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Relevant bibliographies by topics / Synthesis of isoxazoles

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Dissertations / Theses

Academic literature on the topic 'Synthesis of isoxazoles'

Author: Grafiati

Published: 4 June 2021

Last updated: 13 February 2022

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Dissertations / Theses on the topic "Synthesis of isoxazoles"

1

Knight, Julian Gary. "Diphenylphosphinoylalkyk isoxazoles and isoxazolines." Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306451.

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2

Tout, Jaki. "The synthesis and reactions of alkenyl isoxazoles and isoxazolines." Thesis, University of Edinburgh, 1993. http://hdl.handle.net/1842/14563.

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Four vinyl-isoxazoles and -2-isoxazolines have been synthesised as potential monomers for polymerisation studies. 5-Phenyl-3-vinylisoxazole was prepared in 38% overall yield by a sequence involving cycloaddition of ethoxycarbonyl-formonitrile oxide to phenylacetylene and then reduction of the resulting 3-carbethoxyisoxazole to the aldehyde using di-isobutylaluminium hydride. In the final stage Wittig olefination of the formyl-isoxazole afforded the target compound. 5-Phenyl-3-vinylisoxazole (17%) and 5-phenyl-3-vinyl-2-isoxazoline (26%) were synthesised similarily from ethyl propiolate & benzo

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3

Blackburn, Jack. "The synthesis, attempted synthesis and applications of 1,2,4-oxadiazoles and isothiazolo-isoxazoles." Thesis, University of Huddersfield, 2014. http://eprints.hud.ac.uk/id/eprint/26888/.

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4

Duffy, Kevin James. "Studies on the synthesis and reactivity of fused 3,4-isoxazoles." Thesis, University of Edinburgh, 1993. http://hdl.handle.net/1842/13734.

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This thesis is concerned with the synthesis of various fused, 3,4-isoxazoles by the thermal cyclisation of 2-nitroaryl and 2-nitroheteroaryl acetic acid derivatives and the exploitation of the uses of these compounds in heterocyclic synthesis by their reduction to afford 2-aminoaryl and heteroaryl ketones followed by the annulation of these latter derivatives. Heating solutions of 2-(3-nitropyrid-2-yl)propanedioate esters under reflux in inert solvents afforded isoxazolo[4,3-b]pyridine-3-carboxylate derivatives. The successful application of this novel synthesis on a large scale was crucially

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5

Kivrak, Arif. "Development Of New Methods For The Synthesis Of Pyrazoles, 4-iodopyrazoles, Isoxazoles And 1,2,4-oxadiazoles." Phd thesis, METU, 2011. http://etd.lib.metu.edu.tr/upload/12612945/index.pdf.

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Synthesis of five-membered heteroaromatic compounds such as pyrazoles, isoxazoles and 1,2,4-oxadiazoles are important for pharmaceutical industry and material science due to their applications. Although there are many methods to prepare such compounds, new variants continue to appear since they exhibit a wide range of biological and medicinal activities. In this thesis, new methods were developed for the synthesis of 4-iodopyrazoles, pyrazoles, isoxazoles, 1,2,4-oxadiazoles and/or 1,2,4-oxadiazepines. In the first part of the study, electrophilic cyclization of &alpha<br>,&beta<br>-alkynic hy

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6

FALCOU, SERGE, and André Pierre Joseph Rassat. "Utilisation des isoxazoles en synthese : approche de la synthese de la phyllanthocine." Paris 6, 1995. http://www.theses.fr/1995PA066314.

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La synthese de la phyllanthocine et en particulier du systeme spirocetal bicyclique 6,5 fait intervenir la condensation aldolique de l'enolate du 3-acetylisoxazole sur un hydroxyaldehyde methyle. Apres la mise au point de la synthese de cet isoxazole inconnu, et suite a la mauvaise reactivite de l'enolate de cet isoxazole, une modification de la strategie de synthese nous a conduit a realiser un umpolung en condensant un alcynure sur le 3-carbomethoxyisoxazole. Cette strategie permet d'acceder au produit d'aldolisation precedemment souhaite par addition conjuguee diastereoselective d'un hemiac

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7

Moschref, Said-Nadjib. "Synthese und Umlagerung von mono-metallierten Bisallylethersystemen und die Synthese von mono-metallierten Isoxazolen." [S.l. : s.n.], 1999. http://deposit.ddb.de/cgi-bin/dokserv?idn=962341290.

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8

Lanson, Marc. "Isoxazoles polyalkyles : synthese, etude structurale et comportement en milieu biologique." Paris 6, 1987. http://www.theses.fr/1987PA066468.

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9

Michaud, Thierry. "Synthese d'heterocycles azotes enatiomeriquement purs (aziridines, azetidines, isoxazoles) au depart de monosaccharides." Clermont-Ferrand 2, 1995. http://www.theses.fr/1995CLF21711.

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Un axe important de la chimie des glucides est leur utilisation comme source de chiralite dans la synthese de molecules a proprietes biologiques potentielles. Notre objectif a ete la synthese d'azetidines polyhydroxylees substituees en 2 et 3, enantiomeriquement pures, au depart de monosaccharides. Des ditosylates en 4,6 ont ete prepares en quatre etapes au depart des d-gluco- et d-mannopyranose par acetalisation, c-alkylation, hydrolyse et tosylation. Dans la serie du d-glucopyranose l'action d'amines primaires (methyl-, benzyl-, et tertbutylamine) sur les derives ditosyles permet d'acceder,

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10

Fritz, Martina Désirée. "p38 MAP Kinase Inhibitoren : Synthese, Analytik und biologische Testung substituierter Isoxazole /." [S.l. : s.n.], 2004. http://www.gbv.de/dms/bs/toc/39191703X.pdf.

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