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Journal articles on the topic 'Systems pharmacology'

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1

Boran, Aislyn D. W., and Ravi Iyengar. "Systems Pharmacology." Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine 77, no. 4 (2010): 333–44. http://dx.doi.org/10.1002/msj.20191.

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2

Mortin, Lawrence I., Christopher J. Horvath, and Michael S. Wyand. "Safety Pharmacology Screening: Practical Problems in Drug Development." International Journal of Toxicology 16, no. 1 (1997): 41–65. http://dx.doi.org/10.1080/109158197227350.

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Undesired pharmacologic activities of novel drugs or biologies may limit development of a therapeutic prior to the characterization of any toxicologic effects. In rodent species, general pharmacology assays have traditionally been used to screen new agents for pharmacologic effects on the central and peripheral nervous systems, the autonomic nervous system and smooth muscles, the respiratory and cardiovascular systems, the digestive system, and the physiologic mechanisms of water and electrolyte balance. In large animal species, such as dogs and nonhuman primates, smaller numbers of animals pe
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3

Atkinson, A. J., and P. M. Lyster. "Systems Clinical Pharmacology." Clinical Pharmacology & Therapeutics 88, no. 1 (2010): 3–6. http://dx.doi.org/10.1038/clpt.2010.88.

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4

Berg, J. M., M. E. Rogers, and P. M. Lyster. "Systems Biology and Pharmacology." Clinical Pharmacology & Therapeutics 88, no. 1 (2010): 17–19. http://dx.doi.org/10.1038/clpt.2010.69.

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5

Chen, Yu, Timothy S. Kern, Philip D. Kiser, and Krzysztof Palczewski. "Eyes on systems pharmacology." Pharmacological Research 114 (December 2016): 39–41. http://dx.doi.org/10.1016/j.phrs.2016.09.026.

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6

Berger, S. I., A. Ma'ayan, and R. Iyengar. "Systems Pharmacology of Arrhythmias." Science Signaling 3, no. 118 (2010): ra30. http://dx.doi.org/10.1126/scisignal.2000723.

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7

van der Graaf, Piet H. "Systems Pharmacology and Pharmacodynamics." CPT: Pharmacometrics & Systems Pharmacology 6, no. 12 (2017): 803. http://dx.doi.org/10.1002/psp4.12231.

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8

Kaddurah-Daouk, R., and R. M. Weinshilboum. "Pharmacometabolomics: Implications for Clinical Pharmacology and Systems Pharmacology." Clinical Pharmacology & Therapeutics 95, no. 2 (2013): 154–67. http://dx.doi.org/10.1038/clpt.2013.217.

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9

Panteleev, M. A., A. N. Sveshnikova, A. V. Belyaev, et al. "Systems Biology and Systems Pharmacology of Thrombosis." Mathematical Modelling of Natural Phenomena 9, no. 6 (2014): 4–16. http://dx.doi.org/10.1051/mmnp/20149602.

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10

Gadkar, K., D. Kirouac, N. Parrott, and S. Ramanujan. "Quantitative systems pharmacology: a promising approach for translational pharmacology." Drug Discovery Today: Technologies 21-22 (September 2016): 57–65. http://dx.doi.org/10.1016/j.ddtec.2016.11.001.

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11

Lombardo, Rosario, and Corrado Priami. "Graphical Modeling Meets Systems Pharmacology." Gene Regulation and Systems Biology 11 (January 2017): 117762501769193. http://dx.doi.org/10.1177/1177625017691937.

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12

van der Graaf, Piet H. "CPT: Pharmacometrics and Systems Pharmacology." CPT: Pharmacometrics & Systems Pharmacology 1, no. 9 (2012): 8. http://dx.doi.org/10.1038/psp.2012.8.

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13

Waldman, SA, PH van der Graaf, and A. Terzic. "Systems Approaches Evolve Clinical Pharmacology." CPT: Pharmacometrics & Systems Pharmacology 2, no. 8 (2013): 68. http://dx.doi.org/10.1038/psp.2013.48.

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14

FitzGerald, Garret A. "Systems Pharmacology and Translational Therapeutics." Proceedings for Annual Meeting of The Japanese Pharmacological Society WCP2018 (2018): CL—8. http://dx.doi.org/10.1254/jpssuppl.wcp2018.0_cl-8.

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15

Waldman, S. A., and A. Terzic. "Advancing Pharmacometrics and Systems Pharmacology." Clinical Pharmacology & Therapeutics 92, no. 5 (2012): 535–37. http://dx.doi.org/10.1038/clpt.2012.151.

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16

Hennefer, Dawn, and Elizabeth Lawson. "Pharmacology - a systems approach: introduction." British Journal of Healthcare Assistants 3, no. 2 (2009): 92–95. http://dx.doi.org/10.12968/bjha.2009.3.2.39396.

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17

Berger, S. I., and R. Iyengar. "Network analyses in systems pharmacology." Bioinformatics 25, no. 19 (2009): 2466–72. http://dx.doi.org/10.1093/bioinformatics/btp465.

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18

Hansen, Jens, Shan Zhao, and Ravi Iyengar. "Systems pharmacology of complex diseases." Annals of the New York Academy of Sciences 1245, no. 1 (2011): E1—E5. http://dx.doi.org/10.1111/j.1749-6632.2011.06382.x.

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19

Schadrack, J., and W. Zieglg�nsberger. "Pharmacology of pain processing systems." Zeitschrift f�r Rheumatologie 57, no. 8 (1998): S1—S4. http://dx.doi.org/10.1007/s003930050224.

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20

Mentré, France, Lena E. Friberg, Stephen Duffull, et al. "Pharmacometrics and Systems Pharmacology 2030." Clinical Pharmacology & Therapeutics 107, no. 1 (2019): 76–78. http://dx.doi.org/10.1002/cpt.1683.

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21

Graaf, Piet H. "Pharmacometrics and/or Systems Pharmacology." CPT: Pharmacometrics & Systems Pharmacology 8, no. 6 (2019): 331–32. http://dx.doi.org/10.1002/psp4.12376.

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22

Topp, Brian, Maria E. Trujillo, and Vikram Sinha. "Industrialization of Quantitative Systems Pharmacology." CPT: Pharmacometrics & Systems Pharmacology 8, no. 6 (2019): 356–58. http://dx.doi.org/10.1002/psp4.12427.

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23

Ribeiro, C. A. Fontes. "Pharmacology of serotonin neuronal systems." Human Psychopharmacology: Clinical and Experimental 6, S1 (1991): S37—S51. http://dx.doi.org/10.1002/hup.470060508.

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24

Kushwaha, Dr Virendra, Dr Pooja Agrawal, Dr Vipul Shukla, and Dr Geeta Singh Rana. "Quantitative Systems Pharmacology: An Overview." International Journal of pharma and Bio Sciences 14, no. 4 (2023): 89–100. http://dx.doi.org/10.22376/ijpbs.2023.14.4.p89-100.

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25

Stéphanou, Angélique, Eric Fanchon, Pasquale F. Innominato, and Annabelle Ballesta. "Systems Biology, Systems Medicine, Systems Pharmacology: The What and The Why." Acta Biotheoretica 66, no. 4 (2018): 345–65. http://dx.doi.org/10.1007/s10441-018-9330-2.

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26

Furutani, Kazuharu, and Yoshihisa Kurachi. "Systems pharmacology for cardiac ion channels." Drug Delivery System 29, no. 5 (2014): 397–407. http://dx.doi.org/10.2745/dds.29.397.

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27

Xie, Lei, Eli J. Draizen, and Philip E. Bourne. "Harnessing Big Data for Systems Pharmacology." Annual Review of Pharmacology and Toxicology 57, no. 1 (2017): 245–62. http://dx.doi.org/10.1146/annurev-pharmtox-010716-104659.

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28

Hennefer, Dawn, and Elizabeth Lawson. "Pharmacology - a systems approach: female hormones." British Journal of Healthcare Assistants 3, no. 10 (2009): 498–501. http://dx.doi.org/10.12968/bjha.2009.3.10.44587.

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29

Hennefer, Dawn, and Elizabeth Lawson. "Pharmacology - a systems approach: respiratory system." British Journal of Healthcare Assistants 3, no. 3 (2009): 148–51. http://dx.doi.org/10.12968/bjha.2009.3.3.40598.

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30

Hennefer, Dawn, and Elizabeth Lawson. "Pharmacology- a systems approach: gastrointestinal tract." British Journal of Healthcare Assistants 3, no. 6 (2009): 295–99. http://dx.doi.org/10.12968/bjha.2009.3.6.42795.

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31

Hennefer, Dawn, and Elizabeth Lawson. "Pharmacology - a systems approach: endocrine system." British Journal of Healthcare Assistants 3, no. 8 (2009): 393–96. http://dx.doi.org/10.12968/bjha.2009.3.8.43672.

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32

Hennefe, Dawn, and Elizabeth Lawson. "Pharmacology - a systems approach: thyroid disease." British Journal of Healthcare Assistants 3, no. 9 (2009): 457–59. http://dx.doi.org/10.12968/bjha.2009.3.9.43991.

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33

Hennefer, Dawn, and Elizabeth Lawson. "Pharmacology - a systems approach: renal system." British Journal of Healthcare Assistants 4, no. 1 (2010): 38–41. http://dx.doi.org/10.12968/bjha.2010.4.1.46073.

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34

López, Julio, Fabiola de la Cruz, Yolanda Alcaraz, Francisco Delgado, and Miguel A. Vázquez. "Quinoid systems in chemistry and pharmacology." Medicinal Chemistry Research 24, no. 10 (2015): 3599–620. http://dx.doi.org/10.1007/s00044-015-1412-y.

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35

Romero-Canelón, Isolda, and Peter J. Sadler. "Systems approach to metal-based pharmacology." Proceedings of the National Academy of Sciences 112, no. 14 (2015): 4187–88. http://dx.doi.org/10.1073/pnas.1503858112.

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36

Westerhoff, Hans V. "Network-based pharmacology through systems biology." Drug Discovery Today: Technologies 15 (August 2015): 15–16. http://dx.doi.org/10.1016/j.ddtec.2015.05.001.

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37

Lorberbaum, T., M. Nasir, MJ Keiser, S. Vilar, G. Hripcsak, and NP Tatonetti. "Systems Pharmacology Augments Drug Safety Surveillance." Clinical Pharmacology & Therapeutics 97, no. 2 (2014): 151–58. http://dx.doi.org/10.1002/cpt.2.

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38

Bloomingdale, Peter, Van Anh Nguyen, Jin Niu, and Donald E. Mager. "Boolean network modeling in systems pharmacology." Journal of Pharmacokinetics and Pharmacodynamics 45, no. 1 (2018): 159–80. http://dx.doi.org/10.1007/s10928-017-9567-4.

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39

Cosgrove, J., J. Butler, K. Alden, et al. "Agent-Based Modeling in Systems Pharmacology." CPT: Pharmacometrics & Systems Pharmacology 4, no. 11 (2015): 615–29. http://dx.doi.org/10.1002/psp4.12018.

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40

Traynard, Pauline, Luis Tobalina, Federica Eduati, Laurence Calzone, and Julio Saez-Rodriguez. "Logic Modeling in Quantitative Systems Pharmacology." CPT: Pharmacometrics & Systems Pharmacology 6, no. 8 (2017): 499–511. http://dx.doi.org/10.1002/psp4.12225.

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41

Mentré, France. "CPT: Pharmacometrics & Systems Pharmacology 2.0." CPT: Pharmacometrics & Systems Pharmacology 8, no. 4 (2019): 195–96. http://dx.doi.org/10.1002/psp4.12396.

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42

Ma’ayan, Avi, Andrew D. Rouillard, Neil R. Clark, Zichen Wang, Qiaonan Duan, and Yan Kou. "Lean Big Data integration in systems biology and systems pharmacology." Trends in Pharmacological Sciences 35, no. 9 (2014): 450–60. http://dx.doi.org/10.1016/j.tips.2014.07.001.

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43

van der Greef, Jan, and Robert N. McBurney. "Rescuing drug discovery: in vivo systems pathology and systems pharmacology." Nature Reviews Drug Discovery 4, no. 12 (2005): 961–67. http://dx.doi.org/10.1038/nrd1904.

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44

Sobie, E. A., S. L. Jenkins, R. Iyengar, and T. A. Krulwich. "Training in Systems Pharmacology: Predoctoral Program in Pharmacology and Systems Biology at Mount Sinai School of Medicine." Clinical Pharmacology & Therapeutics 88, no. 1 (2010): 19–22. http://dx.doi.org/10.1038/clpt.2010.41.

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45

Zhou, Wei, Yonghua Wang, Aiping Lu, and Ge Zhang. "Systems Pharmacology in Small Molecular Drug Discovery." International Journal of Molecular Sciences 17, no. 2 (2016): 246. http://dx.doi.org/10.3390/ijms17020246.

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46

Chang, Roger L., Lei Xie, Philip E. Bourne, and Bernhard O. Palsson. "Antibacterial mechanisms identified through structural systems pharmacology." BMC Systems Biology 7, no. 1 (2013): 102. http://dx.doi.org/10.1186/1752-0509-7-102.

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47

Krzyzanski, W. "Systems Pharmacology Models for Guiding Drug Design." CPT: Pharmacometrics & Systems Pharmacology 2, no. 4 (2013): 39. http://dx.doi.org/10.1038/psp.2013.15.

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48

D'Argenio, David Z., and Donald E. Mager. "Bridging Pharmacology and Pathophysiology via Systems Modeling." Journal of Clinical Pharmacology 50, S9 (2010): 56S—57S. http://dx.doi.org/10.1177/0091270010377505.

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49

Cirit, Murat. "Quantitative pharmacology studies in microphysiological systems (MPS)." Drug Metabolism and Pharmacokinetics 33, no. 1 (2018): S66. http://dx.doi.org/10.1016/j.dmpk.2017.11.221.

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50

Androulakis, Ioannis P. "Quantitative Systems Pharmacology: A Framework for Context." Current Pharmacology Reports 2, no. 3 (2016): 152–60. http://dx.doi.org/10.1007/s40495-016-0058-x.

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