and the asymptotic distribution of the estimator presented are investigated, as well. An empirical example is used to assess the performance of the new methodology. In the fourth article, the properties of some biasing parameters used in the literature for ridge regression are investigated when they are used for the new methodology proposed in the third article. In the last article, the methodologies of the four preceding articles are assembled in a more generalized methodology to develop the ridge-type estimation of the LAD method for the SURE models. This article has also provided an opportunity to investigate the behavior of some biasing parameters for the SURE models, which were previously used by some researchers in a non-SURE context.
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Landon, Nicolas. "Almost sure optimal stopping times : theory and applications." Phd thesis, Ecole Polytechnique X, 2013. http://pastel.archives-ouvertes.fr/pastel-00788067.
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Résumé : Cette thèse comporte 8 chapitres. Le chapitre 1 est une introduction aux problématiques rencontrées sur les marchés énergétiques : fréquence d'intervention faible, coûts de transaction élevés, évaluation des options spread. Le chapitre 2 étudie la convergence de l'erreur de couverture d'une option call dans le modèle de Bachelier, pour des coûts de transaction proportionnels (modèle de Leland-Lott) et lorsque la fréquence d'intervention devient infinie. Il est prouvé que cette erreur est bornée par une variable aléatoire proportionnelle au taux de transaction. Cependant, les démonstrations de convergence en probabilité demandent des régularités sur les sensibilités assez restrictives en pratique. Les chapitres suivants contournent ces obstacles en étudiant des convergences presque sûres. Le chapitre 3 développe tout d'abord de nouveaux outils de convergence presque sûre. Ces résultats ont de nombreuses conséquences sur le contrôle presque sûr de martingales et de leur variation quadratique, ainsi que de leurs incréments entre deux temps d'arrêt généraux. Ces résultats de convergence trajectorielle sont connus pour être difficiles à obtenir sans information sur les lois. Par la suite, nous appliquons ces résultats à la minimisation presque sûre de la variation quadratique renormalisée de l'erreur de couverture d'une option de payoff général (cadre multidimensionnel, payoff asiatique, lookback) sur une large classe de temps d'intervention. Une borne inférieure à notre critère est trouvée et une suite minimisante de temps d'arrêt optimale est exhibée : il s'agit de temps d'atteinte d'ellipsoïde aléatoire, dépendant du gamma de l'option. Le chapitre 4 étudie la convergence de l'erreur de couverture d'une option de payoff convexe (dimension 1) en prenant en compte des coûts de transaction à la Leland-Lott. Nous décomposons l'erreur de couverture en une partie martingale et une partie négligeable, puis nous minimisons la variation quadratique de cette martingale sur une classe de temps d'atteintes générales pour des Deltas vérifiant une certaine EDP non-linéaire sur les dérivées secondes. Nous exhibons aussi une suite de temps d'arrêt atteignant cette borne. Des tests numériques illustrent notre approche par rapport à une série de stratégies connues de la littérature. Le chapitre 5 étend le chapitre 3 en considérant une fonctionnelle des variations discrètes d'ordre Y et de Z de deux processus d'Itô Y et Z à valeurs réelles, la minimisation étant sur une large classe de temps d'arrêt servant au calcul des variations discrètes. Borne inférieure et suite minimisant sont obtenues. Une étude numérique sur les coûts de transaction est faite. Le chapitre 6 étudie la discrétisation d'Euler d'un processus multidimensionnel X dirigé par une semi-martingale d'Itô Y . Nous minimisons sur les temps de la grille de discrétisation un critère quadratique sur l'erreur du schéma. Nous trouvons une borne inférieure et une grille optimale, ne dépendant que des données observables. Le chapitre 7 donne un théorème limite centrale pour des discrétisations d'intégrale stochastique sur des grilles de temps d'atteinte d'ellipsoïdes adaptées quelconque. La corrélation limite est conséquence d'asymptotiques fins sur les problèmes de Dirichlet. Dans le chapitre 8, nous nous intéressons aux formules d'expansion pour les options sur spread, pour des modèles à volatilité locale. La clé de l'approche consiste à conserver la propriété de martingale de la moyenne arithmétique et à exploiter la structure du payoff call. Les tests numériques montrent la pertinence de l'approche.
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Lundmark, Karin. "Ögonblickens ömhet : Sune Jonsson i det litterära landskapet." Thesis, Umeå universitet, Institutionen för kultur- och medievetenskaper, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-122297.
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Fridline, Mark M. "Almost Sure Confidence Intervals for the Correlation Coefficient." Cleveland, Ohio : Case Western Reserve University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=case1258999665.
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Thesis(Ph.D.)--Case Western Reserve University, 2010<br>Title from PDF (viewed on 2009-12-22) Department of Statistics Includes abstract Includes bibliographical references and appendices Available online via the OhioLINK ETD Center
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Roy-Chowdhury, Sreemoyee. "Sue Bridehead : a Rorschach test." Thesis, Durham University, 2018. http://etheses.dur.ac.uk/12454/.
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This thesis is a metacritical survey of the criticism on Sue Bridehead’s portrayal in Thomas Hardy’s novel Jude the Obscure, from the time of its publication in 1895 to now, and is intended to be a comprehensive overview and analysis of the major critical lines of enquiry about Sue’s characterisation. Since the scope of this thesis is to engage with over one hundred years of literary criticism, I keep the focus concentrated primarily on the critical responses to the depiction of Sue. I discuss the reasons behind the sustained critical interest in her; and show how she has global appeal in unifying as well as differentiating reader-responses, and opening up new modes of theoretical analysis surrounding the complexity of her representation. The objective of this study is to demonstrate how Sue’s enigmatic characterisation effectually serves the purpose of a Rorschach test. I display how analysing her representation makes readers and critics commit to certain positions. This leads to a plurality in the critical responses - a development that is facilitated by Hardy, who leaves deliberate narrative gaps in the novel. I discuss how this creates the space for the readers to fill the textual gaps with their own presuppositions, and cultural and theoretical beliefs, while analysing Sue’s portrayal. This thesis draws on Hardy’s letters, literary notebooks, and biographies to contextualise the portrayal of Sue, as a supplement to the main body of analysis of the critical material on Sue that is available in book, essay and article forms. Finally, I suggest a way forward in critical studies of Hardy’s works using Sue’s portrayal as a case study through the application of the theoretical framework of ‘transculturalism’. This research seeks to contribute to the body of Hardy scholarship by providing an overview of the existing critical commentary on Sue, while emphasising the ongoing contemporaneity of his most controversial characterisation.
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Berto, Giuliana <1970>. "L'errore e le sue vittime." Master's Degree Thesis, Università Ca' Foscari Venezia, 2020. http://hdl.handle.net/10579/16227.
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Come si può essere nello stesso tempo vittima e artefice di un errore?
Propongo un’analisi antropologica dell’errore umano e delle conseguenze nel professionista che è vittima ed artefice contemporaneamente in ambito sanitario. Si parla dunque di seconda vittima in sanità, dove la prima è il paziente che subisce il danno da una prestazione sanitaria sbagliata, e dove la seconda è il professionista che oltre al grosso impatto emotivo che lo assale dato dai sensi di colpa, in alcuni casi, si trova anche a dover affrontare l’ostilità dei colleghi e superiori. Oggi l’approccio più immediato all’errore e all’evento avverso che ne deriva si focalizza sul comportamento della persona considerato aberrante e la soluzione è la riduzione della variabilità di tale comportamento. Viene messo debolmente sotto analisi il sistema inteso come insieme di elementi umani e tecnologici finalizzati ad un obiettivo comune. Ancor meno viene considerata la prospettiva fenomenologica attraverso l’ascolto dell’esperienza del singolo. Con quest’ultimo approccio, attraverso l’analisi della letteratura nazionale ed internazionale, vorrei che emergesse il vissuto che l’operatore esperisce nel commettere l’ errore anche quando non è derivato danno al paziente, e il segno indelebile che rimane in lui impattando nel futuro professionale e personale.
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Machacuay, Romero Marco Antonio. "El Edificio Nº 9 del asentamiento Chupacigarro, Supe: identificación de un edificio público ceremonial no monumental del arcaico tardío a través de su secuencia arquitectónica." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2008. https://hdl.handle.net/20.500.12672/831.
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Esta investigación aborda los problemas en torno a la caracterización y explicación de la diversidad arquitectónica del Período Arcaico Tardío en el asentamiento Chupacigarro, ubicado en el Valle del río Supe, en la región norcentral de la costa peruana. La investigación forma parte de un esfuerzo por sistematizar los resultados hasta ahora obtenidos en edificios de características públicas y ceremoniales como el Edificio Principal de Chupacigarro. Con fines comparativos emprendemos, en el presente trabajo, la investigación de un tipo de edificio muy frecuente en los asentamientos del Período Arcaico Tardío, que aún no ha recibido la debida atención y que contrasta con sus pares por no haber alcanzado la destacable monumentalidad.
Sustentamos las bases para futuras investigaciones de este y otros tipos de edificios. Abordamos el problema aplicando la metodología clásica de investigación arqueológica ampliada en el marco de conceptos y análisis arquitectónicos, con lo cual buscamos potenciar las interpretaciones que se obtienen de las evidencias estructurales de la edificación y que a su vez nos puedan dar indicios de las relaciones y organización de esta sociedad.
Como resultado hemos determinado que efectivamente, el edificio no monumental estudiado formó parte de un sistema de edificaciones de funciones públicas y ceremoniales relacionadas a la organización social de este asentamiento y como tal comparte muchas de las características generales del sistema pero que, al mismo tiempo, presenta sus propias particularidades.
Se han identificado espacios arquitectónicos que ostentan un manejo de espacios secundarios y que se relacionan a su vez con otros espacios análogos en un juego de relaciones asimétricas.
La organización del espacio arquitectónico de estos edificios elimina el máximo de posibilidades de una libre circulación, lo cual evidencia una actividad principal muy bien constituida, aceptada y desarrollada por esta sociedad.
II
La aceptación de una tipología de edificios y el reconocimiento de un conjunto de unidades arquitectónicas solo pueden ser valoradas en los modelos de relaciones que se establecen entre estas unidades y que son el motivo de su conformación física.
Esta conclusión nos permitirá reconocer que este amplio problema no concluirá con el estudio de uno o dos edificios, sino que estamos ante un trabajo cuyos resultados se obtendrán a largo plazo y de manera sistemática, primero a nivel de asentamiento, luego a nivel de valle y por último a nivel regional.
El desarrollo de este trabajo nos sirve como partida para desarrollar nuestra propuesta y resolver algunas interrogantes planteadas en la problemática.
En el Capítulo 1 realizamos un breve resumen sobre la bibliografía sobre el Período Arcaico Tardío en la que buscamos identificar los edificios similares al estudiado. Indicamos como se ha abordado el tema, ya sea en diferentes aspectos de la cultura social, tecnológicos y económicos. Realizamos además un resumen de las investigaciones en el Valle de Supe, en Caral y en Chupacigarro.
Finalmente, desarrollamos nuestra propuesta sobre la arquitectura, considerada como el elemento cultural por excelencia, y la necesidad de considerarla como el contexto universal que engloba de manera sistemática todos los otros contextos.
En el Capítulo 2, teniendo como base lo anteriormente expuesto, presentamos la problemática afrontada y exponemos el objetivo específico de la investigación, lo cual es lograr una explicación de la estructuración de los componentes del edificio estudiado, de manera sincrónica y diacrónica a través de su secuencia arquitectónica y los contextos asociados, lo cual se traduce en nuestra hipótesis a desarrollar.
III
El Capítulo 3, resume en gran parte nuestra experiencia de trabajo en estos últimos años. Detallamos nuestro enfoque de investigación y los principales aspectos que nos permitirán comprender la estructura, desde los elementos a considerar en la prospección, la excavación y registro hasta algunos conceptos sencillos que sustentan nuestra propuesta arquitectónica y los análisis aplicados a esta secuencia.
En el Capítulo 4, desarrollamos los primeros aspectos mencionados en el capítulo anterior. Damos énfasis a la explicación paisajística del asentamiento, lo cual creemos importante para caracterizar y comprender mejor el edificio. El resultado es en este aspecto un resumen del conocimiento que hemos alcanzado durante los últimos años en este tipo de análisis preliminar y lo presentamos en esta ocasión. En la segunda parte de este capítulo damos cuenta de la excavación del edificio. Como ejemplo, desarrollamos la secuencia el retiro de estratos y contextos de los recintos del lado Oeste del edificio. Hemos escogido esta sección del edificio por la importancia de los contextos hallados y por la complejidad de su deposición. Estas características presentan menos énfasis en otros lados del edificio, por tratarse de una estructura no monumental, o cual puede apreciarse en los diversos dibujos de plantas compuestas y en las secciones presentadas.
En el Capítulo 5, ofrecemos los resultados de nuestra excavación. Para un mejor orden lo hacemos tomando como estructura la secuencia propuesta. En cada fase descrita se detalla la forma del edificio, la técnica constructiva, los contextos asociados y análisis arquitectónico. Se desarrolla además una primera interpretación acompañada de una pequeña discusión. Cuando lo creemos conveniente realizamos un resumen que abarca varias fases, convenientes para exponer mejor nuestras ideas.
En el Capítulo 6, teniendo como base lo expuesto en los capítulos anteriores desplegamos una importante discusión que sustenta nuestras conclusiones.<br>Tesis
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Oubal, Mohamed. "Etude théorique de la réactivité des particules de suie émises par les avions." Besançon, 2011. http://www.theses.fr/2011BESA2042.
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Ce travail concerne la modélisation, à l'échelle moléculaire, des interactions entre certaines espèces atmosphériques et les suies émises par les avions. Il se décompose en plusieurs axes de recherche dont les objectifs étaient d'une part d'avoir une meilleur compréhension des mécanismes de réactivité à la surface des particules carbonées, en particulier vis à vis des oxydants atmosphériques tels qu O,O2,H2O, et certains radicaux comme OH, et d'autre part, d'apporter à la communauté des sciences de l'atmosphère des éléments de compréhension et d'interprétation des propriétés hydrophiles des suies et de leur impact sur la réactivité des molécules d'hydrocarbures polycycliques aromatiques (HAP) dans la troposphère<br>In this work, we presented, a theoretical study, at the molecular level of interactions between atmospheric species and soot particles emitted by aircraft. This work is organized following different axes, the main goals of which being twofold. On the one hand, we aimed at better understanding the mechanisms of reactivity on the surface of carbonaceous particles, in particular toward the aatmospheric oxidants such as O,O2, H2O, and some radicals such as OH. On the other hand, we wanted to give to the atmospheric science community some elements to understand and interpret hydrophilic properties of soot and their impact on the reactivity of molecules of polycyclic aromatic hydrocarbons (PAHS) in the troposphere
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Barakat, Mouhammad Abou-Al-Nasser. "Interaction rayonnement-particules : cas des fumées générées par differents types de combustibles." Poitiers, 1994. http://www.theses.fr/1994POIT2333.
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Mesurer l'opacite d'un milieu gazeux charge en particules, comme des fumees, revient a mesurer l'attenuation que subissent les rayonnements qui le traversent. Toutefois, le principal parametre influencant le parametre d'extinction etant la concentration en particules de suie, il apparait necessaire de definir une grandeur de base (aire specifique d'extinction) liant le coefficient d'extinction a la vitesse de combustion du combustible considere et aux conditions aerauliques par l'intermediaire du debit de fumee. Les combustibles etudies sont, un hydrocarbure d'usage courant (fioul domestique), et des huiles et materiaux de gainage de cables electriques recenses sensibles dans les centrales nucleaires exploitees par edf (organisme partenaire de cette etude). L'influence de la longueur d'onde sur les proprietes d'extinction (coefficient ou aire specifique) est etudiee et les lois de variation, en fonction de ce parametre, sont etablies. Ces lois font ensuite l'objet, apres determination experimentale de la distribution de taille des particules et une recherche detaillee sur le choix des indices optiques, d'une comparaison theorie-experience a partir du calcul des efficacites energetiques d'extinction sur la base des elements de la theorie de mie. Le caractere conservatif de la grandeur aire specifique d'extinction est egalement mis en evidence, en fonction de l'intensite de la combustion et de la dilution des fumees. On procede aussi a une determination indirecte de la taille et de la concentration en particules a partir des mesures realisees a plusieurs longueurs d'onde. Les perspectives d'application a un modele d'analyse d'incendie en compartiment developpe par edf sont ensuite envisagees. Dans ce but, il est procede a la determination d'un parametre d'extinction moyenne sur tout le spectre thermiquement utile. L'ensemble de ce travail permet de tirer un certain nombre d'enseignements sur les aptitudes des differents combustibles consideres a generer des fumees et sur leur potentialite en matiere de rayonnement. Cependant, il conduit parallelement a formuler certaines limites quant a l'exploitation des mesures realisees, que ce soit dans des conditions de ventilation insuffisante des foyers, ou dans des conditions d'evolution granulometrique des particules dans la phase de transport (condensation de vapeurs ou coagulation)
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Moëll, Caroline. "JERSEY, SURE ! : Special developed jersey knits with color effects." Thesis, Högskolan i Borås, Akademin för textil, teknik och ekonomi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-13030.
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This study investigates the effect of single jersey, based on its original formas a cylinder. It is also an investigation of color and transforming surfaceof garment.The outfits are based on the cylinder in construction. With some cuts andseams, developed into garments. The surface of the fabric has qualities recognizable to rib, but the constructionis different. By using cotton and polyester yarns, the stripesshrinks in different directions and when the body integrates with thefabric, shape, gravity and movement will make the material transform byopen and closing the lines. Different color effects are presented in the collection. The result is suggestingdifferent color effects, depending on size of the stripes, the saturationof the colors and the placement on the body.
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Hastings, Susan Elizabeth. "The role of teachers in Sure Start local programmes." Thesis, University of Leicester, 2008. http://hdl.handle.net/2381/4075.
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Sure Start, the national initiative created in 1998 and implemented through local programmes, sought to improve the life chances of children living in areas of deprivation. Children’s services were to be ‘joined up’ to deliver new and different ways of working. The inclusion of teachers was integral to some programmes, although little research was available to document this. This study sets out to examine how teachers responded to the challenge of promoting babies’, toddlers’ and young children’s learning within a multiagency and community context. It investigates how teachers’ roles were constructed; the nature of their everyday activities, how they responded to multi-agency work; how innovative work arose and what triggered change. Qualitative and ethnographic in nature, the study incorporates empirical evidence from six Sure Start Local Programmes (SSLPs). Research methods were designed to access teachers’ thinking within a situated perspective. In addition to work shadowing and scrutiny of documents, data was gathered from 25 semi-structured interviews with team members, managers and teachers. Three complementary theories of social learning; Activity Theory, Communities of Practice and Professional Craft Knowledge, were brought together to interpret findings. Teachers demonstrated varying levels of participation within SSLPs. Those moving towards full participation had undergone identity transformation, and contributed to the construction of a new practitioner: The Sure Start Teacher. Through engagement in front-line joint work with practitioners from other agencies, expansive learning has occurred and this in turn has stimulated innovative practice. The role of teachers in SSLPs can be described as: exchanging knowledge and skills within a multi-agency team; facilitating intergenerational learning in the locality and providing a pedagogic lead within a framework of joint work with members of the Sure Start community.
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Julien, Catherine. "Identidad y filiación por suyu en el Imperio Incaico." Pontificia Universidad Católica del Perú, 2012. http://repositorio.pucp.edu.pe/index/handle/123456789/113399.
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Identity and Suyu Affiliation in the Inca EmpireBy means of two discrete examples, this study attempts to show that the Incas forged imperial identities using the division of Andean space in four suyus, or Tawantinsuyu. In the case of the cult of the sun at Titicaca, groups from all four suyus participated. Through the resettlement of people from all four, the Incas generalized the solar cult to the entire empire. The other case deals with the cults to the snow-covered mountains of Arequipa, called huacas pacariscas. In this instance only mitimaes from the same suyu where the mountain was located participated. It is noteworthy that —as in the region surounding Cuzco— the suyu division in the larger territory was related to sacred places on the landscape, and in the instances explored here, to the most sacred sites in the Andean territory.<br>Mediante dos casos concretos se intenta demostrar que los incas forjaban identidades imperiales en base a la división de su territorio en cuatro suyus, llamada Tawantinsuyu. En el primer caso se trata del culto al Sol en la isla de Titicaca, en el cual participaban mitimaes procedentes de los cuatro suyus. A través de la reubicación de personas procedentes de los cuatro suyus, los incas generalizaron este culto a todo el imperio. El otro caso se refiere al culto rendido a los nevados de Arequipa, llamados huacas pacariscas. Estos cultos fueron mantenidos sólo por mitimaes del suyu en que se ubicaba el nevado, forjando identidades también a un nivel local. Además, hay que destacar que, al igual que en la región del Cuzco, la división en suyus se relacionaba con los lugares sagrados y, en este caso, con los sitios sagrados más importantes del territorio andino.
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Maconochie, Heloise. "Young children's participation in a Sure Start Children's Centre." Thesis, Sheffield Hallam University, 2013. http://shura.shu.ac.uk/7437/.
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Between 2006 and 2010 New Labour launched a network of children's centres as one element in a programme of reform of services for children. Sure Start children's centres were set up as multi-agency settings for children under the age of five and their families. Concomitant with these developments a number of policies converged to give momentum to the notion of children's participation in matters that affect their lives. Political measures included Every Child Matters (DES, 2003) and section 3.5 of the Childcare Act (2006) which stated that local authorities must consider the views of children in relation to early childhood services. Consequently, there was and remains an imperative for children's centres to bring children's perspectives to bear upon their policies and practice, and to ensure that children participate in decisions regarding service design, delivery and evaluation (Sure Start, 2005). Using a methodology that draws upon the traditions of ethnography and participatory action research, this thesis presents an analysis of how the notion of children's participation has been conceptualised, enacted and enhanced in a Phase One children's centre in the North of England across the following services: education and care; family support; child and family health; inclusion and therapy services. Fieldwork was conducted with children, parents and staff of Towersham Park Children's Centre over a twelve month period during 2008-2009 and involved a variety of observational and participatory methods. Previous research about Sure Start predominantly focuses on the effectiveness of programme delivery. However, there is very little research which explores children's participation across a range of children's centre services and includes the perspectives of those who often face barriers to participation, such as babies, preverbal and disabled children and those from ethnic minority and migrant groups. This study addresses these gaps. Research findings suggest that, to understand what young children's participation means in a children's centre context, we need to pay attention to the different socio-spatial domains, cultural-ethical dilemmas and dominant discursive regimes within which participation is situated. Unmasking these domains, dilemmas and discourses enables practitioners to examine their effects of power in constraining and enhancing children's participation and to construct new ways of thinking and being with children. I conclude by arguing that children's participation is as much a micro-political and ethical process of embodied performance in space, as it is a cognitive, discursive activity of children expressing their views and making decisions. These findings have significant implications both for broadening current conceptualisations of participation to make them more inclusive of young, pre-verbal and disabled children and for informing early childhood multi-professional practice to make it more democratic.
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Muller, Gilles. "Conception et realisation d'une machine multiprocesseur sure de fonctionnement." Rennes 1, 1988. http://www.theses.fr/1988REN10044.
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Etude de la conception d'une nouvelle architecture de machines sures de fonctionnement. La caracteristique principale de cette architecture est la possibilite de concevoir une machine sure de fonctionnement a partir d'une ou plusieurs machines standards et d'un composant sur de fonctionnement appele memoire stable
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Nicely, Lindsey. "Applications of Sure Independence Screening Analysis for Supersaturated Designs." VCU Scholars Compass, 2012. http://scholarscompass.vcu.edu/etd/2694.
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Experimental design has applications in many fields, from medicine to manufacturing. Incorporating statistics into both the planning and analysis stages of the experiment will ensure that appropriate data are collected to allow for meaningful analysis and interpretation of the results. If the number of factors of interest is very large, or if the experimental runs are very expensive, then a supersaturated design (SSD) can be used for factor screening. These designs have n runs and k > n - 1 factors, so there are not enough degrees of freedom to allow estimation of all of the main effects. This paper will first review some of the current techniques for the construction and analysis of SSDs, as well as the analysis challenges inherent to SSDs. Analysis techniques of Sure Independence Screening (SIS) and Iterative Sure Independence Screening (ISIS) are discussed, and their applications for SSDs are explored using simulation, in combination with the Smoothly Clipped Absolute Deviation (SCAD) approach for down-selecting and estimating the effects.
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Yang, Zaohui. "Stampa 3D e le sue applicazioni." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2018.
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In questo elaborato sono state messe a confronto le differenti tecnologie di stampa 3D.
Le tecnologie prese in analisi, nello specifico, sono: FDM, la più economica e accessibile;
SLA, la prima stampa in 3D;SLS, l'unico processo per i polimeri senza vincoli di supporto;
stampa a getto di materiale che permette la stampa a colori; stampa a getto di legante, l'unico che non necessita di fonte di calore;DMLS/SLM/EBM che possono produrre pezzi con dettagli finissimi.
Un confronto diretto di queste tecnologie da più punti di vista ha portato ad evidenziare i pregi ed i difetti:sono esaminati i materiali utilizzati, le caratteristiche fisiche e visuali e la capacità del processo.
Infine, una descrizione degli step per stampare un pezzo con una stampante 3D: si crea il modello 3D usando un software CAD; il file così realizzato viene convertito in formato STL; poi Slic3r converte questo file in istruzioni per la stampante, in Gcode.
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Sensolini, Luca. "L'Intelligenza Artificiale e le sue frontiere." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2020.
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La tesi intende proporre un panorama dello stato dell'arte delle Intelligenze Artificiali a cavallo tra il 2019 ed il 2020. Gli obbiettivi di questo sono duplici:
Il primo è una scomposizione storica, filosofica e ingegneristica della materia in modo da essere utile anche a coloro con nessuna esperienza dirette con le I.A. Questo include anche un'analisi dei framework di lavoro più di successo nel campo.
Il secondo è il proporre una dissertazione riguardante lo stato dell'arte I.A. negli ultimi mesi, portando esempi concreti di progetti, aziende e associazioni che hanno espanso gli orizzonti di questo mutevole campo di studio. Questo include un analisi sui limiti riscontrati dai luminari del settore, utile a tracciare un possibile futuro delle I.A.
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Chung, Hyun-Sue. "Hyun-Sue Chung compositions 1996-2001." Thesis, King's College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269750.
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Moioli, Mila <1978>. "Ye Xian e le sue sorelle." Master's Degree Thesis, Università Ca' Foscari Venezia, 2013. http://hdl.handle.net/10579/3417.
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De, Michele Marco <1995>. "L’industria birraria, le sue tendenze di mercato e le sue applicazioni turistiche: il caso Birreria di Pedavena." Master's Degree Thesis, Università Ca' Foscari Venezia, 2022. http://hdl.handle.net/10579/21271.
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Tra i vari, più o meno importanti, settori turistici quello del turismo gastronomico è l’oggetto della prima parte di questo elaborato. Ci si sofferma su definizione, tendenze, opportunità e effetti che globalizzazione e localizzazione hanno su di esso. Rientrante a pieno titolo nel turismo gastronomico ma in una nicchia a sè stante, il turismo della birra è definito come quel turismo in cui la primaria motivazione del viaggiatore è la visita ad una birreria, ad un festival del settore, ad un pub tipico o ad un sito di produzione e/o assaggio delle più svariate tipologie di birra. All’analisi del fenomeno si arriva solo dopo una panoramica sulla storia economica della birra e della sua produzione, oltre che che ad una rassegna del mercato del settore negli ultimi anni, con particolare attenzione all’emergere della birra artigianale come tipologia sempre più apprezzata da consumatori sempre più in cerca di esperienza e qualità. La birra artigianale è anche la tipologia più legata al turismo e allo sviluppo di un'identità gastronomica di destinazione, come emerge dall'analisi della letteratura di settore. Come caso studio nostrano si è deciso di prendere come riferimento la Birreria in Pedavena, la birreria più grande d’Italia. Si parte dalla sua storia, dai fasti iniziali alla crisi a cui seguì l’acquisizione da parte del gruppo Heineken, fino ad arrivare alla mobilitazione operaia per impedirne la chiusura fino al recente acquisto da parte di Birra Castello. Si passa infine ad un’analisi del marketing dell’azienda, che ha permesso lo sviluppo del piccolo paese di Pedavena come destinazione turistica attorno alla storica fabbrica, e al contempo l’esportazione dell’esperienza Pedavena in tutto il Triveneto e non solo, grazie alla catena di ristoranti Fabbrica in Pedavena.
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Noel, Espinoza Arturo Juan. "Investigación arqueológica en un módulo arquitectónico del sector a de Caral. Valle de Supe. Perú." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2004. https://hdl.handle.net/20.500.12672/5797.
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Investigación realizada en uno de los módulos arquitectónicos del Sector A del complejo arqueológico de Caral - Valle de Supe, perteneciente al período Arcaico Tardío (3,000 - 1,800/1500 a. C.). Aporta mayores datos hacia la definición de la organización espacial y a partir de ello, comprender el sistema de circulación interna, tanto del módulo arquitectónico a investigar, así como también del Sector A, para luego plantear inferencias en lo concerniente a las relaciones con las otras edificaciones de Caral. Busca una aproximación a las actividades que se desarrollaron en este tipo de arquitectura no monumental del Sector A de Caral e inferir a que jerarquía social pertenecía este tipo de arquitectura. Enfoca con mayor precisión el aspecto cronológico de las fases arquitectónicas, períodos de remodelación, etc. del módulo arquitectónico a definir en el Sector A. Permite los estudios contrastativos con la arquitectura no monumental e identifica sitios contemporáneos pertenecientes tanto al valle de Supe, como también a otras áreas culturales de los Andes Centrales.<br>Tesis
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Lamharess, Nora. "Etude de la réactivité des suies issues de la combustion des biocarburants : interaction avec le filtre à particules catalysé." Paris 6, 2012. http://www.theses.fr/2012PA066717.
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Cette thèse a pour objectif d’étudier et de comprendre, sur un filtre à particules catalysé commercial, la réactivité des suies issues de la combustion de trois différents carburants : un gazole conventionnel (GO), un mélange de 30% de biodiesel avec du gazole (B30) et un mélange de 30% de gazole de synthèse de type Fischer-tropsch avec du gazole conventionnel (FT30). L’approche repose sur l’utilisation d’un catalyseur de type DPNR (Toyota) afin de réaliser des essais au banc à gaz synthétiques et au banc moteur. Des caractérisations physico-chimiques des suies, du catalyseur et des carburants sont également réalisées afin de mieux comprendre la réactivité de chaque type de suie et de faire le lien entre le carburant et la réactivité catalytique. Il ressort de cette étude que l'utilisation de biocarburants, dans un moteur Diesel, ne devrait pas pénaliser le fonctionnement ni la gestion du filtre à particules catalysé. Le biocarburant de première génération (type biodiesel) serait même bénéfique dans la mesure où la composition des gaz d'échappement qui en résulte est favorable à la régénération continue du filtre à particules catalysé par le NO2 : émissions de suies diminuées et rapport NOx/PM augmenté. Les suies issues du biocarburant de deuxième génération (type Fischer-Tropsch) se sont quant à elles révélées particulièrement réactives dans le cas de la régénération forcée, en présence de NO2 et d'oxygène. Leur oxydation rapide permettrait de diminuer la durée de ce mode de régénération et par là de limiter la surconsommation de carburant qui lui est associée. Les réflexions menées suite aux résultats de cette étude laissent supposer que la suie du B30 est plus avantageuse en termes de régénération continue par le NO2 alors que la suie FT30 est plutôt intéressante pour une régénération par l’oxygène<br>The aims of this thesis is to study and understand, on a CDPF, the reactivity of soots arising from three different biofuels: a classic gasoil (named GO), a blend of 30% of biodiesel with classic gasoil (named B30) and a blend of 30% of Fischer-tropsch gasoil with classic gasoil (named FT30). The approach is based on the use of a commercial catalyst type DPNR of Toyota in order to realize some tests on engine and synthetic gas benches. Characterization tests have also been realized for a better understanding of the reactivity of each soot type. It appears from this study that the use of biofuels in Diesel engines should not penalize the functioning or controlling of the catalyzed particulate filter. The first generation biofuels (B30) is very interesting because the composition of exhaust gases resulting from the combustion of this biofuels is favorable for the continuous regeneration by NO2 (decrees of soot emissions and increase of NOx / PM ratio. The soot from the second-generation biofuel (FT30) has been found very reactive in the case of the forced regeneration in the presence of NO2 and oxygen. The fast oxidation of this soot would reduce the time of this mode of regeneration and thus limits the fuel penalty due to such regeneration. The results of this study suggest that the B30 soot is more interesting on continuous regeneration by NO2 while soot FT30 favors the regeneration by oxygen
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Thangavelu, Karthinathan. "Quantile estimation based on the almost sure central limit theorem." Doctoral thesis, [S.l.] : [s.n.], 2006. http://webdoc.sub.gwdg.de/diss/2006/thangavelu.
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Fang, Youjian. "Transition theorems and almost sure invariance principles for strong martingales." Thesis, University of Ottawa (Canada), 1993. http://hdl.handle.net/10393/6644.
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In this thesis we establish almost sure invariance principles (ASIP's) for strong martingales indexed by two parameters. The method we use is that developed by Berkes and Philipp (Ann. Prob., 7, 1979). This thesis is organized in four chapters. In Chapter 1, we give a review of invariance principles. We introduce the origin of the concept of the invariance principle, describe the main methods for proving the ASIP's and state some basic results of the almost sure invariance principle. In Chapter 2, we prove some "transition theorems" which turn two-parameter strong martingales into one-parameter martingales and can help us to prove the ASIP's for two-parameter strong martingales. We also give several simple applications of the transition theorems, such as maximal inequalities with exponential bounds for two-parameter strong martingales and the Prohorov distance between the law of a two-parameter strong martingale and some appropriate normal law. In Chapter 3, we prove our main theorem--the almost sure invariance principle for two-parameter strong martingales and show some applications, including the functional law of the iterated logarithm for two-parameter strong martingales. In Chapter 4--the appendix, we state some known results we want to use and give the proofs of Theorem 2.2.1 in Chapter 2 and Lemma 3.2.10 in Chapter 3.
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Olausson, Felicia. "En maskulinitetsstudie av tre Sune-filmer : Familjefilm och hegemonisk maktstruktur." Thesis, Örebro universitet, Institutionen för humaniora, utbildnings- och samhällsvetenskap, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-64894.
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Studien är en kvalitativ analys av tre Sune-filmer och bidrar till att bredda kunskapen inom fältet maskulint genus i familjefilm. Till analysen används fyra olika teoretikers texter som stöd för att undersöka hur pojkskap/manlighet/maskulinitet skapas och upprätthålls i filmerna. Analysen är genomförd med hjälp av texter skrivna av Raewyn Connell, Maria Nikolajeva, Daniel Ekman och Magnus Öhrn. Resultatet visar att filmerna kanske inte är traditionellt maskulina, men dominerade av maskulina karaktärsdrag. Många av de maskulina karaktärsdragen som representeras i filmen återfinns i den teoretiska referensramen och det är även tydligt vad som är accepterad och inte accepterat för det manliga könet i filmerna.
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Ana, Frank. "Razvoj metodologije za procenu indikatora u cilju unapređenja klimatološke suše." Phd thesis, Univerzitet u Novom Sadu, Fakultet tehničkih nauka u Novom Sadu, 2016. http://www.cris.uns.ac.rs/record.jsf?recordId=101466&source=NDLTD&language=en.
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U ovoj doktorskoj disertaciji dat je predlog dizajna algoritma i metodologije za procenu indikatora suše – MEPIS. Istraživanje metoda praćenja suše obuhvatilo je tri tradicionalna indikatora i jedan novo formirani. Sve ukupno analizirano je 16 varijacija četiri odabrana indeksa suše period istraživanja obuhvatio je 62 godine, 1951-2012. Analize indikatora ukazale su na opravdanost menjanja pristupa pristupa problematici suše i odstupanja od stohastičkog razmatranja njene pojave i pristupanja termodinamičkim osnovama suše. Modelovanje suše po analogiji sa procesom sušenja vazduhom pokazalo je zadovoljavajuće rezultate i kao agregat ovog pristupa dobijen je IDEA indeks za praćenje uslova koji pogoduju suši. Kao indeks suše koji se striktno bazira na simulaciji fizičkih procesa ukazuje na mogućnost definisanja fizičkog stanja atmosfere koji odgovara stanju suše i korak je ka uniformnoj fizičkoj definiciji suše na osnovu uslova koji je uzrokuju. MEPIS u svojoj punoj formi bi dao dovoljno argumenata da se određeni indeksi koriste operativno i mogao bi opravdati neophodne investicije u tehničke i ljudske resurse.<br>In this doctoral dissertation have been proposed the designs of the algorithm andmethodology for drought indicator assessment –MEPIS. Methods of droughtmonitoring were assessed. Three traditional drought indicators and one newlydeveloped were investigated. In total 16 variations of four selected drought indicatorswere analyzed. Research covered period of 62 years, from 1951-2012. Analyses haveresulted with justification that approach to the drought problem should be changedfrom stochastic to the one based on thermodynamics of drought. Modelling of droughtin analogy with air drying has shown satisfactory results and as an aggregate of thisapproach was obtained IDEA drought indicator. Developed indicator showedsignificant progress in identifying meteorological conditions that favor the developmentof drought. It proves it is possible to define physical conditions that correspond to thestate of drought. It is step forward to uniform definition of drought phenomena. MEPISin its full form would give enough arguments to make decision about usage of testeddrought indicators and could justify the necessary investments in the technical andhuman resources.
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Guedes, Marymarcia. "Suya : a lingua da gente "um estudo fonologico e gramatical"." [s.n.], 1993. http://repositorio.unicamp.br/jspui/handle/REPOSIP/270088.
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Orientador: Luiz Carlos Cagliari<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Estudos da Linguagem<br>Made available in DSpace on 2018-07-18T07:37:54Z (GMT). No. of bitstreams: 1
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Previous issue date: 1993<br>Resumo: A Língua Suyá é falada por cerca de 160 índios que habitam a aldeia Ricô, no Parque Indígena do Xingu, Mato Grosso. Este trabalho tem como objetivo principal o estudo de aspectos da fonologia, da morfologia e da sintaxe do Suyá. Na fonologia, observou-se a existência de alofonia em relação aos fonemas consonantais, característica comum às línguas da Família Jê. A análise morfológica revela que o Suyá apresenta uma série de marcadores de caso, diferenciando-a de outras línguas da mesma família. Quanto à sintaxe, observou-se que o padrão mais recorrente dos constituintes oracionais é SOV. O Suyá apresenta estruturalmente características
pertinentes a línguas aglutinantes, sendo, aparentemente, uma língua "split". Este trabalho se constitui, também, de um panorama das classificações das Línguas da Família Jê, de estudos realizados com outras línguas da mesma família, mais especificamente, o Xavante, o Xerente, o Canela-Krahô, o Kayapó, o Tapayuna, o Apinayé e o Panará e de um panorama dos estudos realizados até o presente momento com a Língua Suyá. Somando-se, ainda, uma breve discussão sobre a questão língual dialeto<br>Abstract: The Suyá consist of an estimated 160 native speakers, living at Ricô village within the Xingu Indigenous Park, Mato Grosso state, Brazil. The purpose of this study, it will be present a description of aspects concerning with the phonologycal, morphologycal, and syntactical structure of the Suyá language. In consonants, the allophonic variations show a complex process quite common to the Jê family's languages. The morphological analysis gives a series of suffixes (case markers) which occur, for example, with noun phrases. This caracteristic distinguishes the Suyá from others languages such as: Xavante, Xerente, Canela-Krahô, Kayapó, Tapayuna, Apinayé, Panará. In the Suyá, the very common basic constituent order is SOV and tAe language presents word structures of the type agglutinating. Some evidences suggest that the Suya is a "split" language. This study shows a brief historical about Jê Family languages classifications and the issues about others Jê Family languages: Xavante, Xerente, Canela-Krahô, Kayapó, Tapayuna, Apinayé, and Panará. It will include a description of the studies realizated with the Suyá until now, and a discution concerning about language/ dialect<br>Doutorado<br>Doutor em Ciências
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Saraiva, Antonio Marcos. "Caracterização funcional e estrutural da nucleotidase SurE de Xyllela fastidiosa." [s.n.], 2009. http://repositorio.unicamp.br/jspui/handle/REPOSIP/316474.
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Orientador: Anete Pereira de Souza<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-14T21:21:36Z (GMT). No. of bitstreams: 1
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Previous issue date: 2009<br>Resumo: A linhagem 9a5c da bactéria Xylella fastidiosa foi o primeiro fitopatógeno a ter seu genoma completamente sequenciado, o qual gerdu diversas informações sobre seu metabolismo e patogenicidade. Das orfs codificadas por esta bactéria, destaca-se; no presente trabalho, a XF0703, cuja proteína correlata (com 28,3 kDa) possui similaridade com proteínas SurE de várias outras bactérias. Proteínas SurEs são nucleotidases que desfosforilam diversos nucleosideos monofosforilados para seus respectivos nucleosideos. Tal função é de fundamental importância para manter o pool balanceado dos quatro (deoxi)ribonucleosideos para síntese de DNA e RNA, respectivamente. Este trabalho descreve a clonagem da orfXF0703 no vetor pET29a, a expressão da proteína recombinante (XfSurE) em Escheríchia coli BL21(DE3) e a purificação da mesma por cromatografia de afinidade ao níquel. A análise da estrutura secundária foi feita por dicroísmo circular e realizou-se a determinação do estado oligomérico por cromatografia de gel filtração e espalhamento de luz a baixo ângulo (SAXS), os quais revelaram que a proteína é um tetrâmero. Dados de caracterização funcional indicam que a proteína possui maior atividade em pH neutro na presença do íon manganês como cofator, com uma maior afinidade pelo substrato 3'-AMP (K0,5=0,16 mM). Além disso, ensaios cinéticos mostram que a proteína possui um comportamento alostérico com alta cooperatividade positiva (coeficiente de Hill em torno de 2,6) com todos os quatro substratos naturais testados (3'-AMP, 5'-dAMP, 5'-AMP e 5-GMP). Experimentos com a técnica de SAXS permitiram calcular o raio de giro (32,7 ± 0.2 A), distância máxima intramolecular (100 A) e a simetria do envelope da molécula (222). A estrutura de diversas SurEs homólogas já cristalizadas foram superpostas ao envelope obtido, sendo que StSurE (SurE de Salmonella com maior idenjidade de aminoácidos) mostrou ter o melhor ajuste. No entanto, notou-se que havia espaços vazios no envelope de XfSurE e tais espaços podiam ser preenchidos a partir do afastamento das alças responsáveis pela tetramerização e pela rotação dos f dímeros. Estes movimentos (translação e rotação) podem explicar o comportamento alostérico da proteína, facilitando a entrada de substrato ao sítio catalítico da molécula.<br>Abstract: The 9a5c strain from bacterium Xylella fastidiosa was the first
phytopathogen to have its genome completely sequenced, which revealed a lot of information about its metabolism and its pathogenicity. 'From a variety of orfs encoded by this bacterium, we highlight, in this work, the XF0703, which correlated protein (with 28.3 kDa) has similarity with SurE proteins from several other bacteria. The SurE proteins *are nucleotidases that dephosphorylate various monophosphorylated nucleosides to their respective nucleosides. This function is critical for maintaining the balanced pool of four (deoxy) ribonucleosides for DNA and RNA synthesis. In this work, we describes the cloning of the XF0703 orf into the vector pET29a, the recombinant protein overexpression (XfSurE) in Escherichia coli
BL21(DE3) and the protein purification by nickel affinity chromatography. The secondary structure analysis was done by circular dichroism, while oligomeric state determination was achieved by gel filtration chromatography and small-angle X-ray light scattering (SAXS), which showed that the protein is a tetramer. Functional characterization data indicate that the protein has a highest activity at neutral pH in the presence of manganese as a cofactor, with a highest affinity for the 3-AMP substrate (K0,5 = 0,16 mM). Furthermore, kinetic tests showed that the protein has a allosteric behavior with a high positive cooperativity (Hill coefficient around 2.6) for all natural substrates screened (3-AMP, 5'-dAMP, 5'-AMP and 5'-GMP). Experiments with SAXS technique have allowed to calculate the radius of gyration (32.7 ± 0.2 A), maximum intramolecular distance (100 A) and molecule symmetry.<br>Doutorado<br>Genetica de Microorganismos<br>Doutor em Genetica e Biologia Molecular
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Bonilla, Heraclio, and Alejandro Rabanal. "La Hacienda San Nicolás (Supe) y la Primera Guerra Mundial." Economía, 2012. http://repositorio.pucp.edu.pe/index/handle/123456789/117505.
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BISCARAT, JEAN-CLAUDE. "Etude de la convergence presque sure d'une classe d'algorithmes stochastiques." Paris 6, 1995. http://www.theses.fr/1995PA066812.
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Dans une premiere partie, nous etablissons la convergence presque sure d'une classe d'algorithmes stochastiques et nous appliquons ce resultat a une version stochastique de l'algorithme e. M. Dans le cadre de l'estimation des parametres d'un melange de distributions de probabilite. Dans une deuxieme partie, nous proposons une nouvelle approche et certaines extensions des resultats de stute (1982) sur les lois du logarithme itere pour les deviations maximales des histogrammes a pas fixe et a pas aleatoire.
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Moreira, Rafael Mascaretti. "SugE: protein involved in TBT resistance in A. molluscorum Av27." Master's thesis, Universidade de Aveiro, 2011. http://hdl.handle.net/10773/7463.
Full textAbstract:
Mestrado em Microbiologia<br>The extensive use of organotin compounds and their subsequent discharge into the environment has led to contamination of marine and freshwater environments. Several studies shown that these compounds are involved in the phenomenon known as "imposex" in gastropods and may affect other organisms, including humans. It is thus of great importance, the removal of these contaminants in ecosystems. It was isolated species of the genus Aeromonas with high resistance to tributyltin (TBT). Aeromonas molluscorum Av27, is able to degrade TBT into less toxic compounds such as dibutyltin (DBT) and monobutyltin (MBT). It was demonstrated that the gene sugE A. molluscorum Av27 (sugE-Av27), was linked to TBT resistance in this strain. This gene codes a protein homologous to SugE, a member of the small multidrug resistance protein family (SMR). Given the possible application of Av27 in bioremediation, it is necessary to study the whole mechanism of resistance and optimize the degradation of TBT in this Av27 strain. Thus, the objectives of this study were: (i) verify the over-expression of SugE A. molluscorum Av27 (SugE-Av27) protein in Av27 in the presence of TBT; (ii) clone Av27-sugE gene into an Escherichia coli expression system, which will allow further purification of the protein for future characterization studies; (iii) development and optimization of a simple and rapid method to evaluate the TBT degradation/toxicity.
In the protein extracts obtained it was not possible to identify the protein SugE-Av27. However, analysis by mass spectrometry, suggested that genes related to protein synthesis, glycolysis and ATP synthesis are being overexpressed in response to TBT exposure. An enzyme, D-alanine-D-alanine ligase, involved in cell wall synthesis, also appears to be overexpressed. Indicating that one of the resistance mechanisms can be related to the maintenance of the cell wall stability.
For the purification of the protein under study, the gene sugE-Av27 was inserted into the vector pET24 and cloned in E.coli BL21 (DE3). After four hours of induction with IPTG, there was an increased expression of SugE-Av27 protein indicated by Western blot analysis.
Micrococcus luteus was shown to be sensitive to TBT, thus can be applied as an indicator species in degradation bioassays of TBT by Av27. It was evidenced a decrease of the TBT toxicity to M. luteus after a period of 54h, therefore this compound is being degraded by Av27.
New perspectives opened up with this work in relation to TBT resistance mechanisms in Av27. To corroborate these results, further studies are needed including an analysis of the genes up- and downregulated in Av27 to TBT exposure and attempt some variations in the physicochemical parameters in the degradation bioassays.<br>O uso extensivo de compostos organostânicos e a sua consequente descarga no ambiente levou à contaminação dos ecossistemas marinhos e de água doce. Vários estudos mostram que estes compostos estão envolvidos no fenómeno conhecido como “Imposex” em gastrópodes e que podem afectar outros organismos, incluindo os seres humanos. É assim, de grande importância, a remoção destes contaminantes dos ecossistemas.
Foi isolada e identificada uma espécie do género Aeromonas com elevada resistência ao tributilestanho (TBT). A estirpe, Aeromonas molluscorum Av27, é capaz de degradar o TBT em compostos menos tóxicos como o dibutilestanho (DBT) e o monobutilestanho (MBT). Foi demonstrado que nesta estirpe o gene sugE A. molluscorum Av27 (sugE-Av27) está implicado na resistência ao TBT. Este gene codifica para uma proteína homóloga à SugE, um membro da família das “small multidrug resistance” (SMR). Dada a possível aplicação de Av27 em processos de biorremediação, torna-se necessário aprofundar o estudo de todo o mecanismo de resistência nesta estirpe, bem como, optimizar o processo de avaliação da degradação do TBT pela estirpe Av27. O presente trabalho teve como objectivos: (i) verificar se, na presença de TBT, o aumento de expressão do gene sugE-Av27 se traduz num aumento da quantidade de proteína; (ii) clonar o gene sugE-Av27 num sistema de expressão em Escherichia coli, para posterior purificação da proteína; (iii) desenvolver e optimizar um método simples e rápido para detectar a degradação do TBT.
Não foi possível identificar a proteína SugE A. molluscorum Av27 (SugE-Av27) nos extractos proteicos. Contudo, da análise por espectrometria de massa, pode-se inferir que outros genes relacionados com a síntese proteica, glicólise e síntese de ATP estão a ser sobrexpressos em resposta à exposição ao TBT. Uma enzima, D-alanina-D-alanina ligase, envolvida na síntese da parede celular, parece estar também a ser sobrexpressa, indicando que um dos mecanismos de resistência possivelmente envolverá a manutenção da estabilidade da parede celular. Com vista à purificação da proteína em estudo, o gene sugE-Av27 foi inserido no vector pET24 e clonado em E. coli BL21 (DE3). Após quatro horas de indução com IPTG verificou-se um aumento da expressão da proteína SugE-Av27, por análise em Western blot.
Na tentativa de desenvolver um método rápido para detecção de TBT em laboratório e sendo Micrococcus luteus sensível ao TBT, utilizou-se está espécie indicadora em bioensaios de degradação do TBT pela Av27. Assim, verificou-se que após um período de 54h a toxicidade do TBT diminuiu, sendo então provável que este composto esteja a ser degradado pela estirpe Av27. No presente trabalho iniciaram-se alguns estudos que poderão, no futuro, contribuir para o esclarecimento do mecanismo de resistência /degradação ao TBT pela estirpe Av27. Contudo, mais estudos são necessários, nomeadamente no que refere à análise da expressão dos genes que estão a ser sub- e sobre-expressos em Av27 em resposta à exposição ao TBT e ainda no que refere ao bioensaio para avaliar a degradação do TBT por Av27.