Relevant bibliographies by topics / Syntenin/syndecan interaction

Contents

  1. Journal articles
  2. Dissertations / Theses

Academic literature on the topic 'Syntenin/syndecan interaction'

Author: Grafiati
Published: 25 May 2024
Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Syntenin/syndecan interaction.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Syntenin/syndecan interaction"

1

Zimmermann, Pascale, Zhe Zhang, Gisèle Degeest, et al. "Syndecan Recyling Is Controlled by Syntenin-PIP2 Interaction and Arf6." Developmental Cell 9, no. 3 (2005): 377–88. http://dx.doi.org/10.1016/j.devcel.2005.07.011.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Zimmermann, Pascale, Zhe Zhang, Gisèle Degeest, et al. "Syndecan Recycling Is Controlled by Syntenin-PIP2 Interaction and Arf6." Developmental Cell 9, no. 5 (2005): 721. http://dx.doi.org/10.1016/j.devcel.2005.10.011.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

BASS, Mark D., and Martin J. HUMPHRIES. "Cytoplasmic interactions of syndecan-4 orchestrate adhesion receptor and growth factor receptor signalling." Biochemical Journal 368, no. 1 (2002): 1–15. http://dx.doi.org/10.1042/bj20021228.

Full text
Abstract:
Syndecan-4 is a ubiquitous transmembrane proteoglycan that localizes to the focal adhesions of adherent cells and binds to a range of extracellular ligands, including growth factors and extracellular-matrix proteins. Engagement of syndecan-4 is essential for adhesion formation in cells adhering via certain integrins, and for cell proliferation and migration in response to growth factors. The cytoplasmic domain of syndecan-4 interacts with a number of signalling and structural proteins, and both extracellular and cytoplasmic domains are necessary for regulated activation of associated transmemb
APA, Harvard, Vancouver, ISO, and other styles
4

Lee, Hawon, Yeonhee Kim, Youngsil Choi, Sojoong Choi, Eunkyung Hong, and Eok-Soo Oh. "Syndecan-2 cytoplasmic domain regulates colon cancer cell migration via interaction with syntenin-1." Biochemical and Biophysical Research Communications 409, no. 1 (2011): 148–53. http://dx.doi.org/10.1016/j.bbrc.2011.04.135.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Imjeti, Naga Sailaja, Kerstin Menck, Antonio Luis Egea-Jimenez, et al. "Syntenin mediates SRC function in exosomal cell-to-cell communication." Proceedings of the National Academy of Sciences 114, no. 47 (2017): 12495–500. http://dx.doi.org/10.1073/pnas.1713433114.

Full text
Abstract:
The cytoplasmic tyrosine kinase SRC controls cell growth, proliferation, adhesion, and motility. The current view is that SRC acts primarily downstream of cell-surface receptors to control intracellular signaling cascades. Here we reveal that SRC functions in cell-to-cell communication by controlling the biogenesis and the activity of exosomes. Exosomes are viral-like particles from endosomal origin that can reprogram recipient cells. By gain- and loss-of-function studies, we establish that SRC stimulates the secretion of exosomes having promigratory activity on endothelial cells and that synt
APA, Harvard, Vancouver, ISO, and other styles
6

Pradhan, Anjan K., Jinkal Modi, Santanu Maji, et al. "Abstract 3394: Simultaneous targeting of the PDZ1 and PDZ2 domains of MDA-9 inhibits melanoma metastasis." Cancer Research 83, no. 7_Supplement (2023): 3394. http://dx.doi.org/10.1158/1538-7445.am2023-3394.

Full text
Abstract:
Abstract Metastasis poses significant obstacles to effective therapy and drug development. Melanoma differentiation-associated gene-9/Syntenin-1/Syndecan Binding Protein (MDA-9) is a pro-metastatic gene robustly and differentially expressed in cancer cells in comparison with corresponding adjacent normal/primary cells and represents an attractive therapeutic target to inhibit cancer cell dissemination and tumor growth. MDA-9 contains two tandem PDZ domains that provide a nexus for interactions with multiple proteins that can initiate the transcription of metastasis-associated genes. The goal o
APA, Harvard, Vancouver, ISO, and other styles
7

Zhao, Tian, Xiaolan Yang, Guangfei Duan, et al. "Phosphorylation‐regulated phase separation of syndecan‐4 and syntenin promotes the biogenesis of exosomes." Cell Proliferation, April 11, 2024. http://dx.doi.org/10.1111/cpr.13645.

Full text
Abstract:
AbstractThe biogenesis of exosomes that mediate cell‐to‐cell communication by transporting numerous biomolecules to neighbouring cells is an essential cellular process. The interaction between the transmembrane protein syndecan‐4 (SDC4) and cytosolic protein syntenin plays a key role in the biogenesis of exosomes. However, how the relatively weak binding of syntenin to SDC4 efficiently enables syntenin sorting for packaging into exosomes remains unclear. Here, we demonstrate for the first time that SDC4 can undergo liquid–liquid phase separation (LLPS) to form condensates both in vitro and in
APA, Harvard, Vancouver, ISO, and other styles
8

Pradhan, Anjan K., Jinkal Modi, Santanu Maji, et al. "Dual Targeting of the PDZ1 and PDZ2 Domains of MDA-9/Syntenin Inhibits Melanoma Metastasis." Molecular Cancer Therapeutics, September 18, 2023, OF1—OF13. http://dx.doi.org/10.1158/1535-7163.mct-22-0653.

Full text
Abstract:
Abstract Genome-wide gene expression analysis and animal modeling indicate that melanoma differentiation associated gene-9 (mda-9, Syntenin, Syndecan binding protein, referred to as MDA-9/Syntenin) positively regulates melanoma metastasis. The MDA-9/Syntenin protein contains two tandem PDZ domains serving as a nexus for interactions with multiple proteins that initiate transcription of metastasis-associated genes. Although targeting either PDZ domain abrogates signaling and prometastatic phenotypes, the integrity of both domains is critical for full biological function. Fragment-based drug dis
APA, Harvard, Vancouver, ISO, and other styles
9

Hoffer, Laurent, Manon Garcia, Raphael Leblanc, et al. "Discovery of a PDZ Domain Inhibitor Targeting the Syndecan/Syntenin Protein–Protein Interaction: A Semi-Automated “Hit Identification-to-Optimization” Approach." Journal of Medicinal Chemistry, March 20, 2023. http://dx.doi.org/10.1021/acs.jmedchem.2c01569.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Files, Rita, Cláudia Cardoso, Justina Prada, Filipe Silva, and Isabel Pires. "Syndecan-1 as a therapeutic target in squamous cell carcinoma: Current insights and future directions." Journal of Applied Pharmaceutical Science, 2024. http://dx.doi.org/10.7324/japs.2025.212158.

Full text
Abstract:
Squamous cell carcinoma (SCC) is a type of epithelial cancer that originates in the squamous epithelium and can develop in any area of the body covered by this tissue. Cutaneous SCC is characterized by a locally aggressive tumor, highlighting the importance of identifying new therapeutic targets to combat this disease effectively. Syndecan-1, a molecule often deregulated in cutaneous SCC, is a type 1 transmembrane proteoglycan primarily expressed in epithelial and plasma cells. The ectodomain of Syndecan-1 is frequently shed, rendering the molecule soluble and capable of interacting with vario
APA, Harvard, Vancouver, ISO, and other styles

Dissertations / Theses on the topic "Syntenin/syndecan interaction"

1

Garcia, Manon. "Développement de nouveaux agents anticancéreux inhibiteurs de la syntenin." Electronic Thesis or Diss., Aix-Marseille, 2021. http://theses.univ-amu.fr.lama.univ-amu.fr/210312_GARCIA_59el396udxeux306vl471dzd_TH.pdf.

Full text
Abstract:
Les travaux de thèse présentés décrivent l’identification et l’optimisation d’inhibiteurs sélectifs du complexe protéique syntenin/syndecan, grâce à une stratégie de « Fragment-based drug design » (FBDD), qui pourrait ouvrir la voie vers de nouvelles thérapies anticancéreuses. L'interaction syntenin/syndecan joue un rôle majeur dans le recyclage des endosomes vers la membrane plasmique, ainsi que dans la biogénèse et la libération des exosomes dérivés de cellules tumorales. Par conséquent, nous avons réalisé un programme de FBDD ciblant sélectivement l’interaction syntenin/syndecan. Pour ce fa
APA, Harvard, Vancouver, ISO, and other styles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography