Academic literature on the topic 'Tachykinins'
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Journal articles on the topic "Tachykinins":
López, B. Díaz, and L. Debeljuk. "Prenatal melatonin and its interaction with tachykinins in the hypothalamic - pituitary - gonadal axis." Reproduction, Fertility and Development 19, no. 3 (2007): 443. http://dx.doi.org/10.1071/rd06140.
Fujii, K., H. Kohrogi, H. Iwagoe, J. Hamamoto, N. Hirata, T. Yamaguchi, O. Kawano, and M. Ando. "Evidence that PGF2 alpha-induced contraction of isolated guinea pig bronchi is mediated in part by release of tachykinins." Journal of Applied Physiology 79, no. 5 (November 1, 1995): 1411–18. http://dx.doi.org/10.1152/jappl.19188.8.131.521.
Payne, Catherine M., Caroline J. Heggie, David G. Brownstein, James P. Stewart, and John P. Quinn. "Role of Tachykinins in the Host Response to Murine Gammaherpesvirus Infection." Journal of Virology 75, no. 21 (November 1, 2001): 10467–71. http://dx.doi.org/10.1128/jvi.75.21.10467-10471.2001.
Weinstock, J. V., and A. M. Blum. "Tachykinin production in granulomas of murine schistosomiasis mansoni." Journal of Immunology 142, no. 9 (May 1, 1989): 3256–61. http://dx.doi.org/10.4049/jimmunol.142.9.3256.
Culman, Juraj, and Thomas Unger. "Central tachykinins: mediators of defence reaction and stress reactions." Canadian Journal of Physiology and Pharmacology 73, no. 7 (July 1, 1995): 885–91. http://dx.doi.org/10.1139/y95-122.
Weil, M., A. Itin, and E. Keshet. "A role for mesenchyme-derived tachykinins in tooth and mammary gland morphogenesis." Development 121, no. 8 (August 1, 1995): 2419–28. http://dx.doi.org/10.1242/dev.121.8.2419.
Maggi, C. A. "Tachykinins, tachykinin receptors and airways pathophysiology." Pharmacological Research 26 (September 1992): 7. http://dx.doi.org/10.1016/1043-6618(92)90726-r.
Goto, Tetsuya, and Teruo Tanaka. "Tachykinins and tachykinin receptors in bone." Microscopy Research and Technique 58, no. 2 (July 15, 2002): 91–97. http://dx.doi.org/10.1002/jemt.10123.
Kagstrom, J., M. Axelsson, J. Jensen, A. P. Farrell, and S. Holmgren. "Vasoactivity and immunoreactivity of fish tachykinins in the vascular system of the spiny dogfish." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 270, no. 3 (March 1, 1996): R585—R593. http://dx.doi.org/10.1152/ajpregu.1996.270.3.r585.
Jensen, J., K. R. Olson, and J. M. Conlon. "Primary structures and effects on gastrointestinal motility of tachykinins from the rainbow trout." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 265, no. 4 (October 1, 1993): R804—R810. http://dx.doi.org/10.1152/ajpregu.1993.265.4.r804.
Dissertations / Theses on the topic "Tachykinins":
Bell, Nicola Jane. "Peripheral tachykinins and tachykinin receptors." Electronic Thesis or Diss., University of Reading, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.428305.
Chambers, J. K. "Molecular forms of tachykinins." Electronic Thesis or Diss., University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334079.
Makeham, John M. "Functional neuroanatomy of tachykinins in brainstem autonomic regulation." Connect to full text, 2006. http://hdl.handle.net/2123/1960.
Title from title screen (viewed 1 November 2007). Submitted in fulfilment of the requirements for the degree of Doctor of Philosophy to the Discipline of Physiology, Faculty of Medicine. Degree awarded 2007 ; thesis submitted 2006. Bibliography: leaves 239-284. Also issued in print.
Patak, Eva Nicole. "Modulation of mammalian uterine contractility by tachykinins." Monash University, Dept. of Pharmacology, 2003. http://arrow.monash.edu.au/hdl/1959.1/9501.
Reynolds, Paul N. "The role of tachykinins in airway inflammation and bronchial hyper-responsiveness /." Title page, contents and abstract only, 1999. http://web4.library.adelaide.edu.au/theses/09PH/09phr464.pdf.
Makeham, John Murray. "Functional neuroanatomy of tachykinins in brainstem autonomic regulation." University of Sydney, 1997. http://hdl.handle.net/2123/1960.
Little is known about the role that tachykinins, such as substance P and its receptor, the neurokinin-1 receptor, play in the generation of sympathetic nerve activity and the integration within the ventrolateral medulla (VLM) of many vital autonomic reflexes such as the baroreflex, chemoreflex, somato-sympathetic reflex, and the regulation of cerebral blood flow. The studies described in this thesis investigate these autonomic functions and the role of tachykinins through physiological (response to hypercapnoea, chapter 3), anatomical (neurokinin-1 receptor immunohistochemistry, chapter 4) and microinjection (neurokinin-1 receptor activation and blockade, chapters 5 and 6) experiments. In the first series of experiments (chapter 3) the effects of chemoreceptor activation with hyperoxic hypercapnoea (5%, 10% or 15% CO2 in O2) on splanchnic sympathetic nerve activity and sympathetic reflexes such as the baroreflex and somato-sympathetic reflex were examined in anaesthetized rats. Hypercapnoea resulted in sympatho-excitation in all groups and a small increase in arterial blood pressure in the 10 % CO2 group. Phrenic nerve amplitude and phrenic frequency were also increased, with the frequency adapting back to baseline during the CO2 exposure. Hypercapnoea selectively attenuated (5% CO2) or abolished (10% and 15% CO2) the somato-sympathetic reflex while leaving the baroreflex unaffected. This selective inhibition of the somato-sympathetic reflex while leaving the baroreflex unaffected was also seen following neurokinin-1 receptor activation in the rostral ventrolateral medulla (RVLM) (see below). Microinjection of substance P analogues into the RVLM results in a pressor response, however the anatomical basis for this response is unknown. In the second series of experiments (chapter 4), the distribution of the neurokinin-1 receptor in the RVLM was investigated in relation to catecholaminergic (putative sympatho-excitatory “C1”) and bulbospinal neurons. The neurokinin-1 receptor was demonstrated on a small percentage (5.3%) of C1 neurons, and a small percentage (4.7%) of RVLM C1 neurons also receive close appositions from neurokinin-1 receptor immunoreactive terminals. This provides a mechanism for the pressor response seen with RVLM microinjection of substance P analogues. Neurokinin-1 receptor immunoreactivity was also seen a region overlapping the preBötzinger complex (the putative respiratory rhythm generation region), however at this level a large percentage of these neurons are bulbospinal, contradicting previous work suggesting that the neurokinin-1 receptor is an exclusive anatomical marker for the propriobulbar rhythm generating neurons of the preBötzinger complex. The third series of experiments (chapter 5) investigated the effects of neurokinin-1 receptor activation and blockade in the RVLM on splanchnic sympathetic nerve activity, arterial blood pressure, and autonomic reflexes such as the baroreflex, somato-sympathetic reflex, and sympathetic chemoreflex. Activation of RVLM neurokinin-1 receptors resulted in sympatho-excitation, a pressor response, and abolition of phrenic nerve activity, all of which were blocked by RVLM pre-treatment with a neurokinin-1 receptor antagonist. As seen with hypercapnoea, RVLM neurokinin-1 receptor activation significantly attenuated the somato-sympathetic reflex but did not affect the sympathetic baroreflex. Further, blockade of RVLM neurokinin-1 receptors significantly attenuated the sympathetic chemoreflex, suggesting a role for RVLM substance P release in this pathway. The fourth series of experiments (chapter 6) investigated the role of neurokinin-1 receptors in the RVLM, caudal ventrolateral medulla (CVLM), and nucleus tractus solitarius (NTS) on regional cerebral blood flow (rCBF) and tail blood flow (TBF). Activation of RVLM neurokinin-1 receptors increased rCBF associated with a decrease in cerebral vascular resistance (CVR). Activation of CVLM neurokinin-1 receptors decreased rCBF, however no change in CVR was seen. In the NTS, activation of neurokinin-1 receptors resulted in a biphasic response in both arterial blood pressure and rCBF, but no significant change in CVR. These findings suggest that in the RVLM substance P and the neurokinin-1 receptor play a role in the regulation of cerebral blood flow, and that changes in rCBF evoked in the CVLM and NTS are most likely secondary to changes in arterial blood pressure. Substance P and neurokinin-1 receptors in the RVLM, CVLM and NTS do not appear to play a role in the brainstem regulation of tail blood flow. In the final chapter (chapter 7), a model is proposed for the role of tachykinins in the brainstem integration of the sympathetic baroreflex, sympathetic chemoreflex, cerebral vascular tone, and the sympatho-excitation seen following hypercapnoea. A further model for the somato-sympathetic reflex is proposed, providing a mechanism for the selective inhibition of this reflex seen with hypercapnoea (chapter 3) and RVLM neurokinin-1 receptor activation (chapter 5). In summary, the ventral medulla is essential for the generation of basal sympathetic tone and the integration of many vital autonomic reflexes such as the baroreflex, chemoreflex, somato-sympathetic reflex, and the regulation of cerebral blood flow. The tachykinin substance P, and its receptor, the neurokinin-1 receptor, have a role to play in many of these vital autonomic functions. This role is predominantly neuromodulatory.
Kaiser, William Joseph. "Peripheral tachykinins in platelets, plasma & endocrine tissues." Electronic Thesis or Diss., University of Reading, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.542266.
Jones, Sarah. "Peripheral tachykinins and the NK1 receptor regulate platelet function." Electronic Thesis or Diss., University of Reading, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493813.
Landis, Geoffrey Carrothers. "Synthesis and biological activities of tachykinin and opioid-related compounds, synthesis of unusual amino acids, and the investigations into the smooth muscle pharmacology of tachykinins." Dissertation-Reproduction (electronic), The University of Arizona, 1989. http://hdl.handle.net/10150/184656.
Schamber, Kristopher Cody. "Tachykinin NK3R protein levels in the PVN of rats following an osmotic challenge." Laramie, Wyo. : University of Wyoming, 2007. http://proquest.umi.com/pqdweb?did=1407489691&sid=1&Fmt=2&clientId=18949&RQT=309&VName=PQD.
Books on the topic "Tachykinins":
Holzer, Peter, ed. Tachykinins. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-642-18891-6.
Eric K. Fernström Symposium (8th 1985 Örenäs Castle, Glumslöv, Sweden). Tachykinin antagonists: Proceedings of the 8th Eric K. Fernström Symposium, held in Örenäs Castle, Glumslöv, Sweden on 10-11 June, 1985. Edited by Håkanson Rolf and Sundler Frank. Amsterdam: Elsevier, 1985.
Buck, Stephen H., ed. The Tachykinin Receptors. Totowa, NJ: Humana Press, 1994. http://dx.doi.org/10.1007/978-1-4612-0301-8.
Rolka, Krzysztof. Chemiczna synteza miniproteinowych inhibitorów enzymów proteolitycznych oraz zmiany strukturalne tachykinin a aktywność biologiczna. Gdańsk: Uniwersytet Gdański, 1991.
Book chapters on the topic "Tachykinins":
Turiault, Marc, Caroline Cohen, Guy Griebel, David E. Nichols, Britta Hahn, Gary Remington, Ronald F. Mucha, et al. "Tachykinins." In Encyclopedia of Psychopharmacology, 1301–3. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-68706-1_210.
Turiault, Marc, Caroline Cohen, and Guy Griebel. "Tachykinins." In Encyclopedia of Psychopharmacology, 1695–98. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-36172-2_210.
Tuluc, Florin. "Tachykinins." In Encyclopedia of Cancer, 1–8. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-27841-9_7200-3.
Holzer, Peter. "Tachykinins." In Drug Development, 113–46. Totowa, NJ: Humana Press, 2000. http://dx.doi.org/10.1007/978-1-59259-202-9_5.
Tuluc, Florin. "Tachykinins." In Encyclopedia of Cancer, 4437–44. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-46875-3_7200.
Turiault, Marc, Caroline Cohen, and Guy Griebel. "Tachykinins." In Encyclopedia of Psychopharmacology, 1–4. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-27772-6_210-2.
Conlon, J. M., C. F. Deacon, M. Thorndyke, L. Thim, and S. Falkmer. "Phylogeny of the Tachykinins." In Substance P and Neurokinins, 15–17. New York, NY: Springer New York, 1987. http://dx.doi.org/10.1007/978-1-4612-4672-5_6.
Manzini, Stefano, Cristina Goso, and Arpad Szallasi. "Sensory Nerves and Tachykinins." In Neuropeptides in Respiratory Medicine, 173–96. Taylor & Francis Group, 6000 Broken Sound Parkway NW, Suite 300, Boca Raton, FL 33487-2742: CRC Press, 2017. http://dx.doi.org/10.4324/9780203745915-9.
Conlon, J. M. "The Tachykinin Peptide Family, with Particular Emphasis on Mammalian Tachykinins and Tachykinin Receptor Agonists." In Handbook of Experimental Pharmacology, 25–61. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-642-18891-6_2.
Helke, Cinda J., and Hiroyuki Ichikawa. "Tachykinins, Tachykinin Receptors, and the Central Control of the Cardiovascular System." In Central Neural Mechanisms in Cardiovascular Regulation, 248–65. Boston, MA: Birkhäuser Boston, 1992. http://dx.doi.org/10.1007/978-1-4684-9184-5_9.
Conference papers on the topic "Tachykinins":
Zaidi, Sarah, George Gallos, and Charles Emala. "Tachykinin Receptors Modulate Human Airway Smooth Muscle Proliferation." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a2146.
Agaeva, G. A. "Computational study of the conformational flexibility of the amphibian tachykinin neuropeptides." In 2012 6th International Conference on Application of Information and Communication Technologies (AICT). IEEE, 2012. http://dx.doi.org/10.1109/icaict.2012.6398530.
Misu, Ryosuke, Taro Noguchi, Hiroaki Ohno, Shinya Oishi, and Nobutaka Fujii. "Structure-Activity Relationship Study of Tachykinin Peptides for the Development of Novel NK3 Receptor Agonists." In The Twenty-Third American and the Sixth International Peptide Symposium. Prompt Scientific Publishing, 2013. http://dx.doi.org/10.17952/23aps.2013.060.
Mohbeddin, Abeer, Nawar Haj Ahmed, and Layla Kamareddine. "The use of Drosophila Melanogaster as a Model Organism to study the effect of Innate Immunity on Metabolism." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0224.
Al-Asmar, Jawaher, Sara Rashwan, and Layla Kamareddine. "The use of Drosophila Melanogaster as a Model Organism to study the effect of Bacterial Infection on Host Survival and Metabolism." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0186.