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Journal articles on the topic 'Systemic lupus erythematoses'

Author: Grafiati

Published: 4 June 2021

Last updated: 28 July 2025

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1

Chinnusamy, Manokaran, Ram Arvind Viswanathan, Sathiyanarayanan Janakiraman, and Roshna Elayidath. "Drug-Induced Lupus Erythematosus Associated with Proton Pump Inhibitor." Journal of Health and Allied Sciences NU 10, no. 03 (2020): 132–34. http://dx.doi.org/10.1055/s-0040-1716601.

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AbstractDrug-induced lupus erythematosus is an autoimmune phenomenon where the drug exposure leads to the development of systemic lupus erythematous like clinical features. Drug-induced lupus erythematosus can be divided into systemic lupus erythematous, subacute cutaneous lupus erythematous, and chronic cutaneous lupus erythematous. Here, we report a case of a 29-year-old female presented with systemic lupus erythematous due to chronic use of proton pump inhibitors, which is considered to be very rare.

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Garbelini-Lima, Cleide, Gabriela Evangelista de Almeida, Sidharta Quércia Gabdelha, Andrea Cavalcante de Souza, Mara Lúcia Gomes de Souza, and Virginia Vilasboas Figueiras. "Discoid Lupus Erythematosus of the Scalp in a Patient with Systemic Lupus Erythematosus: A Case Report with Complete Hair Regrowth." Journal of the Portuguese Society of Dermatology and Venereology 79, no. 2 (2021): 155–58. http://dx.doi.org/10.29021/spdv.79.2.1283.

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Scalp involvement with hair loss is common in systemic lupus erythematosus. Discoid lupus erythematosus may cause scarring alopecia, characterized by well-delimited erythematous plaques with scales, follicular hyperkeratosis and atrophy, which is considered a trichological emergency. Early diagnosis and treatment are necessary in order to prevent permanent hair loss. We describe a 44 years’ old female patient with systemic lupus erythematosus for 4 years, with multiple areas of occipitoparietal alopecia, erythematous plaques, atrophy, scales and some bloody crusts. Trichoscopy, histopathology

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Paul, Sujat. "Lupus With Pregnancy : Beyond the Basics." Journal of Chittagong Medical College Teachers' Association 23, no. 1 (2012): 53–56. http://dx.doi.org/10.3329/jcmcta.v23i1.51898.

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Pregnancy in patients with systemic lupus erythematosus is associated with a high risk of maternal disease exacerbation and adverse fetal outcome. This review summarizes recent published findings on lupus pregnancy. Literature review: The literature has profound agreement on thefact that, for most women with inactive and stable systemic lups erythematousus, pregnancy is safe for both mother and fetus. The main risk factors for adverse pregnancy course and outcome are active disease, nephritis with proteinuria, hypertension and maternal serum antibodies to SS-A/Ro, SS-B/La, cardiolipin, 2-glyco

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4

Shenoy, Manjunath M., Goutham Kilaru, Ashmiya Razak, and Malcolm Pinto. "Atypical dermatophytosis in a case of systemic lupus erythematosus." Our Dermatology Online 11, e (2020): e165.1-e165.3. http://dx.doi.org/10.7241/ourd.2020e.165.

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Systemic lupus erythematosus (SLE) is a multiorgan autoimmune connective tissue disease with many muco-cutaneous manifestations. We report a case of SLE on treatment presented with scaly erythematous plaques on the trunk and extremities and diffuse scaly erythematous macular lesions on the face resembling cutaneous lupus erythematosus. Laboratory evaluation established a diagnosis of tinea corporis with faciei. He responded to long term itraconazole therapy. This case focuses on the modification of tinea in an autoimmune disorder on immunosuppressive therapy and its therapeutic implications.

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Huzairi Sani, Nada Syazana, and Malek Faris Riza Feisal. "A different kind of skin presentation in Systemic Lupus Erythematosus (SLE): A case report." Asian Journal of Medicine and Biomedicine 4, no. 1 (2020): 42–46. http://dx.doi.org/10.37231/ajmb.2020.4.1.329.

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Erythema nodosum is a septal panniculitis which is a variant of chronic cutaneous lupus erythematosus (CCLE). It is further classified in the group of Lupus Erythematous Panniculitis (LEP).[1] The most frequent cutaneous manifestations include indurated plaques, subcutaneous nodules and sometimes ulcerations. The lesions occur predominantly on the face, upper arms, upper trunk, breasts, buttocks and thighs.[2] They occur most frequently in adult females and do not typically manifest cutaneously in Systemic Lupus Erythematosus (SLE).[3] In this case report, we discuss a young gentleman who pres

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Richter, JG, O. Sander, M. Schneider, and P. Klein-Weigel. "Diagnostic algorithm for Raynaud’s phenomenon and vascular skin lesions in systemic lupus erythematosus." Lupus 19, no. 9 (2010): 1087–95. http://dx.doi.org/10.1177/0961203310374304.

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Skin discolorations and skin lesions due to vascular pathologies are common clinical features in systemic lupus erythematosus. A variety of clinical manifestations such as Raynaud’s phenomenon, acrocyanosis, livedo patterns, erythematous or violaceous macules and papules or necrosis are triggered by heterogeneous pathophysiological mechanisms such as vasospasm, vasculitis or thromboembolism. A standardized macro- and microvascular assessment is necessary to establish the correct diagnosis. We describe and illustrate common clinical features of vascular skin manifestations in systemic lupus ery

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Khabba, Chaimae Ait, Basma Karrakchou, Marwa Asermouh, Laila Berbich, Kaoutar Znati, and Karima Senouci. "Comedonal variant of chronic cutaneous lupus erythematosus on the nose." Our Dermatology Online 14, no. 3 (2023): 298–300. http://dx.doi.org/10.7241/ourd.20233.14.

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A thirty-year-old patient presented with an erythematous papule on the left nostril evolving for ten months. A clinical examination revealed an infiltrated, erythematous, well-limited plaque with a raised border, covered with multiple open and closed comedones. On dermoscopy, there was an erythematous background with some fine telangiectasias and horny plugs at the follicular orifices. A skin biopsy was performed, revealing orthokeratotic hyperkeratosis sinking into the follicular orifices dilated by sebum clumps with basal vacuolation associated with a subepidermal and periadnexal/perivascula

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8

N, Habib. "Review Article: Systemic Lupus Erythematosus." Open Access Journal of Microbiology & Biotechnology 5, no. 1 (2020): 1–4. http://dx.doi.org/10.23880/oajmb-16000158.

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Systemic lupus erythematosus or SLE is a persistent heterogeneous autoimmune disease that affects multisystem of the body. It is distinguished by acute and chronic inflammation of various tissues and even organs of the body principally the skin and joints. Systemic lupus erythematosus is a multisystem disorder and hence, it can affect any tissues, organs and even systems of the body. There are few categories of lupus for instance, lupus dermatitis or cutaneous lupus erythematosus (CLE) that affects the skin and causes malar rash, discoid lupus erythematosus (DLE) as well as systemic lupus eryt

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9

Franjic, Sinisa. "Systemic Lupus Erythematosus in Gynecology." International Journal of Reproductive Research 1, no. 1 (2022): 01–03. http://dx.doi.org/10.58489/2836-2225/005.

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Systemic lupus erythematosus is a chronic autoimmune disease that can affect various organs and parts of the body, especially the skin, joints, blood, kidneys, and central nervous system. Systemic lupus erythematosus is not a contagious disease, it is an autoimmune disease in which the immune system loses the ability to distinguish foreign from the patient's own tissues and cells. The immune system makes mistakes and produces, among other things, autoantibodies that recognize their own cells as foreign and attack them. The result is an autoimmune reaction that causes inflammation. Inflammation

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10

Mrabat, Samia, Hanane aybay, Zakia Douhi, Sara Elloudi, Fatima Zahra Mernissi, and Mouna Rimani. "Cutaneous lupus tumidus: An unusual unilateral presentation." Our Dermatology Online 12, no. 2 (2021): 151–52. http://dx.doi.org/10.7241/ourd.20212.10.

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Lupus tumidus is a rare subtype of chronic cutaneous lupus erythematosus characterized by erythema and bright urticarial erythematous and violaceous lesions on sun-exposed areas that heal without leaving scars. Lupus tumidus follows a benign and intermittent clinical course and is rarely associated with systemic lupus erythematosus. Treatment involves photoprotection, topical corticosteroids, and antimalarials. We report the case of a 42-year-old patient with an atypical unilateral form of lupus tumidus successfully treated with the administration of hydroxychloroquine in combination with phot

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11

Baharudin, Ruziana, Nur Suhaila Idris, Juliawati Muhammad, and Wan Noor Hasbee Wan Abdullah. "A Case Report of Male Systemic Lupus Erythematous with Antinuclear Antibodies-Negative: A Challenging Diagnosis." Korean Journal of Family Medicine 43, no. 2 (2022): 150–54. http://dx.doi.org/10.4082/kjfm.20.0211.

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Systemic lupus erythematosus (SLE) is a connective tissue disease of unknown etiology that predominantly affects women of childbearing age. We report a case of male systemic lupus erythematous with antinuclear antibodies and typical clinical presentations of multiple skin lesions, polyarticular joint pain, fatigue, anorexia, and hair loss. Full evaluations were used to establish a diagnosis of SLE. The lower prevalence of SLE among males and antinuclear antibody-negative patients poses a great challenge for diagnosis. Therefore, as primary care doctors, we need to have a high suspicion of syst

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12

Parimala L and Vanitha R. "Assess the knowledge regarding the risk of cardiovascular diseases among systemic lupus erythematosus patient." International Journal of Research in Pharmaceutical Sciences 10, no. 4 (2019): 2739–41. http://dx.doi.org/10.26452/ijrps.v10i4.1539.

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India is a country with different beliefs like religious, cultural, variation and economic diversity in the health care setting. SLE is a long term disease which involves multisystem, leading to loss of immune tolerance to own antigens. The study aims to assess the knowledge regarding the risk of cardiovascular diseases among systemic lupus erythematous patient at Saveetha Medical College and Hospital. A quantitative research approach was adopted with convenient sampling technique to select 60 patients with systemic lupus erythematosus who attend at Saveetha Medical College and Hospital. Data

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13

Borizanova-Petkova, A., D. Somleva, E. Kinova, V. Koleva, Y. Zdravkova, and A. Goudev. "Lupus cardiomyopathy in young woman with high lupus activity." Bulgarian Cardiology 30, no. (4) (2024): 122–29. https://doi.org/10.3897/bgcardio.30.e140680.

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Systemic lupus erythematosus is a chronic autoimmune disorder affecting predominantly young women. Cardiac involvement in systemic lupus erythematosus is common and the typical manifestations are pericarditis, myocarditis, valvular disease, coronary artery disease, cardiac arrhythmias, and congestive heart failure. Clinical lupus myocarditis typically occurs early during lupus, in the context of high disease activity. It may present as an acute illness or have a chronic course with the development of cardiomyopathy. We present a clinical case of young patient who developed a severe dilated car

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14

Salem, Bouomrani, Riahi Sihem, and Ben Houchet Marwa. "Bullous systemic lupus erythematosus: exceptional and challenging presentation." Iberoamerican Journal of Medicine 2, no. 4 (2020): 388–90. https://doi.org/10.5281/zenodo.3965555.

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Vesiculobullous lesions can be developed by less than 5% of patients with systemic lupus erythematosus (SLE). Among these lesions, bullous systemic lupus erythematosus (BSLE) is one of the rarest and most challenging cutaneous presentations of the disease. Its frequency in the largest series of 5149 patients with cutaneous lupus was 0.19%, and the majority of cases are reported as sporadic observation or small series not exceeding ten cases. We report the original observation of BSLE revealing SLE in 32-year-old Tunisian Woman. This atypical presentation of cutaneous lupus deserves to be known

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15

Chottawornsak, N., P. Rodsaward, S. Suwannachote, et al. "Skin signs in juvenile- and adult-onset systemic lupus erythematosus: clues to different systemic involvement." Lupus 27, no. 13 (2018): 2069–75. http://dx.doi.org/10.1177/0961203318805851.

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Objective We aim to explore the differences of skin signs between juvenile- and adult-onset systemic lupus erythematosus and to identify their associations to the development of systemic involvement. Methods A retrospective chart review of 377 systemic lupus erythematosus patients was performed. Results In total, 171 patients with juvenile systemic lupus erythematosus and 206 with adult systemic lupus erythematosus were studied. All patients were of Southeast Asian descent. The mean duration of follow up was 8.18 ± 6.19 and 9.36 ± 7.68 years for juvenile systemic lupus erythematosus and adult

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16

Le, Marilyn, Payvand Kamrani, and L. Claire Hollins. "Coexistentence of Morphea and DLE in a Patient with Beta Thalassemia Leading to a Diagnosis of Systemic Lupus Erythematous." SKIN The Journal of Cutaneous Medicine 6, no. 3 (2022): 243–45. http://dx.doi.org/10.25251/skin.6.3.11.

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Patients with autoimmune disorders are predisposed to developing a second autoimmune condition. This can be applied to cutaneous conditions as well. Morphea or localized scleroderma is an autoimmune inflammatory and fibrosing skin disorder due to increased collagen deposition.1,2 Patients with morphea are four times likelier of having a concomitant autoimmune disease.1 There have been cases of systemic lupus erythematosus (SLE) with morphea, but the co-occurrence of discoid lupus erythematosus (DLE) with morphea has been rarely reported, and never reported in patient with Beta-thalamessmia.1,2

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17

Abdushukurova, K. R., N. Sh Toshnazarova, and Sh X. Ziyadullayev. "PREDICTORS OF SEVERE SYSTEMIC LUPUS ERYTHEMATOSUS." Oriental Journal of Medicine and Pharmacology 03, no. 02 (2023): 53–59. http://dx.doi.org/10.37547/supsci-ojmp-03-02-06.

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The aim of the study was to assess the nature of lesions and to identify risk factors of lesions in our group of patients with SLE. A retrospective review of charts and case histories in the Internal Medicine Department of the SamMU’s clinic was carried out on a group of 75 patients with SLE. 225 people were included in this study: 75 in the main group (cases) and 150 in the control group (healthy controls). The results show that the presence of neuropsychiatric manifestations is a significant risk factor for lesions. Other likely risk factors for lesions include younger age at diagnosis, more

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18

Ocon, Anthony, Eduardo Avalos Sugastti, and Nananamibia Duffy. "Impressive resolution of refractory hypertrophic discoid lupus erythematosus with anifrolumab." BMJ Case Reports 17, no. 6 (2024): e258487. http://dx.doi.org/10.1136/bcr-2023-258487.

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Hypertrophic discoid lupus erythematosus is a rare variant of chronic cutaneous lupus erythematosus and is often challenging to treat. A male in his early 60s presented with diffuse erythematous, crusty, pruritic plaques on his upper and lower extremities, face, upper back, dorsal aspect of the hands and chest. He also described prolonged morning stiffness, swelling of his fingers and wrists, oral sores and Raynaud’s phenomenon. He was positive for antinuclear antibody and anti-SSA antibody and had low C3 and C4 proteins. The skin biopsy was consistent with hypertrophic discoid lupus erythemat

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Aiempanakit, K., K. Chiratikarnwong, S. Juthong, and S. Auepemkiate. "Toxic epidermal necrolysis-like acute cutaneous lupus erythematosus in a patient with progressive systemic sclerosis." Lupus 27, no. 11 (2018): 1860–63. http://dx.doi.org/10.1177/0961203318789766.

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A 60-year-old female was diagnosed with progressive systemic sclerosis and interstitial lung disease of two months’ duration. The patient was treated for Raynaud phenomenon with aspirin, nifedipine, colchicine, and naproxen. Two weeks after treatment, she developed widespread erythematous patches with blistering eruptions on the face, torso, and extremities, and also had erosion on the oral mucosa. Skin biopsy for histopathology and direct immunofluorescent studies were suggestive of lupus erythematosus. To the best of our knowledge, this is the first case of toxic epidermal necrolysis-like ac

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Guleva, D., M. Balabanova, L. Miteva, and L. Dourmishev. "Histology of Skin Alterations in Lupus Erythematosus." Acta Medica Bulgarica 49, no. 2 (2022): 28–32. http://dx.doi.org/10.2478/amb-2022-0016.

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Abstract Lupus erythematosus is an autoimmune connective tissue disorder showing a broad spectrum of clinical manifestations. The aim of this study was to assess the correlation of skin histology and different types of lupus erythematosus. Materials and methods: Fifty-one skin specimens were assessed from 39 female and 12 male patients with acute, subcutaneous and chronic lupus erythematosus, diagnosed and treated in the Department of Dermatology and Venereology, Alexandrovska University Hospital for a 4-year period. Results: Follicular hyperkeratosis, epidermal atrophy, vacuolar degeneration

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Singh, Sukhraj, Sandra Sheffield, Nisha Chowdhury, Swetha Nuthulaganti, Zareen Vaghaiwalla, and Karishma Ramsubeik. "Utilization of Rituximab for Refractory Rowell Syndrome." Case Reports in Rheumatology 2021 (July 29, 2021): 1–6. http://dx.doi.org/10.1155/2021/2727382.

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Rowell syndrome describes the occurrence of erythema multiforme-like lesions in patients with cutaneous lesions of lupus erythematosus. The clinical picture of atypical erythema multiforme-like lesions, presence of chilblains, speckled ANA pattern, anti-Ro/SSA, or anti-La/SSB antibodies, and absence of infectious or pharmacologic triggers in a patient with systemic lupus erythematosus are some of the classic clinical and serologic features. Histopathologic and serologic findings can help differentiate this process from erythema multiforme. We present a case of young woman with systemic lupus e

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Martha, Paulina Ornelas-Villalobos, Nuñez-Arriaga Diana, Nuñez-Arriaga Diana, et al. "Polymorphous Solar Eruption and its Association with Systemic Lupus Erythematosus." International Journal Of Medical Science And Clinical Research Studies 02, no. 12 (2022): 1425–28. https://doi.org/10.5281/zenodo.7404422.

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Polymorphic Light Eruption (PLE) is a dermatosis related to ultraviolet radiation (UV), which is why it occurs mainly in anatomical sites exposed to the sun. It can vary in morphology from one subject to another, however, in the same patient it is usually monomorphic and the most common form of presentation is the papular variant. There is a higher prevalence of this disorder in fair-skinned people and in women, while climate and latitude are also contributing factors. Its relationship with systemic lupus erythematosus is not very clear, but its histopathology and symptoms may be the key to un

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Voytsekhovskiy, V. V., M. V. Pogrebnaya, S. A. Goryacheva, et al. "RESPIRATORY AND NEURAL SYSTEM DAMAGE CAUSED BY SYSTEMIC LUPUS ERYTHEMATOSUS." Amur Medical Journal, no. 15-16 (2016): 117–19. http://dx.doi.org/10.22448/amj.2016.15-16.117-119.

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Kapoor, T. M., P. Mahadeshwar, S. Nguyen, et al. "Low prevalence of Pneumocystis pneumonia in hospitalized patients with systemic lupus erythematosus: review of a clinical data warehouse." Lupus 26, no. 14 (2017): 1473–82. http://dx.doi.org/10.1177/0961203317703494.

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Objective In the era of powerful immunosuppression, opportunistic infections are an increasing concern in systemic lupus erythematosus. One of the best-studied opportunistic infections is Pneumocystis pneumonia; however, the prevalence of Pneumocystis pneumonia in systemic lupus erythematosus is not clearly defined. This study evaluates the prevalence of Pneumocystis pneumonia in hospitalized systemic lupus erythematosus patients, with a focus on validating the Pneumocystis pneumonia and systemic lupus erythematosus diagnoses with clinical information. Methods This retrospective cohort study e

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Bae, E. H., S. Y. Lim, K. D. Han, et al. "Systemic lupus erythematosus is a risk factor for cancer: a nationwide population-based study in Korea." Lupus 28, no. 3 (2019): 317–23. http://dx.doi.org/10.1177/0961203319826672.

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Objective Specific differences in cancer risk have been observed between systemic lupus erythematosus patients and the general population. Although meta-analyses have estimated cancer incidence in systemic lupus erythematosus patients, results have been inconclusive. Hence, we aimed to assess malignancy risk in systemic lupus erythematosus patients, compared to the risk in the general population. Methods Systemic lupus erythematosus patients ( n = 21,016; mean age 41.67 ± 13.14 years; female 90.22%) were selected from the Korean National Health Insurance Service database between 2008 and 2014.

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Kriswiastiny, Rina, Festy Ladyani Mustofa, Syuhada Syuhada, and Reychan Gustiawan Putra. "Hubungan Aktifitas Penyakit SLE (Systemic Lupus Erythematosus) Berdasarkan Mex-Sledai Scoring Terhadap Depresi Di Komunitas Odapus Kota Bandar Lampung." MAHESA : Malahayati Health Student Journal 1, no. 4 (2021): 370–82. http://dx.doi.org/10.33024/mahesa.v1i4.3949.

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ABSTRACT: RELATIONSHIP OF SLE (SYSTEMIC LUPUS ERYTHEMATOSUS) ACTIVITIES BASED ON MEX-SLEDAI SCORING ON DEPRESSION IN ODAPUS COMMUNITIES BANDAR LAMPUNG Background: Depression is a clinical manifestation that can occur in patients with SLE and it is suspected that the level of SLE disease activity can affect these events (Nery, et al. 2007). Ironically, this section is a part that is often overlooked by many people, including the health sector. In fact, by understanding this point of view, cross-scientific collaborative treatment such as the Internal and Psychiatry Fields can be done to improve

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Magro-Checa, C., L. J. J. Beaart-van de Voorde, H. A. M. Middelkoop, et al. "Outcomes of neuropsychiatric events in systemic lupus erythematosus based on clinical phenotypes; prospective data from the Leiden NP SLE cohort." Lupus 26, no. 5 (2017): 543–51. http://dx.doi.org/10.1177/0961203316689145.

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Objective The objective of this study was to assess whether clinical and patient’s reported outcomes are associated with a different pathophysiological origin of neuropsychiatric events presenting in systemic lupus erythematosus. Methods A total of 232 neuropsychiatric events presenting in 131 systemic lupus erythematosus patients were included. Neuropsychiatric systemic lupus erythematosus diagnosis was established per event by multidisciplinary evaluation. All neuropsychiatric events were divided according to a suspected underlying pathophysiological process into one of the following: non-ne

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Cooper, Elizabeth E., Catherine E. Pisano, and Samantha C. Shapiro. "Cutaneous Manifestations of “Lupus”: Systemic Lupus Erythematosus and Beyond." International Journal of Rheumatology 2021 (May 18, 2021): 1–19. http://dx.doi.org/10.1155/2021/6610509.

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Lupus, Latin for “wolf,” is a term used to describe many dermatologic conditions, some of which are related to underlying systemic lupus erythematosus, while others are distinct disease processes. Cutaneous lupus erythematosus includes a wide array of visible skin manifestations and can progress to systemic lupus erythematosus in some cases. Cutaneous lupus can be subdivided into three main categories: acute cutaneous lupus erythematosus, subacute cutaneous lupus erythematosus, and chronic cutaneous lupus erythematosus. Physical exam, laboratory studies, and histopathology enable differentiati

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Takezawa, K., I. Ueda-Hayakawa, F. Yamazaki, N. Kambe, Y. Son, and H. Okamoto. "Successful treatment with hydroxychloroquine for systemic lupus erythematosus with cutaneous involvement accompanied by a xanthomatous reaction." Lupus 29, no. 1 (2019): 79–82. http://dx.doi.org/10.1177/0961203319890677.

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Antimalarials are usually recommended for the first-line systemic treatment of cutaneous lupus erythematosus. Alopecia in patients with discoid lupus erythematosus (DLE) is sometimes a refractory condition in spite of topical therapies. We herein described a case of DLE on the scalp with a pathological change of a xanthomatous reaction, which was successfully treated with hydroxychloroquine (HCQ). A 34-year-old woman presented with hair loss to the parietal region. She had been diagnosed with systemic lupus erythematosus (SLE) four years previously. Treatment with 30 mg/day of prednisolone (PS

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Yoon, J., T. K. Moon, K. H. Lee, and S. C. Kim. "Fatal vascular involvement in systemic lupus erythematosus following epidermolysis bullosa acquisita." Acta Dermato-Venereologica 75, no. 2 (1995): 143–46. http://dx.doi.org/10.2340/0001555575143146.

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Epidermolysis bullosa acquisita may be associated with various systemic diseases, including systemic lupus erythematosus. We describe the clinical and immunological findings in a 38-year-old women with epidermolysis bullosa acquisita and systemic lupus erythematosus. The epidermolysis bullosa acquisita preceded a dramatic flare of systemic lupus erythematosus and fatal cerebral vasculitis. If serologic evidence of lupus erythematosus develops during the course of epidermolysis bullosa acquisita, a thorough investigation is warranted to rule out potentially life-threatening systemic lupus eryth

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Anjani, I. Gusti Agung Dwi Putri, I. Wayan Eka Saputra, and Putu Dyah Widyaningsih. "Systemic lupus erythematous in men with interstitial lung pneumonia: a rare case report." International Journal of Advances in Medicine 11, no. 4 (2024): 384–88. http://dx.doi.org/10.18203/2349-3933.ijam20241633.

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Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease with unknown etiology and very diverse clinical manifestations, disease course, and prognosis. It is most common in African-American women, the prevalence being 4 per 1000 females. SLE predominantly affects young women, most presenting between 20 and 40 years of age. Male SLE is rare, with only one male patient reported per nine females. Pulmonary involvement in SLE is various. SLE-associated interstitial lung disease (ILD), while rare, is a predictor of poor prognosis. We report a 50-year-old male patient with com

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Abu-Shakra, M. "Safety of vaccination of patients with systemic lupus erythematosus." Lupus 18, no. 13 (2009): 1205–8. http://dx.doi.org/10.1177/0961203309346507.

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Live vaccines are not safe for immuno-compromised patients and should not be given to patients with systemic lupus erythematosus. In addition, all vaccines are not recommended for systemic lupus erythematosus patients when their disease is very active and mainly for patients with very active lupus nephritis. Systemic lupus erythematosus patients with quiescent or mildly active disease should be encouraged to receive vaccination according the recommendations given by the Immunization Practices Advisory Committee. Among this group of systemic lupus erythematosus patients, vaccines are safe and t

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Bae, S. C., and Y. H. Lee. "Associations between paraoxonase-1 and systemic lupus erythematosus." Lupus 28, no. 13 (2019): 1571–76. http://dx.doi.org/10.1177/0961203319884653.

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Objective The objective of this analysis was to explore associations between paraoxonase-1 levels, gene polymorphisms and systemic lupus erythematosus. Methods Meta-analyses of paraoxonase-1 levels and Q192R and L55M and polymorphisms in systemic lupus erythematosus were conducted. Results Nine articles were incorporated in our meta-analysis, which uncovered that the paraoxonase-1 level was decreased in systemic lupus erythematosus compared to control (standard mean difference = −1.626, 95% confidence interval = −2.829–−0.424, p = 0.008). Ethnicity-specific meta-analysis demonstrated a relatio

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Young, K. A., M. E. Munroe, J. M. Guthridge, et al. "Screening characteristics for enrichment of individuals at higher risk for transitioning to classified SLE." Lupus 28, no. 5 (2019): 597–606. http://dx.doi.org/10.1177/0961203319834675.

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Objective Further prospective study is needed to elucidate the etiology and natural history of systemic lupus erythematosus development. The clinical complexity of this heterogeneous disease makes study design challenging. Our objective was to ascertain useful screening factors for identifying at-risk individuals for follow-up rheumatologic assessment or inclusion in prospective studies. Methods We attempted to re-contact 3823 subjects with a family history of systemic lupus erythematosus, who did not meet American College of Rheumatology systemic lupus erythematosus classification at a baseli

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Pacheco-Lugo, L., J. Sáenz-García, E. Navarro Quiroz, et al. "Plasma cytokines as potential biomarkers of kidney damage in patients with systemic lupus erythematosus." Lupus 28, no. 1 (2018): 34–43. http://dx.doi.org/10.1177/0961203318812679.

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Background Systemic lupus erythematosus is a heterogeneous chronic inflammatory autoimmune disorder characterized by an exacerbated expression of cytokines and chemokines in different tissues and organs. Renal involvement is a significant contributor to the morbidity and mortality of systemic lupus erythematosus, and its diagnosis is based on renal biopsy, an invasive procedure with a high risk of complications. Therefore, the development of alternative, non-invasive diagnostic tests for kidney disease in patients with systemic lupus erythematosus is a priority. Aim To evaluate the plasma leve

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Shulman, S., R. Shorer, J. Wollman, G. Dotan, and D. Paran. "Retinal nerve fiber layer thickness and neuropsychiatric manifestations in systemic lupus erythematosus." Lupus 26, no. 13 (2017): 1420–25. http://dx.doi.org/10.1177/0961203317703496.

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Background Cognitive impairment is frequent in systemic lupus erythematosus. Atrophy of the corpus callosum and hippocampus have been reported in patients with systemic lupus erythematosus, and diffusion tensor imaging studies have shown impaired white matter integrity, suggesting that white matter damage in systemic lupus erythematosus may underlie the cognitive impairment as well as other neuropsychiatric systemic lupus erythematosus manifestations. Retinal nerve fiber layer thickness, as assessed by optical coherence tomography, has been suggested as a biomarker for white matter damage in n

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Bae, S. C., and Y. H. Lee. "Association between CD40 polymorphisms and systemic lupus erythematosus and correlation between soluble CD40 and CD40 ligand levels in the disease: a meta-analysis." Lupus 28, no. 12 (2019): 1452–59. http://dx.doi.org/10.1177/0961203319878822.

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Objective The aim of this study was to systematically review evidence regarding the association between CD40 polymorphisms and systemic lupus erythematosus and between soluble CD40 (sCD40) and CD40 ligand (sCD40L) levels and systemic lupus erythematosus. Methods We performed a meta-analysis on the association between CD40 rs4810495, rs1883832, and rs376545 polymorphisms and systemic lupus erythematosus risk and sCD40/sCD40L levels in patients with systemic lupus erythematosus and controls. Results Fourteen studies were included. Ethnicity-specific meta-analysis indicated a significant associat

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Vidinikj, Sonja, Dubravka Antova, Maja Bojadzioska, et al. "Severe Complicated Secondary Antiphospholipid Syndrome Conjointly with Systemic Lupus Erythematosus – Case Report." PRILOZI 46, no. 1 (2025): 53–60. https://doi.org/10.2478/prilozi-2025-0006.

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Abstract Antiphospholipid syndrome (APS), is an autoimmune systemic disorder known to manifest with thrombosis in almost all vessels throughout the body, can also be accompanied by pregnancy morbidity, and is persistent with the presence of antiphospholipid antibodies, including lupus anticoagulant antibodies, or relatively high titers of anticardiolipin, or anti-β2Glycoprotein I antibodies. APS can occur alone or in association with other diseases, more commonly systemic lupus erythematous. In patients with both underlying diseases episodes of arthritis, skin changes in the form of livedo ret

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Wenzel, Joerg, Thomas Bieber, Manfred Uerlich, and Thomas Tuting. "Systemische Therapie des kutanen Lupus erythematodes. Systemic treatment of cutaneous lupus erythematosus." Journal der Deutschen Dermatologischen Gesellschaft 1, no. 9 (2003): 694–704. http://dx.doi.org/10.1046/j.1610-0387.2003.03024.x.

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Wang, Liu, Dan Wang, Yuyi Ruan, et al. "Progressive muscle weakness and amyotrophy during pregnancy as the first manifestation of systemic lupus erythematosus: A case report and review of literature." Science Progress 104, no. 4 (2021): 003685042110502. http://dx.doi.org/10.1177/00368504211050276.

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Background: Systemic lupus erythematosus is a common autoimmune disease involving multiple systems. Clinical involvement of the central and peripheral nervous systems is not unusual, but peripheral neuropathy in systemic lupus erythematosus with chronic inflammatory demyelinating polyneuropathy is uncommon. Our study aimed to illustrate the clinical features, diagnosis, and treatment of systemic lupus erythematosus combined with chronic inflammatory demyelinating polyneuropathy, and to aid in the identification of peripheral neuropathy in systemic lupus erythematosus. Methods: This article rep

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Amin, Omed, Arvind Kaul, Toby O. Smith, Franklyn A. Howe, and Nidhi Sofat. "Comparison of structural magnetic resonance imaging findings between neuropsychiatric systemic lupus erythematosus and systemic lupus erythematosus patients: A systematic review and meta-analysis." Rheumatology Practice and Research 2 (January 1, 2017): 205990211666305. http://dx.doi.org/10.1177/2059902116663058.

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Introduction: Neuropsychiatric systemic lupus erythematosus is often clinically challenging to diagnose, treat and monitor. Although brain magnetic resonance imaging is frequently performed before lumbar puncture in neuropsychiatric systemic lupus erythematosus, it is not clear from the literature whether specific brain magnetic resonance imaging findings are associated with distinct clinical features of neuropsychiatric systemic lupus erythematosus. Methods: We conducted a systematic review and meta-analysis on published studies of neuropsychiatric systemic lupus erythematosus including brain

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Hanly, J. G. "Avoiding diagnostic pitfalls in neuropsychiatric lupus: the importance of attribution." Lupus 26, no. 5 (2017): 497–503. http://dx.doi.org/10.1177/0961203317690244.

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Neuropsychiatric events in systemic lupus erythematosus patients may present a diagnostic and therapeutic challenge. Common and heterogeneous, their characterization and attribution to systemic lupus erythematosus and non-systemic lupus erythematosus is important and derived from clinical assessment, selection and interpretation of investigations. A standardized approach to assigning attribution has been used in recent studies. The current therapies are largely empiric, based upon known disease mechanisms and treatment of other serious organ disease in systemic lupus erythematosus. Further ins

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Rekik, Mariem, Khadija Sellami, Massara Baklouti, Emna Bahloul, and Hamida Turki. "Oral involvement in lupus erythematosus: A report of three cases." Our Dermatology Online 13, no. 4 (2022): 467–68. http://dx.doi.org/10.7241/ourd.20224.31.

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Sir, Lupus erythematosus (LE) is an autoimmune disease that may rarely affect the oral mucosa. This mucosal damage may be mistaken for lichen planus. Herein, we report three cases of oral lupus. Observation 1: A 41-year-old female, with a seven-year history of systemic LE (SLE) treated with hydroxychloroquine, presented for recent food discomfort. An examination of the oral mucosa found an erythematous plaque on the palate (Fig. 1) and whitish macules on the cheek mucosa. A palatal biopsy was in favor of lupus.

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Kwon, Oh Chan, Yong-Gil Kim, Jung Hwan Park, and Min-Chan Park. "Seroconversion to antinuclear antibody negativity and its association with disease flare in patients with systemic lupus erythematosus." Lupus 29, no. 7 (2020): 697–704. http://dx.doi.org/10.1177/0961203320917748.

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Objective To evaluate the rate of seroconversion to antinuclear-antibody negativity in patients with systemic lupus erythematosus and its association with subsequent systemic lupus erythematosus flare risk. Methods Medical records of patients with systemic lupus erythematosus with positive antinuclear antibodies (titer ≥1 : 40) at diagnosis and at least one repeat antinuclear antibody test were reviewed. We determined the frequency of seroconversion to antinuclear antibody negativity among these patients and investigated whether seroconversion to antinuclear antibody negativity was associated

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Agmon-Levin, N., M. Blank, Z. Paz, and Y. Shoenfeld. "Molecular mimicry in systemic lupus erythematosus." Lupus 18, no. 13 (2009): 1181–85. http://dx.doi.org/10.1177/0961203309346653.

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Systemic lupus erythematosus is a multi-systemic autoimmune disease distinguished by the presence of various autoantibodies. Like most autoimmune diseases, systemic lupus erythematosus is believed to be induced by a combination of genetic, immunologic, and environmental factors, mainly infectious agents. Molecular mimicry between an infectious antigen and self-components is implicated as a pivotal mechanism by which autoimmune diseases such as systemic lupus erythematosus are triggered. Here we review the current evidence of molecular mimicry between different infectious agents and systemic lu

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Melgarejo Paniagua, Patricia Alexandra, Amado Emilio Denis Doldán, Marta Inés Ferreira Gaona, and Clarisse Virginia Díaz Reissner. "Complicaciones en pacientes con lupus eritematoso sistémico." DEL NACIONAL 7, no. 1 (2015): 28–31. http://dx.doi.org/10.18004/rdn2015.0007.01.028-031.

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Guilherme, Andrea Regina Cavazotto, and Marta Maria Círchia Pinto Luppi. "Diagnóstico de lúpus eritematoso discóide em cão." Pubvet 18, no. 08 (2024): e1645. http://dx.doi.org/10.31533/pubvet.v18n08e1645.

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In veterinary medicine one of the biggest challenges of the small clinic are the rare autoimmune diseases, especially on dermatology care, due to their complexity and lack of response to conventional skin treatments. Lupus erythematosus is one of these diseases that, in addition to affecting humans, is often diagnosed in dogs, and among its various classifications are systemic lupus erythematosus and discoid lupus erythematosus, which some authors believe to be a benign variation of the systemic lupus. The present study aims to report the case of a 9-year-old mixed-breed dog, rescued and kept

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Di Matteo, A., M. Isidori, D. Corradini, et al. "Ultrasound in the assessment of musculoskeletal involvement in systemic lupus erythematosus: state of the art and perspectives." Lupus 28, no. 5 (2019): 583–90. http://dx.doi.org/10.1177/0961203319834671.

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Musculoskeletal manifestations are extremely common in patients with systemic lupus erythematosus. Transient and migratory arthralgia is frequently reported even without clinical signs of joint or tendon inflammation. In less than 15% of patients, joints may be more severely affected by deforming (Jaccoud's arthropathy) and/or erosive arthropathy (Rhupus syndrome). In recent years, ultrasound has emerged as a promising imaging technique for the assessment of musculoskeletal involvement in systemic lupus erythematosus, having demonstrated the ability to detect inflammation and structural damage

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Clark, K. E. N., C. N. Clark, and A. Rahman. "A critical analysis of the tools to evaluate neuropsychiatric lupus." Lupus 26, no. 5 (2017): 504–9. http://dx.doi.org/10.1177/0961203317690242.

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Neuropsychiatric symptoms occur commonly in patients with systemic lupus erythematosus, but they are not always due to active disease. It is crucial to identify cases that are due to active systemic lupus erythematosus so that appropriate treatment can be instituted. There is no single serological or imaging test that distinguishes active neuropsychiatric systemic lupus erythematosus from neuropsychiatric manifestations caused by other factors such as infection. Most patients with neuropsychiatric systemic lupus erythematosus have generalised features of disease activity. Raised anti-dsDNA and

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Koch, K., and M. Tikly. "Spectrum of cutaneous lupus erythematosus in South Africans with systemic lupus erythematosus." Lupus 28, no. 8 (2019): 1021–26. http://dx.doi.org/10.1177/0961203319856091.

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Background Cutaneous involvement is very common in systemic lupus erythematosus. We describe the prevalence and spectrum of lupus-specific (cutaneous lupus erythematosus) and non-specific cutaneous features amongst mostly black South Africans with systemic lupus erythematosus. Patients and methods A retrospective record review of 298 South Africans (262 blacks and 36 non-blacks) with systemic lupus erythematosus was carried out. Cutaneous features were classified according to the Gilliam and Sontheimer classification of cutaneous lupus. Results Most (81.5%) patients were black African females.

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