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Academic literature on the topic 'Tablet compression'

Author: Grafiati

Published: 4 June 2021

Last updated: 7 February 2022

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Journal articles on the topic "Tablet compression"

Rajiv Kumar, Kiranjeet Kaur Batth, Jaspreet Kaur, Jaspreet Kaur, Parminder Nain, and R. K. Dhawan. "A most convenient and patient compliance dosage form- Tablet." Journal of Biomedical and Pharmaceutical Research 9, no. 6 (December 17, 2020): 13–19. http://dx.doi.org/10.32553/jbpr.v9i6.815.

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Tablet is defined as solid pharmaceutical dosage form containing drug substance generally with suitable diluents and prepared by either compression which is given as a single unit and are known as solid unit dosage form. Tablets remain popular as a dosage form because of the advantages afforded, both to the manufacturer (e.g. simplicity and economy of the preparation, stability, and convenience in packing, shipping and dispensing) and the patient. The excipients include diluents, Binders and adhesives, disintegrates, etc. Tablets vary in shape and differ greatly in size and weight depending on the amount of the medicinal substance. The ingredients must be granulated prior to compression to assure an even distribution of the active compound in the final tablet. There are two basic techniques which can be used to granulate powders for compressions into a tablet are wet granulation and dry granulation. In this review article tablet manufacturing and evaluation have been discussed. Keywords- Tablet, Granulation, Picking and sticking, Dissolution test, weight variation

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Akhtar, Sabina, and Pulak Dev. "FORMULATION AND EVALUATION OF CHEWABLE MULTIVITAMIN TABLET." International Journal of Current Pharmaceutical Research 9, no. 4 (July 14, 2017): 61. http://dx.doi.org/10.22159/ijcpr.2017v9i4.20958.

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Objective: The overall objective of the present study was to formulate the chewable multivitamin tablet prepared by direct compression method.Methods: The excipient used in this study are mannitol, sucrose, starch, talc, magnesium stearate, vanilla powder for the effective formulation. As it is multivitamin, ascorbic acid, riboflavin, nicotinamide, thiamine HCL are used and evaluated for precompression parameter. The chewable tablets were better presented using sweetener sucrose and vanilla powder as a flavouring agent. The formulated tablet was evaluated for post compression parameter. The chewable tablet are prepared to ensure that they are easily crushed by chewing. The tablet was evaluated for weight variation, hardness, thickness, friability, drug content. Their dissolution properties were assessed using USP (paddle apparatus).Conclusion: From the above study, we conclude that the chewable tablets were prepared by direct compression method and gave the satisfactory and acceptable result. The tablet shows immediate drug release due to direct compressed tabletResults: All the parameter were found within the specification. Drug content of ascorbic acid (103.62%-108.84%), riboflavin (99.88%-112.02%), nicotinamide (93.44%-100.31), thiamine Hcl (105.94%-108.5%) were found.

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Waring, M. J., M. H. Rubinstein, J. W. Forrester, and P. Cole. "ACOUSTIC EMISSION DURING TABLET COMPRESSION." Journal of Pharmacy and Pharmacology 38, S12 (December 1986): 80P. http://dx.doi.org/10.1111/j.2042-7158.1986.tb14309.x.

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Lakio, S., H. Ylinärä, O. Antikainen, H. Räikkönen, and J. Yliruusi. "Spectroscopic insight for tablet compression." European Journal of Pharmaceutics and Biopharmaceutics 90 (February 2015): 16–21. http://dx.doi.org/10.1016/j.ejpb.2014.11.010.

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Sunayana S, Ruchi, Gowda Dv, Vishal Gupta N, Praveen Sivadasu, and Manjunath M. "FORMULATION DEVELOPMENT AND EVALUATION OF ALMOND GUM BASED SUSTAINED RELEASE MATRIX TABLET OF INDOMETHACIN." Asian Journal of Pharmaceutical and Clinical Research 11, no. 12 (December 7, 2018): 166. http://dx.doi.org/10.22159/ajpcr.2018.v11i12.26301.

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Objective: The aspiration of the current research involves employing various concentrations of polymer and filler to develop indomethacin sustained release (SR) matrix tablets. The objective of this research work is to reduce dosing frequency thereby increasing patients compliance and enhanced therapeutic activity.Methods: Polymers such as Almond gum (AG), polyvinylpyrrolidone (PVP), and starch at different concentrations were used for formulating SR polymeric matrix tablets. Evaluation of pre-compression and post-compression parameters was done for both granules and formulated tablets.Results: Results obtained from pre-compression parameters and post-compression parameters suggested that all the parameters are within the prescribed limits, demonstrating that formulated granules had shown better flow properties. The morphological characteristics of the developed tablet were observed by employing scanning electron microscope where the surface of the tablet was found to be smooth from the in vitro dissolution study, combination of AG (30 mg) with PVP (30 mg), and starch used as a filler has sustained the release of drug up to 10 h.Conclusion: Therefore, developed polymeric matrix tablet exhibited enhanced potency over a conventional tablet by exhibiting an excellent dissolution profile for a period of 10 h.

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Rane, Devendra Revanand, Hemant Narhar Gulve, Vikas Vasant Patil, Vinod Madhaorao Thakare, and Vijay Raghunath Patil. "Formulation and evaluation of fast dissolving tablet of albendazole." International Current Pharmaceutical Journal 1, no. 10 (September 5, 2012): 311–16. http://dx.doi.org/10.3329/icpj.v1i10.11848.

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Albendazole is broad spectrum anthelmintic use against many helminths. It is used for treatment of Threadworm, Hookworm, and Tapeworm. It has low bioavailability due to its first pass metabolism. In the present work, fast dissolving tablet of Albendazole was design with a view to and provide a quick onset of action. The main objective of the study was to formulate fast dissolving tablets of Albendazole to achieve a better dissolution rate and further improving the bioavailability of the drug. Fast dissolving tablets prepared by direct compression and using super disintegrants in different concentration and evaluated for the pre-compression parameters. The prepared tablets were evaluated for post compressional evaluation. Among all, the formulation F3 containing 5%w/w superdisintegrant Crospovidone and 20%w/w Microcrystalline Cellulose was considered to be best formulation, which release up to 99.097% in 40 min.DOI: http://dx.doi.org/10.3329/icpj.v1i10.11848 International Current Pharmaceutical Journal 2012, 1(10): 311-316

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Sachan, Anupam Kumar. "Comparative Study of Natural and Synthetic Superdisintegrants in Orodispersible Metformin Tablet." Asian Journal of Pharmaceutical Research and Development 7, no. 3 (June 14, 2019): 46–53. http://dx.doi.org/10.22270/ajprd.v7i3.509.

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Objective: The main objective of this study is comparative study of natural and synthetic superdisintegrants in orodispersible Metformin tablet by using direct compression method and wet granulation method. Method: Orodispersible Metformin tablet were prepared by wet granulation method and direct compression method by using different synthetic and natural superdisintegrants. Orodispersible tablets (ODTs) have received more interest in the pharmaceutical industry for their easy to use and self medication. ODTs overcome the problem of dysphagia (difficulty in swallowing) in the all group age of patients and advantage particularly for the paediatric and geriatric patients. Metformin hydrochloride (Hcl) is an orally administered antihyperglycemic agent, used in the management of non-insulin dependent (type-2) diabetes mellitus. Metformin orodispersible tablet is prepared by using two methods i.e. direct compression method and wet granulation method. Both methods are applied to prepare Orodispersible Metformin tablet. Orodispersible tablet of Metformin was prepared by using superdisintegrants from both natural and synthetic origin. In natural superdisintegrants we used the mucilage of Fenugreek and Lepidium sativum. In synthetic superdisintegrants we used crospovidone and sodium starch glycolate. Conclusion: In direct compression and wet granulation method final blend and granules were evaluated the flow properties like bulk density, tapped density, compressibility index, hausner’s ratio and angle of repose. The values of precompression parameter evaluated were found to be within the prescribed limit and indicated good flow properties. The data obtained from the post compression methods was studied. Other parameters such as wetting time, water absorption ratio were also evaluated. The formulation (F5) containing 10% crospovidone prepared by wet granulation method was found the optimize formulation. Keywords: Metformin Hcl, Orodispersible tablets, Superdisintegrants, Direct Compression, and Wet granulation Objective: The main objective of this study is comparative study of natural and synthetic superdisintegrants in orodispersible Metformin tablet by using direct compression method and wet granulation method. Method: Orodispersible Metformin tablet were prepared by wet granulation method and direct compression method by using different synthetic and natural superdisintegrants. Orodispersible tablets (ODTs) have received more interest in the pharmaceutical industry for their easy to use and self medication. ODTs overcome the problem of dysphagia (difficulty in swallowing) in the all group age of patients and advantage particularly for the paediatric and geriatric patients. Metformin hydrochloride (Hcl) is an orally administered antihyperglycemic agent, used in the management of non-insulin dependent (type-2) diabetes mellitus. Metformin orodispersible tablet is prepared by using two methods i.e. direct compression method and wet granulation method. Both methods are applied to prepare Orodispersible Metformin tablet. Orodispersible tablet of Metformin was prepared by using superdisintegrants from both natural and synthetic origin. In natural superdisintegrants we used the mucilage of Fenugreek and Lepidium sativum. In synthetic superdisintegrants we used crospovidone and sodium starch glycolate. Conclusion: In direct compression and wet granulation method final blend and granules were evaluated the flow properties like bulk density, tapped density, compressibility index, hausner’s ratio and angle of repose. The values of precompression parameter evaluated were found to be within the prescribed limit and indicated good flow properties. The data obtained from the post compression methods was studied. Other parameters such as wetting time, water absorption ratio were also evaluated. The formulation (F5) containing 10% crospovidone prepared by wet granulation method was found the optimize formulation. Keywords:

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Badawi, Aliaa A., Mahmoud M. Hegazy, Dina Louis, and Mohammed A. Eldegwy. "Solving manufacturing problems for L-carnitine-L-tartrate to improve the likelihood of successful product scale-up." Acta Pharmaceutica 67, no. 4 (December 20, 2017): 511–25. http://dx.doi.org/10.1515/acph-2017-0033.

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AbstractL-carnitine-L-tartrate, a non-essential amino acid, is hygroscopic. This causes a problem in tablet production due to pronounced adhesion of tablets to punches. A 33 full factorial design was adopted to suggest a tablet formulation. Three adsorbents were suggested (Aerosil 200, Aerosil R972, talc) to reduce stickiness at three concentrations (1, 3 and 5 %), and three fillers (mannitol, Avicel PH 101, Dibasic calcium phosphate) were chosen to prepare 27 formulations. Micromeritic properties of formulations were studied, and tablets were prepared by wet granulation. Absence of picking, sticking or capping, recording of sufficient hardness, acceptable friability and tablet ejection force indicated formulation success. The resulting formulation prepared using Avicel PH 101 and 1 % Aerosil 200 was submitted to further investigation in order to choose the most suitable compression conditions using a 33full factorial design. Variables included compression force, tableting rate and magnesium stearate (lubricant) concentration. The formulation prepared at compression force of 25 kN, using 2 % magnesium stearate, at a production rate of 30 tablets/ minute, was found to be the most appropriate scale up candidate.

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Parfati, Nani, Karina Citra Rani, and Meilany Meilany. "THE EFFECT OF COPROCESSED SUPERDISINTEGRANTS RATIO (CROSPOVIDONE-SODIUM STARCH GLYCOLATE) TO THE PHYSICOCHEMICAL CHARACTERISTICS OF ATENOLOL ORALLY DISINTEGRATING TABLETS." Asian Journal of Pharmaceutical and Clinical Research 11, no. 2 (February 1, 2018): 318. http://dx.doi.org/10.22159/ajpcr.2018.v11i2.23010.

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Objective: The objective of this study was to evaluate the effect of coprocessed superdisintegrants (crospovidone-sodium starch glycolate) ratio 1:1; 1:2; and 1:3 to the physicochemical characteristics of atenolol orally disintegrating tablets.Methods: Orally disintegrating tablets of atenolol were prepared by direct compression method. There were three formulas which using three different ratios of coprocessed superdisintegrants (crospovidone-sodium starch glycolate). The ratio of coprocessed superdisintegrants were, 1:1 (formula 1); 1:2 (formula 2); and 1:3 (formula 3). Evaluation of the formulas was conducted before compression (pre-compression evaluation) and after compression (post-compression evaluation).Results: The results of pre-compression evaluation showed that all the formulas have good flowability and excellent angle of repose. The results of post-compression evaluation showed that all the formulas met the specification of orally disintegrating tablets. The different ratio of coprocessed crospovidone-sodium starch glycolate (1:1; 1:2; and 1:3) caused significant differences in tablet dispersion time (p<0.05). Dissolution test showed that all the formulas met the specification of dissolution from atenolol tablet (not <85% of atenolol was dissolved in 30 min). Formula 1 showed the highest dissolution efficiency (92.91±0.11)% and area under the curve value (11149.13±13.15) compared to formula 2 and formula 3.Conclusion: The results from this study showed that coprocessed superdisintegrants (crospovidone-sodium starch glycolate) ratio affect the physicochemical characteristics of atenolol orally disintegrating tablet. Based on pre-compression evaluation and post-compression evaluation, formula 1 was the best formula.

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Franc, Aleš, Slavomir Kurhajec, Sylvie Pavloková, Dana Sabadková, and Jan Muselík. "Influence of concentration and type of microcrystalline cellulose on the physical properties of tablets containing Cornelian cherry fruits." Acta Pharmaceutica 67, no. 2 (June 27, 2017): 187–202. http://dx.doi.org/10.1515/acph-2017-0019.

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AbstractThe aim of this study was to find the optimal tablet composition with maximum content of dried fruits (Cornus mas L.). The effect of three different concentrations (12.5, 25 and 50 %) of two types of microcrystalline cellulose (Avicel®PH 101 and Avicel®PH 200) and three different compression pressures (20, 60 and 100 MPa) on the physical properties of tablet blends and tablets was studied. Tablets containing 50 % Avicel®PH 101 compressed under 100 MPa were found to have the best physical properties. This combination of composition and compression pressure resulted in stable tablets even after storage under accelerated stability conditions (6 months, 40 °C and 75 % RH).

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Dissertations / Theses on the topic "Tablet compression"

Govan, Otesh Thakorlal. "Time dependent effects in powder compression." Thesis, Cardiff University, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.314682.

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Blundell, L. P. "Characterisation and compaction parameters of directly compressible tablet excipients." Thesis, Cardiff University, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.356740.

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Larhrib, El Hassane. "Characterisation & compaction of polyethylene glycols." Thesis, Liverpool John Moores University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242150.

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Yelamanchili, Satish Neau Steven H. "Colon specific delivery using ethylcellulose and chitosan in a compression coated tablet." Diss., UMK access, 2006.

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Thesis (M.S.)--School of Pharmacy. University of Missouri--Kansas City, 2006.
"A thesis in pharmaceutical science." Typescript. Advisor: Steven H. Neau. Vita. Title from "catalog record" of the print edition Description based on contents viewed Nov. 12, 2007. Includes bibliographical references (leaves 82-87). Online version of the print edition.

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Gabrielsson, Jon. "Multivariate methods in tablet formulation." Doctoral thesis, Umeå : Univ, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-268.

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Persson, Ann-Sofie. "Flow and Compression of Granulated Powders : The Accuracy of Discrete Element Simulations and Assessment of Tablet Microstructure." Doctoral thesis, Uppsala universitet, Institutionen för farmaci, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-208808.

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Simulations are powerful and important tools for gaining insight into powder processes. Ultimately, simulations have the potential to replace experiments. Thus, accurate models and insight into the essential factors for descriptions of powder behaviour are required. In this thesis, discrete element method (DEM) simulations of granule flow and compression were evaluated to deduce parameters and potential models essential for the experimental and numerical correspondence. In addition, the evolution in tablet microstructure during compression was studied using mercury porosimetry. Granule flow was measured using angle of repose, discharge rate, and shear. The granular flow depended primarily on particle shape and surface texture due to the mutual influence of these two parameters on the inter-particle forces. Rolling friction stabilised both the heap formation and promoted shear in the elastic quasi-static flow regime. Thus, rolling friction was established to be an essential simulation parameter for the correspondence to experiments. Current compression models often neglect the elastic compact deformation during particle loading. In this thesis, two fundamentally different models were evaluated with focus of including the elastic deformation. The first model comprised a maximal particle overlap, where elastic deformation commences. The second model accounted for the contact dependence and impingement at high relative densities. This model was based on a truncated-sphere followed by a Voronoi extension. The validity of the models was demonstrated by the elastic qualitative correspondence to experimental compressions for ductile materials. In tablets, the void (inter-granular pore) diameter was dependent on the degree of compression. Thus, the degree of compression provides an indication of the tablet microstructure. The microstructure was subsequently observed to be related to the tablet tensile strength as inferred from a percolation threshold required for formation of coherent tablets. In summary, this thesis has shed light onto the potential of simulating flow and compression of granulated pharmaceutical powders using DEM. Continuous work in the area are required to further improve the models to increase the experimental and numerical correspondence.

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Mahmoodi, Foad. "Compression Mechanics of Powders and Granular Materials Probed by Force Distributions and a Micromechanically Based Compaction Equation." Doctoral thesis, Uppsala universitet, Institutionen för farmaci, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-171874.

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The internal dynamics of powder systems under compression are as of yet not fully understood, and thus there is a necessity for approaches that can help in further clarifying and enhancing the level of understanding on this subject. To this end, the internal dynamics of powder systems under compression were probed by means of force distributions and a novel compaction equation. The determination of force distributions hinged on the use of carbon paper as a force sensor, where the imprints transferred from it onto white paper where converted through calibration into forces. Through analysis of these imprints, it was found that the absence of friction and bonding capacity between the particles composing the powder bed had no effect on how the applied load was transferred through the system. Additionally, it was found that pellet strength had a role to play in the homogeneity of force distributions, where, upon the occurrence of fracture, force distributions became less homogenous. A novel compaction equation was derived and tested on a series of systems composed of pellets with differing mechanical properties. The main value of the equation lay in its ability to predict compression behavior from single particle properties, and the agreement was especially good when a compact of zero porosity was formed. The utility of the equation was tested in two further studies, using a series of pharmaceutically relevant powder materials. It was established that the A parameter of the equation was a measure of the deformability of the powder material, much like the Heckel 1/K parameter, and can be used as a means to rank powders according to deformability, i.e. to establish plasticity scale. The equation also provided insights into the dominating compression mechanisms through an invariance that could be exploited to determine the point, at which the powder system became constrained, i.e. the end of rearrangement. Additionally, the robustness of the equation was demonstrated through fruitful analysis of a set of diverse materials. In summary, this thesis has provided insights and tools that can be translated into more efficient development and manufacturing of medicines in the form of tablets.

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Tunón, Åsa. "Preparation of Tablets from Reservoir Pellets with an Emphasis on the Compression Behaviour and Drug Release." Doctoral thesis, Uppsala University, Department of Pharmacy, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3411.

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The preparation of multiple unit tablets was investigated in this thesis with the intention of gaining a deeper understanding of some of the factors that influence the properties of such tablets.

Initially, three different types of pellets (drug, soft and disintegrant pellets) were combined as a model to investigate the ability of the mixture to form disintegrating tablets. The proportions of the different pellets and the type of disintegrant used were factors that independently influenced the tablet properties. Furthermore, the properties of tablets containing drug pellets barrier-coated with an aqueous polymer dispersion were also found to depend on the coating thickness and the compaction pressure.

When compacting pellets barrier-coated with a solvent-based polymer solution without incorporating excipient particles in the tablet formulation, a high pellet porosity was advantageous to preserve the original drug release profile, even though highly porous pellets became more densified and deformed than pellets of lower porosity.

The influence of the properties of excipient particles on the deformation of the reservoir pellets was also studied and, although the amount of flattening of the pellets was only slightly affected, changes in the pellet shape (irregularity) with alterations in the porosity and size of the excipient particles were more substantial. In contrast, the properties of the excipient particles did not affect the pellet densification.

The solvent-based coating used was able to adapt to the changes in volume and shape that the pellets underwent during compaction. The coating structure appears to be changed by compaction and it is proposed that the final structure of the coating is the net effect of two parallel processes, one reducing and one prolonging the transport time of the drug across the coating. Thus, the drug release could be maintained or even prolonged after compaction, despite extensive structural changes of the reservoir pellets.

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Alanezi, Abdulkareem Ali. "Development of an Orally Disintegrating Mini-Tablet (ODMTs) Containing Metoclopramide HCl to Enhance Patient Compliance." University of Toledo Health Science Campus / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=mco1417861431.

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Spaniol, Bárbara. "Comparação do comportamento compressional de granulado contendo produto seco por aspersão de phyllanthus niruri l. entre máquinas de comprimir alternativa e rotativa." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2007. http://hdl.handle.net/10183/11062.

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Este trabalho foi realizado com a finalidade de avaliar o comportamento compressional de granulado contendo alta concentração de produto seco por aspersão de Phyllanthus niruri em máquinas de comprimir alternativa (MCA) e rotativa (MCR). A partir do material vegetal de P. niruri foram produzidas a solução extrativa e o produto seco por aspersão (PSA). A formulação dos comprimidos foi composta de granulados do PSA (GPSA) (92 %), adjuvantes granulados (GADJ) (7,92 %) e estearato de magnésio (0,08 %). O GPSA foi produzido por granulação por via seca e o GADJ, composto de celulose microcristalina (62,9 %) e amidoglicolato de sódio (37,1 %), por via úmida. A granulometria do complexo farmacêutico (CF) compreendeu a faixa de 0,250 a 0,850 mm. Foram produzidos comprimidos em máquina universal de ensaios, em punções planos com diâmetro de 13 e 5 mm, avaliando-se a influência da altura da coluna de CF e do diâmetro da matriz sobre as características dos compactos obtidos. A previsão da resistência à tensão e expansão volumétrica radial se torna impossibilitada pela suas dependências das variáveis aplicadas. Dos compactos obtidos em matriz de 13 mm, produzidos com sete forças de compressão (de 2,26 a 16,04 kN), verificou-se a linearidade entre a força de compressão e a resistência à tensão dos compactos. Além disso, em diferentes pressões de compressão, que variaram de 13,2 a 120,9 MPa, avaliou-se, através do modelo de Heckel (método out die), o mecanismo de consolidação do complexo farmacêutico, que apresentou comportamento fragmentativo em baixas pressões e deformação plástica a partir de 30,2 MPa. O valor de pressão média por deformação (Py) foi igual a 229,01 MPa, indicativo de que as condições da granulação por via seca podem ter influenciado as características de consolidação do complexo farmacêutico. O CF não apresentou defeitos de compressão, como laminação e descabeçamento, nem variação de peso em ambos os modelos de máquinas de comprimir utilizados. Imagens das faces superior e inferior dos comprimidos obtidos na MCA e MCR, tratadas com programa de análise de imagens, esclareceram de forma quantitativa as diferenças entre elas, sugerindo a ocorrência de fenômeno de percolação. As diferentes velocidades de produção em MCR evidenciaram o comportamento visco-plástico do CF, pois em menores velocidades houve aumento significativo da resistência à tensão dos comprimidos, não afetando, no entanto, o tempo de desintegração dos mesmos. Comprimidos produzidos em MCR apresentaram menor friabilidade e porosidade, que não se refletiu em resistência à tensão àquela apresentada para os obtidos em MCA. A cedência do PSA não sofreu influência do tipo de equipamento ou das condições experimentais na quais os comprimidos foram produzidos. As diferenças na construção e funcionamento dos dois tipos de máquinas de comprimir foram influentes sobre o produto final, já que comprimidos, com resistências à tensão semelhantes, advindos de máquinas de comprimir distintas, apresentaram diferenças nos parâmetros de qualidade avaliados.
This work was carried out to evaluate the compressional behavior of granules containing high load of a Phyllanthus niruri spray-dried extract in eccentric (ETM) and rotary (RTM) tablet presses. Extractive solution and spray-dried extract (SDE) were produced from the plant aerial parts. Tablets were constituted by SDE granules (SDEG) (92 %), excipients granules (EXCG) (7.92 %) and magnesium stearate (0.08 %). SDEG was obtained by dry granulation and EXCG, composed by microcrystalline cellulose (62.9 %) and sodium starch glycolate (37.1 %), by wet granulation. Particle size distribution was fixed between 0.355 to 0.850 mm. Tablets were also produced in a universal assay machine with flat-faced punches of 10 and 5 mm diameter, in order to estimate the influence of granules bed height and tooling diameter on the compact characteristics. Tensile strength and radial elastic recovery demonstrated to be very dependent of both variables hindering further correlations. For the tablets produced in 13 mm tooling by applying seven compression forces (from 2.26 to 16.06 kN), linearity between compression force and tensile strength was observed. The consolidation mechanism of the granule mixture could be elucidated using different compression pressures, in the range from 13.2 to 120.9 MPa. Heckel’s model (out die method) pointed out the occurrence of brittle behavior under low pressures and plastic deformation beginning at 30.2 MPa. Mean yield pressure (Py) was 229.01 MPa, indicating that dry granulation conditions may have influenced the consolidation characteristics of the formulation. Tablets did not evidence any mechanical failures, such as lamination or capping, or anomalous weight variation in both tablet machine types. Upper and lower tablet surfaces images from ETM and RTM, analyzed by an image-analysis-software, showed differences between the granules distribution, suggesting the occurrence of percolation phenomenon. Different RTM speeds suggested the visco-plastic behavior of the formulation, since by slower rotation speeds tablet’s tensile strength significantly increases, but the disintegration time was not affected. Tablets produced in RTM showed lower friability and porosity, which did not reflect on higher tensile strength, than those obtained by tablets of ETM. SDE release was not influenced by the type of equipment or operational conditions to which the compacts were submitted. Construction and operation differences between both tablet presses influenced the final product, since tablets with similar tensile strength, produced by distinct tablet machines, exhibited different quality parameters.

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Books on the topic "Tablet compression"

Altaf, Syed Azhar. Tablet machine instrumentation to study tablet compaction and compression of polymer-coated beads into tablets. 1995.

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Jaber, Ahmad Kh Bani. Formulation and in vitro-in vivo evaluation of a new compression-coated tablet of amoxicillin/clavulanate and formulation potential of the antimicrobial peptide nisin. 1998.

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Jaber, Ahmad Kh Bani. Formulation and in vitro-in vivo evaluation of a new compression-coated tablet of amoxicillin/clavulanate and formulation potential of the antimicrobial peptide nisin. 1998.

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Wilson, Mark. Pragmatics’ Place at the Table. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198803478.003.0001.

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Physical events that transpire across many size scales require significant data compression for their successful handling. A popular remedy practiced within modern multiscalar methods breaks a descriptive task into sub-problems focused upon dominant behaviors that arise on different length scales. Each localized form of description employs the same language in different ways. This contextualization requires that these localized veins of description share data with one another in non-standard ways. We employ allied techniques in everyday life as well and philosophical confusions arise when the underlying strategic architecture is not properly recognized. Nine general morals concerning language usage are abstracted from this examination.

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Byrd, Alan K. Transonic compressor blade tip flow visualization on a water table. 1986.

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Anderson, James A. Brain Theory. Oxford University Press, 2018. http://dx.doi.org/10.1093/acprof:oso/9780199357789.003.0013.

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The elementary particles of cognition are concepts. Simple, accurate association alone can be misleading. Cognitive concepts work as valuable cognitive data compression, for example, giving a set of related items the same class name: tables, chairs, birds. Cognitive concepts also contain internal structure with good and bad examples and have fuzzy edges. Concepts can be associatively linked in semantic networks to store and retrieve information. Cognition using networks is an active search process and need not require further learning to be useful. Low-level concepts can lead to the formation of higher level abstractions. An experiment by Deidre Gentner involves perception of identity in pairs of items; some pairs the same and some not. Seeing many identical pairs allows the abstraction of “identity.” The abstract relationship “identity” can then become more powerful than the details of any single example pair.

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Dourish, Paul. Protocols, Packets, and Proximity. University of Illinois Press, 2017. http://dx.doi.org/10.5406/illinois/9780252039362.003.0008.

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This chapter analyzes the materialities of Internet protocols, focusing on the relationship between content and conduit, which involves both the compression and modulation of signals. Network protocols are shaped by material constraints. Similarly, the centrality of routing to the Internet can be understood materially in terms of the arrangement of network nodes, the cost of routing, the structure of networks, the size of routing tables, and the dynamics of connectivity. Critically, this materiality cuts across apparently different domains of concern—from the practice of network operations to the rhetoric of democratic access. The chapter then contrasts two different protocols, the Routing Information Protocol and the Exterior Gateway Protocol, which emerged in different historical moments and cultural conditions. Examining the social construction of these network protocols can help differentiate the actual Internet from a possible or imagined Internet.

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Diagnosis and Treatment of Worker-Related Musculoskeletal Disorders of the Upper Extremity (Evidence Report/Technology Assessment,). Agency for Healthcare Research and Quality, 2003.

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Levy, David M., and Ieva Saule. General anaesthesia for caesarean delivery. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198713333.003.0022.

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General anaesthesia (GA) is most often indicated for category 1 (immediate threat to life of mother or baby) caesarean delivery (CD) or when neuraxial anaesthesia has failed or is contraindicated. Secure intravenous access is essential. Jugular venous cannulation (with ultrasound guidance) is required if peripheral access is inadequate. A World Health Organization surgical safety checklist must be used. The shoulders and upper back should be ramped. Left lateral table tilt or other means of uterine displacement are essential to minimize aortocaval compression, and a head-up position is recommended to improve the efficiency of preoxygenation and reduce the likelihood of gastric contents reaching the oropharynx. Cricoid pressure is controversial. In the United Kingdom, thiopental remains the induction agent of choice, although there is scant evidence upon which to avoid propofol. In pre-eclampsia, it is essential to obtund the pressor response to laryngoscopy with remifentanil or alfentanil. Rocuronium is an acceptable alternative to succinylcholine for neuromuscular blockade. Sugammadex offers the possibility of swifter reversal of rocuronium than spontaneous recovery from succinylcholine. Management of difficult tracheal intubation is focused on ‘oxygenation without aspiration’ and prevention of airway trauma. The Classic™ laryngeal mask airway is the most commonly used rescue airway in the United Kingdom. There is a large set of data from fasted women of low body mass index who have undergone elective CD safely with a Proseal™ or Supreme™ laryngeal mask airway. Sevoflurane is the most popular volatile agent for maintenance of GA. The role of electroencephalography-based depth of anaesthesia monitors at CD remains to be established. Intraoperative end-tidal carbon dioxide tension should be maintained below 4.0 kPa.

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Brine, Kelly Gordon. The Art of Cinematic Storytelling. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780190054328.001.0001.

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The Art of Cinematic Storytelling: A Visual Guide to Planning Shots, Cuts, and Transitions is a practical introduction to the design of shots, cuts, and transitions for film, video, television, animation, and game design. The author-illustrator is a storyboard artist who has worked with and learned from over 200 professional directors and cinematographers. This book’s clear and concise explanations and vivid examples demystify the visual design choices that are fundamental to directing and editing. Hundreds of illustrations and diagrams support the text. The primary emphasis is on blocking actors and positioning the camera for mood, meaning, and continuity editing. This book delves deeply into controlling the audience’s understanding and perception of time and space; designing in-camera time transitions; compressing and expanding time; composing creative shots for cinematic storytelling; choosing between objective and subjective storytelling; motivating camera moves; choosing lenses; using screen geography and film grammar for clarity; planning shots with continuity editing in mind; knowing how and when to cut; beginning and ending scenes; and using storyboards for planning and communication. Several chapters are devoted to how to block and shoot action involving travel, pursuits, searches, dialogue, groups, and driving. While the approach is based largely on well-established techniques of cinematography and continuity editing, attention is also given to jump cuts, tableau shots, and unconventional framing. The topics are covered thoroughly and systematically, and this book serves both as an introductory text and as a reference work for more advanced students of film.

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Book chapters on the topic "Tablet compression"

Buchsbaum, Adam L., and Raffaele Giancarlo. "Table Compression." In Encyclopedia of Algorithms, 939–42. Boston, MA: Springer US, 2008. http://dx.doi.org/10.1007/978-0-387-30162-4_418.

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Giancarlo, Raffaele, and Adam L. Buchsbaum. "Table Compression." In Encyclopedia of Algorithms, 2193–98. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-2864-4_418.

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Giancarlo, Raffaele, and Adam L.Buchsbaum. "Table Compression." In Encyclopedia of Algorithms, 1–7. Boston, MA: Springer US, 2014. http://dx.doi.org/10.1007/978-3-642-27848-8_418-2.

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Mielikainen, Jarno. "Lookup-Table Based Hyperspectral Data Compression." In Satellite Data Compression, 169–84. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4614-1183-3_8.

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Driesen, Karel. "Row Displacement Compression of Message Dispatch Tables." In Efficient Polymorphic Calls, 33–53. Boston, MA: Springer US, 2001. http://dx.doi.org/10.1007/978-1-4615-1681-1_4.

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Vivek, Srinivas. "Revisiting a Masked Lookup-Table Compression Scheme." In Lecture Notes in Computer Science, 369–83. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-71667-1_19.

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Gharbi, Nebras, Fred Hemery, Christophe Lecoutre, and Olivier Roussel. "Sliced Table Constraints: Combining Compression and Tabular Reduction." In Integration of AI and OR Techniques in Constraint Programming, 120–35. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-07046-9_9.

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Liu, Yanbing, Yifu Yang, Ping Liu, and Jianlong Tan. "A Table Compression Method for Extended Aho-Corasick Automaton." In Implementation and Application of Automata, 84–93. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-02979-0_12.

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Hyyrö, Heikki, and Shunsuke Inenaga. "Compacting a Dynamic Edit Distance Table by RLE Compression." In Lecture Notes in Computer Science, 302–13. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-49192-8_25.

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Zheng, Jack Y., and Robert L. Ternik. "Development of Low-Dose Solid Oral Tablets Using Direct Compression." In Formulation and Analytical Development for Low-Dose Oral Drug Products, 159–204. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470386361.ch7.

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Conference papers on the topic "Tablet compression"

Ishigami, Fumiya, Koichi Nagata, Masaya Ohta, and Katsumi Yamashita. "Data compression for photo-based augmented reality on a tablet." In 2016 IEEE 5th Global Conference on Consumer Electronics. IEEE, 2016. http://dx.doi.org/10.1109/gcce.2016.7800480.

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"Table of Contents." In Data Compression Conference. IEEE, 2005. http://dx.doi.org/10.1109/dcc.2005.84.

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"Table of Contents." In 2010 Data Compression Conference. IEEE, 2010. http://dx.doi.org/10.1109/dcc.2010.4.

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"Table of Contents." In 2009 Data Compression Conference. IEEE, 2009. http://dx.doi.org/10.1109/dcc.2009.4.

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Le Charlier, Baudouin, Minh Thanh Khong, Christophe Lecoutre, and Yves Deville. "Automatic Synthesis of Smart Table Constraints by Abstraction of Table Constraints." In Twenty-Sixth International Joint Conference on Artificial Intelligence. California: International Joint Conferences on Artificial Intelligence Organization, 2017. http://dx.doi.org/10.24963/ijcai.2017/95.

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The smart table constraint represents a powerful modeling tool that has been recently introduced. This constraint allows the user to represent compactly a number of well-known (global) constraints and more generally any arbitrarily structured constraints, especially when disjunction is at stake. In many problems, some constraints are given under the basic and simple form of tables explicitly listing the allowed combinations of values. In this paper, we propose an algorithm to convert automatically any (ordinary) table into a compact smart table. Its theoretical time complexity is shown to be quadratic in the size of the input table. Experimental results demonstrate its compression efficiency on many constraint cases while showing its reasonable execution time. It is then shown that using filtering algorithms on the resulting smart table is more efficient than using state of the art filtering algorithms on the initial table.

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"Table of contents." In 2013 Data Compression Conference (DCC). IEEE, 2013. http://dx.doi.org/10.1109/dcc.2013.4.

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"Table of Contents." In Data Compression Conference (dcc 2008). IEEE, 2008. http://dx.doi.org/10.1109/dcc.2008.5.

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"Table of Contents." In 2011 Data Compression Conference (DCC). IEEE, 2011. http://dx.doi.org/10.1109/dcc.2011.4.

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"Table of Contents." In 2019 Data Compression Conference (DCC). IEEE, 2019. http://dx.doi.org/10.1109/dcc.2019.00007.

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"Table of Contents." In 2020 Data Compression Conference (DCC). IEEE, 2020. http://dx.doi.org/10.1109/dcc47342.2020.00007.

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Reports on the topic "Tablet compression"

AWARE INC CAMBRIDGE MA. The Performance of Wavelets for Data Compression in Selected Military Applications. Volume 2. Supplementary Tables and Graphs. Fort Belvoir, VA: Defense Technical Information Center, January 1990. http://dx.doi.org/10.21236/ada219231.

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Ley, M., Zane Lloyd, Shinhyu Kang, and Dan Cook. Concrete Pavement Mixtures with High Supplementary Cementitious Materials Content: Volume 3. Illinois Center for Transportation, September 2021. http://dx.doi.org/10.36501/0197-9191/21-032.

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Fly ash is a by-product of coal combustion, made up of particles that are collected through various methods. This by-product has been used successfully as a partial Portland cement replacement in concrete, but the performance predictions of fly ash in concrete have been difficult to predict, especially at high fly ash replacement rates. This study focuses on comparing the performance of concrete with a variety of fly ash mixtures as well as the particle distribution and chemical makeup of fly ash. The slump, unit weight, compressive strength, and isothermal calorimetry tests were used to measure the performance of concrete at 0%, 20%, and 40% fly ash replacement levels. The particle distribution of fly ash was measured with an automated scanning electron microscope. Additionally, the major and minor oxides from the chemical makeup of fly ash were measured for each mixture and inputted into a table. The particle distribution and chemical makeup of fly ash were compared to the performance of slump, unit weight, compressive strength, isothermal calorimetry, and surface electrical resistivity.

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