Relevant bibliographies by topics / Talins and Cancer

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
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Academic literature on the topic 'Talins and Cancer'

Author: Grafiati
Published: 4 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Talins and Cancer"

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Mahmoud, Youns. "Talins and Cancer." Journal of Clinical Microbiology and Biochemical Technology 3, no. 1 (2017): 017–18. https://doi.org/10.17352/jcmbt.000020.

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Talin is a large cytoskeletal adaptor protein that is an important component of focal adhesion complexes of adherent cells. It was originally identified as a component of focal adhesions and ruffling membranes of fibroblasts. It was the first cytoplasmic protein partner of integrins to be identified. Many studies proved that talin connects the intracellular actin cytoskeleton with the extracellular environment through interactions with integral membrane proteins in the dynamic focal adhesions. The modular structure of talin is responsible for its ability to serve as a linker protein. It was th
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Malla, Rama Rao, and Rahul Kumar Vempati. "Talin: A Potential Drug Target for Cancer Therapy." Current Drug Metabolism 21, no. 1 (2020): 25–32. http://dx.doi.org/10.2174/1389200221666200214114018.

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Talin is an intracellular cytoskeletal protein and one of the major components of the focal adhesion complex. It mainly acts as an interlink between transmembrane integrin receptors and cytosolic F-actin. Apart from integrins and actin, it also interacts with various other proteins in the adhesion complex to regulate their functional dynamics. Talin undergoes a variety of post-translational modifications and they are implicated in the control of cell motility. There are two talin isoforms (talin1 and talin2) in mammals and they are encoded by TLN1 and TLN2 genes, respectively. Recent studies s
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Baster, Zbigniew, Lindsay Russell, and Zenon Rajfur. "A Review of Talin- and Integrin-Dependent Molecular Mechanisms in Cancer Invasion and Metastasis." International Journal of Molecular Sciences 26, no. 5 (2025): 1798. https://doi.org/10.3390/ijms26051798.

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Cancer is the second most common cause of death in the world, representing one of the main economic burdens in health care and research. The effort of research has mainly focused on limiting the growth of a localized tumor, but most recently, there has been more attention focused on restricting the spreading of the cancer via invasion and metastasis. The signaling pathways behind these two processes share many molecules with physiological pathways regulating cell adhesion and migration, and, moreover, adhesion and migration processes themselves underlie tumor potential for invasion. In this wo
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Chinthalapudi, Krishna, Erumbi S. Rangarajan, and Tina Izard. "The interaction of talin with the cell membrane is essential for integrin activation and focal adhesion formation." Proceedings of the National Academy of Sciences 115, no. 41 (2018): 10339–44. http://dx.doi.org/10.1073/pnas.1806275115.

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Multicellular organisms have well-defined, tightly regulated mechanisms for cell adhesion. Heterodimeric αβ integrin receptors play central roles in this function and regulate processes for normal cell functions, including signaling, cell migration, and development, binding to the extracellular matrix, and senescence. They are involved in hemostasis and the immune response, participate in leukocyte function, and have biological implications in angiogenesis and cancer. Proper control of integrin activation for cellular communication with the external environment requires several physiological p
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Lu, Ziyao, Shahab Haghollahi, and Muhammad Afzal. "Potential Therapeutic Targets for the Treatment of HPV-Associated Malignancies." Cancers 16, no. 20 (2024): 3474. http://dx.doi.org/10.3390/cancers16203474.

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This review article aims to summarize broadly recent developments in the treatment of HPV-associated cancers, including cervical cancer and head and neck squamous cell carcinoma. Relatively new treatments targeting the key HPV E6 and E7 oncoproteins, including gene editing with TALENs and CRISPR/Cas9, are discussed. Given the increased immunogenicity of HPV-related diseases, other therapies such as PRR agonists, adoptive cell transfer, and tumor vaccines are reaching the clinical trial phase. Due to the mechanism, immunogenicity, and reversibility of HPV carcinogenesis, HPV-related cancers pre
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Yu, Chenghan. "Applications of the CRISPR-Cas9 system in the treatment of KRAS mutated lung cancer." Theoretical and Natural Science 21, no. 1 (2023): 215–19. http://dx.doi.org/10.54254/2753-8818/21/20230868.

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Lung cancer is currently the most prevailed cancer in men, and the second most prevailed cancer in women. It is by far the most fatal cancer with around 21% of overall death from cancer. It is very important to seek a way to treat lung cancers, since too many people died for lung cancers, too many families broke up and collapsed, and too many people are left with broken spirituality and heart. On the other hand, the successful treatment of lung cancer using method of gene editing could symbolize for the success of the appliance of gene editing on other deadly cancers. The main type of gene edi
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Abe, Toshiya, Kenoki Ohuchida, Sho Endo, et al. "Talin1 promotes tumor invasion in pancreatic cancer." Pancreatology 16, no. 4 (2016): S85. http://dx.doi.org/10.1016/j.pan.2016.06.306.

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Hwang, Bor-Jang, Gabrielle Edwards, Cole Davis Knoblich, Khosrow Rezvani, and Valerie Odero-Marah. "Abstract C081: Exploring signaling pathways of tumor-nerve interactions in breast cancer." Cancer Epidemiology, Biomarkers & Prevention 33, no. 9_Supplement (2024): C081. http://dx.doi.org/10.1158/1538-7755.disp24-c081.

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Abstract Abstract Introduction: Among the breast cancer, Triple Negative Breast Cancer (TNBC) is usually aggressive and invasive. In the United States, Black women have the highest TNBC incidence (25.2 per 100,000 women) which is almost double compared to other races (9∼13 per 100,000). Neurite outgrowth also known as autonomic nerve sprouting occurs in tumors and contributes to cancer progression and metastasis. Studies on neurite outgrowth in breast cancer (BCa) are limited, however, one study indicates that TNBC cells (4T1) secrete cytokines that induce neurite outgrowth in neurons, while r
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Paris, Elizabeth, Pincas Bitterman, Sameer Sharma, Sanjib Basu, Janice M. Bahr, and Animesh Barua. "Changes in focal adhesion protein Talin-1 expression during malignant transformation leading to ovarian high-grade serous carcinoma." Journal of Clinical Oncology 40, no. 16_suppl (2022): e17586-e17586. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.e17586.

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e17586 Background: Ovarian high-grade serous carcinoma (HGSC), the most lethal form of ovarian cancer, is often detected at late stages due to the lack of an early detection test resulting in low 5-year survival rates. Information on factors associated with malignant transformation and early metastasis is critical in developing interventional strategies to reduce the incidence and death due to HGSC. Talin-1, a focal adhesion protein, regulates cell–cell adhesion, and induces cytoskeletal remodeling leading to tumor cell migration and adhesion. Destabilization of the cell membrane during malign
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Paris, Elizabeth, Pincas Bitterman, Sameer Sharma, Sanjib Basu, Janice M. Bahr, and Animesh Barua. "Changes in focal adhesion protein Talin-1 expression during malignant transformation leading to ovarian high-grade serous carcinoma." Journal of Clinical Oncology 40, no. 16_suppl (2022): e17586-e17586. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.e17586.

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e17586 Background: Ovarian high-grade serous carcinoma (HGSC), the most lethal form of ovarian cancer, is often detected at late stages due to the lack of an early detection test resulting in low 5-year survival rates. Information on factors associated with malignant transformation and early metastasis is critical in developing interventional strategies to reduce the incidence and death due to HGSC. Talin-1, a focal adhesion protein, regulates cell–cell adhesion, and induces cytoskeletal remodeling leading to tumor cell migration and adhesion. Destabilization of the cell membrane during malign
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Dissertations / Theses on the topic "Talins and Cancer"

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Chivers, Seymour Kimberley-Clair. "Talking to relatives about genetic testing for BRCA1/2 and its risk implications : an on-going discussion." Thesis, University of Southampton, 2013. https://eprints.soton.ac.uk/354118/.

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Background: Access to genetic cancer risk information can be highly dependent on whether familial risks are discussed within the family. Despite its essential role in ensuring family members have access to genetic services, there are a number of gaps in the knowledge available on people’s experiences regarding talking to their relatives about genetic testing for BRCA1/2 and its risk implications. In particular, research to date has focused far more on with whom and why (motivations) family communication regarding genetic testing occurs, rather than when or how it is occurring. Method: The stud
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Branney, Peter, and K. Witty. "Hidden, visceral and traumatic: a dramaturgical approach to men talking about their penis after surgery for penile cancer." Wiley, 2019. http://hdl.handle.net/10454/17499.

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Yes<br>Drawing upon concepts of expressive equipment and body image, the aim of this study is to explore how men diagnosed and treated for penile cancer construct their penis and its surgical disfigurement (penectomy). Using maximum variation sampling with the intention to acquire the broadest range of experiences of stage of disease and treatment, 27 cisgender men (aged 48-83, x=63) who had surgical treatment consented for their data to be archived for analysis. From a dramaturgical perspective, the constructionist thematic analysis explored direct and indirect talk about the penis after su
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Baur, Anna Viola. "Has the tourism development of Cancun really been a success? An analysis from the socio-economic point of view." Thesis, Universidad de las Américas Puebla, 2014. http://catarina.udlap.mx/u_dl_a/tales/documentos/bce/baur_av/.

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Kadwell, Lauren. "Talking about sexuality and intimacy : health professional sexual communication in the context of cancer and palliative care." Thesis, 2016. http://hdl.handle.net/1959.7/uws:36547.

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It is now well established that cancer and cancer treatments often have detrimental impacts on the sexual wellbeing and relationships of palliative patients and their partners. Consequently, most palliative cancer patients have reported wanting the opportunity to discuss the impact of these sexual and intimate changes with health professionals. However, whilst most health professionals working in the field of cancer consider sexual communication and information provision to be important, they have reported that in practice, this rarely happens. Previous research has identified a number of pers
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Books on the topic "Talins and Cancer"

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Matthews, Molly Mahoney. Talent for Living Cassettes presents More than patient: Hope and skills for living with cancer. Edited by Matthews Sharon Mahoney and Talent for Living Cassettes (Firm). Talent for Living Cassettes, 1993.

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Shedd, Charlie W. Remember, I love you: Martha's story. Harper, 1990.

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Rice, Anne. The Tale of the Body Thief: The Vampire Chronicles. Ballantine Books, 1993.

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Rice, Anne. Il ladro di corpi: Romanzo. TEA, 2007.

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Rice, Anne. The Tale of the Body Thief: The Vampire Chronicles. Penguin Books, 1993.

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Rice, Anne. The tale of the body thief. BCA, 1995.

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Rice, Anne. El Ladron de Cuerpos. Atlantida, 1993.

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Rice, Anne. The Tale of the Body Thief: The Vampire Chronicles. Alfred A. Knopf, 1992.

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Rice, Anne. The tale of the body thief. Ballantine Books, 1993.

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Carrier, Roch. The flying canoe. Livres Toundra, 2004.

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Book chapters on the topic "Talins and Cancer"

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Huang, Ronald, and Barak Gaster. "Screening for Lung Cancer." In Chalk Talks in Internal Medicine. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-34814-4_22.

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Klein, Reisa. "Chosen Scars: Breast Cancer and Mastectomy Tattooing as Digital Feminist Body Politics." In Talking Bodies Vol. II. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-36994-1_9.

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Clifton Ling, C. "Rainstorm Over Kyoto: Technology Development and Interdisciplinary Collaboration at Memorial Sloan Kettering Cancer Center." In True Tales of Medical Physics. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-91724-1_9.

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Hård, Mikael. "Communicating and Trading in West Africa: Talking Drums and Pack Animals." In Microhistories of Technology. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-22813-1_3.

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AbstractIn conventional histories of those parts of the world that were colonized, telegraph lines, railroads, and steamships loom large. Scholars of this “tools-of-empire” tradition have often overlooked the technologies of communication and transportation that existed pre-colonization—and played a decisive role also during colonial rule. For example, in West Africa, talking drums, pack animals, and canoes made up the precolonial “technological landscape”—together with techniques for agriculture, hunting, mineral extraction, and manufacturing. Using the case of French-named Côte d’Ivoire, Cha
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Mandal, Shubhjeet, and Piyush Kumar Tiwari. "Gene Therapy and Gene Editing for Cancer Therapeutics." In Research Anthology on Bioinformatics, Genomics, and Computational Biology. IGI Global, 2023. http://dx.doi.org/10.4018/979-8-3693-3026-5.ch033.

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Over the past two decades, developments in human genomics have shown that cancer in the host genome is caused by somatic aberration. This discovery has inspired interest among cancer researchers; many are now using genetic engineering therapeutic methods to improve the cancer regression and seeking a possible cure for the disease. The large gene therapy sector offers a variety of therapies which are likely to become effective in preventing cancer deaths. The latest clinical trials of third generation vaccines for a wide variety of cancers have produced promising results. Cancer virotherapy, wh
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Mandal, Shubhjeet, and Piyush Kumar Tiwari. "Gene Therapy and Gene Editing for Cancer Therapeutics." In Handbook of Research on Advancements in Cancer Therapeutics. IGI Global, 2021. http://dx.doi.org/10.4018/978-1-7998-6530-8.ch004.

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Over the past two decades, developments in human genomics have shown that cancer in the host genome is caused by somatic aberration. This discovery has inspired interest among cancer researchers; many are now using genetic engineering therapeutic methods to improve the cancer regression and seeking a possible cure for the disease. The large gene therapy sector offers a variety of therapies which are likely to become effective in preventing cancer deaths. The latest clinical trials of third generation vaccines for a wide variety of cancers have produced promising results. Cancer virotherapy, wh
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"A Talent for Cancer." In Diary of a Detour. Duke University Press, 2020. http://dx.doi.org/10.1215/9781478012290-056.

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"A Talent for Cancer." In Diary of a Detour. Duke University Press, 2020. http://dx.doi.org/10.2307/j.ctv153k6rm.59.

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Yin, Ling. "Gene Editing in ErbB/HER Family-Mediated Cancer Immunology." In Genome Editing - Recent Advances and Applications [Working Title]. IntechOpen, 2025. https://doi.org/10.5772/intechopen.1008441.

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The ErbB/HER family has an essential role in tumor progression, proliferation, invasion, metastasis, and migration. ErbB/HER-targeted therapeutic agents have emerged as effective therapeutic options to achieve excellent clinical outcomes and boost cancer drug discovery by enhancing treatment efficacy, lowering drug resistance, and minimizing systemic toxicity. Furthermore, combination therapy targeting ErbB/HER family members, as well as hormonal therapy, chemotherapy, immunotherapy, and radiotherapy, also enhances therapeutic effects for cancer immunology. Zinc-finger nucleases (ZFNs), transc
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"56 A Talent for Cancer." In Diary of a Detour. Duke University Press, 2020. http://dx.doi.org/10.1515/9781478012290-057.

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Conference papers on the topic "Talins and Cancer"

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Henley, Candace, Joanne Glenn, Vida Henderson, et al. "Abstract D058: Truth Talking Tour: Women’s sexuality after cancer." In Abstracts: Twelfth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; September 20-23, 2019; San Francisco, CA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7755.disp19-d058.

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Jenkins, V. "Abstract ES9-2: Communicating risk information: talking by numbers." In Abstracts: 2019 San Antonio Breast Cancer Symposium; December 10-14, 2019; San Antonio, Texas. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.sabcs19-es9-2.

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Chandrasekar, Maheshvar, Mukkesh Ganesh, B. Saleena, and Prakash Balasubramanian. "Breast Cancer Histopathological Image Classification using EfficientNet Architecture." In 2020 IEEE International Conference on Technology, Engineering, Management for Societal impact using Marketing, Entrepreneurship and Talent (TEMSMET). IEEE, 2020. http://dx.doi.org/10.1109/temsmet51618.2020.9557441.

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Fallowfield, LJ, and VA Jenkins. "Abstract P4-11-04: Talking about risk in the context of GEomic profiling tests (TARGET)." In Abstracts: 2017 San Antonio Breast Cancer Symposium; December 5-9, 2017; San Antonio, Texas. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.sabcs17-p4-11-04.

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Gilardi, Mara, Simone Bersini, Roger Dale Kamm, Matteo Moretti, and Marco Vanoni. "Abstract A52: Dissection of cancer cells extravasation through human vascularized 3D microfluidic model: The major role of talin-1." In Abstracts: AACR Special Conference on Tumor Metastasis; November 30-December 3, 2015; Austin, TX. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.tummet15-a52.

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Gilardi, Mara, Simone Bersini, Roger Dale Kamm, Matteo Moretti, and Marco Vanoni. "Abstract PR07: Dissection of cancer cells extravasation through human vascularized 3D microfluidic model: The major role of talin-1." In Abstracts: AACR Special Conference on Tumor Metastasis; November 30-December 3, 2015; Austin, TX. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.tummet15-pr07.

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Laudico, Lisa. "Abstract IA09: How Patient Advocates can Advance Cancer Health Equity – Tales from the Frontlines." In Abstracts: AACR Virtual Conference: Thirteenth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; October 2-4, 2020. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7755.disp20-ia09.

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Sahu, Bibhuprasad, Chakradharamahanthi Madhavi, Sasmita Pani, and Jvr Ravindra. "Binary Optimization Using Hybrid Owl Optimization For Biomarker Selection From Cancer Datasets." In 2023 IEEE 3rd International Conference on Technology, Engineering, Management for Societal impact using Marketing, Entrepreneurship and Talent (TEMSMET). IEEE, 2023. http://dx.doi.org/10.1109/temsmet56707.2023.10150104.

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Al-Murad, Abdullah, and Md Foisal Hossain. "Utilizing an Integrated Feature Selection Technique in Ovarian Cancer to Solve Classification Problem." In 2021 IEEE 2nd International Conference on Technology, Engineering, Management for Societal impact using Marketing, Entrepreneurship and Talent (TEMSMET). IEEE, 2021. http://dx.doi.org/10.1109/temsmet53515.2021.9768771.

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Huang, Yen-Hua, Yi-Chun Chen, Shu-Liang Chiang, Thai-Yen Ling, and Te-Sheng Chang. "Abstract 446: Cross-talking of hypoxia stress with IGF-1R signaling in cancer stem cell formation (germline lineage)." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-446.

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Reports on the topic "Talins and Cancer"

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Fearns, Joshua, and Lydia Harriss. Data science skills in the UK workforce. Parliamentary Office of Science and Technology, 2023. http://dx.doi.org/10.58248/pn697.

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This POSTnote looks at specialist data skills in the UK, including for artificial intelligence. It considers demand and supply, workforce demographics, challenges, and initiatives to increase supply. Key points: • Collecting and analysing data offers potential economic and social benefits. Analysis by the McKinsey Global Institute estimated that, by 2030, UK GDP could increase by up to 22% as a result of AI. • Potential societal benefits could range from climate change mitigation, to improving early detection and diagnosis of cancers by using AI to identify patterns from imaging (MRI) scans th
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