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1

Echefu, Gift, Daniel Hammett, Amir Ausef, and Lance LaMotte. "Reverse Takutsubo Cardiomyopathy in a Patient with Phlegmasia Cerulea Dolens." Case Reports in Cardiology 2022 (June 22, 2022): 1–6. http://dx.doi.org/10.1155/2022/5413237.

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Reverse takotsubo cardiomyopathy (rTTC) is a rare variant of takotsubo cardiomyopathy (TTC) which is characterized by reversible left ventricular (LV) dysfunction. Emotional and physical stress have been implicated in triggering TTC especially in postmenopausal women. TTC and its variants are becoming more recognized due to the widespread adoption of early coronary angiography in the setting of acute coronary syndromes. A man in his late 50s presented to the emergency department with left lower extremity pain, swelling, and cyanosis. Clinical assessment was consistent with phlegmasia cerulea d
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2

Gaiba, Rahul, Brandon Boyer, and Dexter Jacob. "REVERSE TAKUTSUBO CARDIOMYOPATHY MASCARADING AS AN ACUTE CORONARY SYNDROME." Journal of the American College of Cardiology 77, no. 18 (2021): 2972. http://dx.doi.org/10.1016/s0735-1097(21)04327-8.

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3

Ritchie, David, Terren Trott, Joe Bryant, Seth Stearley, and Brian Adkins. "Takutsubo Cardiomyopathy and Flash Pulmonary Edema In a Trauma Patient." Journal of Emergency Medicine 45, no. 4 (2013): 530–32. http://dx.doi.org/10.1016/j.jemermed.2013.04.027.

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4

Kanuri, S., and P. J. Sirrkay. "Unraveling the mystery of Takutsubo cardiomyopathy: a descendant of COVID-19 heart syndrome." Bulgarian Cardiology 29, no. (2) (2023): 7–12. https://doi.org/10.3897/bgcardio.29.e105075.

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Takutsubo, or stress cardiomyopathy (TCM) is one of the important cardiovascular disorders encountered during the COVID-19 pandemic. We performed a PubMed search of relevant articles and presented this review which included epidemiology, etiopathogenesis, diagnosis and treatment of this clinical disorder. Takutsubo is usually more common in women than men. COVID-19 infection or vaccination can incite severe emotional disorders such as anxiety and depression, which flames up impaired neural networks in the limbic system. This stirs up disorganized regulation of autonomic nervous system with pre
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5

Solangi, Zeeshan, Saad Qadwai, Srikanth Yandrapalli, et al. "Takutsubo Cardiomyopathy: An Exceedingly Rare Occurrence After Orthotopic Heart Transplant (OHT)." Chest 150, no. 4 (2016): 66A. http://dx.doi.org/10.1016/j.chest.2016.08.073.

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6

Kanuri, S., and P. J. Sirrkay. "Unraveling the mystery of Takutsubo cardiomyopathy: a descendant of COVID-19 heart syndrome." Bulgarian Cardiology 29, no. 2 (2023): 7–12. http://dx.doi.org/10.3897/bgcardio.29.e105075.

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Takutsubo, or stress cardiomyopathy (TCM) is one of the important cardiovascular disorders encountered during the COVID-19 pandemic. We performed a PubMed search of relevant articles and presented this review which included epidemiology, etiopathogenesis, diagnosis and treatment of this clinical disorder. Takutsubo is usually more common in women than men. COVID-19 infection or vaccination can incite severe emotional disorders such as anxiety and depression, which flames up impaired neural networks in the limbic system. This stirs up disorganized regulation of autonomic nervous system with pre
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7

Thakkar, Samarthkumar, Harsh P. Patel, Aakash Sheth, et al. "B-PO05-158 ATRIAL FIBRILLATION AND TAKUTSUBO CARDIOMYOPATHY ARE ASSOCIATED WITH INCREASED HEART FAILURE AND ALL-CAUSE MORTALITY." Heart Rhythm 18, no. 8 (2021): S436—S437. http://dx.doi.org/10.1016/j.hrthm.2021.06.1077.

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8

Shehzad, D., A. Mutaal, H. Atique, H. Younis, M. Shehzad, and N. Wassey A. Zara. "Pembrolizumab-induced Takutsubo's, Pneumonitis, and Hypophysitis." Journal of International Case Reports 3, no. 1 (2024): 01–03. https://doi.org/10.5281/zenodo.10597721.

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<strong>Abstract&nbsp;</strong> Immune Checkpoint Inhibitor (ICI) therapy is an evolving landscape. Beyond its initial application in advanced melanoma, it knows occupies a key role in various malignancies, including Non-Small Cell Lung Cancer (NSCLC). While ICIs, such as pembrolizumab, effectively target programmed cell death receptors (programmed death ligand 1) the escalating use of these agents has led to an increased incidence of reported side effects, notably coronary artery spasms, myocarditis, and Takotsubo cardiomyopathy. The presented case involves a 72-year-old woman undergoing sing
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9

Azmath, Misbah, Snigdha Bendaram, Yuichi Igarashi, Hassaan Aftab, and Carl Malchoff. "PSAT006 Two Cases of Pheochromocytoma Associated Takotsubo Syndrome- Importance of Early Recognition and Treatment." Journal of the Endocrine Society 6, Supplement_1 (2022): A88—A89. http://dx.doi.org/10.1210/jendso/bvac150.182.

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Abstract Introduction Pheochromocytoma is a rare catecholamine producing adrenal medullary tumor that classically presents with hypertension. Takutsubo cardiomyopathy (TC) is a rare but increasingly recognized presentation of pheochromocytoma. We present two cases of TC likely caused by pheochromocytoma. Case 1 A 60 y/o male who presented with acute onset nausea, vomiting and abdominal pain. Systolic BP was 150-160 mm Hg, and diastolic BP was 100 mmHg. Troponin was elevated (4.15 ng/ml; nl = 0-0.04). An echocardiogram showed a reduced left ventricular ejection fraction (LVEF) of 15-20% (nl = 5
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10

Zerhoudi, R., I. Essaket, K. Bourzeg, A. Zbitou, and A. Bouzerda. "Apical Ballooning Syndrome: A Cardiac Syndrome Mimicking Acute Myocardial Infarction." Scholars Journal of Medical Case Reports 10, no. 10 (2022): 999–1006. http://dx.doi.org/10.36347/sjmcr.2022.v10i10.003.

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Introduction: Apical ballooning syndrome, Takotsubo cardiomyopathy, or broken heart syndrome, is a rare but currently well recognized clinical entity. It occurs after severe emotional or physical stress, most often in postmenopausal women, and mimics the symptoms and signs of acute coronary syndrome, in the absence of significant coronary injury. This cardiomyopathy is rapidly and completely reversible. The exact pathophysiological mechanism of the condition remains debated; several hypotheses have been put forward, the most credible of which seems to be a sudden hyperadrenergic reaction relat
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11

Abdelgadir, Musa Abdelmajid, Khurram Qayyum, Shahzad Akbar, et al. "Takutsubo cardiomyopathy secondary to phaeochromocytoma a unique presentation." Endocrine Abstracts, February 19, 2025. https://doi.org/10.1530/endoabs.109.p19.

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12

Wardhani, Louisa Fadjri Kusuma, Denny Suwanto, Oryza Sativa, and Achmad Lefi. "C20. Cardiac Arrest in COVID-19 Patient Presenting with Takotsubo Cardiomyopathy." European Heart Journal Supplements 23, Supplement_F (2021). http://dx.doi.org/10.1093/eurheartjsupp/suab125.019.

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Abstract Background Takotsubo cardiomyopathy (TC) presents as a result of catecholamine surge. There are increase of TC among COVID-19 patients, which is induced by cytokine storm. TC is previously known as a self-limiting and benign cardiac manifestation, but it has been uncovered that TC can be associated with fatal cardiac outcome due to cardiogenic shock and life-threatening arrhythmia. Clinical Presentation A 54-year-old woman presented to the emergency department with a fever since 9 days before admission accompanied by DOE, PND, and fatigue that worsened since 5 days before admission. F
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13

Wardhani, Louisa Fadjri Kusuma, Denny Suwanto, Oryza Sativa, and Achmad Lefi. "C20. Cardiac Arrest in COVID-19 Patient Presenting with Takotsubo Cardiomyopathy." European Heart Journal Supplements 23, Supplement_F (2021). http://dx.doi.org/10.1093/eurheartjsupp/suab124.019.

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Abstract Background Takotsubo cardiomyopathy (TC) presents as a result of catecholamine surge. There are increase of TC among COVID-19 patients, which is induced by cytokine storm. TC is previously known as a self-limiting and benign cardiac manifestation, but it has been uncovered that TC can be associated with fatal cardiac outcome due to cardiogenic shock and life-threatening arrhythmia. Clinical Presentation A 54-year-old woman presented to the emergency department with a fever since 9 days before admission accompanied by DOE, PND, and fatigue that worsened since 5 days before admission. F
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14

Pujar, Sanjay, Geetha Ramaswamy, Mandvi Pandey, and Enrique Rincon. "Abstract 18616: When Stress Strikes the Heart: Developing Takotsubo Cardiomyopathy With Uncommon Complications." Circulation 148, Suppl_1 (2023). http://dx.doi.org/10.1161/circ.148.suppl_1.18616.

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Introduction: Takotsubo cardiomyopathy (TCM), also known as stress-induced cardiomyopathy or "broken heart syndrome," is a rare condition that predominantly affects postmenopausal women. The etiology of TCM is not entirely understood, but it is thought to be related to catecholamine-induced myocardial stunning. Clinical presentation typically mimics acute coronary syndrome. Left ventricular outflow tract obstruction (LVOTO) is an uncommon complication of TCM, with only a few cases reported in the literature. Case Presentation: A 78-year-old lady presented with chest pain that started a week ag
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15

Hiltner, Emily P., John Kassotis, and Ankur Sethi. "Abstract 14437: Incidence and Inpatient Outcomes of Takutsubo Cardiomyopathy in the United States- An Analysis of the National Inpatient Sample." Circulation 148, Suppl_1 (2023). http://dx.doi.org/10.1161/circ.148.suppl_1.14437.

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Introduction: Takutsubo cardiomyopathy (TC) has been increasingly recognized as an acute cardiac syndrome characterized by typical wall motion abnormality patterns in the absence of epicardial coronary artery disease. It is unknown whether the incidence and mortality of this entity as characterized by race and gender have changed in recent years. Methods: The National Inpatient database (2009-19) was used to study trends in admissions and outcomes of TC over time. Survey estimation commands were used to determine weighted national estimates. Results: During the study period, the estimated inci
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16

Carlos, Alberto Camarillo Noriega M.D., Aguayo Llamas M.D. Everardo, Luis Gil Hernandez M.D. Jose, Salvador Portero M.D. Rogelio, and Lourdes Pérez Vázquez M.D. Ana. "Takotsubo cardiomyopathy induced by cryoablation. A case report." June 23, 2023. https://doi.org/10.5281/zenodo.8072659.

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<strong>Background</strong> Takotsubo cardiomyopathy is a rare temporary and reversible systolic alteration of the apical area of the left ventricle that resembles an acute myocardial infarction in the absence of coronary artery disease, caused by stress. It is characterized by temporary hypokinesia, dyskinesia, or akinesia in left ventricular segments with or without apical involvement and regional wall motion aberration. We present a case of a 71-year-old woman with medical history of hypertension and paroxysmal atrial fibrillation who underwent cryoablation of pulmonary veins foci; during t
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17

Chandrashekar, N., and B. Arafah. "5142 Pheochromocytoma In The ICU- Hiding In Plain Sight." Journal of the Endocrine Society 8, Supplement_1 (2024). http://dx.doi.org/10.1210/jendso/bvae163.260.

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Abstract Disclosure: N. Chandrashekar: None. B. Arafah: None. Introduction: Pheochromocytomas are catecholamine-secreting tumors that are rare but dangerous and occur in &amp;lt;0.2% of patients with hypertension. Case: A 28 year old female with a 10 year history of hypertension and invasive stage 2b cervical cancer s/p chemoradiation presented to the hospital with circulatory shock from Takutsubo cardiomyopathy requiring intubation, vasopressors, CVVH, and ECMO. The endocrinology service was consulted due to a highly vascular, 3.6 cm, ∼23 Hounsfield units right adrenal mass evidenced on CT ab
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18

Ayyalu, Tanesh K., and Michael Goyfman. "Abstract 12896: Case of Probable Takutsubo's Cardiomyopathy Post Intravenous Immunoglobulin Infusion for Neuromyopathy Syndrome." Circulation 146, Suppl_1 (2022). http://dx.doi.org/10.1161/circ.146.suppl_1.12896.

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Introduction: Takotsubo’s Cardiomyopathy (TCM) is a diagnosis of exclusion recognized by regional left ventricle (LV) dysfunction and absent coronary artery disease. There are isolated reports of patients with autoimmune conditions developing TCM post intravenous immunoglobulin (IVIG). IVIG is a plasma product which inactivates microbial antigens and downregulates certain cytokines, but its cardiac effects are varied. Our case describes a female with progressive neuromyopathy who developed cardiomyopathy post IVIG infusion. Case: A 68 year old female, with type 2 diabetes, hypertension, stroke
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