Relevant bibliographies by topics / Synthesis of xanthone

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Synthesis of xanthone'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Synthesis of xanthone"

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Paraskevas, Konstantinos, Christos Iliopoulos-Tsoutsouvas, Eleftheria A. Georgiou, and Ioannis K. Kostakis. "5-Chloro-6-oxo-6H-xantheno[4,3-d]thiazole-2-carbonitrile." Molbank 2022, no. 4 (2022): M1489. http://dx.doi.org/10.3390/m1489.

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Xanthones and benzothiazoles are important classes of heterocyclic compounds with versatile biological activities. Herein, we describe a straightforward and scalable synthesis of 5-chloro-6-oxo-6H-xantheno[4,3-d]thiazole-2-carbonitrile, a thiazole-fused xanthone, via a six-step approach, using Appel’s salt for the synthesis of the thiazole ring. The thiazole-fused xanthone was fully characterized employing 1H and 13C NMR spectra, using direct and long-range heteronuclear correlation experiments (HMBC and HMQC).
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Lemos, Agostinho, Ana Sara Gomes, Joana B. Loureiro, et al. "Synthesis, Biological Evaluation, and In Silico Studies of Novel Aminated Xanthones as Potential p53-Activating Agents." Molecules 24, no. 10 (2019): 1975. http://dx.doi.org/10.3390/molecules24101975.

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Xanthone scaffold has been regarded as an attractive chemical tool in the search for bioactive molecules with antitumor activity, and in particular two xanthone derivatives, 12-hydroxy-2,2-dimethyl-3,4-dihydro-2H,6H-pyrano [3,2-b]xanthen-6-one (4) and 3,4-dimethoxy-9-oxo-9H-xanthene-1-carbaldehyde (5), were described as a murine double minute 2 (MDM2)-p53 inhibitor and a TAp73 activator, respectively. The xanthone 5 was used as a starting point for the construction of a library of 3,4-dioxygenated xanthones bearing chemical moieties of described MDM2-p53 inhibitors. Eleven aminated xanthones w
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Huang, Qing, Youyi Wang, Huaimo Wu, Man Yuan, Changwu Zheng, and Hongxi Xu. "Xanthone Glucosides: Isolation, Bioactivity and Synthesis." Molecules 26, no. 18 (2021): 5575. http://dx.doi.org/10.3390/molecules26185575.

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Xanthones are secondary metabolites found in plants, fungi, lichens, and bacteria from a variety of families and genera, with the majority found in the Gentianaceae, Polygalaceae, and Clusiaceae. They have a diverse range of bioactivities, including anti-oxidant, anti-bacterial, anti-malarial, anti-tuberculosis, and cytotoxic properties. Xanthone glucosides are a significant branch of xanthones. After glycosylation, xanthones may have improved characteristics (such as solubility and pharmacological activity). Currently, no critical review of xanthone glucosides has been published. A literature
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Singh, Dileep Kumar, та Mahendra Nath. "Synthesis and spectroscopic properties of β-triazoloporphyrin–xanthone dyads". Beilstein Journal of Organic Chemistry 11 (17 серпня 2015): 1434–40. http://dx.doi.org/10.3762/bjoc.11.155.

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A novel series of β-triazoloporphyrin–xanthone conjugates and xanthone-bridged β-triazoloporphyrin dyads has been synthesized in moderate to good yields through Cu(I)-catalyzed Huisgen 1,3-dipolar cycloaddition reaction of copper(II) 2-azido-5,10,15,20-tetraphenylporphyrin or zinc(II) 2-azidomethyl-5,10,15,20-tetraphenylporphyrin with various alkyne derivatives of xanthones in DMF containing CuSO4 and ascorbic acid at 80 °C. Furthermore, these metalloporphyrins underwent demetalation under acidic conditions to afford the corresponding free-base porphyrins in good to excellent yields. After suc
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Badiali, Camilla, Valerio Petruccelli, Elisa Brasili, and Gabriella Pasqua. "Xanthones: Biosynthesis and Trafficking in Plants, Fungi and Lichens." Plants 12, no. 4 (2023): 694. http://dx.doi.org/10.3390/plants12040694.

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Xanthones are a class of secondary metabolites produced by plant organisms. They are characterized by a wide structural variety and numerous biological activities that make them valuable metabolites for use in the pharmaceutical field. This review shows the current knowledge of the xanthone biosynthetic pathway with a focus on the precursors and the enzymes involved, as well as on the cellular and organ localization of xanthones in plants. Xanthone biosynthesis in plants involves the shikimate and the acetate pathways which originate in plastids and endoplasmic reticulum, respectively. The pat
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Mkounga, Pierre, Zacharias T. Fomum, Michèle Meyer, Bernard Bodo, and Augustin E. Nkengfack. "Globulixanthone F, a New Polyoxygenated Xanthone with an Isoprenoid Group and Two Antimicrobial Biflavonoids from the Stem Bark of Symphonia Globulifera¶." Natural Product Communications 4, no. 6 (2009): 1934578X0900400. http://dx.doi.org/10.1177/1934578x0900400613.

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Bioassay-guided fractionation of the stem bark of Symphonia globulifera has yielded three known xanthones, ugaxanthone (1), mbarraxanthone (2) and gentisein (3), two biflavonoid derivatives named GB2 (4) and manniflavanone GB3 (5), and one new polyoxygenated xanthone with an isoprenoid group, named globulixanthone F (6). The structures of these compounds were elucidated by means of spectroscopic methods. The spectral data of 1 and 2 are reported here for the first time, as well as the antimicrobial activity of globulixanthone F against a range of microorganisms. We also report the total synthe
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Bornadiego, Ana, Jesús Díaz, and Carlos F. Marcos. "Expeditious Multicomponent Synthesis of Xanthone Dimers." Proceedings 9, no. 1 (2018): 13. http://dx.doi.org/10.3390/ecsoc-22-05766.

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Xanthones are a type of compound widely found in many natural products from plants, fungi, and lichens and are considered privileged structures. Frequently, xanthones occur in nature as dimers, which often exhibit singular and potent biological effects. Although diverse methods for the synthesis of monomeric xanthones are known, dimeric xanthones remain synthetically challenging targets. Reported syntheses of dimeric xanthones are very scarce, and invariably involve a large number of synthetic steps. We have recently developed a multicomponent synthesis of xanthones starting from 3-carbonylchr
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Pinto, Madalena M. M., Andreia Palmeira, Carla Fernandes, et al. "From Natural Products to New Synthetic Small Molecules: A Journey through the World of Xanthones." Molecules 26, no. 2 (2021): 431. http://dx.doi.org/10.3390/molecules26020431.

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This work reviews the contributions of the corresponding author (M.M.M.P.) and her research group to Medicinal Chemistry concerning the isolation from plant and marine sources of xanthone derivatives as well as their synthesis, biological/pharmacological activities, formulation and analytical applications. Although her group activity has been spread over several chemical families with relevance in Medicinal Chemistry, the main focus of the investigation and research has been in the xanthone family. Xanthone derivatives have a variety of activities with great potential for therapeutic applicati
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Borzdziłowska, Paulina, and Ilona Bednarek. "Xanthones as natural compounds with a wide spectrum of biological activity." Postępy Higieny i Medycyny Doświadczalnej 72 (August 27, 2018): 767–80. http://dx.doi.org/10.5604/01.3001.0012.3277.

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One of the fields of research involving new substances with potential therapeutic effects is folk medicine. In indigenous cultures, including Far Eastern culture, medicine is based on beliefs and superstitions, passed down from generation to generation, concerning the effects of certain substances contained in plants, herbs or spices. Science very often uses traditional knowledge as a source of information. Observation of everyday life and customs of this culture became the starting point for this research on the plants of the family Clusiacaceae Lindl. Substances included in the different par
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Bedi, Pooja, Richa Gupta, Richa Gupta, Tanay Pramanik, and Tanay Pramanik. "SYNTHESIS AND BIOLOGICAL PROPERTIES OF PHARMACEUTICALLY IMPORTANT XANTHONES AND BENZOXANTHONE ANALOGS: A BRIEF REVIEW." Asian Journal of Pharmaceutical and Clinical Research 11, no. 2 (2018): 12. http://dx.doi.org/10.22159/ajpcr.2018.v11i2.22426.

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Xanthones are one of the biggest classes of compounds in natural product chemistry. A number of xanthones have been isolated from natural sources of higher plants such as fungi, ferns, and lichens. Synthetic analogs of xanthones have shown a large number of pharmacological properties such as antioxidant, anti-inflammatory, antidiabetics, antihistamine, antitumoral, antiulcer, and algicidal. Moreover, they also find usages in photodynamic therapy, laser technology, and dyes. This review lays stress on various solvents, catalyst and synthetic route for synthesis of xanthones, benzoxanthones anal
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Dissertations / Theses on the topic "Synthesis of xanthone"

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Cho, Woo Cheal. "Synthesis of caged Garcinia xanthone analogues." Diss., [La Jolla] : University of California, San Diego, 2009. http://wwwlib.umi.com/cr/ucsd/fullcit?p1469234.

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Thesis (M.S.)--University of California, San Diego, 2009.<br>Title from first page of PDF file (viewed October 13, 2009). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.
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Mancini, Michael. "Approaches to the synthesis of xanthone analogs of the anthracycline class of anticancer agents." Thesis, McGill University, 1985. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=72059.

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Several strategies outlining approaches to the synthesis of the heteroanthracyclinones 4-demethoxyxanthodaunomycinone and 4-demethoxyisoxanthodaunomycinone (7,8,9,10-tetrahydrobenzo(b)-6,7,9,11-tetrahydroxy-9-acetylxanthen-12 and 5-one) are described.<br>The condensation of tetralin 2-acetyl-5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthol with o-methoxybenzoic acid was investigated and useful large-scale syntheses of important 1,4-dimethoxy-substituted xanthone intermediates were developed.<br>Diels-Alder cycloaddition reaction between a xanthone-derived o-quinodimethane intermediate and an olefin
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Palmeira, Andreia Filipa dos Santos. "Design Synthesis and Evaluation of Xanthone Derivatives for Dual Activity: Antitumor and P-Glycoprotein Inhibition." Doctoral thesis, Faculdade de Farmácia da Universidade do Porto, 2010. http://hdl.handle.net/10216/63796.

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Palmeira, Andreia Filipa dos Santos. "Design Synthesis and Evaluation of Xanthone Derivatives for Dual Activity: Antitumor and P-Glycoprotein Inhibition." Tese, Faculdade de Farmácia da Universidade do Porto, 2010. http://hdl.handle.net/10216/63796.

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Johann, Laure. "Synthesis and mechanism of 1,4-naphthoquinones as turncoast inhibitors of disulfide reductases affecting the redox equilibrium of schistosomes and malaria parasites." Strasbourg, 2011. https://publication-theses.unistra.fr/restreint/theses_doctorat/2011/JOHANN_Laure_2011_ED222.pdf.

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Cette thèse décrit la synthèse et le mécanisme d'action de nouveaux agents antiparasitaires contre le paludisme et la schistosomiase, deux maladies infectieuses majeures causées respectivement par le protozoaire Plasmodium et l'helminthe Schistosoma mansoni. Chez ces parasites, l’équilibre rédox est maintenu par deux enzymes essentielles et identifiées comme cibles thérapeutiques, la glutathion réductase (GRs : humaine et parasitaire), et la thiorédoxine-glutathion réductase chez le ver (TGR). Des travaux précédents avaient permis l'identification de 3-benzyl-ménadiones antipaludiques, et de l
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Kelkar, Avijit S. "Novel syntheses of substituted xanthones." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B31238671.

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招桂鳳 and Kwei-fung Chiu. "Syntheses and chemistry of some xanthone derivatives." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1995. http://hub.hku.hk/bib/B31234768.

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Chiu, Kwei-fung. "Syntheses and chemistry of some xanthone derivatives /." Hong Kong : University of Hong Kong, 1995. http://sunzi.lib.hku.hk/hkuto/record.jsp?B17506633.

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Lam, Thanh T. "Synthesis and synthetic studies towards diterpenes, sesquiterpenoids, and the caged Garcinia xanthones." Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2007. http://wwwlib.umi.com/cr/ucsd/fullcit?p3274525.

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Thesis (Ph. D.)--University of California, San Diego, 2007.<br>Title from first page of PDF file (viewed October 3, 2007). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.
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Kotásková, Michaela [Verfasser]. "Synthesis of new xanthene derivatives / Michaela Kotásková." Mainz : Universitätsbibliothek Mainz, 2013. http://d-nb.info/1029903409/34.

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Books on the topic "Synthesis of xanthone"

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Mooney, Nichola Jane. Synthesis and properties of crown ethers incorporating Xanthene residues. University of Manchester, 1993.

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Hewitt, J. T. Synthetic Colouring Matters Dyestuffs Derived from Pyridine, Quinoline, Acridine and Xanthene. Creative Media Partners, LLC, 2022.

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Hewitt, J. T. Synthetic Colouring Matters Dyestuffs Derived from Pyridine, Quinoline, Acridine and Xanthene. Creative Media Partners, LLC, 2022.

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Hewitt, John Theodore. Synthetic Coloring Matters: Dyestuffs Derived From Pyridine, Quinoline, Acridine And Xanthene (1922). Kessinger Publishing, LLC, 2010.

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Book chapters on the topic "Synthesis of xanthone"

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Dakanali, Marianna, and Emmanuel A. Theodorakis. "Polyprenylated Phloroglucinols and Xanthones." In Biomimetic Organic Synthesis. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527634606.ch12.

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Zhang, Ji, and Yingjun Zhang. "Febuxostat (Uloric): A Xanthine Oxidase Inhibitor for the Treatment of Gout." In Innovative Drug Synthesis. John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781118819951.ch17.

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Demirkiran, Ozlem. "Erratum to Xanthones in Hypericum: Synthesis and Biological Activities." In Topics in Heterocyclic Chemistry. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/7081_2007_091.

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Somlai, Csaba, Peter Hegyes, Levente Nyerges, Botond Penke, and Wolfgang Voelter. "Design and synthesis of 3,9-substituted xanthene derivatives: Application for solid-phase synthesis." In Peptides 1992. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-1470-7_76.

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Veljović, Elma, Selma Špirtović-Halilović, Samija Muratović, et al. "Artificial Neural Network and Docking Study in Design and Synthesis of Xanthenes as Antimicrobial Agents." In IFMBE Proceedings. Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-4166-2_93.

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Scarpecci, Cristina, and Sara Consalvi. "Biological Activities of Synthetic Derivatives of Xanthones: An Update (2016-2020)." In Flavonoids and Phenolics. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815079098122010006.

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Natural xanthones are a class of secondary metabolites widely distributed in nature and with a broad spectrum of biological activities. Their scaffold is amenable to several modifications and has emerged as a “privileged structure” for drug development, representing a very attractive point for medicinal chemistry optimization. A combination of innovative synthetic methodologies and medicinal chemistry studies have provided several xanthone synthetic derivatives for different therapeutic purposes, including cancer, inflammation, Alzheimer’s disease (AD), cardiovascular and infectious diseases.
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Williams, A. C., and N. Camp. "Synthesis of 9-Xanthene-9-thiones from 9-Xanthen-9-ones via 9,9-Dichloro-9-xanthenes." In Six-Membered Hetarenes with One Chalcogen. Georg Thieme Verlag KG, 2003. http://dx.doi.org/10.1055/sos-sd-014-00745.

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Piōrko, A., C. C. Lee, and R. G. Sutherland. "(η6-XANTHENE) (η5-CYCLOPENTADIENYL)IRON(II) HEXAFLUOROPHOSPHATE." In Organometallic Syntheses. Elsevier, 1986. http://dx.doi.org/10.1016/b978-0-444-42607-9.50027-9.

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Ji Ram, Vishnu, Ramendra Pratap, and Pratik Yadav. "Synthesis and chemical reactivity of xanthones." In Fused Pyranones. Elsevier, 2024. http://dx.doi.org/10.1016/b978-0-12-821217-2.00007-9.

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Li, Jie Jack, Chris Limberakis, and Derek A. Pflum. "Reductions." In Modern Organic Synthesis in the Laboratory. Oxford University Press, 2008. http://dx.doi.org/10.1093/oso/9780195187984.003.0010.

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The Barton deoxygenation (or Barton–McCombie deoxygenation) is a two-step reaction sequence for the reduction of an alcohol to an alkane. The alcohol is first converted to a methyl xanthate or thioimidazoyl carbamate. Then, the xanthate or thioimidazoyl carbamate is reduced with a tin hydride reagent under radical conditions to afford the alkane. Trialkylsilanes have also been used as the hydride source. Reviews: (a) McCombie, S. W. In Comprehensive Organic Synthesis; Trost, B. M.; Fleming, I., Eds.; Pergamon Press: Oxford, U. K., 1991; Vol. 8, Chapter 4.2: Reduction of Saturated Alcohols and
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Conference papers on the topic "Synthesis of xanthone"

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Daineko, A. V., A. B. Bulatovski, and A. I. Zinchenko. "STUDY ON POTENTIAL ENGINEERING OF ESCHERICHIA COLI XANTHOSE PHOSPHORYLASE STRAIN-PRODUCER." In SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY. International Sakharov Environmental Institute of Belarusian State University, 2021. http://dx.doi.org/10.46646/sakh-2021-2-38-41.

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Genetic engineering is an actively developing branch of modern biotechnology. Using the methods of genetic engineering, it is possible to construct new forms of microorganisms that can synthesize a variety of substances, including enzymes. Xanthosine phosphorylase is the second purine nucleoside phosphorylase (PNP-II) in E. coli. This enzyme performs both reactions of phosphorolysis and the synthesis of purine deoxy / ribonucleosides. Due to this ability, xanthosine phosphorylase can catalyze the reaction of the formation of nicotinamide riboside. This substance is a precursor of the most impo
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Maia, Miguel, Andreia Palmeira, Diana Resende, Luis Gales, Madalena Pinto, and Emília Sousa. "Design and synthesis of novel xanthene derivatives." In 6th International Electronic Conference on Medicinal Chemistry. MDPI, 2020. http://dx.doi.org/10.3390/ecmc2020-07504.

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Dotsenko, Victor, Tatyana Evmeshenko, Vladimir Strelkov, and Fedor Chausov. "Some new reactions and properties of xanthane hydride." In The 21st International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2017. http://dx.doi.org/10.3390/ecsoc-21-04801.

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Matos, Maria João, Fernanda Borges, Lourdes Santana, et al. "Interest of 3-arylcoumarins as xanthine oxidase inhibitors." In The 19th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2015. http://dx.doi.org/10.3390/ecsoc-19-b002.

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Díaz Álvarez, Jesús, Carlos Marcos, and Ana Bornadiego. "Regioselective synthesis of Dihydroxanthones and Xanthones through a Tandem process." In The 20th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2016. http://dx.doi.org/10.3390/ecsoc-20-b021.

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Bouzina, Abdeslem, Rachida Mansouri, Yousra Ouafa Bouone, and Nour-Eddine Aouf. "In Silico Investigation of Two Benzoxanthone-Flavonoids: ADMET Analysis and Xanthine Oxidase Binding." In International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2024. https://doi.org/10.3390/ecsoc-28-20212.

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Gerbino, Darío, Cintia Menéndez, Fabiana Nador, Gabriel Radivoy, and Julio Podestá. "One-pot synthesis of xanthones using a novel copper-based magnetically recoverable nanocatalyst." In The 17th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2013. http://dx.doi.org/10.3390/ecsoc-17-a013.

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Sousa, Emília, Agostinho Lemos, Ana Gomes, Sara Cravo, and Madalena Pinto. "Synthesis of Aminated Xanthones: Exploiting Chemical Routes to Reach for Bioactive Compounds." In 1st International Electronic Conference on Medicinal Chemistry. MDPI, 2015. http://dx.doi.org/10.3390/ecmc-1-a022.

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Kulkarni, Pramod. "Calcium Chloride/HCl An Efficient Co-catalytic System For Synthesis Xanthene Under Microwave Condition." In The 20th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2016. http://dx.doi.org/10.3390/ecsoc-20-c001.

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Patel, Nipun, Deepak Katheriya, Harsh Dadhania, and Abhishek Dadhania. "Magnetic nanoparticle supported phosphotungstic acid: An efficient catalyst for the synthesis of xanthene derivatives." In INTERNATIONAL CONFERENCE ON NANOMATERIALS FOR ENERGY CONVERSION AND STORAGE APPLICATIONS: NECSA 2018. Author(s), 2018. http://dx.doi.org/10.1063/1.5035213.

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