Academic literature on the topic 'Tamil Concordances'

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Journal articles on the topic "Tamil Concordances"

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Jacobs, H., J. Iacomini, M. van de Ven, S. Tonegawa, and A. Berns. "Domains of the TCR beta-chain required for early thymocyte development." Journal of Experimental Medicine 184, no. 5 (November 1, 1996): 1833–43. http://dx.doi.org/10.1084/jem.184.5.1833.

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The T cell receptor beta (TCR beta) chain controls the developmental transition from CD4-CD8- to CD4+8+thymocytes. We show that the extracellular constant region and the transmembrane region, but not the variable domain or cytoplasmic tail of the TCR beta chain are required for this differentiation step. TCR beta mutant chains lacking the cytoplasmic tail can be found at the cell surface both in functional TCR/CD3 complexes and in a GPI-anchored monomeric form indicating that the cytoplasmic tail of the TCR beta chain functions as an ER retention signal. The concordance between cell surface expression of the mutant chains as TCR/CD3 complexes and their capacity to mediate thymocyte differentiation supports the CD3 mediated feedback model in which preTCR/CD3 complexes control the developmental transition from CD4-CD8- to CD4+CD8+thymocytes.
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Ramm, Till, Emily J. Roycroft, and Johannes Müller. "Convergent evolution of tail spines in squamate reptiles driven by microhabitat use." Biology Letters 16, no. 2 (February 2020): 20190848. http://dx.doi.org/10.1098/rsbl.2019.0848.

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The repeated evolution of convergent or analogous traits is often used as evidence for adaptive evolution. Squamate reptiles show a high degree of convergence in a variety of morphological traits; however, the evolutionary mechanisms driving these patterns are not fully understood. Here, we investigate the evolution of tail spines, a trait that evolved multiple times in evolutionarily independent clades of lizards. Taking a comparative phylogenetic approach, we use 2877 squamate species to demonstrate that the evolution of spiny tails is correlated with microhabitat use, with species that live in rocky habitats significantly more likely to have evolved spiny tails. In the light of previous behavioural observations, our results suggest that spiny-tailed lizards have an advantage in rocky habitats through predation avoidance, where tail spines are used to prevent extraction from rocky crevices. In concordance with previous research on lizard body armour, our results suggest that the evolution of tail spines is coupled to both a rock-dwelling lifestyle and predator avoidance strategies, and highlight a complex interplay between different selective pressures on the evolution of defensive morphologies in reptiles.
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Cunha, César, Mariela Fernández, Jesús E. García, Verónica Andrea González-López, and Nícolas Romano. "A copula-based consistency analysis of education indicators." 4open 2 (2019): 19. http://dx.doi.org/10.1051/fopen/2019013.

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In this paper we investigate the consistency of quality indicators of the Brazilian public educational system. According to the newspaper Estado de São Paulo – Brazil, of January 18, 2017, only 7.3% of students in the third year of high school have an adequate level of mathematics, this shows the relevance of the evaluation and assessment of the Brazilian educational system. In this paper we explore the dependence between two indicators: (i) mean value between the proportions (in two subjects: Portuguese and Mathematics) of students under the basic level (SARESP classification) and (ii) rate of fails, during the years 2013, 2014 and 2015. (i) and (ii) are bases to define the educational quality of public schools for the population of young people, between 14 and 17 years old. This inspection is carried out through the Bayesian estimation of the parameters of the Asymmetric Cubic Sections (ACS) copula. We show that the dependence profile, year after year, behaves in a very unstable way, although during those years there were no substantial changes which justify such instability. Through the copula we compute conditional probabilities of tail events. We verify that an inversion occurred in the concordance/discordance between (i) and (ii). We compute the probability of (i) assuming high values, conditioned to a threshold in (ii). In 2013, as the threshold in (ii) increases the probability increases (concordance), in 2014 the threshold in (ii) is almost irrelevant to the probability and in 2015, as the threshold in (ii) increases the probability decreases (discordance). The inspection of the tail dependence allows to expose some kind of manipulation, in view of for instance, the maintenance of a global index índice de desenvolvimento da educação de São Paulo (IDESP) used to classify the educational institutions.
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Shan, Wei, Chen Liu, and Jing Yu. "FEATURES OF THE DISCIPLINE KNOWLEDGE NETWORK: EVIDENCE FROM CHINA." Technological and Economic Development of Economy 20, no. 1 (January 28, 2014): 45–64. http://dx.doi.org/10.3846/20294913.2014.825460.

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Interdisciplinary knowledge exchange constitutes a network with discipline nodes and knowledge flow edges. Using data on Chinese academic literature, the current paper establishes a discipline knowledge network and analyses its structural features. Citation analysis is first used to measure the flow of knowledge between disciplines to build a discipline knowledge network. Subsequently, the features of the network, such as degree distribution, degree correlation, knowledge flow mode and other structure properties, are then analysed based on complex networks and social network theory. The tail of the degree distribution of this discipline knowledge network is in concordance with exponential distribution. The network has also a distinct hierarchical structure. Moreover, the knowledge flow between disciplines is directional. It flows from certain basic and academic disciplines to the applied disciplines.
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Ben Othman, Mahmoud, Junkyu Han, Abdelfatteh El Omri, Riadh Ksouri, Mohamed Neffati, and Hiroko Isoda. "Antistress Effects of the Ethanolic Extract fromCymbopogon schoenanthusGrowing Wild in Tunisia." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/737401.

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This study aimed to investigate the antistress properties of the ethanol extract ofCymbopogon schoenanthus(CSEE), growing wild in the southern part of Tunisia. The effect of extracts on H2O2-induced cytotoxicity and stress in human neuroblastoma SH-SY5Y cells. Its effect on stress-induced in ICR mice was exposed to force swim and tail suspension, in concordance with heat shock protein expression (HSP27 and HSP90), corticosterone, and catecholamine neurotransmitters level. Our results demonstrated that pretreatment of SH-SY5Y cells with CSEE at 1/2000, 1/1000, and 1/500 v/v dilutions significantly inversed H2O2-induced neurotoxicity. Moreover, CSEE treatments significantly reversed heat shock protein expression in heat-stressed HSP47-transformed cells (42°C, for 90 min) and mRNA expression of HSP27 and HSP90 in H2O2-treated SH-SY5Y. Daily oral administration of 100 mg/kg and 200 mg/kg CSEE was conducted to ICR mice for 2 weeks. It was resulted in a significant decrease of immobility time in forced swimming and tail suspension tests. The effect of CSEE on animal behavior was concordant with a significant regulation of blood serum corticosterone and cerebral cortex levels of catecholamine (dopamine, adrenaline, and noradrenaline). Therefore, this study was attempted to demonstrate the preventive potential of CSEE against stress disorders atin vitroandin vivolevels.
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Aldhufairi, Fadal Abdullah-A., Ranadeera G. M. Samanthi, and Jungsywan H. Sepanski. "New Families of Bivariate Copulas via Unit Lomax Distortion." Risks 8, no. 4 (October 14, 2020): 106. http://dx.doi.org/10.3390/risks8040106.

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This article studies a new family of bivariate copulas constructed using the unit-Lomax distortion derived from a transformation of the non-negative Lomax random variable into a variable whose support is the unit interval. Existing copulas play the role of the base copulas that are distorted into new families of copulas with additional parameters, allowing more flexibility and better fit to data. We present general forms for the new bivariate copula function and its conditional and density distributions. The properties of the new family of the unit-Lomax induced copulas, including the tail behaviors, limiting cases in parameters, Kendall’s tau, and concordance order, are investigated for cases when the base copulas are Archimedean, such as the Clayton, Gumbel, and Frank copulas. An empirical application of the proposed copula model is presented. The unit-Lomax distorted copula models outperform the base copulas.
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7

Ramachandran, A. V., R. V. Kinariwala, and R. V. Shah. "Haematopoiesis and Regeneration: Changes in the Liver, Spleen, Bone Marrow and Hepatic Iron Content during Tail Regeneration in the Scincid Lizard, Mabuya Carinata (Boulenger)." Amphibia-Reptilia 6, no. 4 (1985): 377–86. http://dx.doi.org/10.1163/156853885x00362.

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AbstractIn response to the observed changes in blood during tail regeneration, a detailed histophysiological study of the haemopoietic organs such as liver, spleen and bone marrow was undertaken. During regeneration, all three organs were found to undergo histophysiological changes. Increased haemopoietic activity in the marrow and hyperplasia of the white pulp were the important changes shown by the bone marrow and spleen respectively. In the liver, the most marked effect appeared to be the formation of large numbers of lymphocytopoietic nodules. Another interesting observation was the influx and destruction of red blood cells both in the liver and spleen, once during the early regressive phase and once during the late progressive phase of regeneration. An attempt is made to correlate these changes in the three haemopoietic organs with the possible involvement of lymphocytes in the formation of a regeneration blastema and a possible haemoglobin transition during regeneration. The present observations are in concordance with the previous observations on blood.
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8

Cole, David E. C., Francisco H. J. Yun, Betty Y. L. Wong, Andrew Y. Shuen, Ronald A. Booth, Alfredo Scillitani, Svetlana Pidasheva, Xiang Zhou, Lucie Canaff, and Geoffrey N. Hendy. "Calcium-sensing receptor mutations and denaturing high performance liquid chromatography." Journal of Molecular Endocrinology 42, no. 4 (January 29, 2009): 331–39. http://dx.doi.org/10.1677/jme-08-0164.

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The calcium-sensing receptor (CASR), a plasma membrane G-protein-coupled receptor, is expressed in parathyroid gland and kidney, and controls systemic calcium homeostasis. Inactivating CASR mutations are associated with familial hypocalciuric hypercalcemia (FHH) and neonatal severe hyperparathyroidism, and activating mutations cause autosomal dominant hypocalcemia (ADH). CASR mutation identification plays an important role in the clinical management of mineral metabolism disorders. We describe here a high-throughput method using screening with denaturing high performance liquid chromatography (DHPLC) to initially interrogate 12 amplicons covering translated exons and exon/intron boundaries, followed by sequencing of any amplicon with a modified melting curve relative to wild type, and direct sequencing of a 13th amplicon encoding the COOH-terminal tail to distinguish causative mutations from three common missense single nucleotide polymorphisms. A blinded analysis of 32 positive controls representing mutations throughout the CASR sequence, as well as 22 negative controls, yielded a concordance rate of 100%. We report eight novel and five recurrent FHH mutations, along with six novel and two recurrent ADH mutations. Thus, DHPLC provides a rapid and effective means to screen for CASR mutations.
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9

Prabha, K. Radha Raja, and A. Sathish Selvakumar. "A clinico-epidemiological study of HIV seroconcordant and serodiscordant couples." International Journal of Research in Dermatology 5, no. 1 (January 25, 2019): 72. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20185129.

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<p class="abstract"><strong>Background:</strong> The aim of the present study was to assess the epidemiological and risk factors that are likely to influence HIV transmission among married couples and to study the pattern of sexually transmitted infections among both concordant and discordant HIV infected couples..</p><p class="abstract"><strong>Methods:</strong> This cross-sectional study was done on 100 HIV patients and their married partners attending to Institute of Venereology, Madras Medical College, Tamil Nadu. Detailed history of their high risk sexual behaviour, previous veneral diseases (PVDs) was noted and physical and genital examination was done. All the partners of HIV cases were examined for HIV to know the serostatus (seroconcordant and serodiscordant).<strong></strong></p><p class="abstract"><strong>Results:</strong> Among the 100 married couples, 65 couples were seroconcordant for HIV and 35 couples were serodiscordant. Of them, 94 males and 71 females were positive for HIV. History of PVDs was found in 34 patients (28 were seroconcordants and 6 were serodiscordants). The most common STD in the males noticed was ano-genital warts (n=11) and genital ulceration (n=11) is associated with maximum seroconcordance rates. Whereas in the females it was bacterial vaginosis (n=11).</p><p class="abstract"><strong>Conclusions:</strong> The findings suggest that risk factors such as STDs, PVDs in males, anal intercourse, sexual contact during menstruation, avoidance of condom during sexual act and lack of circumcision was significantly associated with presence of HIV concordance in the study population. Duration and frequency of sexual contact with partner, previous venereal diseases in females and ART were found not to influence the transmission of HIV.</p>
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10

Cherny, Nathan I., Elisabeth G. E. de Vries, Urania Dafni, Elizabeth Garrett-Mayer, Shannon E. McKernin, Martine Piccart, Nicola J. Latino, et al. "Comparative Assessment of Clinical Benefit Using the ESMO-Magnitude of Clinical Benefit Scale Version 1.1 and the ASCO Value Framework Net Health Benefit Score." Journal of Clinical Oncology 37, no. 4 (February 1, 2019): 336–49. http://dx.doi.org/10.1200/jco.18.00729.

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PURPOSE To better understand the European Society for Medical Oncology-Magnitude of Clinical Benefit Scale version 1.1 (ESMO-MCBS v1.1) and the ASCO Value Framework Net Health Benefit score version 2 (ASCO-NHB v2), ESMO and ASCO collaborated to evaluate the concordance between the frameworks when used to assess clinical benefit attributable to new therapies. METHODS The 102 randomized controlled trials in the noncurative setting already evaluated in the field testing of ESMO-MCBS v1.1 were scored using ASCO-NHB v2 by its developers. Measures of agreement between the frameworks were calculated and receiver operating characteristic curves used to define thresholds for the ASCO-NHB v2 corresponding to ESMO-MCBS v1.1 categories. Studies with discordant scoring were identified and evaluated to understand the reasons for discordance. RESULTS The correlation of the 102 pairs of scores for studies in the noncurative setting is estimated to be 0.68 (Spearman’s rank correlation coefficient; overall survival, 0.71; progression-free survival, 0.67). Receiver operating characteristic curves identified thresholds for ASCO-NHB v2 for facilitating comparisons with ESMO-MCBS v1.1 categories. After applying pragmatic threshold scores of 40 or less (ASCO-NHB v2) and 2 or less (ESMO-MCBS v1.1) for low benefit and 45 or greater (ASCO-NHB v2) and 4 to 5 (ESMO-MCBS v1.1) for substantial benefit, 37 discordant studies were identified. Major factors that contributed to discordance were different approaches to evaluation of relative and absolute gain for overall survival and progression-free survival, crediting tail of the curve gains, and assessing toxicity. CONCLUSION The agreement between the frameworks was higher than observed in other studies that sought to compare them. The factors that contributed to discordant scores suggest potential approaches to improve convergence between the scales.
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Dissertations / Theses on the topic "Tamil Concordances"

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González, Coronado Sanjuanita Ivette, Coronado Sanjuanita Ivette González, and Sánchez Rogelio Gutiérrez. "Lesiones de Mama BIRADS 4 y 5 mastográfico y su concordancia histopatológica en pacientes de Tamiz del Hospital Materno Perinatal Mónica Pretelini, durante el periodo del 1° de junio del 2011 al 31 de mayo del 2012." Tesis de Licenciatura, Medicina-Quimica, 2013. http://ri.uaemex.mx/handle/20.500.11799/13834.

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INTRODUCCION. El cáncer de mama es el tipo más frecuente de cáncer en las mujeres en México. La mastografía de escrutinio es el estándar de oro en la detección temprana del cáncer de mama; como método de tamiz tiene una sensibilidad (86%) y especificidad (96%). La “NORMA Oficial Mexicana NOM-041-SSA2-2011 indica que debe realizarse cada 2 años. El Colegio Americano de Radiología (ACR) recomienda una mastografía anual a partir de los 40 años de edad. La mastografía y el ultrasonido juegan un papel vital en la detección oportuna del cáncer de mama, al detectar lesiones no palpables, y lograr la clasificación de las lesiones mamarias con respeto al riesgo de presentar cáncer de acuerdo con los hallazgos morfológicos y radiológicos, mediante el Sistema de Reporte de Datos de las Imágenes de la Mama (BIRADS) nos orienta respecto a la conducta a seguir ya sea al control anual, la vigilancia a corto plazo, o la biopsia mamaria. OBJETIVO: Determinar el nivel de concordancia de lesiones de mama categorizadas BIRADS 4 y 5 mastográfico con histopatología en pacientes de tamiz del Hospital Materno perinatal “Mónica Pretelini” durante el periodo del 1º de Junio del 2011 al 31 de mayo del 2012. MATERIAL Y METODOS El presente estudio contempla los expedientes radiológicos e histopatológicos de las pacientes que acuden a realización de mastografía de tamiz, y se les detecta por medio de a mastografía lesión clasificada como BIRADS 4 Y 5 y que posteriormente se realizó biopsia. RESULTADOS. Del total de mastografías realizadas (3115) durante el periodo de estudio, 106 se reportaron como BIRADS 4 (75 %) y 35 como BIRADS 5 (25%) por imagen. Se corroboraron por histopatología 43 casos de cáncer de mama, correspondiendo al 30% del total de las biopsias realizadas, de las cuales 18 correspondían a BIRADS 4 y 25 a BIRADS 5; con un porcentaje de concordancia del total de las biopsias de 16% para BIRADS 4 y 71 % para BIRADS 5.
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Books on the topic "Tamil Concordances"

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Pārati, Tiruvēṅkaṭa. Pāratitīpam: Akarātiyum mūlamum. Cen̲n̲ai: Cen̲n̲aip Palkalaikkal̲akam, 2007.

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Pārati, Tiruvēṅkaṭa. Pāratitīpam: Akarātiyum mūlamum. Cen̲n̲ai: Cen̲n̲aip Palkalaikkal̲akam, 2007.

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Jē, Āppilpi Ec. Vētākama col akarāti. Cen̲n̲ai: Cuvicēṣa Ūl̲iya Nūl Nilaiyam, 1989.

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Cīnivācan̲, Ku. Caṅka ilakkiyat tāvaraṅkaḷ. Tañcāvūr: Tamil̲p Palkalaik Kal̲akam, 1987.

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Thomas, Lehmann. A word index for Caṅkam literature. Madras: Institute of Asian Studies, 1993.

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1820-1908, Pope G. U., ed. Nālaṭiyār =: The Naladiyar, or, Four hundred quatrains in Tamil : with introduction, translation, and notes critical, philological, and explanatory to which is added a concordance and lexicon. New Delhi: Asian Educational Services, 1997.

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