Relevant bibliographies by topics / Systemic thrombolysis

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Systemic thrombolysis'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Systemic thrombolysis"

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Bajka, Balázs, Edvin Benedek, Alexandra Stănescu, Emese Rapolti, Monica Chițu, and István Kovács. "Treatment Difficulties in High Risk Pulmonary Embolism. A Case Report." Journal Of Cardiovascular Emergencies 2, no. 1 (2016): 37–42. http://dx.doi.org/10.1515/jce-2016-0007.

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Abstract Pulmonary embolism (PE) remains a common and potentially life-threatening cardiovascular emergency. Systemic thrombolysis with intravenous infusion of a thrombolytic agent is generally recommended for treatment of high risk PE. However, this method has known limitations in the presence of high bleeding risk. Catheter-directed thrombolysis has the potential to achieve the same benefits as systemic thrombolysis, with a lower risk of haemorrhage. The case presented is of a 67-year-old male patient with a high risk of pulmonary embolism and contraindications for systemic thrombolysis, in
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Terrin, Alberto, Giulia Toldo, Mario Ermani, Federico Mainardi, and Ferdinando Maggioni. "When migraine mimics stroke: A systematic review." Cephalalgia 38, no. 14 (2018): 2068–78. http://dx.doi.org/10.1177/0333102418767999.

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Background Migraine with aura may mimic an acute ischemic stroke, so that an improper administration of thrombolytic treatment can expose migrainous patients to severe adverse effects. Methods This systematic review quantifies the relevance of migraine with aura among stroke mimics, checking for thrombolysis’ safety in these patients. We reviewed the literature after 1995, distinguishing from studies dealing with stroke mimics treated with systemic thrombolysis and those who were not treated with systemic thrombolysis. Results Migraine with aura is responsible for 1.79% (CI 95% 0.82–3.79%) of
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Knoll, Thomas, Christian Weimar, Roman L. Haberl, et al. "Systemic Thrombolysis Data from the German Stroke Database." Stroke 32, suppl_1 (2001): 337. http://dx.doi.org/10.1161/str.32.suppl_1.337-b.

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118 Objectives: To present data on systemic thrombolysis for acute ischemic stroke from a cooperative database of 23 german hospitals. Methods: All admitted stroke patients in the participating centers were prospectively recruited into a 599-item database including a telephone follow-up 3 months after stroke. Findings: From 01/1998 until 11/1999, 5279 patients with acute ischemic stroke were included in the database, 205 (3.9%) had systemic thrombolysis with 0.9mg/kg rt-PA (alteplase). Three hospitals did not perform thrombolysis (range of thrombolysis rate 0–11.3%). The median age of patients
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Cheema, Ali Akhtar, Robert H. Mallinson, and Nicola Trepte. "Advances in Deep Vein Thrombosis Management with Thrombolysis." Acute Medicine Journal 8, no. 2 (2009): 63–69. http://dx.doi.org/10.52964/amja.0234.

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Lower extremity deep vein thrombosis (DVT) is a common disease associated with serious short term and long term complications. Its conventional treatment has been anticoagulation. Thrombolytic treatment has been used for DVT for over 40 years. More recently catheter directed thrombolysis has taken over systemic thrombolysis. This technique is useful to prevent post thrombotic syndrome (PTS) after DVT. In this review article we present a case of DVT thrombolysis in our hospital, look at the pathophysiology of PTS, the mechanism of thrombolysis and the current status of thrombolysis in DVT.
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Latfullin, I. A., A. V. Bondarev, A. A. Podolskaya, and E. I. Aglullina. "Thrombolytic therapy of the acute myocardial infarction by cabicinase." Kazan medical journal 79, no. 4 (1998): 251–54. http://dx.doi.org/10.17816/kazmj64386.

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The necessity to perform the systemic thrombolysis to patients with acute myocardial infarction is emphasized. The most effective and save thrombolytic agent is cabicanase. The recommendations for practical physicians are worthy of notice. The control of blood coagulability velocity and hemorrhage lingering is obligatory in the performance of thrombolysis; if it is possible, thrombelastograms are to be studied. It is essential to know well the contradictions to thrombolysis.
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Domashenko, Maksim A., Marina Yu Maksimova, and Marine M. Tanashyan. "Intravenous thrombolysis in ischemic stroke: clinical predictors of efficacy and safety." Annals of Clinical and Experimental Neurology 13, no. 1 (2019): 5–14. https://doi.org/10.25692/acen.2019.1.1.

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Introduction. Systemic thrombolysis with recombinant tissue plasminogen activator is the gold standard of reperfusion therapy, having the maximum level of evidence in European and North American guidelines for the treatment of patients with acute ischemic stroke (IS).Objective: to determine factors of individual efficacy and safety of systemic thrombolysis in patients with IS aiming to establish personalized approach to its optimization.Materials and methods. The study included 396 patients with IS, of whom 196 patients underwent systemic thrombolysis with recombinant tissue plasminogen activa
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Geraets, Douglas R., James D. Hoehns, Timothy G. Burke, and Maleah Grover‐McKay. "Thrombolytic‐Associated Cholesterol Emboli Syndrome: Case Report and Literature Review." Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 15, no. 4 (1995): 441–50. http://dx.doi.org/10.1002/j.1875-9114.1995.tb04380.x.

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Thrombolytics can cause cholesterol embolization syndrome (CES). This adverse effect has received less attention than other risks of thrombolytic therapy, such as systemic bleeding and hemorrhage, with only sporadic reports of CES in the literature. Risk factors have not been consistently identified and emphasized; therefore, occurrence of CES after thrombolysis remains difficult to predict, it results in substantial morbidity and mortality, and it lacks effective pharmacologic treatment. Heightened awareness of the disorder can aid in its correct identification and reporting.
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Barca-Hernando, María, and Luis Jara-Palomares. "When should we involve interventional radiology in the management of acute pulmonary embolism?" Breathe 19, no. 3 (2023): 230085. http://dx.doi.org/10.1183/20734735.0085-2023.

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Pulmonary embolism (PE) is a common disease associated with high morbidity and mortality. Currently, guidelines recommend systemic thrombolysis in patients with haemodynamic instability (high-risk PE) or patients with intermediate–high-risk PE with haemodynamic deterioration. Nevertheless, more than half of high-risk PE patients do not receive systemic thrombolysis due to a perceived increased risk of bleeding. In these cases, percutaneous catheter-directed therapy (CDT) or surgical embolectomy should be considered. CDT has emerged and appears to be an effective alternative in treating PE, wit
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Saraswathi, T., T. Gopinathan, Balakumaran Balakumaran, and Yuvaraj Y. "Obstructive Shock Pulmonary Embolism: Catheter Directed Thrombolysis." Journal of Clinical Cases and Reports 6, S14 (2023): 254–56. http://dx.doi.org/10.46619/joccr.2023.6-s14.1079.

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Venous thromboembolism is one of the most frequently encountered condition for which patients need intensive care admission often. Most of the time patients presents with shock and hemodynamic instability if it is massive pulmonary embolism. Incidence of Vte is comparable to western population in India, studies conducted by Ayyapan et all say it around 20/10,000 admission. Studies showed higher mortality of around 50% in high risk (massive) and mortality of around 14% in intermediate risk (sub-massive) PE which necessitating more aggressive approach in high-risk groups. Rapid administration of
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Chiasakul, Thita, and Kenneth A. Bauer. "Thrombolytic therapy in acute venous thromboembolism." Hematology 2020, no. 1 (2020): 612–18. http://dx.doi.org/10.1182/hematology.2020000148.

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Abstract Although anticoagulation remains the mainstay of treatment of acute venous thromboembolism (VTE), the use of thrombolytic agents or thrombectomy is required to immediately restore blood flow to thrombosed vessels. Nevertheless, systemic thrombolysis has not clearly been shown to improve outcomes in patients with large clot burdens in the lung or legs as compared with anticoagulation alone; this is in part due to the occurrence of intracranial hemorrhage in a small percentage of patients to whom therapeutic doses of a thrombolytic drug are administered. Algorithms have been developed t
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Dissertations / Theses on the topic "Systemic thrombolysis"

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Seners, Pierre. "Recanalisation artérielle précoce après thrombolyse intraveineuse d’un accident ischémique cérébral avec occlusion artérielle proximale : incidence, prédiction et physiopathologie Indicidence and predictors of early recanalization following IV thrombolysis. A systematic review and meta-analysis Post-thrombolysis recanalization in stroke referrals for thrombectomy: Incidence, predictors and prediction scores Relationships between brain perfusion and early recanalization after intravenous thrombolysis for acute stroke with large vessel occlusion Better collaterals are independently associated with post-thrombolysis recanalization before thrombectomy Thrombus length predicts lack of post-thrombolysis early recanalization in minor stroke with large vessel occlusion Early recanalization in tenecteplase vs. alteplase-treated drip-and-ship patients referred for thrombectomy." Thesis, Sorbonne Paris Cité, 2018. http://www.theses.fr/2018USPCB222.

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À la phase aigüe de l’accident ischémique cérébral (AIC) avec occlusion artérielle proximale, la cible thérapeutique principale est l’obtention d’une recanalisation artérielle la plus rapide possible. L’utilisation combinée de la thrombolyse intraveineuse (TIV) par alteplase et de la thrombectomie mécanique (TM), dénommée « bridging therapy » et recommandée depuis 2015, est actuellement remise en question car i) en cas de faible probabilité de recanalisation précoce (RP) post-TIV, celle-ci pourrait être non seulement inutile, mais aussi délétère ; et ii) inversement, si la probabilité de RP es
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Matúšová, Veronika. "Kvalita života pacienta po systémové trombolýze." Master's thesis, 2012. http://www.nusl.cz/ntk/nusl-305486.

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Diploma thesis "Quality of life of patients after systemic thrombolysis" is dealing with the impact of systemic thrombolysis to the quality of life of patients affected by the ischemic stroke (IS) and treated with intravenous administration of thrombolytics. The goal is to objectively assess quality of life resulting from health improvement after systemic thrombolysis. The work consists of theoretical and practical part. The theoretical part describes ischemic stroke, its etiology, symptoms and treatment options. The second chapter is devoted to the practical part of the term "quality of life"
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Books on the topic "Systemic thrombolysis"

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A, Boland, National Co-ordinating Centre for HTA (Great Britain), and Health Technology Assessment Programme, eds. Early thrombolysis for the treatment of acute myocardial infarction: A systematic review and economic evaluation. Core Research on behalf of the NCCHTA, 2003.

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Peter, Sandercock, National Co-ordinating Centre for HTA (Great Britain), and Health Technology Assessment Programme, eds. A Systematic review of the effectiveness, cost-effectiveness and barriers to implementation of thrombolytic and neuroprotective therapy for acute ischaemic stroke in the NHS. NCCHTA, 2002.

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Valentin, Fuster, and Verstraete M, eds. Thrombosis in cardiovascular disorders. Saunders, 1992.

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Chong, Ji Y., and Michael P. Lerario. Progressive Quadriplegia. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190495541.003.0005.

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Spinal cord ischemia most often presents as an anterior spinal artery syndrome and involves watershed regions of the spinal cord. The clinical presentation and etiologies can be heterogeneous, but cord infarcts are typically the result of aortic surgeries, systemic hypotension, vertebral artery and aortic dissections, embolus, or vascular malformations. Given that it is a rare entity, involving symptoms that can progress over minutes to hours, a diagnosis is often delayed until after conventional windows for revascularization, including thrombolysis, have passed. Magnetic resonance imaging (MR
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Moore, Laurel E. Acute Stroke. Edited by Matthew D. McEvoy and Cory M. Furse. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190226459.003.0063.

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Stroke is the leading cause of disability in the United States, and in terms of mortality is second only to ischemic heart disease worldwide. Medical management for acute ischemic stroke (AIS) was limited to supportive care until 1995, when the National Institute of Neurological Disorders and Stroke (NINDS) trial demonstrated improved outcomes with systemic thrombolysis for AIS. Since December 2014, four major articles have been published in support of endovascular intervention for AIS, making this a central focus of this chapter. Other related topics for this chapter include the timing of ele
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Koczo, Agnes, Reshad Mahmud, and Belinda Rivera-Lebron. Pulmonary Embolism (DRAFT). Edited by Raghavan Murugan and Joseph M. Darby. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190612474.003.0020.

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This chapter examines the diagnosis, risk stratification, and breadth of treatment options for pulmonary embolism (PE). It reviews the decision pathways based on degree of clinical suspicion of PE and assessing pre-test probability using the Geneva and Wells’ Score. It also reviews the Pulmonary Embolism Rule-out Criteria (PERC) and D-dimer with high negative predictive values. Imaging and cardiac biomarkers, which allow classification and risk stratification of PE, are discussed in how they guide management. Options for parenteral anticoagulation including bridging to novel oral anticoagulant
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Torbicki, Adam, Marcin Kurzyna, and Stavros Konstantinides. Pulmonary embolism. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0066.

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Pulmonary embolism is usually a consequence of deep vein thrombosis, and together the two conditions are known as venous thromboembolism. Non-thromboembolic causes of pulmonary embolism are rare. Pulmonary thromboembolism is a potentially life-threatening disease, if left untreated. This is due to a natural tendency towards early recurrence of pulmonary emboli which may lead to fatal right ventricular failure. In more severe cases, secondary right ventricular failure may result from myocardial ischaemia and injury caused by systemic hypotension and adrenergic overstimulation. Clinical presenta
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Torbicki, Adam, Marcin Kurzyna, and Stavros Konstantinides. Pulmonary embolism. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199687039.003.0066_update_001.

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Pulmonary embolism is usually a consequence of deep vein thrombosis, and together the two conditions are known as venous thromboembolism. Non-thromboembolic causes of pulmonary embolism are rare. Pulmonary thromboembolism is a potentially life-threatening disease, if left untreated. This is due to a natural tendency towards early recurrence of pulmonary emboli which may lead to fatal right ventricular failure. In more severe cases, secondary right ventricular failure may result from myocardial ischaemia and injury caused by systemic hypotension and adrenergic overstimulation. Clinical presenta
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Torbicki, Adam, Marcin Kurzyna, and Stavros Konstantinides. Pulmonary embolism. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199687039.003.0066_update_002.

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Pulmonary embolism is usually a consequence of deep vein thrombosis, and together the two conditions are known as venous thromboembolism. Non-thromboembolic causes of pulmonary embolism are rare. Pulmonary thromboembolism is a potentially life-threatening disease, if left untreated. This is due to a natural tendency towards early recurrence of pulmonary emboli which may lead to fatal right ventricular failure. In more severe cases, secondary right ventricular failure may result from myocardial ischaemia and injury caused by systemic hypotension and adrenergic overstimulation. Clinical presenta
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Torbicki, Adam, Marcin Kurzyna, and Stavros Konstantinides. Pulmonary embolism. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199687039.003.0066_update_003.

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Pulmonary embolism is usually a consequence of deep vein thrombosis, and together the two conditions are known as venous thromboembolism. Non-thromboembolic causes of pulmonary embolism are rare. Pulmonary thromboembolism is a potentially life-threatening disease, if left untreated. This is due to a natural tendency towards early recurrence of pulmonary emboli which may lead to fatal right ventricular failure. In more severe cases, secondary right ventricular failure may result from myocardial ischaemia and injury caused by systemic hypotension and adrenergic overstimulation. Clinical presenta
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Book chapters on the topic "Systemic thrombolysis"

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Stewart, Lauren K., and Jeffrey A. Kline. "Indications for Systemic Thrombolysis Over Anticoagulation." In Pulmonary Embolism. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-51736-6_6.

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AlMatter, Muhammad, Hubert Kimmig, and Christian Palm. "Embolic Occlusion of the Anterior Cerebral Artery A2 Segment Treated with Concomitant Systemic Thrombolysis and Local Intra-Arterial Thrombolysis via the Contralateral Side." In The Ischemic Stroke Casebook. Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-47201-5_42.

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AlMatter, Muhammad, Hubert Kimmig, and Christian Palm. "Embolic Occlusion of the Anterior Cerebral Artery A2 Segment Treated with Concomitant Systemic Thrombolysis and Local Intra-Arterial Thrombolysis via the Contralateral Side." In The Ischemic Stroke Casebook. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-030-85411-9_42-1.

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Martin, M. "Pharmacological Thrombolysis - Systematic Therapy." In Radiology of Peripheral Vascular Diseases. Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-56956-2_22.

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Küppers-Tiedt, Lea, Anatol Manaenko, Dominik Michalski, et al. "Combined Systemic Thrombolysis with Alteplase and Early Hyperbaric Oxygen Therapy in Experimental Embolic Stroke in Rats: Relationship to Functional Outcome and Reduction of Structural Damage." In Intracerebral Hemorrhage Research. Springer Vienna, 2011. http://dx.doi.org/10.1007/978-3-7091-0693-8_28.

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Robbins, Blake, Komal Pandya, and George A. Davis. "Systemic Thrombolytic Therapy for Acute Pulmonary Embolism." In PERT Consortium Handbook of Pulmonary Embolism. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-030-70904-4_8-1.

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Verstraete, M. "Systemic Versus Intracoronary Thrombolytic Treatment in Acute Myocardial Infarction." In Update in Intensive Care and Emergency Medicine. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-70309-6_48.

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Morris, Pearse. "Thrombolysis and Treatment of Acute Stroke." In Interventional and Endovascular Therapy of the Nervous System. Springer New York, 2002. http://dx.doi.org/10.1007/978-1-4757-3673-1_13.

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Cai, Jiayi, and Jialiang Cai. "Design Innovation and Application Practice Based on Automatic Thrombolysis After Ischemic Stroke." In Web Information Systems and Applications. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-6222-8_49.

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Haines, Daniel, and Joel Grigsby. "Pulmonary Embolism and Postoperative Care." In Cardiothoracic Critical Care. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780190082482.003.0006.

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This chapter assesses pulmonary embolism (PE), which is an obstruction of the pulmonary circulation by an occlusive material. The material may be thrombus, air, tumor, or fat. PE are classified as acute, subacute, or chronic; but they can be further classified into massive and submassive. Submassive PE is defined as an acute PE without systemic hypotension but with either right ventricular dysfunction or myocardial necrosis, while massive PE is defined as an acute PE with sustained shock. There are several strategies for treating PE depending on the stability of the patient and the location of
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Conference papers on the topic "Systemic thrombolysis"

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Mazhar, R., and J. Gisel. "Use of Catheter-Directed Thrombolytic Therapy for Ongoing Shock After Systemic Thrombolysis for Massive Pulmonary Embolism." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a3448.

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Simeone, S., and E. Nadler. "High Risk Pulmonary Embolism Complicated by Systemic Thrombosis Requiring Systemic Thrombolysis and Multiple Endovascular Procedures." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2868.

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Seifried, E., D. C. Rijken, B. Hoeqee, P. TansiAiell, C. Kluft, and W. Nieuwenhuizen. "FIBRIN DEGRADATION PRODUCTS (FbDP) IN HEALTHY VOLUNTEERS AFTER INFUSION OF RECOMBINANT TISSUE-TYPE PLASMINOGEN ACTIVATOR(rt-PA)." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643654.

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During thrombolytic therapy of myocardial infarction (MI) with urokinase or streptokinase (SK), levels of fibrin(ogen) degradation products in serum are often dramatically elevated as a result of a combination of systemic fibrinogenolysis and local thrombolysis. Others have measured increased levels of D-dimer in serum of MI patients after SK therapy and postulated that thrombolysis could be monitored during SK therapy by measuring D-dimer levels. In the present study rt-PA was infused into healthy volunteers to analyse if elevated FbDP levels in MI patients really reflect coronary thrombolysi
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Kwok, B., A. Katz, F. Dikengil, et al. "Time to Systemic Thrombolysis in Confirmed Massive Pulmonary Embolism in a Single Center." In American Thoracic Society 2021 International Conference, May 14-19, 2021 - San Diego, CA. American Thoracic Society, 2021. http://dx.doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a3728.

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Shainoff, John R., Youko Hishikawa-Itoh, Fred M. Lucas, Robert Graor, and Bernadine Healy. "IMMUNOELECTROPHORETIC CHARACTERIZATION OF SYSTEMIC FIBRINOGEN DURING THROMBOLYSIS OF PERIPHERAL ARTERIAL EMBOLI WITH tPA." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643889.

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Prompted by uncertainties over the possibility of ex-vivo alterations of fibrinogen in plasma samples from patients receiving thrombolytic agents, we sought to 1) use sodium dodecyl sulfate (SDS) and mild acidification to pH 5 as a general means for inhibiting post-sampling proteolysis, and 2) assess the chemical state of fibrinogen by immuno-electrophoretically profiling the molecular weight distribution of the fibrinogen-related antigens in the sample. Blood samples taken into EDTA and PPACK were immediately centrifuged, and plasma diluted 5X in 2% SDS and 0.04% monochloroacetic acid. Such s
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Scott, J., R. Vender, S. Pettigrew, et al. "Veno-Arterial Extracorporeal Membrane Oxygenation for Pulmonary Embolism After Cardiac Arrest and Systemic Thrombolysis: A Systematic Review." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1993.

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Momier, P., U. Sigwart, F. Bachmnn, C. Ferret, and L. Kapperiberger. "SYSTEMIC THRCMBOLYSIS WITHIN THE FIRST 3 HOURS OF ACUTE CORONARY THROMBOSIS : APSAC VS STREPTOKINASE : A RAMDCMIZED STUDY." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642995.

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Intravenous administration of thrombolytic agents in acute myocardial infarction may be preferable to intracoronary thrombolysis for practiced, reasons and to reduce time to reperfusion. As compared to the streptokinase infusion, the bolus injection of APSAC may be even more rational. We have therefore compared the effects of one intravenous bolus injection of APSAC (30 units in 5 min) to an intravenous injection of streptokinase (1.500.000 units in 60 min) within the first 3 hours (mean 141 min for APSAC and 135 min for streptokinase) after the onset of symptoms associated with acute myocardi
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Hirschberg, M., A. Manoutchei, B. Klemens, and B. Hofferberth. "CEREBRAL THROMBOLYSIS WITH INTRAVENOUSLY ADMINISTERED RECOMBINANT LOW- MOLECULAR-WEIGHT-UROKINASE AND RECOMBINANT PRO-UROKINASE IN A DOG MODEL." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643571.

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There is increasing evidence that recombinant prourokinase (rec-pro-UK) is a proenzyme which in vivo systems may induce activation of the fibrinolytic system with a better thrombus selectivity than that obtained with active urokinase.In order to study the effects of rec-pro-UK and low-molecular-weight-urokinase (LMW-UK) on acute stroke, a thrombus was induced in the middle cerebral artery (MCA) of anesthetized mongrel dogs (n=12). Occlusion of the vessel was confirmed by angiography. Following a 1 hour period of MCA occlusion, in six animals LMW-UK was administered intravenously at a dose of 4
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Rijal, S. S., A. Sullivan, and D. Young. "A Rare Case of Systemic Thrombolysis Failure in Massive Pulmonary Embolism Requiring Catheter-directed Intervention." In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a5523.

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Pettigrew, S., A. Chung, K. Alexander, et al. "Comparison of Events Across Bleeding Scales in Patients Who Underwent CDT and Systemic Thrombolysis- A Single Center Retrospective Review." In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2008.

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Reports on the topic "Systemic thrombolysis"

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Zaslavsky, Kirill, Jim Shenchu Xie, Hargun Kaur, Yasmin Motekalem, Yuri Chaban, and Edward Margolin. Efficacy of intra-arterial or intravenous thrombolytic therapy versus conservative standard therapy for central retinal artery occlusion: an individual patient data meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.5.0095.

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Review question / Objective: The primary aim of this systematic review and meta-analysis is to compare the efficacy of intra-arterial thrombolysis (IAT), intravenous thrombolysis (IVT), and conservative standard therapies (CST) for central retinal artery occlusion (CRAO) to better inform clinical practice. To this end, the proposed study will address the following question: which of the following interventions is the most effective at reducing severe vision loss in patients with CRAO: IAT, IVT, or CST? Secondary aims include determining an optimal time window for IAT and IVT in CRAO; comparing
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Bao, QiangJi, XinTing Wu, JinCai Yang, et al. Intravenous thrombolysis in acute ischemic stroke patients with prestroke disability：A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.8.0098.

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Pan, Xingbang, Xiangfei Chen, Jingtao Guo, Donglei Luo, and Jiang Zhou. A systematic review and meta-analysis of the predictors to the successful thrombolysis treatment in STsegment elevated infarction. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2020. http://dx.doi.org/10.37766/inplasy2020.8.0049.

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Wu, Xin, Yi Ge, Tao Xue, and Zhong Wang. Mechanical thrombectomy with or without intravenous thrombolysis in patients with acute ischemic stroke: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.3.0094.

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Guo, Changwei, Kaesmacher Johannes, Mujanovic Adnan, et al. Intra-arterial Thrombolysis Following Successful Thrombectomy in Patients with Acute Large Vessel Occlusion: A systematic review and meta-analysis of Randomized Control Trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2025. https://doi.org/10.37766/inplasy2025.1.0043.

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Gao, Shanshan, Dongdong Yang, Hengni Yan, Yuxuan Chao, and Yu Fang. Efficacy and safety analysis of Chinese herb injections promoting blood circulation combined with intravenous thrombolysis with alteplase in hyperacute cerebral infarction patients：a systematic review and Meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2020. http://dx.doi.org/10.37766/inplasy2020.6.0093.

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