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Journal articles on the topic 'Synchronous Colon Cancer'

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1

International, Journal of Medical Science and Innovative Research (IJMSIR). "Synchronous Colon Cancer and ALK Positive Lung Cancer." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 5 (2024): 37–41. https://doi.org/10.5281/zenodo.15430305.

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<strong>Abstract</strong> We present a case of synchronous ALK positive lung cancer and colon cancer. Patient presented to the hospital for routine health checkup and was incidentally detected with both the cancers. Initially it was thought to be colon cancer with lung metastasis. IHC was done on the lung biopsy specimen which was positive for TTF1 and ALK mutation and negative for SATB2. Colon specimen was also reported as mucinous adenocarcinoma histopathologically but IHC was negative for ALK mutation. Hence the diagnosis of synchronous double malignancy was made. Both the cancers were loca
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2

Abushwemeh, Mohammed Ayed, Nusrat Jabeen, Asma Al Qaseer, Mohamed Isa, Amal Al Rayes, and Raed Al Marzooq. "Synchronous breast and colon cancer in a young female: a single stage surgery." International Surgery Journal 8, no. 4 (2021): 1309. http://dx.doi.org/10.18203/2349-2902.isj20211317.

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Synchronous breast and colon cancers are rare, particularly in the absence of family history. Synchronous tumors should always be kept in mind during the staging workup for the primary malignancy. There are no definitive guidelines for the management of synchronous tumors, thus the involvement of tumour board multidisciplinary team is essential. We present a case of a young female patient who was diagnosed with synchronous breast and colon cancer. A handful of synchronous breast and colon cancer cases have been reported and operated at intervals, but up to our knowledge this is the first case
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3

Jung, Eric E., F. Scott Heinemann, Colt A. Egelston, et al. "Synchronous recurrence of concurrent colon adenocarcinoma and dedifferentiated liposarcoma." BMJ Case Reports 12, no. 5 (2019): e228868. http://dx.doi.org/10.1136/bcr-2018-228868.

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A 62-year-old man presented with concurrent sigmoid colon adenocarcinoma and small bowel mesenteric dedifferentiated liposarcoma. Following surgical resection of the colon cancer, complete excision of the mesenteric sarcoma and adjuvant folinic acid, fluorouracil and oxaliplatin (FOLFOX) chemotherapy, the patient demonstrated no radiological evidence of disease for more than 2 years. The patient then developed synchronous recurrence of both cancers: the colon cancer metastasised to the liver and a pelvic lymph node, and the liposarcoma recurred in the original location. The patient underwent a
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Khatri, Wafa Ibrahim, Hitesh Rajendra Singhavi, Tahoora Sarguroh, et al. "Quadruple Primary Malignancy of the Scalp, Colon, and Prostate in a Single Patient: A Unique Case Report and Review of Literature." Cancer Plus 4, no. 2 (2022): 7. http://dx.doi.org/10.18063/cp.v4i2.337.

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Multiple primary malignancies are rare but early detection can be achieved with the advent of advanced imaging techniques. Diagnosis of all synchronous malignancy is vital for planning and favorable outcome. In this study, we present a case of synchronous triple primary malignancy consisting of squamous carcinoma scalp, adenocarcinoma prostate, and adenocarcinoma ascending colon with history of sigmoid colon cancer 11 years back. There were 12 possible treatment options and three alternative treatment sequences. Multidisciplinary tumor board team decided to begin the treatment with hormonal th
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5

Jolobe, OMP. "MORE ON THE ASSOCIATION OF GASTRIC AND COLONIC NEOPLASMS." Journal of the Royal College of Physicians of Edinburgh 39, no. 4 (2009): 382. https://doi.org/10.1177/1478271520093904039.

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The report of the association of synchronous gastric polyp and colon cancer in the last Journal issue (Cooper H, Dhar A. Synchronous gastric polyp and colonic cancer. J R Coll Physicians Edinb 2009; 39:218-20) has, as its corollary, the occurrence of metastases to the stomach from primary adenocarcinoma of the colon.1 In the latter series there were five such cases, one identified by endoscopy, and four by autopsy. The five cases comprised 7% of 67 examples of primary tumours metastatic to the stomach1. The reverse scenario is exemplified by primary gastric adenocarcinoma metastasising to the
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Bassel, Said, Smail Sourni, Dounia Douah, et al. "Synchronous Papillary Thyroid Carcinoma and Right Colon Cancer." SAS Journal of Surgery 10, no. 09 (2024): 1076–78. http://dx.doi.org/10.36347/sasjs.2024.v10i09.013.

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Multiple primary cancers (MPC) are relatively rare, but their incidence has been increasing in recent decades. This can be the result of advances in cancer diagnostic and therapeutic strategies. We present a new observation of synchronous primary thyroid and colon cancers occurring in a 55-year-old patient and we discuss, in the light of a review literature, the various environmental factors, genetic and iatrogenic involved in the appearance of a second primary cancer.
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7

Edfelt, Elias, Mehrnoosh Shahrivar, Karin Holmsten, and Cecilia Radkiewicz. "Rising incidence trends of synchronous prostate and rectal cancers: a population-based study." Acta Oncologica 64 (March 7, 2025): 374–79. https://doi.org/10.2340/1651-226x.2025.42592.

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Background: There is a lack of comprehensive reports on time trends in synchronous prostate and rectal cancers. To address this, we conducted the largest cohort study to date to assess these trends in a population-based setting. Methods: We included all adult (ages 18−99) men with incident prostate cancer in the Swedish Cancer Register in 1993−2019. Age-standardized incidence rates (ASIRs) of prostate cancer per 100,000 male population per year were calculated and compared to the ASIR of synchronous (± 6 months from rectal cancer diagnosis) prostate cancer. Age-adjusted synchronous-to-general
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8

Roy, Amitesh Chandra, Christos Stelios Karapetis, Cynthia Piantadosi, et al. "Patterns of care for synchronous rectal cancer with liver-only metastasis: Results from the South Australian registry of metastatic colorectal cancer." Journal of Clinical Oncology 35, no. 4_suppl (2017): 701. http://dx.doi.org/10.1200/jco.2017.35.4_suppl.701.

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701 Background: Management of rectal cancer with synchronous liver metastasis is not clear. Optimal timing of radiotherapy, chemotherapy, resection of primary and liver metastasis is debated. Methods: The South Australian Registry for metastatic colorectal cancer has entered all patients with mCRC since 1st February 2006. Registry data were analyzed to assess patient characteristics, therapy received and outcomes for patients with liver only metastasis and synchronous rectal or colon primary. KM analysis was used for survival outcomes. Results: 2677 patents had synchronous mCRC. 42% (n = 1125)
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9

Su, I.-Lin, and Yen-Kung Chen. "Utility of FDG PET/CT in Patient with Synchronous Breast and Colon Cancer." Diagnostics 13, no. 13 (2023): 2293. http://dx.doi.org/10.3390/diagnostics13132293.

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The most common malignancy in women is breast cancer, and the second one is colon cancer. Synchronous breast and colon cancers are rare. Here, we reported a 60-year-old woman with a left breast mass for six months. Biopsy revealed an invasive ductal carcinoma. She underwent 2-[Fluorine-18]fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET)/computed tomography (CT) scan for evaluation of the extent of the disease. FDG PET/CT revealed an advanced left breast cancer with multiple metastases in both regional and distant lymph nodes (in left axilla level I/II, lower paratracheal regio
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10

Mylonakis, E., A. Klimis, G. Vlachos, and M. Glynatsis. "Synchronous colon and advanced gastric cancer." Hellenic Journal of Surgery 84, no. 5 (2012): 314–16. http://dx.doi.org/10.1007/s13126-012-0049-2.

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11

Thiels, Cornelius A., Nimesh D. Naik, John R. Bergquist, et al. "Survival following synchronous colon cancer resection." Journal of Surgical Oncology 114, no. 1 (2016): 80–85. http://dx.doi.org/10.1002/jso.24258.

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12

KONO, HARUKA, TARO YAMANAKA, YUKI NISHIHARA, et al. "BRAF Mutation Heterogeneity Detected Using Circulating Tumor DNA Sequencing in Synchronous Colon Cancer: A Case Report." Cancer Diagnosis & Prognosis 3, no. 5 (2023): 605–8. http://dx.doi.org/10.21873/cdp.10262.

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Background/Aim: Synchronous colorectal cancer, which occurs in approximately 4.8-8.4% of all colorectal cancers, has a genetic profile with a higher rate of v-raf murine sarcoma viral oncogene homolog B1 (BRAF) mutation and microsatellite instability-high than solitary colorectal cancer. However, little information is available on heterogeneity among tumor lesions because of difficulty in performing genetic tests in all lesions in clinical practice. Case Report: A 44-year-old man presented with multiple recurrent lung metastases 42 months after the endoscopic resection of early stage synchrono
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13

Choi, Hyun Ho, Sang Woo Kim, Hyung-Keun Kim, Sung Soo Kim, and Hiun-Suk Chae. "CT and PET-CT for detection of synchronous lesion in patients with colorectal cancer obstruction." Journal of Clinical Oncology 35, no. 4_suppl (2017): 581. http://dx.doi.org/10.1200/jco.2017.35.4_suppl.581.

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581 Background: Full preoperative colonic evaluation is recommended to exclude synchronous lesions. In patients with occlusive colorectal cancers, preoperative colonoscopy may not be possible because of narrowing of the lumen. After colonic stent placement, colonoscopy to the proximal part of the obstruction is feasible. However, a complete preoperative colonoscopy was not possible in some cases. The aim of our study was to evaluate the efficacy of preoperative CT and PET-CT for detection of synchronous neoplasms compared with colonoscopy in colorectal cancer obstruction patients who underwent
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14

Podolskiy, V. V., and E. A. Podolskaya. "Synchronous multiple primary colorectal cancer in patients with extraintestinal malignancies." Siberian journal of oncology 24, no. 2 (2025): 101–7. https://doi.org/10.21294/1814-4861-2025-24-2-101-107.

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Introduction. The incidence of colorectal cancer (CRC) is steadily increasing in Russia. Patients with cancers of extra-intestinal malignancies are at increased risk of developing CRC. However, currently, there is no a science-based screening system for synchronous primary-multiple CRC among this group of patients. The aim of the study was to analyze features of synchronous CRC among patients with extra-intestinal malignancies. Material and Methods. The medical records of 53 cancer patients registered at the Kursk Oncology Research and Clinical Center named after G.E. Ostroverkhov were analyze
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15

Hubers, Jeffrey A., and Anurag Soni. "A Rare Case of Endometrial Cancer Metastatic to the Sigmoid Colon and Small Bowel." Case Reports in Gastrointestinal Medicine 2017 (2017): 1–3. http://dx.doi.org/10.1155/2017/9382486.

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Metastatic endometrial cancer to the small bowel or colon has been described but is quite rare. We present a case of metastatic endometrial cancer with synchronous metastases to the colon and jejunum identified three years after surgical treatment of early stage endometrial cancer.
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16

Song, H., Y. Do, W. Lee, and J. Lee. "Multiple primary cancers in patients with non-Hodgkin’s lymphoma." Journal of Clinical Oncology 24, no. 18_suppl (2006): 17562. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.17562.

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17562 Background: Multiple primary malignant tumors have been documented with increased frequency over the last two decades. An analysis of other primary cancers in individuals with non-Hodgkin’s lymphoma (NHL) can help to elucidate this cancer epidemics and etiology. Methods: The occurrence of multiple malignancy was studied in patients with NHL from 1985 to 2005. Results: One or more additional cancers were observed in 19 patients. Seven were diagnosed prior to, 5 concomitantly with, and 7 after the diagnosis of NHL. The diagnosis of 5 synchronous primary cancer were rectal cancer, squamous
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17

Derwinger, Kristoffer, and Bengt Gustavsson. "A study of Aspects on Gender and Prognosis in Synchronous Colorectal Cancer." Clinical Medicine Insights: Oncology 5 (January 2011): CMO.S7871. http://dx.doi.org/10.4137/cmo.s7871.

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Aim To assess differences in demography, pathology and prognosis with tumor multiplicity in colorectal cancer. Method A retrospective single centre study of all patients surgically treated for a colorectal cancer during 1999–2008 (n = 2524). Patient characteristics, pathology and follow-up data were retrieved. Survival was assessed by overall and cancer specific survival. Results 60 (2.4%) patients had a synchronous cancer (SC), associated with right colon, higher age, more assessed lymph nodes but a lower frequency of stage III/IV disease (42% vs. 52%). There was no overall prognostic differe
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18

Sobhani, I., F. Roudot-Thoraval, F. Mesli, et al. "Outcome of colon cancer patients with synchronous metastases." Journal of Clinical Oncology 27, no. 15_suppl (2009): 4029. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.4029.

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4029 Background: Metastatic colon cancer patients may undergo chemotherapy without colon surgery. However, the outcome of patients has not been evaluated and antiagiogenic agents can not be given. The aim of the present cohort study was to analyse factors influencing patients’ survival. Methods: Consecutive patients [N=228, mean age (sd) 64 (12) yrs, median follow-up 20 mths;84 females] treated in 6 teaching hospitals received chemotherapy for metastatic colonic cancer, either as the first step, or after surgery. Progressive free survival (PFS) was estimated using Kaplan-Meïer method. Factors
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19

Abdulla, Hussain Adnan, Raed Almarzooq, and Amal Alrayes. "Synchronous breast and colon cancer: the importance of multidisciplinary team cancer meetings." BMJ Case Reports 12, no. 12 (2019): e232680. http://dx.doi.org/10.1136/bcr-2019-232680.

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A 58-year-old female patient presented with left breast lump. Mammography and ultrasonography were performed, which reported lesions suspicious of malignancy in the left breast and axilla. Core biopsy of the lesions revealed invasive ductal carcinoma with axillary lymph node metastasis. Staging CT scan (thorax, abdomen and pelvis) identified a coexisting neoplasm in the ascending colon. Colonoscopy was performed and the tumour in the ascending colon was biopsied. Histopathological examination revealed adenocarcinoma. In the multidisciplinary team cancer meeting, it was decided to treat the bre
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20

Austin, Publishing Group. "A Case of Synchronous Rectal Cancer and Right Sided Colon Cancer Treated with Transvaginal NOSES Technique." Annals of Hematology & Oncology 10, no. 5 (2023): 1435. https://doi.org/10.26420/annhematoloncol.2023.1435.

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Abstract <strong>Introduction:</strong>&nbsp;We reported a 53 years old female patient with synchronous rectal cancer and right sided colon cancer who underwent transvaginal NOSES to resect two tumors with no serious postoperative complications. <strong>Case report:</strong>&nbsp;The patient underwent electronic colonoscopy and found two lesions in the intestine, located in the right colon and rectum. Pathological examination confirmed that both lesions were malignant tumors, and the patient was diagnosed with concurrent colon and rectal cancer. After diagnosis, the patient underwent transvagi
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21

Cheong, Ju Yong, Raymond Oliphant, and Anil Keshava. "Tale of two cancers: don't forget the synchronous colon cancer!" ANZ Journal of Surgery 89, no. 1-2 (2017): 122–23. http://dx.doi.org/10.1111/ans.13970.

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22

Trifunovic, Bratislav, Branimir Neskovic, Mihailo Bezmarevic, Jovan Krsic, Milic Veljovic, and Dejan Zeljkovic. "Synchronous gastric and colonic cancer: A case report." Vojnosanitetski pregled 72, no. 7 (2015): 642–45. http://dx.doi.org/10.2298/vsp140626056t.

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Introduction. Synchronous gastric and colorectal cancer is present in 4% of cases, commonly as additional finding. This is the case of invasive, synchronous gastric and sigmoid colon cancer. Case report. A 63-years-old male patient admitted to our institution complaining on pains in epigastrium, vomiting, rapid weight loss and occasional constipation. Using the method of esophagogastroduodenoscopy (EGD) the presence of ulcero-infiltrative tumor of gastric fundus was verified, and colonoscopy revealed stenosing tumor of sigmoid colon. Undergoing a multislice computed tomography (MSCT) of the th
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Ganapathi, Senthil Kumar, Harish Kakkilaya, Sathiyamoorthy Rudramurthy, et al. "Subtotal Colectomy is a Safe, Effective, and Well-tolerated Single-stage Treatment for Acute Left Colonic Malignant Obstruction." Indian Journal of Colo-Rectal Surgery 7, no. 1 (2024): 3–8. https://doi.org/10.4103/ijcs.ijcs_9_23.

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ABSTRACT Purpose: Primary resection and anastomosis for malignant acute obstruction of the left colon offers a single-stage surgical option without a stoma. Our aim was to determine the outcome of subtotal colectomy in acutely obstructed left colonic cancer. Methods: A retrospective review of all patients who underwent subtotal colectomy for acutely obstructed left colon cancer over 10 years was performed. All procedures were performed by specialist colorectal surgeons. The primary objective was to analyze the anastomotic leak rate and the functional outcome measured in terms of frequency of b
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Polynovskiy, A., D. Kuz'michev, Z. Mamedli, et al. "Successful Case of Treatment the Patient with Synchronous Rectal and Sigmoid Cancers and Synchronous Lung Metastasis." Medical Radiology and radiation safety 66, no. 3 (2021): 76–81. http://dx.doi.org/10.12737/1024-6177-2021-66-3-76-81.

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Colorectal cancers (CRC) takes the leading position in the incidence of morbidity and mortality worldwide. Metastatic CRC in the primary diagnosis ranges from 15 to 35 %. Lung metastasis are the most frequent extraperitoneal manifestation of the metastatic process. Such patients are relatively rare and there are no clear recommendations for their treatment tactics to date. This clinical case describes a successful strategy of using preoperative prolonged chemoradiotherapy on a primary tumor and stereotactic irradiation of lung metastasis, with courses of chemotherapy, with further radical lapa
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UEDA, Hirofumi, Eiji NAKATA, Isao KAWAI, Toshiyuki TENJYO, Mariko ARAKI, and Chihiro HIGASHI. "Obstructive Colon Cancer with Synchronous Multiple Colon Cancers Preoperatively Diagnosed after Colonic Stent Insertion." Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 76, no. 12 (2015): 3034–37. http://dx.doi.org/10.3919/jjsa.76.3034.

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26

Krashenkov, Oleg, Igor Ivanikov, Oleg Konovalov, et al. "The structure of synchronous multiple primary colorectal cancer." Archiv Euromedica 12, no. 2 (2022): 97–99. http://dx.doi.org/10.35630/2199-885x/2022/12/2.26.

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One of the problems of modern oncology is the lack of timely diagnosis of synchronous forms of colorectal cancer. Therefore, the aim of this study was to evaluate the structure of synchronous primary multiple forms of colorectal cancer. Methods: We analyzed the results of colorectal cancer diagnostics (n = 583) in the period 2010–2019. We did not include patients with metachronous colorectal cancer in the study. The average age of all patients was 71.6 ± 7.4 years. There were 1.5 times more men than women. Results: Synchronous colorectal cancer was detected in 171 (29.3%) patients. With synchr
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Akgül, Nedim, Volkan Doğru, Ebubekir Gündeş, and Ayhan Mesci. "A Rare Case: Synchronous Gastric and Colon Cancer." Turkish Journal of Colorectal Disease 26, no. 4 (2016): 130–32. http://dx.doi.org/10.4274/tjcd.67699.

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28

Deme, Dániel, Abdulfatah M. Bishr, Jamool Nizar, and András Telekes. "Személyre szabott kezelés szinkrón, nyirokcsomó-pozitív petefészek- és vastagbéldaganatban." Orvosi Hetilap 156, no. 23 (2015): 939–43. http://dx.doi.org/10.1556/650.2015.30169.

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A 71-year-old female patient underwent urgent laparotomy due to severe right lower quadrant abdominal pain and fever. Macroscopically duplex coecal and transverse colon cancer as well as a sigmoid or left ovarian cancer were suspected. Pathological findings revealed synchronous left ovarian and transverse colonic neoplasms. Both primaries metastatized to their regional lymph nodes. Furthermore, the ovarian cancer infiltrating the sigmoid colon gave distant metastasis in the coecum, too. Ovarian cancer histology showed papillary adenocarcinoma, and transverse colon cancer was a tubular adenocar
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Avesani, Ettore Contessini, Ugo Cioffi, Matilde De Simone, Fiorenzo Botti, Alberto Carrara, and Stefano Ferrero. "Synchronous Isolated Splenic Metastasis From Colon Carcinoma." American Journal of Clinical Oncology 24, no. 3 (2001): 311–12. http://dx.doi.org/10.1097/00000421-200106000-00021.

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30

Kovalenko, V. L., and A. V. Stepochkin. "Possibilities of surgical treatment of synchronous colon and stomach cancer in a 77-year-old patient." Public health of the Far East Peer-reviewed scientific and practical journal 3, no. 89 (2021): 45–47. http://dx.doi.org/10.33454/1728-1261-2021-3-45-47.

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31

Liao, Haihong, Pengtao Song, Quan Qi, et al. "Synchronous primary malignancy of colon cancer and mantle cell lymphoma: A case report." Open Medicine 16, no. 1 (2021): 696–702. http://dx.doi.org/10.1515/med-2020-0239.

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Abstract Multiple primary malignancies in a single patient are relatively rare; however, the frequency of this has increased significantly in recent decades. Here, we retrospectively reported an unusual case of a 70-year-old man who was admitted to the hospital with mantle cell lymphoma (MCL) and colon cancer and aimed to explore measures to reduce missed diagnosis. Based on the data, the investigation of the related literatures, colonoscopy examination, and abdominal computed tomography (CT) scan were conducted for the detection of colon cancer. Following this, a precise diagnosis of MCL was
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32

Khorobrykh, T. V., V. G. Agadzhanov, R. E. Salikhov, N. P. Mishchenko, and T. R. Gogokhiya. "Multiple primary synchronous colon cancers in patients with advance gastric cancer." Khirurgiya. Zhurnal im. N.I. Pirogova, no. 3 (2021): 62. http://dx.doi.org/10.17116/hirurgia202103162.

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Soldatkina, N. V., O. I. Kit, Yu A. Gevorkyan, and A. G. Milakin. "Multiple primary colorectal cancer: Clinical aspects." Terapevticheskii arkhiv 88, no. 8 (2016): 53–58. http://dx.doi.org/10.17116/terarkh201688853-58.

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Aim. To define some clinical characteristics of synchronous and metachronous colorectal cancer (CRC). Materials and methods. The investigation was concerned with the data of 150 patients with T1—4N0—2M0—1 multiple primary CRC. The clinical, biological, and morphological characteristics of synchronous and metachronous tumors were analyzed. Results. Multiple primary tumors were 6.01% of all the cases of CRC. There was a preponderance of synchronous CRC (63.75%) with the tumor localized in the sigmoid colon and rectum. In women, synchronous colorectal tumors were more often concurrent with breast
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Serio, Gabriella, Federica Pezzuto, Francesco Fortarezza, et al. "Mesothelioma and Colorectal Cancer: Report of Four Cases with Synchronous and Metachronous Presentation." International Journal of Molecular Sciences 23, no. 5 (2022): 2630. http://dx.doi.org/10.3390/ijms23052630.

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There is evidence that asbestos could play a role in the carcinogenesis of digestive cancers. The presence of asbestos fibres in histological samples from gastric, biliary, colon cancers has been reported, but the mechanism is still controversial. It has been hypothesised that asbestos reaches these sites, especially through contaminated water; however, some experimental studies have shown that the inhaled fibres are mobile, so they can migrate to many organs, directly or via blood and lymph flow. We report four unusual cases of colorectal cancers in patients with a long history of asbestos ex
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Yajima, Kazuhito, Shin-Ichi Kosugi, Yosuke Kano, et al. "Two-Step Laparoscopic Surgery for a Patient with Synchronous Double Cancer of the Colon and Stomach Accompanied by Severe Chronic Obstructive Pulmonary Disease." Case Reports in Surgery 2013 (2013): 1–6. http://dx.doi.org/10.1155/2013/246515.

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Laparoscopic treatment strategies for synchronous intra-abdominal malignancies have not yet been standardized. We report a successful case of two-step laparoscopic surgery for synchronous double cancer of the colon and stomach accompanied by severe chronic obstructive pulmonary disease (COPD). A 66-year-old man with COPD was diagnosed as having advanced colon cancer and early gastric cancer. On admission, he could not go upstairs (Grade III according to the Hugh-Jones classification) and his forced expiratory volume in 1 second was 600 mL (35.9%). The patient initially underwent laparoscopy-as
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Lytvynenko, O. O., B. V. Sorokin, I. V. Halchak, O. P. Lishchenko, and V. O. Demianov. "SYNCHRONOUS COLON CANCER ASSOCIATED WITH IDIOPATHIC THROMBOCYTOPENIC PURPURA. CLINICAL CASE." Проблеми радіаційної медицини та радіобіології = Problems of Radiation Medicine and Radiobiology 29 (2024): 465–72. https://doi.org/10.33145/2304-8336-2024-29-465-472.

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We present а rare clinical case of successful surgical treatment – combined left-sided hemicolectomy and cecal resection for colon cancer of two locations in a patient with idiopathic thrombocytopenic purpura, which, in our opinion, is due to radiation exposure is presented. It is shown that the biological effects of long-term ionizing radiation on critical organs can have a diverse nature both in terms of the time of occurrence and in their structure, which requires an individual approach, the involvement of related specialists and the necessary medical preoperative preparation for precise pl
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37

Emiloju, Oluwadunni E., Bahar Saberzadeh-Ardestani, and Frank A. Sinicrope. "Synchronous Neoplasia Rates at Colonoscopic Diagnosis of Early-Onset vs Average-Onset Colorectal Cancer." JAMA Network Open 6, no. 7 (2023): e2324038. http://dx.doi.org/10.1001/jamanetworkopen.2023.24038.

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ImportanceThe incidence of early-onset colorectal cancer (CRC) (age, &amp;amp;lt;50 years) continues to increase globally within high-income countries.ObjectiveTo examine and compare rates of synchronous neoplasia found in patients at colonoscopic diagnosis of early-onset CRC with rates found at diagnosis of average-onset CRC.Design, Setting, and ParticipantsIn this multisite retrospective and cross-sectional study conducted at Mayo Clinic sites and in the Mayo Clinic Health System from January 1, 2012, to December 31, 2022, 150 randomly selected patients with early-onset CRC were identified f
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Emiloju, Oluwadunni Eunice, Bahar Saberzadeh Ardestani, and Frank A. Sinicrope. "Comparison of synchronous neoplasms at colonoscopic diagnosis of early-onset versus average-onset colorectal cancer." Journal of Clinical Oncology 41, no. 16_suppl (2023): 3623. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.3623.

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3623 Background: Colorectal cancer (CRC) incidence has steadily increased in adults younger than 50 years (EO-CRC) since the 1990s, with a predominance in the left colon and rectum. Precursor lesions of CRCs are adenomas, including advanced adenomas, and sessile serrated polyps. Given that neoplastic development is age-related, we hypothesized that patients with early-onset CRC (EO-CRC) may have fewer adenomas compared to patients with average-onset CRC (AO-CRC) at diagnosis. Methods: We performed a retrospective review of electronic health records at Mayo Clinic or Mayo Health System [2012 to
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ASANO, Toshimichi, Toshifumi SHIMADA, Shunichi OKUSHIBA, Satoshi KONDO, and Hiroyuki KATO. "Two cases of synchronous overian metastasis from colon cancer." Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 64, no. 2 (2003): 408–12. http://dx.doi.org/10.3919/jjsa.64.408.

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Geiger, Timothy M., Zachary D. Tebb, Erika Sato, Brent W. Miedema, and Ziad T. Awad. "Laparoscopic Resection of Colon Cancer and Synchronous Liver Metastasis." Journal of Laparoendoscopic & Advanced Surgical Techniques 16, no. 1 (2006): 51–53. http://dx.doi.org/10.1089/lap.2006.16.51.

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41

Higgins, L., I. Robertson, W. Khan, and K. Barry. "Synchronous breast and colon cancer: factors determining treatment strategy." Case Reports 2013, jul10 1 (2013): bcr2013009450. http://dx.doi.org/10.1136/bcr-2013-009450.

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42

Glover, Caleb, Claire Russell, Ali Rida, et al. "Genetic Predisposition and Multifocal Cancer: A Complex Case of Lynch Syndrome." ACG Case Reports Journal 12, no. 6 (2025): e01718. https://doi.org/10.14309/crj.0000000000001718.

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ABSTRACT This case report describes the complex presentation and management of a 35-year-old man with synchronous malignancies: A well-differentiated grade 2 neuroendocrine tumor of the pancreas metastasized to the liver and bone, and invasive adenocarcinoma of the sigmoid colon. Strong clinical suspicion for Lynch syndrome arose due to the patient's family history and the loss of MSH1 and PMS2 protein expression in the colon adenocarcinoma. The patient presented with hypoglycemia, abdominal pain, and diarrhea. A multidisciplinary approach confirmed the diagnoses, including imaging studies (co
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Manalu, Ester Puti Andyni, and Gunadi Petrus. "Synchronous colorectal cancer: a case report." International Surgery Journal 10, no. 10 (2023): 1680–83. http://dx.doi.org/10.18203/2349-2902.isj20232994.

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Synchronous colorectal cancer (CRCs) refers to more than 1 primary CRCs detected in a single patient simultaneously or within 6 months of the initial diagnosis. A 76-year-old men presented with persistent constipation since 1 month ago. Abdominal computed tomography (CT) showed an irregular mass in the right lower middle abdomen. Intraoperatively, the synchronous CRCs was found, therefore a subtotal colectomy was performed and the diagnosis was confirmed by histopathological examination. Synchronous CRCs is relatively rare. The CT can detect tumor, node, and metastasis (TNM) staging of colon c
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Kim, Heung Up, In Ho Jeong, Hyun Wook Kang, Ji Hun Kim, and Hyoung Suk Ko. "Colon Type Adenocarcinoma of Appendiceal Orifice with Synchronous Colon Cancer and Appendiceal Mucocele." Journal of the Korean Surgical Society 76, no. 6 (2009): 398. http://dx.doi.org/10.4174/jkss.2009.76.6.398.

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Stadler, Zsofia Kinga, Jinru Shia, Karyn A. Goodman, et al. "Characterization of rectal cancer in patients with Lynch syndrome." Journal of Clinical Oncology 31, no. 4_suppl (2013): 350. http://dx.doi.org/10.1200/jco.2013.31.4_suppl.350.

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350 Background: Lynch syndrome (LS), resulting from a germline mutation in a DNA mismatch repair (MMR) gene, is associated with ~70% lifetime colorectal cancer (CRC) risk. Although LS-associated colon cancer is associated with both favorable prognosis and lack of efficacy to 5-fluorouracil, clinical features of LS-associated rectal cancer (RC) have not been characterized. Methods: Clinical genetics database review (1998–2012) identified all probands with CRC and a deleterious germline mutation in a MMR gene (MLH1, MSH2, MSH6, PMS2) diagnostic of LS. Probands without identifiable mutations or v
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Ignatov, I. S., V. V. Balaban, E. A. Bezrukov, A. V. Nikishina, M. He, and P. V. Tsarkov. "Outcomes of Surgical Treatment of Multiple Primary Colorectal and Prostate Cancer." Russian Journal of Gastroenterology, Hepatology, Coloproctology 34, no. 6 (2024): 49–66. https://doi.org/10.22416/1382-4376-2024-34-6-49-66.

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Aim: to evaluate the outcomes of surgical treatment of patients with multiple primary cancer of the colon and prostate.Materials and methods. An observational retrospective study was conducted at the Clinic of Coloproctology and Minimally Invasive Surgery (I.M. Sechenov First Moscow State Medical University). A total of 3,640 protocols of the preoperative multidisciplinary team were studied from July 2018 to April 2024. The inclusion criterion was the diagnosis of multiple colorectal and prostate cancer. The medical documentation was collected in the database and analyzed.Results. The study in
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Suh, Byoung Jo. "Synchronous and Metachronous Colon Cancers in Patients with Gastric Cancer: Report of 2 Cases." Case Reports in Oncology 9, no. 3 (2016): 752–59. http://dx.doi.org/10.1159/000452831.

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Colorectal cancer is the most common synchronous or metachronous cancer in patients with gastric cancer. I report two cases of synchronous and metachronous colon cancer with gastric cancer. Case 1: A 70-year-old man was admitted to our hospital for the treatment of gastric cancer, which had been diagnosed during esophagogastroduodenoscopy (EGD) screening. The recommended preoperative testing was colonofiberscopy (CFS). The CFS revealed a 3-cm ulcerofungating mass, located 20 cm from the anal verge. The pathological report showed a well-differentiated adenocarcinoma. Consequently, we performed
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Luo, Xin-Xin, Yu-Xuan Du, Qi-Qing Zhang, et al. "Cetuximab combined with chemotherapy for simultaneous esophageal squamous cell carcinoma and colon adenocarcinoma: A case report." World Journal of Clinical Cases 12, no. 15 (2024): 2649–54. http://dx.doi.org/10.12998/wjcc.v12.i15.2649.

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BACKGROUND Multiple primary carcinomas (MPCs) are defined as two or more independent primary cancers that occur simultaneously or sequentially in the same individual. Synchronous MPCs are rarer than solitary cancers or metachronous MPCs. Accurate diagnoses of synchronous MPCs and the choice of treatment are critical for successful outcomes in these cases. CASE SUMMARY A 64-year-old patient presented with dysphagia, without obvious cause. A diagnosis of synchronous esophageal squamous cell carcinoma and colon adenocarcinoma with liver metastasis was confirmed based on examination and laboratory
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Montalvo-Javé, Eduardo Esteban, Billy Jiménez Bobadilla, Mariana Espejel Deloiza, Irving Hugo Aguilar Preciado, Luis Fernando Negrete Cervantes, and Héctor Diliz-Pérez. "Synchronous Resection of Colon Adenocarcinoma and Bisegmentectomy of Liver Metastases." Case Reports in Gastroenterology 13, no. 2 (2019): 238–44. http://dx.doi.org/10.1159/000499423.

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Colorectal cancer is one of the main neoplasms worldwide; at the time of diagnosis about 25% of cases already have an advanced stage with the presence of metastases. A 58-year-old female presented with nausea, vomiting, and black stools and diffuse abdominal pain associated with 7% weight loss. She was referred to our hospital with signs of digestive tract bleeding and anemic syndrome. Panendoscopy revealed body and fundus gastropathy and presence of Helicobacter pylori, and colonoscopy showed a neoplastic lesion at the ascending colon level. A synchronous resection was performed in a single s
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Yeh, Chia-Lu, and Yen-Kung Chen. "Utility of FDG Metabolism to Differentiate Synchronous Metastatic Liver Lesions From Synchronous Colon Cancer." Clinical Nuclear Medicine 35, no. 1 (2010): 44–46. http://dx.doi.org/10.1097/rlu.0b013e3181c361c4.

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