Relevant bibliographies by topics / Synthesis of pyrroles

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Synthesis of pyrroles'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Synthesis of pyrroles"

1

Mohamed, Mosaad, Ramdan El-Domany, and Rania Abd El-Hameed. "Synthesis of certain pyrrole derivatives as antimicro-bial agents." Acta Pharmaceutica 59, no. 2 (2009): 145–58. http://dx.doi.org/10.2478/v10007-009-0016-9.

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Synthesis of certain pyrrole derivatives as antimicro-bial agentsIn an effort to establish new pyrroles and pyrrolo[2,3-d] pyrimidines with improved antimicrobial activity we report here the synthesis andin vitromicrobiological evaluation of a series of pyrrole derivatives. A series of new 2-aminopyrrole-3-carbonitriles (1a-d) were synthesized from the reaction of benzoin, primary aromatic amines and malononitrile, from which a number of pyrrole derivatives (2a-dto5a-d) and pyrrolo[2,3-d]pyrimidines (6a-dto10a, d) were synthesized. Thein vitroantimicrobial testing of the synthesized compounds
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2

Quiclet-Sire, Béatrice, and Samir Zard. "Convergent Routes to Pyrroles Exploiting the Unusual Radical Chemistry of Xanthates – An Overview." Synlett 28, no. 20 (2017): 2685–96. http://dx.doi.org/10.1055/s-0036-1590809.

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Convergent routes to a variety of pyrroles involving radical additions of xanthates are described. Emphasis is placed on reactions leading to the formation of 1,4-diketones or 1,4-ketoaldehydes or their synthetic equivalents, which can then be condensed with ammonia or primary amines in a variation of the classical Paal–Knorr synthesis of pyrroles. The modification of pyrroles by direct radical addition is also discussed.1 Introduction2 Earlier Routes to Pyrroles3 The Xanthate Radical Addition–Transfer Process4 Application to Pyrrole Synthesis5 Further Variations6 Direct Modification of Existi
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Iqbal, Sarosh, Hina Rasheed, Rabiya Javed Awan, Ramsha Javed Awan, Asma Mukhtar, and Mark G. Moloney. "Recent Advances in the Synthesis of Pyrroles." Current Organic Chemistry 24, no. 11 (2020): 1196–229. http://dx.doi.org/10.2174/1385272824999200528125651.

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: Pyrroles are the most prevalent heterocyclic compounds, which are present as the basic cores in many natural products, such as vitamin B12, bile pigments like bilirubin and biliverdin, the porphyrins of heme, chlorophyll, chlorins, bacteriochlorins, and porphyrinogens. The biological activities of compounds having pyrrole analogs include antimicrobial (antibacterial, antifungal), anti-cancer (anti-cytotoxic, antimitotic), anti-tumor, anti-hyperlipidemic, anti-depressant, anti-inflammatory, antihyperglycemic, antiproliferative, anti-HIV and anti-viral activities. Accordingly, significant atte
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Ta, Daniel D., Jeanne M. Favret, and Sergei V. Dzyuba. "Facile Synthesis of Pyrrolyl-Containing Semisquaraines in Water as Precursors for Non-Symmetric Squaraines." Compounds 3, no. 1 (2022): 17–26. http://dx.doi.org/10.3390/compounds3010002.

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One-step reactions between squaric acid and pyrroles, such as 3-ethyl-2,4-dimethyl-pyrrole and 1,2,5-trimethylpyrrole, in water provide the corresponding pyrrol-2-yl- and pyrrol-3-yl-containing semisquaraines in high yields. These semisquaraines serve as useful precursors for the synthesis of various non-symmetric pyrrole-containing squaraine dyes.
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Gao, Meng, Wenting Zhao, Hongyi Zhao, Ziyun Lin, Dongfeng Zhang, and Haihong Huang. "An efficient and facile access to highly functionalized pyrrole derivatives." Beilstein Journal of Organic Chemistry 14 (April 20, 2018): 884–90. http://dx.doi.org/10.3762/bjoc.14.75.

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A straightforward and one-pot synthesis of pyrrolo[3,4-c]pyrrole-1,3-diones via Ag(I)-catalyzed 1,3-dipolar cycloaddition of azomethine ylides with N-alkyl maleimide, followed by readily complete oxidation with DDQ, has been successfully developed. Further transformation with alkylamine/sodium alkoxide alcohol solution conveniently afforded novel polysubstituted pyrroles in good to excellent yields. This methodology for highly functionalized pyrroles performed well over a broad scope of substrates. It is conceivable that this efficient construction method for privileged pyrrole scaffolds could
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Mateev, Emilio, Ali Irfan, Alexandrina Mateeva, Maya Georgieva, and Alexander Zlatkov. "Microwave-assisted organic synthesis of pyrroles (Review)." Pharmacia 71, no. () (2024): 1–10. https://doi.org/10.3897/pharmacia.71.e119866.

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The detection of pyrrole rings in numerous organic compounds with various pharmacological activities, emphasizes its huge importance in medicinal chemistry. Thus, the synthesis of pyrroles continues to arouse interest and Paal-Knorr condensation is considered to be the main synthetic route. A significant advance has been made since the MW activation was introduced in the organic synthesis which can be confirmed with the rapid growth of the published papers on that topic. Microwave irradiation is gaining popularity since faster reaction time, higher yields, easier work-up and reduced energy inp
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Menéndez, J., Marco Leonardi, Verónica Estévez, and Mercedes Villacampa. "The Hantzsch Pyrrole Synthesis: Non-conventional Variations and Applications of a Neglected Classical Reaction." Synthesis 51, no. 04 (2018): 816–28. http://dx.doi.org/10.1055/s-0037-1610320.

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Pyrrole is one of the most important one-ring heterocycles because of its widespread presence in natural products and unnatural bioactive compounds and drugs in clinical use. The preparation of pyrroles by reaction between primary amines, β-dicarbonyl compounds, and α-halo ketones, known as the Hantzsch pyrrole synthesis, is reviewed here for the first time. In spite of its age and its named reaction status, this method has received little attention in the literature. Recent work involving the use of non-conventional conditions has rejuvenated this classical reaction and this is emphasized in
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8

Miranda-Sánchez, Diter, Carlos H. Escalante, Dulce Andrade-Pavón, et al. "Pyrrole-Based Enaminones as Building Blocks for the Synthesis of Indolizines and Pyrrolo[1,2-a]pyrazines Showing Potent Antifungal Activity." Molecules 28, no. 20 (2023): 7223. http://dx.doi.org/10.3390/molecules28207223.

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As a new approach, pyrrolo[1,2-a]pyrazines were synthesized through the cyclization of 2-formylpyrrole-based enaminones in the presence of ammonium acetate. The enaminones were prepared with a straightforward method, reacting the corresponding alkyl 2-(2-formyl-1H-pyrrol-1-yl)acetates, 2-(2-formyl-1H-pyrrol-1-yl)acetonitrile, and 2-(2-formyl-1H-pyrrol-1-yl)acetophenones with DMFDMA. Analogous enaminones elaborated from alkyl (E)-3-(1H-pyrrol-2-yl)acrylates were treated with a Lewis acid to afford indolizines. The antifungal activity of the series of substituted pyrroles, pyrrole-based enaminon
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Palmieri, Alessandro, and Marino Petrini. "Synthesis and practical applications of 2-(2-nitroalkyl)pyrroles." Organic & Biomolecular Chemistry 18, no. 24 (2020): 4533–46. http://dx.doi.org/10.1039/d0ob00956c.

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Two main approaches can be designed for the synthesis of 2-(2-nitroalkyl)pyrroles using nitroalkenes or nitroalkanes in the reaction with pyrrole derivatives. The obtained nitroalkyl pyrroles can be converted into various bioactive compounds.
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Gharib, Ali, Manouchehr Jahangir, and J. Scheeren. "Novel catalytic method synthesis of calix[4]pyrroles using Preyssler and Wells-Dawson heteropolyacids." Polish Journal of Chemical Technology 13, no. 2 (2011): 70–73. http://dx.doi.org/10.2478/v10026-011-0027-4.

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Novel catalytic method synthesis of calix[4]pyrroles using Preyssler and Wells-Dawson heteropolyacids A catalytic synthesis of calix[4]pyrroles and N-confused calix[4]pyrroles by reaction of dialkyl or cycloalkyl ketones with pyrrole was performed using Preyssler, sodium30-tungsto pentaphosphate, [NaP5W30O110]14- and Wells-Dawson heteropolyacids as acidic catalysts. The process occurred under mild, eco-friendly and environmental friendly conditions and as a reusable, green catalyst at room temperature for 6 hours. The results showed that the yield for this synthesis is excellent with the use o
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Dissertations / Theses on the topic "Synthesis of pyrroles"

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Ottaway, Carol Jean. "Synthesis of carbapenams from pyrroles." Thesis, University of Liverpool, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283487.

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Armitage, Georgina Kate. "The Zav'yalov pyrrole synthesis revisited : some derivatives of 3-hydroxy- and 3-amino-pyrroles." Thesis, University of Huddersfield, 2017. http://eprints.hud.ac.uk/id/eprint/34175/.

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The objective of this study was to investigate the acylative-cyclisation-decarboxylation reactions of enamino acids derived from 1,3-difunctional compounds. Remarkably little is known regarding the generality of these variants of the Zav’yalov pyrrole synthesis, despite their considerable scope for the synthesis of functionalised pyrroles. The cyclisation of diethyl 2-(1-carboxyalkylaminomethylene)malonates provided access to a range of 5-(un)substituted-4-acetoxypyrrole-3-carboxylates. However, in some instances the corresponding 4-ethoxypyrrole-3-carboxylates also accounted for up to 20% of
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Voro, Tevita N. "Synthesis of potentially biologically active indoles and pyrroles." Thesis, University of East Anglia, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.254485.

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Kelly, James Michael. "The design and synthesis of conformationally restrained analogues of porphobilinogen." Thesis, University of Cambridge, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.609187.

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Chiu, Chung Wai-ling Margaret. "The synthesis and reactions of 3, 5-diaryl-2, 2-bis(ethoxycarbonyl)-2H-pyrroles /." [Hong Kong : University of Hong Kong], 1986. http://sunzi.lib.hku.hk/hkuto/record.jsp?B12344916.

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李思明 and Sze-ming Lee. "An investigation into novel synthetic routes for 3h-pyrroles." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1989. http://hub.hku.hk/bib/B31209257.

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Mezlova, Marie. "Benzofused thieno[3,2-b]pyrroles-synthesis, electrochemical and spectral behaviour." Paris 7, 2005. http://www.theses.fr/2005PA077212.

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This thesis deals with the synthesis of novel 1,4-diheteropentalene compounds, especially 4H-thieno[3,2-b]indoles and 1H-benzothieno[3,2-b]pyrrole, and the investigation of their electropolymerization. The aim was to prepare new conducting polymers and to determine how the structure of the monomer influences their electrochemical and spectral properties. The investigation can be subdivided into four parts. 1. In the context of the research on 1,4-diheteropentalenes performed in our laboratory in recent years, I have designed and prepared a series of novel thienoindoles and the isomeric benzoth
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Hansson, Mats. "Tetrapyrrole synthesis in Bacillus subtilis." Lund : Dept. of Microbiology, Lund University, 1994. http://books.google.com/books?id=pJBqAAAAMAAJ.

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楊小雯 and Siu-man Yeung. "The synthesis and reactions of 3H-pyrroles bearing methyl and aryl groups." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1991. http://hub.hku.hk/bib/B31210119.

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Sun, Qingqing. "Aryl and Super Aryl-Extended Calix[4]pyrroles: Synthesis and Applications." Doctoral thesis, Universitat Rovira i Virgili, 2021. http://hdl.handle.net/10803/672268.

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Aquesta tesi doctoral descriu el disseny i la síntesi d’una sèrie de receptors supramoleculars que presenten cavitats aromàtiques polars. Els receptors preparats inclouen receptors organometàl·lics, contenidors moleculars solubles en aigua, caixes moleculars basades en enllaços de coordinació i metal·lo-cavitands. S’han seleccionat unitats de calix[4]pirrole aril i super-aril estesos (AEC[4]P i SAE-C[4]P) com a components principals. S’han estudiat les propietats de reconeixement molecular dels receptors sintètics amb sals de clorur de tetraalquilamoni, així com de molècules polars neutres, en
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Books on the topic "Synthesis of pyrroles"

1

Voro, Tevita N. Synthesis of potentially biologically active indoles and pyrroles. Universityof East Anglia, 1990.

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M, Jordan P., ed. Biosynthesis of tetrapyrroles. Elsevier, 1991.

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Elsadig, Hwaida Misbah. Synthesis of pyrrolo[2,1-c][1,4]benzodiazepine peptoid oligomer libraries. [University of Portsmouth], 2000.

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Kawamoto, Yusuke. Synthesis and Biological Evaluation of Pyrrole–Imidazole Polyamide Probes for Visualization of Telomeres. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-6912-4.

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Gregson, Stephen John. Design, synthesis and evaluation of novel C2-unsaturated pyrrolo[2,1-c][1,4]benzodiazepines. University of Portsmouth, School of Pharmacy and Biomedical Sciences, 1998.

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Roberts, David. The synthesis of pyrrolo[4,3,2-de]quinolines and approaches towards hinckdentine A and apparacine. University of Manchester, 1996.

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Rehn, Carsten. Theoretische Studien zur DNA-Interkalation von Anthrachinon-, 9-Aminoacridin-, Isochinolin- und Pyrrolo-carbazol-1,3-dion-Derivaten sowie Synthese von Pyrrolo-carbazol-1,3-dionen. [s.n.], 1995.

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Thompson, Andrew Spencer. Design, synthesis and evaluation of covalent-binding DNA-interactive ligands based on pyrrolo[2,1-c][1,4]benzodiazepines. University of Portsmouth, School of Pharmacy and Biomedical Sciences, 1992.

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Corcoran, Kathryn Elizabeth. Synthetic approaches to C-ring unsaturated DNA cross-linking pyrrolo[2,1-c][1,4]benzodiazepine dimers. University of Portsmouth, School of Pharmacy and Biomedical Sciences, 1998.

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Jones, Gary B. Design, synthesis and evaluation of DNA-binding oxazolo[2,3-c][1,4] benzodiazepines and pyrrolo[2,1-c][1,4] benzodiazepines. Portsmouth Polytechnic, School of Pharmacy and Biomedical Sciences, 1991.

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Book chapters on the topic "Synthesis of pyrroles"

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Addor, R. W., T. J. Babcock, B. C. Black, et al. "Insecticidal Pyrroles." In Synthesis and Chemistry of Agrochemicals III. American Chemical Society, 1992. http://dx.doi.org/10.1021/bk-1992-0504.ch025.

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Kuhn, D. G., V. M. Kamhi, J. A. Furch, et al. "Insecticidal Pyrroles." In Synthesis and Chemistry of Agrochemicals III. American Chemical Society, 1992. http://dx.doi.org/10.1021/bk-1992-0504.ch026.

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Kameswaran, V., Roger W. Addor, and R. K. Ward. "Insecticidal Pyrroles." In Synthesis and Chemistry of Agrochemicals III. American Chemical Society, 1992. http://dx.doi.org/10.1021/bk-1992-0504.ch027.

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Joule, J. A., K. Mills, and G. F. Smith. "Pyrroles: reactions and synthesis." In Heterocyclic Chemistry. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4899-3222-8_13.

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Bean, Gerritt P. "The Synthesis of 1H-Pyrroles." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470187326.ch2.

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Larsen, Karina R., Kent A. Nielsen, Jonathan L. Sessler, and Jan O. Jeppesen. "Detection of Nitroaromatic Explosives Using Tetrathiafulvalene-Calix[4]pyrroles." In Organic Synthesis and Molecular Engineering. John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118736449.ch9.

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Ono, Noboru, and Tetsuo Okujima. "Synthesis of Pyrroles and Their Derivatives from Isocyanides." In Isocyanide Chemistry. Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527652532.ch11.

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Matsuoka, Junpei. "Total Synthesis of Dictyodendrins by the Gold-Catalyzed Cascade Cyclization of Conjugated Diynes with Pyrroles." In Total Synthesis of Indole Alkaloids. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-8652-1_2.

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Sammes, Michael P. "Physical and Theoretical Aspects, Synthesis, and Chemical Reactivity of 2H- and 3H-Pyrroles." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470187326.ch4.

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Arabpourian, K., and Farahnaz K. Behbahani. "Application of Starch in the Synthesis of N-substituted Pyrroles by a Simple and Green Route." In Greener Synthesis of Organic Compounds, Drugs and Natural Products. CRC Press, 2022. http://dx.doi.org/10.1201/9781003089162-11.

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Conference papers on the topic "Synthesis of pyrroles"

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Aquino, Estefania da C., Nilo Zanatta, Vanessa C. Gariboti, Helio G. Bonacorso, and Marcos A. P. Martins. "New strategy for the synthesis of 4-amine-2-trifluoromethyl pyrroles N-substituted." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_201383205848.

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Трофимов, Б., B. Trofimov, Н. Гусарова, and N. Gusarova. "The development of original methodologies of directed synthesis of le-Carbs their analogs and precursors base donacetylene and its derivatives." In Topical issues of translational medicine: a collection of articles dedicated to the 5th anniversary of the day The creation of a department for biomedical research and technology of the Irkutsk Scientific Center Siberian Branch of RAS. INFRA-M Academic Publishing LLC., 2017. http://dx.doi.org/10.12737/conferencearticle_58be81ec92d17.

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New reactions, which have been discovered and continue to be developed in A.E. Favorsky Irkutsk institute of chemistry SB RAS on the basis of acetylene, a product of oil, gas and coal processing and multi-faceted building block for organic synthesis, have been considered. These reactions provide for the shortest routes to construction of fundamental heterocyclic scaffolds (pyrroles, imidazoles, pyrazoles, indoles, pyridines, dihydropyridines, etc.) with desirable and optimum combination of functional pharmacophoric groups and fragments, which are responsible for antiviral (HIV, flu), antitumor
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Naimi-Jamal, Mohammad Reza, maryam hasani, and Leila Panahi. "MCM-41-SO3H as Heterogeneous Catalyst for One-pot Four Component Synthesis of Highly Substituted Pyrroles." In The 20th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2016. http://dx.doi.org/10.3390/ecsoc-20-c002.

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Jadhav, Bhagwat, Ramesh Yamgar, and Suraj N. Mali. "Synthesis and Anti-Tuberculosis Activity of Substituted 3,4-(dicoumarin-3-yl)-2,5-diphenyl Furans and Pyrroles." In International Electronic Conference on Applied Sciences. MDPI, 2022. http://dx.doi.org/10.3390/asec2022-13851.

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Golubenkova, Alexandra S., Nikita E. Golantsov, Alexey V. Varlamov, and Leonid G. Voskressensky. "Green synthesis of polysubstituted pyrroles through a domino sequence of aza-Claisen rearrangement/nucleophilic addition/oxidation/acylation." In ACTUAL PROBLEMS OF ORGANIC CHEMISTRY AND BIOTECHNOLOGY (OCBT2020): Proceedings of the International Scientific Conference. AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0069005.

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Otero, T. F., and J. Rodriguez. "Free solvent electropolymerization of pyrrole." In International Conference on Science and Technology of Synthetic Metals. IEEE, 1994. http://dx.doi.org/10.1109/stsm.1994.835317.

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Vernitskaya, T. V., O. N. Efimov, and A. B. Gavrilov. "Catalysis of pyrrole electropolymerization by tetrachloroferrate anion." In International Conference on Science and Technology of Synthetic Metals. IEEE, 1994. http://dx.doi.org/10.1109/stsm.1994.835355.

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Assis, Francisco F. de, Timothy J. Brocksom, and Kleber T. de Oliveira. "Synthesis of 3,4-dibromo-1H-pyrrole-2-carbaldehyde: a building block for preparation of tetrabromobacteriochlorins." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_2013913103524.

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Masuda, H., and K. Kaeriyama. "Electrochemical polymerization of pyrrole with water-soluble polymeric electrolytes." In International Conference on Science and Technology of Synthetic Metals. IEEE, 1994. http://dx.doi.org/10.1109/stsm.1994.835304.

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Haaland, Peter, and James Targove. "Flowing Afterglow Synthesis of Polythiophene Films." In Nonlinear Guided-Wave Phenomena. Optica Publishing Group, 1991. http://dx.doi.org/10.1364/nlgwp.1991.tue4.

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Polymers of aromatic heterocycles such as thiophene and pyrrole have been actively investigated for their promising electrical and optical characteristics. However the use of these materials in waveguide structures has been constrained by morphological and synthetic barriers. Specifically, larger oligomers are less soluble causing multiphase chemical kinetics and irregular morphology in the metal-catalyzed coupling syntheses.fi] Electrochemical preparation methods also produce grainy or fibrillar material, most probably because the heterogeneous boundary conditions on film growth change as ins
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Reports on the topic "Synthesis of pyrroles"

1

Allcock, Harry R., Jeffrey A. Dodge, Leon S. Van Dyke, and Charles R. Martin. Polyphosphazenes Bearing Polymerizable Pyrrole, Thiophene and Furan Side Groups: Synthesis and Chemical Oxidation. Defense Technical Information Center, 1992. http://dx.doi.org/10.21236/ada249747.

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Shu, Ching-Fong, and Mark S. Wrighton. Synthesis and Charge Transport Properties of Polymers Derived from Oxidation of 1-H-1'(6-pyrrol-1-yl)-hexyl-4,4'-bipyridinium. Defense Technical Information Center, 1988. http://dx.doi.org/10.21236/ada198070.

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[Studies of hydrogen-hydrogen and carbon-sulfur bond cleavage; Lewis acid modified molybdenum sulfide complexes; and Syntheses and reactions of pyrrole complexes]. Final report. Office of Scientific and Technical Information (OSTI), 1998. http://dx.doi.org/10.2172/650154.

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