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1

Leimar, Olof, and Juha Tuomi. "Synergistic selection and graded traits." Evolutionary Ecology 12, no. 1 (1998): 59–71. http://dx.doi.org/10.1023/a:1006507023520.

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2

Tuomi, Juha, and Magnus Augner. "Synergistic Selection of Unpalatability in Plants." Evolution 47, no. 2 (1993): 668. http://dx.doi.org/10.2307/2410078.

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3

Tuomi, Juha, and Magnus Augner. "SYNERGISTIC SELECTION OF UNPALATABILITY IN PLANTS." Evolution 47, no. 2 (1993): 668–72. http://dx.doi.org/10.1111/j.1558-5646.1993.tb02120.x.

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4

Rosenberg, Gary. "Aposematism and Synergistic Selection in Marine Gastropods." Evolution 45, no. 2 (1991): 451. http://dx.doi.org/10.2307/2409681.

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5

Rosenberg, Gary. "APOSEMATISM AND SYNERGISTIC SELECTION IN MARINE GASTROPODS." Evolution 45, no. 2 (1991): 451–54. http://dx.doi.org/10.1111/j.1558-5646.1991.tb04421.x.

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6

Falconer, D. S. "Selection in different environments: effects on environmental sensitivity (reaction norm) and on mean performance." Genetical Research 56, no. 1 (1990): 57–70. http://dx.doi.org/10.1017/s0016672300028883.

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SummaryTo simplify the description of selection in two environments the terms ‘ antagonistic’ and ‘synergistic’ are used. Selection upwards in a bad environment or downwards in a good environment is antagonistic, the selection and the environment acting in opposite directions on the character. Synergistic selection is the reverse, upwards in a good environment or downwards in a bad, selection and environment acting in the same direction. Published experiments are reviewed to see how well they agree with two expectations. First, Jinks & Connolly (1973) showed that antagonistic selection red
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7

Kondrashov, A. S. "Muller's ratchet under epistatic selection." Genetics 136, no. 4 (1994): 1469–73. http://dx.doi.org/10.1093/genetics/136.4.1469.

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Abstract In a finite asexual population mean fitness may decrease by a process known as Muller's ratchet, which proceeds if all individuals with the minimum number of deleterious alleles are randomly lost. If these alleles have independent effects on fitness, previous analysis suggested that the rate of this decrease either remains constant or, if accumulation of mutations leads to the decline of the population size, grows. Here I show that this conclusion is quite sensitive to the assumption of independence. If deleterious alleles have synergistic fitness effects, then, as the ratchet advance
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8

Corning, Peter A., and Eörs Szathmáry. "“Synergistic selection”: A Darwinian frame for the evolution of complexity." Journal of Theoretical Biology 371 (April 2015): 45–58. http://dx.doi.org/10.1016/j.jtbi.2015.02.002.

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9

Boughman, Janette W., and Richard Svanbäck. "Synergistic selection between ecological niche and mate preference primes diversification." Evolution 71, no. 1 (2016): 6–22. http://dx.doi.org/10.1111/evo.13089.

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10

Sohail, Mashaal, Olga A. Vakhrusheva, Jae Hoon Sul, et al. "Negative selection in humans and fruit flies involves synergistic epistasis." Science 356, no. 6337 (2017): 539–42. http://dx.doi.org/10.1126/science.aah5238.

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11

Wilkins, Jon F., Peter T. McHale, Joshua Gervin, and Arthur D. Lander. "Survival of the Curviest: Noise-Driven Selection for Synergistic Epistasis." PLOS Genetics 12, no. 4 (2016): e1006003. http://dx.doi.org/10.1371/journal.pgen.1006003.

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12

Sorokin, Maxim, Roman Kholodenko, Maria Suntsova, et al. "Oncobox Bioinformatical Platform for Selecting Potentially Effective Combinations of Target Cancer Drugs Using High-Throughput Gene Expression Data." Cancers 10, no. 10 (2018): 365. http://dx.doi.org/10.3390/cancers10100365.

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Sequential courses of anticancer target therapy lead to selection of drug-resistant cells, which results in continuous decrease of clinical response. Here we present a new approach for predicting effective combinations of target drugs, which act in a synergistic manner. Synergistic combinations of drugs may prevent or postpone acquired resistance, thus increasing treatment efficiency. We cultured human ovarian carcinoma SKOV-3 and neuroblastoma NGP-127 cancer cell lines in the presence of Tyrosine Kinase Inhibitors (Pazopanib, Sorafenib, and Sunitinib) and Rapalogues (Temsirolimus and Everolim
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13

Atuonwu, James C., Gerrit van Straten, Henk C. van Deventer, and Antonius J. B. van Boxtel. "Synergistic Process Design: Reducing Drying Energy Consumption by Optimal Adsorbent Selection." Industrial & Engineering Chemistry Research 52, no. 18 (2013): 6201–10. http://dx.doi.org/10.1021/ie3030449.

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14

Ganguly, Debabani, Weihong Zhang, and Jianhan Chen. "Synergistic folding of two intrinsically disordered proteins: searching for conformational selection." Mol. BioSyst. 8, no. 1 (2012): 198–209. http://dx.doi.org/10.1039/c1mb05156c.

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15

She, Jian Guo, Xian Zhen Meng, and Ning Chen. "The Research and Development Based on the UV + US Synergistic Sterilizer." Applied Mechanics and Materials 253-255 (December 2012): 908–13. http://dx.doi.org/10.4028/www.scientific.net/amm.253-255.908.

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Harmful microbes carried by ballast water have led to serious damage, the skill of ultraviolet collaborative ultrasonic is efficient and pollution-free. Using this kind of technology, it designed the sterilization, including tubes selection, UV doses calculation, cylinder body design, US power and frequency design, US transducer selection etc. After the experiment of inactivated algae the results show that this kind of technology is feasible in ballast water treatment.
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16

Charlesworth, Brian. "Mutation-selection balance and the evolutionary advantage of sex and recombination." Genetical Research 55, no. 3 (1990): 199–221. http://dx.doi.org/10.1017/s0016672300025532.

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SummaryMutation-selection balance in a multi-locus system is investigated theoretically, using a modification of Bulmer's infinitesimal model of selection on a normally-distributed quantitative character, taking the number of mutations per individual (n) to represent the character value. The logarithm of the fitness of an individual with n mutations is assumed to be a quadratic, decreasing function of n. The equilibrium properties of infinitely large asexual populations, random-mating populations lacking genetic recombination, and random-mating populations with arbitrary recombination frequenc
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17

Suwa, M., T. Nakamura, and S. Katsuta. "Heredity of muscle fiber composition and correlated response of the synergistic muscle in rats." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 271, no. 2 (1996): R432—R436. http://dx.doi.org/10.1152/ajpregu.1996.271.2.r432.

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The extent to which muscle fiber composition was determined by genes transmitted from parents and the correlated response of the synergistic muscle were analysed by using successive selection of rats. The foundation population (G0) was prepared by random choice from heterogeneous stock produced by random mating of three strains, Wistar-Imamichi, Fischer 344, and Donryu. Selective mating for a high percentage of fast-twitch fibers (%FT) in the deep portion of the lateral head of the gastrocnemius muscle and random mating were made from G0 to the seventh generation (G7). Successive selection cau
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18

Charlesworth, B., M. T. Morgan, and D. Charlesworth. "Multilocus models of inbreeding depression with synergistic selection and partial self-fertilization." Genetical Research 57, no. 2 (1991): 177–94. http://dx.doi.org/10.1017/s0016672300029256.

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SummaryMean fitness and inbreeding depression values in multi-locus models of the control of fitness were studied, using both a model of mutation to deleterious alleles, and a model of heterozygote advantage. Synergistic fitness interactions between loci were assumed, to find out if this more biologically plausible model altered the conclusions we obtained previously using a model of multiplicative interactions. Systems of unlinked loci were assumed. We used deterministic computer calculations, and approximations based on normal or Poisson theory. These approximations gave good agreement with
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19

Rodriguez‐Exposito, Eduardo, Francisco Garcia‐Gonzalez, and Michal Polak. "Individual and synergistic effects of male external genital traits in sexual selection." Journal of Evolutionary Biology 33, no. 1 (2019): 67–79. http://dx.doi.org/10.1111/jeb.13546.

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20

Önskog, Jenny, Eva Freyhult, Mattias Landfors, Patrik Rydén, and Torgeir R. Hvidsten. "Classification of microarrays; synergistic effects between normalization, gene selection and machine learning." BMC Bioinformatics 12, no. 1 (2011): 390. http://dx.doi.org/10.1186/1471-2105-12-390.

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21

Gessler, Damian D. G., and Shizhong Xu. "Meiosis and the Evolution of Recombination at Low Mutation Rates." Genetics 156, no. 1 (2000): 449–56. http://dx.doi.org/10.1093/genetics/156.1.449.

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Abstract The classical understanding of recombination is that in large asexual populations with multiplicative fitness, linkage disequilibrium is negligible, and thus there is no selective agent driving an allele for recombination. This has led researchers to recognize the importance of synergistic epistatic selection in generating negative linkage disequilibrium that thereby renders an advantage to recombination. Yet data on such selection is equivocal, and various works have shown that synergistic epistasis per se, when left unquantified in its magnitude or operation, is not sufficient to dr
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22

de Visser, J. A. G. M. Arjan, Rolf F. Hoekstra, and Herman van den Ende. "An Experimental Test for Synergistic Epistasis and Its Application in Chlamydomonas." Genetics 145, no. 3 (1997): 815–19. http://dx.doi.org/10.1093/genetics/145.3.815.

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Theoretically, one of the most general benefits of sex is given by its function in facilitating selection against deleterious mutations. This advantage of sex may be deterministic if deleterious mumtiom affect the fitness of an individual in a synergistic way, i.e., if mutations increase each others' negative fitness effect. We present a new test for synergistic epistasis that considers the skewnessof the log fitness distribution of offspring from a cross. We applied this test to data of the unicellular alga Chlamydomonas moewussii. For this purpose, two crosses were made: one between two stra
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23

Maçon, Anthony L. B., Samuel J. Page, Justin J. Chung, et al. "A structural and physical study of sol–gel methacrylate–silica hybrids: intermolecular spacing dictates the mechanical properties." Physical Chemistry Chemical Physics 17, no. 43 (2015): 29124–33. http://dx.doi.org/10.1039/c5cp04656d.

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Sol–gel hybrids are inorganic/organic co-networks with nanoscale interactions between the components leading to unique synergistic mechanical properties, which can be tailored, via a selection of the organic moiety.
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24

CHARLESWORTH, BRIAN. "The effect of synergistic epistasis on the inbreeding load." Genetical Research 71, no. 1 (1998): 85–89. http://dx.doi.org/10.1017/s0016672398003140.

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The magnitude of inbreeding depression in Drosophila melanogaster appears too large to be accounted for by mutational load with multiplicative fitness interactions among loci, if current estimates of mutation and selection parameters are valid. One possible explanation for this discrepancy is synergistic epistasis among the fitness effects of deleterious mutations. A simple model of the effect of synergistic epistasis on the inbreeding load is developed. This model is used to show that deleterious mutations could account for the Drosophila data on the effects of inbreeding on components of fit
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25

Miles, Meredith C., and Matthew J. Fuxjager. "Synergistic selection regimens drive the evolution of display complexity in birds of paradise." Journal of Animal Ecology 87, no. 4 (2018): 1149–59. http://dx.doi.org/10.1111/1365-2656.12824.

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26

Wortman, Jeremy R., Alexander J. Adduci, and Aaron D. Sodickson. "Synergistic Radiation Dose Reduction by Combining Automatic Tube Voltage Selection and Iterative Reconstruction." Journal of Thoracic Imaging 31, no. 2 (2016): 111–18. http://dx.doi.org/10.1097/rti.0000000000000196.

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27

Georges, M., and J. M. Massey. "Velogenetics, or the synergistic use of marker assisted selection and germ-line manipulation." Theriogenology 35, no. 1 (1991): 151–59. http://dx.doi.org/10.1016/0093-691x(91)90154-6.

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28

Lange, Alexander, Robert Schwieger, Julia Plöntzke, Stefan Schäfer, and Susanna Röblitz. "Follicular competition in cows: the selection of dominant follicles as a synergistic effect." Journal of Mathematical Biology 78, no. 3 (2018): 579–606. http://dx.doi.org/10.1007/s00285-018-1284-0.

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29

van Galen, Martijn, Ruben Higler, and Joris Sprakel. "Allosteric pathway selection in templated assembly." Science Advances 5, no. 10 (2019): eaaw3353. http://dx.doi.org/10.1126/sciadv.aaw3353.

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Assembling large numbers of molecular building blocks into functional nanostructures is no trivial task. It relies on guiding building blocks through complex energy landscapes shaped by synergistic and antagonistic supramolecular interactions. In nature, the use of molecular templates is a potent strategy to navigate the process to the desired structure with high fidelity. Yet, nature’s templating strategy remains to be fully exploited in man-made nanomaterials. Designing effective template-guided self-assembling systems can only be realized through precise insight into how the chemical design
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30

Vipin, Chembili, Kanekar Saptami, Fathima Fida, et al. "Potential synergistic activity of quercetin with antibiotics against multidrug-resistant clinical strains of Pseudomonas aeruginosa." PLOS ONE 15, no. 11 (2020): e0241304. http://dx.doi.org/10.1371/journal.pone.0241304.

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Development of drug resistance in opportunistic pathogens is one of the major healthcare challenges associated with infection management. Combination therapy has many advantages due to the simultaneous action of two drugs on two separate cellular targets. However, selection of the drugs should offer safety and synergistic interaction against most of the strains. Here, the efficacy of antibiotics in combination with quercetin, a natural flavonoid capable of targeting quorum sensing was tested against biofilm-forming Pseudomonas aeruginosa strains previously isolated from catheter associated uri
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31

Hansen, Thomas F., and Günter P. Wagner. "Epistasis and the Mutation Load: A Measurement-Theoretical Approach." Genetics 158, no. 1 (2001): 477–85. http://dx.doi.org/10.1093/genetics/158.1.477.

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Abstract An approximate solution for the mean fitness in mutation-selection balance with arbitrary order of epistatic interaction is derived. The solution is based on the assumptions of coupling equilibrium and that the interaction effects are multilinear. We find that the effect of m-order epistatic interactions (i.e., interactions among groups of m loci) on the load is dependent on the total genomic mutation rate, U, to the mth power. Thus, higher-order gene interactions are potentially important if U is large and the interaction density among loci is not too low. The solution suggests that
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32

Taylor, Peter, and Wes Maciejewski. "An inclusive fitness analysis of synergistic interactions in structured populations." Proceedings of the Royal Society B: Biological Sciences 279, no. 1747 (2012): 4596–603. http://dx.doi.org/10.1098/rspb.2012.1408.

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We study the evolution of a pair of competing behavioural alleles in a structured population when there are non-additive or ‘synergistic’ fitness effects. Under a form of weak selection and with a simple symmetry condition between a pair of competing alleles, Tarnita et al. provide a surprisingly simple condition for one allele to dominate the other. Their condition can be obtained from an analysis of a corresponding simpler model in which fitness effects are additive. Their result uses an average measure of selective advantage where the average is taken over the long-term—that is, over all po
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33

SVEC, FRANK, and JOHNNY R. PORTER. "Synergistic Anorectic Effect of Dehydroepiandrosterone and Fenfluramine on Zucker Rat Food Intake and Selection." Annals of the New York Academy of Sciences 774, no. 1 (2006): 332–34. http://dx.doi.org/10.1111/j.1749-6632.1995.tb17401.x-i1.

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34

Moland, Ellen S., David W. Craft, Seong-geun Hong, et al. "In Vitro Activity of Tigecycline against Multidrug-Resistant Acinetobacter baumannii and Selection of Tigecycline-Amikacin Synergy." Antimicrobial Agents and Chemotherapy 52, no. 8 (2008): 2940–42. http://dx.doi.org/10.1128/aac.01581-07.

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ABSTRACT Polymyxin B, minocycline, and tigecycline were the most potent of 10 antibiotics against 170 isolates of multidrug-resistant Acinetobacter baumannii. In time-kill studies, the exposure of a highly tigecycline-resistant isolate to tigecycline resulted in enhanced susceptibility to amikacin and synergistic bactericidal activities of the two drugs.
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Tascini, Carlo, Enrico Tagliaferri, Tommaso Giani, et al. "Synergistic Activity of Colistin plus Rifampin against Colistin-Resistant KPC-Producing Klebsiella pneumoniae." Antimicrobial Agents and Chemotherapy 57, no. 8 (2013): 3990–93. http://dx.doi.org/10.1128/aac.00179-13.

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ABSTRACTInfections caused by carbapenem-resistant KPC-producingKlebsiella pneumoniaeare responsible for high rates of mortality and represent a major therapeutic challenge, especially when the isolates are also resistant to colistin. We used the checkerboard method to evaluate the synergistic activity of 10 antibiotic combinations against 13 colistin-resistant KPC-producingK. pneumoniaeisolates (colistin MIC range of 8 to 128 mg/liter). Colistin plus rifampin was the only combination that demonstrated consistent synergistic bacteriostatic activity against 13/13 strains tested, reducing the col
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36

Charlesworth, B., and N. H. Barton. "Recombination load associated with selection for increased recombination." Genetical Research 67, no. 1 (1996): 27–41. http://dx.doi.org/10.1017/s0016672300033450.

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SummaryExperiments on Drosophila suggest that genetic recombination may result in lowered fitness of progeny (a ‘recombination load’). This has been interpreted as evidence either for a direct effect of recombination on fitness, or for the maintenance of linkage disequilibria by epistatic selection. Here we show that such a recombination load is to be expected even if selection favours increased genetic recombination. This is because of the fact that, although a modifier may suffer an immediate loss of fitness if it increases recombination, it eventually becomes associated with a higher additi
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37

Acker, Paul, Sarah J. Burthe, Mark A. Newell, et al. "Episodes of opposing survival and reproductive selection cause strong fluctuating selection on seasonal migration versus residence." Proceedings of the Royal Society B: Biological Sciences 288, no. 1951 (2021): 20210404. http://dx.doi.org/10.1098/rspb.2021.0404.

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Quantifying temporal variation in sex-specific selection on key ecologically relevant traits, and quantifying how such variation arises through synergistic or opposing components of survival and reproductive selection, is central to understanding eco-evolutionary dynamics, but rarely achieved. Seasonal migration versus residence is one key trait that directly shapes spatio-seasonal population dynamics in spatially and temporally varying environments, but temporal dynamics of sex-specific selection have not been fully quantified. We fitted multi-event capture–recapture models to year-round ring
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38

Yilancioglu. "Antimicrobial Drug Interactions: Systematic Evaluation of Protein and Nucleic Acid Synthesis Inhibitors." Antibiotics 8, no. 3 (2019): 114. http://dx.doi.org/10.3390/antibiotics8030114.

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Antimicrobial multidrug resistance and its transmission among strains are serious problems. Success rate is decreased and treatment options are narrowed due to increasing bacterial multidrug resistance. On the other hand, the need for long-term efforts to discover new antibiotics and difficulties finding new treatment protocols make this problem more complex. Combination therapy, especially with synergistic use of antimicrobials is a rational treatment option with huge benefits. Thus, screening antibiotic interactions is crucial for finding better treatment options. Clinicians currently use co
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39

Hao, Jia, Meijing Gao, Xiaodan Hu, et al. "Synergistic selection of a Helicoverpa armigera cadherin fragment with Cry1Ac in different cells and insects." International Journal of Biological Macromolecules 164 (December 2020): 3667–75. http://dx.doi.org/10.1016/j.ijbiomac.2020.08.175.

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40

Valderrama, María-José, María Alfaro, Icíar Rodríguez-Avial, Elvira Baos, Carmen Rodríguez-Avial, and Esther Culebras. "Synergy of Linezolid with Several Antimicrobial Agents against Linezolid-Methicillin-Resistant Staphylococcal Strains." Antibiotics 9, no. 8 (2020): 496. http://dx.doi.org/10.3390/antibiotics9080496.

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Linezolid is a synthetic oxazolydinone active against multi-resistant Gram-positive cocci that inhibits proteins synthesis by interacting with the 50S ribosomal subunit. Although linezolid-resistant strains are infrequent, several outbreaks have been recently described, associated with prolonged treatment with the antibiotic. As an alternative to monotherapy, the combination of different antibiotics is a commonly used option to prevent the selection of resistant strains. In this work, we evaluated combinations of linezolid with classic and new aminoglycosides (amikacin, gentamicin and plazomic
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41

Bablani, Annushree, Damodar Reddy Edla, Diwakar Tripathi, Shubham Dodia, and Sridhar Chintala. "A Synergistic Concealed Information Test With Novel Approach for EEG Channel Selection and SVM Parameter Optimization." IEEE Transactions on Information Forensics and Security 14, no. 11 (2019): 3057–68. http://dx.doi.org/10.1109/tifs.2019.2913798.

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42

Yoshikawa, Takeshi, Masato Kobayashi, and Hiromi Nakai. "Divide-and-conquer-based symmetry adapted cluster method: Synergistic effect of subsystem fragmentation and configuration selection." International Journal of Quantum Chemistry 113, no. 3 (2012): 218–23. http://dx.doi.org/10.1002/qua.24093.

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43

Hastings, Ian M., Lorna H. Bootland, and William G. Hill. "The role of growth hormone in lines of mice divergently selected on body weight." Genetical Research 61, no. 2 (1993): 101–6. http://dx.doi.org/10.1017/s0016672300031207.

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SummaryAn understanding of the physiological and genetic changes which determine the response to selection is critical for both evolutionary theory and to assess the application of new molecular techniques to commercial animal breeding. We investigated an aspect of physiology, growth hormone (GH) metabolism, which might a priori have been expected to play a large part in the response of mouse lines selected for high or low body weight. Disruption of endogenous GH or addition of exogenous GH had similar proportionate effects on body weight in both lines of mice (although differences in body com
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44

Wang, Silu, and Marla B. Sokolowski. "Aggressive behaviours, food deprivation and the foraging gene." Royal Society Open Science 4, no. 4 (2017): 170042. http://dx.doi.org/10.1098/rsos.170042.

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A pleiotropic gene governs multiple traits, which might constrain the evolution of complexity due to conflicting selection on these traits. However, if the pleiotropic effect is modular, then this can facilitate synergistic responses to selection on functionally related traits, thereby leveraging the evolution of complexity. To understand the evolutionary consequence of pleiotropy, the relation among functionally different traits governed by the same gene is key. We examined a pleiotropic function of the foraging ( for ) gene with its rover and sitter allelic variants in fruit fly, Drosophila
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45

Winstanley, P. A., E. K. Mberu, I. S. Szwandt, A. M. Breckenridge, and W. M. Watkins. "In vitro activities of novel antifolate drug combinations against Plasmodium falciparum and human granulocyte CFUs." Antimicrobial Agents and Chemotherapy 39, no. 4 (1995): 948–52. http://dx.doi.org/10.1128/aac.39.4.948.

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The potency of antimalarial dihydrofolate reductase inhibitors, alone and in synergistic combination with dihydropteroate synthetase inhibitors, against the Kenyan K39 strain of Plasmodium falciparum (pyrimethamine resistant) and against normal replicating human bone marrow cells in in vitro culture has been studied. Therapeutic indices and rank order of synergistic potency were derived. Trimethoprim, pyrimethamine, and the quinazolines WR159412 and WR158122 had the smallest therapeutic indices (1.39, 4.38, 2.56, and 90.0, respectively), while the three triazines clociguanil, WR99210, and chlo
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Gawdzinska, Katarzyna, Sandra Paszkiewicz, Elzbieta Piesowicz, et al. "Preparation and Characterization of Hybrid Nanocomposites for Dental Applications." Applied Sciences 9, no. 7 (2019): 1381. http://dx.doi.org/10.3390/app9071381.

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The study involved research related to the selection of the material with improved functional properties that can be used for dental prostheses. An innovative system of nanofillers, that differ in shape, by means of gelatin-modified halloysite nanotubes (HNTs-g) along with silane-coupled aluminum trihydrate (ATH-sil) was prepared, in order to observe a synergistic improvement of acrylic material (methyl methacrylate with methyl methacrylate monomer (MM/mMM)). Selected mechanical properties of manufactured nanocomposites, along with utilitarian properties, like hardness, buffer solution absorpt
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47

Scrivo, Raffaele, and Angela Viglianisi. "Urban Development Agreement: “Metropolitan Perspectives 2013” The Public - Private Partnership in Urban and Infrastructure Development in the North Area of Reggio Calabria." Advanced Engineering Forum 11 (June 2014): 271–75. http://dx.doi.org/10.4028/www.scientific.net/aef.11.271.

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The Plan for the City, can be defined more like an operative program than a plan. In his criteria it is possible to identify a systemic, synergistic and sustanaible approach. The approach was that to define a method to integrate the time with economic and social factors, defining a more large concept of sustainability. The path has involved local stakeholders to understand their need, even often conflictual, between public and private, translating them into selection criteria and go on to apath of selection of actions. These actions will follow on iter on Public - Private partnership, three go
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48

Abendroth, Julie A., Erin E. Blankenship, Alex R. Martin, and Fred W. Roeth. "Joint Action Analysis Utilizing Concentration Addition and Independent Action Models." Weed Technology 25, no. 3 (2011): 436–46. http://dx.doi.org/10.1614/wt-d-10-00102.1.

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In weed science literature, models such as concentration addition, independent action, effect summation, and the parallel line assay technique have been used to predict and analyze whole-plant response to herbicide mixtures. Although a joint action reference model is necessary for determining whether the herbicide mixture provides less than (antagonistic), equal to (zero-interaction or additive), or greater than (synergistic) expected control, model selection often occurs with little regard to the model's underlying biological assumptions. The joint action models of concentration addition (CA)
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Tamura, Tomokazu, Yoshihiro Sakoda, Fumi Yoshino, et al. "Selection of Classical Swine Fever Virus with Enhanced Pathogenicity Reveals Synergistic Virulence Determinants in E2 and NS4B." Journal of Virology 86, no. 16 (2012): 8602–13. http://dx.doi.org/10.1128/jvi.00551-12.

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Classical swine fever virus (CSFV) is the causative agent of classical swine fever (CSF), a highly contagious disease of pigs. There are numerous CSFV strains that differ in virulence, resulting in clinical disease with different degrees of severity. Low-virulent and moderately virulent isolates cause a mild and often chronic disease, while highly virulent isolates cause an acute and mostly lethal hemorrhagic fever. The live attenuated vaccine strain GPE−was produced by multiple passages of the virulent ALD strain in cells of swine, bovine, and guinea pig origin. With the aim of identifying th
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Guimarães, Alexandre Silva, and Marcelo Borges Mansur. "Selection of a synergistic solvent extraction system to remove calcium and magnesium from concentrated nickel sulfate solutions." Hydrometallurgy 175 (January 2018): 250–56. http://dx.doi.org/10.1016/j.hydromet.2017.12.001.

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