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Journal articles on the topic 'Synchronous cancers'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Ciolofan, Mircea Sorin, Florin Anghelina, Alexandru Nicolae Vlăescu, et al. "Synchronous laryngeal cancer." Romanian Journal of Morphology and Embryology 65, no. 2 (2024): 309–15. http://dx.doi.org/10.47162/rjme.65.2.18.

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Multiple primary cancers are usually defined as primary malignant tumors of different histological origins in one person. Synchronous cancers are defined as two or more primary cancers diagnosed in the same patient at the same time or within six months after identifying the first tumor, and those cancers that develop at more than a six-month interval are termed as metachronous multiple primary cancers. Our study comprised of a patient with synchronous laryngeal cancer with double localizations. The case was solved through surgical excision of the tumors. Histopathological and immunohistochemis

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2

Androutsopoulos, G., and G. Decavalas. "Synchronous Primary Endometrial and Ovarian Cancers: Pathogenesis, Treatment and Prognosis." International Journal of Clinical Therapeutics and Diagnosis 2, no. 4e (2014): 1–2. https://doi.org/10.19070/2332-2926-140005e.

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Synchronous primary cancers are relatively uncommon in general population. Only 0.5-1.7% of women with gynecological malignancies, have synchronous primary cancers of the female genital tract. Among them, the most common combination is synchronous primary endometrial and ovarian cancers.

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3

Menkiti, Felix E., Ifeoma F. Ezejiofor, Michael E. Chiemeka, and Chukwudi R. Osakwe. "Synchronous Endometrial Malignant Mixed Mullerian Tumor and Ovarian High-Grade Serous Carcinoma: A Case Report and Review of Literature." Asian Journal of Oncology 05, no. 02 (2019): 089–92. http://dx.doi.org/10.1055/s-0039-3401368.

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AbstractSynchronous cancers account for 0.7 to 1.8% of all gynecologic malignancies. Although synchronous endometrial and ovarian cancers are well reported in the literature, they are largely synchronous endometrioid cancers; no reported case of synchronous endometrial malignant mixed Mullerian tumor (MMMT) and ovarian serous carcinoma is seen. We therefore report a case of synchronous endometrial MMMT and ovarian serous carcinoma in a 60-year-old Nigerian female.

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Crocetti, Emanuele, Stefania Arniani, and Eva Buiatti. "Synchronous and Metachronous Diagnosis of Multiple Primary Cancers." Tumori Journal 84, no. 1 (1998): 9–13. http://dx.doi.org/10.1177/030089169808400102.

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Aims In the time period near to the diagnosis of a new cancer, other tumors (synchronous cancers), especially slow-growing tumors, may be detected because several diagnostic examinations are performed. The frequency of synchronous in comparison with metachronous carcinomas has been evaluated in a population-based series of multiple primary cancers. Methods The case series of multiple primary cancers of the Tuscany Tumor Registry, incident during the period 1985-1991 was analyzed. For each site of a second independent tumor, the proportions of synchronous (diagnosed within 2 months of the first

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5

Islam, M. M. Shahin Ul, Mst Naznin Sarker, Syeda Nur E. Jannat, et al. "Synchronous Upper GIT Malignancy in an Elderly Patient." Bangabandhu Sheikh Mujib Medical College Journal 1, no. 2 (2023): 107–9. http://dx.doi.org/10.3329/bsmmcj.v1i2.69351.

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Previously thought that, synchronous colonic cancers are relatively common but synchronous upper gastrointestinal cancers are relatively uncommon. But now a days, frequency of synchronous esophageal cancers, gastric cancers or duodenal cancers is increasing due to availability of the upper GI endoscopy, and the prolonged life span of the general population. Here we discussed anelderly malewho presented with features of gastric outlet obstruction and dysphagia and finally diagnosed as simultaneous esophageal squamous cell carcinoma and gastric adenocarcinoma. Bangabandhu Sheikh Mujib Med.

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6

Lee, K., H. Jang, M. Choi, et al. "Clinical analysis of multiple primary cancers." Journal of Clinical Oncology 25, no. 18_suppl (2007): 19639. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.19639.

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19639 Background: Multiple primary cancers are defined as two or more abnormal growths of tissue occurring simultaneously or abnormal growths of tissues that follow a previous neoplasm but are not metastases of the latter in the same individual. The primary objective of this study was to determine the occurrence, clinical characteristics and prognosis of multiple primary cancers in single institution, respectively. Methods: Between January 1995 and June 2006, patients with multiple primary cancers were selected from a review of patients who had been treated and followed-up in our Ewha Womans U

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7

Sercombe, Ashleigh M., and Damian Fry. "A rare case of three synchronous colorectal cancers and a closed loop large bowel obstruction." International Surgery Journal 9, no. 4 (2022): 870. http://dx.doi.org/10.18203/2349-2902.isj20220948.

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Colorectal malignancies are a common general surgical presentation. However, synchronous colorectal cancers are less frequent and typically account for only 3.5% of all colorectal cancers. Of these 3.5% of synchronous colorectal cancers, only approximately 4% are incidental appendiceal malignancies. An 80-year-old gentleman presented with abdominal pain and distension to the emergency department. On examination, the patient had a peritonitic abdomen and a CT scan revealed a large bowel obstruction secondary to sigmoid and rectal neoplasms, concerning for a closed loop obstruction. He underwent

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8

Bharaswadkar, Ganesh B., and Nalan Babacan. "Synchronous papillary endometrial and ovarian cancer in a 64-year-old woman." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 11, no. 1 (2021): 252. http://dx.doi.org/10.18203/2320-1770.ijrcog20215113.

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Obesity, nulliparity, and comparatively younger age may attribute a “hormonal field effect” which leads to the development of synchronous endometrioid cancers. The morphological unit consisting of the uterus, fallopian tubes, and ovary as part of the Mullerian system may explain the synchronous appearance of these malignancies. Synchronous endometrial and ovarian cancer (SEOC) is defined as the simultaneous presence of these dual cancers at the time of diagnosis as opposed to metachronous cancer where these two cancers are diagnosed at different chronologic time points. Synchronous malignancie

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9

Terzakis, Emmanouil, Georgios Androutsopoulos, Charalampos Grigoriadis, et al. "Synchronous primary endometrial and fallopian tube cancers." Eur J Gynaecol Oncol 31, no. 4 (2010): 467–68. https://doi.org/10.5281/zenodo.6033922.

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Background: Synchronous primary cancers are relatively uncommon in general population. We present a case of synchronous primary endometrial and fallopian tube cancers and review the literature. Case: The patient, a 54-year-old, gravida 2, para 2 postmenopausal Greek woman presented with a complaint of abnormal vaginal bleeding. She underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy and total omentectomy. The histopathology revealed synchronous primary cancers of the endometrium and right fallopian tube. She underwent to postoperative chemotherapy and postoperative radi

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10

Lin, Yi-Jia, Hua-Xian Chen, Feng-Xiang Zhang, et al. "Features of synchronous and metachronous dual primary gastric and colorectal cancer." World Journal of Gastrointestinal Oncology 15, no. 11 (2023): 1864–73. http://dx.doi.org/10.4251/wjgo.v15.i11.1864.

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BACKGROUND Studies evaluating the characteristics of dual primary gastric and colorectal cancer (CRC) (DPGCC) are limited. AIM To analyze the clinicopathologic characteristics and prognosis of synchronous and metachronous cancers in patients with DPGCC. METHODS From October 2010 to August 2021, patients with DPGCC were retrospectively reviewed. The patients with DPGCC were divided into two groups (synchronous and metachronous). We compared the overall survival (OS) between the groups using Kaplan-Meier survival methods. Univariate and multivariate analyses were performed using Cox’s proportion

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11

Samad, Afra, Madiha Syed, and Arbaz Samad. "A case report of rare synchronous primary cancer in genital tract of middle aged female: Synchronous primary endometrial adenocarcinoma and serous papillary cystadenocarcinoma of ovary." Professional Medical Journal 27, no. 02 (2020): 437–41. http://dx.doi.org/10.29309/tpmj/2020.27.02.3313.

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Synchronous cancers are defined as two or more histologically distinct malignancies arising in the same site, following each other in a sequence of < 2 months. Synchronous primary cancers are rare in general population and account for only 0.5-1.7% of gynaecological malignancies.1,2 It is important to distinguish synchronous primary tumors from metastatic malignancies.3 Case Report: We report a case of 55 years old female with history of pain in abdomen for the last one year. Surgical intervention was planned after complete work up. Hysterectomy with bilateral salpingo-oophorectomy and omen

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12

Androutsopoulos, Georgios, Charalampos Vitsas, Nikolaos Thanatsis, Georgios Michail, Emmanouil Terzakis, and Georgios Decavalas. "Clinical characteristics and current therapeutic approach of patients with synchronous primary endometrial and ovarian cancers." Hel J Obst Gynecol 13, no. 4 (2014): 109–14. https://doi.org/10.5281/zenodo.6012619.

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Synchronous primary endometrial and ovarian cancers are relatively uncommon in general population. Although their pathogenesis still remains unclear, embryologic, hormonal, genetic or other phenomena may be responsible for the development of synchronous primary endometrial and ovarian cancers. The most common symptoms and signs in those patients, are: abnormal uterine bleeding, abdominal/pelvic pain and abdominal/pelvic mass. For most patients with synchronous primary endometrial and ovarian cancers, systematic surgical staging is the baseline therapy and includes: total abdominal hysterectomy

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13

Ferguson, Mark K. "Synchronous Primary Lung Cancers." Chest 103, no. 4 (1993): 398S—400S. http://dx.doi.org/10.1378/chest.103.4_supplement.398s.

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14

Kambouche, Faouzia, and Mokhtar Riadh Mohammed. "Multiple primary cancers: a case report and literature review." International Journal of Medicine 11, no. 2 (2023): 17–19. http://dx.doi.org/10.14419/2mkcax16.

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The fortuitous discovery of synchronous double primary cancers of the lung and stomach is relatively rare, but the discovery of triple primary cancers in one patient remains exceptional. The discovery of triple primary cancers in a single patient remains exceptional. This coexistence corresponds to the syndrome of multiple primary malignancies or multiple primary cancers (MPC). We present a case of synchronous association of squamous cell carcinoma of the lung and gastric adenocarcinoma with a history of mature squamous cell carcinoma of the larynx.

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15

Taylor, Jacob, Adam B. Weiner, Binhuan Wang, Arjun V. Balar, Gary D. Steinberg, and Richard S. Matulewicz. "Lung Metastases Versus Second Primary Lung Cancers in Patients with Primary Urothelial Carcinoma of the Bladder: A National Population-Based Assessment." Bladder Cancer 7, no. 3 (2021): 347–54. http://dx.doi.org/10.3233/blc-210008.

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BACKGROUND: The work-up and diagnosis of indeterminate lung nodules at time of bladder cancer diagnosis may delay or change treatment. OBJECTIVE: To quantify the incidence of synchronous and metachronous lung cancers in adults with bladder cancer and compare these rates to the incidence of bladder cancer metastases in the lung. METHODS: We retrospectively analyzed all adults diagnosed with bladder cancer in the Surveillance, Epidemiology and End Results (SEER) registry (2010– 2015) and identified second primary lung cancers defined as being either synchronous (diagnosed within 6 months of blad

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16

Forrest, Allison, Numbereye Numbere, Jerome Jean-Gilles, Thomas Frye, and Vikram Dogra. "Sonographic Diagnosis of Unilateral Synchronous Testicular Tumors." American Journal of Sonography 2 (April 15, 2019): 2. http://dx.doi.org/10.25259/ajs-3-2019.

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Testicular cancer accounts for 1% of all male cancers yet is the most common cancer affecting men aged 15–44 years. Most testicular cancers are seminomas or non-seminomatous germ cell tumors. Rarely, multiple testicular cancers may occur simultaneously, most often of the same histological type. However, synchronous tumors of different histological types may occur, although rarely. In this case study, we present the sonographic features with histopathologic correlation in a case of unilateral synchronous testicular tumors of discordant histology.

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17

Androutsopoulos, Georgios, and Georgios Decavalas. "Synchronous primary endometrial and ovarian cancers." J Community Med Health Edu 3, no. 7 (2013): e120. https://doi.org/10.4172/2161-0711.1000e120.

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18

Shenoy, Santosh. "Synchronous gastric and colon cancers: Important to consider hereditary syndromes and chronic inflammatory disease associations." World Journal of Gastrointestinal Oncology 16, no. 3 (2024): 571–76. http://dx.doi.org/10.4251/wjgo.v16.i3.571.

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In this editorial we comment on the manuscript, describing management and surveillance strategies in synchronous and metachronous, gastric and colon cancers. Synchronous or metachronous primary malignancies at different sites of the gastrointestinal tract pose a unique diagnostic and therapeutic challenge. Multidisciplinary services and strategies are required for the management of multiple site primary malignancies, to provide the best oncological outcomes. Although this study highlights the dual cancers in 76 sporadic cases, the authors excluded 55 patients due to combination of factors whic

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Albertsdottir, Elin, and Jacob Juel. "Quadruple synchronous primary cancers in a single patient." BMJ Case Reports 13, no. 4 (2020): e233326. http://dx.doi.org/10.1136/bcr-2019-233326.

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Patients diagnosed with quadruple synchronous primary cancers are extremely rare and we present here, to the best of our knowledge, the first case report of this combination of primary cancers. A 70-year-old woman was diagnosed with cervical adenocarcinoma, melanoma on the right leg, invasive ductal cell carcinoma metastasis in the left axilla with no primary breast tumour detected and multiple basal cell carcinomas on the limbs, all within 2 months. The management was conducted in collaboration with six medical specialties. The cancers were surgically managed, with further adjuvant chemothera

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Hirano, Tomonori, Nobuyuki Kakiuchi, Takeuchi Yasuhide, et al. "Abstract 6198: Genetic analysis of synchronous or metachronous multiple pancreatic cancers." Cancer Research 82, no. 12_Supplement (2022): 6198. http://dx.doi.org/10.1158/1538-7445.am2022-6198.

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Abstract [Introduction] The majority of patients with pancreatic cancer are inoperable at the time of diagnosis and even those cases with successful tumor resection for early-stage tumors frequently had second tumors within the remaining pancreas shortly after the surgery, contributing to a poor clinical outcome. Moreover, synchronous multiple pancreatic cancers were often reported. One of the long-standing issues about such synchronous and/or metachronous multiple pancreatic cancers is their clonal origins. In this study, we aimed to reveal the origin of multiple pancreatic cancers using an u

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21

Henderson, Jacob, Daniel Morgenstern, Melissa Edwards, et al. "IMMU-14. IMMUNE CHECKPOINT INHIBITOR THERAPY FOR TREATMENT OF SYNCHRONOUS CANCERS IN PAEDIATRIC PATIENTS WITH CONSTITUTIONAL MISMATCH REPAIR DEFICIENCY." Neuro-Oncology 22, Supplement_3 (2020): iii362. http://dx.doi.org/10.1093/neuonc/noaa222.370.

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Abstract Constitutional mismatch repair deficiency (CMMRD) is an autosomal recessive condition in which affected patients carry biallelic germline mutations in the MMR genes. This highly penetrant syndrome results in nearly universal development of malignant neoplasms at a young age, most commonly pediatric brain tumors. Importantly, in addition to brain tumors, patients frequently develop multiple metachronous or even synchronous tumors making it impossible to treat these cancers with current chemotherapeutic approaches due to the complexity of different chemoradiation regimens required, resu

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Edfelt, Elias, Mehrnoosh Shahrivar, Karin Holmsten, and Cecilia Radkiewicz. "Rising incidence trends of synchronous prostate and rectal cancers: a population-based study." Acta Oncologica 64 (March 7, 2025): 374–79. https://doi.org/10.2340/1651-226x.2025.42592.

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Background: There is a lack of comprehensive reports on time trends in synchronous prostate and rectal cancers. To address this, we conducted the largest cohort study to date to assess these trends in a population-based setting. Methods: We included all adult (ages 18−99) men with incident prostate cancer in the Swedish Cancer Register in 1993−2019. Age-standardized incidence rates (ASIRs) of prostate cancer per 100,000 male population per year were calculated and compared to the ASIR of synchronous (± 6 months from rectal cancer diagnosis) prostate cancer. Age-adjusted synchronous-to-general

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23

Komiyama, Shinichi, Eiji Nishio, Ryoko Ichikawa, et al. "Asymptomatic Synchronous Quintuple Primary Cancers." Gynecologic and Obstetric Investigation 74, no. 4 (2012): 324–28. http://dx.doi.org/10.1159/000339135.

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24

WYSOCKI, WOJCIECH M., ANDRZEJ L. KOMOROWSKI, LESZEK S. KOLODZIEJSKI, and JOANNA WYSOCKA. "Synchronous anal and penile cancers." International Journal of Urology 11, no. 12 (2004): 1139–41. http://dx.doi.org/10.1111/j.1442-2042.2004.00955.x.

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Aminian, Ali, Rasoul Mirsharifi, Mohsen Kalhor, et al. "Synchronous esophageal and gastric cancers." Indian Journal of Surgery 70, no. 4 (2008): 205–6. http://dx.doi.org/10.1007/s12262-008-0057-1.

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Li, Hui, Shengcai Hou, and Bin Hu. "P3-242: Synchronous lung cancers." Journal of Thoracic Oncology 2, no. 8 (2007): S782. http://dx.doi.org/10.1097/01.jto.0000284217.40990.e3.

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27

Patel, Subhash. "Three Synchronous Multiorgan Primary Cancers." Archives of Surgery 120, no. 10 (1985): 1182. http://dx.doi.org/10.1001/archsurg.1985.01390340078016.

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Selvakumar, Veda, Shubha Garg, Kahkasha Siddiqui, Ashish Goel, Kapil Kumar, and Rajeev Kumar. "Tailored approach to management of bilateral breast cancer in Indian women." Asian Journal of Oncology 01, no. 02 (2015): 097–100. http://dx.doi.org/10.4103/2454-6798.173311.

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ABSTRACT Introduction: Bilateral breast cancer BCC is relatively uncommon with an overall incidence of 5–20% in women with early breast cancer. They are divided into synchronous if cancers are detected simultaneously or within 6 months of each other and metachronous if they are detected more than 6 months apart from each other. Family history and hereditary cancers multicentricity and lobular histology are some of the factors associated with BCC. In this background, we sought to evaluate the incidence, clinicopathological profile, and management of women with bilateral primary breast cancer at

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Androutsopoulos, Georgios, and Georgios Decavalas. "Recent advances in the management of synchronous primary endometrial and ovarian cancers." Insights Obstet Gynecol 1 (September 8, 2016): 1.1. https://doi.org/10.5281/zenodo.6060828.

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Synchronous primary cancers are very rare in the general population. Especially in malignancies of the female genital tract, only a small proportion between 0.5 and 1.7 % are synchronous primary cancers. Among them, synchronous primary endometrial and ovarian cancers (SPEOC) remains the most common combination. Recent years, many international scientific societies (ACOG, FIGO and ESMO) have recommended systematic surgical staging as the initial treatment approach in patients with malignancies of the female genital tract. It is worth noting, that pelvic and para-aortic lymphadenectomy plays an

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30

Bae, Ja Seong, Jun Ho Lee, Keun Won Ryu, Young Woo Kim, and Jae Moon Bae. "Characteristics of Synchronous Cancers in Gastric Cancer Patients." Cancer Research and Treatment 38, no. 1 (2006): 25. http://dx.doi.org/10.4143/crt.2006.38.1.25.

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Chatterjee, Goutomi, Neha Rastogi, Anil Sharma, Rohit Kapoor, Dhwanee Thakkar, and Satya Prakash Yadav. "Synchronous cancers: Are we missing hereditary cancer syndromes?" Pediatric Hematology Oncology Journal 4, no. 2 (2019): S16. http://dx.doi.org/10.1016/j.phoj.2019.08.041.

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Hirano, Tomonori, Nobuyuki Kakiuchi, Yasuhide Takeuchi, et al. "Abstract 1511: Origin of synchronous or metachronous multiple pancreatic cancers." Cancer Research 83, no. 7_Supplement (2023): 1511. http://dx.doi.org/10.1158/1538-7445.am2023-1511.

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Abstract Introduction: The majority of patients with pancreatic cancer are inoperable at the time of diagnosis and even those cases with successful tumor resection for early-stage tumors frequently had second tumors within the remaining pancreas shortly after the surgery, contributing to a poor clinical outcome. Moreover, synchronous multiple pancreatic cancers were often reported. One of the long-standing issues about such synchronous and/or metachronous multiple pancreatic cancers is their clonal origins. In this study, we aimed to reveal the origin of multiple pancreatic cancers using an un

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Hirano, Tomonori, Nobuyuki Kakiuchi, Yasuhide Takeuchi, et al. "Abstract 5659: Origin of synchronous or metachronous multiple pancreatic cancers." Cancer Research 84, no. 6_Supplement (2024): 5659. http://dx.doi.org/10.1158/1538-7445.am2024-5659.

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Abstract [Introduction] The majority of patients with pancreatic cancer are inoperable at the time of diagnosis and even those cases with successful tumor resection for early-stage tumors frequently had second tumors within the remaining pancreas shortly after the surgery, contributing to a poor clinical outcome. Additionally, synchronous multiple pancreatic cancers have been frequently documented. One of the long-standing issues about such synchronous and/or metachronous multiple pancreatic cancers is their clonal origins. This study is designed to elucidate the origin of multiple pancreatic

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Decavalas, Georgios, Georgios Adonakis, Georgios Androutsopoulos, et al. "Synchronous primary endometrial and ovarian cancers: a case report." Eur J Gynaecol Oncol 27, no. 4 (2006): 434–36. https://doi.org/10.5281/zenodo.6026567.

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Synchronous primary cancers of the endometrium and ovary are relatively uncommon in general population. The patient, a 49-year-old postmenopausal Greek woman presented with abdominal pain and pelvic mass. She underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy, total omentectomy, appendectomy and pelvic lymph node dissection. The histopathology revealed synchronous primary cancers of the endometrium and right ovary. She underwent postoperative chemotherapy. Thirty nine months after surgery, she remains well without evidence of recurrence.

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DoĞAn Ekici, A. IŞIN, T. KÜÇÜKali, M. COŞKUN Salman, and A. Ayhan. "Triple simultaneous primary gynecological malignancies in a 56-year-old patient." International Journal of Gynecologic Cancer 16, no. 5 (2006): 1947–50. http://dx.doi.org/10.1136/ijgc-00009577-200609000-00036.

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The occurrence of double simultaneous primary cancers is common. However, the occurrence of synchronous primary triple gynecological malignancies is an extremely rare event. In this report, the clinical and pathologic findings of a 56-year-old female patient with synchronous triple primary gynecological cancers including well-differentiated ovarian mucinous cystadenocarcinoma, well-differentiated endometrial endometrioid adenocarcinoma, and uterine leiomyosarcoma were presented. Synchronous primary, well-differentiated endometrial endometrioid adenocarcinoma and leiomyosarcoma of uterus withou

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Garcia, Diogo, Isa Mambetsariev, Jeremy Fricke, et al. "Complete response to chemoimmunotherapy with bevacizumab in synchronous multiple primary cancers: pulmonary adenocarcinoma and sarcomatoid carcinoma." Molecular Case Studies 9, no. 2 (2023): a006262. http://dx.doi.org/10.1101/mcs.a006262.

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A small percentage of patients have multiple synchronous primary cancers at presentation. In the last five years, many regimens associated with immunotherapy and chemotherapy were approved for first-line metastatic non-small-cell lung cancer (NSCLC) and other solid tumors, but the study of immunotherapy when multiple cancers are present in one patient remains incomplete. Next-generation sequencing biomarkers and immunotherapy markers including PD-L1 can be effectively utilized in the diagnosis and treatment plan for multiple synchronous primary cancers. Immune biomarkers and PD-L1 expression w

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Podolskiy, V. V., and E. A. Podolskaya. "Synchronous multiple primary colorectal cancer in patients with extraintestinal malignancies." Siberian journal of oncology 24, no. 2 (2025): 101–7. https://doi.org/10.21294/1814-4861-2025-24-2-101-107.

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Introduction. The incidence of colorectal cancer (CRC) is steadily increasing in Russia. Patients with cancers of extra-intestinal malignancies are at increased risk of developing CRC. However, currently, there is no a science-based screening system for synchronous primary-multiple CRC among this group of patients. The aim of the study was to analyze features of synchronous CRC among patients with extra-intestinal malignancies. Material and Methods. The medical records of 53 cancer patients registered at the Kursk Oncology Research and Clinical Center named after G.E. Ostroverkhov were analyze

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Takeda, Mitsunobu, Yoshihito Ide, Masayoshi Tokuoka, Hajime Hirose, and Yo Sasaki. "Utility of Laparoscopic Surgery for Multiple Synchronous Colorectal Cancers With Two Anastomotic Sites." International Surgery 102, no. 1-2 (2017): 15–20. http://dx.doi.org/10.9738/intsurg-d-17-00004.1.

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The frequency of multiple synchronous colorectal cancers is reported to be 2% to 7%. The surgical resection of 2 lesions and having 2 anastomotic sites are rare. According to previous studies, even if there are 2 anastomotic sites, the rate of complications associated with laparotomy will not increase. However, the number of studies confined to cases of laparoscopic surgery is limited. This study investigated effective methods for laparoscopic colorectal resection and their short-term results in cases of multiple synchronous colorectal cancers with 2 anastomotic sites. The safety of these meth

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Koike, Hirofumi, Hirokazu Kurohama, Takaaki Nakamura, et al. "First reported case of a synchronous occurrence of cervical carcinosarcoma and endometrial adenocarcinoma showing radiological differentiation on MRI: A case report and diagnostic challenges." Journal of Case Reports and Images in Obstetrics and Gynecology 11, no. 1 (2025): 35–41. https://doi.org/10.5348/100196z08hk2025cr.

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Introduction: Synchronous cancer, which is when a secondary cancer occurs simultaneously or within six months of a primary cancer diagnosis, is rare for malignant female genital tract neoplasms. Despite cervical and endometrial cancers being very common gynecologic malignancies, they do not frequently occur synchronously. Case Report: Here, we report a case of a 49-year-old female patient with a synchronous occurrence of endometrial adenocarcinoma and cervical carcinosarcoma (CCS), an extremely rare and aggressive cervical cancer subtype. Transvaginal ultrasonography showed two non-contiguous

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Lim, Geok Hoon, Jing Xue Hoo, You Chan Shin, Rachel Zhi Ting Choo, Fuh Yong Wong, and John Carson Allen. "Is Metastatic Staging Needed for All Patients with Synchronous Bilateral Breast Cancers?" Cancers 16, no. 1 (2023): 17. http://dx.doi.org/10.3390/cancers16010017.

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Background: Patients with bilateral breast cancers are uncommon and are associated with a poorer prognosis. While metastatic staging guidelines in patients with unilateral cancer were established, the indication of metastatic staging in patients with bilateral breast cancers is unclear. We aimed to determine which patients with synchronous bilateral breast cancers require metastatic staging at diagnosis. This is the first such reported study, to the best of our knowledge. Methods: A retrospective review of newly diagnosed synchronous bilateral invasive breast cancer patients at our institution

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Rajenderkumar, D., K. K. K. Chan, K. A. Hayward, and R. D. R. McRae. "Bilateral synchronous tonsillar carcinoma." Journal of Laryngology & Otology 113, no. 3 (1999): 255–57. http://dx.doi.org/10.1017/s0022215100143713.

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AbstractSynchronous cancers occur in four per cent of patients with head and neck malignancies but no bilateral synchronous tonsillar carcinomas have been described in the English literature. We describe the first such case and discuss the prognostic aspect of this carcinoma. In the presence of contralateral neck nodes in patients with head and neck malignancies, a careful search should be made for a second head and neck primary.

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Bassel, Said, Smail Sourni, Dounia Douah, et al. "Synchronous Papillary Thyroid Carcinoma and Right Colon Cancer." SAS Journal of Surgery 10, no. 09 (2024): 1076–78. http://dx.doi.org/10.36347/sasjs.2024.v10i09.013.

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Multiple primary cancers (MPC) are relatively rare, but their incidence has been increasing in recent decades. This can be the result of advances in cancer diagnostic and therapeutic strategies. We present a new observation of synchronous primary thyroid and colon cancers occurring in a 55-year-old patient and we discuss, in the light of a review literature, the various environmental factors, genetic and iatrogenic involved in the appearance of a second primary cancer.

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Gwak, Hongki, Sung Hoo Jung, Young Jin Suh, et al. "Prognostic Impact of Multiple Synchronous T1 Breast Cancer." Cancers 16, no. 23 (2024): 4019. https://doi.org/10.3390/cancers16234019.

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Background/Objectives: The reported incidence of multiple breast cancers varies widely, ranging from 6 to 60%, depending on the definitions used and methods of detection. With advancements in preoperative imaging techniques, such as magnetic resonance imaging, the detection of multiple breast cancers has improved. However, the clinical significance of multiple breast cancers remains controversial, with conflicting results regarding their impact on prognosis. We investigated the association between the number of synchronous ipsilateral T1 breast tumors, overall survival (OS), and breast cancer-

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Abushwemeh, Mohammed Ayed, Nusrat Jabeen, Asma Al Qaseer, Mohamed Isa, Amal Al Rayes, and Raed Al Marzooq. "Synchronous breast and colon cancer in a young female: a single stage surgery." International Surgery Journal 8, no. 4 (2021): 1309. http://dx.doi.org/10.18203/2349-2902.isj20211317.

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Synchronous breast and colon cancers are rare, particularly in the absence of family history. Synchronous tumors should always be kept in mind during the staging workup for the primary malignancy. There are no definitive guidelines for the management of synchronous tumors, thus the involvement of tumour board multidisciplinary team is essential. We present a case of a young female patient who was diagnosed with synchronous breast and colon cancer. A handful of synchronous breast and colon cancer cases have been reported and operated at intervals, but up to our knowledge this is the first case

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Mehta, Rutika Jitesh, Adrienne Groman, Rohit K. Jain, and Ellis Glenn Levine. "Trends in synchronous invasive ductal carcinomas of the breast: A SEER database analysis." Journal of Clinical Oncology 35, no. 15_suppl (2017): e13081-e13081. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e13081.

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e13081 Background: Synchronous breast cancers are uncommon and account for around 2% of all breast cancer diagnosis. Lobular histology is considered a risk factor for synchronous breast cancers. We sought to study the trends in synchronous breast cancer of ductal histology and influence of age by interrogating the SEER database. Methods: The SEER Research data 1973-2013 was interrogated for synchronous infiltrating ductal carcinoma diagnosis (2 diagnosis within 6 months of each other). Overall survival (OS), the primary endpoint, was defined as the time (in months) from diagnosis to death from

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Fujimura, Yoshinori, Shigeo Inoue, Mitsuo Iida, and Michio Shimizu. "Synchronous multiple gastric cancers associated with familial gastric cancers." Gastrointestinal Endoscopy 51, no. 6 (2000): 742–45. http://dx.doi.org/10.1067/mge.2000.105727.

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Androutsopoulos, Georgios, and Georgios Decavalas. "Synchronous primary endometrial and ovarian cancers: a critical update." Int J Gynecol Clin Pract 2 (January 29, 2015): 106. https://doi.org/10.15344/2394-4986/2015/106.

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Alghafees, Mohammad, Raouf M. Seyam, Turki Al-Hussain, et al. "Using machine learning models to predict synchronous genitourinary cancers among gastrointestinal stromal tumor patients." Urology Annals 16, no. 1 (2024): 94–97. http://dx.doi.org/10.4103/ua.ua_32_23.

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Objectives: Gastrointestinal stromal tumors (GISTs) can occur synchronously with other neoplasms, including the genitourinary (GU) system. Machine learning (ML) may be a valuable tool in predicting synchronous GU tumors in GIST patients, and thus improving prognosis. This study aims to evaluate the use of ML algorithms to predict synchronous GU tumors among GIST patients in a specialist research center in Saudi Arabia. Materials and Methods: We analyzed data from all patients with histopathologically confirmed GIST at our facility from 2003 to 2020. Patient files were reviewed for the presence

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Jain, Kunal S., Andrew G. Sikora, Shrujal S. Baxi, and Luc G. T. Morris. "Synchronous cancers in patients with head and neck cancer." Cancer 119, no. 10 (2013): 1832–37. http://dx.doi.org/10.1002/cncr.27988.

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Eom, Bang Wool, Hyuk-Joon Lee, Moon-Won Yoo, et al. "Synchronous and metachronous cancers in patients with gastric cancer." Journal of Surgical Oncology 98, no. 2 (2008): 106–10. http://dx.doi.org/10.1002/jso.21027.

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