Academic literature on the topic 'Synthesis. heterocyclic compounds'

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Journal articles on the topic "Synthesis. heterocyclic compounds"

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Luna, Isadora Silva, Rayssa Marques Duarte da Cruz, Ryldene Marques Duarte da Cruz, Rodrigo Santos Aquino de Araújo, and Francisco Jaime Bezerra Mendonça-Junior. "1,4-Dithiane-2,5-diol: A Versatile Synthon for the Synthesis of Sulfur-containing Heterocycles." Current Organic Synthesis 15, no. 8 (2018): 1026–42. http://dx.doi.org/10.2174/1570179415666180821154551.

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Background: 1,4-Dithiane-2,5-diol (1,4-DTD) is the stable dimer of α-mercapto acetaldehyde. This commercially available ambidentade compound is characterized as having in its chemical structure one group that acts as an electrophile and another that acts as a nucleophile, this permits its use as versatile and efficient synthon in synthetic heterocycle procedures. Objective: The aim of this review is to present synthetic applications of 1,4-DTD in heterocyclic chemistry and their applicability to the synthesis of bioactive compounds. Conclusion: Gewald reactions to obtain C-4 and C-5 unsubstitu
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Bakibayev, A. A., K. B. Zhumanov, S. Yu Panshina, et al. "Synthesis methods of phosphorylated carbamide containing acyclic and heterocyclic compounds." Bulletin of the Karaganda University. "Chemistry" series 95, no. 3 (2019): 115–57. http://dx.doi.org/10.31489/2019ch3/115-157.

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Adak, Laksmikanta, and Tubai Ghosh. "Recent Progress in Iron-Catalyzed Reactions Towards the Synthesis of Bioactive Five- and Six-Membered Heterocycles." Current Organic Chemistry 24, no. 22 (2020): 2634–64. http://dx.doi.org/10.2174/1385272824999200714102103.

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Heterocyclic compounds are the largely diverse organic molecules and find prevalent applications in the fine chemical industry, medicinal chemistry and agricultural science. They are also among the most commonly bearing frameworks in numerous drugs and pharmaceutical substances. Therefore, the development of convenient, efficient and environmentally benign methods to produce various types of heterocyclic compounds is an attractive area of research. For the synthesis and functionalization of heterocycles, enormous achievements have been attributed over the past decades. Recently, ironcatalyzed
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Ābele, E., R. Ābele, Ļ. Golomba, J. Višņevska, T. Beresņeva, and K. Rubina. "Oximes of Seven-Membered Heterocyclic Compounds Containing One Heteroatom." Latvian Journal of Chemistry 50, no. 3-4 (2011): 205–22. http://dx.doi.org/10.2478/v10161-011-0071-7.

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Oximes of Seven-Membered Heterocyclic Compounds Containing One Heteroatom Literature data on the synthesis and structure of azepane, oxepane and thiepane oximes were reviewed. Synthesis of novel heterocycles from oximes of seven-membered heterocycles containing one heteroatom were described. Biological activity of oximes of seven-membered heterocycles with one heteroatom was also reviewed.
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Murarka, Sandip, and Andrey Antonchick. "Metal-Catalyzed Oxidative Coupling of Ketones and Ketone Enolates." Synthesis 50, no. 11 (2018): 2150–62. http://dx.doi.org/10.1055/s-0037-1609715.

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Recent years have witnessed a significant advancement in the field of radical oxidative coupling of ketones towards the synthesis of highly useful synthetic building blocks, such as 1,4-dicarbonyl compounds, and biologically important heterocyclic and carbocyclic compounds. Besides oxidative homo- and cross-coupling of enolates, other powerful methods involving direct C(sp3)–H functionalizations of ketones­ have emerged towards the synthesis of 1,4-dicarbonyl compounds. Moreover, direct α-C–H functionalization of ketones has also allowed an efficient access to carbocycles and heterocycles. Thi
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Ābele, E. "Oximes of Seven-Membered Heterocyclic Compounds Containing Two Heteroatoms." Latvian Journal of Chemistry 51, no. 1-2 (2012): 83–92. http://dx.doi.org/10.2478/v10161-012-0005-z.

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Oximes of Seven-Membered Heterocyclic Compounds Containing Two Heteroatoms Literature data concerning the synthesis and structure of diazepane, oxazepane and thiazepane oximes were reviewed. Synthesis of novel heterocycles from the oximes of seven-membered heterocycles containing two heteroatoms was described. Biological activity of oximes of seven-membered heterocycles with two heteroatoms was also reviewed.
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Gupta, Vivek Kumar, Baljeet Kaur, Amandeep Kaur, Amanpreet Kaur, and Monika Gupta. "Synthesis and Biological Evaluation of 1,3,4-Oxadiazolyl benzenesulphonyl benzimidazole derivatives." Indian Journal of Pharmaceutical and Biological Research 6, no. 02 (2018): 64–71. http://dx.doi.org/10.30750/ijpbr.6.2.10.

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Oxadiazoles are a class of heterocyclic aromatic chemical compound of azole family. Oxadiazole is five membered heterocycle having two carbons, two nitrogen, one oxygen and two double bonds. Oxadiazole exists in four isomeric forms depending upon the position of nitrogen atom in the ring. Benzimidazole is a heterocyclic aromatic compound. This bicyclic compound consists of fusion of benzene and imidazole. Benzimidazole may also be considered as cyclic analogues of imidines due to tautomerism effect. In the present study involves synthesis of1,3,4-oxadiazolyl benzenesulphonylbenzimidazole deriv
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Mohareb, Rafat, and Hanaa Hana. "Synthesis of progesterone heterocyclic derivatives of potential antimicrobial activity." Acta Pharmaceutica 58, no. 1 (2008): 29–42. http://dx.doi.org/10.2478/v10007-007-0043-3.

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Synthesis of progesterone heterocyclic derivatives of potential antimicrobial activityThe aim of this work was to synthesize steroidal heterocycles and to elucidate the potential role of these compounds as antimicrobial agents. The synthesis of steroidal heterocycles containing the pyrazole, isoxazole, thiazole, pyrane, pyridine, pyridazine, or benzopyrane ring attached to the pregnene nucleus is reported. Progesterone (1) reacts with dimethyl formamide dimethyl acetal to form enamine2. Heterocyclization of2with hydrazines, hydroxylamine, glycine, ethyl acetoacetate or cyanomethylene afforded
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Deng, Yongming, Qing-Qing Cheng, and Michael Doyle. "Asymmetric [3+3] Cycloaddition for Heterocycle Synthesis." Synlett 28, no. 14 (2017): 1695–706. http://dx.doi.org/10.1055/s-0036-1588453.

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Asymmetric syntheses of six-membered ring heterocycles are important research targets not only in synthetic organic chemistry but also in pharmaceuticals. The [3+3]-cycloaddition methodology is a complementary strategy to [4+2] cycloaddition for the synthesis of heterocyclic compounds. Recent progress in [3+3]-cycloaddition processes provide powerful asymmetric methodologies for the construction of six-membered ring heterocycles with one to three heteroatoms in the ring. In this account, synthetic efforts during the past five years toward the synthesis of enantioenriched six-membered ring hete
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Journal, Baghdad Science. "Synthesis of some Heterocyclic Compounds Derived from." Baghdad Science Journal 10, no. 3 (2013): 525–36. http://dx.doi.org/10.21123/bsj.10.3.525-536.

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The 4-(?-bromo acetyl)-4?-toluene sulfonanilide (2) was used as key intermediate to synthesize new heterocyclic compounds. This bromo compound was synthesized via sulfonation of amino group of p-amino acetophenone using Hinsburg method with 4-toluene sulfonyl chloride to form 4-acetyl-4?-toluene sulfonanilide (1) which is used as a starting material in this work. This compound was brominated to yield compound (2) which is used as a precursor to synthesize new five and seven membered heterocyclic compounds such as substituted 1,3-oxazoles (3,4), 1,3-thiazole derivatives (5-7), thiourea compound
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Dissertations / Theses on the topic "Synthesis. heterocyclic compounds"

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Wilson, Jennifer M. "Synthesis of biologically active heterocyclic compounds." Thesis, University of Glasgow, 2007. http://theses.gla.ac.uk/45/.

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More than 11 million people worldwide are diagnosed with cancer every year. New cancer drugs are required that are more effective and selective. Nitrogen mustard alkylating agents crosslink DNA inhibiting transcription and replication. Use of the mustard pharmacophore as part of a macrocycle allows metal complexation and produces a prodrug. Hypoxic tumour cells have increased concentrations of reductase enzymes which could lead to reduction of the complex in situ and release of a cytotoxic drug. Human African Trypanosomiasis is commonly known as Sleeping Sickness and affects over 36 countries
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Jamalis, Joazaizulfazli. "Synthesis of heterocyclic containing oxygen compounds." Thesis, University of Bristol, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.529847.

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Emans, John. "Synthesis of novel heterocyclic polymers." Thesis, University of St Andrews, 1987. http://hdl.handle.net/10023/15299.

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This work details the synthesis, characterisation and fabrication of a range of copolyesters, containing various angular disrupters, especially disubstituted 2,5-diphenyl- -1,3,4-oxadiazoles. These disrupters were incorporated into the polymers, to reduce the temperature at which the polymers may be processed, to enable their fabrication into fibres. The majority of the polymers prepared were found to be liquid crystalline. However, if the angular disrupter content of the polymer was high, it was found that the resultant polymers were non-liquid crystalline. The polymers were prepared by a mel
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李安怡 and On-yi Lee. "Synthesis of heterocycles via phenylseleno group transfer radical cyclization and chemoselective reductive amination promoted by InCl3." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B3955756X.

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Leu, Chao-Wei Chemistry Faculty of Science UNSW. "Synthesis of heterocyclic analogues of phytoestrogens." Publisher:University of New South Wales. Chemistry, 2008. http://handle.unsw.edu.au/1959.4/40824.

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The pyrrolo[3,2,1-ij]quinolin-6-one ring system was synthesised from 3-aryl-4,6-dimethoxyindoles and 2,3-disubstituted-4,6-dimethoxyindoles. The reaction of 4,6-dimethoxyindoles under Friedel-Crafts or Vilsmeier-Haack acylation gave the 2- and 7-indolyldeoxybenzoins in good yield. Cyclisation of 7-indolyldeoxybenzoins with N,N-dimethylformamide dimethyl acetal as a one carbon reagent gave the pyrroloquinolin-6-ones in high yield. Reduction of pyrroloquinolin-6-ones with hydrogen gas and 10% palladium on carbon or lithium aluminium hydride yielded the dihydropyrroloquinolin-6-ones. Demethylatio
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Burnett, Duane Arthur. "Synthesis of nitrogen containing heterocycles /." The Ohio State University, 1986. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487264603219377.

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Stewart, Lesley Ann. "Synthesis of heterocyclic compounds as potential anticancer agents." Thesis, University of Glasgow, 1996. http://theses.gla.ac.uk/4936/.

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Taher, Abutariq. "Novel cyclisations of nitro-compounds for heterocyclic synthesis." Thesis, Loughborough University, 2001. https://dspace.lboro.ac.uk/2134/34705.

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The research described in this thesis is aimed at developing novel methods of synthesis for heterocyclic compounds, in particular cyclisation reactions involving the nitro functional group. The first chapter describes investigations into the Wallach imidazole synthesis. A number of chloroimidazoles were prepared, but the possible extension to highly functionalised imidazoles proved elusive. The second chapter describes studies on the successful conversion of nitroimidazolyl malonates 1 into imidazo[4,5-c]isoxazoles 2, Scheme 1. Related cyclisations are described in chapter three and the thioph
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Khan, Musharraf Naveed. "Synthesis of different heterocyclic compounds of pharmaceutical relevance." Thesis, University of Huddersfield, 2013. http://eprints.hud.ac.uk/id/eprint/19503/.

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This thesis describes the synthesis of different cyclic imines and the exploration of their reactivity with cyclopropenones and 1,3-dipoles,as well as an investigation of the chemistry of the products. The synthesis of biologically and pharmaceutically important heterocyclic natural product analogues, such as the pyrroloazepines, indolizidines and pyrrolizidines has been achieved using a cycloaddition reaction between cyclic imidates and cyclopropenones. A new route to pyridines has been developed using the generation of a proposed 3-azacyclopentadienone as the key step. The 3-azacyclopentadie
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Shirtcliff, Laura Donnell. "'Coarctate' cyclizations : applications to heterocycle synthesis /." view abstract or download file of text, 2006. http://proquest.umi.com/pqdweb?did=1188876631&sid=1&Fmt=2&clientId=11238&RQT=309&VName=PQD.

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Thesis (Ph. D.)--University of Oregon, 2006.<br>Typescript. Includes vita and abstract. Includes bibliographical references (leaves 336-357). Also available for download via the World Wide Web; free to University of Oregon users.
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Books on the topic "Synthesis. heterocyclic compounds"

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Ellis, G. P. Synthesis of fused heterocycles. Wiley, 1987.

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Fluorinated heterocyclic compounds: Synthesis, chemistry, and applications. Wiley, 2009.

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Patel, Ramesh. Triazines: Synthesis, applications, and toxicity. Nova Science Publishers, 2011.

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Ellis, G. P. Synthesis of fused heterocycles : Part 2. Wiley, 1992.

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A, Tyrell John, ed. Fundamentals of heterocyclic chemistry: Importance in nature and in the synthesis of pharmaceuticals. Wiley, 2010.

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Vicario, Jose L., Dolores Badia, and Luisa Carrillo. New methods for the asymmetric synthesis of nitrogen heterocycles 2005. Research Signpost, 2005.

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Rusanov, A. L. Aromatic polyethers based on heterocyclic monomers. Nova Science Publishers, 2010.

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Ellis, G. P. Synthesis of fused heterocycles. Wiley, 1987.

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1962-, El-Nemr Ahmed, ed. Synthesis of naturally occurring nitrogen heterocycles from carbohydrates. Blackwell Pub., 2005.

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Diana, Patrizia. Biosynthesis of heterocycles: From the isolation to gene cluster. Wiley, 2015.

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Book chapters on the topic "Synthesis. heterocyclic compounds"

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Tabaković, Ibro. "Anodic synthesis of heterocyclic compounds." In Topics in Current Chemistry. Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/3-540-61454-0_71.

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Rathore, Deepshikha, Geetanjali, and Ram Singh. "Enzyme-Mediated Synthesis of Heterocyclic Compounds." In Advances in Green Synthesis. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-67884-5_16.

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Yamamoto, Yoshihiko, and Kenji Itoh. "Ruthenium-Catalyzed Synthesis of Heterocyclic Compounds." In Ruthenium Catalysts and Fine Chemistry. Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/b94646.

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Joule, J. A., K. Mills, and G. F. Smith. "Saturated and partially unsaturated heterocyclic compounds: reactions and synthesis." In Heterocyclic Chemistry. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4899-3222-8_26.

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Miles, Dillon H., and F. Dean Toste. "Enantioselective Gold-Catalyzed Synthesis of Heterocyclic Compounds." In Topics in Heterocyclic Chemistry. Springer International Publishing, 2015. http://dx.doi.org/10.1007/7081_2015_5003.

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Hoffmann, Reinhard W., Achim Hense, Ingo Münster, Jochen Krüger, David Brückner, and Vincent J. Gerusz. "Synthesis of Heterocyclic Compounds by Allylboration Reactions." In ACS Symposium Series. American Chemical Society, 2001. http://dx.doi.org/10.1021/bk-2001-0783.ch012.

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Norman, Richard, and James M. Coxon. "The synthesis of five-and six-membered heterocyclic compounds." In Principles of Organic Synthesis. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-2166-8_21.

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Barba, Fructuoso. "Electrosynthesis of Heterocyclic Compounds and Other Alternative Electrosynthetic Processes." In Novel Trends in Electroorganic Synthesis. Springer Japan, 1998. http://dx.doi.org/10.1007/978-4-431-65924-2_82.

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Race, Nicholas J., and John F. Bower. "Synthesis of Heteroaromatic Compounds by Alkene and Enyne Metathesis." In Topics in Heterocyclic Chemistry. Springer International Publishing, 2015. http://dx.doi.org/10.1007/7081_2015_145.

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Quirós, María Teresa, and María Paz Muñoz. "Synthesis of Heterocyclic Compounds via Gold-Catalysed Enyne Rearrangements." In Topics in Heterocyclic Chemistry. Springer International Publishing, 2015. http://dx.doi.org/10.1007/7081_2015_5004.

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Conference papers on the topic "Synthesis. heterocyclic compounds"

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El Fattah, M. E. Abd, H. H. Abd Allah, and A. H. Soliman. "Synthesis and Biological Activity of Some New Heterocyclic Compounds." In The 14th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2010. http://dx.doi.org/10.3390/ecsoc-14-00495.

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Redda, Kinfe Ken, Madhavi Gangapuram, Mohammad A. Ghaffari, Suresh Eyunni, Nelly Mateeva, and Bereket Mochona. "Abstract 2229: Synthesis of heterocyclic compounds as anticancer agents." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-2229.

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Stanovnik, Branko. "3-Dimethylaminopropenoates and Related Compounds in the Synthesis of Heterocyclic Systems and Heterocyclic Amino Acids." In The 4th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2000. http://dx.doi.org/10.3390/ecsoc-4-01783.

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Glukhacheva, Vera, and Sergey Ilꞌyasov. "SYNTHESIS AND PROPERTIES OF NITRO DERIVATIES OF HETEROCYCLIC ANTRACENES." In Chemistry of nitro compounds and related nitrogen-oxygen systems. LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m729.aks-2019/97-99.

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Drokin, R., D. Gazizov, D. Tiufiakov, et al. "POTASSIUM SALTS OF NITROCARBONYL COMPOUNDS IN THE SYNTHESIS OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS." In Chemistry of nitro compounds and related nitrogen-oxygen systems. LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m749.aks-2019/187-189.

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AL-Khazraji, Shaima Ibraheem Chyad. "Synthesis and characterization of some heterocyclic compounds derived from 2-mercapto benzothiazole." In INTERNATIONAL CONFERENCE OF NUMERICAL ANALYSIS AND APPLIED MATHEMATICS ICNAAM 2019. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0027534.

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Obaid, Ehab K., Rahmah H. Abdullah, Hussein Abdulkadim Hasan, Najlaa N. Hussein, Maha A. Khalaf, and Ali Jabbar Radhi. "Synthesis and study biological activity of new heterocyclic compounds based on sugar." In INTERNATIONAL CONFERENCE OF NUMERICAL ANALYSIS AND APPLIED MATHEMATICS ICNAAM 2019. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0027867.

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Azeez, Hashim, and Bana Abdulrahman. "Synthesis and Spectroscopic Characterization of a New Series of Thiazolidin-4-One Compounds from Heterocyclic Schiff Bases." In 2018 International Conference on Pure and Applied Science. Koya University, 2018. http://dx.doi.org/10.14500/icpas2018.ach77.

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Azeez, Hashim J., and Roshna Bahram. "Synthesis and spectroscopic identification of a new series of 2-iminothia-zolidin-4-one compounds from aromatic heterocyclic primary amines." In 6TH INTERNATIONAL CONFERENCE AND WORKSHOPS ON BASIC AND APPLIED SCIENCES. Author(s), 2017. http://dx.doi.org/10.1063/1.5004296.

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Hussein, Ola, Feras Alali, Ala-Eddin Al Moustafa, and Ashraf Khalil. "Design, Synthesis and Biological Evaluation of Novel Chalcone Analogs as Potential Therapeutic Agents for Castration-Resistant Prostate Cancer." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0179.

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Prostate cancer (PCa) is the second most frequently diagnosed malignancy, as well as a leading cause of cancer-related mortality in men globally. Despite the initial response to hormonal targeted therapy, the majority of patients ultimately progress to a lethal form of the disease, termed as castration-resistant prostate cancer (CRPC), which currently lacks curative therapeutic options and is associated with poor prognosis. Therefore, the development of novel treatment modalities for PCa is urgently needed. Chalcones, also known as 1,3-diphenyl-2-propen-1-ones, are among the highly attractive
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