Log in

Relevant bibliographies by topics / Systems pharmacology / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Systems pharmacology.

Dissertations / Theses on the topic 'Systems pharmacology'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 dissertations / theses for your research on the topic 'Systems pharmacology.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Duran-Frigola, Miquel 1985. "Blending biology and chemistry to enable systems pharmacology." Doctoral thesis, Universitat Pompeu Fabra, 2016. http://hdl.handle.net/10803/459111.

Full text

Abstract:

The avalanche of data that followed the sequencing of the human genome has revealed an overwhelming biological complexity. No simple molecular explanation exists for most of the diseases and, in consequence, simple therapies have low probability of success. The emerging field of systems pharmacology seeks drugs of broad impact on molecular networks. To achieve so, it is necessary to integrate heterogeneous data, at different levels of complexity, and find correlations between them. This translational exercise is, perhaps, the major concern of current biomedical research. In this Thesis we und

APA, Harvard, Vancouver, ISO, and other styles

2

Kuenzi, Brent M. "Off-Target Based Drug Repurposing Using Systems Pharmacology." Scholar Commons, 2018. https://scholarcommons.usf.edu/etd/7689.

Full text

Abstract:

The goal of this study was to identify novel drug repurposing opportunities in cancer by utilizing the off-target profiles of clinically relevant kinase inhibitors. This was based on the observation that the global target profiles of compounds are largely ignored and that many compounds have activity that cannot be explained by their cognate target alone. Additionally, by utilizing clinically relevant compounds, any results would hold a high potential for eventual clinical implementation. We utilized a systems pharmacology approach utilizing cell viability-based drug screening to identify comp

APA, Harvard, Vancouver, ISO, and other styles

3

Knight, Anthony. "A systems pharmacology approach to the adenosine A1 receptor." Thesis, University of Warwick, 2015. http://wrap.warwick.ac.uk/75201/.

Full text

Abstract:

The majority of drugs are prescribed on the premise that their desired and undesired effects are well characterised. However, the mechanisms underlying these effects can be elusive and are of interest to the pharmaceutical industry in terms of rational drug design. G protein-coupled receptors are a significant class of drug target that are capable of influencing multiple signalling processes, and downstream effects, simultaneously through a variety of effectors, such as G proteins or –β-arrestins. The effector activated by a given receptor is often a function of the ligand. This is termed func

APA, Harvard, Vancouver, ISO, and other styles

4

Knight-Schrijver, Vincent. "Towards systems pharmacology models of druggable targets and disease mechanisms." Thesis, University of Cambridge, 2019. https://www.repository.cam.ac.uk/handle/1810/289731.

Full text

Abstract:

The development of essential medicines is being slowed by a lack of efficiency in drug development as ninety per cent of drugs fail at some stage during clinical evaluation. This attrition in drug development is seen not because of a reduction in pharmaceutical research expenditure nor is it caused by a declining understanding of biology, if anything, these are both increasing. Instead, drugs are failing because we are unable to effectively predict how they will work before they are given to patients. This is due to limitations of the current methods used to evaluate a drug's toxicity and effi

APA, Harvard, Vancouver, ISO, and other styles

5

Shahid, Mohammad [Verfasser]. "Integrative Systems Approaches Towards Brain Pharmacology and Polypharmacology / Mohammad Shahid." Bonn : Universitäts- und Landesbibliothek Bonn, 2014. http://d-nb.info/1051028175/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Kelly, R. A. "Biochemical thermodynamic modelling of cellular bioenergetics : a quantitative systems pharmacology approach." Thesis, Liverpool John Moores University, 2018. http://researchonline.ljmu.ac.uk/7754/.

Full text

Abstract:

In this thesis, thermodynamic-based mathematical modelling is combined with experimental in vitro extracellular flux analysis in order to assess drug redox cycling and cellular bioenergetics. It is widely accepted that pharmacological activity of certain classes of drugs (e.g. anticancer, antimalarial) is related to their ability to accept one or two electrons. However, pharmacological activity via redox cycling is an understated mechanism of toxicity associated with many classes of drugs. In particular, oxidative stress as a result of redox cycling plays a pivotal role in the cause of cardiac

APA, Harvard, Vancouver, ISO, and other styles

7

Stockmeier, Craig A., and Gregory A. Ordway. "Interactions of Norepinephrine With Other Neurotransmitter Systems: Anatomical Basis and Pharmacology." Digital Commons @ East Tennessee State University, 2007. https://dc.etsu.edu/etsu-works/8614.

Full text

Abstract:

Introduction Norepinephrine-containing neurons clustered within the locus coeruleus (LC) provide most of the norepinephrine present within the central nervous system. These cells have tonic pacemaker activity and this activity is regulated by a variety of neurotransmitter inputs. The focus of this review is primarily on classical, non-neuropeptide, neurotransmitter input to the LC and the reciprocal projections of noradrenergic neurons to those classical neurotransmitter systems. Input to the LC from serotonin-, dopamine-, γ-aminobutyric acid (GABA)-, glutamate-, and acetylcholine-containing n

APA, Harvard, Vancouver, ISO, and other styles

8

Ali, Habib. "Engineering liposomal systems to develop solubility enhancing technology." Thesis, Aston University, 2008. http://publications.aston.ac.uk/15264/.

Full text

Abstract:

This research primarily focused on identifying the formulation parameters which control the efficacy of liposomes as delivery systems to enhance the delivery of poorly soluble drugs. Preliminary studies focused on the drug loading of ibuprofen within vesicle systems. Initially both liposomal and niosomal formulations were screened for their drug-loading capacity: liposomal systems were shown to offer significantly higher ibuprofen loading and thereafter lipid based systems were further investigated. Given the key role cholesterol is known to play within the stability of bilayer vesicles. the o

APA, Harvard, Vancouver, ISO, and other styles

9

Carruthers, Alan Mark. "Metabotropic glutamate receptor pharmacology and signalling in model and neuronal cell systems." Thesis, University of Leicester, 1997. http://hdl.handle.net/2381/29926.

Full text

Abstract:

In rat cerebellar granule cells measurement of phosphoinositide turnover and cAMP formation revealed that mGluR effects on these two parameters were developmentally regulated. Inhibitory effects on cAMP formation and phosphoinositide turnover increased in parallel followed by a decline to lower values coinciding with an increased sensitivity of the neurons to NMDA and L-glutamate excitotoxicity. Phosphoinositide responses mediated by group I mGluRs present on cerebellar granule neurons (thought previously to be predominantly mediated by mGluR1 in these cells) were insensitive to pertussis toxi

APA, Harvard, Vancouver, ISO, and other styles

10

Jenner, Simon, and Dennis Amphan. "Linking Systems Models of Pharmacology with Behavioural Models of Adherence : A Feasibility Study." Thesis, KTH, Medicinteknik och hälsosystem, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-278166.

Full text

Abstract:

Pharmacokinetic (PK)- and pharmacodynamic (PD) modeling are useful tools whenassessing treatment effect. A patient’s adherence can potentially be rate-limiting, since it isthe first process in a chain of processes that determines treatment effect. Therefore agreater system taking into consideration PKPD as well as adherence models couldpotentially unlock a greater system understanding. This study focuses on investigating thefeasibility of combining models concerning adherence, PK and PD. An extensive mapping of previously made work on the topics of PKPD model developmentand adherence models co

APA, Harvard, Vancouver, ISO, and other styles

11

Clarke, Amanda Sue. "Studies of interparticulate adhesion and cohesion in dry powder inhalation systems." Thesis, De Montfort University, 1997. http://hdl.handle.net/2086/4815.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Abodinar, Atiga Emhemed. "Construction of potential drug delivery systems based on polysaccharides." Thesis, University of Huddersfield, 2016. http://eprints.hud.ac.uk/id/eprint/32608/.

Full text

Abstract:

Enhancement of the drug efficacy and elimination of the side effects resulting from drug overdoses are an essential aspect in drug therapy. To achieve these demands two general guidelines have been used; producing new drugs with higher selectivity and therefore less side effects and improving controlled/sustained drug delivery agents based on polymers. Thus, the relationship between the active pharmaceutical ingredient and the polymeric system is important in the development of a drug delivery system and several considerations need to be taken in to account, for example the polymer should be b

APA, Harvard, Vancouver, ISO, and other styles

13

Gilliland, David. "Kinetic modelling of preservative systems." Thesis, Queen's University Belfast, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334622.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Keane, Harriet. "Network pharmacology of the MPP+ cellular model of Parkinson's disease." Thesis, University of Oxford, 2015. http://ora.ox.ac.uk/objects/uuid:1e18e521-c1a3-4f1b-9572-9c68e0f16c2f.

Full text

Abstract:

Parkinson's disease (PD) is an incurable neurodegenerative motor disorder caused by the inexorable loss of dopamine neurones from the substantia nigra pars compacta. Cell loss is characterised by the perturbation of multiple physiological processes (including mitochondrial function, autophagy and dopamine homeostasis) and much of this pathophysiology can be reproduced in vitro using the mitochondrial toxin MPP+ (1-methyl-4-phenylpyridinium). It was hypothesised that MPP+ toxicity could be modelled using protein-protein interaction networks (PPIN) in order to better understand the interplay of

APA, Harvard, Vancouver, ISO, and other styles

15

Trägårdh, Magnus. "Input estimation in nonlinear dynamical systems for drug-discovery applications." Thesis, University of Warwick, 2017. http://wrap.warwick.ac.uk/98556/.

Full text

Abstract:

In mathematical modelling for drug discovery, nonparametric methods are an alternative to the more commonly used parametric methods, and have the advantage of requiring fewer modelling assumptions. This thesis considers nonparametric methods for performing input estimation (deconvolution) -- inferring the input to a dynamical system based on measurements of the system’s state. A typical application is to determine the absorption profile of an orally administered drug. Commonly used input-estimation methods are restricted to system models that are linear. This thesis aims to develop and evaluat

APA, Harvard, Vancouver, ISO, and other styles

16

Tyreman, David R. "Peptide transport systems and antibiotic design." Thesis, Bangor University, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.277600.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Lee, Antony James. "Mathematical modelling of drug delivery systems." Thesis, University of Nottingham, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309563.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Royall, P. G. "Liposomes : partitioning and model drug systems." Thesis, University of Kent, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300949.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Lyons, Declan. "The renin-angiotensin system : interaction with other homeostatic systems in upper limb resistance vessels in man." Thesis, University of Aberdeen, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259669.

Full text

Abstract:

The thesis is concerned with the interaction of the renin-angiotensin system (RAS) with other homeostatic systems in the peripheral circulation of man. The activity of the RAS and is relationship to vascular tissue ACE, the arginine-nitric oxide system, the kallikrein-kinin system and the sympathetic nervous system are examined. The activity of a new orally active angiotensin (AT<sub>1</sub>) receptor antagonist and the regulation of AT receptors in response to low circulating angiotensin II concentrations are also assessed. Forearm venous occlusion plethysmography with mercury-in-silastic str

APA, Harvard, Vancouver, ISO, and other styles

20

Amer, Mahetab H. "Development of injectable cell delivery systems for high accuracy cell therapy applications." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/39839/.

Full text

Abstract:

Cell-based therapeutic interventions are being developed for a variety of clinical indications, including irreversible retinal pathologies and stroke. Numerous cell therapy procedures use injection-based administration to deliver high density cell preparations, either systemically or directly. The mode of delivery of fragile cells can compromise treatment efficacy, which is dependent on cell viability and functionality post-injection. Reviewing current literature, there is a lack of comprehensive testing of the effects of injection-based cell delivery on the various parameters of cell function

APA, Harvard, Vancouver, ISO, and other styles

21

Rodgers, Emily Sarah. "Polymeric nanoparticles as immunopotentiating antigen delivery systems." Thesis, Queen's University Belfast, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337114.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Lawlor, Michelle S. "Rheological characterisation of bioadhesive drug delivery systems." Thesis, Queen's University Belfast, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326370.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Dimitrijevic, Dejana. "Effects of surfactant systems on metformin transport." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300542.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Warnock, James Neill. "Optimisation of retroviral production systems for gene therapy applications." Thesis, University of Birmingham, 2003. http://etheses.bham.ac.uk//id/eprint/3592/.

Full text

Abstract:

Retroviral vectors are a promising tool for gene therapy. However, there are two major problems to overcome if a viable commercial production process is to be established. These are the instability of virus particles and the low virus titres. The characteristics of the producer cells were determined in batch culture, semicontinuous culture and semi-continuous culture at 32°C. Additionally, cell attachment, growth and virus production on various macroporous microcarriers was assessed under static and stirred conditions. Alternative strategies for the cultivation of cells were also investigated.

APA, Harvard, Vancouver, ISO, and other styles

25

Béïque, Jean-Claude. "The serotoninergic and noradrenergic systems : their involvement in the antidepressant effect." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0034/NQ64512.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Mahato, Ram Ishwar. "Preparation and characterisation of microparticulate drug delivery systems." Thesis, University of Strathclyde, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296914.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Dolan, T. F. "Drug delivery systems in the treatment of leishmaniasis." Thesis, University of Strathclyde, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.382260.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Pape, Valerie Elizabeth. "Methotrexate-protein conjugates as soluble drug delivery systems." Thesis, University of Bath, 1990. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.277877.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Van, Beek Hannah. "Inhibition of peroxide removal systems and ascorbate-induced cytotoxicity in pancreatic cancer." Thesis, University of Iowa, 2016. https://ir.uiowa.edu/etd/3205.

Full text

Abstract:

Compared to normal cells, cancer cells tend to have higher concentrations of reactive oxygen species (ROS) such as hydrogen peroxide (H2O2) due to an accelerated cellular metabolism. The high ROS content leaves cancer cells increasingly susceptible to oxidative stress-induced cell death. This susceptibility can be manipulated in selective cancer therapy by further increasing production of ROS or inhibiting peroxide removal systems or a combination of the two. Pharmacological ascorbate (high-dose intravenous ascorbate) has been shown to sensitize pancreatic cancer to ionizing radiation (IR) by

APA, Harvard, Vancouver, ISO, and other styles

30

Liu, Weipeng. "Biopolymer-based ocular drug delivery systems." Diss., Connect to online resource - MSU authorized users, 2008.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

31

Caston, Antony James. "The potential of fimbriae for bioadhesive drug delivery systems." Thesis, University of Nottingham, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315131.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Lim, Joseph G. P. "Studies of microparticulates as controlled pulmonary drug delivery systems." Thesis, Cardiff University, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.316267.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Williams, Winston W. "The effect of anaesthetics and pressure on membrane systems." Thesis, University of Salford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327999.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

McKerchar, Clare Elizabeth. "Neural systems involved in antipsychotic drug treatment and psychosis." Thesis, University of Strathclyde, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366791.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Maurya, Manisha. "The effect of antidepressants on rodent brain glucocorticoid systems." Thesis, Open University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368872.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Yusuff, Nahimot Titilayo. "Studies of cyclodextrin complexes for drug delivery - spironolactone : cyclodextrin systems." Thesis, University of Bradford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.364941.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Wakerly, M. G. "Self-emulsifying drug delivery systems based on nonionic surfactant-oil mixtures." Thesis, University of Bath, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.235402.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Fitzgerald, P. "An assessment of the precorneal residence of ophthalmic drug delivery systems." Thesis, University of Nottingham, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.356556.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Bland, Christopher Robert. "Evaluation of model systems to study the buccal absorption of drugs." Thesis, University of Nottingham, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.280290.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Ellis, B. "The fate of the antibiotic feed additive avoparcin in soil systems." Thesis, University of Portsmouth, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376098.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Chiappetta, Margaret Elizabeth. "Knowledge translation in action : cancer biology and systems pharmacology at the National Center for Advancing Translational Science." Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/50189.

Full text

Abstract:

The need for novel diagnostic and therapeutic drugs with the potential to combat increasingly prevalent or particularly insidious diseases has grown in recent years. Concurrently, the issue of translating scientific knowledge from “bench to bedside” has become increasingly salient. In 2011, the U.S. National Institutes of Health created the National Center for Advancing Translational Science in an effort to remedy the recalcitrant gaps between fundamental laboratory research and late-stage clinical trial, thereby dramatically reducing the amount of time and expense needed to develop efficaciou

APA, Harvard, Vancouver, ISO, and other styles

42

Anlind, Alice. "Improvments and evaluation of data processing in LC-MS metabolomics : for application in in vitro systems pharmacology." Thesis, Uppsala universitet, Institutionen för biologisk grundutbildning, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-329971.

Full text

Abstract:

The resistance of established medicines is rapidly increasing while the rate of discovery of new drugs and treatments have not increases during the last decades (Spiro et al. 2008). Systems pharmacology can be used to find new combinations or concentrations of established drugs to find new treatments faster (Borisy et al. 2003). A recent study aimed to use high resolution Liquid chromatography–mass spectrometry (LC-MS) for in vitro systems pharmacology, but encountered problems with unwanted variability and batch effects(Herman et al. 2017). This thesis builds on this work by improving the pip

APA, Harvard, Vancouver, ISO, and other styles

43

Duwal, Sulav [Verfasser]. "A multiscale systems pharmacology framework to assess the prophylactic utility of antivirals against HIV-1 / Sulav Duwal." Berlin : Freie Universität Berlin, 2019. http://d-nb.info/1180387937/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Cordes, Henrik [Verfasser], Lars Mathias [Akademischer Betreuer] Blank, and Rodríguez Julio [Akademischer Betreuer] Sáez. "Multi-scale modeling in human systems pharmacology & physiology / Henrik Cordes ; Lars Mathias Blank, Julio Sáez Rodríguez." Aachen : Universitätsbibliothek der RWTH Aachen, 2019. http://d-nb.info/1194066887/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Birgner, Carolina. "Anabolic androgenic steroids and central monoaminergic systems : Supratherapeutic doses of nandrolone decanoate affect dopamine and serotonin." Doctoral thesis, Uppsala University, Department of Pharmaceutical Biosciences, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9208.

Full text

Abstract:

<p>Supratherapeutic doses of anabolic androgenic steroids (AASs) are administered, not only as performance-enhancing drugs in the world of sports, but also in order to modify behaviour. AAS abusers are at risk of developing serious physical and psychological side effects such as dependence and aggressive behaviour. The aim of this thesis was to investigate the impact of supratherapeutic doses of nandrolone decanoate after subchronic administration on dopamine and serotonin pathways involved in drug dependence and aggression, in the male rat brain.</p><p>Adult male Sprague-Dawley rats received

APA, Harvard, Vancouver, ISO, and other styles

46

Mongeau, Raymond. "The serotonergic and noradrenergic systems of the hippocampus : their interactions and the effects of antidepressant treatments." Thesis, McGill University, 1994. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=28856.

Full text

Abstract:

Since the formulation of the monoaminergic hypotheses of depression, several investigations have established that the serotonin (5-HT) as well as the noradrenaline (NA) systems are altered by antidepressant treatments. In the last few years, several studies have indicated that interactions between these two systems might also be important in the mechanism of action of antidepressant drugs. We have thus undertaken: (1) to elucidate the nature of some interactions between the 5-HT and NA systems in the rat hippocampus using in vivo electrophysiology and in vitro superfusion techniques; and (2) t

APA, Harvard, Vancouver, ISO, and other styles

47

Dordunoo, Stephen Kwaku. "Characterization of drug-carrier systems for liquid filling of hard gelatin capsules." Thesis, Liverpool John Moores University, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.261411.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Kemp, Philip Arthur. "The development of novel antibodies fragments for use in pharmaceutical biodetection systems." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287547.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Plumb, Robert Stephen. "Development of novel generic analytical systems for the study of drug metabolism." Thesis, University of Hertfordshire, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302299.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

Mahdi, Mohammed Hamzah. "Development of gellan gum fluid gel as modified release drug delivery systems." Thesis, University of Huddersfield, 2016. http://eprints.hud.ac.uk/id/eprint/30293/.

Full text

Abstract:

Gelation of polysaccharides under shear conditions results in the formation of a weak gel which is able to resist elastic mechanical deformation at small strains but will flow if subjected to higher strains. The resulting material, described in the literature as a fluid gel or a sheared gel, consists of gelled microparticles which can be formulated to collectively act in bulk, as pourable viscoelastic fluids whilst retaining true gel characteristics at the micro/nano level. The tuneable behaviour of these fluid gel systems makes them potentially useful in pharmaceutical applications. Fluid gel

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!