Academic literature on the topic 'Tablet hardness'

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Journal articles on the topic "Tablet hardness"

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Wang, Yifei, Zhisheng Wu, Zhaoyi Wang, Manfei Xu, Xinyuan Shi, and Yanjiang Qiao. "Rapid analysis of spatial distribution of PVPP and hardness of Yinhuang dispersible tablets by NIR-CI." Journal of Innovative Optical Health Sciences 09, no. 02 (2016): 1550016. http://dx.doi.org/10.1142/s1793545815500169.

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The present study aimed at investigating the relationship between tablet hardness and homogeneity of different Yinhuang dispersible tablets by near-infrared chemical imaging (NIR-CI) technology. The regularity of best hardness was founded between tablet hardness and the spatial distribution uniformity of Yinhuang dispersible tablets. The ingredients homogeneity of Yinhuang dispersible tablets could be spatially determined using basic analysis of correlation between analysis (BACRA) method and binary image. Then different hardnesses of Yinhuang dispersible tablets were measured. Finally, the re
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Rosaini, Henni, Rina Wahyuni, Addina Zafrul, and Ela Indah Sari. "FORMULATION AND CHARACTERIZATION OF TABLETS FROM SIMPLICIA AND EXTRACT OF SUNGKAI’S (Peronema canescens Jack) LEAF." International Journal of Pharmaceutical Sciences and Medicine 8, no. 10 (2023): 65–75. http://dx.doi.org/10.47760/ijpsm.2023.v08i10.006.

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Tablets are solid preparations containing medicinal ingredients with or without excipients, usually consisting of one or more active substances. Preparations in tablet form have the best mechanical, chemical, and microbiological stability compared to liquid dosage forms, so they are more resistant to physical damage. This study aims to formulation and characterization of tablet from simplicia and dried extract of sungkai’s (Peronema canescens Jack) leaf by wet granulation which consisted of three formulas, namely F1 without active substances, F2 active substances from sungkai’s leaf simplicia,
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Luke, Stefani, Martha Ervina, and Lannie Hadisoewignyo. "Optimization of Coating Formula of White Pomegranate Peel Extract (Punica granatum L.) Film Coated Tablet Using Kollicoat Protect." Indonesian Journal of Pharmaceutical Research 1, no. 1 (2021): 19–27. http://dx.doi.org/10.31869/ijpr.v1i1.1993.

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White pomegranate peel has many kinds uses, one of them as antimalaria. The unpleasant appearance and bitter taste of white pomegranate peel tablet can be covered by film coated using Kollicoat Protect. This research aimed to determine the effect of concentration and type of solvent used as a coating on the physical properties of the coated tablets and determine the optimum formula. Tablets were made using direct compression method and then coated using Kollicoat Protect. The optimization of coating formula was performed using a factorial design with design expert software ver 10.0. Responses
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Sari, Rodiah Nurbaya, Hari Eko Irianto, and Ema Hastarini. "Production of Unsaturated Fatty Acids Concentrate Tablets from Sardinella sp. Oil." E3S Web of Conferences 147 (2020): 03008. http://dx.doi.org/10.1051/e3sconf/202014703008.

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Tablets are medicinal ingredients in solid dosage forms which are usually prepared with suitable pharmaceutical ingredients. In this study, unsaturated fatty acids concentrate from Sardinella sp. oil was used as raw material and then it was microencapsulated. The microcapsule was formulated into a tablet with proportion of 250 mg concentrated unsaturated fatty acids for each 450 mg tablet. Tablet granules were analyzed for compressibility, flow rate, and fixed angle. While, the tablets were determined for weight uniformity, released time, hardness, and tablet size uniformity. The results showe
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Dadang Putra Mardigantara, Mikhania C. E. ,. Dewi rashati,. "PERBANDINGAN SIFAT FISIK TABLET SALUT CIPROFLOXACIN 500 MG MEREK GENERIK DAN MEREK DAGANG." JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 1, no. 1 (2021): 7–12. http://dx.doi.org/10.53864/jifakfar.v1i1.5.

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The aim of this study was to compare physical properties ciprofloxacin 500 mg coated tablet generic and trademark brand. The test include weight uniformity, tablet hardness, tablet friability, and disintegration time test. Descriptive experimental design (the one-shot case study) was used as study design. Samples were taken from three generic brands and three trademarks brand ciprofloxacin 500 mg coated tablets. Samples were produced by different factories and taken by simple random sampling method. The results showed that ciprofloxacin 500 mg coated tablets generic and trademark brand are com
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Chongcherdsak, Noppadol, Chutima Limmatvapirat, and Sontaya Limmatvapirat. "Factors Affecting Design of Shellac-Based Matrix Tablet through Annealing Process." Advanced Materials Research 506 (April 2012): 421–24. http://dx.doi.org/10.4028/www.scientific.net/amr.506.421.

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The aim of research was to elucidate effect of annealing temperature and shellac (SHL) content on properties of shellac-based matrix tablets. Theophylline was selected as a model drug. The tablets were prepared by direct compression process and then annealed at various temperatures for 24 hours. The tablet properties, including hardness and disintegration time were comparatively. The result demonstrated that annealing temperature directly affected the hardness and disintegration time of tablets. At 60oC or more, the hardness was increased more than 1.5 times as compared to that of un-annealed
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Kuwata, Aya, Agata Ishikawa, Tetsuo Ono, and Etsuo Yonemochi. "Granulation Methods and the Mechanisms for Improving Hardness of Loxoprofen Sodium Hydrate-Containing Tablets." Pharmaceutics 17, no. 4 (2025): 455. https://doi.org/10.3390/pharmaceutics17040455.

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Objectives: We investigated the compression mechanisms for loxoprofen sodium (LXP), which is known to occur as a dihydrate, and identified parameters that influence the tablet hardness of LXP tablets prepared by the wet granulation method. Method: LXP granules were prepared with water or ethanol as the solvent, dried under various conditions and sieved for particle size control, with 1% Mg-st added before tablet compression. Results: The findings indicated that both the granulation solvent and drying temperature significantly impacted the tablet hardness. Granules prepared with ethanol exhibit
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Sipos, Emese, Andrea Ramona Oltean, Zoltán-István Szabó, Emőke-Margit Rédai, and Gabriella Dónáth Nagy. "Application of SeDeM expert systems in preformulation studies of pediatric ibuprofen ODT tablets." Acta Pharmaceutica 67, no. 2 (2017): 237–46. http://dx.doi.org/10.1515/acph-2017-0017.

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Abstract Pediatric, ibuprofen containing orodispersible tablets (ODTs) were prepared using the SeDeM expert system methodology. In order to facilitate formulation, directly compressible ibuprofen was employed (Ibuprofen DC 8TM) and characterized using its SeDeM profile. The mannitol based superdisintegrant Ludiflash® was characterized by the SeDeM-ODT expert system, which also allowed calculation of the optimal excipient concentration in order to obtain suitable tablet hardness and disintegration time. After adding a sweetener and a standard combination of lubricants, the optimized formulation
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Muhammad Rezky Wahyudi, Yumna Zaida, Fiona Maulidia, Regina Nabila, Della Puspita, and Nor Latifah. "Pengaruh Variasi Bahan Pengikat Alami dan Sintetis terhadap Kekerasan dan Kerapuhan Tablet." An-Najat 2, no. 4 (2024): 246–57. https://doi.org/10.59841/an-najat.v2i4.1955.

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Tablets are one of the most widely used pharmaceutical forms due to their practicality and cost-effectiveness. In the tablet formulation process, binders play an important role in ensuring appropriate hardness and friability, which are crucial in maintaining the physical quality of the tablet. This study aims to compare the effectiveness of natural and synthetic binders in enhancing tablet hardness and reducing friability. The method used is a literature review from various scientific sources. The results show that natural binders, such as starch and gelatin, can increase tablet hardness and r
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Sinaga, Alex Handani, and Novicha Aulya Fendri. "Addition Of Various Concentrations Of Gadung Tuber Starch Which Is Determined As A Binder To The Physical Properties Of Mefanamic Acid Tablets By Wet Granulation." Jurnal Kesehatan, Rekam Medis dan Farmasi (JUK-Medifa) 2, no. 01 (2023): 25–31. https://doi.org/10.58471/juk-medifa.v2i01.234.

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n previous studies, the polysaccharide extract of gadung tuber has a hypoglycemic effect, wherein the plant contains a high glycemic index indicating that carbohydrates undergo rapid digestion and are absorbed in large quantities so that blood glucose levels suddenly experience a rapid rise in insulin which can lower cholesterol values. (Sumunar et al., 2015) This research method is an experiment in which this research was carried out, by making starch from gadung starch and making tablets by wet granulation. Based on the results of the research that has been done, it can be concluded that the
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Dissertations / Theses on the topic "Tablet hardness"

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Lin, Su-Chao, and 林素昭. "A Research of Improving The Process of Health Food of Tablet Hardness by DMAIC Model." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/47632143908547165436.

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碩士<br>國立勤益科技大學<br>研發科技與資訊管理研究所<br>102<br>Biotechnology for health-food manufacturing has been developing quickly in recent years, advancing in skill and usages, and health foods been taken widely. According to statistics, in 2011, Taiwan health food market was NT $ 89.6 billion NT dollars, in which capsule formulation accounts for 57%, the first place. Tablet formulation, the second, accounts for 19%. And the market’s demands for health foods will increase in the following few years. Because the tablet appearance diversified , so that is most popular by consumer in all kinds of health food for
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Chang, Kao-Ming, and 張高銘. "Use Design of Experiments Improve Tablets Physical Characteristics Hardness Quality." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/y7hy9r.

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碩士<br>元智大學<br>工業工程與管理學系<br>107<br>Pharmacy’s existence almost as long as like human history. In Chinese mythology from "Shennong test hundreds of plants", which is to well-known mythology in history, to "Compendium of Materia Medica" Systematic collect and categorize great work of pharmacy. The modern scientific knowledge increasingly makes pharmacy improve. One of the scientific foundations of modern pharmacy development is a standard quali-ty. In this paper, use 6 sigma's concept, discuss tablet quality physical about hardness as a target. Use "Response Surface Method" in "Design of Experime
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Book chapters on the topic "Tablet hardness"

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Liebers, Annegret, Dorothea Wagner, and Karsten Weihe. "On the Hardness of Recognizing Bundles in Time Table Graphs." In Graph-Theoretic Concepts in Computer Science. Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/3-540-46784-x_31.

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Lakys, Yahya, Weisheng Zhao, Jacques-Olivier Klein, and Claude Chappert. "Magnetic Look-Up Table (MLUT) Featuring Radiation Hardness, High Performance and Low Power." In Lecture Notes in Computer Science. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-19475-7_29.

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Sowmyasree, Golla Venkata. "Tablets." In A Text Book of Pharmaceutics for I Year Diploma in Pharmacy. THINKPLUS PHARMA PUBLICATIONS, 2024. http://dx.doi.org/10.69613/736rs621.

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Tablets are the most widely used solid dosage form in pharmaceutical practice, offering advantages such as precise dosing, stability, and patient convenience. This section explores the various types of tablets, including immediate-release, modified-release, and orally disintegrating tablets, each designed to meet specific therapeutic needs. The composition of tablets, including active ingredients and excipients such as diluents, binders, disintegrants, and lubricants, is discussed in detail. Tablet manufacturing processes, from wet granulation and dry granulation to direct compression, are exa
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Shailaja, P., N. Sridevi, and CH Dinesh Kumar. "Preparation & Evaluation of Acetylated Jack Fruit Seed Starch as a Carrier for Controlled Release Drug Delivery of Zidovudine Tablets." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00447.

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In the present investigation, an attempt was made to isolate starch from jackfruit seed and acetylation of starch and utilize it as a rate control polymer to design controlled release of the zidovudine. Starch was isolated from jackfruit seeds through alkali extraction processes and evaluated for its physicochemical properties and phytochemical tests. Zidovudine was prepared using the controlled release tablets were prepared by using direct compression method. The jack fruit seed starch has shown good physical, phytochemical properties, and good flow properties. The prepared zidovudine tablet
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Mifsud, Mario, Sue Jickells, Janet Mifsud, and Kim Wolff. "‘Ecstasy’ Tablets: Batch Matching for Forensic Drug Intelligence Purposes in Malta." In Detection of Drug Misuse: Biomarkers, Analytical Advances and Interpretation. The Royal Society of Chemistry, 2017. http://dx.doi.org/10.1039/9781782621577-00288.

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‘Ecstasy’ tablets normally have visual and physical characteristics that are usually produced during the tabletting process. The presence of these features often provides valuable information potentially linking tablets from different drug seizures. The distinguishing features (visual and measurable features) of batches of ‘ecstasy’ tablets seized in Malta were examined in order to determine whether these physical features could link or discriminate between post-tabletting batches for drug intelligence purposes. The hypergeometric sampling method was used to sample ‘ecstasy’ tablets from batch
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"ASTM Standard A255-89 Method for Calculating Hardenability from Composition." In Principles of the Heat Treatment of Plain Carbon and Low Alloy Steels. ASM International, 1996. http://dx.doi.org/10.31399/asm.tb.phtpclas.t64560389.

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Abstract This chapter discusses the method for calculating hardenability from composition. It contains tables listing multiplying factors, carbon content, initial hardness, and 50% martensite hardness. The tables also list Jominy distance for 50% martensite vs. DI (in. and mm), boron factors vs. % carbon and alloy factor, and distance hardness dividing factors for non-boron and boron steels (in. and mm).
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"Alloy Compositions, Standard Designations, and Conversion Factors." In Steel Castings Handbook, 6th ed. ASM International, 1995. http://dx.doi.org/10.31399/asm.tb.sch6.t68200422.

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Moyer, Charles. "Material Hardness Tables, Tests and Data." In Tribology Data Handbook. CRC Press, 1997. http://dx.doi.org/10.1201/9781420050479.bmatt.

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"Postcarburizing Thermal Treatments." In Carburizing. ASM International, 1999. http://dx.doi.org/10.31399/asm.tb.cmp.t66770171.

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Abstract This chapter familiarizes readers with tempering and refrigeration treatments and their effect on case-carburized parts. It explains how tempering makes such parts easier to machine, more structurally and dimensionally stable, and more durable in certain applications. It identifies key process parameters and provides test data showing how they affect hardness, yield strength, bending and contact fatigue, and fracture toughness. It also addresses potential problems stemming from process-related factors such as the presence of hydrogen and the effects of aging and grinding. In regard to
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"Property Comparison Tables: Hardness and Tensile Properties." In Mechanical Testing and Evaluation. ASM International, 2000. http://dx.doi.org/10.31399/asm.hb.v08.a0003331.

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Conference papers on the topic "Tablet hardness"

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Krishnan, Karthik, and Cheng Chau Lum. "Sulfide Stress Cracking Resistance of Quenched and Tempered 41XX Low Alloy Steels with 26 HRC Max Hardness." In CONFERENCE 2024. AMPP, 2024. https://doi.org/10.5006/c2024-20958.

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Abstract Section A.2.2.3.3 and Table A.3 of current NACE MR0175/ISO 15156-2 version (2021/2020)1 allows for use of 41XX type low alloy steels quenched and tempered in the tubular form if the hardness does not exceed 26 HRC for all temperature, all region sour service similar to the sour service guidelines of API 5CT2/ISO 119603 L80 Type 1 and T95 Type 1 grades. While the clause recommends qualification for use in sour service it does not mandate the same. In this work different 41XX grades heat treated in tubular form to 26 HRC max hardness with varying quench and temper treatments were tested
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Wolters, Roy, and Brian Chambers. "Technical Justification of Table A.23 in NACE MR0175/ISO15156-3: the Use of Martensitic Stainless Steels in Wellhead and Valve Components in Sour Oilfield Service." In CORROSION 2012. NACE International, 2012. https://doi.org/10.5006/c2012-01561.

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Abstract This paper describes the results of a laboratory study evaluating environmentally-assisted cracking resistance of cast alloy CA6NM (UNS J91540) in highly sour environments and the implications of the findings on the usage of CA6NM in wellhead components. CA6NM is a commonly used material in wellhead tree components and valve and choke components in oil and gas production. NACE MR0175/ISO15156-3 permits the use of CA6NM, in the proper metallurgical condition, for these applications in any oil and gas production environment provided the pH of that environment is greater than or equal to
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Zhao, Guang, Xianmin Liu, Hui Xie, Yuhang Xu, and Salah Aldeen Abdo Alghurbani. "The design of the tablet hardness tester." In ICMIP 2022: 2022 7th International Conference on Multimedia and Image Processing. ACM, 2022. http://dx.doi.org/10.1145/3517077.3517112.

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May, Robert K., Lianghao Han, Jesse Alton, et al. "Pharmaceutical tablet hardness measurements with thz pulsed imaging." In 2009 34th International Conference on Infrared, Millimeter, and Terahertz Waves (IORMMW-THz 2009). IEEE, 2009. http://dx.doi.org/10.1109/icimw.2009.5325603.

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Kobayashi, Shinji, Takahiro Sato, and Takanori Yamazaki. "Relationship Between Tableting Motion and Tablet Hardness in Compression Molding." In 20th International Conference on Informatics in Control, Automation and Robotics. SCITEPRESS - Science and Technology Publications, 2023. http://dx.doi.org/10.5220/0012230200003543.

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Phutane, Prasanna, Saurabh Sharma, Mukul Khodke, and Prajakta Dandekar. "DOE approach to evaluate the influence of binder concentration and particle size on hardness and disintegration time of herbal tablet." In INTERNATIONAL CONFERENCE ON INTELLIGENT TECHNOLOGIES FOR SUSTAINABLE ENERGY MANAGEMENT AND CONTROL 2023: ITSEMC2023. AIP Publishing, 2024. https://doi.org/10.1063/5.0240387.

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Egboiyi, Benedict O., and Trisha Sain. "Effect of Ion-Exchange Chemistry on the Fracture of Chemically Strengthened Sodium Aluminosilicate Glass." In ASME 2019 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/imece2019-11700.

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Abstract The widespread use of sodium aluminosilicate glass in many critical applications due to its hardness, weight, density and optical properties (transparency, dielectric etc.), instead of metals or plastics has become common in recent years. However, glass which is known to be a brittle material has its own vulnerability to fracture. Processes such as heat treatment (heat tempering) or chemical strengthening, through ion-exchange have been deployed to create residual stress profile on the glass, in a bid to improve its strength for applications such as in the automobile windshield design
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Ibrahim, A., and S. Sampath. "Effect of Grinding Mechanisms on Surface Finish and Hardness of Thermally Sprayed WC-Co." In ITSC 1996, edited by C. C. Berndt. ASM International, 1996. http://dx.doi.org/10.31399/asm.cp.itsc1996p0493.

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Abstract During grinding of thermally sprayed WC-Co, the grinding ratio G ( ratio of volume of work removed to the volume of wheel consumed) is usually low and the finish produced sometimes is inadequate. Improvement in surface finish accompanies increase in grinding ratio. The objective of this investigation is to study the effect of type of abrasive, table speed, and depth of cut on the surface finish and hardness of WC-Co. Thermally sprayed WC-12 wt % Co and WC-17 wt % Co produced using the high velocity oxygen fuel (HVOF) process, have been ground using silicon carbide and diamond wheels u
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Han, Shuai, Nicholas Stiffler, Athanasios Krontiris, Kostas Bekris, and Jingjin Yu. "High-Quality Tabletop Rearrangement with Overhand Grasps: Hardness Results and Fast Methods." In Robotics: Science and Systems 2017. Robotics: Science and Systems Foundation, 2017. http://dx.doi.org/10.15607/rss.2017.xiii.051.

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Wang, Shyh-Jen. "An Experimental Methodology to Evaluate the Rigidity of Penile Prostheses in Vitro." In ASME 2000 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/imece2000-2559.

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Abstract This work investigates the hardness and buckling force of penile prosthesis to further understand the rigidity of penile prosthesis before and after implantation. Evaluated herein are four prosthetic samples (inflatable 3, semi-rigid 1), five realities (inflatable 1, semi-rigid 4), and one after implantation of prosthesis. The hardness is measured with a hardness tester by pressing the tester’s indentor to the surface of the specimen. In addition, a patient after implantation is evaluated with respect to the hardness of penile versus various numbers of pumping. The buckling force of t
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