Academic literature on the topic 'T cell transfer'

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Journal articles on the topic "T cell transfer"

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Sharma, Preeti, and David M. Kranz. "T Cell Receptors for Gene Transfer in Adoptive T Cell Therapy." Critical Reviews in Immunology 39, no. 2 (2019): 105–22. http://dx.doi.org/10.1615/critrevimmunol.2019030788.

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Berger, Carolina, Michael C. Jensen, and Stanley R. Riddell. "Establishing T Cell Memory by Adoptive Transfer of T Cell Clones." Blood 108, no. 11 (2006): 866. http://dx.doi.org/10.1182/blood.v108.11.866.866.

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Abstract Adoptive transfer of T cells has been employed to reconstitute T cell immunity to viruses such as cytomegalovirus (CMV) in immunodeficient allogeneic stem cell transplant (SCT) patients and is being investigated to treat malignancies. In the allogeneic SCT setting, the T cells are derived from the donor and need to be isolated as clones or highly pure populations to avoid graft-versus-host disease. CD8+ T cells can be divided into defined subsets including CD62L− effector memory (TEM) and central memory T cells (TCM) expressing the CD62L lymph node homing molecule. Both TCM and TEM ca
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Itzhaki, Orit, Daphna Levy, Dragoslav Zikich, et al. "Adoptive T-cell transfer in melanoma." Immunotherapy 5, no. 1 (2013): 79–90. http://dx.doi.org/10.2217/imt.12.143.

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Kessels, Helmut W. H. G., Monika C. Wolkers, and Ton N. M. Schumacher. "Adoptive transfer of T-cell immunity." Trends in Immunology 23, no. 5 (2002): 264–69. http://dx.doi.org/10.1016/s1471-4906(02)02219-6.

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Chakrabarti, Indranil. "T-cell transfer therapy: A primer." IP Journal of Diagnostic Pathology and Oncology 8, no. 3 (2023): 127–29. http://dx.doi.org/10.18231/j.jdpo.2023.030.

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Conrad, Heinke, Peter Meyerhuber, Barbara Kast, et al. "Redirection of human T lymphocytes towards HER2 by T cell receptor gene transfer for adoptive T cell transfer (41.6)." Journal of Immunology 182, no. 1_Supplement (2009): 41.6. http://dx.doi.org/10.4049/jimmunol.182.supp.41.6.

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Abstract The clinical goal of our studies is the adoptive transfer of primary T cells transduced with a HER2-specific T cell receptor (TCR) for patients with HER2-overexpressing breast cancer. HLA-A2-, CD8 T cells were stimulated with allogeneic HLA-A2+ dendritic cells (DC) pulsed with the peptide HER2369-377. HER2369-377-reactive T cells were screened, cloned and further tested in functional assays. The TCR from the HER2-reactive CTL clone KU1 was cloned into a retrovirus. Primary T lymphocytes were transduced with this construct and functionally compared with the parental CTL clone KU1. The
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Chapman, Paul B. "Programming T cells for adoptive T cell transfer therapy." Pigment Cell & Melanoma Research 23, no. 2 (2010): 155–56. http://dx.doi.org/10.1111/j.1755-148x.2010.00681.x.

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Isser, Ariel, and Jonathan P. Schneck. "High-affinity T cell receptors for adoptive cell transfer." Journal of Clinical Investigation 129, no. 1 (2018): 69–71. http://dx.doi.org/10.1172/jci125471.

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Han, Fei, Emilia R. Dellacecca, Levi W. Barse, et al. "Adoptive T-Cell Transfer to Treat Lymphangioleiomyomatosis." American Journal of Respiratory Cell and Molecular Biology 62, no. 6 (2020): 793–804. http://dx.doi.org/10.1165/rcmb.2019-0117oc.

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Tey, Siok‐Keen, Catherine M. Bollard, and Helen E. Heslop. "Adoptive T‐cell transfer in cancer immunotherapy." Immunology & Cell Biology 84, no. 3 (2006): 281–89. http://dx.doi.org/10.1111/j.1440-1711.2006.01441.x.

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Dissertations / Theses on the topic "T cell transfer"

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Sommermeyer, Daniel. "Generation of dual T cell receptor (TCR) T cells by TCR gene transfer for adoptive T cell therapy." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2010. http://dx.doi.org/10.18452/16051.

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Die Herstellung von T-Zellen mit definierten Spezifitäten durch den Transfer von T-Zellrezeptor (TCR) Genen ist eine effiziente Methode, um Zellen für eine Immuntherapie bereitzustellen. Eine besondere Herausforderung ist dabei, ein ausreichend hohes Expressionsniveau des therapeutischen TCR zu erreichen. Da T-Zellen mit einem zusätzlichen TCR ausgestattet werden, entsteht eine Konkurrenzsituation zwischen dem therapeutischen und dem endogenen TCR. Bevor diese Arbeit begonnen wurde war nicht bekannt, welche TCR nach einem Gen-Transfer exprimiert werden. Daher haben wir Modelle etabliert, in de
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Wright, G. P. "Generation of antigen-specific regulatory T cells by T cell receptor gene transfer." Thesis, University College London (University of London), 2009. http://discovery.ucl.ac.uk/18952/.

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Regulatory T cells (Tregs) have shown considerable potential in the treatment of murine models of immuno-pathology. Whilst poly-clonal Tregs are able to suppress immuno-pathology in a number of models, the superiority of Ag-specific Treg treatment has been demonstrated using Tregs from T cell receptor (TCR)- transgenic animals. Translation of these promising results to the clinic has been hampered by difficulties in isolating or enriching the rare Ag-specific Tregs from the polyclonal population. Here I describe two distinct approaches to generate Ag-specific T cells with regulatory ability: f
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Bracq, Lucie. "Analysis of HIV-1 cell-to-cell transfer to macrophages." Thesis, Sorbonne Paris Cité, 2017. http://www.theses.fr/2017USPCB063/document.

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Les macrophages sont une cible particulièrement importante de l’infection par le VIH-1 et jouent un rôle crucial dans la physiopathologie de l’infection. Lorsqu’ils sont infectés, leur capacité de survie dans les tissus leur permet de jouer un rôle essentiel dans la dissémination virale et l’établissement de réservoirs viraux au niveau des différents territoires tissulaires. In vitro, les étapes précoces et tardives du cycle de réplication virale dans les macrophages ont été analysées dans le cadre de l’infection par des virus libres. Cependant, les modalités d’infection des macrophages lors d
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Böhm, Stefanie [Verfasser], and Lars [Akademischer Betreuer] Nitschke. "Adoptive T-cell-receptor transfer to examine human T-cell immunology in vitro / Stefanie Böhm. Betreuer: Lars Nitschke." Erlangen : Universitätsbibliothek der Universität Erlangen-Nürnberg, 2013. http://d-nb.info/1033688193/34.

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Chakupurakal, Geothy. "Preclinical studies of adenovirus-specific T-cells for adoptive transfer to haemopoietic stem cell transplant recipients." Thesis, University of Birmingham, 2011. http://etheses.bham.ac.uk//id/eprint/2883/.

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Allogeneic stem cell transplantation (SCT) is the only curative treatment option for many haematological malignancies. Adenovirus (Ad) infections are a significant cause of morbidity and mortality post SCT. Lack of effective anti-viral treatment for Ad disease has led to the development of adoptive immunotherapy of Ad-specific T-cells as a promising therapeutic option for patients in this setting. The aim of this project was to establish preclinical criteria for the development of a clinical trial comparing two T-cell enrichment methods- multimer selection and cytokine secretion selection to e
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Carluccio, S. "GENERATION OF TUMOR-SPECIFIC CYTOTOXIC T-LYMPHOCYTES FROM PEROPHERAL BLOOD OF COLORECTAL CANCER PATIENTS FOR ADOPTIVE T-CELL TRANSFER." Doctoral thesis, Università degli Studi di Milano, 2014. http://hdl.handle.net/2434/231155.

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Colorectal cancer (CRC) is the third most common cancer worldwide and the fourth most common cause of death in the developed Western countries. Adoptive T-cell transfer (ACT) refers to an immunotherapeutic approach in which anti-tumor T lymphocytes, usually the tumor infiltrating lymphocytes (TIL), are identified, grown ex vivo and then re-infused into the cancer patient. ACT of EBV-specific T-cell lines and T Cytotoxic Lymphocytes (CTLs) for the therapy of EBV-induced lymphomas is the best demonstration of clinically efficacious ACT, but there are many evidences also for leukemia and multi
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Gräf, Patricia [Verfasser]. "Serial transfer of single cell-derived immunocompetence reveals stemness of CD8+ central memory T cells / Patricia Gräf." München : Verlag Dr. Hut, 2015. http://d-nb.info/1070124389/34.

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Akhter, Waseem. "Le rôle du transfert de mitochondries des cellules stromales mésenchymateuses (CSM) dans la suppression des réponses des cellules T CD4+ et CD8+." Thesis, Université de Montpellier (2022-….), 2022. http://www.theses.fr/2022UMONT011.

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Les lymphocytes T cytotoxiques CD8+ (LTC) et les cellules T helper CD4+ sont des effecteurs clés dans les maladies auto-immunes, les maladies du greffon contre l'hôte et le rejet de greffe. Les cellules stromales mésenchymateuses (CSM) sont des cellules multipotentes auto-renouvelables qui possèdent des propriétés de réparation tissulaire et d'immunomodulation. En raison de leur capacité à réprimer les réponses immunitaires pathogènes, elles présentent un potentiel thérapeutique pour le traitement des maladies à médiation immunitaire. Les CSMs ont la capacité unique d'exporter leurs propres mi
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Uhlig, Holm H. "Intestinal bacterial flora and the inflammatory immune response in the T cell transfer model of colitis." Thesis, University of Oxford, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.403771.

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Petschenka, Jutta [Verfasser]. "Safety and therapeutic efficacy of adoptive p53-specific T cell antigen receptor (TCR) gene transfer / Jutta Petschenka." Mainz : Universitätsbibliothek Mainz, 2014. http://d-nb.info/1052080685/34.

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Books on the topic "T cell transfer"

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Lee, Paul H. Effects of adoptive transfer of OSP A-specific TH2 T cells on the evolution of lyme borreliosis in mice. s.n.], 1995.

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Kang, Joonsoo. Analysis of T cell receptor-antigen interaction using retrovirus-mediated gene transfer. 1994.

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Book chapters on the topic "T cell transfer"

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Wang, Mingjun. "Adoptive T Cell Transfer." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-27841-9_7111-1.

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Shaffer, Donald R., Conrad Russell Y. Cruz, and Cliona M. Rooney. "Adoptive T Cell Transfer." In Cancer Immunotherapy. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-4732-0_3.

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Wang, Mingjun. "Adoptive T-Cell Transfer." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-662-46875-3_7111.

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Newrzela, Sebastian, Brandenburg Gunda, and Dorothee von Laer. "T Cell Culture for Gammaretroviral Transfer." In Genetic Modification of Hematopoietic Stem Cells. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-59745-409-4_6.

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Bonini, Chiara, Marina Cavazzana, Fabio Ciceri, Boris Fehse, and Michael Hudecek. "Cellular Therapy with Engineered T Cells, Efficacy, and Side Effects: Gene Editing/Gene Therapy." In The EBMT Handbook. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-44080-9_60.

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AbstractThe cellular basis of cancer immune surveillance, already hypothesized in ancient times, was only proven with the advent of HCT. Indeed, the discovery of the nature of GVHD and its antileukemic effects (Weiden et al. 1979) was followed by the first successful attempts of adoptive immunotherapy using donor leukocytes (Kolb et al. 1990). To address the significant GVHD risk associated with allogeneic T cells, several approaches of T-cell manipulation were developed and tested (Table 60.1). Some of these strategies rely on the genetic manipulation of T cells. First, suicide gene therapy a
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Holtick, Udo, and Elie Azoulay. "ICU." In The EBMT/EHA CAR-T Cell Handbook. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-94353-0_31.

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AbstractCAR-T cell treatment comes with significant side effects that challenge the structure and capacity of haematology wards and will regularly necessitate intermittent patient transfer to the ICU. Life-threatening adverse events include cytokine release syndrome and immune effector cell-associated neurotoxicity syndrome, which can occur within hours or days after administration. Sepsis might also require ICU admission within the days that follow CAR-T infusion in these high-risk immunocompromised patients.
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Miyazaki, Yumi, and Shunichi Shiozawa. "In Vivo Cell Transfer Assay to Detect Autoreactive T Cell Subsets." In Methods in Molecular Biology. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0404-4_6.

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Banerjee, Daliya, and Motomu Shimaoka. "Lentiviral Gene Transfer Method to Study Integrin Function in T Lymphocytes." In Integrin and Cell Adhesion Molecules. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-166-6_4.

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Slater, S., U. Kreuzburg-duffy, R. Jaggar, and C. Macdonald. "Transfer of SV40 - T Expression Vectors into Human Monocytes." In Animal Cell Technology: Developments Towards the 21st Century. Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-0437-1_14.

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Lugli, Enrico, and Luca Gattinoni. "Harnessing Stem Cell-Like Memory T Cells for Adoptive Cell Transfer Therapy of Cancer." In Cancer Drug Discovery and Development. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-21167-1_8.

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Conference papers on the topic "T cell transfer"

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Wilking, Alice, Lili Wang, Benjamin K. Chen, Thomas Huser, and Wolfgang Hubner. "Resolving T cell — T cell transfer of HIV-1 by optical nanoscopy." In 2017 Conference on Lasers and Electro-Optics Europe (CLEO/Europe) & European Quantum Electronics Conference (EQEC). IEEE, 2017. http://dx.doi.org/10.1109/cleoe-eqec.2017.8087773.

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Kristensen, Nikolaj Pagh, Christina Heeke, Siri A. Tvingsholm, et al. "Abstract A14: Neoepitope-specific CD8+ T cells in adoptive T-cell transfer." In Abstracts: AACR Special Conference on Tumor Immunology and Immunotherapy; November 17-20, 2019; Boston, MA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/2326-6074.tumimm19-a14.

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Kephart, Jacob, and G. F. Jones. "Material Distribution Optimization in a Metal Matrix Heat Sink Using a Constructal-Design Inspired Unit T-Cell." In ASME 2017 Heat Transfer Summer Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/ht2017-4950.

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Constructal principles are used to investigate the optimization of material utilization in a metal matrix heat sink that maximizes the total heat transfer rate through the base of heat sink. This approach utilizes a two-dimensional geometry to examine spatial heat flow and optimal material distribution in a metal matrix in the plane perpendicular to the coolant flow direction. The matrix is composed of multiple layers of conductive tees built up from the smallest constituent, the unit T-cell. The unit cell consists of a conductive tee-shaped geometry with the two rectangular void regions each
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Inderberg, Else M., Sébastien Wälchli, Marit R. Myhre, Kari Lislerud, Gunnar Kvalheim, and Gustav Gaudernack. "Abstract 2310: With a little help from CD4 T cells in adoptive T-cell transfer." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-2310.

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Heeke, Christina, Anne-Mette Bjerregaard, Amalie Kai Bentzen, et al. "Abstract B015: T-cell recognition profiling of CD8+ T-cells in tumor-infiltrating lymphocytes expanded for adoptive cell transfer." In Abstracts: Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival; September 30 - October 3, 2018; New York, NY. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/2326-6074.cricimteatiaacr18-b015.

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Howsmon, Daniel, Juergen Hahn, Shelby Steinmeyer, Arul Jayaraman, and Robert Alaniz. "Neural networks elucidate T cell priming conditions for adoptive transfer." In 2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC). IEEE, 2015. http://dx.doi.org/10.1109/nebec.2015.7117044.

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Cooper, Laurence. "Abstract IA47: Nonviral gene transfer to redirect T cell specificity." In Abstracts: CRI-CIMT-EATI-AACR Inaugural International Cancer Immunotherapy Conference: Translating Science into Survival; September 16-19, 2015; New York, NY. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/2326-6074.cricimteatiaacr15-ia47.

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Rylander, M. Nichole, Kenneth R. Diller, Sihong Wang, and Shanti J. Aggarwal. "Correlation of HSP70 Expression and Cell Viability Following Thermal Stimulation of Aortic Endothelial Cells." In ASME 2004 Heat Transfer/Fluids Engineering Summer Conference. ASMEDC, 2004. http://dx.doi.org/10.1115/ht-fed2004-56383.

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The goal of this study was to determine the kinetics of HSP70 expression and variations in cell viability resulting from thermal preconditioning of the heart. Experiments were conducted to determine combinations of elevated temperatures and brief heating durations that could produce enhanced HSP70 levels while maintaining high cell viability. Bovine aortic endothelial cells were heated with a water bath at temperatures ranging from 44–50°C and periods of 1–30 min consistent with anticipated protocols for cardiac preconditioning prior to surgery. Western blot and cell adhesion analysis in cultu
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Kakimi, Kazuhiro, Tomohiro Murakawa, Takeshi Fukami та ін. "Abstract 1926: Adoptive γδ T cell transfer therapy for non-small cell lung cancer". У Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-1926.

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Mittal, Tarun, Siddharth Saroha, Vishal Bhalla, et al. "Numerical Study of Solar Photovoltaic/Thermal (PV/T) Hybrid Collector Using Nanofluids." In ASME 2013 4th International Conference on Micro/Nanoscale Heat and Mass Transfer. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/mnhmt2013-22090.

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The commonly used methods to harness solar energy are solar thermal and solar photovoltaic (PV). A new category photovoltaic/thermal (PV/T) hybrid combines these two technologies, and achieves higher combined efficiency. The challenge is to keep the operating temperature of the PV low and at the same time not compromise on the temperature of the thermal cycle. Various designs of PV/T hybrids (both flat plate and concentrated) have already been proposed which utilize air or water to remove the heat from PV cells in order to enhance the overall efficiency of PV/T hybrid collector. Recent papers
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Reports on the topic "T cell transfer"

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Tzfira, Tzvi, Michael Elbaum, and Sharon Wolf. DNA transfer by Agrobacterium: a cooperative interaction of ssDNA, virulence proteins, and plant host factors. United States Department of Agriculture, 2005. http://dx.doi.org/10.32747/2005.7695881.bard.

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Agrobacteriumtumefaciensmediates genetic transformation of plants. The possibility of exchanging the natural genes for other DNA has led to Agrobacterium’s emergence as the primary vector for genetic modification of plants. The similarity among eukaryotic mechanisms of nuclear import also suggests use of its active elements as media for non-viral genetic therapy in animals. These considerations motivate the present study of the process that carries DNA of bacterial origin into the host nucleus. The infective pathway of Agrobacterium involves excision of a single-stranded DNA molecule (T-strand
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Ron, Eliora, and Eugene Eugene Nester. Global functional genomics of plant cell transformation by agrobacterium. United States Department of Agriculture, 2009. http://dx.doi.org/10.32747/2009.7695860.bard.

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The aim of this study was to carry out a global functional genomics analysis of plant cell transformation by Agrobacterium in order to define and characterize the physiology of Agrobacterium in the acidic environment of a wounded plant. We planed to study the proteome and transcriptome of Agrobacterium in response to a change in pH, from 7.2 to 5.5 and identify genes and circuits directly involved in this change. Bacteria-plant interactions involve a large number of global regulatory systems, which are essential for protection against new stressful conditions. The interaction of bacteria with
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Lee, Chung, Timothy Kuzel, Richard Meagher, Ximing Yang, Norm Smith, and Qiang Zhang. Preparation for a Clinical Trial Using Adoptive Transfer of Tumor-Reactive TGF_Beta-Insensitive CD8+ T Cells for Treatment of Prostate Cancer. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada462885.

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Lee, Chung. Preparation for a Clinical Trial Using Adoptive Transfer of Tumor-Reactive TGF_Beta-Insensitive CD8+ T Cells for Treatment of Prostate Cancer. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada463479.

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Firon, Nurit, Prem Chourey, Etan Pressman, Allen Hartwell, and Kenneth J. Boote. Molecular Identification and Characterization of Heat-Stress-Responsive Microgametogenesis Genes in Tomato and Sorghum - A Feasibility Study. United States Department of Agriculture, 2007. http://dx.doi.org/10.32747/2007.7591741.bard.

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Exposure to higher than optimal temperatures - heat-stress (HS) - is becoming increasingly common to all crop plants worldwide. Heat stress coinciding with microgametogenesis, especially during the post-meiotic phase that is marked by starch biosynthesis, is often associated with starch-deficient pollen and male sterility and ultimately, greatly reduced crop yields. The molecular basis for the high sensitivity of developing pollen grains, on one hand, and factors involved in pollen heat-tolerance, on the other, is poorly understood. The long-term goal of this project is to provide a better und
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Ficht, Thomas, Gary Splitter, Menachem Banai, and Menachem Davidson. Characterization of B. Melinensis REV 1 Attenuated Mutants. United States Department of Agriculture, 2000. http://dx.doi.org/10.32747/2000.7580667.bard.

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Brucella Mutagenesis (TAMU) The working hypothesis for this study was that survival of Brucella vaccines was directly related to their persistence in the host. This premise is based on previously published work detailing the survival of the currently employed vaccine strains S19 and Rev 1. The approach employed signature-tagged mutagenesis to construct mutants interrupted in individual genes, and the mouse model to identify mutants with attenuated virulence/survival. Intracellular survival in macrophages is the key to both reproductive disease in ruminants and reticuloendothelial disease obser
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