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Journal articles on the topic 'Synthetic vascular grafts'

Author: Grafiati

Published: 10 December 2022

Last updated: 28 January 2023

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1

Aleksandrov, Viktor Nikolayevich, Genady Grigorievich Khubulava, and Vladimir Victorovich Levanovich. "Tissue-engineered vascular grafts." Pediatrician (St. Petersburg) 6, no. 1 (2015): 87–95. http://dx.doi.org/10.17816/ped6187-95.

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There is no doubt that the introduction of synthetic materials was the prerequisite for success of vascular surgery. Biological inertness, durability, eases of sterilization and modeling of synthetic vascular grafts contributed to their widespread use as in aortic and great vessels. However, analysis of the accumulated clinical experience in using of synthetic grafts showed that fascination with them was gradually replaced by cautious attitude, and sometimes by refusing, because in the presence of well-known advantages, synthetic grafts are prone to thrombosis and the development of infection.

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2

Kanda, Keiichi, Hiromichi Miwa, and Takehisa Matsuda. "Phenotypic Reversion of Smooth Muscle Cells in Hybrid Vascular Prostheses." Cell Transplantation 4, no. 6 (1995): 587–95. http://dx.doi.org/10.1177/096368979500400608.

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Our purpose was to evaluate whether or not and when phenotypic modulation of smooth muscle cells (SMCs) in hybrid vascular prostheses preincorporated with SMCs occurs upon implantation. Two types of hybrid vascular grafts incorporated with vascular cells derived from canine jugular veins were prepared: grafts containing a collagen gel layer covered with an endothelial monolayer at the luminal surface (Model I graft) and those containing an endothelial monolayer and SMC multilayer (Model II graft). They were bilaterally implanted into carotid arteries of the same dogs from which the cells had b

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3

Antonova, L. V., E. O. Krivkina, M. Yu Khanova, et al. "Results of preclinical trials in a sheep model of biodegradable small-diameter vascular grafts." Russian Journal of Transplantology and Artificial Organs 24, no. 3 (2022): 80–93. http://dx.doi.org/10.15825/1995-1191-2022-3-80-93.

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Surface modification of polymer vascular matrices is a promising development for preventing vascular graft thrombosis, improving long-term patency and accelerating remodeling. Objective: to study the outcomes of long-term patency of PHBV/PCL/GFmix grafts with iloprost (Ilo) and heparin (Hep) implanted into the carotid artery of sheep. Materials and methods. Matrices 04 mm were fabricated by electrospinning from a polymer composition of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) and poly(s-caprolactone) (PCL) with incorporation of endothelial growth factor (VEGF), basic fibroblast grow

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4

Mohr, Lester L., Douglas C. Smith, and Gregory J. Schaner. "Catheterization of synthetic vascular grafts." Journal of Vascular Surgery 3, no. 6 (1986): 854–56. http://dx.doi.org/10.1067/mva.1986.avs0030854.

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5

Mohr, Lester L., Douglas C. Smith, and Gregory J. Schaner. "Catheterization of synthetic vascular grafts." Journal of Vascular Surgery 3, no. 6 (1986): 854–56. http://dx.doi.org/10.1016/0741-5214(86)90149-7.

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6

Yuan, Xingyu, Wen Li, Bin Yao, et al. "Tri-Layered Vascular Grafts Guide Vascular Cells’ Native-like Arrangement." Polymers 14, no. 7 (2022): 1370. http://dx.doi.org/10.3390/polym14071370.

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Bionic grafts hold great promise for directing tissue regeneration. In vascular tissue engineering, although a large number of synthetic grafts have been constructed, these substitutes only partially recapitulated the tri-layered structure of native arteries. Synthetic polymers such as poly(l-lactide-co-ε-caprolactone) (PLCL) possess good biocompatibility, controllable degradation, remarkable processability, and sufficient mechanical strength. These properties of PLCL show great promise for fabricating synthetic vascular substitutes. Here, tri-layered PLCL vascular grafts (TVGs) composed of a

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7

Wang, Yadong, Wei Wu, and Robert Allen. "Vitalize synthetic vascular grafts in vivo." Cardiovascular Pathology 22, no. 3 (2013): e51. http://dx.doi.org/10.1016/j.carpath.2013.01.075.

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8

Adipurnama, Iman, Ming Chien Yang, Tomasz Ciach, and Beata Butruk Raszeja. "Surface Modification With Gelatin For Polyurethane Vascular Grafts: A Review." Jurnal Bahan Alam Terbarukan 8, no. 2 (2020): 100–117. http://dx.doi.org/10.15294/jbat.v8i2.23170.

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The means for developing synthetic vascular grafts to replace blood vessels is increasing extensively because of the limited supply of autologous vessels. Synthetic polymers as the alternatives still suffer from restenosis and thrombus formation. Natural polymers, on the other hand, are commonly biocompatible and biodegradable, compliment the synthetic ones. Blending, grafting and coating of natural polymers have been proposed to improve surface properties of synthetic polymers. Gelatin is a promising candidate to help improving synthetic vascular grafts surface owing to its ability to promote

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9

Gao, Jingchen, Yaping Wang, Siyuan Chen та ін. "Electrospun poly-ε-caprolactone scaffold modified with catalytic nitric oxide generation and heparin for small-diameter vascular graft". RSC Advances 7, № 30 (2017): 18775–84. http://dx.doi.org/10.1039/c7ra02086d.

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Vascular grafts are significantly needed in peripheral vascular surgery; however, small diameter grafts are not always available, and synthetic grafts perform poorly because of acute thrombosis and neointimal proliferation after implantation.

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10

Gerrah, Rabin, Rachel E. Sunstrom PA-C, and Alan R. Hohimer. "Pretreatment of synthetic vascular grafts with heparin before implantation, a simple technique to reduce the risk of thrombosis." Vascular 23, no. 5 (2014): 513–18. http://dx.doi.org/10.1177/1708538114560455.

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Thrombosis of synthetic grafts commonly used in cardiovascular surgery is a major complication. We examined whether pretreatment of the graft with heparin reduces the risk of early thrombosis. A circuit was assembled to compare two pairs of shunts simultaneously in the same animal. The study shunts were pretreated with heparin. After 2 hours of circulation, clot formation was evaluated by image analysis techniques. The pretreated grafts had fewer blood clots adhered to the surface by direct visual inspection. The image analysis showed 5 vs. 39 clots, 0.01% vs. 1.8% clotted area, and 62 vs. 563

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11

Sohn, Sung-Hwa, Tae-Hee Kim, Tae-Sik Kim, et al. "Evaluation of 3D Templated Synthetic Vascular Graft Compared with Standard Graft in a Rat Model: Potential Use as an Artificial Vascular Graft in Cardiovascular Disease." Materials 14, no. 5 (2021): 1239. http://dx.doi.org/10.3390/ma14051239.

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Although the number of vascular surgeries using vascular grafts is increasing, they are limited by vascular graft-related complications and size discrepancy. Current efforts to develop the ideal synthetic vascular graft for clinical application using tissue engineering or 3D printing are far from satisfactory. Therefore, we aimed to re-design the vascular graft with modified materials and 3D printing techniques and also demonstrated the improved applications of our new vascular graft clinically. We designed the 3D printed polyvinyl alcohol (PVA) templates according to the vessel size and shape

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12

Antonova, Larisa, Vladimir Silnikov, Victoria Sevostyanova, et al. "Biocompatibility of Small-Diameter Vascular Grafts in Different Modes of RGD Modification." Polymers 11, no. 1 (2019): 174. http://dx.doi.org/10.3390/polym11010174.

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Modification with Arg-Gly-Asp (RGD) peptides is a promising approach to improve biocompatibility of small-calibre vascular grafts but it is unknown how different RGD sequence composition impacts graft performance. Here we manufactured 1.5 mm poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/poly(ε-caprolactone) grafts modified by distinct linear or cyclic RGD peptides immobilized by short or long amine linker arms. Modified vascular prostheses were tested in vitro to assess their mechanical properties, hemocompatibility, thrombogenicity and endothelialisation. We also implanted these grafts into ra

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13

Russu, Eliza, Adrian Vasile Mureșan, Bogdan Andrei Cordoș, Constantin Copotoiu, and Ovidiu Simion Cotoi. "Morpho-Pathological Review on the Healing of Synthetic Vascular Grafts." Acta Medica Marisiensis 62, no. 1 (2016): 33–40. http://dx.doi.org/10.1515/amma-2015-0098.

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AbstractObjective: Tissue integration of vascular grafts partially depends on the host response to injury, which immediately begins after implantation and restoration of the circulation. In an infected environment, the inflammation changes the incorporation patterns. The aim of the study was to observe the tissue incorporation process, in a normal and an infected environment. Methods: We have created an experimental model by performing subfascial implantation of four types of vascular grafts, in rats (woven Dacron®, knitted Dacron®, silver coated Dacron®and expanded Polytetrafloroethylene - eP

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14

Sackman, Jill E., Michael B. Freeman, Mark G. Petersen, Zuhair Allebban, Glenn P. Niemeyer, and Clinton D. Lothrop. "Synthetic Vascular Grafts Seeded with Genetically Modified Endothelium in the Dog: Evaluation of the Effect of Seeding Technique and Retroviral Vector on Cell Persistence in Vivo." Cell Transplantation 4, no. 2 (1995): 219–35. http://dx.doi.org/10.1177/096368979500400206.

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Unique characteristics of endothelium make it an attractive target cell for gene transfer. Genetically modified endothelial cells (ECs) seeded on synthetic vascular grafts offer the potential to control neointimal hyperplasia, decrease graft thrombogenicity and improve small diameter graft patency. This study addresses the issue of synthetic vascular graft colonization with endothelial cells transduced with noninducible retroviral marker genes in the dog. Autologous endothelial cells were enzymatically harvested and transduced with either the bacterial NeoR gene or human growth hormone gene us

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15

Karrer, L., J. Duwe, A. H. Zisch, et al. "PPS-PEG Surface Coating to Reduce Thrombogenicity of Small Diameter ePTFE Vascular Grafts." International Journal of Artificial Organs 28, no. 10 (2005): 993–1002. http://dx.doi.org/10.1177/039139880502801006.

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Aims Patency failure of small vascular synthetic grafts is still a major problem for coronary and peripheral revascularization. Thus, three new surface coatings of small synthetic grafts were tested in an acute pig model to evaluate their thrombogenicity (extracorporeal arterio-venous shunt) and in a chronic rat model to evaluate the tissue reaction they induced (subcutaneous implantation). Methods In five domestic pigs (25–30 kg) an extracorporeal femoro-femoral arterio-venous shunt model was used. The study protocol included first a non-heparinized perfusion sequence followed by graft perfus

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16

Chew, Chee Ho, Bo-Long Sheu, Amanda Chen, et al. "Tissue-Engineered Vascular Graft with Co-Culture of Smooth Muscle Cells and Human Endothelial Vein Cells on an Electrospun Poly(lactic-co-glycolic acid) Microtube Array Membrane." Membranes 11, no. 10 (2021): 732. http://dx.doi.org/10.3390/membranes11100732.

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Coronary artery disease is one of the major diseases that plagues today’s modern society. Conventional treatments utilize synthetic vascular grafts such as Dacron® and Teflon® in bypass graft surgery. Despite the wide adaptation, these synthetic grafts are often plagued with weaknesses such as low hemocompatibility, thrombosis, intimal hyperplasia, and risks of graft infection. More importantly, these synthetic grafts are not available at diameters of less than 6 mm. In view of these challenges, we strived to develop and adapt the electrospun Poly Lactic-co-Glycolic Acid (PLGA) Microtube Array

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17

Hung, Huey-Shan, and Shan-hui Hsu. "Surface Modification by Nanobiomaterials for Vascular Tissue Engineering Applications." Current Medicinal Chemistry 27, no. 10 (2020): 1634–46. http://dx.doi.org/10.2174/0929867325666180914104633.

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Treatment of cardiovascular disease has achieved great success using artificial implants, particularly synthetic-polymer made grafts. However, thrombus formation and restenosis are the current clinical problems need to be conquered. New biomaterials, modifying the surface of synthetic vascular grafts, have been created to improve long-term patency for the better hemocompatibility. The vascular biomaterials can be fabricated from synthetic or natural polymers for vascular tissue engineering. Stem cells can be seeded by different techniques into tissue-engineered vascular grafts in vitro and imp

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18

Feldman, H. I., S. Kobrin, and A. Wasserstein. "Hemodialysis vascular access morbidity." Journal of the American Society of Nephrology 7, no. 4 (1996): 523–35. http://dx.doi.org/10.1681/asn.v74523.

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Complications associated with hemodialysis vascular access represent one of the most important sources of morbidity among ESRD patients in the United States today. In this study, new data on the magnitude and growth of vascular access-related hospitalization in the United States is presented, demonstrating that the costs of this morbidity will soon exceed $1 billion per yr. This study also reviews published literature on the morbidity associated specifically with native arteriovenous fistulae, polytetrafluoroethylene bridge grafts, and permanent central venous catheters. Next, new information

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19

Gage, Shawn M., and Jeffrey H. Lawson. "Bioengineered hemodialysis access grafts." Journal of Vascular Access 18, no. 1_suppl (2017): S56—S63. http://dx.doi.org/10.5301/jva.5000692.

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There is a need for bioengineered therapies to improve the overall health of the growing and aging world population. Patients with renal failure have a life-long requirement for a durable form of hemodialysis vascular access. In this article, we review the history of tissue engineering as it pertains to bioengineered grafts and vessels for hemodialysis access. Over the years, various strategies have been utilized to develop ideal, humanized vessels for vascular replacement such as fixation of animal or human vessels, cell seeding of synthetic materials, and the synthesis of completely autologo

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20

Yalcin Enis, Ipek, and Telem Gok Sadikoglu. "Design parameters for electrospun biodegradable vascular grafts." Journal of Industrial Textiles 47, no. 8 (2016): 2205–27. http://dx.doi.org/10.1177/1528083716654470.

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The inadequacies of the currently used small diameter, non-biodegradable synthetic grafts prompt researchers to focus on the design parameters of vascular grafts. Since the purpose is to mimic the native vessel as far as possible, the design parameters are mainly determined by the layout of cell types and proteins in the layers of the vessels and the nano and micro structure of their environments. In consequence of this, the complex structure of native vessels has become a broad source of inspiration for researchers. Electrospun fibrous scaffolds with their well accepted advantages are promisi

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21

Tatterton, Mark, Stacy-Paul Wilshaw, Eileen Ingham, and Shervanthi Homer-Vanniasinkam. "The Use of Antithrombotic Therapies in Reducing Synthetic Small-Diameter Vascular Graft Thrombosis." Vascular and Endovascular Surgery 46, no. 3 (2012): 212–22. http://dx.doi.org/10.1177/1538574411433299.

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Background. Thrombosis of synthetic small-diameter bypass grafts remains a major problem. The aim of this article is to review the antithrombotic strategies that have been used in an attempt to reduce graft thrombogenicity. Methods. A PubMed/MEDLINE search was performed using the search terms “vascular graft thrombosis,” “small-diameter graft thrombosis,” “synthetic graft thrombosis” combined with “antithrombotic,” “antiplatelet,” “anticoagulant,” “Dacron,” “PTFE,” and “polyurethane.” Results. The majority of studies on antithrombotic therapies have used either in vitro models or in vivo anima

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22

Rosalia, Mariella, Priusha Ravipati, Pietro Grisoli, et al. "Tobramycin Supplemented Small-Diameter Vascular Grafts for Local Antibiotic Delivery: A Preliminary Formulation Study." International Journal of Molecular Sciences 22, no. 24 (2021): 13557. http://dx.doi.org/10.3390/ijms222413557.

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Peripheral artery occlusive disease is an emerging cardiovascular disease characterized by the blockage of blood vessels in the limbs and is associated with dysfunction, gangrene, amputation, and a high mortality risk. Possible treatments involve by-pass surgery using autologous vessel grafts, because of the lack of suitable synthetic small-diameter vascular prosthesis. One to five percent of patients experience vascular graft infection, with a high risk of haemorrhage, spreading of the infection, amputation and even death. In this work, an infection-proof vascular graft prototype was designed

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23

Schneider, Peter A., Harry F. Kotz[eacute], Anthon du P. Heyns, and Stephen R. Hanson. "Thromboembolic potential of synthetic vascular grafts in baboons." Journal of Vascular Surgery 10, no. 1 (1989): 0075–82. http://dx.doi.org/10.1067/mva.1989.vs0100075.

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Schneider, Peter A., Harry F. Kotzé, Anthon du P. Heyns, and Stephen R. Hanson. "Thromboembolic potential of synthetic vascular grafts in baboons." Journal of Vascular Surgery 10, no. 1 (1989): 75–82. http://dx.doi.org/10.1016/0741-5214(89)90288-7.

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25

Stowell, Chelsea E. T., and Yadong Wang. "Quickening: Translational design of resorbable synthetic vascular grafts." Biomaterials 173 (August 2018): 71–86. http://dx.doi.org/10.1016/j.biomaterials.2018.05.006.

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26

Absood, Afaf, Akira Furutani, Tsutomu Kawamura, and Linda M. Graham. "Differential PDGF secretion by graft and aortic SMC in response to oxidized LDL." American Journal of Physiology-Heart and Circulatory Physiology 283, no. 2 (2002): H725—H732. http://dx.doi.org/10.1152/ajpheart.00060.2002.

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Smooth muscle cells (SMC) from prosthetic vascular grafts constitutively secrete higher levels of platelet-derived growth factor-AA (PDGF-AA) than aortic SMC. Lipid oxidation products accumulate in grafts and may stimulate PDGF production. The effect of oxidized low-density lipoprotein (oxLDL) on PDGF-AA secretion by aortic and graft SMC was compared. SMC isolated from canine thoracic aorta or Dacron thoracoabdominal grafts ( n = 10) were incubated with native LDL or oxLDL (0–400 μg/ml) for 72 h. PDGF-AA in the conditioned medium was measured with enzyme-linked immunosorbent assay. OxLDL incre

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Gade, Piyusha S., Keewon Lee, Blaise N. Pfaff, Yadong Wang, and Anne M. Robertson. "Degradation and erosion mechanisms of bioresorbable porous acellular vascular grafts: an in vitro investigation." Journal of The Royal Society Interface 14, no. 132 (2017): 20170102. http://dx.doi.org/10.1098/rsif.2017.0102.

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A fundamental mechanism of in situ tissue regeneration from biodegradable synthetic acellular vascular grafts is the effective interplay between graft degradation, erosion and the production of extracellular matrix. In order to understand this crucial process of graft erosion and degradation, we conducted an in vitro investigation of grafts ( n = 4 at days 1, 4, 7, 10 each) exposed to enzymatic degradation. Herein, we provide constitutive relationships for mass loss and mechanical properties based on much-needed experimental data. Furthermore, we formulate a mathematical model to provide a phy

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Kielty, Cay M., Simon Stephan, Michael J. Sherratt, Matthew Williamson, and C. Adrian Shuttleworth. "Applying elastic fibre biology in vascular tissue engineering." Philosophical Transactions of the Royal Society B: Biological Sciences 362, no. 1484 (2007): 1293–312. http://dx.doi.org/10.1098/rstb.2007.2134.

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For the treatment of vascular disease, the major cause of death in Western society, there is an urgent need for tissue-engineered, biocompatible, small calibre artery substitutes that restore biological function. Vascular tissue engineering of such grafts involves the development of compliant synthetic or biomaterial scaffolds that incorporate vascular cells and extracellular matrix. Elastic fibres are major structural elements of arterial walls that can enhance vascular graft design and patency. In blood vessels, they endow vessels with the critical property of elastic recoil. They also influ

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Ijima, Hiroshi, Kunihiko Hirabayashi, Yuzura Sakakibara, Tatsuo Tsutsui, Toshio Mitsui, and Motokazu Hori. "Results of Femoro-Femoral Vein Bypass Grafting with Temporary Arteriovenous Fistula for Femoro-Iliac Venous Thrombosis: Differences between Operations in the Acute and Chronic Phases." Phlebology: The Journal of Venous Disease 5, no. 4 (1990): 237–44. http://dx.doi.org/10.1177/026835559000500405.

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Femoro-femoral vein bypass operation using a synthetic vascular graft with simultaneous construction of a temporary arteriovenous fistula (A-V f.) was performed in eight patients with acute femoro-iliac venous thrombosis after successful femoral thrombectomy but unsuccessful iliac thrombectomy; this operation was also performed in one patient with subacute thrombosis of the iliac vein and three patients with femoro-iliac post-phlebitic syndrome. Of the first nine patients who underwent the operation in the acute or subacute phase of the disease, the synthetic vascular grafts remained patent af

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Malik, Sairish, Subramanian Sundarrajan, Tanveer Hussain, Ahsan Nazir, and Seeram Ramakrishna. "Fabrication of Highly Oriented Cylindrical Polyacrylonitrile, Poly(lactide-co-glycolide), Polycaprolactone and Poly(vinyl acetate) Nanofibers for Vascular Graft Applications." Polymers 13, no. 13 (2021): 2075. http://dx.doi.org/10.3390/polym13132075.

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Small-diameter vascular grafts fabricated from synthetic polymers have found limited applications so far in vascular surgeries, owing to their poor mechanical properties. In this study, cylindrical nanofibrous structures of highly oriented nanofibers made from polyacrylonitrile, poly (lactide-co-glycolide) (PLGA), polycaprolactone (PCL) and poly(vinyl acetate) (PVAc) were investigated. Cylindrical collectors with alternate conductive and non-conductive segments were used to obtain highly oriented nanofibrous structures at the same time with better mechanical properties. The surface morphology

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Kawecka, A., A. DȨbska-Ślizien, G. Korejwo, et al. "Evaluation of Gore-Tex Graft Patency in Hemodialysis Access." Journal of Vascular Access 4, no. 2 (2003): 45–49. http://dx.doi.org/10.1177/112972980300400203.

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Aim The purpose of this retrospective study was to analyze the patency and complications of Gore-Tex grafts used in hemodialysis (HD) access. Methods In the last 16 years, 1649 surgical procedures were performed on 655 patients to ensure and maintain permanent HD access. The study group consisted of 64 HD patients on whom 81 vascular synthetic PTFE Goretex grafts were performed. There were 28 males and 36 females, 3 of them were children (4.7%). Mean age was 54.2 years (range 15–77). Two types of Gore-Tex prosthesis were used: Diastat and Stretch. All grafts were implanted in the upper extremi

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Kannan, Ruben Y., Sandip Sarkar, Jalaledin Mirzay-Razaz, and Alexander M. Seifalian. "New vessels: Vascular tissue engineering." Biochemist 29, no. 1 (2007): 12–15. http://dx.doi.org/10.1042/bio02901012.

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The use of vascular bypass grafts in patients is not new. The high prevalence of atherosclerosis has seen them being used in the treatment of some of the 800 000 cases of myocardial infarction in the UK. So, is there a need for tissue-engineered blood vessels if there is a functional prosthetic alternative? While this may hold true for vessels with high-blood-flow rates1, the patency rates of poly(ethylene terephthalate) (Dacron®) and expanded polytetrafluoroethylene (ePTFE) grafts are less satisfactory at lower flow rates. Given the limitations with synthetic materials alone, a biological or

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Yalcin Enis, Ipek, Telem Gok Sadikoglu, Jana Horakova, and David Lukas. "The post-morphological analysis of electrospun vascular grafts following mechanical testing." Journal of Polymer Engineering 38, no. 6 (2018): 525–35. http://dx.doi.org/10.1515/polyeng-2017-0157.

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AbstractVascular grafts provide promising scaffolds for patients recuperating from cardiovascular diseases. Since it is necessary to mimic the native vessel in order to overcome the limitations of currently employed synthetic prostheses, researchers are tending to focus on the design of electrospun biodegradable multi-layer scaffolds which involves varying either the polymer type or constructional properties in each layer which, in turn, reveals the importance of layer interactions and their composite effect on the final multi-layer graft. This study describes the fabrication of biodegradable

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Pislaru, S. V. "Magnetic Forces Enable Rapid Endothelialization of Synthetic Vascular Grafts." Circulation 114, no. 1_suppl (2006): I—314—I—318. http://dx.doi.org/10.1161/circulationaha.105.001446.

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35

Cardozo, M. A., A. D. Frankini, and T. P. Bonamigo. "Use of Superficial Femoral Vein in the Treatment of Infected Aortoiliofemoral Prosthetic Grafts." Cardiovascular Surgery 10, no. 4 (2002): 304–10. http://dx.doi.org/10.1177/096721090201000403.

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Purpose: To assess the use of the superficial femoral vein for the reconstruction of the aortoiliofemoral sector in the treatment of prosthetic infections. Methods: From December 1995 to November 1999, 12 patients with infection involving a synthetic vascular prosthesis were submitted to thirteen surgical procedures involving partial or total resection of a synthetic vascular prosthesis and restoration of arterial flow with an in situ femoral vein. Results: The overall operative mortality rate was 15.3% (2 out of 3 patients who underwent total graft replacement and 0 out of 9 patients who unde

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Senokosova, E. A., E. O. Krivkina, L. V. Antonova, and L. S. Barbarash. "Biodegradable small-diameter vascular graft: types of modification with bioactive molecules and RGD peptides." Russian Journal of Transplantology and Artificial Organs 22, no. 1 (2020): 86–96. http://dx.doi.org/10.15825/1995-1191-2020-1-86-96.

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The need for small-diameter grafts for replacing the damaged area of the blood pool is still very high. These grafts are very popular for coronary artery bypass grafting. Polymeric synthetic grafts are an alternative to autografts. A promising area of tissue engineering is the creation of a biodegradable graft. It can serve as the basis for de novo generation of vascular tissue directly in the patient’s body. Optimization of the polymer composition of products has led to improved physicomechanical and biocompatible properties of the products. However, the improvements are still far from needed

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Pecoraro, Felice, Mayur Krishnaswamy, Johnny Steuer, et al. "Predilation technique with balloon angioplasty to facilitate percutaneous groin access of large size sheath through scar tissue." Vascular 25, no. 4 (2017): 396–401. http://dx.doi.org/10.1177/1708538116688786.

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Purpose Percutaneous remote access for endovascular aortic repair is an advantageous alternative to open access. Previous surgery in the femoral region and the presence of synthetic vascular grafts in the femoral/iliac arteries represent major limitations to percutaneous remote access. The aim of this study was to evaluate an original technique used for enabling percutaneous remote access for thoracic or abdominal endovascular aortic repair in patients with scar tissue and/or a vascular graft in the groin. Methods Twenty-five consecutive patients with a thoracic (11/25; 44%) or an aortic aneur

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BACALBASA, Nicolae, Irina BALESCU, Claudia STOICA, et al. "Autologous grafts for vascular resections after extended resections for locally advanced or borderline resectable pancreatic tumors." Romanian Journal of Medical Practice 17, no. 2 (2022): 76–79. http://dx.doi.org/10.37897/rjmp.2022.2.6.

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Once the surgical techniques improved, vascular resections have been proposed in order to increase the radicality in borderline or locally advanced pancreatic cancer. Traditionally, vascular reconstructions in such cases have been performed by using synthetic grafts; however, these prostheses have been associated with significant complications such as infection, thrombosis or leaks, leading to a very difficult postoperative recovery. Therefore, attention was focused on replacing these artificial materials with biological ones such as cadaveric grafts, autologous grafts or even animal grafts. T

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Domínguez-Robles, Juan, Luis Diaz-Gomez, Emilia Utomo, et al. "Use of 3D Printing for the Development of Biodegradable Antiplatelet Materials for Cardiovascular Applications." Pharmaceuticals 14, no. 9 (2021): 921. http://dx.doi.org/10.3390/ph14090921.

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Small-diameter synthetic vascular grafts are required for surgical bypass grafting when there is a lack of suitable autologous vessels due to different reasons, such as previous operations. Thrombosis is the main cause of failure of small-diameter synthetic vascular grafts when used for this revascularization technique. Therefore, the development of biodegradable vascular grafts capable of providing a localized and sustained antithrombotic drug release mark a major step forward in the fight against cardiovascular diseases, which are the leading cause of death globally. The present paper descri

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Jeong, YeJin, Yuan Yao, and Evelyn K. F. Yim. "Current understanding of intimal hyperplasia and effect of compliance in synthetic small diameter vascular grafts." Biomaterials Science 8, no. 16 (2020): 4383–95. http://dx.doi.org/10.1039/d0bm00226g.

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Chiu, Yung-Cheng, Yu-Fang Shen, Alvin Kai-Xing Lee, Shu-Hsien Lin, Yu-Chen Wu, and Yi-Wen Chen. "3D Printing of Amino Resin-based Photosensitive Materials on Multi-parameter Optimization Design for Vascular Engineering Applications." Polymers 11, no. 9 (2019): 1394. http://dx.doi.org/10.3390/polym11091394.

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Cardiovascular diseases are currently the most common cause of death globally and of which, the golden treatment method for severe cardiovascular diseases or coronary artery diseases are implantations of synthetic vascular grafts. However, such grafts often come with rejections and hypersensitivity reactions. With the emergence of regenerative medicine, researchers are now trying to explore alternative ways to produce grafts that are less likely to induce immunological reactions in patients. The main goal of such studies is to produce biocompatible artificial vascular grafts with the capabilit

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Ross, John R. "Insertion of Short Introducer Sheaths into a Polyurethane Vascular Access Graft for Immediate Hemodialysis Access." Journal of Vascular Access 4, no. 2 (2003): 62–67. http://dx.doi.org/10.1177/112972980300400206.

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While native AV fistulae are considered the “gold standard” for hemodialysis patients in need of long-term access, synthetic grafts are the best option for patients who are not candidates for an AV fistula. While AV fistulae should be allowed to mature for 3 – 4 months prior to cannulation, PTFE grafts may be cannulated 14 days after placement. Despite the benefit of earlier cannulation in PTFE graft recipients compared to AV fistulae patients, one critical limitation is that immediate post-operative cannulation is not possible. The self-sealing nature of the polyurethane Vectra® Graft overcom

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Lee, Bob S. L., Nianji Yang, Miguel Santos, et al. "Truncated vascular endothelial cadherin enhances rapid endothelialization of small diameter synthetic vascular grafts." Materials Today Advances 14 (June 2022): 100222. http://dx.doi.org/10.1016/j.mtadv.2022.100222.

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Reddy, Daniel J. "Atherosclerosis in vascular grafts for peripheral vascular disease part 2. Synthetic arterial prostheses." Journal of Vascular Surgery 6, no. 3 (1987): 324. http://dx.doi.org/10.1016/0741-5214(87)90263-1.

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Lawson, Jeffrey. "Engineered Blood Vessels." Blood 130, Suppl_1 (2017): SCI—12—SCI—12. http://dx.doi.org/10.1182/blood.v130.suppl_1.sci-12.sci-12.

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Abstract The field of tissue engineering has has made significant progress in the past 20 years. Of the many tissues and organs in development, the area of vascular tissue engineering is now one of the most mature. In that regard, we have developed a novel tissue engineered vascular graft (human acellular vessel [HAV]) that addresses many of the limitations of native vein harvest and the performance of both synthetic ePTFE and autologous vein grafts. The HAV is manufactured in a laboratory by culturing human vascular cells within a biodegradable scaffold that forms a mechanically robust tissue

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Porile, J. L., and M. Richter. "Preservation of vascular access." Journal of the American Society of Nephrology 4, no. 4 (1993): 997–1003. http://dx.doi.org/10.1681/asn.v44997.

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Preservation of vascular access is critical in the long-term successful management of hemodialysis patients. Dialysis access abnormalities are the most common cause of hospitalization in this patient group, and access problems can increase the morbidity and cost involved in the care of these patients. Native fistulas are preferable to synthetic grafts because of longer survival and a lower complication rate. Venous outflow stenosis is the most common site of obstruction in a failing graft. The pathophysiology of access failure is poorly understood, but it seems to be related to intimal hyperpl

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Meyer, Schweiger, and Lang. "Der extraanatomische Bypass zur Behandlung einer Gefäßprotheseninfektion in der Leiste." Vasa 28, no. 4 (1999): 283–88. http://dx.doi.org/10.1024/0301-1526.28.4.283.

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Background: Infection of an alloplastic vascular graft is a serious complication and often involves the groin. We propose a therapeutic concept using extraanatomic bypass to avoid the septic groin in case of an infected alloplastic vascular reconstruction. Patients and methods: The course of 25 patients (18 men, 7 women, mean age 61 years) with a grade III inguinal infection following placement of an aortic or femoro-distal synthetic graft made of Dacron or PTFE was analysed. The treatment consisted of excision of the infected graft material and extraanatomic reconstruction with ringed PTFE gr

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Byrne, Oisín, Fergal Coulter, Ellen T. Roche, and Eoin D. O'Cearbhaill. "In silico design of additively manufacturable composite synthetic vascular conduits and grafts with tuneable compliance." Biomaterials Science 9, no. 12 (2021): 4343–55. http://dx.doi.org/10.1039/d0bm02169e.

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Prendiville, E. J., S. Laliberté Verdon, K. E. Gould, K. Ramberg, R. J. Connolly та A. D. Callow. "Correlation of γ-radioactivity and Scanning Electron Microscopy in measurement of retention of 111Indium-labeled canine endothelial cells on synthetic vascular grafts". Proceedings, annual meeting, Electron Microscopy Society of America 47 (6 серпня 1989): 886–87. http://dx.doi.org/10.1017/s0424820100156419.

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Endothelial cell (EC) seeding is postulated as a mechanism of improving patency in small caliber vascular grafts. However the majority of seeded EC are lost within 24 hours of restoration of blood flow in previous canine studies . We postulate that the cells have insufficient time to fully develop their attachment to the graft surface prior to exposure to hemodynamic stress. We allowed EC to incubate on fibronectin-coated ePTFE grafts for four different time periods after seeding and measured EC retention after perfusion in a canine ex vivo shunt circuit.Autologous canine EC, were enzymaticall

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Jabłońska, Beata, Robert Król, and Sławomir Mrowiec. "Vascular Resection in Pancreatectomy—Is It Safe and Useful for Patients with Advanced Pancreatic Cancer?" Cancers 14, no. 5 (2022): 1193. http://dx.doi.org/10.3390/cancers14051193.

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Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with poor prognosis and increased incidence. Surgical resection R0 remains the most important treatment to prolong survival in PDAC patients. In borderline and locally advanced cancer, vascular resection and reconstruction during pancreatectomy enables achieving R0 resection. This study is a comprehensive review of the literature regarding the role of venous and arterial resection with vascular reconstruction in the treatment of pancreatic cancer. The literature review is focused on the use of venous and arterial resection with immedi

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