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1

Belinga, Etienne, Isidore Tompeen, Claude Cyrille Noa Ndoua, Junie Metogo Ntsama, Sandrine Mendibi, and Jean Marie Kasia. "Diagnostic, therapeutic and prognostic aspects of uterine synechiae managed by hysteroscopy in the gyanecological endoscopic surgery and human reproductive teaching hospital." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 1 (December 25, 2017): 56. http://dx.doi.org/10.18203/2320-1770.ijrcog20175833.

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Background: Uterine synechiae refers to a total or partial union of the inner walls of the uterus resulting from endometrial trauma. It is a cause of reproductive failure. Until now, synechia was not optimally treated and has remained understudied in Cameroon. Objective of present study was to Evaluate the diagnostic, therapeutic and prognostic aspects of uterine synechiae treated by hysteroscopy.Methods: We conducted a descriptive cross-sectional study with an analytical component from January 1st 2015 to July 31st 2017 at Yaounde. All patients diagnosed with uterine synechiae and treated with hysteroscopy were our sample. Sampling was consecutive. The chi-square test was used for the comparison of qualitative variables and Fisher's test for ANOVA variance analysis. The comparison of the averages was made by the Student's test. P-value less than 0.05 was considered as statistically significant.Results: Hysteroscopies were indicated for uterine synechiae in 14.50%. Nulliparous were 56.67%. A history of curettage/aspiration was present in 66.66%. All of the patients had a form of infertility and 83.33% had menstrual disorders. Hysterosalpingography showed a better sensitivity (88%). After hysteroscopic treatment, 63.30% had a complete anatomical restitution. There is a significant correlation between the stage of severity of synechia and anatomical restitution (p=0.008; Spearman correlation coefficient=-0.477).Conclusions: Uterine synechiae represent one-sixth of all indications for hysteroscopy and present clinically as menstrual disorder associated with infertility. A past history of uterine curettage is common. Hysterosalpingography has a better preoperative diagnostic sensitivity. Hysteroscopy allows optimal treatment.
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2

Silveira, Débora Filardi, Carlos Alberto Rodrigues Junior, Fellipe Camargo Ferreira Dias, Camila Filardi Silveira, and Caroline Filardi Silveira. "Avaliação ultrassonográfica no espessamento endometrial: revisão de literatura." Revista de Patologia do Tocantins 4, no. 4 (November 29, 2017): 60. http://dx.doi.org/10.20873/uft.2446-6492.2017v4n4p60.

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Introdução: A avaliação ecográfica do endométrio permite a análise minuciosa da mucosa uterina na prática clínica ginecológica, com o intuito de auxiliar no manejo das patologias endometriais. Neste artigo, fazemos uma revisão narrativa para avaliar o real papel da ecografia pélvica na visualização das doenças endometriais. As alterações uterinas, como pólipos, miomas, sinéquias uterinas, hiperplasia e câncer endometrial são morbidades frequentes na população feminina, tanto nas pacientes em idade reprodutiva como nas que estão na pós-menopausa. Os métodos de avaliação endometrial têm obtido diversos avanços nos tempos atuais, sendo o ultrassom transvaginal o método de escolha para investigação inicial das doenças endometriais, tanto nas pacientes com sangramento genital, quanto nas mulheres assintomáticas principalmente na pós-menopausa. Conclusão: A ecografia é o exame primordial e elementar na investigação de pacientes com sangramento uterino anormal ou sob suspeita de outras doenças que alteram o padrão endometrial, conduzindo o prognóstico do quadro investigado. Palavras-chave: Ultrassonografia, Doenças Uterinas, Endométrio. ABSTRACT Introduction: The ultrasound evaluation of the endometrium allows a detailed analysis of the uterine mucosa in gynecological clinical practice, in order to assist in the management of endometrial pathologies. In this article, we make a narrative review to evaluate the real role of pelvic ultrasound in the visualization of endometrial diseases. Uterine changes such as polyps, fibroids, uterine synechia, hyperplasia, and endometrial cancer are frequent morbidities in the female population, both in postmenopausal and post-reproductive age patients. Methods of endometrial evaluation have achieved several advances in the present times, with transvaginal ultrasound being the method of choice for the initial investigation of endometrial diseases, both in patients with genital bleeding and in asymptomatic women, especially postmenopausal women. Conclusion: Ultrasonography is the primary and elemental examination in the investigation of patients with abnormal uterine bleeding or under suspicion of other diseases that alter the endometrial pattern, leading to the prognosis of the investigated condition. Keywords: Ultrasonography, Uterine Diseases, Endometrium.
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3

Tuuli, Methodius G., Anthony Shanks, Lisa Bernhard, Anthony O. Odibo, George A. Macones, and Alison Cahill. "Uterine Synechiae and Pregnancy Complications." Obstetrics & Gynecology 119, no. 4 (April 2012): 810–14. http://dx.doi.org/10.1097/aog.0b013e31824be28a.

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4

Rathat, Gauthier, Phi Do Trinh, Grégoire Mercier, Lionel Reyftmann, Clotilde Dechanet, Pierre Boulot, and Pierre Ludovic Giacalone. "Synechia after uterine compression sutures." Fertility and Sterility 95, no. 1 (January 2011): 405–9. http://dx.doi.org/10.1016/j.fertnstert.2010.08.055.

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5

Nakhuda, Gary S., Nataki C. Douglas, and Mark V. Sauer. "Clinically Significant Uterine Synechiae Caused by Transmural Uterine Incisions." Journal of Gynecologic Surgery 21, no. 2 (June 2005): 95–98. http://dx.doi.org/10.1089/gyn.2005.21.95.

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6

Marasinghe, JP, and N. Saravanabhava. "Risk of synechiae following uterine compression sutures." BJOG: An International Journal of Obstetrics & Gynaecology 118, no. 8 (June 10, 2011): 1020–21. http://dx.doi.org/10.1111/j.1471-0528.2011.03007.x.

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7

Poujade, O., and D. Luton. "Risk of synechiae following uterine compression sutures." BJOG: An International Journal of Obstetrics & Gynaecology 118, no. 8 (June 10, 2011): 1021–22. http://dx.doi.org/10.1111/j.1471-0528.2011.03008.x.

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8

Takashi, M. "Classification of hysteroscopic adhesiolysis for uterine synechiae." Journal of the American Association of Gynecologic Laparoscopists 9, no. 3 (August 2002): S75. http://dx.doi.org/10.1016/s1074-3804(02)80247-x.

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9

Pande, Benudhar, Soumyashree Padhan, and Pranati Pradhan. "Uterine Anomalies in Infertility - An Evaluation by Diagnostic Hysterolaparoscopy." Journal of Evidence Based Medicine and Healthcare 7, no. 48 (November 30, 2020): 2831–35. http://dx.doi.org/10.18410/jebmh/2020/580.

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BACKGROUND About 10 - 15 % of reproductive age couples are affected by infertility.1 According to WHO 60 - 80 million couples currently suffer from infertility.2 Prevalence of infertility is rapidly increasing globally.3 Uterine factors of infertility include uterine anomalies, fibroid uterus, synechiae, Asherman’s syndrome, and failure of implantation without any known primary causes. Congenital uterine malformations are seen in 10 % cases of infertile women. We wanted to evaluate the anomalies of uterus in case of primary and secondary infertility by DHL (diagnostic hysterolaperoscopy). METHODS This is a hospital-based, observational study, conducted in the Department of Obstetrics and Gynaecology, VIMSAR, Burla, from November 2017 to October 2019. Diagnostic hysterolaparoscopy was done in 100 infertility cases. RESULTS In our study, uterine anomaly i.e. septate uterus was the most common hysteroscopic abnormaly found in 23 cases followed by submucous fibroid, polyp, synechiae and bicornuate uterus. CONCLUSIONS With proper selection of cases, and when done by skilled surgeon, can be considered as standard day care procedure for female infertility evaluation. KEYWORDS Infertility, Uterine Anomalies, Diagnostic Hysterolaparoscopy
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10

Galamb, Ádám, Boglárka Pethő, Dávid Fekete, Győző Petrányi, and Attila Pajor. "A méhüreg anatómiai rendellenességei habituális vetélőkben." Orvosi Hetilap 156, no. 27 (July 2015): 1081–84. http://dx.doi.org/10.1556/650.2015.30136.

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Introduction: One percent of couples trying to have children are affected by recurrent miscarriage. These pregnancy losses have different pathogenetic (genetic, endocrine, anatomic, immunologic, microbiologic, haematologic and andrologic) backgrounds, but recurrent miscarriage remains unexplained in more than half of the affected couples. Aim: To explore risk factors for recurrent pregnancy loss the authors studied the incidence of anatomic disorders of the uterine cavity occur in Hungarian women with recurrent miscarriage. Method: Medical records of 152 patients with recurrent miscarriage were analyzed retrospectively. In order to explore disorders of the uterine cavity hysteroscopy or 3-dimensional sonography in 132 women, hysterosalpingography in 16 and hysterosalpingo-sonography in 4 patients were used. Results: Incidence of anomalies in the uterine cavity was found in women with recurrent miscarriage to be 15.8%. A variety of the uterine anomalies was found including uterine septum in 6.5%, endometrial polyp in 2.6%, arcuate and bicornuate uteri both in 2% and 2%, submucosal myoma in 1.3 %, and intrauterine synechiae in 1.3%. Conclusions: These findings suggest that morphologic disorder of the uterine cavity is frequent in Hungarian women with recurrent miscarriage. Therefore, assessment of the uterine anatomy is recommended in such patients. Orv. Hetil., 2015, 156(27), 1081–1084.
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11

Salzani, Adriana, Daniela Angerame Yela, José Roberto Erbolato Gabiatti, Aloísio José Bedone, and Ilza Maria Urbano Monteiro. "Prevalence of uterine synechia after abortion evacuation curettage." Sao Paulo Medical Journal 125, no. 5 (September 2007): 261–64. http://dx.doi.org/10.1590/s1516-31802007000500002.

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CONTEXT AND OBJECTIVE: Intrauterine adhesion (IUA) is a possible complication of uterine curettage following abortion. Because IUA is an important cause of infertility, some investigators have been advocating its inclusion in the routine investigational workup after every abortion curettage procedure. The aim of this study was to evaluate the uterine cavity of patients subjected to abortion curettage, in order to ascertain the prevalence of IUA and its association with social and clinical factors. DESIGN AND SETTING: This was a cross-sectional study at the Human Reproduction Unit, Department of Obstetrics and Gynecology, Universidade Estadual de Campinas (Unicamp). METHODS: A total of 109 women were enrolled. The investigators searched the records of Unicamp's hospital for patients who had been subjected to uterine curettage following abortion. The hysteroscopy was performed 3 to 12 months after the curettage. The correlations between patients' characteristics and the prevalence of IUA were assessed by means of chi-squared and Fisher's exact test calculations. RESULTS: The prevalence of IUA was 37.6%. The number of previous abortions and curettage procedures did not correlate with the presence of IUA. Most of the women (56.1%) presented IUA grade I. CONCLUSIONS: In the present study, 37.6% of the women subjected to curettage following abortion had IUA, which was mostly mucous and grade I. None of the demographic and clinic characteristics evaluated were found to be associated with IUA. From this study, there is no firm evidence to justify carrying out routine diagnostic hysteroscopy following abortion evacuation.
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12

Tanaka, Hirokazu, and Megumi Ito. "HDlive Silhouette for Antenatal Diagnosis of Uterine Synechia." Donald School Journal of Ultrasound in Obstetrics and Gynecology 12, no. 4 (2018): 249–51. http://dx.doi.org/10.5005/jp-journals-10009-1572.

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13

Hill, L. M., and A. Mills. "Umbilical cord prolapse through a transverse uterine synechia." Journal of Ultrasound in Medicine 11, no. 11 (November 1992): 617–18. http://dx.doi.org/10.7863/jum.1992.11.11.617.

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14

Mukul, Liberato V., and James G. Linn. "Pregnancy Complicated by Uterine Synechiae After Endometrial Ablation." Obstetrics & Gynecology 105, Supplement (May 2005): 1179–82. http://dx.doi.org/10.1097/01.aog.0000143260.27012.92.

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15

Wu, Hsin-hung, and Guang-Perng Yeh. "Uterine Cavity Synechiae After Hemostatic Square Suturing Technique." Obstetrics & Gynecology 105, Supplement (May 2005): 1176–78. http://dx.doi.org/10.1097/01.aog.0000159978.26472.a4.

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Sato, Miki, Kenji Kanenishi, Megumi Ito, Hirokazu Tanaka, Mikihiko Takemoto, and Toshiyuki Hata. "Antenatal 3-D sonographic features of uterine synechia." Journal of Obstetrics and Gynaecology Research 39, no. 1 (August 13, 2012): 395–98. http://dx.doi.org/10.1111/j.1447-0756.2012.01950.x.

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17

Ibrahim, Moustafa I., Tarek A. Raafat, Mohamed I. Ellaithy, and Rehab T. Aly. "Risk of postpartum uterine synechiae following uterine compression suturing during postpartum haemorrhage." Australian and New Zealand Journal of Obstetrics and Gynaecology 53, no. 1 (November 20, 2012): 37–45. http://dx.doi.org/10.1111/ajo.12017.

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18

Martynov, Sergey A., Leyla V. Adamyan, Alek S. Arakelyan, Tatyana A. Fyodorova, and Oksana A. Bystrykh. "Possibilities of using platelet-rich autoplasm in the complex treatment of patients with intrauterine synechiae." Gynecology 23, no. 3 (August 13, 2021): 250–54. http://dx.doi.org/10.26442/20795696.2021.3.200878.

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Aim. To increase the effectiveness of complex treatment of women with intrauterine synechiae (IS) through intrauterine administration of platelet-rich plasma (PRP). Materials and methods. The authors studied the complex treatment results of 60 women with second and third degree intrauterine synechiae: 20 patients in the active treatment group, after hysteroscopic destruction of intrauterine synechiae, underwent intraoperative subendometrial administration of PRP followed by irrigating the uterine cavity with PRP on the 2nd and 3rd days after the operation, along with complex postoperative treatment (antibacteria and cyclic hormone therapy, physiotherapy); 40 patients in the comparison group underwent only complex postoperative treatment without PRP administration. The authors conducted comparative assessments of menstrual function, endometrial thickness and uterine cavity during check-up hysteroscopy procedure. Results. Two months after the treatment, a statistically more significant increase in the thickness of endometrial tissue was found with the use of PRP compared with patients treated without PRP (p=0.03 and 0.04). Statistically more significant changes in the state of the uterine cavity were revealed when using PRP in the group of patients with the second-degree process severity (p=0.00005), while in patients with the third-degree process severity there were no statistically significant differences identified depending on the method of treatment used. The authors confirm high safety and reliability of the method as well as no adverse reactions to parenteral and intracavitary administration of autologous PRP. Conclusion. The study confirmed applicability and prospects of using PRP as a stage in complex treatment of IS patients.
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Kaur, Navneet, Ruby Bhatia, Paramjit Kaur, and Surinder K. Bhopal. "Hysteroscopic evaluation in infertility and abnormal uterine bleeding." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 2 (January 23, 2018): 612. http://dx.doi.org/10.18203/2320-1770.ijrcog20180181.

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Background: Hysteroscopy an endoscopic procedure for visualization of uterine cavity may be extensively used in both primary and secondary infertility and abnormal uterine bleeding for evaluating intrauterine pathology. The objectives of this study were to visualize and identity intrauterine pathology in both primary and secondary infertility and abnormal uterine bleeding (AUB) by hysteroscopic evaluation and to perform hysteroscopic guided therapeutic procedures like endometrial currettage, polypectomy, adhesiolysis.Methods: Hysteroscopic evaluation of uterine cavity for any intrauterine pathology in AUB and Infertility. Adhesiolysis, polypectomy, endometrial biopsy misplaced copper T removal were carried out under hysteroscopic vision.Results: Intrauterine synechia in 20.51%, Submucous fibroid in 5.13%, bicornuate uterus, endometrial hyperplasia and endometrial polyp were seen in 2.56% patient each were detected in infertility group while 81.95% cases with AUB had abnormal intrauterine pathology commonest being endometrial hyperplasia in 33.33% followed by endometrial polyps in 23.81% cases, submucous fibroid and misplaced copper T in 9.52% each and intrauterine synechia in 4.76% patient. Endometrial biopsy and polypectomy was done in 23.80% each with AUB, misplaced copper T removal in 9.52% and adhesiolysis in 4.76% patient with AUB.Conclusions: Hysteroscopy remains gold standard for evaluating intrauterine lesions in abnormal uterine bleeding and infertility. A safe, simple minimally invasive procedure not only diagnostic but therapeutic modality for adhesiolysis, endometrial biopsy/curettage, polypectomy, misplaced copper T removal under direct vision with minimal complication within reach of every Gynaecologist thereby reducing burden of major surgical intervention.
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Gurgan, T., H. Yarali, B. Urman, V. Dagli, and L. Dogan. "Uterine rupture following hysteroscopic lysis of synechiae due to tuberculosis and uterine perforation." Human Reproduction 11, no. 2 (February 1, 1996): 291–93. http://dx.doi.org/10.1093/humrep/11.2.291.

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Cho, Hyun Jin. "An intrauterine fetal death due to horizontal uterine synechia." Taiwanese Journal of Obstetrics and Gynecology 56, no. 3 (June 2017): 406–7. http://dx.doi.org/10.1016/j.tjog.2016.12.009.

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22

Burton, Elizabeth. "Serial Evaluations of Perinatal Uterine Synechiae Versus Amniotic Bands." Journal of Diagnostic Medical Sonography 20, no. 1 (January 2004): 51–56. http://dx.doi.org/10.1177/8756479303258492.

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23

Mashima, Masato, Hirokazu Tanaka, Megumi Ishibashi, Tomihiro Katayama, and Toshiyuki Hata. "HDlive imaging of vertical, bridging uterine synechia during pregnancy." Journal of Medical Ultrasonics 41, no. 4 (June 5, 2014): 521–24. http://dx.doi.org/10.1007/s10396-014-0549-5.

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24

Devabhaktuni, Pratibha, Padmaja Allani, Suneetha Komatlapalli, and Rekha Rani Ksheerasagara. "Hysteroscopy in one hundred cases of postmenopausal uterine bleeding, in the detection of uterine cancer and atypical endometrial hyperplasia." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 6 (May 27, 2020): 2253. http://dx.doi.org/10.18203/2320-1770.ijrcog20202084.

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Background: Evaluation was done in 100 women presenting with postmenopausal bleeding, (PMB), to discuss the utility of hysteroscopy combined guided endometrial curettage in the diagnosis of uterine cancer and endometrial hyperplasia, and, treat benign lesions, like polyps, synechiae at the same sitting. At MGMH during the years, 2002 to 2006, there were 57 women, and at care, 40 women with PMB during 2011 to 2013, and three in a nursing home, Hyderabad, were investigated.Methods: Evaluation was done in 100 women presenting with PMB by hysteroscopy and curettage to diagnose the cause of PMB and benign lesions like polyps, synechiae were managed by operative hysteroscopy. Bettocchi 5 mm hysteroscope, monopolar instruments and glycine was used for excision of polyps.Results: In one hundred women with PMB, 19% had cancer. Endometrial adenocarcinoma in 14, endocervical carcinoma in 2, uterine carcinosarcoma in 3 cases. All 3 cases of uterine carcinosarcoma on hysteroscopy were large polyps measuring 5×5-6 cm size. Atypical hyperplasia endometrium in 7% and simple hyperplasia in 17%, was reported on histopathology, in cases with hyperplastic endometrium on hysteroscopy. Benign polyps in 41% were managed at the same sitting by operative hysteroscopy.Conclusions: Women with postmenopausal bleeding must have USG, trans vaginal sonography (TVS), endometrial thickness (ET) measurement, preferably endometrial echo complex (EEC). In women with PMB, the risk of uterine cancer would be 19%, i.e., 1 out of 5 women. Atypical hyperplasia in 7%. Hysteroscopy guided curettage, with histopathology, is the gold standard protocol in cases of PMB.
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Ball, R. H., S. E. Buchmeier, and M. Longnecker. "Clinical significance of sonographically detected uterine synechiae in pregnant patients." Journal of Ultrasound in Medicine 16, no. 7 (July 1997): 465–69. http://dx.doi.org/10.7863/jum.1997.16.7.465.

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Bäumler, M., J. M. Faure, A. Couture, S. Flunker, and P. Boulot. "Prenatal 3D ultrasound and MRI assessment of horizontal uterine synechia." Prenatal Diagnosis 28, no. 9 (September 2008): 874–75. http://dx.doi.org/10.1002/pd.2078.

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Roge, P., C. D'Ercole, L. Cravello, L. Boubli, and B. Blanc. "Hysteroscopic management of uterine synechiae: A series of 102 observations." European Journal of Obstetrics & Gynecology and Reproductive Biology 65, no. 2 (April 1996): 189–93. http://dx.doi.org/10.1016/0301-2115(95)02342-9.

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Roman, Horace, Loïc Sentilhes, Michel Cingotti, Eric Verspyck, and Loïc Marpeau. "Uterine devascularization and subsequent major intrauterine synechiae and ovarian failure." Fertility and Sterility 83, no. 3 (March 2005): 755–57. http://dx.doi.org/10.1016/j.fertnstert.2004.07.975.

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29

Molotkov, Arseniy S., Eduard N. Popov, Dmitriy S. Sudakov, Tatyana A. Aivazyan, Lyudmila A. Alexandrova, and Yulia R. Dymarskaya. "Experience of intrauterine application of anti-adhesive gel based on hyaluronic acid in the prevention of Asherman's syndrome in patients with the pathology of the uterine cavity and severe forms of endometriosis." Journal of obstetrics and women's diseases 66, no. 6 (December 15, 2017): 12–19. http://dx.doi.org/10.17816/jowd66612-19.

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Introduction. One of the leading problems of modern reproductive surgery is treatment of adhesive disease, and in turn, prevention of intrauterine adhesions after intrauterine interventions is of particular interest. Purpose: to evaluate the effectiveness and safety of anti-adhesive gel “Antiadgesin” for intrauterine use in patients with a combination of pathology of the uterine cavity and severe forms of endometriosis. Materials and methods. The study included 24 patients aged 23 to 39 years with a combination of pathology of the uterine cavity and severe forms of genital endometriosis. The main group consisted of 12 patients to whom the anti-adhesive gel “Antiadhesin” was applied at the end of the laparoscopic and hysteroscopic stages on the region of the ovaries, pelvic peritoneum in the areas of separation of the adhesions, and also inside the uterine cavity. The comparison group included 12 patients who received 0.9% sodium chloride solution (5 ml) on the surgical area. Patients of both groups underwent treatment with gonadotropin-releasing hormone agonists (GnRH-a) 3.75 mg for 4 months after the operation. We performed gynecological ultrasound 4 weeks after operation, 4 weeks after the last injection of GnRH-a, and after the first menstrual bleeding. Assessment of the state of the uterine cavity, diagnosis of intrauterine synechia was performed by hydrosonography. Results. The duration of the operation, the amount of intraoperative blood loss did not differ significantly between the groups. In all patients, no complications of the postoperative period, no allergic or inflammatory reactions associated with the use of “Antiadhesin” were detected. The duration the uterine bleeding after the operation did not differ significantly between the groups. In 2 patients of the comparison group hydrosonography confirmed the adhesive pathology of the uterine cavity. In the main group there were not identified any signs of intrauterine adhesions by ultrasound. Within 12 months after the treatment, pregnancy occurred in 50% of the patients in the main group and in 33.3% of the patients in the comparison group. Conclusion. The results of the study showed that the introduction of the anti-adhesive gel “Antiadgesin” in the uterine cavity after hysteroresectoscopy is a safe and effective method for preventing the formation of intrauterine synechia.
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Schoot, B. C. "“Extra Amniotic Band Syndrome” – Uterine Synechiae and Development of Early Pregnancy." Journal of Minimally Invasive Gynecology 16, no. 6 (November 2009): S32. http://dx.doi.org/10.1016/j.jmig.2009.08.118.

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Deering, S. "Intrauterine head entrapment of a second twin by a uterine synechia." Obstetrics & Gynecology 102, no. 4 (October 2003): 693–95. http://dx.doi.org/10.1016/s0029-7844(03)00678-1.

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Dickey, Kevin W. "Cervical Stenosis and Uterine Synechiae: Evaluation and Treatment with Interventional Methods." Seminars in Interventional Radiology Volume 17, Number 03 (2000): 309–14. http://dx.doi.org/10.1055/s-2000-9432.

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Deering, Shad H., Jessica Heller, Craig Winkel, and Helain J. Landy. "Intrauterine Head Entrapment of a Second Twin by a Uterine Synechia." Obstetrics & Gynecology 102, no. 4 (October 2003): 693–95. http://dx.doi.org/10.1097/00006250-200310000-00009.

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34

Gabidullina, R. I., S. E. Savel’ev, N. A. Gabitov, O. N. Mikhaylova, L. I. Sirmatova, and N. R. Nazmutdinova. "Evacuation of embryo in the presence of intrauterine adhesions." Kazan medical journal 97, no. 6 (December 15, 2016): 967–70. http://dx.doi.org/10.17750/kmj2016-967.

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Asherman syndrome is a controversial topic in gynecology without a clear consensus for treatment. This pathology is characterized by adhesions in the uterine cavity. The main cause of this disorder is injuries to the gravid uterus especially in abortion, during postnatal period or after missed miscarriage. Menstrual disorders and infertility are characteristic clinical features of Asherman syndrome. Pregnancy may be complicated with premature labor, placenta previa and placenta accreta. Introduction of hysteroscopy has changed diagnosis and management of intrauterine synechiae and it is therefore considered the most valuable tool nowadays. Preferred treatment method is hysteroscopic lysis of adhesions combined with estrogens. A clinical case of asymptomatic Asherman syndrome in a 29 year old female is presented in the article. Bipolar hysteroscopic resection of synechiae in combination with curettage was proved to be an effective and safe method of treatment.
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Tchounzou, R., M. Ngono, B. Moifo, and R. Enow Mbu. "Treatment of uterine synechiae without hysteroscopy in a semiurban setting in Cameroon." Médecine et Santé Tropicales 24, no. 3 (July 2014): 263–65. http://dx.doi.org/10.1684/mst.2014.0340.

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Fernandez, Hervé, Ali Hafiz, Mohamed Khrouf, Olivier Morel, and Pascale Chavatte-Palmer. "Evaluation of the rabbit as an experimental model for human uterine synechia." Journal of Human Reproductive Sciences 5, no. 2 (2012): 175. http://dx.doi.org/10.4103/0974-1208.101017.

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Moleiro, Maria Lúcia, Rosa Zulmira, Helena Veloso, Rafael Brás, Raquel Reis, Susana Carvalho, and Alexandre Morgado. "Hyaluronic acid gel after ressectoscopy for uterine synechiae in perimenopause - case report." Maturitas 124 (June 2019): 188–89. http://dx.doi.org/10.1016/j.maturitas.2019.04.200.

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Umdagas, H. A., B. M. Kawuwa, U. S. Hajara, and S. Mohammed. "Prevalence of uterine synechiae among infertile females in a Nigerian teaching hospital." Journal of Obstetrics and Gynaecology 26, no. 4 (January 2006): 351–52. http://dx.doi.org/10.1080/01443610600613458.

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Fernandez, H., P. Capmas, and A. Nazac. "Uterine Synechiae After Hysteroscopic Myomectomy: Should We Use Bipolar or Monopolar Energy?" Journal of Minimally Invasive Gynecology 23, no. 7 (November 2016): S7. http://dx.doi.org/10.1016/j.jmig.2016.08.020.

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Henderson, SD, and KH Roy. "Suture Technique for Lysis of Lower Uterine Segment Synechiae After Complete Septoplasty." Journal of Minimally Invasive Gynecology 23, no. 7 (November 2016): S135. http://dx.doi.org/10.1016/j.jmig.2016.08.391.

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Gurgan, T., H. Yarali, B. Urman, V. Dagli, and L. Dogan. "Uterine rupture at 36 weeks' gestation after hysteroscopic lysis of synechiae due to tuberculosis and accidental uterine perforation." Journal of the American Association of Gynecologic Laparoscopists 2, no. 4 (August 1995): S18. http://dx.doi.org/10.1016/s1074-3804(05)80515-8.

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Kang, H., and J. Park. "EP19.11: Mesensteric venous thrombosis and uterine synechiae after uterine arterial embolisation for postpartum bleeding due to placenta accreta." Ultrasound in Obstetrics & Gynecology 50 (September 2017): 350. http://dx.doi.org/10.1002/uog.18638.

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Yoshimasa, Yushi, and Tetsuo Maruyama. "Bioengineering of the Uterus." Reproductive Sciences 28, no. 6 (April 7, 2021): 1596–611. http://dx.doi.org/10.1007/s43032-021-00503-8.

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Abstract:
AbstractImpairment of uterine structure and function causes infertility, pregnancy loss, and perinatal complications in humans. Some types of uterine impairments such as Asherman’s syndrome, also known as uterine synechiae, can be treated medically and surgically in a standard clinical setting, but absolute defects of uterine function or structure cannot be cured by conventional approaches. To overcome such hurdles, partial or whole regeneration and reconstruction of the uterus have recently emerged as new therapeutic strategies. Transplantation of the whole uterus into patients with uterine agenesis results in the successful birth of children. However, it remains an experimental treatment with numerous difficulties such as the need for continuous and long-term use of immunosuppressive drugs until a live birth is achieved. Thus, the generation of the uterus by tissue engineering technologies has become an alternative but indispensable therapeutic strategy to treat patients without a functional or well-structured uterus. For the past 20 years, the bioengineering of the uterus has been studied intensively in animal models, providing the basis for clinical applications. A variety of templates and scaffolds made from natural biomaterials, synthetic materials, or decellularized matrices have been characterized to efficiently generate the uterus in a manner similar to the bioengineering of other organs and tissues. The goal of this review is to provide a comprehensive overview and perspectives of uterine bioengineering focusing on the type, preparation, and characteristics of the currently available scaffolds.
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UEDA, Yusuke, Masaya HIROSE, Takuma ITO, Koji YASUMOTO, Hiromi KAWAGUCHI, Akira MUNESHIGE, and Masataka NAKAJIMA. "Uterine synechia with initial manifestation of intrauterine cyst in second trimester of pregnancy." Choonpa Igaku 43, no. 4 (2016): 593–97. http://dx.doi.org/10.3179/jjmu.jjmu.a.62.

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Chen, F. P., Y. K. Soong, and Y. L. Hui. "Successful treatment of severe uterine synechiae with transcervical resectoscopy combined with laminaria tent." Human Reproduction 12, no. 5 (May 1, 1997): 943–47. http://dx.doi.org/10.1093/humrep/12.5.943.

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Vendittelli, Françoise, Denis Savary, Brigitte Storme, Virginie Rieu, Pascal Chabrot, Cécile Charpy, Didier Lémery, and Bernard Jacquetin. "Ovarian thrombosis and uterine synechiae after arterial embolization for a late postpartum haemorrhage." Case Reports in Women's Health 5 (January 2015): 1–4. http://dx.doi.org/10.1016/j.crwh.2014.10.001.

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Touboul, Cyril, Hervé Fernandez, Xavier Deffieux, Richard Berry, René Frydman, and Amélie Gervaise. "Uterine synechiae after bipolar hysteroscopic resection of submucosal myomas in patients with infertility." Fertility and Sterility 92, no. 5 (November 2009): 1690–93. http://dx.doi.org/10.1016/j.fertnstert.2008.08.108.

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48

K., Ashok Kumar, Sathya P., and Sreelatha Sampathkumar. "Study of hysteroscopic evaluation in patients with abnormal uterine bleeding." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 4 (March 30, 2017): 1413. http://dx.doi.org/10.18203/2320-1770.ijrcog20171401.

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Background: Abnormal uterine bleeding in women is the commonest presenting complaint which accounts for one third of all gynecological consultations. It not only causes discomfort, inconvenience to healthy women but also affects their quality of life and impose financial burden on them. This insists the physician to diagnose its etiology and provide appropriate treatment. Hysteroscopy guided biopsy is a simple, safe, reliable procedure in the diagnosis of abnormal uterine bleeding. The objective of the study was to evaluate the uterine pathology in premenopausal women with abnormal uterine bleeding by hysteroscopy.Methods: This prospective study was conducted at ESIC-MC and PGIMSR, Rajajinagar, Bangalore, in 50 premenopausal women with abnormal uterine bleeding over 18 months from Dec 2012 to May 2014. All 50 women were subjected to diagnostic hysteroscopy followed by curettage. The sample was sent to histopathological examination. Data was collected and analyzed.Results: In the present study, abnormal uterine bleeding was more common in 41-45yrs of age. The commonest presenting complaint was heavy menstrual bleeding (menorrhagia) in 54% of cases. The abnormal findings on hysteroscopy were: Hyperplasia 42%, endometrial polyp 22%, sub-mucous myoma 4%, carcinoma endometrium 2%, synechiae 2% and endometritis 2%. Negative hysteroscopic view was seen in 26%. The sensitivity, specificity, positive and negative predictive value of hysteroscopy was 91.89%, 92.31%, 97.14% and 80% respectively. The overall diagnostic accuracy of hysteroscopy was 92%.Conclusions: Hysteroscopy and its directed biopsy renders high diagnostic accuracy in patients with abnormal uterine bleeding and thereby guiding them for further management.
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Finberg, H. J. "Uterine synechiae in pregnancy: expanded criteria for recognition and clinical significance in 28 cases." Journal of Ultrasound in Medicine 10, no. 10 (October 1991): 547–55. http://dx.doi.org/10.7863/jum.1991.10.10.547.

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Oh, S. T. "O-042 Is hysteroscopic lysis necessary in mild uterine synechia for increasing pregnancy rate?" Fertility and Sterility 68 (January 1997): S21—S22. http://dx.doi.org/10.1016/s0015-0282(97)90674-9.

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