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Journal articles on the topic 'Syloid'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Yaroshenko, A. O., та O. S. Shpychak. "Обґрунтування вибору носія для субстанції калини звичайної плодів екстракту рідкого у складі таблеток «Вібурнікор»". Ukrainian Journal of Military Medicine 4, № 3 (2023): 123–31. http://dx.doi.org/10.46847/ujmm.2023.3(4)-123.

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Мета. Обґрунтування вибору носія для субстанції калини звичайної плодів екстракту рідкого (КЗПЕР) у складі розроблюваних таблеток під умовною назвою «Вібурнікор» мембраностабілізувальної та кардіопротекторної. Матеріали та методи. У роботі були використані фізико‐хімічні, фармако-технологічні та статистичні методи аналізу. Як активний фармацевтичний інгредієнт було обрано калини звичайної плодів екстракт рідкий та дозволені до медичного застосування допоміжні речовини. Таблетки отримували методом прямого пресування. Дослідження впливу допоміжних речовин на фармако-технологічні характерис

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Szentmihályi, Klára, Szilvia Klébert, Krisztina Móricz, et al. "Immobilization of Levocetirizine on Mesoporous Silica for Antiallergenic Gel Formulation." Applied Sciences 14, no. 20 (2024): 9605. http://dx.doi.org/10.3390/app14209605.

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Levocetirizine dihydrochloride is an effective antiallergenic drug applied mostly orally; however, developing a topical formulation for localized treatment could be beneficial. To achieve this, a modified formulation technique is necessary to enhance bioavailability efficiency and minimize possible side effects. Therefore, levocetirizine particles were prepared by immobilization on mesoporous silica material. Both the dihydrochloride form and its free base of levocetirizine were fixed on a silica-type Syloid support. Immobilization of the active ingredient levocetirizine in a free base form on

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3

Kapourani, Afroditi, Konstantinos Katopodis, Vasiliki Valkanioti, Melina Chatzitheodoridou, Christos Cholevas, and Panagiotis Barmpalexis. "Evaluation of Suitable Polymeric Matrix/Carriers during Loading of Poorly Water Soluble Drugs onto Mesoporous Silica: Physical Stability and In Vitro Supersaturation." Polymers 16, no. 6 (2024): 802. http://dx.doi.org/10.3390/polym16060802.

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The application of mesoporous carriers in formulations of amorphous solid dispersions (ASDs) has been suggested to enhance the stability of amorphous drugs. However, mesoporous carriers do not demonstrate satisfactory inhibitory effects on the precipitation of active pharmaceutical ingredients (APIs), and the inclusion of an appropriate polymer within ASDs becomes imperative to maintaining drug supersaturation. The aim of this study was to evaluate ternary olanzapine (OLN) ASDs with Syloid 244FP and to find an appropriate polymeric carrier. The polymer’s selection criteria were based on the ph

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4

Maslii, Yuliia, Оlena Ruban, and Sergiy Kutsenko. "SELECTION OF FLAVOUR ADDITIVES AND METHOD OF THEIR INTRODUCTION IN THE COMPOSITION OF COMPRESSED MEDICATED CHEWING GUMS." EUREKA: Health Sciences 2 (March 31, 2020): 59–66. http://dx.doi.org/10.21303/2504-5679.2020.001189.

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An important characteristic of oral medicines, which include medicated chewing gums, is their pleasant taste. This can be achieved by adding taste coregents to their composition. The aim: to choose rational flavour additives and justify the method of their introduction to the compressed medicated chewing gums that are being developed. Materials and methods: mint (Natural Mint Flavor SD, Kerry Inc., Malaysia), apple (Nat Apple FlavorWonf, Kerry Inc., Malaysia) and banana (Banana FLV, Kerry Inc., Malaysia) have been used as powdered flavour additives. As flavourings – oil solutions: Peppermint N

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5

Klapiszewski, Łukasz, Jakub Zdarta, Tomasz Szatkowski, et al. "Silica/lignosulfonate hybrid materials: Preparation and characterization." Open Chemistry 12, no. 6 (2014): 719–35. http://dx.doi.org/10.2478/s11532-014-0523-5.

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AbstractThe research reported here concerns the synthesis, characterization and potential applications of silica/lignosulfonate hybrid materials. Three types of silica were used (Aerosil®200, Syloid®244 and hydrated silica), along with magnesium lignosulfonate. The effectiveness of the hybrid material synthesis methodology was confirmed indirectly, using Fourier transform infrared spectroscopy, elemental and colorimetric analysis. Dispersive-morphological analysis indicates that the products with the best properties were obtained using 10 parts by weight of magnesium lignosulfonate per 100 par

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Knapik-Kowalczuk, Justyna, Daniel Kramarczyk, Krzysztof Chmiel, Jana Romanova, Kohsaku Kawakami, and Marian Paluch. "Importance of Mesoporous Silica Particle Size in the Stabilization of Amorphous Pharmaceuticals—The Case of Simvastatin." Pharmaceutics 12, no. 4 (2020): 384. http://dx.doi.org/10.3390/pharmaceutics12040384.

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In this paper, the role of mesoporous silica (MS) particle size in the stabilization of amorphous simvastatin (SVT) is revealed. For inhibiting recrystallization of the supercooled drug, the two MS materials (Syloid® XDP 3050 and Syloid® 244 FP) were employed. The crystallization tendency of SVT alone and in mixture with the MS materials was investigated by Differential Scanning Calorimetry (DSC) and Broadband Dielectric Spectroscopy (BDS). Neither confinement of the SVT molecules inside the MS pores nor molecular interactions between functional groups of the SVT molecules and the surface of t

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7

Yuliia, Maslii, Ruban Olena, and Kutsenko Sergiy. "SELECTION OF FLAVOUR ADDITIVES AND METHOD OF THEIR INTRODUCTION IN THE COMPOSITION OF COMPRESSED MEDICATED CHEWING GUMS." EUREKA: Health Sciences 2 (March 31, 2020): 59–66. https://doi.org/10.21303/2504-5679.2020.001189.

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An important characteristic of oral medicines, which include medicated chewing gums, is their pleasant taste. This can be achieved by adding taste coregents to their composition. <strong>The aim:</strong><strong> </strong>to choose rational flavour additives and justify the method of their introduction to the compressed medicated chewing gums that are being developed. <strong>Materials and methods:</strong> mint (Natural Mint Flavor SD, Kerry Inc., Malaysia), apple (Nat Apple FlavorWonf, Kerry Inc., Malaysia) and banana (Banana FLV, Kerry Inc., Malaysia) have been used as powdered fl

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8

Gerashchenko, I. I., I. I. Voitko, and A. V. Vasilieva. "Structural and adsorptive properties of silica-alumina and clay materials of mineral and synthetic origin." Farmatsevtychnyi zhurnal, no. 1 (February 12, 2019): 63–69. http://dx.doi.org/10.32352/0367-3057.1.15.05.

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Location on territory of Ukraine of great deposits of aluminosilicates together with good facilities for their processing and standardization promotes the study of this raw material, results of which could be useful for the developers of enterosorbents. For search the specific sorptive activity a comparative examination of several materials of silica-alumina and clay nature has been carried out in this work. The X-ray phase analysis, a measuring of specific surface area by the low temperature adsorption–desorption of nitrogen and the method of isotherm of adsorption have been used.

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Kovačević, Mila, Ilija German Ilić, Katarina Bolko Seljak, and Alenka Zvonar Pobirk. "High-Shear Wet Granulation of SMEDDS Based on Mesoporous Carriers for Improved Carvedilol Solubility." Pharmaceutics 14, no. 10 (2022): 2077. http://dx.doi.org/10.3390/pharmaceutics14102077.

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Mesoporous carriers are a convenient choice for the solidification of self-microemulsifying drug delivery systems (SMEDDS) designed to improve the solubility of poorly water-soluble drugs. They are known for high liquid load capacity and the ability to maintain characteristics of dry, free-flowing powders. Therefore, five different mesoporous carriers were used for the preparation of carvedilol-loaded SMEDDS granules by wet granulation methods—in paten (manually) and using a high-shear (HS) granulator. Granules with the highest SMEDDS content (63% and 66% of total granules mass, respectively)

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Szentmihályi, Klára, Szilvia Klébert, Zoltán May, et al. "Immobilization of Metronidazole on Mesoporous Silica Materials." Pharmaceutics 14, no. 11 (2022): 2332. http://dx.doi.org/10.3390/pharmaceutics14112332.

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Metronidazole (MTZ) is a widely used drug, but due to its many side effects, there is a growing trend today to use a minimum dose while maintaining high efficacy. One way to meet this demand is to reduce the size of the drug particles. A relatively new method of size reduction is attaching the drug molecules to a mesoporous carrier. In this paper, we studied the fixation of MTZ molecules on mesoporous silica carriers. The drug was immobilized on two mesoporous silica materials (Syloid, SBA-15) with the use of a variety of immersion techniques and solvents. The immobilized drug was subjected to

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11

Elbl, Jan, Martin Veselý, Dagmar Blaháčková, et al. "Development of 3D Printed Multi-Layered Orodispersible Films with Porous Structure Applicable as a Substrate for Inkjet Printing." Pharmaceutics 15, no. 2 (2023): 714. http://dx.doi.org/10.3390/pharmaceutics15020714.

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The direct tailoring of the size, composition, or number of layers belongs to the advantages of 3D printing employment in producing orodispersible films (ODFs) compared to the frequently utilized solvent casting method. This study aimed to produce porous ODFs as a substrate for medicated ink deposited by a 2D printer. The innovative semi-solid extrusion 3D printing method was employed to produce multilayered ODFs, where the bottom layer assures the mechanical properties. In contrast, the top layer provides a porous structure for ink entrapment. Hydroxypropyl methylcellulose and polyvinyl alcoh

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Garapati, Supriya, Ch Santhi, and Pentyala Suneetha. "THE SYLOID PROCESS: MORPHOMETRY AND ITS CLINICAL IMPLICATIONS IN COSTAL REGION OF ANDRAPRADESH, INDIA." International Journal of Anatomy and Research 5, no. 2.2 (2017): 3796–99. http://dx.doi.org/10.16965/ijar.2017.181.

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13

Schroeder, Paul C., M. Teresa Aguado, Allyson Malpartida, and Christopher J. Glasby. "New observations on reproduction in the branching polychaetes Ramisyllis multicaudata and Syllis ramosa (Annelida: Syllidae: Syllinae)." Journal of the Marine Biological Association of the United Kingdom 97, no. 5 (2017): 1167–75. http://dx.doi.org/10.1017/s002531541700039x.

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Reproduction in the shallow-water, sponge-dwelling, branching syllid Ramisyllis multicaudata exhibits several features unique among syllids and among annelids in general. We describe and illustrate the segmental asymmetry which intervenes between regions of symmetry, only found in branching annelids. We describe the morphology of the stolons and of the stolon stalks, which are unique to branching syllids but differ in detail from those of the other known branching syllid, Syllis ramosa. We also illustrate newly found paddle-shaped chaetae, which might indicate that these stolons do swim. We li

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Asim, Muhammad, Marriam Nazir, Zunera Chauhdary, et al. "Enhanced Solubility and Biological Activity of Dexibuprofen-Loaded Silica-Based Ternary Solid Dispersions." Pharmaceutics 15, no. 2 (2023): 399. http://dx.doi.org/10.3390/pharmaceutics15020399.

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The current study was designed to formulate ternary solid dispersions (TSDs) of dexibuprofen (Dex) by solvent evaporation to augment the solubility and dissolution profile, in turn providing gastric protection and effective anti-inflammatory activity. Initially, nine formulations (S1 to S9) of binary solid dispersions (BSDs) were developed. Formulation S1 comprising a 1:1 weight ratio of Dex and Syloid 244FP® was chosen as the optimum BSD formulation due to its better solubility profile. Afterward, 20 TSD formulations were developed using the optimum BSD. The formulation containing Syloid 244F

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Husuzade, Günay, Burcu Mesut, and Sevgi Güngor. "Development of a Solid-Type IV Self-Emulsifying Drug Delivery System of BCS Class II Drug." Proceedings 78, no. 1 (2020): 32. http://dx.doi.org/10.3390/iecp2020-08670.

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Self-emulsifying systems (SEEDS) are becoming increasingly popular for the preparation of oral dosage forms of low-water-soluble drugs. SEEDS are divided into subgroups according to their components; type IV formulations that are prepared using only surfactants and/or co-surfactants. The aim of the study was to increase the solubility of tadalafil, a class II drug according to the BCS, by preparing a type IV formulation. In the study, Labrasol, Kolliphor PS 20, Kolliphor PS 60, Kolliphor PS 80, Kolliphor CS 12, Kolliphor CS 20, Kolliphor HS 15, Kolliphor EL, Kolliphor ELP, Kolliphor PEG400, Ge

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Hespeler, David, Sanaa El Nomeiri, Jonas Kaltenbach, and Rainer H. Müller. "Nanoporous smartPearls for dermal application – Identification of optimal silica types and a scalable production process as prerequisites for marketed products." Beilstein Journal of Nanotechnology 10 (August 8, 2019): 1666–78. http://dx.doi.org/10.3762/bjnano.10.162.

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smartPearls are a dermal delivery system for poorly soluble active agents, consisting of nanoporous silica particles loaded with a long-term stable, amorphous active agent in its mesopores (2–50 nm). The amorphous state of the active agent is known to increase dermal bioavailability. For use in marketed products, optimal silica types were identified from commercially available, regulatory accepted silica. In addition, a scalable production process was demonstrated. The loading of the particles was performed by applying the immersion–evaporation method. The antioxidant rutin was used as a model

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Rolon, Miriam, Eustine Hanna, Celeste Vega, et al. "Solid Nanomedicines of Nifurtimox and Benznidazole for the Oral Treatment of Chagas Disease." Pharmaceutics 14, no. 9 (2022): 1822. http://dx.doi.org/10.3390/pharmaceutics14091822.

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Chagas disease (CD) is a parasitic zoonosis endemic in Central and South America affecting nearly 10 million people, with 100 million people at high risk of contracting the disease. Treatment is only effective when received at the early stages of the disease and it involved two drugs (nifurtimox (NFX) and benznidazole (BNZ)). Both treatments require multiple daily administrations of high doses, suffer from variable efficacy and insufficient efficacy in chronic CD, many side effects, and a very long duration of treatment that results in poor compliance, while combined available therapies that l

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Zolotov, S. A., N. B. Demina, E. S. Ponomarev, I. A. Dain, and A. S. Zolotova. "Study of the Technological Methods Effect on Dissolution of the X-ray Amorphous Efavirenz-mesoporous Carrier System." Drug development & registration 11, no. 3 (2022): 84–89. http://dx.doi.org/10.33380/2305-2066-2022-11-3-84-89.

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Introduction. The low solubility of active pharmaceutical ingredients (APIs) in the physiological pH range of the intestinal tract can adversely affect their absorption and bioavailability. Various methods of increasing the solubility of APIs have been proposed in recent decades. Among them there are preparation of solid dispersions, micronization, solubilization and other methods, including ones based on the amorphization of the crystalline substances, such as, spray drying, hot melt extrusion, absorption on mesoporous carriers such as magnesium aluminosilicate, silica, etc.Aim. Study the tec

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Waters, Laura J., John P. Hanrahan, Joseph M. Tobin, et al. "Enhancing the dissolution of phenylbutazone using Syloid® based mesoporous silicas for oral equine applications." Journal of Pharmaceutical Analysis 8, no. 3 (2018): 181–86. http://dx.doi.org/10.1016/j.jpha.2018.01.004.

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Jesionowski, Teofil, Monika Pokora, Kinga Sobaszkiewicz, and Juliusz Pernak. "Preparation and characterization of functionalized precipitated silica SYLOID®244 using ionic liquids as modifiers." Surface and Interface Analysis 36, no. 11 (2004): 1491–96. http://dx.doi.org/10.1002/sia.1927.

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Sarker, Bakul, Mariele Fligge, Tanja Knaab, and Jörg Breitkreutz. "Implementation of a New Electronic Liquid Dispensing System for Individualized Compounding of Hard Capsules." Pharmaceutics 14, no. 8 (2022): 1580. http://dx.doi.org/10.3390/pharmaceutics14081580.

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An automated compounding device can be a useful tool for the rapid and accurate production of small batches for personalized medicine as well as for clinical batches. A novel electronic liquid dispensing system (ELDS) was investigated to produce hard capsules with individualized dose strengths. An ethanol-based solvent system containing the antihypertensive enalapril maleate was extruded through a cannula into prefilled capsules. The capsules were prefilled with a powder bed of mesoporous silica (Syloid 244 FP) or synthetic dibasic calcium phosphate anhydrous (Fujicalin). The dosing accuracy a

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Singh, Saurabh, Bimlesh Kumar, Narendra Kumar Pandey, et al. "SYNTHESIS OF COPPER NANOPARTICLES USING ASCORBIC ACID AND CETYL TRIMETHYL AMMONIUM BROMIDE." Asian Journal of Pharmaceutical and Clinical Research 11, no. 14 (2018): 62. http://dx.doi.org/10.22159/ajpcr.2018.v11s2.28531.

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Objective: The present study highlights the development of a method to synthesize copper nanoparticles (CuNPs).Methods: CuNPs were developed using 0.01 M copper penta sulfate and 0.11 M of ascorbic acid (AA) and 0.03 M of cetyl trimethyl ammonium bromide solution. The synthesized CuNPs were differentiated through filtration and washed by water (deionized). CuNPs were kept in dialysis bag 70 KD in a 250 mL glass beaker along with distilled water. The assembly was kept on a magnetic stirrer for 24 h at 500 rpm. Then, the dialysis bag containing CuNPs solution was filtered by a filter assembly wi

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23

López, Eduardo, Temir A. Britayev, Daniel Martin, and Guillermo San Martín. "New symbiotic associations involving Syllidae (Annelida: Polychaeta), with taxonomic and biological remarks on Pionosyllis magnifica and Syllis cf. armillaris." Journal of the Marine Biological Association of the United Kingdom 81, no. 3 (2001): 399–409. http://dx.doi.org/10.1017/s0025315401004015.

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Several new symbiotic associations involving Syllidae (Annelida: Polychaeta) are reported. The number of known host sponge species infested by Haplosyllis spongicola is updated to 36, with seven hosts being reported for the first time (i.e. Aplysina corrugata, Aplysina sp., Cliona sp., Cliona viridis, Phorbas tenacior, one sponge from Iran, one sponge from Cambodia). Two infestation patterns (a few worms per host cm3 in temperate waters and 10s or 100s in tropical waters) are identified. The taxonomic and ecological characteristics of the species are discussed. Five associations occurring betw

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Klapiszewski, Łukasz, Karol Bula, Marta Sobczak, and Teofil Jesionowski. "Influence of Processing Conditions on the Thermal Stability and Mechanical Properties of PP/Silica-Lignin Composites." International Journal of Polymer Science 2016 (2016): 1–9. http://dx.doi.org/10.1155/2016/1627258.

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Functional silica-lignin dual fillers were obtained via mechanical grinding of the components (Syloid 244 silica and kraft lignin). Of particular importance here is the fact that lignin is a natural polymer and particularly that it is a waste by-product of paper production, whose recycling is highly desirable. The product underwent comprehensive dispersive-morphological and thermal analysis. SiO2-lignin hybrid fillers were also used in polypropylene-based composites, extruded via corotating a twin screw machine with different screw speeds. The thermogravimetric data obtained for the extrudates

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Gallo, Marta, Luca Serpella, Federica Leone, et al. "Piroxicam Loading onto Mesoporous Silicas by Supercritical CO2 Impregnation." Molecules 26, no. 9 (2021): 2500. http://dx.doi.org/10.3390/molecules26092500.

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Piroxicam (PRX) is a commonly prescribed nonsteroidal anti-inflammatory drug. Its efficacy, however, is partially limited by its low water solubility. In recent years, different studies have tackled this problem and have suggested delivering PRX through solid dispersions. All these strategies, however, involve the use of potentially harmful solvents for the loading procedure. Since piroxicam is soluble in supercritical CO2 (scCO2), the present study aims, for the first time, to adsorb PRX onto mesoporous silica using scCO2, which is known to be a safer and greener technique compared to the org

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Chaudhari, Smruti P., Mittal Bhadiyadra, and Rutesh H. Dave. "Evaluating the effect of the porous and non-porous colloidal silicon dioxide as a stabilizer on amorphous solid dispersion." Journal of Drug Delivery and Therapeutics 10, no. 5 (2020): 255–63. http://dx.doi.org/10.22270/jddt.v10i5.4323.

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Advancement in the discovery of drugs has led to many highly lipophilic compounds with very low water solubility. Amorphous solid dispersion is one of the emerging technologies to increase the solubility of these drugs. The stability of these systems is critical since the high energy system tends to recrystallize, which negates the benefits of these systems. In this paper, we are evaluating the use of colloidal silicon dioxide as a potential stabilizer to stabilize the amorphous solid dispersions. Two types of colloidal silicon dioxide are used: porous colloidal silicon dioxide -Syloid 244 Fp

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Hazemba, Kubota Mwaka, Jivan Jyoti, Sheetu Wadhwa, et al. "INFLUENCE OF FORMULATION PARAMETERS ON DISSOLUTION RATE ENHANCEMENT OF ACYCLOVIR USING LIQUISOLID FORMULATION." Asian Journal of Pharmaceutical and Clinical Research 11, no. 14 (2018): 36. http://dx.doi.org/10.22159/ajpcr.2018.v11s2.28537.

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Objective: The objective of this research work is to explore the use of liquisolid technique in enhancement of acyclovir dissolution rate. This current study was planned to assess the impact of different formulation variables, such as non-volatile liquid type and concentrations of acyclovir on its dissolution rates profile. Method: Acyclovir liquisolid tablets were prepared with Tween 60 (liquid vehicle), Microcrystalline cellulose PH 102 (acted as a carrier to turn liquid medication into free-flowing powder) and Syloid XDP (coating material). In vitro, drug dissolution rate of liquisolid form

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Kostelanská, Klára, Barbora Blahová Prudilová, Sylva Holešová, Jakub Vlček, David Vetchý, and Jan Gajdziok. "Comparative Study of Powder Carriers Physical and Structural Properties." Pharmaceutics 14, no. 4 (2022): 818. http://dx.doi.org/10.3390/pharmaceutics14040818.

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High specific surface area (SSA), porous structure, and suitable technological characteristics (flow, compressibility) predetermine powder carriers to be used in pharmaceutical technology, especially in the formulation of liquisolid systems (LSS) and solid self-emulsifying delivery systems (s-SEDDS). Besides widely used microcrystalline cellulose, other promising materials include magnesium aluminometasilicates, mesoporous silicates, and silica aerogels. Clay minerals with laminar or fibrous internal structures also provide suitable properties for liquid drug incorporation. This work aimed at

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Perez-Roman, Ines, Filip Kiekens, Damian Cordoba-Diaz, Juan Jose Garcia-Rodriguez, and Manuel Cordoba-Diaz. "Development of a Solid Formulation Containing a Microemulsion of a Novel Artemisia Extract with Nematocidal Activity for Oral Administration." Pharmaceutics 12, no. 9 (2020): 873. http://dx.doi.org/10.3390/pharmaceutics12090873.

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Background: Intestinal nematode infections are usually treated with benzimidazole drugs, but the emergence of resistance to these drugs has led to an increasing demand of new anthelmintic strategies. A new microemulsion formulation (ME) consisting of an Artemisia absinthium extract with proven nematocidal efficacy was previously developed. The aim of our study is to implement a D-optimal mixture design methodology to increase the amount of a silica material (loaded with this ME) in a tablet formulation, considering its tensile strength and disintegration time. Methods: 16 experiments or combin

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Zaghloul, Nada, Azza A. Mahmoud, Nermeen A. Elkasabgy, and Nada M. El Hoffy. "PLGA-modified Syloid^®-based microparticles for the ocular delivery of terconazole: in-vitro and in-vivo investigations." Drug Delivery 29, no. 1 (2022): 2117–29. http://dx.doi.org/10.1080/10717544.2022.2092239.

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López, Eduardo, and Ramón Gallego. "Temporal variation of a syllid (Syllidae: Polychaeta) taxocoenosis associated with Stypocaulon scoparium (Stypocaulaceae: Phaeophyceae) in the western Mediterranean." Journal of the Marine Biological Association of the United Kingdom 86, no. 1 (2006): 51–59. http://dx.doi.org/10.1017/s0025315406012859.

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Between May of 2000 and July of 2001 a study aiming to determine the seasonal variation of syllid local population abundances was carried out. Samples were taken every second month and consisted of two replicates, each one being a quadrat 20 cm wide. After fixing, the samples were washed and the draining water was passed through a 1 mm sieve; then the syllids were identified and counted. For each replicate a number of ecological indexes were calculated, namely population density, number of species and Shannon's and Simpson's diversity indexes, computing mean values for each sample. In order to

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Sherif, Abdelrahman Y., and Mohamed A. Ibrahim. "Unveiling the Superiority of Innovative Carbonated Self-Nanoemulsifying Drug Delivery Systems in Improving the Stability of Acid-Labile Drugs: Atorvastatin as a Model Drug." Processes 12, no. 6 (2024): 1169. http://dx.doi.org/10.3390/pr12061169.

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Atorvastatin (AT) is widely prescribed by physicians during the treatment of hyperlipidemia. The self-nanoemulsifying drug delivery system (SNEDDS) is used to overcome its low drug solubility and bioavailability. However, the presence of free fatty acids in SNEDDS formulation resulted in remarkable AT degradation. This study explores innovative carbonated SNEDDS to enhance the stability of AT within SNEDDS formulation. Various types of SNEDDS formulations were prepared and evaluated. In vitro dissolution was performed to examine the ability of SNEDDS formulation to enhance AT dissolution. The

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Rashid, Aisha, Muhammad Irfan, Yousaf Kamal, et al. "In Vitro and Biological Evaluation of Oral Fast-Disintegrating Films Containing Ranitidine HCl and Syloid® 244FP-Based Ternary Solid Dispersion of Flurbiprofen." Pharmaceutics 16, no. 2 (2024): 164. http://dx.doi.org/10.3390/pharmaceutics16020164.

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Flurbiprofen (FBP), a nonsteroidal anti-inflammatory drug (NSAID), is commonly used to treat the pain of rheumatoid arthritis, but in prolonged use it causes gastric irritation and ulcer. To avoid these adverse events of NSAIDs, the simultaneous administration of H2 receptor antagonists such as ranitidine hydrochloride (RHCl) is obligatory. Here, we developed composite oral fast-disintegrating films (ODFs) containing FBP along with RHCl to provide a gastroprotective effect as well as to enhance the solubility and bioavailability of FBP. The ternary solid dispersion (TSD) of FBP was fabricated

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Ertan Çinar, Melih. "Ecological features of Syllidae (Polychaeta) from shallow-water benthic environments of the Aegean Sea, eastern Mediterranean." Journal of the Marine Biological Association of the United Kingdom 83, no. 4 (2003): 737–45. http://dx.doi.org/10.1017/s0025315403007732h.

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Ecological features of Syllidae inhabiting shallow-water benthic habitats of the Aegean Sea were analysed by utilizing some univariate and multivariate statistical methods. A total of 121 benthic materials collected in a variety of substrata and depths (0–76 m) contained 90 syllid species belonging to the four subfamilies Autolytinae, Exogoninae, Eusyllinae and Syllinae. Among the subfamilies, Syllinae were characterized by a high number of species and Exogoninae by a high number of individuals. Although dominant species varied according to substrata, the two species, Grubeosyllis clavata and

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Teaima, Mahmoud, Sandra Hababeh, Mai Khanfar, Fares Alanazi, Doaa Alshora, and Mohammed El-Nabrawi. "Design and Optimization of Pioglitazone Hydrochloride Self-Nanoemulsifying Drug Delivery System (SNEDDS) Incorporated into an Orally Disintegrating Tablet." Pharmaceutics 14, no. 2 (2022): 425. http://dx.doi.org/10.3390/pharmaceutics14020425.

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Pioglitazone Hydrochloride (PGZ) suffers from poor aqueous solubility. The aim of this research was to design orally disintegrating tablets with self-nanoemulsifying properties (T-SNEDDS) to improve the Pioglitazone solubility and dissolution rate. Three liquid self-nanoemulsifying systems (L-SNEDDS) were formulated and evaluated for transmittance percentage, emulsification time, particle size, Poly dispersity index (PDI), percentage of content, solubility and stability. The optimum L-SNEDDS formula was converted to a solidified self-nanoemulsifying drug delivery system (S-SNEDDS) by adsorptio

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Álvarez, Patricia, and Guillermo San Martín. "A new species of Sphaerosyllis (Annelida: Polychaeta: Syllidae) from Cuba, with a list of syllids from the Guanahacabibes Biosphere Reserve (Cuba)." Journal of the Marine Biological Association of the United Kingdom 89, no. 7 (2009): 1427–35. http://dx.doi.org/10.1017/s0025315409000654.

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Sphaerosyllis sandrae sp. nov. (Annelida: Polychaeta: Syllidae) is described as a new species from shallow sandy bottoms off Guanahacabibes Biosphere Reserve (Cuba). Thirteen more syllid species belonging to nine genera (Exogone, Myrianida, Opisthosyllis, Parexogone, Plakosyllis, Salvatoria, Syllides, Sphaerosyllis and Syllis) have been found from algal and sand bottom samples from the same area; four species that belong to the genera Myrianida, Syllides and Parexogone are only identified at the generic level.

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Malanchuk, N. V., M. B. Demchuk та T. A. Hroshovyi. "ВИВЧЕННЯ ВПЛИВУ ДОПОМІЖНИХ РЕЧОВИН НА ФАРМАКО-ТЕХНОЛОГІЧНІ ПОКАЗНИКИ ТАБЛЕТОК НА ОСНОВІ БІСОПРОЛОЛУ ФУМАРАТУ З ІНДАПАМІДОМ". Фармацевтичний часопис, № 4 (30 листопада 2023): 12–21. http://dx.doi.org/10.11603/2312-0967.2023.4.14368.

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Мета роботи. Вивчення впливу допоміжних речовин на фармако-технологічні показники маси для таблетування та таблеток бісопрололу фумарату з індапамідом. Матеріали і методи. Для фармацевтичної розробки таблеток були обрані субстанції бісопрололу фумарату та індапаміду; 27 допоміжних речовин із груп розпушувачів, ковзних речовин, змащуючих речовин, наповнювачів на основі мікрокристалічної целюлози та багатофункціональних наповнювачів. Для вивчення впливу ДР використовували п’ятифакторний експеримент на підставі греко-латинського кубу другого порядку. Таблетки отримували методом прямо

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ÇINAR, MELIH ERTAN. "Syllis ergeni: a new species of Syllidae (Annelida: Polychaeta) from Izmir Bay (Aegean Sea, eastern Mediterranean Sea)." Zootaxa 1036, no. 1 (2005): 43. http://dx.doi.org/10.11646/zootaxa.1036.1.4.

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The faunal analysis of hard bottom materials collected from Alsancak Harbour and its vicinity (Izmir Bay, Aegean Sea) revealed a new syllid species, Syllis ergeni. The species is mainly characterized by having a dark-brown colour pattern on the dorsum of anterior and middle segments, short blade falcigers, the number and morphology of aciculae, and a pigmented proventriculus and pharynx. The morphology, ecology, distribution and reproductive features of the species are explained and discussed.

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Tayal, Shivam, and Md Mannan Ansari. "Formulation and Evaluation of Self Nano Emulsifying Drug Delivery System Containing Mesalamine." Asian Journal of Applied Science and Technology 09, no. 02 (2025): 86–99. https://doi.org/10.38177/ajast.2025.9209.

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The Self-Nano Emulsifying Drug Delivery System (SNEDDS) represents a modern strategy to improving the oral availability of poorly water-soluble medication. The two main goals of the study were to design and evaluate mesalamine containing S-SNEDDS that would deliver the medicine particularly to the colon, increasing its oral bioavailability, and to investigate the characteristics of biosurfactants as pharmaceutical emulsifiers for L-SNEDDS. The optimal formulations were determined using a pseudo-ternary phase diagram comprising olive oil as the oil phase, biosurfactant as the surfactant, and PE

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AGUADO, M. TERESA, GUILLERMO SAN MARTÍN, and HARRY A. TEN HOVE. "Syllidae (Annelida: Polychaeta) from Indonesia collected by the Siboga (1899-1900) and Snellius II (1984) expeditions." Zootaxa 1673, no. 1 (2008): 1. http://dx.doi.org/10.11646/zootaxa.1673.1.1.

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Twenty seven samples of syllids (Annelida: Polychaeta) from Indonesia collected during the Siboga Expedition (1899– 1900) and five during the Snellius II Expedition (1984) have been examined. Material from several other museums and Institutions has also been included. Unpublished identifications of Siboga material by Augener have been checked and all specimens have been named according to current taxonomic knowledge. A total of 30 taxa have been identified, belonging to 10 different genera: Branchiosyllis, Haplosyllides, Eusyllis, Odontosyllis, Opisthosyllis, Paraehlersia, Pionosyllis, Sphaero

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Álvarez-Campos, Patricia, João Gil, and Guillermo San Martín. "Unveiling the Rosetta Stone of syllids: redescription and neotype designation of Syllis monilaris Savigny in Lamarck, 1818, type species of type genus of family Syllidae Grube, 1850 (Annelida)." Zootaxa 4040, no. 3 (2015): 317–30. https://doi.org/10.11646/zootaxa.4040.3.4.

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Álvarez-Campos, Patricia, Gil, João, Martín, Guillermo San (2015): Unveiling the Rosetta Stone of syllids: redescription and neotype designation of Syllis monilaris Savigny in Lamarck, 1818, type species of type genus of family Syllidae Grube, 1850 (Annelida). Zootaxa 4040 (3): 317-330, DOI: 10.11646/zootaxa.4040.3.4

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Smruti, P. Chaudhari, and Gupte Anshul. "Mesoporous Silica as a Carrier for Amorphous Solid Dispersion." British Journal of Pharmaceutical Research 16, no. 6 (2017): 1–19. https://doi.org/10.9734/BJPR/2017/33553.

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In the past decade, the discovery of active pharmaceutical substances with high therapeutic value but poor aqueous solubility has increased, thus making it challenging to formulate these compounds as oral dosage forms. The bioavailability of these drugs can be increased by formulating these drugs as an amorphous drug delivery system. Use of porous media like mesoporous silica has been investigated as a potential means to increase the solubility of poorly soluble drugs and to stabilize the amorphous drug delivery system. These materials have nanosized capillaries and the large surface area whic

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LANGENECK, JOACHIM, LUIGI MUSCO, GIULIO BUSONI, ILARIA CONESE, STEFANO ALIANI, and ALBERTO CASTELLI. "Syllidae (Annelida: Phyllodocida) from the deep Mediterranean Sea, with the description of three new species." Zootaxa 4369, no. 2 (2018): 197. http://dx.doi.org/10.11646/zootaxa.4369.2.3.

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Despite almost two centuries of research, the diversity of Mediterranean deep-sea environments remain still largely unexplored. This is particularly true for the polychaete family Syllidae. We report herein 14 species; among them, we describe Erinaceusyllis barbarae n. sp., Exogone sophiae n. sp. and Prosphaerosyllis danovaroi n. sp. and report Parexogone wolfi San Martín, 1991, Exogone lopezi San Martín, Ceberio & Aguirrezabalaga, 1996 and Anguillosyllis Day, 1963 for the first time from the Western Mediterranean, the latter based on a single individual likely belonging to an undescribed

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Pernet, Bruno. "Benthic Egg Masses and Larval Development of Amblyosyllis Speciosa (Polychaeta: Syllidae)." Journal of the Marine Biological Association of the United Kingdom 78, no. 4 (1998): 1369–72. http://dx.doi.org/10.1017/s0025315400044568.

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Eggs of the syllid polychaete Atnblyosyllis speciosa are deposited in benthic gelatinous masses. Embryos and larvae develop within these masses until about three weeks after fertilization, after which they crawl or swim away and metamorphose. Only one other syllid, the Mediterranean Syllides edentula, has been reported to form benthic egg masses.While some syllid polychaetes spawn gametes freely into the water column where they are fertilized and develop without additional parental care, most species protect developing embryos in some fashion. Four modes of brood protection have been reported

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SPRINGER, CHRIS, DAISUKE S. SATO, KOHEI OGUCHI, NAOTO JIMI, TORU MIURA, and M. TERESA AGUADO. "Two new species of Syllidae (Annelida) from Misaki Bay and Sugashima Island, Japan." Zootaxa 5632, no. 1 (2025): 51–83. https://doi.org/10.11646/zootaxa.5632.1.3.

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The shorelines of Japan host diverse ecosystems, particularly in the shallow coastal waters, which are rich in syllid species. This study describes two new Syllidae species: Virchowia christophi sp. nov., discovered at Misaki and Sugashima Island, and Paraopisthosyllis rufa sp. nov., found at Misaki. Additionally, we provide a redescription of Syllis okadai Fauvel, 1913, based on specimens collected from Misaki. Virchowia christophi sp. nov. shows a unique combination of characters, such as branched nuchal epaulettes together with a complex colouration pattern featuring white, beige, and brown

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Hijazi, Rola A., and Fatme M. Charaf. "Finite Groups with Certain Permutability Criteria." European Journal of Pure and Applied Mathematics 12, no. 2 (2019): 571–76. http://dx.doi.org/10.29020/nybg.ejpam.v12i2.3399.

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Let G be a finite group. A subgroup H of G is said to be S-permutable in G if itpermutes with all Sylow subgroups of G. In this note we prove that if P, the Sylowp-subgroup of G (p > 2), has a subgroup D such that 1 <|D|<|P| and all subgroups H of P with |H| = |D| are S-permutable in G, then G′ is p-nilpotent.

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ZHANG, ZHENXIANG, and RUIRUI XIE. "SYLOW p-PSEUDOPRIMES TO SEVERAL BASES FOR SEVERAL PRIMES p." Bulletin of the Australian Mathematical Society 81, no. 1 (2009): 165–76. http://dx.doi.org/10.1017/s0004972709000744.

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AbstractBrowkin [‘Some new kinds of pseudoprimes’, Math. Comp. 73 (2004), 1031–1037] gave examples of strong pseudoprimes to many bases which are not Sylow p-pseudoprimes to two bases only, where p=2 or 3. In contrast to Browkin’s examples, Zhang [‘Notes on some new kinds of pseudoprimes’, Math. Comp. 75 (2006), 451–460] gave facts and examples which are unfavorable for Browkin’s observation on detecting compositeness of odd composite numbers. In particular, Zhang gave a Sylowp-pseudoprime (with 27 decimal digits) to the first 6 prime bases for all the first 6 primes p, and conjectured that fo

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Soto, Eulogio H., and Guillermo San Martín. "New reports and a new species of Syllidae (Annelida) from Chilean Patagonia." Journal of the Marine Biological Association of the United Kingdom 98, no. 7 (2017): 1599–607. http://dx.doi.org/10.1017/s0025315417001242.

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The Syllidae subfamilies Eusyllinae, Anoplosyllinae and Autolytinae, as well as the incertae sedis genera (Aguado et al., 2012), were studied from samples collected in shallow water from fjords and channels in Chilean Patagonia. One new species Paraehlersia kawesqar sp. nov. is described. The genus Nudisyllis Knox & Cameron, 1970 is recorded for the first time for Chile, while the species Brachysyllis infuscata (Ehlers, 1901a) and Syllides japonica Imajima, 1966 are recorded for the first time for continental Chile. Finally, Syllides articulosa Ehlers, 1897 and Epigamia sp. are also report

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Nogueira Júnior, Miodeli, and Verônica Maria de Oliveira. "Strategies of plankton occupation by polychaete assemblages in a subtropical estuary (south Brazil)." Journal of the Marine Biological Association of the United Kingdom 97, no. 8 (2016): 1651–61. http://dx.doi.org/10.1017/s0025315416001120.

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Polychaete abundance and assemblage structure were analysed from 144 zooplankton samples taken in eight seasonal campaigns between October 2007 and November 2008 on Babitonga Bay estuary (south Brazil). A total of 16 taxa were found, classified in three categories: (i) larvae (five taxa) dominated byLoimiasp. (Terebellidae) (up to 59 ind 100 m−3); (ii) syllid epitokes (three taxa) dominated byProcerasteasp.2 (up to 11 ind 100 m−3) andMyrianidasp. (up to 6 ind 100 m−3); and (iii) adults of typically benthic species (eight taxa) which were only occasionally sampled in low densities (<1 ind 10

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JORDANO, PEDRO. "Frugivory, external morphology and digestive system in mediterranean sylviid warblers Sylvia spp." Ibis 129 (April 3, 2008): 175–89. http://dx.doi.org/10.1111/j.1474-919x.1987.tb03199.x.

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