Academic literature on the topic 'Synthetic estrogen'

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Journal articles on the topic "Synthetic estrogen"

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Hashimoto, T., K. Takahashi, and T. Murakami. "Characteristics of estrogen decomposition by ozonation." Water Science and Technology 54, no. 10 (2006): 87–93. http://dx.doi.org/10.2166/wst.2006.806.

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Since the natural estrogens 17 β-estradiol (E2) and estron (E1), and the synthetic estrogen 17 α-ethynyl estradiol (EE2) have strong endocrine disrupting effects and the tendency to persist in effluent from wastewater treatment plants, effective measures are needed to remove them from wastewater. In this research, to gain an understanding of the characteristics of estrogen decomposition by ozonation, experiments were conducted using effluent from an actual wastewater treatment plant. In this experiment, estrogen was added to effluent at a concentration of 200 ng/l and 20 ng/l before the ozonat
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Liang, Rubing, Jing Zhou, and Jianhua Liu. "Construction of a Bacterial Assay for Estrogen Detection Based on an Estrogen-Sensitive Intein." Applied and Environmental Microbiology 77, no. 7 (2011): 2488–95. http://dx.doi.org/10.1128/aem.02336-10.

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ABSTRACTEscherichia colistrain DIER was constructed for estrogen detection by inserting an estrogen-sensitive intein (VMAERintein) into the specific site of the constitutively expressed chromosomallacZgene. This VMAERintein was generated by replacing the endonuclease region of theSaccharomyces cerevisiaeVMA intein with the estrogen binding region of the human estrogen receptor α (hERα). When there were estrogens or analogs, the splicing of the VMAERintein was induced to produce the mature LacZ protein, which was detected through a β-galactosidase colorimetric assay. Eight typical chemicals (17
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Shi, J. H., Y. Suzuki, S. Nakai, and M. Hosomi. "Microbial degradation of estrogens using activated sludge and night soil-composting microorganisms." Water Science and Technology 50, no. 8 (2004): 153–59. http://dx.doi.org/10.2166/wst.2004.0510.

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In order to investigate the potential for microbial degradation of estrogens, and the products formed, activated sludge collected from Korea (ASK) and night soil-composting microorganisms (NSCM) were used to degrade estrogens. Results showed that both ASK and NSCM degraded almost 100% of the natural estrogens estrone (E1), 17β-estradiol (E2), and estriol (E3) from initial concentrations of 20-25 mg/L, while synthetic estrogen, ethynylestradiol (EE2), was not degraded. Analysis of degradation products of E2 by using HPLC-ECD and a consecutive first-order reaction calculation confirmed that E2 w
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Safe, Stephen H., Lea Pallaroni, Kyungsil Yoon, et al. "Toxicology of environmental estrogens." Reproduction, Fertility and Development 13, no. 4 (2001): 307. http://dx.doi.org/10.1071/rd00108.

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It has been hypothesized that environmental contaminants that modulate endocrine signaling pathways may be causally linked to adverse health effects in humans. There has been particular concern regarding synthetic estrogens and their role in disrupting normal development of the male reproductive tract. Most estrogenic industrial compounds, such as bisphenol A (BPA) and nonylphenol, typically bind estrogen receptors α (ERα) and β (ERβ) and induce transactivation of estrogen-responsive genes/reporter genes, but their potencies are usually ≥1000-fold lower than observed for 17β-estradiol (E2). Se
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Nikov, GN, M. Eshete, RV Rajnarayanan, and WL Alworth. "Interactions of synthetic estrogens with human estrogen receptors." Journal of Endocrinology 170, no. 1 (2001): 137–45. http://dx.doi.org/10.1677/joe.0.1700137.

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Synthetic estrogens have diverse chemical structures and may either positively or negatively affect the estrogenic signaling pathways through interactions with the estrogen receptors (ERs). Modeling studies suggest that 4-(1-adamantyl)phenol (AdP) and 4,4'-(1,3-adamantanediyl)diphenol (AdDP) can bind in the ligand binding site of ERalpha. We used fluorescence polarization (FP) to compare the binding affinities of AdP, AdDP and 2-(1-adamantyl)-4-methylphenol (AdMP) for human ERalpha and ERbeta with the binding affinities of the known ER ligands, diethylstilbestrol (DES) and 4hydroxytamoxifen (4
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Hammett, Kirsten M., Gary K. Felton, Daniel J. Fisher, Lance T. Yonkos, Elizabeth J. Mullin, and Diana S. Aga. "Integrated Assessment of Aqueously Extractable Estrogens in Municipal Biosolids after Pilot-Scale Composting." Transactions of the ASABE 60, no. 5 (2017): 1645–58. http://dx.doi.org/10.13031/trans.12241.

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Abstract. Municipal biosolids contain natural estrogens, e.g., 17ß-estradiol (E2) and estrone (E1), and synthetic estrogens, e.g., 17a-ethinylestradiol (EE2), which can be transported to receiving waters via runoff when land-applied as fertilizer. Previous studies have investigated estrogens in runoff from biosolids-amended fields but have not tracked changes in estrogenicity within this water over time. Microbial conversion of conjugated estrogens (a major portion of water-extractable estrogens) to parent forms may result in temporary increases in estrogenicity in natural water bodies. The pr
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Walters, M. J., T. J. Brown, R. B. Hochberg, and N. J. MacLusky. "In vitro autoradiographic visualization of occupied estrogen receptors in the rat brain with an iodinated estrogen ligand." Journal of Histochemistry & Cytochemistry 41, no. 9 (1993): 1279–90. http://dx.doi.org/10.1177/41.9.8354873.

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Methods have been developed for the selective measurement of occupied estrogen receptors (ER) in brain tissue sections. Cryostat sections of unfixed tissue were incubated with radiolabeled estrogen at physiological temperatures, displacing endogenous receptor-bound estrogen by radioligand and thereby allowing the receptor complexes to be visualized autoradiographically after washing to remove nonspecifically bound steroid. The resultant autoradiographs were analyzed by computer-assisted densitometry. Synthetic 11 beta-methoxy-substituted radiolabeled estrogens gave the best autoradiographic im
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Peretz, Jackye, Andrew Pekosz, Andrew P. Lane, and Sabra L. Klein. "Estrogenic compounds reduce influenza A virus replication in primary human nasal epithelial cells derived from female, but not male, donors." American Journal of Physiology-Lung Cellular and Molecular Physiology 310, no. 5 (2016): L415—L425. http://dx.doi.org/10.1152/ajplung.00398.2015.

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Influenza causes an acute infection characterized by virus replication in respiratory epithelial cells. The severity of influenza and other respiratory diseases changes over the life course and during pregnancy in women, suggesting that sex steroid hormones, such as estrogens, may be involved. Using primary, differentiated human nasal epithelial cell (hNEC) cultures from adult male and female donors, we exposed cultures to the endogenous 17β-estradiol (E2) or select estrogen receptor modulators (SERMs) and then infected cultures with a seasonal influenza A virus (IAV) to determine whether estr
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Almeida, Maria, Michaël R. Laurent, Vanessa Dubois, et al. "Estrogens and Androgens in Skeletal Physiology and Pathophysiology." Physiological Reviews 97, no. 1 (2017): 135–87. http://dx.doi.org/10.1152/physrev.00033.2015.

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Estrogens and androgens influence the growth and maintenance of the mammalian skeleton and are responsible for its sexual dimorphism. Estrogen deficiency at menopause or loss of both estrogens and androgens in elderly men contribute to the development of osteoporosis, one of the most common and impactful metabolic diseases of old age. In the last 20 years, basic and clinical research advances, genetic insights from humans and rodents, and newer imaging technologies have changed considerably the landscape of our understanding of bone biology as well as the relationship between sex steroids and
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Penning, Trevor M. "Genotoxicity of ortho-quinones: reactive oxygen species versus covalent modification." Toxicol. Res. 6, no. 6 (2017): 740–54. http://dx.doi.org/10.1039/c7tx00223h.

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o-Quinones are formed metabolically from natural and synthetic estrogens as well as upon exposure to polycyclic aromatic hydrocarbons (PAH) and contribute to estrogen and PAH carcinogenesis by genotoxic mechanisms.
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Dissertations / Theses on the topic "Synthetic estrogen"

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Brummer, Tyson Peter Thomas. "Comparative Immunological Effects of a Natural Estrogen (17β-estradiol) versus a Pharmacologic Synthetic Estrogen (17α-ethinyl estradiol)". Thesis, Virginia Tech, 2007. http://hdl.handle.net/10919/34601.

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Exposure to exogenous estrogens such as synthetic 17α-ethinyl estradiol (EE) occurs via multiple sources (i.e. hormonal contraceptives, environmental contamination, hormone replacement therapy). The natural estrogen, 17β-estradiol (E2), is a well-studied immunomodulatory hormone at both environmental and pharmacologic levels. Conversely, little data exist regarding the immune effects of EE at either environmentally-relevant exposure levels or at pharmacological levels. Further, EE is delivered to patients in a clinical setting via different routes of exposure (e.g. subcutaneous or oral).
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Cops, Elisa Jane. "Mibolerone, a synthetic androgen, opposes estrogen signalling in breast cancer cells /." Cover title, title page and abstract only, 2003. http://web4.library.adelaide.edu.au/theses/09SB/09sbc7857.pdf.

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Bhat, Abhijit Suresh. "A. Synthesis and biochemical evaluation of estrogen analogs. ; B. Synthetic strategies for constructing benzopyrone combinatorial libraries /." The Ohio State University, 1999. http://rave.ohiolink.edu/etdc/view?acc_num=osu1488190595941695.

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Geminiani, Lorenzo. "Synthetic studies towards a new fulvestrant analogue." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2016. http://amslaurea.unibo.it/10004/.

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A study towards the synthesis of a new fulvestrant analogue with improved bioavailability was carried out. In this work a twelve-step synthetic route starting from β-estradiol was optimized and a palladium (Pd)-catalyzed endo-selective Heck reaction for the functionalization of an advanced intermediate was investigated.
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Brown, Nicole Chantae. "The mechanism of T cell dysfunction induced by Diethylstilbestrol." VCU Scholars Compass, 2005. http://scholarscompass.vcu.edu/etd/1321.

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Estrogens have the ability to alter the immune system. Diethylstilbestrol (DES), asynthetic estrogen, is known to have estrogenic activity and induce thymic alterations.We investigated the mechanism by which DES is able to alter T cells and thus theimmune system. First, we studied the effect of DES on mature T cells by using the T cellleukemia cell line, Jurkat. We found that DES treatment reduced cell viability andincreased apoptosis. Additionally, apoptosis was found to involve both death receptorand mitochondria1 pathways. Furthermore, estrogen receptor beta was found to beexpressed in thes
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Wabuyele, Simuli Lindah. "DEVELOPMENT OF LC-MS/MS METHODS FOR QUANTITATIVE ANALYSIS OF PLANT-DERIVED ANTICANCER AGENT AND SYNTHETIC ESTROGEN IN COMPLEX MATRICES." Cleveland State University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=csu1400262843.

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Riman, Tomas. "An epidemiologic study of epithelial ovarian malignancies : with a focus on hormone-related factors /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-362-7/.

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Miguel, Mariana. "Efeito do hormônio sintético 17α-etinilestradiol no invertebrado aquático Daphnia magna (Crustacea, Cladocera)." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/18/18139/tde-31032016-101847/.

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Muitas substâncias descartadas no meio ambiente não são totalmente degradadas, podendo assim persistir no ambiente. Diversos compostos são continuamente introduzidos no ambiente podendo afetar a biota e inclusive o homem. Os fármacos são alguns desses compostos que depois de descartados podem chegar nos corpos de águas naturais, e dentre eles merecem especial atenção os hormônios sintéticos utilizados em larga escala por mulheres em todo o mundo, na forma de contraceptivos orais. O hormônio sintético 17α-etinilestradiol é um micropoluente no ambiente aquático, que pode causar distúrbios n
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Karolczak, Magdalena. "Estrogen synthesis and novel mechanisms of estrogen action in the developing brain." Ulm : Universität Ulm, Medizinische Fakultät, 2000. http://www.bsz-bw.de/cgi-bin/xvms.cgi?SWB9394023.

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Karolczak, Magdalena [Verfasser]. "Estrogen synthesis and novel mechanisms of estrogen action in the developing brain / Magdalena Karolczak." Ulm : Universität Ulm. Medizinische Fakultät, 2001. http://d-nb.info/1015473156/34.

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Books on the topic "Synthetic estrogen"

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Angerer, Erwin von. The estrogen receptor as a target for rational drug design. Springer, 1995.

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Angerer, Erwin von. The estrogen receptor as a target for rational drug design. Springer, 1995.

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Elke, Dopp, Stopper Helga, Alink Gerrit Mannes, and Research Signpost (Trivandrum India), eds. Natural and synthetic estrogens: Aspects of the cellular and molecular activity. Research Signpost, 2002.

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Parker, Philip M. The 2007-2012 World Outlook for Estrogen Hormones and Synthetic Substitute Pharmaceuticals. ICON Group International, Inc., 2006.

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The 2006-2011 World Outlook for Estrogen Hormones and Synthetic Substitute Pharmaceuticals. Icon Group International, Inc., 2005.

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Parker, Philip M. The 2007-2012 Outlook for Estrogen Hormones and Synthetic Substitute Pharmaceuticals in Japan. ICON Group International, Inc., 2006.

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Parker, Philip M. The 2007-2012 Outlook for Estrogen Hormones and Synthetic Substitute Pharmaceuticals in India. ICON Group International, Inc., 2006.

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Parker, Philip M. The 2007-2012 Outlook for Estrogen Hormones and Synthetic Substitute Pharmaceuticals in Greater China. ICON Group International, Inc., 2006.

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Castellanos, Madeleine M. Female Sexual Biochemistry (DRAFT). Edited by Madeleine M. Castellanos. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190225889.003.0001.

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“Female Sexual Biochemistry” reviews the key hormones and neurotransmitters that have a major role in female sexuality. Estrogens—estradiol, estrone, and estriol—as well as major androgens, such as testosterone and dihydrotestosterone (DHT), are presented with a discussion of their role in the support of the reproductive organs and genitals as well as their actions on the central nervous system to affect sexual desire, arousal, and responsiveness. The interaction and regulation of estrogen by progesterone and thyroid hormone is included. A review of the dual-control model of sexual responsiven
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Parker, Philip M. The 2007-2012 Outlook for Estrogen Hormones and Synthetic Substitute Pharmaceuticals in the United States. ICON Group International, Inc., 2006.

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Book chapters on the topic "Synthetic estrogen"

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Hendry, William J., Xinglong Zheng, Wendell W. Leavitt, William S. Branham, and Daniel M. Sheehan. "Synthetic Estrogen-Mediated Alterations in Uterine Cell Fate." In Cell Death in Reproductive Physiology. Springer New York, 1997. http://dx.doi.org/10.1007/978-1-4612-1944-6_20.

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Piñeiro-Núñez, Marta. "Raloxifene, Evista: A Selective Estrogen Receptor Modulator (SERM)." In Modern Drug Synthesis. John Wiley & Sons, Inc., 2010. http://dx.doi.org/10.1002/9780470768594.ch20.

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Sobek, L., and V. K. Patchev. "Phylogeny of Estrogen Synthesis, Extragenital Distribution of Estrogen Receptors and Their Developmental Role." In Estrogens and Antiestrogens I. Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/978-3-642-58616-3_13.

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Hillisch, A., O. Peters, D. Kosemund, et al. "Protein Structure-Based Design, Synthesis Strategy and In Vitro Pharmacological Characterization of Estrogen Receptor α and β Selective Compounds." In New Molecular Mechanisms of Estrogen Action and Their Impact on Future Perspectives in Estrogen Therapy. Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-662-05386-7_4.

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Kuhnz, W., H. Blode, and H. Zimmermann. "Pharmacokinetics of Exogenous Natural and Synthetic Estrogens and Antiestrogens." In Handbook of Experimental Pharmacology. Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-60107-1_15.

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Cowie, A. T. "Artificial Induction of Lactation in Goats by Steroid Hormones and Synthetic Estrogens." In Ciba Foundation Symposium - Steroid Hormone Administration (Book II of Colloquia on Endocrinology, Vol. 3). John Wiley & Sons, Ltd, 2008. http://dx.doi.org/10.1002/9780470715154.ch9.

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Li, Jonathan J., Hadley Kirkman, and Sara Antonia Li. "Synthetic Estrogens and Liver Cancer: Risk Analysis of Animal and Human Data." In Hormonal Carcinogenesis. Springer New York, 1992. http://dx.doi.org/10.1007/978-1-4613-9208-8_28.

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Ganguly, Karabi, and Swati Sikdar. "Insulin Attenuated Estrogen Receptor in Neutrophil Dwindled Synthesis of Maspin in Breast Cancer." In Lecture Notes in Bioengineering. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-33-6915-3_16.

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Broom, W. A. "Observations on the Results of Pharmacological Assay of Synthetic Estrogens and Their Clinical Effects." In Ciba Foundation Symposium - Steroid Hormone Administration (Book II of Colloquia on Endocrinology, Vol. 3). John Wiley & Sons, Ltd, 2008. http://dx.doi.org/10.1002/9780470715154.ch11.

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Katzenellenbogen, Benita S., Yhun Yhong Sheen, Catherine E. Snider, and Yolande Berthois. "Estrogen and Antiestrogen Regulation of Proliferation and Protein Synthesis of Human Breast Cancer Cells." In Steroid Receptors in Health and Disease. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5541-0_15.

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Conference papers on the topic "Synthetic estrogen"

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Haroutounian, Serkos, and Sofia Koulocheri. "Ultrasound Promoted Synthesis of 2,3-bis-(4-Hydroxyphenyl)-indoles as Inherently Fluorescent Ligands for the Estrogen." In The 4th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2000. http://dx.doi.org/10.3390/ecsoc-4-01911.

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Crowder, R., C. Phommaly, C. Sanchez, C. Sanchez, M. Ellis, and M. Ellis. "Phosphoinositide-3-Kinase Catalytic Subunit Inhibition Does Not Produce Synthetic Lethality in Estrogen Receptor Positive Breast Cancer Cells with Acquired Resistance to Estrogen Deprivation." In Abstracts: Thirty-Second Annual CTRC‐AACR San Antonio Breast Cancer Symposium‐‐ Dec 10‐13, 2009; San Antonio, TX. American Association for Cancer Research, 2009. http://dx.doi.org/10.1158/0008-5472.sabcs-09-3131.

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Daurio, Natalie A., Stephen Tuttle, and Constantinos Koumenis. "Abstract 5510: Tamoxifen induces estrogen receptor-independent bioenergetic stress: A synthetic lethality approach to target tumor metabolism." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-5510.

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Salleh, Mohd Nazil, Tan Mei Cheng, Thuaibah Hashim, Henkie Isahwan Ahamd Mulyadi Lai, and Wan Khairuzzaman Wan Ramli. "Abstract A51: p53 and p21 mRNA and protein expression in treated synthetic estrogen in mouse transgenic animal model." In Abstracts: Third AACR International Conference on Frontiers in Basic Cancer Research - September 18-22, 2013; National Harbor, MD. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.fbcr13-a51.

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Crowder, RJ, C. Phommaly, J. Hoog, et al. "Synthetic lethality when combining phosphoinositide 3-kinase alpha and beta catalytic subunit-directed RNAi and estrogen deprivation for estrogen receptor positive breast cancer: implications for clinical trial design with pharmacological inhibitors." In CTRC-AACR San Antonio Breast Cancer Symposium: 2008 Abstracts. American Association for Cancer Research, 2009. http://dx.doi.org/10.1158/0008-5472.sabcs-3063.

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Tran, Kim M., Renee Risingsong, Darlene Royce, Charlotte R. Williams, Michael B. Sporn, and Karen Liby. "Abstract A103: The synthetic triterpenoid CDDO-methyl ester targets tumor-associated macrophages to delay carcinogenesis in the PyMT model of estrogen receptor negative breast cancer." In Abstracts: AACR International Conference on Frontiers in Cancer Prevention Research‐‐ Oct 22-25, 2011; Boston, MA. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1940-6207.prev-11-a103.

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Thornton, Gail M., Soraya J. Bailey, Xinxin Shao, Douglas Morck, David A. Hart, and Yamini Achari. "Influence of Early Ovariohysterectomy on the Mechanical Properties of Rabbit Medial Collateral Ligament." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176260.

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Female athletes have significantly higher incidence of anterior cruciate ligament (ACL) injuries than males participating in similar sports [1]. To date, no clear explanation has emerged for this disparity. However, hormonal differences may provide an explanation because some ACL injuries have been linked to physiologic fluctuations in estrogen levels over the menstrual cycle [2]. Receptors for estrogen have been identified in rabbit and human ACLs and medial collateral ligaments (MCLs) [3]. Increased estrogen levels caused decreased fibroblast proliferation and collagen synthesis in cell cult
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Ataei, Abdol Hossain, and Figen Kırkpınar. "Application of In-Ovo Injection of Some Substances for Manipulation of Sex and Improving Performance in Chicken." In International Students Science Congress. Izmir International Guest Student Association, 2021. http://dx.doi.org/10.52460/issc.2021.006.

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In intensive production, freshly hatched cockerels are culled in the layer hatchery (7 billion males each year), On the other hand, for meat production rearing female birds has not economic benefits because of male broiler chicks have a faster growth rate and better feed efficiency than females. In this regards several methods are being developed for sex determination in the chick embryo during the incubation period. But these methods need to be rapid, cost-efficient, and suitable practical for commercial use. Additionally, sex determination should be done before pain perception has evolved in
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Tran, Kim M., Michael B. Sporn, and Karen Liby. "Abstract 820: The synthetic triterpenoids, CDDO-methyl ester and CDDO-ethyl amide, and the histone deacetylase inhibitor vorinostat delay carcinogenesis in a transgenic model of estrogen receptor-negative breast cancer." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-820.

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Terent'ev, S. S., V. I. Velikanov, A. V. Kljapnev, et al. "FEATURES COLOSTRAL IMMUNITY CALVES IN COMBINED STIMULATION PREGNANT COWS IMMUNOMODULATORS AND SYNESTROL2%." In "International Scientific and Practical Conference" THEORY AND PRACTICE OF VETERINARY PHARMACY, ECOLOGY AND TOXICOLOGY IN AIC ", dedicated to the centenary of the Department of Pharmacology and Toxicology, SPbSUVM. FSBEI HE St. Petersburg SUVM, 2021. http://dx.doi.org/10.52419/3006-2021-2-225-228.

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The purpose of our experiment was to study the effect of the combined administration of an immunomodulator and a synthetic analogue of estrone to cows 3-5 days before calving on the colostral immunity of calves. The result of the work showed that the calves obtained from such cows have a greater number of leukocytes, T-lymphocytes and B-lymphocytes at birth. A synthetic analogue of estrone probably cross the placenta and affect the fetus, which is reflected in the acceleration of the metabolism of the newborn. As a result, there was an accelerated assimilation of colostrum from the gastrointes
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Reports on the topic "Synthetic estrogen"

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Hussey, Stephen L., and Blake Peterson. Novel Synthetic Antiestrogens That Block Nuclear Estrogen Receptor Function Through Plasma Membrane Localization. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada415782.

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Tongcharoensirikul, Pakamas. Synthesis of Estrogen Receptor Beta Selective 17-Substituted Estradiols for the Treatment of Prostate Cancer. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada427891.

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Hanson, Robert. A Structure Based, Solid Phase Synthesis Approach to the Development of Novel Selective Estrogen Receptor Modulatory Steroids. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada383168.

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Hanson, Robert N. A Structure Based, Solid-Phase Synthesis Approach to the Development of Novel Selective Estrogen Receptor Modulatory Steroids. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada407782.

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Hanson, Robert N. A Structure Based, Solid Phase Synthesis Approach to the Development of Novel Selective Estrogen Receptor Modulatory Steroids. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada403350.

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