Log in

Relevant bibliographies by topics / Swine Animal Model / Journal articles

To see the other types of publications on this topic, follow the link: Swine Animal Model.

Journal articles on the topic 'Swine Animal Model'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Swine Animal Model.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

LELOVAS (Π. ΛΕΛΟΒΑΣ), P., K. MARINOU (Κ. ΜΑΡΙΝΟΥ), Th XANTHOS (Θ. ΞΑΝΘΟΣ), D. PAPADIMITRIOU (Δ. ΠΑΠΑΔΗΜΗΤΡΙΟΥ), D. PERREA (Δ. ΠΕΡΡΕΑ), and I. DONTAS (Ι. ΔΟΝΤΑ). "Swine as an animal model of cardiopulmonary resuscitation." Journal of the Hellenic Veterinary Medical Society 57, no. 1 (2017): 27. http://dx.doi.org/10.12681/jhvms.15007.

Full text

Abstract:

This paper reviews the advantages of swine in relation to other animal models of cardiopulmonary resuscitation referred to in the literature. The causes of cardiac arrest and the difficulties raised during research in humans are presented. All animal models used in this particular field are discussed and a detailed review is performed regarding the major anatomical and physiological similarities between swine and man, as well as the experimental studies published in the international literature.

APA, Harvard, Vancouver, ISO, and other styles

2

Yoganandan, Narayan, Alok Shah, Jamie Baisden, et al. "Matched-pair hybrid test paradigm for behind armor blunt trauma using an experimental animal model." Trauma Surgery & Acute Care Open 9, no. 1 (2024): e001194. http://dx.doi.org/10.1136/tsaco-2023-001194.

Full text

Abstract:

BackgroundThe current behind armor blunt trauma (BABT) injury criterion uses a single penetration limit of 44 mm in Roma Plastilina clay and is not specific to thoracoabdominal regions. However, different regions in the human body have different injury tolerances. This manuscript presents a matched-pair hybrid test paradigm with different experimental models and candidate metrics to develop regional human injury criteria.MethodsLive and cadaver swine were used as matched pair experimental models. An impactor simulating backface deformation profiles produced by body armor from military-relevant

APA, Harvard, Vancouver, ISO, and other styles

3

Huang, Christene A., Yasushi Fuchimoto, Zachary L. Gleit, et al. "Posttransplantation lymphoproliferative disease in miniature swine after allogeneic hematopoietic cell transplantation: similarity to human PTLD and association with a porcine gammaherpesvirus." Blood 97, no. 5 (2001): 1467–73. http://dx.doi.org/10.1182/blood.v97.5.1467.

Full text

Abstract:

Posttransplantation lymphoproliferative disease (PTLD) is a major complication of current clinical transplantation regimens. The lack of a reproducible large-animal model of PTLD has limited progress in understanding the pathogenesis of and in developing therapy for this clinically important disease. This study found a high incidence of PTLD in miniature swine undergoing allogeneic hematopoietic stem cell transplantation and characterized this disease in swine. Two days before allogeneic peripheral blood stem cell transplantation, miniature swine were conditioned with thymic irradiation and in

APA, Harvard, Vancouver, ISO, and other styles

4

XANTHOS (Θ. ΞΑΝΘΟΣ), Th. "Swine model in cardiopulmonary resuscitation research." Journal of the Hellenic Veterinary Medical Society 60, no. 3 (2017): 254. http://dx.doi.org/10.12681/jhvms.14935.

Full text

Abstract:

Cardiac Arrest (CA) constitutes a real medical emergency. Various experimental models have been developed in order to test experimental treatments. Animal models that have been used in CA research are rodents, rabbits, cats and dogs, primates and swine. Among these, swine are used more often. The reason behind this choice is mostly its close resemblance to the human cardiac anatomy and physiology. Various haemodynamic variables have been investigated as predictors of the return of spontaneous circulation (ROSC). Coronary Perfusion Pressure (CPP) is the only proven predictor for ROSC. CPP, whic

APA, Harvard, Vancouver, ISO, and other styles

5

Navarro-Alvarez, Nalú, Beatriz M. M. Gonçalves, Alec R. Andrews, David H. Sachs, and Christene A. Huang. "A CFA-Induced Model of Inflammatory Skin Disease in Miniature Swine." International Journal of Inflammation 2018 (June 24, 2018): 1–8. http://dx.doi.org/10.1155/2018/6916920.

Full text

Abstract:

Similarities between porcine and human skin make the pig an ideal model for preclinical studies of cutaneous inflammation and wound healing. Complete Freund’s adjuvant (CFA) has been used to induce inflammation and to study inflammatory pain in several animal models. Here, we evaluated the inflammation caused by CFA injected in different layers of skin and subcutaneous (SC) tissue in a large-animal model. The degree of inflammation was evaluated at early and late time points by visual inspection and histopathologic analysis. In addition, the side effects of CFA injections were evaluated based

APA, Harvard, Vancouver, ISO, and other styles

6

Guo, Xiaomei, Bhavesh Patel, Ling Han, et al. "Novel swine model of colonic diverticulosis." American Journal of Physiology-Gastrointestinal and Liver Physiology 317, no. 1 (2019): G51—G56. http://dx.doi.org/10.1152/ajpgi.00408.2018.

Full text

Abstract:

The pathophysiology of colonic diverticulosis has not been completely understood. The development of appropriate animal models is essential to study diverticular disease. To date, no large animal models are available for this disease condition. The objective of this study was to develop a swine model by damaging the colon wall, combined with or without a low-fiber diet to mimic the pathogenesis of diverticulosis. To create a weakness on the colon wall, collagenase was applied in vivo to degrade the collagen in the colon wall. Three groups of Yucatan minipigs were included. Group 1 ( n = 12) un

APA, Harvard, Vancouver, ISO, and other styles

7

KUDO, Hideyuki, Motoyuki KATAOKA, Hiroshi IRIE, et al. "Acceleration of Atherogenesis in Hyperinsulinemic Miniature Swine Animal Model." Journal of Japan Atherosclerosis Society 24, no. 10 (1997): 501–4. http://dx.doi.org/10.5551/jat1973.24.10_501.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Zhang, Zhang, Shigeho Takarada, and Sabee Molloi. "Assessment of coronary microcirculation in a swine animal model." American Journal of Physiology-Heart and Circulatory Physiology 301, no. 2 (2011): H402—H408. http://dx.doi.org/10.1152/ajpheart.00213.2011.

Full text

Abstract:

Coronary microvascular dysfunction has important prognostic implications. Several hemodynamic indexes, such as coronary flow reserve (CFR), microvascular resistance, and zero-flow pressure (Pzf), were used to establish the most reliable index to assess coronary microcirculation. Fifteen swine were instrumented with a flow probe, and a pressure wire was advanced into the distal left anterior descending artery. Adenosine was used to produce maximum hyperemia. Microspheres were used to create microvascular dysfunction. An occluder was used to produce stenosis. Blood flow from the probe (Q̇p), aor

APA, Harvard, Vancouver, ISO, and other styles

9

Misfeldt, M. L., and D. R. Grimm. "Sinclair miniature swine: an animal model of human melanoma." Veterinary Immunology and Immunopathology 43, no. 1-3 (1994): 167–75. http://dx.doi.org/10.1016/0165-2427(94)90133-3.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Micsa, C., D. Togoe, V. A. Dutulescu, et al. "Training in laparoscopic biliary procedures in swine animal model." Journal of Biotechnology 305 (November 2019): S82. http://dx.doi.org/10.1016/j.jbiotec.2019.05.283.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Zhao, Huihui, Jianxin Chen, Qi Shi, et al. "Metabolomics-Based Study of Clinical and Animal Plasma Samples in Coronary Heart Disease with Blood Stasis Syndrome." Evidence-Based Complementary and Alternative Medicine 2012 (2012): 1–6. http://dx.doi.org/10.1155/2012/638723.

Full text

Abstract:

The aim of this study is to explore a bridge connecting the mechanism basis and macro syndromes of coronary heart disease with experimental animal models. GC-MS technique was used to detect the metabolites of plasma samples in mini swine models with myocardial infarction (MI) and patients with unstable angina (UA). 30 metabolites were detected in the plasma samples of more than 50 percent of model group and control group in swine, while 37 metabolites were found in the plasma samples of UA patients and healthy control group. 21 metabolites in the plasma samples of swine model and 20 metabolite

APA, Harvard, Vancouver, ISO, and other styles

12

Kőrösi, Dénes, András Vorobcsuk, Dániel Fajtai, Ottó Tátrai, Emőke Bodor, and Rita Garamvölgyi. "Closed-chest occlusion of the left anterior descending artery in swine infarction model." Acta Agraria Kaposváriensis 27, no. 1-2 (2023): 77–85. http://dx.doi.org/10.31914/aak.3423.

Full text

Abstract:

Pigs have played a significant role in biological and medical research for many years. In the case of non-rodent models, pigs are the primary choices as experimental animals in the cardiovascular studies. Accumulating data indicate that the closed-chest coronary balloon-occlusion technique is one of the most successful method for creating ischemic heart failure (HF). However, consistent and thoroughly characterized large animal models of HF are a critical translational tool for drug development and toxicology. The knowledge of the different catheterization protocols is crucial to ensure a suit

APA, Harvard, Vancouver, ISO, and other styles

13

Sreenivasan, Chithra, Milton Thomas, Zizhang Sheng, et al. "Replication and Transmission of the Novel Bovine Influenza D Virus in a Guinea Pig Model." Journal of Virology 89, no. 23 (2015): 11990–2001. http://dx.doi.org/10.1128/jvi.01630-15.

Full text

Abstract:

ABSTRACTInfluenza D virus (FLUDV) is a novel influenza virus that infects cattle and swine. The goal of this study was to investigate the replication and transmission of bovine FLUDV in guinea pigs. Following direct intranasal inoculation of animals, the virus was detected in nasal washes of infected animals during the first 7 days postinfection. High viral titers were obtained from nasal turbinates and lung tissues of directly inoculated animals. Further, bovine FLUDV was able to transmit from the infected guinea pigs to sentinel animals by means of contact and not by aerosol dissemination un

APA, Harvard, Vancouver, ISO, and other styles

14

Jogler, Christian, Dennis Hoffmann, Dirk Theegarten, Thomas Grunwald, Klaus Überla, and Oliver Wildner. "Replication Properties of Human Adenovirus In Vivo and in Cultures of Primary Cells from Different Animal Species." Journal of Virology 80, no. 7 (2006): 3549–58. http://dx.doi.org/10.1128/jvi.80.7.3549-3558.2006.

Full text

Abstract:

ABSTRACT Oncolytic adenoviruses have emerged as a promising approach for the treatment of tumors resistant to other treatment modalities. However, preclinical safety studies are hampered by the lack of a permissive nonhuman host. Screening of a panel of primary cell cultures from seven different animal species revealed that porcine cells support productive replication of human adenovirus type 5 (Ad5) nearly as efficiently as human A549 cells, while release of infectious virus by cells from other animal species tested was diminished by several orders of magnitude. Restriction of productive Ad5

APA, Harvard, Vancouver, ISO, and other styles

15

XANTHOS (Θ. ΞΑΝΘΟΣ), T., E. BASSIAKOU (Ε. ΜΠΑΣΙΑΚΟΥ), D. PAPADIMITRIOU (Δ. ΠΑΠΑΔΗΜΗΤΡΙΟΥ), E. KOUDOUNA (Ε. ΚΟΥΔΟΥΝΑ), P. LELOVAS (Π. ΛΕΛΟΒΑΣ), and L. PAPADIMITRIOU (Λ. ΠΑΠΑΔΗΜΗΤΡΙΟΥ). "Cardiopulmonary resuscitation in a swine model of cardiac arrest." Journal of the Hellenic Veterinary Medical Society 58, no. 3 (2017): 232. http://dx.doi.org/10.12681/jhvms.14988.

Full text

Abstract:

Introduction: Cardiac arrest (CA) is a daunting medical emergency. In order to answer various questions regarding CA, and furthermore to implement novel therapeutic strategies, various animal models have been used.Aim: The aim of the present study is to describe the experimental model of CA and cardiopulmonary resuscitation (CPR), developed in our department.Materials and methods: Twenty pigs were anaesthetized and intubated. The internal jugular veins were surgically prepared, together with the carotid artery. Ventricular fibrillation (VF) was induced with an ordinary lithium battery through

APA, Harvard, Vancouver, ISO, and other styles

16

Helm, Ricki M., and A. Wesley Burks. "Sensitization and Allergic Response and Intervention Therapy in Animal Models." Journal of AOAC INTERNATIONAL 87, no. 6 (2004): 1441–47. http://dx.doi.org/10.1093/jaoac/87.6.1441.

Full text

Abstract:

Abstract A review is presented of 3 murine models and a swine neonatal model used to investigate immunotherapeutic options. In Model 1, mutation of linear IgE-binding epitopes of Ara h 1 for the preparation of a hypoallergenic Ara h 1 is discussed with respect to expression in transgenic tobacco plants and correct folding following expression in the pET16b construct. In Model 2, the mutations of Ara h 1 were assessed for use as an immunotherapeutic agent. Although some protective benefit was observed with the modified Ara h 1 protein, animals desensitized with heat-killed E. coli preparations

APA, Harvard, Vancouver, ISO, and other styles

17

NIELSEN, J. P., T. S. LARSEN, T. HALASA, and L. E. CHRISTIANSEN. "Estimation of the transmission dynamics of African swine fever virus within a swine house." Epidemiology and Infection 145, no. 13 (2017): 2787–96. http://dx.doi.org/10.1017/s0950268817001613.

Full text

Abstract:

SUMMARYThe spread of African swine fever virus (ASFV) threatens to reach further parts of Europe. In countries with a large swine production, an outbreak of ASF may result in devastating economic consequences for the swine industry. Simulation models can assist decision makers setting up contingency plans. This creates a need for estimation of parameters. This study presents a new analysis of a previously published study. A full likelihood framework is presented including the impact of model assumptions on the estimated transmission parameters. As animals were only tested every other day, an i

APA, Harvard, Vancouver, ISO, and other styles

18

Siegel, Julianne, and Ron Kolata. "Endometriosis Model Development in Swine." Lab Animal 32, no. 4 (2003): 41–45. http://dx.doi.org/10.1038/laban0403-41.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Ramirez, Brett C., Guoming Li, Yijie Xiong, Robert T. Burns, and Richard S. Gates. "Evaluating Draft EPA Swine Emission Models – Part I: Facilities." Journal of the ASABE 68, no. 2 (2025): 267–84. https://doi.org/10.13031/ja.16204.

Full text

Abstract:

HighlightsDraft EPA emission models for swine facilities were systematically evaluated.Draft EPA models performed poorly on estimating pollutant emissions when input variables were outside of NAEMS data.An unanticipated sensitivity of the draft EPA model outputs to pig inventory and climate was identified.Draft EPA models may need further revision and improvement before being adopted by the swine industry.ABSTRACT. In August 2021, the United States (U.S.) Environmental Protection Agency (EPA) released draft models to estimate daily NH3, H2S, PM10, PM2.5, and TSP emissions from breeding/gestati

APA, Harvard, Vancouver, ISO, and other styles

20

Gómez-Segura, Lidia, Antoni Boix-Montañes, Mireia Mallandrich, et al. "Swine as the Animal Model for Testing New Formulations of Anti-Inflammatory Drugs: Carprofen Pharmacokinetics and Bioavailability of the Intramuscular Route." Pharmaceutics 14, no. 5 (2022): 1045. http://dx.doi.org/10.3390/pharmaceutics14051045.

Full text

Abstract:

Carprofen (CP) is a non-steroidal anti-inflammatory drug (NSAID) frequently used to treat respiratory diseases in numerous small animals, but also in large species. CP is a formidable candidate for further therapeutic research of human inflammatory diseases using the pig as an animal model. However, CP administration in swine is very uncommon and respective pharmacokinetics/bioavailability studies are scarce. A simultaneous population pharmacokinetic analysis after CP intravenous and intramuscular administrations in pigs has shown high extent and rate of absorption and a similar distribution p

APA, Harvard, Vancouver, ISO, and other styles

21

Hu, Yaguan, and Yanli Yu. "Scale Difference from the Impact of Disease Control on Pig Production Efficiency." Animals 12, no. 19 (2022): 2647. http://dx.doi.org/10.3390/ani12192647.

Full text

Abstract:

Epidemic disease prevention plays a critical role in ensuring the healthy development of livestock farming, and the subjective willingness of breeders can be affected by the cost of epidemic disease prevention. To correct the misconception that farmers regard the cost of disease control as an ineffective cost, and to promote the healthy development of the pig breeding industry, our study employed the data envelopment analysis super-efficiency model and panel threshold regression model to evaluate the combination of the cost of epidemic disease prevention and swine productivity using data colle

APA, Harvard, Vancouver, ISO, and other styles

22

Taiyeb, Ahmed M., Saeeda A. Muhsen-Alanssari, Duane C. Kraemer, Olivia Ash, Virginia Fajt, and Mundhir T. Ridha-Albarzanchi. "Cilostazol blocks pregnancy in naturally cycling swine: An animal model." Life Sciences 142 (December 2015): 92–96. http://dx.doi.org/10.1016/j.lfs.2015.10.017.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Holanda, Mônica Calixto Ribeiro de, Marco Aurélio Carneiro de Holanda, and Leandro Ricardo Rodrigues de Lucena. "Relation between swine weight and morphometric measurements." Research, Society and Development 9, no. 9 (2020): e891998013. http://dx.doi.org/10.33448/rsd-v9i9.8013.

Full text

Abstract:

Objective was to define a mathematical model that better explain the relationship of the animals weight depending not only on the animals age but also on the animals morphometric measurements. 40 piglets, half Duroc-Large White blood, were used, 20 males and 20 females, from 3 to 35 days of age (lactation phase) initially weighing 1.518 ± 0.121 kg and from 36 to 66 days of age (calving phase) with a body weight of 7.010 ± 0.704 kg. The animals were weighed weekly on a digital balance. The relationship of animal weight, age and morphometric measurements of male and female piglets were performed

APA, Harvard, Vancouver, ISO, and other styles

24

HanBayer, Junjie. "316 Awardee Talk: Development and Assessment of Predictive Models for Improved Swine Farming." Journal of Animal Science 101, Supplement_2 (2023): 22–23. http://dx.doi.org/10.1093/jas/skad341.024.

Full text

Abstract:

Abstract Prediction of outcomes is critical in swine breeding and management. This necessitates the development of predictive models that address challenges in swine farming. For predictive modeling, there have been significant advances in machine learning. Nevertheless, there are needs to adapt predictive models for specific swine farming problems including genomic prediction and behavior analysis. Furthermore, there is not yet a clear guideline on how to validate novel models in these fields. The overarching goal of this work was to validate a collection of predictive models for improved swi

APA, Harvard, Vancouver, ISO, and other styles

25

Rudar, Marko, Marta L. Fiorotto, and Teresa A. Davis. "Regulation of Muscle Growth in Early Postnatal Life in a Swine Model." Annual Review of Animal Biosciences 7, no. 1 (2019): 309–35. http://dx.doi.org/10.1146/annurev-animal-020518-115130.

Full text

Abstract:

Skeletal muscle growth during the early postnatal period is rapid in the pig and dependent on the capacity of muscle to respond to anabolic and catabolic stimuli. Muscle mass is driven by the balance between protein synthesis and degradation. Among these processes, muscle protein synthesis in the piglet is exceptionally sensitive to the feeding-induced postprandial changes in insulin and amino acids, whereas muscle protein degradation is affected only during specific catabolic states. The developmental decline in the response of muscle to feeding is associated with changes in the signaling pat

APA, Harvard, Vancouver, ISO, and other styles

26

Hernandez-Torres, Sofia I., Emily N. Boice, and Eric J. Snider. "Using an Ultrasound Tissue Phantom Model for Hybrid Training of Deep Learning Models for Shrapnel Detection." Journal of Imaging 8, no. 10 (2022): 270. http://dx.doi.org/10.3390/jimaging8100270.

Full text

Abstract:

Tissue phantoms are important for medical research to reduce the use of animal or human tissue when testing or troubleshooting new devices or technology. Development of machine-learning detection tools that rely on large ultrasound imaging data sets can potentially be streamlined with high quality phantoms that closely mimic important features of biological tissue. Here, we demonstrate how an ultrasound-compliant tissue phantom comprised of multiple layers of gelatin to mimic bone, fat, and muscle tissue types can be used for machine-learning training. This tissue phantom has a heterogeneous c

APA, Harvard, Vancouver, ISO, and other styles

27

Gory, B., D. Bresson, A. Rouchaud, C. Yardin, and C. Mounayer. "A Novel Swine Model to Evaluate Arterial Vessel Injury after Mechanical Endovascular Thrombectomy." Interventional Neuroradiology 19, no. 2 (2013): 147–52. http://dx.doi.org/10.1177/159101991301900201.

Full text

Abstract:

Few animal models have been reported to evaluate and compare mechanical endovascular thrombectomy (MET) devices used to treat human ischemic stroke. These models may contribute to the understanding of arterial injury induced by a MET device and potentially by extrapolation to human intracranial arteries. We have developed a novel swine model for MET that allows visualization of the thrombus/device interaction and characterization of mechanical impact on the vessel wall. Twenty superficial femoral arteries were occluded with radiopaque thrombus, and 20 without thrombus were treated with thrombe

APA, Harvard, Vancouver, ISO, and other styles

28

Walters, Eric M., Melissa S. Samuel, Kevin D. Wells, Lela K. Riley, and Randall S. Prather. "THE PIG AS A BIOMEDICAL MODEL: HOW THE NATIONAL SWINE RESOURCE AND RESEARCH CENTER CAN HELP YOU." Reproduction, Fertility and Development 24, no. 1 (2012): 284. http://dx.doi.org/10.1071/rdv24n1ab242.

Full text

Abstract:

Swine are an excellent large animal model for human health and disease because their size and physiology are similar to humans, and the progression of many diseases, such as cardiovascular disease, is similar to humans. Due to these similarities, technology, procedures, and novel treatments that have been developed for human diseases can be applied to swine, and vice versa. In addition there are some human diseases, such as cystic fibrosis, that don't recapitulate in the rodent models but are well modeled in swine. Swine have been accepted as the model of choice for several medical application

APA, Harvard, Vancouver, ISO, and other styles

29

Zhang, J. J., X. K. Meng, C. Dong, et al. "Development of a New Animal Model of Liver Cirrhosis in Swine." European Surgical Research 42, no. 1 (2009): 35–39. http://dx.doi.org/10.1159/000167855.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Yamada, Kazuhiko, Pierre R. Gianello, Francesco L. Ierino, et al. "Role of the Thymus in Transplantation Tolerance in Miniature Swine. I. Requirement of the Thymus for Rapid and Stable Induction of Tolerance to Class I–mismatched Renal Allografts." Journal of Experimental Medicine 186, no. 4 (1997): 497–506. http://dx.doi.org/10.1084/jem.186.4.497.

Full text

Abstract:

The almost uniform failure in transplant patients of tolerance-inducing regimens that have been found to be effective in rodents, has made it necessary to examine large animal models before testing of new approaches clinically. Miniature swine have been shown to share many relevant immunologic parameters with humans, and because of their reproducible genetics, have proved extremely useful in providing such a large animal model. We have previously shown that indefinite systemic tolerance to renal allografts in miniature swine is induced in 100% of cases across a two-haplotype class I plus minor

APA, Harvard, Vancouver, ISO, and other styles

31

Kolczewski, P., M. Barwijuk, M. Parafiniuk, et al. "Noninvasive bipolar radiofrequency - vaginal application on swine model." Journal of Applied Cosmetology 42, no. 1 (2024): 22/39. http://dx.doi.org/10.56609/jac.v42i1.340.

Full text

Abstract:

The aim of the study was to evaluate the concentration of collagen and elastin fibers, the number of fibroblasts/fibrocytes and vessels, as well as depth of action in the vaginal wall in a swine model before and after intravaginal 480 kHz bipolar radiofrequency heating created by a 360-degree intravaginal applicator (Berger and Kraft Medical). Three swine’s were treated with a bipolar radiofrequency vaginal probe. Exposure to RF was administered twice, every 4 weeks, and then the vaginas were removed after slaughter, four weeks after the last RF exposure. Histology specimens were obtained from

APA, Harvard, Vancouver, ISO, and other styles

32

Andrade, Almir Ferreira de, Matheus Schmidt Soares, Gustavo Cartaxo Patriota, et al. "Experimental model of intracranial hypertension with continuous multiparametric monitoring in swine." Arquivos de Neuro-Psiquiatria 71, no. 10 (2013): 802–6. http://dx.doi.org/10.1590/0004-282x20130126.

Full text

Abstract:

Objective Intracranial hypertension (IH) develops in approximately 50% of all patients with severe traumatic brain injury (TBI). Therefore, it is very important to identify a suitable animal model to study and understand the pathophysiology of refractory IH to develop effective treatments. Methods We describe a new experimental porcine model designed to simulate expansive brain hematoma causing IH. Under anesthesia, IH was simulated with a balloon insufflation. The IH variables were measured with intracranial pressure (ICP) parenchymal monitoring, epidural, cerebral oximetry, and transcranial

APA, Harvard, Vancouver, ISO, and other styles

33

Bae, Kyoung-Hee, Sang Hyun Park, Byung-Cheon Lee, et al. "Novel Threadlike Structures May Be Present on the Large Animal Organ Surface: Evidence in Swine Model." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/758763.

Full text

Abstract:

Background. The types of embryonic development probably provoke different paths of novel threadlike structure (NTS) development. The authors hypothesized that NTS may be easily observed on the surface of swine intestines by using trypan blue staining method and visualization under an optical microscope.Methods. General anesthesia was administered to 2 Yorkshire pigs. The abdominal walls of the pigs were carefully dissected along the medial alba. NTSs were identified on organ surfaces under a stereoscopic microscope after trypan blue staining. Isolated NTS specimens obtained from the large inte

APA, Harvard, Vancouver, ISO, and other styles

34

Yang, Qihui, Beatriz Martínez-López, Sifat Afroj Moon, Jose Pablo Gomez-Vazquez, and Caterina Scoglio. "Animal movement estimation and network-based epidemic modeling: Illustration for the swine industry in Iowa (US)." PLOS One 20, no. 6 (2025): e0326234. https://doi.org/10.1371/journal.pone.0326234.

Full text

Abstract:

Animal movement plays a critical role in disease transmission between farms. However, in the United States, the lack of available animal shipment data, sometimes coupled with a lack of detailed information about farm demographics and characteristics, presents great challenges for epidemic modeling and prediction. In this study, we proposed a new method based on the maximum entropy to generate “synthetic” animal movement networks, considering available statistics about the premises operation type, operation size, and the distance between premises. We illustrated our method for the swine movemen

APA, Harvard, Vancouver, ISO, and other styles

35

Dzięgiel, Natalia, Paulina Szczurek, Jacek Jura, and Marek Pieszka. "The pig as an animal model in biomedical research: A review." Postępy Higieny i Medycyny Doświadczalnej 72 (December 11, 2018): 1032–42. http://dx.doi.org/10.5604/01.3001.0012.7815.

Full text

Abstract:

The advances in translational biomedical research, especially in genetic engineering, created new opportunities to trace the courses of human diseases and develop effective therapeutic methods. There remains, however, a growing demand for appropriate animal models for the precise evaluation of the efficacy and safety of new drugs or therapeutic concepts. Thus far, rodent models have been most widely used in translational research; however, since they do not perfectly reflect the human disease phenotype, transgenic pigs are increasingly being utilized as animal models. Thanks to the anatomical

APA, Harvard, Vancouver, ISO, and other styles

36

Reynolds, Penny S., Jacquelyn McCarter, Christopher Sweeney, et al. "Informing efficient pilot development of animal trauma models through quality improvement strategies." Laboratory Animals 53, no. 4 (2018): 394–404. http://dx.doi.org/10.1177/0023677218802999.

Full text

Abstract:

Poor quality data in preclinical trials can result from inconsistent and unstandardized experimental processes. Unpredictable pre-intervention variability generates unreliable data, biases outcomes and results in needless waste of animals and resources. We applied Define-Measure-Analyse-Improve-Control (DMAIC) quality improvement processes to pilot development of a swine model of trauma, haemorrhagic shock and coagulopathy. The goal was to reduce variability through protocol standardization and error reduction. Six male Sinclair swine were sequentially anesthetized, intubated, mechanically ven

APA, Harvard, Vancouver, ISO, and other styles

37

Craig, B. A., and A. P. Schinckel. "Nonlinear Mixed Effects Model for Swine Growth." Professional Animal Scientist 17, no. 4 (2001): 256–60. http://dx.doi.org/10.15232/s1080-7446(15)31637-5.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Gong, Joshua, and Chengbo Yang. "396 Gaps and tips in the development of probiotics for swine production." Journal of Animal Science 98, Supplement_4 (2020): 182. http://dx.doi.org/10.1093/jas/skaa278.335.

Full text

Abstract:

Abstract Probiotics have long been used in food animal production to improve animal health and nutrition. This practice has received an extensive interest after European Union countries restricted the use of antibiotics as animal growth promoters (AGP). Although probiotics have good potential to replace AGPs by offering various benefits to animal hosts in general, their efficacy and consistency remain to be a challenge in application. Developing scientific evidence-based probiotics is thus critical to resolve the issue. The current presentation points out the major gaps in the development and

APA, Harvard, Vancouver, ISO, and other styles

39

Karnachuk, Olga V., Alexey V. Beletsky, Andrey L. Rakitin, et al. "Antibiotic-Resistant Desulfovibrio Produces H2S from Supplements for Animal Farming." Microorganisms 11, no. 4 (2023): 838. http://dx.doi.org/10.3390/microorganisms11040838.

Full text

Abstract:

Sulphate-reducing bacteria, primarily Desulfovibrio, are responsible for the active generation of H2S in swine production waste. The model species for sulphate reduction studies, Desulfovibrio vulgaris strain L2, was previously isolated from swine manure characterized by high rates of dissimilatory sulphate reduction. The source of electron acceptors in low-sulphate swine waste for the high rate of H2S formation remains uncertain. Here, we demonstrate the ability of the L2 strain to use common animal farming supplements including L-lysine-sulphate, gypsum and gypsum plasterboards as electron a

APA, Harvard, Vancouver, ISO, and other styles

40

Chade, Alejandro R., Maxx L. Williams, Jason Engel, Erika Guise, and Taylor W. Harvey. "A translational model of chronic kidney disease in swine." American Journal of Physiology-Renal Physiology 315, no. 2 (2018): F364—F373. http://dx.doi.org/10.1152/ajprenal.00063.2018.

Full text

Abstract:

Animal models of chronic kidney disease (CKD) are critical for understanding its pathophysiology and for therapeutic development. The cardiovascular and renal anatomy and physiology of the pig are virtually identical to humans. This study aimed to develop a novel translational model of CKD that mimics the pathological features of CKD in humans. CKD was induced in seven domestic pigs by bilateral renal artery stenosis and diet-induced dyslipidemia. Animals were observed for a total of 14 wk. Renal hemodynamics and function were quantified in vivo using multi-detector CT after 6, 10, and 14 wk o

APA, Harvard, Vancouver, ISO, and other styles

41

Mathern, Nathalie, Ehsan Yousefian, Hani Ridwan, Omid Nikoubashman, and Martin Wiesmann. "Comparison of porcine and human vascular diameters for the optimization of interventional stroke training and research." PLOS ONE 17, no. 5 (2022): e0268005. http://dx.doi.org/10.1371/journal.pone.0268005.

Full text

Abstract:

The branches of the porcine subclavian artery are frequently used in endovascular stroke training and research. This study aimed to determine a porcine weight group, in which the arterial diameters most closely match human cerebral artery diameters, and thus optimize the porcine in-vivo model for neuroendovascular purposes. A group of 42 German Landrace swine (45–74 kg) was divided into four subgroups according to their weight. Angiographic images of the swine were used to determine the arterial diameter of the main branches of the subclavian artery: axillary artery, brachial artery, external

APA, Harvard, Vancouver, ISO, and other styles

42

Friess, S. H., M. Y. Naim, T. J. Kilbaugh, J. Ralston, and S. S. Margulies. "Premedication with meloxicam exacerbates intracranial haemorrhage in an immature swine model of non-impact inertial head injury." Laboratory Animals 46, no. 2 (2012): 164–66. http://dx.doi.org/10.1258/la.2011.011084.

Full text

Abstract:

Meloxicam is a cyclo-oxygenase-2 (COX-2) preferential non-steroidal anti-inflammatory drug with very effective analgesic and anti-inflammatory effects in swine. Previous reports in piglets have demonstrated that meloxicam also inhibits COX-1 and reduces production of thromboxane significantly. We use preinjury analgesia in our immature swine (3–5-day-old piglets) model of brain injury using rapid head rotations without impact. In 23 consecutive subjects we found that premedication with meloxicam ( n = 6) produced a significantly higher mortality rate (5/6 or 83%) than buprenorphine ( n = 17, 1

APA, Harvard, Vancouver, ISO, and other styles

43

Xanthos, T., P. Lelovas, I. Vlachos, et al. "Cardiopulmonary arrest and resuscitation in Landrace/Large White swine: a research model." Laboratory Animals 41, no. 3 (2007): 353–62. http://dx.doi.org/10.1258/002367707781282820.

Full text

Abstract:

Sudden cardiac death (SCD) is a field of continuous research. In order to answer various questions regarding SCD, several animal models have been developed. The aim of the present study is to describe our experimental model of inducing cardiac arrest in Landrace/Large White pigs, and then resuscitated according to the International Guidelines on resuscitation. Fifteen Landrace/Large White pigs were anaesthetized and intubated while spontaneously breathing. The left and right jugular veins, as well as the femoral and the carotid arteries, were surgically prepared. Induction of cardiac arrest wa

APA, Harvard, Vancouver, ISO, and other styles

44

Ku, JC, Y. Dobashi, CR Pasarikovski, et al. "P.191 Development and Testing of a Novel Hydrogel Embolization Treatment for Neurovascular Diseases: Preliminary Animal Results." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 48, s3 (2021): S75. http://dx.doi.org/10.1017/cjn.2021.467.

Full text

Abstract:

Background: Embolization represents a minimally invasive treatment modality for arteriovenous malformations (AVMs), tumors, aneurysms, and vessel sacrifice, but can be limited by currently available embolization agents. Discovery of new and improved agents could lead to better treatment outcomes. The goal of this project was to develop and test a novel embolization agent using hydrogels, a class of materials which may be bioengineered to suit a variety of indications. Methods: We devised a method of liquid hydrogel embolization with photo-modulated crosslinking for intravascular solidification

APA, Harvard, Vancouver, ISO, and other styles

45

Fuchimoto, Yasushi, Kazuhiko Yamada, Akira Shimizu, et al. "Relationship Between Chimerism and Tolerance in a Kidney Transplantation Model." Journal of Immunology 162, no. 10 (1999): 5704–11. http://dx.doi.org/10.4049/jimmunol.162.10.5704.

Full text

Abstract:

Abstract The persistence of donor leukocytes in recipients of organ allografts has been associated with long-term graft acceptance. However, it remains unclear whether this peripheral donor cell microchimerism plays an active role in graft acceptance or is simply a consequence of the maintenance of sufficient immunosuppression to avoid rejection. A model of kidney transplantation between swine leukocyte Ag (SLA)-matched miniature swine, in which tolerance can be established with or without immunosuppressive treatment, has been used to study the correlation between donor leukocyte chimerism and

APA, Harvard, Vancouver, ISO, and other styles

46

Mabry, J. W., and M. T. See. "Selection with the Animal Model Versus Selection Within Contemporary Groups for Swine." Journal of Dairy Science 73, no. 9 (1990): 2657–65. http://dx.doi.org/10.3168/jds.s0022-0302(90)78951-5.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Carl, S., J. Voegele, G. Staehler, and M. Wiesel. "Kidney splitting in miniature swine: a new animal model in renal transplantation." Transplantation Proceedings 32, no. 4 (2000): 800–801. http://dx.doi.org/10.1016/s0041-1345(00)00988-x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Mohan, K., N. Shridhar, S. G. Ramachandra, T. V. Shiva Shankar, B. H. Pavithra, and B. Venkanna. "Mini-pigs as replacement for non-rodent species." Journal of Laboratory Animal Science 1, no. 2 (2019): 42–46. https://doi.org/10.48165/jlas.2019.1.2.9.

Full text

Abstract:

Swine is the optimal model species for investigation of a large number of human diseases and have made valuable contributions to almost every field of human medicine. Similarities in the cardiovascular, urogenital, integument, skeletal and digestive systems of swine to humans have contributed to increased use of pigs in research. Swine offer additional advantages over other species by having a renal anatomy and function very similar to human. Studies have lead to the development of a highly warranted vaccine for various diseases using swine as model. In animal models, whole cell vaccination re

APA, Harvard, Vancouver, ISO, and other styles

49

Falach, Reut, Anita Sapoznikov, Yentl Evgy, et al. "Post-Exposure Anti-Ricin Treatment Protects Swine against Lethal Systemic and Pulmonary Exposures." Toxins 12, no. 6 (2020): 354. http://dx.doi.org/10.3390/toxins12060354.

Full text

Abstract:

Ricin, a plant-derived toxin originating from the seeds of Ricinus communis (castor bean plant), is one of the most lethal toxins known. To date, there is no approved post-exposure therapy for ricin exposures. This work demonstrates for the first time the therapeutic efficacy of equine-derived anti-ricin F(ab’)2 antibodies against lethal pulmonary and systemic ricin exposures in swine. While administration of the antitoxin at 18 h post-exposure protected more than 80% of both intratracheally and intramuscularly ricin-intoxicated swine, treatment at 24 h post-exposure protected 58% of the intra

APA, Harvard, Vancouver, ISO, and other styles

50

Pandian, Vinciya, William Robert Leeper, Christian Jones, et al. "Comparison of surgical cricothyroidotomy training: a randomized controlled trial of a swine model versus an animated robotic manikin model." Trauma Surgery & Acute Care Open 5, no. 1 (2020): e000431. http://dx.doi.org/10.1136/tsaco-2019-000431.

Full text

Abstract:

BackgroundAirway obstruction remains a preventable cause of death on the battlefield. Surgical cricothyroidotomy is an essential skill for immediate airway management in trauma. Training for surgical cricothyroidotomy has been undertaken using simulators, cadavers or animal models. The ideal approach to training for this low volume and high-risk procedure is unknown. We hypothesized that current simulation technology provides an equal or better education for surgical cricothyroidotomy when compared with animal tissue training.MethodsWe performed a prospective randomized controlled study compar

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!