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Dissertations / Theses on the topic 'Synthetic agent'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

McElroy, William Thomas. "Synthetic approaches to the anticancer agent streptonigrin." College Park, Md. : University of Maryland, 2005. http://hdl.handle.net/1903/3056.

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Thesis (Ph. D.)--University of Maryland, College Park, 2005.<br>Thesis research directed by: Chemistry. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.

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Crombie, Barry Stuart. "Synthetic approaches to the antifungal agent siccanin." Thesis, University of Salford, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.262673.

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3

Lockwood, Richard Mark. "A synthetic approach towards the antifungal agent restricticin." Thesis, University of Salford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.265398.

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4

Larek, Patryk. "Multi-Agent Traffic Assignment of a Synthetic Stockholm Population." Thesis, KTH, Transportvetenskap, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-181927.

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Static assignment methods have several limitations which form a motivation for dynamic traffic assignment (DTA). The degree project is aligned with a research project which aims to create a disaggregate model system. The components are the travel demand model Regent, the MATSim simulation framework and a commercial DTA package. The scope of the degree project is the interaction between Regent and MATSim. A synthetic population is generated by Regent. The goal of the degree project is to transform this population onto a form that can be simulated by MATSim and set up a simulation of the greater

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5

Mansfield, Darren James. "Synthetic approaches towards Squalestatin 1 : a potent anti-hypercholesterolemic agent." Thesis, University of Exeter, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.393292.

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6

Young, Amneh. "Synthetic Developments for the Treatment of Organophosphorus Nerve Agent Poisoning." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1460971499.

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7

Edwards, Cristie LeAnne. "Effect of Synthetic Chelating Agent Application to Soils on Phosphorus Availability." Thesis, Virginia Tech, 2013. http://hdl.handle.net/10919/23690.

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Fertilizer phosphorus (P) can become unavailable to crops due to immobilization of P in acidic soils through forming chemical bonds with iron (Fe) and aluminum (Al) amorphous oxides. Organic chelating agents form strong bonds with metals in soil and may reduce P binding with Fe and Al. Ethylenediamine tetraacetic acid (EDTA), hydroxyethyl ethylenediamine triacetic acid (HEEDTA), gluconic acid (GA), and citric acid (CA) were tested to determine their influence on water-soluble P (WSP), Mehlich-1 P and Mehlich-3 P in Loam and Sand soils fertilized with P and incubated for 49 days. Soil P sorp

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8

Dissanayake, Ramani. "Synthetic studies toward asymmetric C-18 analog of antitumor agent, 20(S)- camptothecin." Thesis, Kansas State University, 1997. http://hdl.handle.net/2097/13201.

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9

Jamshidi, Mohammad. "Formaldehyde as a Catalyst: Investigations on the Role of Formaldehyde as a Potential Prebiotic Catalyst and Desymmetrization Agent." Thesis, Université d'Ottawa / University of Ottawa, 2017. http://hdl.handle.net/10393/36609.

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Life, as we know it, has emerged from the association of simple building blocks (e.g. HCN, NH3, aldehydes, etc). The reactions required to form the complex subunits of life face a great entropic barrier due to the intermolecular nature of their reactivity. Intermolecular reactions are slow at low concentrations, and therefore, the assembly of complex subunits requires the presence of a concentration mechanism. Formaldehyde, which was present in concentrations as high as 0.02 M, may have been used as a concentration mechanism on early Earth. By tethering two molecules together, formaldehyde

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10

Widmark, Jörgen. "Social Agent: Facial Expression Driver for an e-Nose." Thesis, Linköping University, Department of Science and Technology, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1863.

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<p>This thesis describes that it is possible to drive synthetic emotions of an interface agent with an electronic nose system developed at AASS. The e-Nose can be used for quality control, and the detected distortion from a known smell sensation prototype is interpreted to a 3D-representation of emotional states, which in turn points to a set of pre-defined muscle contractions. This extension of a rule based motivation system, which we call Facial Expression Driver, is incorporated to a model for sensor fusion with active perception, to provide a general design for a more complex system with a

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11

Correia, J. Steve. "Agent-based target detection in 3-dimensional environments." Thesis, Monterey, California. Naval Postgraduate School, 2005. http://hdl.handle.net/10945/2300.

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Approved for public release, distribution is unlimited<br>Visual perception modeling is generally weak for game AI and computer generated forces (CGF), or agents, in computer games and military simulations. Several tricks and shortcuts are used in perceptual modeling. The results are, under certain conditions, unrealistic behaviors that negatively effect user immersion in games and call into question the validity of calculations in fine resolution military simulations. By determining what the computer-generated agent sees using methods similar to that used to generate the human players' screen

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12

Wang, Xiaoyang. "Design, Construction and Investigation of Synthetic Devices for Biological Systems." University of Cincinnati / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1314041031.

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13

Croker, Stephen John. "Synthetic studies towards a novel DNA targeted cross-linking agent based on DC-81 and CC-1065." Thesis, University of Portsmouth, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.310416.

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14

Alassadi, Abdulrahman. "An Individual-based Simulation Approach for Generating a Synthetic Stroke Population." Thesis, Malmö universitet, Malmö högskola, Institutionen för datavetenskap och medieteknik (DVMT), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-41895.

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The time to treatment plays a major factor in recovery for stroke patients, and simulation techniques can be valuable tools for testing healthcare policies and improving the situation for stroke patients. However, simulation requires individual-level data about stroke patients which cannot be acquired due to patient’s privacy rules. This thesis presents a hybrid simulation model for generating a synthetic population of stroke patients by combining Agent-based and microsimulation modeling. Subsequently, Agent-based simulation is used to estimate the locations where strokes happen. The simulatio

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15

Vignoni, Alejandro. "Invariance and Sliding Modes. Application to coordination of multi-agent systems, bioprocesses estimation, and control in living cells." Doctoral thesis, Editorial Universitat Politècnica de València, 2014. http://hdl.handle.net/10251/37743.

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The present thesis employs ideas of set invariance and sliding modes in order to deal with different relevant problems control of nonlinear systems. Initially, it reviews the techniques of set invariance as well as the more relevant results about sliding modes control. Then the main methodologies used are presented: sliding mode reference conditioning, second order sliding modes and continuous approximation of sliding modes. Finally, the methodologies are applied to different problems in control theory and to a variety of biologically inspired applications. The contributions of the the

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Wabuyele, Simuli Lindah. "DEVELOPMENT OF LC-MS/MS METHODS FOR QUANTITATIVE ANALYSIS OF PLANT-DERIVED ANTICANCER AGENT AND SYNTHETIC ESTROGEN IN COMPLEX MATRICES." Cleveland State University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=csu1400262843.

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17

Irofti, Dina. "Delay effects : a Journey from Multi-agent Systems to Genetic Networks." Thesis, Université Paris-Saclay (ComUE), 2017. http://www.theses.fr/2017SACLS136/document.

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Les sujets discutés dans cette thèses’inscrivent dans le cadre général des systèmesinterconnectés. Nous abordons les réseauxmulti-agent qui ont des tâches coopératives etnous proposons un nouveau protocole deconsensus qui comporte des retards et desagents anticipatifs. Nous étudions lesconditions pour lesquelles un réseau organiséconformément au protocole proposé atteint leconsensus. Nous dérivons également desrésultats théoriques valables pour une classeplus générale de systèmes. Ces résultatsconcernent le cas des racines multiples surl’axe des imaginaires, situation qui peutcorrespondre aux

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18

Guerrero, Razuri Javier Francisco. "Decisional-Emotional Support System for a Synthetic Agent : Influence of Emotions in Decision-Making Toward the Participation of Automata in Society." Doctoral thesis, Stockholms universitet, Institutionen för data- och systemvetenskap, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-122084.

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Emotion influences our actions, and this means that emotion has subjective decision value. Emotions, properly interpreted and understood, of those affected by decisions provide feedback to actions and, as such, serve as a basis for decisions. Accordingly, "affective computing" represents a wide range of technological opportunities toward the implementation of emotions to improve human-computer interaction, which also includes insights across a range of contexts of computational sciences into how we can design computer systems to communicate and recognize the emotional states provided by humans

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19

Li, Jian-xing. "Coupling agent effects on the interfacial adhesion in a sheath/core type bicomponent fiber." Ohio : Ohio University, 1989. http://www.ohiolink.edu/etd/view.cgi?ohiou1182441608.

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20

Chen, Weixuan. "Development of Antimicrobial Agent with Novel Mechanisms of Actions and 1,2,4,5-Tetrazine Click Chemistry and its Application in DNA Postsynthetic Functionalization." Digital Archive @ GSU, 2012. http://digitalarchive.gsu.edu/chemistry_diss/72.

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SecA ATPase is a critical member of the Sec system, which is important in the translocation of membrane and secreted polypeptides/proteins in bacteria. Small molecule inhibitors can be very useful research tools as well as leads for future antimicrobial agent development. Based on previous virtual screening work, we optimized the structures of two hit compounds and obtained SecA ATPase inhibitors with IC50 in the single digit micromolar range. These represent the first low micromolar inhibitors of bacterial SecA and will be very useful for mechanistic studies. Post synthetic modification is an

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21

Elmir, Ahmad. "PaySim Financial Simulator : PaySim Financial Simulator." Thesis, Blekinge Tekniska Högskola, Institutionen för datalogi och datorsystemteknik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-14061.

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The lack of legitimate datasets on mobile money transactions toperform research on in the domain of fraud detection is a big prob-lem today in the scientic community. Part of the problem is theintrinsic private nature of mobile transactions, not much infor-mation can be exploited. This will leave the researchers with theburden of rst harnessing the dataset before performing the actualresearch on it. The dataset corresponds to the set of data in whichthe research is to be performed on. This thesis discusses a solutionto such a problem, namely the Paysim simulator. Paysim is a -nancial simulator

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22

Bai, Hong. "Synthetic and metabolic studies on 1-methyl-4-(1-methylpyrrol-2-yl)-1,2,3,6-tetrahydropyridine, a neurotoxic analog of the Parkinsonian inducing agent MPTP." Thesis, This resource online, 1991. http://scholar.lib.vt.edu/theses/available/etd-08042009-040225/.

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23

Yu, Yue. "Conception et Développement d’une Plateforme Multi-Agent en Réalité Virtuelle de Pilotage de Véhicules Intelligents." Thesis, Ecole centrale de Lille, 2013. http://www.theses.fr/2013ECLI0013/document.

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Cette thèse est consacrée à la conception et au développement d’une plateforme multi-agent, en réalité virtuelle, de pilotage de véhicules intelligents pour la simulation du comportement microscopique du trafic. D’abord, un système de simulation intelligent des véhicules en réalité virtuelle (VR-ISSV), basé sur les multi-agents, est proposé : c’est un système modulaire hiérarchique de modélisation et de simulation, comprenant une couche matérielle, réseau et système d’exploitation ; une couche de gestion de la visualisation ; une couche de multi-agents et une couche d’interface homme-machine.

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24

Beck, Susan Ashley. "Copolymerizing Acrylonitrile and Methyl Acrylate by RAFT for Melt Processing Applications: A Synthetic Investigation of the Effects of Chain Transfer Agent, Initiator, Temperature, and Solvent." Thesis, Virginia Tech, 2014. http://hdl.handle.net/10919/49104.

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Statistical copolymers of acrylonitrile (AN) and methyl acrylate (MA) were successfully prepared and characterized using reversible addition-fragmentation chain transfer (RAFT) copolymerization. A typical copolymer was charged with 15 wt. % MA content. This thesis describes a systematic variation of the RAFT copolymerization variables to optimize this system. In particular, the effects of chain transfer agent, initiator, temperature, and solvent on the copolymer properties were studied.<br>Master of Science

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25

Abdeldayem, Ali I. A. "The effect of synthetic cannabinoids on wound healing of chondrocytes monolayers and pseudo 3D cartilage tissue. Effect of different concentrations of synthetic cannabinoids WIN55, 212-2, URB602 and HU-308 with and without their antagonists on wound healing of chondrocyte monolayers and pseudo 3D cartilage tissue." Thesis, University of Bradford, 2013. http://hdl.handle.net/10454/6316.

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Studies have been conducted to highlight the anti-inflammatory and immunosuppressive properties of cannabinoids and also their potentials for cartilage repair and regeneration. Various wound healing techniques can be used to investigate the mechanisms of chondrocyte repair in monolayers or three dimensional tissue constructs. The effect of different concentrations of the synthetic cannabinoids WIN55, 212-2 (WIN-2), URB602 and HU-308 with and without their antagonists on the wound healing of chondrocyte monolayers was investigated using a simple scratch assay model. The three cannabinoid

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Abdeldayem, Ali Ibrahim Al. "The effect of synthetic cannabinoids on wound healing of chondrocyte monolayers and pseudo 3D cartilage tissue : effect of different concentrations of synthetic cannabinoids WIN55, 212-2, URB602 and HU-308 with and without their antagonists on wound healing of chondrocyte monolayers and pseudo 3D cartilage tissue." Thesis, University of Bradford, 2013. http://hdl.handle.net/10454/6316.

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Studies have been conducted to highlight the anti-inflammatory and immunosuppressive properties of cannabinoids and also their potentials for cartilage repair and regeneration. Various wound healing techniques can be used to investigate the mechanisms of chondrocyte repair in monolayers or three dimensional tissue constructs. The effect of different concentrations of the synthetic cannabinoids WIN55, 212-2 (WIN-2), URB602 and HU-308 with and without their antagonists on the wound healing of chondrocyte monolayers was investigated using a simple scratch assay model. The three cannabinoids were

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27

Vosooghi, Reza. "Shared autonomous vehicle service design, modeling, and simulation." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLC071.

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Les Robot-Taxis constituent la prochaine évolution majeure de la mobilité urbaine. Cette technologie intéresse certains constructeurs automobiles qui envisagent de jouer le rôle des entreprises de transport. Ceci leur permet de développer un modèle d'affaire basé sur des revenues par kilomètre et par trajet. Un service basé sur des véhicules autonomes a l’avantage de pouvoir fusionner des systèmes de service de taxis classiques à la demande et de voitures en libre-service. Ainsi ce service de transport unifié offre une forme de mobilité partagée plus accessible, dynamique et intelligente. Le s

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28

Lopez-Rojas, Edgar Alonso. "Applying Simulation to the Problem of Detecting Financial Fraud." Doctoral thesis, Blekinge Tekniska Högskola, Institutionen för datalogi och datorsystemteknik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-12932.

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This thesis introduces a financial simulation model covering two related financial domains: Mobile Payments and Retail Stores systems. The problem we address in these domains is different types of fraud. We limit ourselves to isolated cases of relatively straightforward fraud. However, in this thesis the ultimate aim is to introduce our approach towards the use of computer simulation for fraud detection and its applications in financial domains. Fraud is an important problem that impact the whole economy. Currently, there is a lack of public research into the detection of fraud. One importan

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Kandanapitiye, Murthi S. "Synthesis of Biocompatible Nanoparticulate Coordination Polymers for Diagnostic and Therapeutic Applications." Kent State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=kent1429019837.

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30

Phillips, Glenn Walton. "Synthetic studies toward the total synthesis of fostriecin and some analogs." Diss., Connect to online resource - MSU authorized users, 2006.

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31

Sheth, Ritesh B. "Development of new synthetic methodologies and the synthesis of natural products." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 101 p, 2010. http://proquest.umi.com/pqdweb?did=1993336351&sid=2&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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32

Thorpe, Andrew John. "Synthetic approaches to novel adenosine analogues and the synthesis of potential antiviral agents." Thesis, University of Exeter, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.357951.

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33

Narquizian, Robert. "Synthetic studies on the pederin family of antitumour agents : synthesis of pederin, mycalamide B and analogues." Thesis, University of Glasgow, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.274781.

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NGUYEN, THI-VUONG. "Recherche d'inhibiteurs de lipoxygenases." Paris 6, 1988. http://www.theses.fr/1988PA066441.

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Conception de nouveaux composes susceptibles d'inhiber les lipoxygenases et synthese. Les inhibiteurs potentiels ont ete testes sur les leucocytes humains et les graines de soja. L'un d'eux, ah, a ete brevete comme medicament antiinflammatoire

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35

Hendrix, Martin. "Synthetic approaches toward pancratistatin." Thesis, Georgia Institute of Technology, 1993. http://hdl.handle.net/1853/27300.

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Perrier, SeÌbastien. "Synthesis of novel surface active agents via copper mediated living radical polymerisation : synthetic and mechanistic study." Thesis, University of Warwick, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.246763.

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37

Lin, Tung Yin. "Synthetic studies towards the stellettins /." View online, 2008. http://repository.eiu.edu/theses/docs/32211131443971.pdf.

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38

Roe, Michael B. "Synthetic studies towards solenolides." Thesis, University of Salford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.238837.

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Madin, Andrew. "Synthesis of antiparasitic agents." Thesis, Imperial College London, 1990. http://hdl.handle.net/10044/1/46422.

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White, Anthony R. P. "SynthECA, a synthetic ecology of chemical agents." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0017/NQ57632.pdf.

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Critchley, Trevor. "Synthetic studies towards naturally occuring antihypercholesterolaemic agents." Thesis, University of Nottingham, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.299552.

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Gorsuch, Stephen. "Synthetic approaches towards novel anti-HIV agents." Thesis, University of Reading, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.265108.

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White, Anthony R. P. (Anthony Richard Phillip) Carleton University Dissertation Engineering Systems and Computer. "SynthECA: a synthetic ecology of chemical agents." Ottawa, 2000.

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44

Sha, Li. "A synthetic approach to FR901483." Morgantown, W. Va. : [West Virginia University Libraries], 2001. http://etd.wvu.edu/templates/showETD.cfm?recnum=2103.

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Thesis (M.S.)--West Virginia University, 2001.<br>Title from document title page. Document formatted into pages; contains vii, 57 p. : ill. Includes abstract. Includes bibliographical references (p. 55-57).

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Yuen, Tsz Ying. "Enantioselective total synthesis of the antimitotic agent paecilospirone." Thesis, University of Auckland, 2011. http://hdl.handle.net/2292/10767.

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This thesis describes the first, enantioselective total synthesis of the marine natural product paecilospirone (1). Paecilospirone is a polyketide derived metabolite isolated from the marine fungus Paecilomyces sp. collected off the coast of Yap Island, Federated States of Micronesia. Structural assignment following anticancer bioassay subsequently revealed a novel spiro[chroman-2,1(3H)- isobenzofuran] core where an -hydroxyl group occupies the unusual axial position of the sixmembered tetrahydropyran ring. An efficient and flexible strategy was developed to provide access to the [5,6]-bisbenz

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Provencher, Philip. "Synthesis and performance of an alkylating agent sensor." Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/50918.

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4-(4-nitrobenzyl)pyridine (NBP) is a colorimetric indicator compound for many types of carcinogenic alkylating agents. It is used in the toxicological screening of pharmaceutical compounds, detection of chemical warfare agents, environmental hygiene technology, and other chemical analyses. We report a synthesis of NBP-derivatives that allow for the covalent incorporation of NBP into a solid state sensor. These derivatives have been tested in solution and found to be superior in the colorimetric assay of the alkylating agent cyclophosphamide. The derivatives have also been integrated into a pol

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Romanovski, Iakov. "Multi-agent product systems : analysis, synthesis and control." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=84427.

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This thesis presents new approach to the supervisory control of complex systems modelled as Multi-Agent (MA) products of finite deterministic automata.<br>First, the centralized supervisory control problem for the MA product is considered. This differs from the standard approach to supervisory control since (i) vector languages are under consideration and (ii) each supervisor can disable only one particular component of a vector event. The notion of MA controllability is introduced and is shown to essentially constitute a necessary and sufficient condition for the synthesis of an MA sup

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Stock, Nicholas Simon. "The total synthesis of the antifungal agent Pramanicin." Thesis, Imperial College London, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.314372.

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49

Pearse, Stephen. "Agent-based graphic sound synthesis and acousmatic composition." Thesis, University of Sheffield, 2016. http://etheses.whiterose.ac.uk/15892/.

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For almost a century composers and engineers have been attempting to create systems that allow drawings and imagery to behave as intuitive and efficient musical scores. Despite the intuitive interactions that these systems afford, they are somewhat underutilised by contemporary composers. The research presented here explores the concept of agency and artificial ecosystems as a means of creating and exploring new graphic sound synthesis algorithms. These algorithms are subsequently designed to investigate the creation of organic musical gesture and texture using granular synthesis. The output o

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Shehata, Sara <1993&gt. "Synthesis of Anti-Metastatic Agent for Cancer Theraphy." Master's Degree Thesis, Università Ca' Foscari Venezia, 2018. http://hdl.handle.net/10579/13854.

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Breast cancer is the most common cancer in women worldwide and is the cause of millions of deaths around the world each year. The majority of breast cancer related mortalities are a result of metastatic disease involving the formation of secondary tumours where cancer cells have spread from the primary tumour to sites around the body. Among the most difficult to treat are those which belong to the basal-type, or triple-negative intrinsic molecular class as these lack the three key hormone receptors: oestrogen (ER), progesterone (PGR) and human epithelial receptor 2 (Her2) which are the targets

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