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Relevant bibliographies by topics / Swertia chirata

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Academic literature on the topic 'Swertia chirata'

Author: Grafiati

Published: 4 June 2025

Last updated: 23 June 2025

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Journal articles on the topic "Swertia chirata"

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MANDAL, SUVRA, PRIYABRATA DASC, ASHES DAS, et al. "EVALUATION OF ANTIOXIDANT ACTIVITY OF THE POLYOXYGENATED XANTHONES FROM SWERTIA CHIRATA BUCH., HAM." Scientific Temper 2, no. 1&2 (2011): 77–80. http://dx.doi.org/10.58414/scientifictemper.2011.02.1.16.

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Swertia chireta is an indigenous medicinal plant which are used for variety of ailments.Moreover, several phytochemicals are present in this plants.The major bioactive compound within the plant is xanthones.This plants are the mojor source of secondary metabolites, like flavonoides and triterpenoid etc . Naturally, the plant Swertia chireta posses a multiple source of different biological componentwhich are solely responsible for different physiological activities. Naturally, bioassay of this plants were investigated with the hexane.Hexan extract of aerial parts of the Himalayan plant, Swertia chirata Buch.Ham. ex Wall.(Gentianaceae) resulted in the isolation of seven polyoxygenated xanthones, fraction Sc-1 – Sc-7. Out of seven compounds extracted from this plant , five components ( Sc - 3 - Sc-7) exhibited antioxidant activity at different magnitude ofpotency.The paper deals with these facts

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Aleem, Abdul, and Hifzul Kabir. "REVIEW ON SWERTIA CHIRATA AS TRADITIONAL USES TO ITS PYHTOCHEMISTRY AND PHRMACOLOGICAL ACTIVITY." Journal of Drug Delivery and Therapeutics 8, no. 5-s (2018): 73–78. http://dx.doi.org/10.22270/jddt.v8i5-s.1957.

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Swertia chirata (Gentianaceae), is a popular medicinal plant native to temperate Himalaya. The plant of Swertia chirata is found at an altitude of 1200-1300m, from Bhutan to Kashmir and in the Khasi hills at 1200-1500m. It also can be grown in sub-temperate territories between 1500-2100m altitudes. Chirata has an erect and about 2-3 ft long stem. Herbal medicinal plants are necessary for about for about 80% of the world population in developed and developing countries for their basic and primary health care required owing to better tolerability, superior empathy with human body and having lesser side effects. Herbal plants are considered as rich source of phytochemical ingredients. The main chemical ingredients are Swertiamarin, Amarogentin, Swechirin, Mangiferin, Sweroside, Gentianine, Amaroswerin, Oleanolic acid, Swertanoone, Ursolic acid. Phytochemical analysis divulges alkaloids, flavonoids, steroids, glycosides, triterpenoids, saponins, xanthones and ascorbic acid in all samples. Nepali S. chirata was found to have finest TLC (thin layer chromatography). People have been using traditional medicinal plants for thousand years ago. Traditional plants play a very important role in preventing and treating of human diseases. Medicinal usage of Swertia chirata is reported in Indian pharmaceutical codex, the American and the British pharmacopoeias and in the different traditional systems of medicine (Unani, Ayurveda and Siddha). Swertia chirata is commonly known as a bitter tonic in traditional system of medicine for the treatment of fever, loss of appetite, digestive disorders, diabetes, skin and various other diseases. Keywords: Swertia chirata, swerchirin, Anti-inflammatory, Oleanolic acid, Traditional medicine.

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Patel, Kanika, Vikas Kumar, Amita Verma, Mahfoozur Rahman, and Dinesh K. Patel. "Amarogentin as Topical Anticancer and Anti-Infective Potential: Scope of Lipid Based Vesicular in its Effective Delivery." Recent Patents on Anti-Infective Drug Discovery 14, no. 1 (2019): 7–15. http://dx.doi.org/10.2174/1574891x13666180913154355.

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There is a need for the development of liposomes based nanomedicines formulation for better efficacy and safety of the available drugs in the market. Liposomes have various applications in the field of pharmaceutical and medical field for their drug target potential, diagnostic importance and imaging techniques. Natural plant based drugs and their derivatives have been used in the medicine, nutraceuticals, perfumery, cosmetic and beverages industry. More than half of the prescribed drugs in the worldwide are mainly derived from different natural sources. Development of plant derived product is an emerging field of food, pharmaceutical and health industries. Plants belonging to the Gentianaecae family are well known for their bitter taste and Swertia chirata is one of best plants among them. Various active phytochemical of Swertia chirata are bitter secoiridoids like gentiopicroside, amarogentin, swertiamarin, isovitexin and isogentisin. People use different species of Swertia in the form of decoction, infusion, paste and juice for the treatment of fever and enteric diseases. Swertia chirata possesses anticarcinogenic, antioxidative, hypoglycemic, antihepatotoxic, antimalarial, anti-inflammatory and antimicrobial activities. Amarogentin, a bitter secoiridoid glycoside present in Swertia chirata plant is an activator of human bitter taste receptor. Pharmacologically, amarogentin has antibacterial, antihepatitis, anticholinergic and chemopreventive activities, moreover, amarogentin has been proven for their anti-lieshmanial activity. Other studies also suggested that amarogentin acts on liver carcinogenesis, skin carcinogenesis and reduced tumour progression. In the present review, we have collected and compiled the data regarding biological sources, ethnomedicinal uses, phytochemistry, anticancer and anti-infective potential of amarogentin. For better understanding of various aspects of amarogentin, we have also discussed Swertia chirayita in a very concise manner. Further data related to various patents on amarogentin have also been discussed in this manuscript. However, we also admit that new advance biological research will also increase the medicinal and pharmacological value of amarogentin. Information regarding the chemistry of amarogentin, its biological sources, bioavailability as a pharmacological agent for the treatment and management of skin disorders and various forms of cancers will be beneficial to the scientists in the medicinal field.

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Patel, Bishun Dayal Prasad, Shyam Babu Yadav, Shiv Mangal Prasad, Kanti Shrestha, Narendranath Tiwari, and Dhanik Lal Bharkher. "Estimation of Amarogentin content and standardization of different samples of Chirata collected from crude drug markets of Nepal." Journal of Ayurveda Campus 2, no. 1 (2021): 1–11. http://dx.doi.org/10.51648/jac.50.

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Background: Amarogentin is a major chemical constituent of bitter principle found in Swertia chirayita (Roxb.ex Fleming) Karsten; family Gentianaceae. Chirata is an endangered species because of it’s over exploitation for pharmaceutical industries. These species are mainly found in the Himalayas and used for gastritis, diabetes, jaundice, urinary disorders, liver disorders, etc. The bitter principle as a main indicator of the medical herb, Nowadays, other species of Swertia are substituted and traded by the name of Chirata. Therefore, the present study was undertaken to estimate Amarogentin and to standardize Chirata samples collected from different markets of Nepal in 2013 A.D. Method and Materials: Different market samples of the species were analyzed for foreign matter, moisture content, extractive values; and bitter principles i.e. Amarogentin by using UFLC at Pacific Analytical Laboratory and Training Center, Lalitpur, Nepal. Result: The findings revealed that foreign matter, moisture content, extractive values; and bitter principles i.e. Amarogentin content varied with different market samples. Methonolic extraction yielded higher percentage of extracts than that of chloroform extraction. Samples including more root and stem, in general, contained higher Amarogentin than samples containing more leaves. The samples containing higher moisture content were lesser in Amarogentin content. The finding of Amarogentin of sample collected from Charikot, Dolkha was 3mg/100gm.Conclusion: In this study, the findings suggest that sample collected from local market of Charikot, Dolkha district was Swertia chirayita and was the best quality.

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Chauhan, Bhupendra, Zulphikar Ali, Md Arif Naseer, and Ranjit Singh. "Pharmacological Activity of a Polyherbal Formulation by Haemoglobin Glycosylation Assay." Journal of Drug Delivery and Therapeutics 9, no. 2 (2019): 57–60. http://dx.doi.org/10.22270/jddt.v9i2.2472.

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Present study involves the development of a polyherbal formulation by using four different herbs i.e. Chirata (Swertia chiratia), Haldi (Curcuma longa), Neem (Azadirachta indica), Gudmar (Gymnema sylvestre), Ashwagandha (Withania somnifera), Gokharu (Pedalium murex), Methi (Trigonella foenum-graecum), Jammun (Syzygium cumini), relating to antidiabetic activity. Freshly collected and authenticated herbs were characterized by studying its morphological and pharmacognostic character. Antidiabetic and antioxidant activity of the formulation was determined by in vitro haemoglobin glycosylation assay and H2O2 radical scavenging method respectively. In the above study it was found that ethanolic extract of polyherbal formulation possess promising antidiabetic and antioxidant activity which can be consider for further biological investigation. Keywords: polyherbal formulation, Swertia chiratia, Curcuma longa, Azadirachta indica, Gymnema sylvestre, Withania somnifera, Pedalium murex, Trigonella foenum-graecum, Syzygium cumini

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Chakravarty, Ajit Kumar, Sibabrata Mukhopadhyay, and Binayak Das. "Swertane triterpenoids from Swertia chirata." Phytochemistry 30, no. 12 (1991): 4087–92. http://dx.doi.org/10.1016/0031-9422(91)83473-x.

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Arjun, Karmakar. "Pharmacognostic and Conservational Overview of Swertia chirata Buch.- Ham. ex Wall., A Critically Endangered Himalayan Herb." Journal of Food Science and Nutrition Therapy 2, no. 1 (2016): 015–18. https://doi.org/10.17352/jfsnt.000004.

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<strong>Background</strong>: Swertia chirata Buch.-Ham. ex Wall. is an endangered medicinal herb native to the temperate Himalayan region. The species holds immense ethnobotanical importance in India, Nepal, Bangladesh and Bhutan. The herb is known to host a plethora of bioactive phytoconstituents that imbue it with a wide variety of medicinal properties. Modern research has proven that extracts of S. chirata possess antioxidative, anticarcinogenic, antimalarial, anti-infl ammatory and hypoglycaemic activities. The present article aims at highlighting the medicinal importance of S. chirata along with a brief discussion about its bioactive phytoconstituents. The research work carried out for improving the germplasm conservation strategies for S. chirata have also been elucidated in this review.

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Bajaj, Sakshi, Vijender Singh, and Mohammed Ali. "New triterpenic compounds from Swertia chirata." Ancient Science of Life 37, no. 1 (2017): 273. http://dx.doi.org/10.4103/asl.asl_5_18.

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Wawrosch, Christoph, Andreas Hugh-Bloch, Kurt Hostettmann, and Brigitte Kopp. "Swertia Chirata Buch.-Ham. ex Wall. (Gentianaceae), an Endanaered Himalavan Medicinal Plant: Comparative Study of the Secondary Compound Patterns in Market Drua. In Vitro-Cultivated, and Micropropaaated Field Qrown Samples." Scientia Pharmaceutica 73, no. 3 (2005): 127–37. http://dx.doi.org/10.3797/scipharm.aut-05-11.

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Samples of the Himalayan medicinal plant Swertia chirata obtained from a local market in Nepal, from a micropropagated field cultivated clone, and from two in vitro-clones were compared by means of HPLC. The substance patterns of methanolic and dichloromethane extracts of the in vivo grown materials showed good conformity while in the samples from tissue culture major compounds were missing. Our findings confirm that the secondary metabolism of in vitro-cultivated plants normally differs from that of plants in their natural environment. Furthermore, the compound pattern of plants produced through micropropagation and subsequently cultivated in the field is comparable to that of plants collected from the wild. As an alternative to the uncontrolled depletion of the natural resources a sustainable use of Swertia chirata could hence be achieved by controlled field culture of micropropagated plants.

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Das, Supradip, Ananta Hembram, Ruma Jas, Mary Sunanda Ganganapalli, Rakibul Haque, and Soumitra Pandit. "Evaluation of the In vitro Anthelmintic Activity of Melia azedarach and Swertia chirata Aqueous Extracts Against Haemonchus contortus." Journal of Advances in Biology & Biotechnology 28, no. 1 (2025): 249–57. https://doi.org/10.9734/jabb/2025/v28i11877.

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Aim: This research intended to assess the in vitro anthelmintic properties of Mahaneem leaves (Melia azedarach) and whole plant of Chirata (Swertia chirata). Study Design: In vitro study was conducted aganist Haemonchus contortus eggs and adult stage by egg hatch assay (EHA) and adult motility inhibition test (AMIT). Place and Duration of Study: This study was conducted in the departement of Veterinary Parasitology, WBUAFS, Kolkata-37 between November,2023 to August, 2024 Methodology: The aqeous extract of Mahaneem and Chirata whole plants were prepared by decoction method, dried and desolved in 2% Dimethyl Sulfoxide to make desirable concentration of extract solutions. Adult Haemonchus contortus was collected from freshly slaughter abomasum of sheep for separation of eggs and active motile adult was used for AMIT. Each EHA and AMIT was performed in triplicate. Results: The results revealed that both Chirata and Mahaneem extracts shows anthelmintic activity against Haemonchus contortus. Chirata extract had better efficacy against both eggs and adult stage of Haemonchus contortus compare to Mahaneem leave extract. In EHA, Chirata extract efficacy at the dose of 50 mg/ml and 25 mg/ml was more statistically significant (p<0.05) than Mahaneem extract. In AMIT, also Chirata shows significantly more efficacy at 50mg/ml and 25 mg/ml than Mahaneem,but at the dose rate of 10 mg Mahaneem shows better efficacy (38.88 2.22) than Chirata (31.11 2.22) extract. At 50 mg/ml concentration after 10 hours of experiment Chirata shows higest efficacy (82.22 2.22) compare to Mahaneem (57.77 2.22). Conclusion: Both Chirata and Mahaneem aqueous extract can potentially be effective against Haemonchus contortus and other GINs in small rumunats when administer properly with selected doses.

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Dissertations / Theses on the topic "Swertia chirata"

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Ali, Rabeia Verfasser], Ludger [Akademischer Betreuer] Beerhues, and Ute [Akademischer Betreuer] [Wittstock. "Molecular Cloning and Functional Characterization of Benzophenone Synthases from Centaurium erythraea and Swertia chirata (Gentianaceae) / Rabeia Ali ; Ludger Beerhues, Ute Wittstock." Braunschweig : Technische Universität Braunschweig, 2019. http://d-nb.info/1189810948/34.

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Pradhan, Sabina. "Studies on physiology and bio chemistry of swertia chirayita (Roxb) karsten in Darjeeling hills: influence of plant growth - substances on growth, metabolism and - yield." Thesis, University of North Bengal, 2015. http://ir.nbu.ac.in/hdl.handle.net/123456789/1846.

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Pradhan, Bharat Kumar. "Population studies and habitat characteristics of swertia chirayita (Roxb. ex Fleming) H. Karst. , a threatened Medicinal Herb in Sikkim Himalaya, and Its Conservation." Thesis, University of North Bengal, 2011. http://hdl.handle.net/123456789/1434.

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Books on the topic "Swertia chirata"

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Maskay, Namita Lal. Micropropagation of the threatened Nepalese medicinal plants Swertia chirata Buch-Ham. ex Wall. and Mahonia napaulensis DC. Chorus, 1996.

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Book chapters on the topic "Swertia chirata"

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Bährle-Rapp, Marina. "Swertia Chirata Extract." In Springer Lexikon Kosmetik und Körperpflege. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_10250.

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Jadhav, Suchita V., Pankaj S. Mundada, Mahendra L. Ahire, Devashree N. Patil, and Swati T. Gurme. "Swertia chirata (Chirata) and Withania somnifera (Ashwagandha)." In Herbs, Shrubs, and Trees of Potential Medicinal Benefits. CRC Press, 2022. http://dx.doi.org/10.1201/9781003205067-15.

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Akbar, Shahid. "Swertia chirata Buck.-Ham. ex Wall. Swertia chirayita (Roxb.) H. Karsten (Gentianaceae)." In Handbook of 200 Medicinal Plants. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-16807-0_176.

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Biswas, Protha, Ikbal Hasan, Shatakshi Mitra, et al. "Swertia chirata Buch.-Ham. Ex Wall., a Traditional Medicinal Plant with Antidiabetic Potential." In Antidiabetic Medicinal Plants and Herbal Treatments. CRC Press, 2023. http://dx.doi.org/10.1201/b23347-16.

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Koul, Sushma, K. A. Suri, P. Dutt, M. Sambyal, A. Ahuja, and M. K. Kaul. "Protocol for In Vitro Regeneration and Marker Glycoside Assessment in Swertia chirata Buch-Ham." In Methods in Molecular Biology. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-287-2_12.

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Mazumder, Md Anisur Rahman, Md Fahad Jubayer, Mohammad Javed Ansari, and Thottiam Vasudevan Ranganathan. "Swertia chirayita (Roxb. ex Flem.): Chirayata/Chiretta." In Immunity Boosting Medicinal Plants of the Western Himalayas. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-9501-9_21.

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Chouhan, Rekha, Natish Kumar, Amit Kumar, Sajad Ahmed, Yadunandan Sen, and Sumit G. Gandhi. "Establishment of Hairy Roots of Endangered Himalayan Plant Swertia chirata: A Sustainable Alternative to Extraction from Nature." In Hairy Root Cultures Based Applications. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-4055-4_4.

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Dev, Sukh. "Swertia chirayita." In Prime Ayurvedic Plant Drugs. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-22075-3_93.

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Timilsina, Bishnu, Rabindra Parajuli, Dilli Prasad Rijal, et al. "Swertia angustifolia Burkill Swertia chirayita Buch.-Ham. ex C.B. Clarke Swertia cordata (G.Don) Clarke Swertia petiolata D. Don Gentianaceae." In Ethnobotany of the Himalayas. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-45597-2_237-1.

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Jan, Hammad Ahmad, Wahid Hussain, Rainer W. Bussmann, and Narel Y. Paniagua-Zambrana. "Swertia angustifolia Burkill Swertia chirayita Buch.-Ham. ex C.B. Clarke Swertia cordata (G.Don) Clarke Swertia petiolata D. Don Gentianaceae." In Ethnobotany of the Himalayas. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-45597-2_237-2.

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Conference papers on the topic "Swertia chirata"

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Rutz, Adriano, Pascale Deneulin, Ivano Tonutti, Benoît Bach, and Jean-Luc Wolfender. "Untargeted chemical and sensory characterization of Swertia chirayita: a bitter case study." In GA – 69th Annual Meeting 2021, Virtual conference. Georg Thieme Verlag, 2021. http://dx.doi.org/10.1055/s-0041-1736968.

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