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Journal articles on the topic 'Sympathomimetic amines'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Wall, Ellen L., Jerome A. Leow, Jonathan Ho, and Yun T. Hwang. "106 Haemorrhagic spinal cord infarct – a rare complication of sympathomimetic amine toxicity." Journal of Neurology, Neurosurgery & Psychiatry 90, e7 (2019): A34.3—A35. http://dx.doi.org/10.1136/jnnp-2019-anzan.94.

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IntroductionSympathomimetic amines are recreational substances, available illegally as amphetamine derivatives (eg, ‘ecstasy’ and ‘speed’). Ingestion can lead to significant medical complications such as hyperthermia, tachyarrhythmia, seizures and strokes, attributed to catecholamine surge and sympathetic overstimulation.MethodWe report an unusual case of sympathomimetic amine ingestion manifesting as hypertension followed by acute onset flaccid paralysis of lower limbs bilaterally and T11 level anaesthesia in a 64 year old woman secondary to haemorrhagic cord infarct.ResultsAn MRI spine showe

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2

Costa, Vera Marisa, Luciana Grazziotin Rossato Grando, Elisa Milandri, et al. "Natural Sympathomimetic Drugs: From Pharmacology to Toxicology." Biomolecules 12, no. 12 (2022): 1793. http://dx.doi.org/10.3390/biom12121793.

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Sympathomimetic agents are a group of chemical compounds that are able to activate the sympathetic nervous system either directly via adrenergic receptors or indirectly by increasing endogenous catecholamine levels or mimicking their intracellular signaling pathways. Compounds from this group, both used therapeutically or abused, comprise endogenous catecholamines (such as adrenaline and noradrenaline), synthetic amines (e.g., isoproterenol and dobutamine), trace amines (e.g., tyramine, tryptamine, histamine and octopamine), illicit drugs (e.g., ephedrine, cathinone, and cocaine), or even caff

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3

Sato, N., Y. T. Shen, K. Kiuchi, R. P. Shannon, and S. F. Vatner. "Splenic contraction-induced increases in arterial O2 reduce requirement for CBF in conscious dogs." American Journal of Physiology-Heart and Circulatory Physiology 269, no. 2 (1995): H491—H503. http://dx.doi.org/10.1152/ajpheart.1995.269.2.h491.

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We investigated the extent to which sympathomimetic amines induced splenic contraction and associated increases in arterial O2 content (CaO2) and how these mechanisms affected control of the coronary circulation by sympathomimetic amines in conscious dogs. Blood hemoglobin (Hb) and CaO2 increased by 16 +/- 2 and 18 +/- 2%, respectively, during norepinephrine (NE, 0.8 micrograms.kg-1.min-1 iv) in the intact, conscious state after splenic contraction. Phenylephrine (PE) induced similar effects. After either alpha 1-adrenergic-receptor blockade or splenectomy, these effects were abolished. Isopro

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4

Oppenheimer, E., E. Akavia, S. Shavit, and A. D. Korczyn. "Sympathomimetic amines and cardiac arrhythmias." Cardiovascular Research 24, no. 9 (1990): 754–57. http://dx.doi.org/10.1093/cvr/24.9.754.

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5

Salem, Fatma Basyoni, and Mohamed Ibrahim Walash. "Spectrophotometric determination of certain sympathomimetic amines." Analyst 110, no. 9 (1985): 1125. http://dx.doi.org/10.1039/an9851001125.

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6

Russo, Elena, Francesco Giombi, Giovanni Paoletti, et al. "Use, Abuse, and Misuse of Nasal Medications: Real-Life Survey on Community Pharmacist’s Perceptions." Journal of Personalized Medicine 13, no. 4 (2023): 579. http://dx.doi.org/10.3390/jpm13040579.

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Background: Medication overuse is an increasing global problem, especially for those rhinology diseases whose management requires over-the-counter drugs. This observational community pharmacy-based study aimed to investigate the actual use of the best-selling topical nasal medications and to characterize the clinical issues underlying their query through the pharmacist’s perception. Methods: In the pilot phase, a preliminary survey was developed by a team of researchers and tested on a small sample of practitioners to assess usability and intelligibility. Eventual amendments were made accordin

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7

Fjalland, B. "Sympathomimetic Amines and Gastric Secretion in Rats." Acta Pharmacologica et Toxicologica 35, no. 4 (2009): 293–99. http://dx.doi.org/10.1111/j.1600-0773.1974.tb00749.x.

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8

Waller, Derek G., and Colin E. Robertson. "Role of sympathomimetic amines during cardiopulmonary resuscitation." Resuscitation 22, no. 2 (1991): 181–90. http://dx.doi.org/10.1016/0300-9572(91)90010-v.

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9

Broadley, Kenneth J., M. Akhtar Anwar, Amy A. Herbert, et al. "Effects of dietary amines on the gut and its vasculature." British Journal of Nutrition 101, no. 11 (2008): 1645–52. http://dx.doi.org/10.1017/s0007114508123431.

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Trace amines, including tyramine and β-phenylethylamine (β-PEA), are constituents of many foods including chocolate, cheeses and wines and are generated by so-called ‘friendly’ bacteria such as Lactobacillus, Lactococcus and Enterococcus species, which are found in probiotics. We therefore examined whether these dietary amines could exert pharmacological effects on the gut and its vasculature. In the present study we examined the effects of tyramine and β-PEA on the contractile activity of guinea-pig and rat ileum and upon the isolated mesenteric vasculature and other blood vessels. Traditiona

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10

Armbruster, D. A., E. C. Hubster, M. S. Kaufman, and M. K. Ramon. "Cloned enzyme donor immunoassay (CEDIA) for drugs-of-abuse screening." Clinical Chemistry 41, no. 1 (1995): 92–98. http://dx.doi.org/10.1093/clinchem/41.1.92.

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Abstract Large numbers of specimens (5000-18,000) were screened for amphetamines, barbiturates, cocaine, marijuana, opiates, and phencyclidine by RIA (Roche), Emit II (Syva), and a new immunoassay, CEDIA (cloned enzyme donor immunoassay, Microgenics). All immunoassays performed equivalently for cocaine, opiates, and phencyclidine. All immunoassays detected the same amphetamine/methamphetamine-positive specimens, but all also detected numerous specimens containing cross-reacting sympathomimetic amines. CEDIA detected 100%, Emit II 93%, and RIA 82% of the barbiturate-positive specimens. Emit II

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11

Trendelenburg, U., A. Langeloh, and H. Bönisch. "Mechanism of Action of Indirectly Acting Sympathomimetic Amines." Journal of Vascular Research 24, no. 5 (1987): 261–70. http://dx.doi.org/10.1159/000158702.

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12

Walash, Mohamed I., Abed Abou Ouf, and Fatma B. Salem. "Colorimetric Determination of Sympathomimetic Amines Methyldopa and Noradrenaline." Journal of AOAC INTERNATIONAL 68, no. 1 (1985): 91–95. http://dx.doi.org/10.1093/jaoac/68.1.91.

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Abstract The chromogenic reagent p-dimethylaminocinnamaldehyde (PDAC) is introduced for the determination of the sympathomimetic amines methyldopa and noradrenaline. The method is based on measurement of the orange color developed when the alkaline solution of methyldopa and noradrenaline is allowed to react with PDAC at pH 5.0. The color developed obeys Beer's law in the concentration range 0.1-1.5 mL of 2 x 103M solution of noradrenaline and methyldopa. The results are compared with those obtained with another chromogenic reagent, pdimethylaminobenzaldehyde (PDAB). Determinations on dosage f

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13

Caldwell, R. "Systemic delivery of sympathomimetic amines by transdermal iontophoresis." International Journal of Pharmaceutics 123, no. 2 (1995): 181–85. http://dx.doi.org/10.1016/0378-5173(95)00049-o.

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14

Callingham, B. A. "Some Aspects of the Enzymic Inactivation of Sympathomimetic Amines." Journal of Vascular Research 24, no. 5 (1987): 240–52. http://dx.doi.org/10.1159/000158700.

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15

Check, D., J. H. Check, and E. Dix. "Correction of Normoprolactinemic Galactorrhea Following Treatment With Sympathomimetic Amines." Fertility and Sterility 89, no. 4 (2008): S15. http://dx.doi.org/10.1016/j.fertnstert.2008.02.046.

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16

Van Dort, Marcian E., David L. Gildersleeve, and Donald M. Wieland. "Synthesis of 3H-labeled sympathomimetic amines for neuronal mapping." Journal of Labelled Compounds and Radiopharmaceuticals 28, no. 7 (1990): 831–40. http://dx.doi.org/10.1002/jlcr.2580280713.

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17

Check, J. H., and M. P. Dougherty. "Use of sympathomimetic amines to correct premenstrual urticaria and anaphylaxis." Clinical and Experimental Obstetrics & Gynecology 46, no. 2 (2019): 309–12. http://dx.doi.org/10.12891/ceog4727.2019.

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18

Check, Jerome, Jasmine Aly, Diane Check, Rachael Cohen, and Harriet Kaplan. "Abstract #1161: Idiopathic Hypokalemic Paralysis Successfully Treated with Sympathomimetic Amines." Endocrine Practice 22 (May 2016): 281–82. http://dx.doi.org/10.1016/s1530-891x(20)44807-4.

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19

Joos, Thad H. "PREVENTIVE THERAPY FOR ASTHMA IN CHILDREN: A 9-YEAR EXPERIENCE IN EASTERN FINLAND." Pediatrics 98, no. 2 (1996): 334. http://dx.doi.org/10.1542/peds.98.2.334b.

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Purpose of the Study. The investigation was carried out to ascertain if the treatment of childhood asthma in Finland changed after the publication of consensus guidelines in 1989 in Europe. Methods. In a well-defined geographic area of Finland with about 53 000 children under 15 years of age, the asthma care for most youngsters was given through a regional allergy center headed by a pediatric allergist. Patient records were reviewed every other year from 1985 to 1993 regarding methods of treatment such as the use of long-term preventative agents, theophylline, and sympathomimetics amines. Resu

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20

Feria, M., C. Alvarez, J. Domínguez, A. Sánchez, and J. Boada. "Naloxone potentiation of cardiovascular responses to sympathomimetic amines in the rat." Journal of Pharmacology and Experimental Therapeutics 255, no. 2 (1990): 523–28. https://doi.org/10.1016/s0022-3565(25)22978-0.

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21

Knoll, Joseph, Ildikó Miklya, Berta Knoll, Raissa Markó, and Daniel Rácz. "Phenylethylamine and tyramine are mixed-acting sympathomimetic amines in the brain." Life Sciences 58, no. 23 (1996): 2101–14. http://dx.doi.org/10.1016/0024-3205(96)00204-4.

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22

Catlin, D. H., R. C. Kammerer, C. K. Hatton, M. H. Sekera, and J. L. Merdink. "Analytical chemistry at the Games of the XXIIIrd Olympiad in Los Angeles, 1984." Clinical Chemistry 33, no. 2 (1987): 319–27. http://dx.doi.org/10.1093/clinchem/33.2.319.

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Abstract The equipment, methods, logistics, and results of doping-control analyses for the 1984 Los Angeles Olympic Games are discussed in this article. Within 15 days, 1510 different urine specimens underwent 9440 screening analyses by a combination of gas chromatography, gas chromatography-mass spectrometry, "high-performance" liquid chromatography, and radioimmunoassay. These tests covered more than 200 different drugs and metabolites, including psychomotor stimulants, sympathomimetic amines, central nervous system stimulants, narcotic analgesics, and anabolic steroids. The results are summ

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23

Miller, Virginia M., Gilbert Marcelon, and Paul M. Vanhoutte. "Progesterone Augments the Venoconstrictor Effect of Ruscus without Altering Adrenergic Reactivity." Phlebology: The Journal of Venous Disease 6, no. 4 (1991): 261–68. http://dx.doi.org/10.1177/026835559100600410.

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Chronic administration of oestrogen and/or progesterone does not affect adrenergic neurotransmission or contractions initiated by sympathomimetic amines in the cutaneous venous smooth muscle of the dog. However, contractions initiated by the venotropic Ruscus-extract are enhanced following chronic exposure to progesterone, an affect that can be reversed by oestrogen. The contractions are mediated by an adrenergic and non-adrenergic component. The adrenergic component is enhanced by progesterone and decreased by oestrogen; the non-adrenergic component is most prominent when the serum-levels of

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24

Check, Jerome, Jasmine Aly, and Rachael Cohen. "Abstract #1022: Premenstrual Severe Labial Swelling and Pain Relieved with Sympathomimetic Amines." Endocrine Practice 22 (May 2016): 239–40. http://dx.doi.org/10.1016/s1530-891x(20)44720-2.

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25

CHECK, J. "Sympathomimetic amines as a novel treatment for refractory chronic idiopathic urticaria*1." Journal of Allergy and Clinical Immunology 113, no. 2 (2004): S135. http://dx.doi.org/10.1016/j.jaci.2003.12.482.

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26

Sastroasmoro, Sudigdo. "Recent Advances in Childhood Asthma." Paediatrica Indonesiana 20, no. 11-12 (2021): 236–87. http://dx.doi.org/10.14238/pi20.11-12.1980.236-87.

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Research in bronchial asthma shows striking advances in the last fifteen years. In recent years, advances in immunology and the introduction of beta adrenergic theory (neuro-humoral theory) lead to a new and comprehensive understanding on the pathogenesis and pathophysiology of asthma. Physiological changes in asthma are particularly concerning the affection of smaller air ways, the goal of the newer methods is to find the most sensitive and reliable method to detect small airway alteration. The current advances in the treatment of asthma are the sympathomimetic amines and th

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27

Elliott, J. "Current theories on the pathophysiology of equine laminitis – the link between the gut and foot." Proceedings of the British Society of Animal Science 2009 (April 2009): 243. http://dx.doi.org/10.1017/s1752756200030829.

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Equine laminitis is a painful debilitating condition that seems to be a product of domestication of horses associated with the practice of feeding carbohydrate rich pasture in excess of requirements, particularly in ponies. We have been working on the hypothesis that caecal bacteria, when presented with carbohydrate in large quantities tend to ferment this. Fermentation by gram positive bacteria is associated with a fall in pH of the caecal liquor. As a means of providing themselves with increased intracellular buffering capacity, these bacteria produce amino acid decarboxylase enzymes which c

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28

Check, J. H., and B. Katsoff. "Transient sixth cranial nerve palsy following orgasm abrogated by treatment with sympathomimetic amines." Clinical and Experimental Obstetrics & Gynecology 41, no. 4 (2014): 468–70. http://dx.doi.org/10.12891/ceog17772014.

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29

Moawad, Michael, Cheang S. Khoo, Samiuela Lee, and James R. Hennell. "Simultaneous Determination of Eight Sympathomimetic Amines in Urine by Gas Chromatography/Mass Spectrometry." Journal of AOAC INTERNATIONAL 93, no. 1 (2010): 116–22. http://dx.doi.org/10.1093/jaoac/93.1.116.

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Abstract A GC method was developed for the identification and quantitation of eight sympathomimetic amines in urine, i.e., amphetamine, methamphetamine, mephentermine, ephedrine, pseudoephedrine, methylenedioxyamphetamine, methylenedioxymethamphetamine, and methylenedioxyethylamphetamine. Methoxyphenamine was used as the internal standard (IS). The assay is rapid, sensitive, and simple to perform. It involves a liquidliquid extraction procedure with simultaneous in-solution derivatization of the organic layer with pentafluorobenzoyl chloride (PFB-Cl), followed by GC/MS analysis. These derivati

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30

Ross, S. B., and A. L. Renyi. "Uptake of Some Tritiated Sympathomimetic Amines by Mouse Brain Cortex Slices In Vitro." Acta Pharmacologica et Toxicologica 24, no. 4 (2009): 297–309. http://dx.doi.org/10.1111/j.1600-0773.1966.tb00392.x.

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31

Marvola, Martti. "Metabolic Actions of some Sympathomimetic Amines and their Acetyl Derivatives in the Rabbit." Acta Pharmacologica et Toxicologica 40, no. 1 (2009): 22–32. http://dx.doi.org/10.1111/j.1600-0773.1977.tb02050.x.

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32

Dougherty, Michael, Benjamin Jaffe, and Jerome Check. "Abstract #919: The Use of Sympathomimetic Amines to Eradicate Premenstrual Urticaria and Anaphylaxis." Endocrine Practice 21 (May 2015): 187–88. http://dx.doi.org/10.1016/s1530-891x(20)42799-5.

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33

Elliott, P., S. J. Marsh, and D. A. Brown. "Inhibition of Ca-spikes in rat preganglionic cervical sympathetic nerves by sympathomimetic amines." British Journal of Pharmacology 96, no. 1 (1989): 65–76. http://dx.doi.org/10.1111/j.1476-5381.1989.tb11785.x.

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34

Akavia, E., S. Shavit, E. Openheimer, and A. D. Korczyn. "Arrhythmogenic effects of catechol- and sympathomimetic amines. Involvement of alpha and beta adrenoceptors." European Journal of Pharmacology 183, no. 4 (1990): 1229–30. http://dx.doi.org/10.1016/0014-2999(90)94328-u.

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35

KURODA, Naotaka, Daisuke SATO, Kaname OHYAMA, Mitsuhiro WADA, Yuji NAKAHARA, and Kenichiro NAKASHIMA. "Separation of Sympathomimetic Amines of Abuse and Related Compounds by Micellar Electrokinetic Chromatography." CHEMICAL & PHARMACEUTICAL BULLETIN 49, no. 7 (2001): 905–8. http://dx.doi.org/10.1248/cpb.49.905.

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36

Bende, M., and S. Löth. "Vascular effects of topical oxymetazoline on human nasal mucosa." Journal of Laryngology & Otology 100, no. 3 (1986): 285–88. http://dx.doi.org/10.1017/s0022215100099151.

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AbstractOxymetazoline, a derivative of imidazoline, is a widely used nasal decongestant. In contrast to other topical decongestants related to phenylephrine, sympathomimetic amines, it also induced a reduced nasal mucosal blood flow. The purpose of the present investigation was to evaluate the duration of effect of oxymetazoline on nasal airway resistance and mucosal blood flow. During the eight hours of study, the blood flow was reduced by 30–40 per cent in six hours. A similar decongestant effect of about 30 per cent was found during the same interval. The pharmacological profile of oxymetaz

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37

Haffner, J. F. W., B. I. Nesheim, and J. Setekleiv. "Potassium-Efflux and the Contractile Response to Sympathomimetic Amines in Circular Rabbit Fundus Muscle." Acta Pharmacologica et Toxicologica 31, no. 5-7 (2009): 412–20. http://dx.doi.org/10.1111/j.1600-0773.1972.tb03604.x.

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38

B�nisch, H. "The role of co-transported sodium in the effect of indirectly acting sympathomimetic amines." Naunyn-Schmiedeberg's Archives of Pharmacology 332, no. 2 (1986): 135–41. http://dx.doi.org/10.1007/bf00511403.

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39

Thurman, E. M., M. J. Pedersen, R. L. Stout, and T. Martin. "Distinguishing Sympathomimetic Amines from Amphetamine and Methamphetamine in Urine by Gas Chromatography/Mass Spectrometry." Journal of Analytical Toxicology 16, no. 1 (1992): 19–27. http://dx.doi.org/10.1093/jat/16.1.19.

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40

Mandrekas, Apostolos D. "Tragaras, S., et al. Extensive ischemic skin gangrene after use of sympathomimetic amines. (Greek)." Plastic and Reconstructive Surgery 91, Supplement (1993): 973. http://dx.doi.org/10.1097/00006534-199304001-00074.

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41

Weidner, J., and J. H. Check. "Marked improvement of the autoimmune syndrome associated with autoimmune hepatitis by treatment with sympathomimetic amines." Clinical and Experimental Obstetrics & Gynecology 41, no. 4 (2014): 460–61. http://dx.doi.org/10.12891/ceog17752014.

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42

Vatner, D. E., M. Lavallee, J. Amano, A. Finizola, C. J. Homcy, and S. F. Vatner. "Mechanisms of supersensitivity to sympathomimetic amines in the chronically denervated heart of the conscious dog." Circulation Research 57, no. 1 (1985): 55–64. http://dx.doi.org/10.1161/01.res.57.1.55.

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43

Ross, Svante B., and Diana Kelder. "Evoked Efflux of 3H-Bretylium by Sympathomimetic Amines from the Rat Vas Deferens in Vitro." Acta Pharmacologica et Toxicologica 40, no. 1 (2009): 87–96. http://dx.doi.org/10.1111/j.1600-0773.1977.tb02056.x.

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44

Friström, Sinikka, Martti Marvola, Erik Klinge, and Jaakko Halmekoski. "Effect of Acetyl Derivatives of some Sympathomimetic Amines on the Blood Pressure of the Rat." Acta Pharmacologica et Toxicologica 40, no. 2 (2009): 247–58. http://dx.doi.org/10.1111/j.1600-0773.1977.tb02075.x.

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45

Fabinyi-Szebehely, M., and J. Szebehely. "The Influence of Diphenhydramine on the Action of Sympathomimetic Amines.: I. Effect on Blood Pressure." Acta Pharmacologica et Toxicologica 8, no. 4 (2009): 343–48. http://dx.doi.org/10.1111/j.1600-0773.1952.tb02912.x.

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46

Miroshnichenko, N. A., and A. Yu Ovchinnikov. "Topical decongestants: myth and reality." Medical Council, no. 12 (July 29, 2018): 40–43. http://dx.doi.org/10.21518/2079-701x-2018-12-40-43.

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Nasal breathing plays an important role in the respiratory function, which ensures that a person consumes appropriate levels of air. Nasal obstruction causes a person to consume air mainly through the mouth, which impairs the numerous functions of the nose. This leads first to functional abnormalities, and then to morphological and structural changes. Topical decongestants that have the strongest and fastest effect are the most popular drugs to manage rapidly nasal obstruction. The main nasal decongestants can be divided into two groups: sympathomimetic amines: primary aliphatic, phenolic and

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47

Check, Jerome, Rachael Cohen, Diane Check, Harriet Kaplan, and Jasmine Aly. "Abstract #1024: Marked Improvement of Dermatitis Herpetiformis Associated with Pelvic Pain Following Treatment with Sympathomimetic Amines." Endocrine Practice 22 (May 2016): 241. http://dx.doi.org/10.1016/s1530-891x(20)44722-6.

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48

Derelanko, Michael J. "Gastric mucosal protection with ?-phenylethylamine (PEA) and other sympathomimetic amines against absolute ethanol in the rat." Digestive Diseases and Sciences 35, no. 6 (1990): 769–73. http://dx.doi.org/10.1007/bf01540182.

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49

Check, Jerome H., Brittney Katsoff та Rachael Cohen. "Novel Highly Effective Medical Treatment of Severe Treatment Refractory Crohnʼs Disease Using Sympathomimetic Amines: Case Report". Inflammatory Bowel Diseases 16, № 12 (2010): 1999–2000. http://dx.doi.org/10.1002/ibd.21269.

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50

Yasmin, L., K. Abdul Ameer Bassam, Jasim Mohamad Ban, and Kathum Omra Faiza. "The impact of Sudafed on spleen of albino mice." Medicni perspektivi 29, no. 4 (2024): 66–73. https://doi.org/10.26641/2307-0404.2024.4.319190.

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Pseudoephedrine (PSE), often known as Sudafed, belongs to a class of medications known as sympathomimetic amines, which affect the digestive system, respiratory system, and cardiovascular system. This drug has a long history of medical use; it is helpful in treating symptoms of the common cold and flu, sinusitis, asthma, and bronchitis. Due to its central nervous system (CNS) stimulant properties and structural similarity to amphetamine, it is also used for non-medical purposes such as doping agent, to increase focus, and as a substance that gets rid of exhaustion and drowsiness. Neverthe

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