Log in

Relevant bibliographies by topics / Tanyctes / Journal articles

To see the other types of publications on this topic, follow the link: Tanyctes.

Journal articles on the topic 'Tanyctes'

Author: Grafiati

Published: 16 November 2024

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Tanyctes.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Yoo, Sooyeon, Juhyun Kim, Pin Lyu, et al. "Control of neurogenic competence in mammalian hypothalamic tanycytes." Science Advances 7, no. 22 (2021): eabg3777. http://dx.doi.org/10.1126/sciadv.abg3777.

Full text

Abstract:

Hypothalamic tanycytes, radial glial cells that share many features with neuronal progenitors, can generate small numbers of neurons in the postnatal hypothalamus, but the identity of these neurons and the molecular mechanisms that control tanycyte-derived neurogenesis are unknown. In this study, we show that tanycyte-specific disruption of the NFI family of transcription factors (Nfia/b/x) robustly stimulates tanycyte proliferation and tanycyte-derived neurogenesis. Single-cell RNA sequencing (scRNA-seq) and single-cell assay for transposase-accessible chromatin sequencing (scATAC-seq) analys

APA, Harvard, Vancouver, ISO, and other styles

2

Wittmann, Gabor, Surbhi Gahlot, Malcolm James Low, and Ronald M. Lechan. "Rax Expression Identifies a Novel Cell Type in the Adult Mouse Hypothalamus." Journal of the Endocrine Society 5, Supplement_1 (2021): A42. http://dx.doi.org/10.1210/jendso/bvab048.082.

Full text

Abstract:

Abstract Hypothalamic tanycytes are radial glia-like ependymal cells lining the ventrolateral walls and floor of the third ventricle. Recent data show that tanycytes are adult neural stem/progenitor cells, capable of generating neurons that populate the adjacent hypothalamic nuclei involved in the regulation of feeding and energy balance. Thus, the genetic fate mapping of tanycytes has become an invaluable tool to identify and study tanycyte-derived adult-born hypothalamic neurons. Perhaps the most selective tanycyte marker identified to date is the retina and anterior neural fold homeobox (Ra

APA, Harvard, Vancouver, ISO, and other styles

3

Bolborea, Matei, Marie-Pierre Laran-Chich, Kamontip Rasri, et al. "Melatonin Controls Photoperiodic Changes in Tanycyte Vimentin and Neural Cell Adhesion Molecule Expression in the Djungarian Hamster (Phodopus sungorus)." Endocrinology 152, no. 10 (2011): 3871–83. http://dx.doi.org/10.1210/en.2011-1039.

Full text

Abstract:

The Djungarian hamster displays photoperiodic variations in gonadal size synchronized to the seasons by the nightly secretion of the pineal hormone melatonin. In short photoperiod (SP), the gonads regress in size, and circulating sex steroids levels decline. Thus, the brain is subject to seasonal variations of both melatonin and sex steroids. Tanycytes are specialized glial cells located in the ependymal lining of the third ventricle. They send processes either to the meninges or to blood vessels of the medio-basal hypothalamus. Furthermore, they are known to locally modulate GnRH release in t

APA, Harvard, Vancouver, ISO, and other styles

4

de Vries, E. M., J. Kwakkel, L. Eggels та ін. "NFκB Signaling Is Essential for the Lipopolysaccharide-Induced Increase of Type 2 Deiodinase in Tanycytes". Endocrinology 155, № 5 (2014): 2000–2008. http://dx.doi.org/10.1210/en.2013-2018.

Full text

Abstract:

The enzyme type 2 deiodinase (D2) is a major determinant of T3 production in the central nervous system. It is highly expressed in tanycytes, a specialized cell type lining the wall of the third ventricle. During acute inflammation, the expression of D2 in tanycytes is up-regulated by a mechanism that is poorly understood at present, but we hypothesized that cJun N-terminal kinase 1 (JNK1) and v-rel avian reticuloendotheliosis viral oncogene homolog A (RelA) (the 65 kD subunit of NFκB) inflammatory signal transduction pathways are involved. In a mouse model for acute inflammation, we studied t

APA, Harvard, Vancouver, ISO, and other styles

5

Jawad, Haider, Muthanna Al-Kaabi, and Anam Al-Salihi. "IMMUNOHISTOCHEMICAL EXPRESSION OF MONOCARBOXYLATE TRANSPORTER 1&4 IN TANYCYTE–LIKE CELLS OF THE SULCUS MEDIANUS ORGANUM." Iraqi Journal of Medical Sciences 17, no. 1 (2019): 83–99. http://dx.doi.org/10.22578/ijms.17.1.12.

Full text

Abstract:

Background: Circumventricular organs (CVOs) are specialized structures border the brain ventricles and lack the blood-brain barrier. These CVOs are lined by specialized ependymal cells (ECs) called tanycyte. The sulcus medianus organum (SMO) locates at the floor of the 4th ventricle at the rostral part of the sulcus medianus (SM). Objective: To explore the expression of the monocarboxylate transporter 1 and monocarboxylate transporter 4 (MCT1 & MCT4) in the tanycytes of the median eminence (ME) and tanycyte-like cells of the SMO to add a functional evidence for describing the SMO as anothe

APA, Harvard, Vancouver, ISO, and other styles

6

de Seranno, Sandrine, Xavier d'Anglemont de Tassigny, Cecilia Estrella, et al. "Role of Estradiol in the Dynamic Control of Tanycyte Plasticity Mediated by Vascular Endothelial Cells in the Median Eminence." Endocrinology 151, no. 4 (2010): 1760–72. http://dx.doi.org/10.1210/en.2009-0870.

Full text

Abstract:

In the ever-changing physiological context of the neuroendocrine brain, the mechanisms by which cellular events involving neurons, astroglia, and vascular cells are coordinated to bring forth the appropriate neuronal signaling is not yet known but is amenable to examination. In the median eminence of the hypothalamus, endothelial cells are key players in the plasticity of tanycytes (specialized astroglia) and neuroendocrine synapse efficacy. Here we report that estradiol acts on both purified endothelial cells and isolated tanycytes to trigger endothelial-to-glial communication that leads to a

APA, Harvard, Vancouver, ISO, and other styles

7

Bolborea, Matei, Gisela Helfer, Francis J. P. Ebling, and Perry Barrett. "Dual signal transduction pathways activated by TSH receptors in rat primary tanycyte cultures." Journal of Molecular Endocrinology 54, no. 3 (2015): 241–50. http://dx.doi.org/10.1530/jme-14-0298.

Full text

Abstract:

Tanycytes play multiple roles in hypothalamic functions, including sensing peripheral nutrients and metabolic hormones, regulating neurosecretion and mediating seasonal cycles of reproduction and metabolic physiology. This last function reflects the expression of TSH receptors in tanycytes, which detect photoperiod-regulated changes in TSH secretion from the neighbouringpars tuberalis. The present overall aim was to determine the signal transduction pathway by which TSH signals in tanycytes. Expression of the TSH receptor in tanycytes of 10-day-old Sprague Dawley rats was observed byin situhyb

APA, Harvard, Vancouver, ISO, and other styles

8

Sánchez, Edith, Praful S. Singru, Gábor Wittmann та ін. "Contribution of TNF-α and Nuclear Factor-κB Signaling to Type 2 Iodothyronine Deiodinase Activation in the Mediobasal Hypothalamus after Lipopolysaccharide Administration". Endocrinology 151, № 8 (2010): 3827–35. http://dx.doi.org/10.1210/en.2010-0279.

Full text

Abstract:

To determine whether signaling through TNF and/or nuclear factor-κB contributes to bacterial lipopolysaccharide (LPS)-induced activation of type 2 iodothyronine deiodinase (D2) in tanycytes lining the floor and infralateral walls of the third ventricle, the effect of a TNF antagonist on D2 gene expression and LPS-induced Iκ-Bα expression in tanycytes were studied. Animals treated with soluble, rat, polyethylene glycol-conjugated TNF receptor type 1 (4 mg/kg body weight) before a single ip injection of LPS showed a significant reduction in circulating IL-6 levels but no effect on LPS-induced D2

APA, Harvard, Vancouver, ISO, and other styles

9

Porniece Kumar, Marta, Anna Lena Cremer, Paul Klemm, et al. "Insulin signalling in tanycytes gates hypothalamic insulin uptake and regulation of AgRP neuron activity." Nature Metabolism 3, no. 12 (2021): 1662–79. http://dx.doi.org/10.1038/s42255-021-00499-0.

Full text

Abstract:

AbstractInsulin acts on neurons and glial cells to regulate systemic glucose metabolism and feeding. However, the mechanisms of insulin access in discrete brain regions are incompletely defined. Here we show that insulin receptors in tanycytes, but not in brain endothelial cells, are required to regulate insulin access to the hypothalamic arcuate nucleus. Mice lacking insulin receptors in tanycytes (IR∆Tan mice) exhibit systemic insulin resistance, while displaying normal food intake and energy expenditure. Tanycytic insulin receptors are also necessary for the orexigenic effects of ghrelin, b

APA, Harvard, Vancouver, ISO, and other styles

10

Rafiei, Parisa, Huda S. Mian, Shruthi H. Iyer, et al. "In Preclinical Epilepsy, GLUT1 and GFAP Dysregulation in Cells Surrounding the Third Ventricle, Including Tanycytes, Is Differentially Restored with Ketogenic Diet Treatment." Nutrients 17, no. 11 (2025): 1824. https://doi.org/10.3390/nu17111824.

Full text

Abstract:

Background/Objectives: Hyperexcitable neuronal activity associated with seizures may disrupt brain homeostasis resulting in abnormal glucose and nutrient management and metabolism. Specialized ependymal cells known as tanycytes line the third ventricle wall bridging communication between the brain, CSF, and blood. Despite their positional importance, whether tanycytes are impacted by epilepsy is unknown. Here, known protein markers of tanycytes were assessed in the Kcna1-null mouse model of genetic epilepsy with spontaneous recurrent seizures (SRS mice). Further, whether an anti-seizure metabo

APA, Harvard, Vancouver, ISO, and other styles

11

Barrett, Perry, Elena Ivanova, E. Scott Graham, et al. "Photoperiodic regulation of cellular retinoic acid-binding protein 1, GPR50 and nestin in tanycytes of the third ventricle ependymal layer of the Siberian hamster." Journal of Endocrinology 191, no. 3 (2006): 687–98. http://dx.doi.org/10.1677/joe.1.06929.

Full text

Abstract:

Tanycytes in the ependymal layer of the third ventricle act both as a barrier and a communication gateway between the cerebrospinal fluid, brain and portal blood supply to the pituitary gland. However, the range, importance and mechanisms involved in the function of tanycytes remain to be explored. In this study, we have utilized a photoperiodic animal to examine the expression of three unrelated gene sequences in relation to photoperiod-induced changes in seasonal physiology and behaviour. We demonstrate that cellular retinoic acid-binding protein 1 (CRBP1), a retinoic acid transport protein,

APA, Harvard, Vancouver, ISO, and other styles

12

Schlagal, Caitlin R., and Ping Wu. "Alcohol and Cocaine Combined Substance Use on Adult Hypothalamic Neural Stem Cells and Neurogenesis." Brain Plasticity 6, no. 1 (2020): 41–46. http://dx.doi.org/10.3233/bpl-190091.

Full text

Abstract:

Many advancements have been made over the years looking at the individual and combined effects of drugs of abuse on the brain, with one key area of research focusing on the effects on neurogenesis. An integral part of fetal brain development and, later, maintenance in the adult brain, neurogenesis occurs in three main regions: subventricularzone of the lateral ventricles (SVZ), subgranularzone of the dentate gyrus (SGZ), and the tanycyte layer in the hypothalamus (TL). We will review current literature on combined drugs of abuse and their effect on adult neurogenesis. More specifically, this r

APA, Harvard, Vancouver, ISO, and other styles

13

Marsili, Alessandro, Edith Sanchez, Praful Singru, et al. "Thyroxine-induced expression of pyroglutamyl peptidase II and inhibition of TSH release precedes suppression of TRH mRNA and requires type 2 deiodinase." Journal of Endocrinology 211, no. 1 (2011): 73–78. http://dx.doi.org/10.1530/joe-11-0248.

Full text

Abstract:

Suppression of TSH release from the hypothyroid thyrotrophs is one of the most rapid effects of 3,3′,5′-triiodothyronine (T3) or thyroxine (T4). It is initiated within an hour, precedes the decrease in TSHβ mRNA inhibition and is blocked by inhibitors of mRNA or protein synthesis. TSH elevation in primary hypothyroidism requires both the loss of feedback inhibition by thyroid hormone in the thyrotrophs and the positive effects of TRH. Another event in this feedback regulation may be the thyroid hormone-mediated induction of the TRH-inactivating pyroglutamyl peptidase II (PPII) in the hypothala

APA, Harvard, Vancouver, ISO, and other styles

14

Ceriani, Ricardo, and Kathleen E. Whitlock. "Gonadotropin Releasing Hormone (GnRH) Triggers Neurogenesis in the Hypothalamus of Adult Zebrafish." International Journal of Molecular Sciences 22, no. 11 (2021): 5926. http://dx.doi.org/10.3390/ijms22115926.

Full text

Abstract:

Recently, it has been shown in adult mammals that the hypothalamus can generate new cells in response to metabolic changes, and tanycytes, putative descendants of radial glia, can give rise to neurons. Previously we have shown in vitro that neurospheres generated from the hypothalamus of adult zebrafish show increased neurogenesis in response to exogenously applied hormones. To determine whether adult zebrafish have a hormone-responsive tanycyte-like population in the hypothalamus, we characterized proliferative domains within this region. Here we show that the parvocellular nucleus of the pre

APA, Harvard, Vancouver, ISO, and other styles

15

Murphy, Michelle, and Francis J. P. Ebling. "The Role of Hypothalamic Tri-Iodothyronine Availability in Seasonal Regulation of Energy Balance and Body Weight." Journal of Thyroid Research 2011 (2011): 1–7. http://dx.doi.org/10.4061/2011/387562.

Full text

Abstract:

Seasonal cycles of body weight provide a natural model system to understand the central control of energy balance. Studies of such cycles in Siberian hamsters suggest that a change in the hypothalamic availability of thyroid hormone is the key determinant of annual weight regulation. Uptake of thyroid hormone into the hypothalamus from the peripheral circulation occurs largely through a specific monocarboxylate transporter expressed by tanycyte cells lining the third ventricle. Tanycytes are the principal brain cell type expressing type II and type III deiodinases, so they control the local co

APA, Harvard, Vancouver, ISO, and other styles

16

Lewis, Jo E., John M. Brameld, Phil Hill, et al. "Thyroid hormone and vitamin D regulate VGF expression and promoter activity." Journal of Molecular Endocrinology 56, no. 2 (2015): 123–34. http://dx.doi.org/10.1530/jme-15-0224.

Full text

Abstract:

The Siberian hamster (Phodopus sungorus) survives winter by decreasing food intake and catabolizing abdominal fat reserves, resulting in a sustained, profound loss of body weight. Hypothalamic tanycytes are pivotal for this process. In these cells, short-winter photoperiods upregulate deiodinase 3, an enzyme that regulates thyroid hormone availability, and downregulate genes encoding components of retinoic acid (RA) uptake and signaling. The aim of the current studies was to identify mechanisms by which seasonal changes in thyroid hormone and RA signaling from tanycytes might ultimately regula

APA, Harvard, Vancouver, ISO, and other styles

17

Sánchez, Edith, Miguel Angel Vargas, Praful S. Singru, et al. "Tanycyte Pyroglutamyl Peptidase II Contributes to Regulation of the Hypothalamic-Pituitary-Thyroid Axis through Glial-Axonal Associations in the Median Eminence." Endocrinology 150, no. 5 (2009): 2283–91. http://dx.doi.org/10.1210/en.2008-1643.

Full text

Abstract:

Pyroglutamyl peptidase II (PPII), a highly specific membrane-bound metallopeptidase that inactivates TRH in the extracellular space, is tightly regulated by thyroid hormone in cells of the anterior pituitary. Whether PPII has any role in the region where axons containing hypophysiotropic TRH terminate, the median eminence, is unknown. For this purpose, we analyzed the cellular localization and regulation of PPII mRNA in the mediobasal hypothalamus in adult, male rats. PPII mRNA was localized in cells lining the floor and infralateral walls of the third ventricle and coexpressed with vimentin,

APA, Harvard, Vancouver, ISO, and other styles

18

Bolborea, Matei, Eric Pollatzek, Heather Benford, Tamara Sotelo-Hitschfeld, and Nicholas Dale. "Hypothalamic tanycytes generate acute hyperphagia through activation of the arcuate neuronal network." Proceedings of the National Academy of Sciences 117, no. 25 (2020): 14473–81. http://dx.doi.org/10.1073/pnas.1919887117.

Full text

Abstract:

Hypothalamic tanycytes are chemosensitive glial cells that contact the cerebrospinal fluid in the third ventricle and send processes into the hypothalamic parenchyma. To test whether they can activate neurons of the arcuate nucleus, we targeted expression of a Ca2+-permeable channelrhodopsin (CatCh) specifically to tanycytes. Activation of tanycytes ex vivo depolarized orexigenic (neuropeptide Y/agouti-related protein; NPY/AgRP) and anorexigenic (proopiomelanocortin; POMC) neurons via an ATP-dependent mechanism. In vivo, activation of tanycytes triggered acute hyperphagia only in the fed state

APA, Harvard, Vancouver, ISO, and other styles

19

Sáenz de Miera, Cristina, Béatrice Bothorel, Catherine Jaeger, Valérie Simonneaux, and David Hazlerigg. "Maternal photoperiod programs hypothalamic thyroid status via the fetal pituitary gland." Proceedings of the National Academy of Sciences 114, no. 31 (2017): 8408–13. http://dx.doi.org/10.1073/pnas.1702943114.

Full text

Abstract:

In wild mammals, offspring development must anticipate forthcoming metabolic demands and opportunities. Within species, different developmental strategies may be used, dependent on when in the year conception takes place. This phenotypic flexibility is initiated before birth and is linked to the pattern of day length (photoperiod) exposure experienced by the mother during pregnancy. This programming depends on transplacental communication via the pineal hormone melatonin. Here, we show that, in the Siberian hamster (Phodopus sungorus), the programming effect of melatonin is mediated by the par

APA, Harvard, Vancouver, ISO, and other styles

20

Balland, Églantine, and Vincent Prévot. "Les tanycytes hypothalamiques." médecine/sciences 30, no. 6-7 (2014): 624–27. http://dx.doi.org/10.1051/medsci/20143006009.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Egri, P., C. Fekete, Á. Dénes, et al. "Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Regulates the Hypothalamo-Pituitary-Thyroid (HPT) Axis via Type 2 Deiodinase in Male Mice." Endocrinology 157, no. 6 (2016): 2356–66. http://dx.doi.org/10.1210/en.2016-1043.

Full text

Abstract:

The hypothalamic activation of thyroid hormones by type 2 deiodinase (D2), catalyzing the conversion of thyroxine to T3, is critical for the proper function of the hypothalamo-pituitary-thyroid (HPT) axis. Regulation of D2 expression in tanycytes alters the activity of the HPT axis. However, signals that regulate D2 expression in tanycytes are poorly understood. The pituitary adenylate cyclase-activating polypeptide (PACAP) increases intracellular cAMP level, a second messenger known to stimulate the DIO2 gene; however, its importance in tanycytes is not completely characterized. Therefore, we

APA, Harvard, Vancouver, ISO, and other styles

22

Rodríguez-Rodríguez, Adair, Rosa María Uribe, Antonieta Cote-Vélez, Patricia Joseph-Bravo, and Jean-Louis Charli. "Hypothalamic Median Eminence Thyrotropin-Releasing Hormone-Degrading Ectoenzyme Activity Is Dispensable for Basal Thyroid Axis Activity in Lean Rodents." Cells 14, no. 10 (2025): 725. https://doi.org/10.3390/cells14100725.

Full text

Abstract:

The amplitude of the phasic output of thyrotropin-releasing hormone (TRH) into the hypothalamus–pituitary portal capillaries is likely controlled by the TRH-degrading ectoenzyme (TRH-DE) expressed on the surface of median eminence (ME) β2-tanycytes. To extend this hypothesis, we performed experiments on adult rodents reared in standard conditions. TRH-DE was close to the putative sites of TRH release in the male rat external layer of the ME. In global Trhde knockout mice, basal hypothalamus–pituitary–thyroid (HPT) axis parameters were not altered but we detected an increased vimentin (a tanycy

APA, Harvard, Vancouver, ISO, and other styles

23

Müller-Fielitz, Helge, and Markus Schwaninger. "The Role of Tanycytes in the Hypothalamus-Pituitary-Thyroid Axis and the Possibilities for Their Genetic Manipulation." Experimental and Clinical Endocrinology & Diabetes 128, no. 06/07 (2019): 388–94. http://dx.doi.org/10.1055/a-1065-1855.

Full text

Abstract:

AbstractThyroid hormone (TH) regulation is important for development, energy homeostasis, heart function, and bone formation. To control the effects of TH in target organs, the hypothalamus-pituitary-thyroid (HPT) axis and the tissue-specific availability of TH are highly regulated by negative feedback. To exert a central feedback, TH must enter the brain via specific transport mechanisms and cross the blood-brain barrier. Here, tanycytes, which are located in the ventral walls of the 3rd ventricle in the mediobasal hypothalamus (MBH), function as gatekeepers. Tanycytes are able to transport,

APA, Harvard, Vancouver, ISO, and other styles

24

Ebling, Francis J. P., and Ricardo Samms. "Txnip, Tanycytes, and Torpor." Endocrinology 154, no. 6 (2013): 1970–72. http://dx.doi.org/10.1210/en.2013-1390.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Osterstock, Guillaume, Taoufik El Yandouzi, Nicola Romanò, et al. "Sustained Alterations of Hypothalamic Tanycytes During Posttraumatic Hypopituitarism in Male Mice." Endocrinology 155, no. 5 (2014): 1887–98. http://dx.doi.org/10.1210/en.2013-1336.

Full text

Abstract:

Traumatic brain injury is a leading cause of hypopituitarism, which compromises patients' recovery, quality of life, and life span. To date, there are no means other than standardized animal studies to provide insights into the mechanisms of posttraumatic hypopituitarism. We have found that GH levels were impaired after inducing a controlled cortical impact (CCI) in mice. Furthermore, GHRH stimulation enhanced GH to lower level in injured than in control or sham mice. Because many characteristics were unchanged in the pituitary glands of CCI mice, we looked for changes at the hypothalamic leve

APA, Harvard, Vancouver, ISO, and other styles

26

Prager-Khoutorsky, Masha, and Charles W. Bourque. "Anatomical organization of the rat organum vasculosum laminae terminalis." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 309, no. 4 (2015): R324—R337. http://dx.doi.org/10.1152/ajpregu.00134.2015.

Full text

Abstract:

The organum vasculosum of the laminae terminalis (OVLT) is a circumventricular organ located along the ventral part of the anterior wall of the third ventricle. Because it lacks a complete blood-brain barrier (BBB), blood-borne signals detected in the OVLT provide the brain with information from the periphery and contribute to the generation of centrally mediated responses to humoral feedback and physiological stressors. Experimental studies on the rat OVLT are hindered by a poor understanding of its precise anatomical dimensions and cellular organization. In this study, we use histological te

APA, Harvard, Vancouver, ISO, and other styles

27

Sullivan, Andrew I., Matthew J. Potthoff, and Kyle H. Flippo. "Tany-Seq: Integrated Analysis of the Mouse Tanycyte Transcriptome." Cells 11, no. 9 (2022): 1565. http://dx.doi.org/10.3390/cells11091565.

Full text

Abstract:

The ability to maintain energy homeostasis is necessary for survival. Recently, an emerging role for ependymogial cells, which line the third ventricle in the hypothalamus in the regulation of energy homeostasis, has been appreciated. These cells are called tanycytes and are physically at the interface of brain communication with peripheral organs and have been proposed to mediate the transport of circulating hormones from the third ventricle into the parenchyma of the hypothalamus. Despite the important role tanycytes have been proposed to play in mediating communication from the periphery to

APA, Harvard, Vancouver, ISO, and other styles

28

Dale, Nicholas, and Cameron Frayling. "Tanycytes emerge as hypothalamic chemosensors." Physiology News, Spring 2012 (April 1, 2012): 26–29. http://dx.doi.org/10.36866/pn.86.26.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Dietrich, Marcelo O., and Tamas L. Horvath. "Fat incites tanycytes to neurogenesis." Nature Neuroscience 15, no. 5 (2012): 651–53. http://dx.doi.org/10.1038/nn.3091.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Lazcano, Iván, Agustina Cabral, Rosa María Uribe, et al. "Fasting Enhances Pyroglutamyl Peptidase II Activity in Tanycytes of the Mediobasal Hypothalamus of Male Adult Rats." Endocrinology 156, no. 7 (2015): 2713–23. http://dx.doi.org/10.1210/en.2014-1885.

Full text

Abstract:

Fasting down-regulates the hypothalamus-pituitary-thyroid (HPT) axis activity through a reduction of TRH synthesis in neurons of the parvocellular paraventricular nucleus of the hypothalamus (PVN). These TRH neurons project to the median eminence (ME), where TRH terminals are close to the cytoplasmic extensions of β2 tanycytes. Tanycytes express pyroglutamyl peptidase II (PPII), the TRH-degrading ectoenzyme that controls the amount of TRH that reaches the anterior pituitary. We tested the hypothesis that regulation of ME PPII activity is another mechanism by which fasting affects the activity

APA, Harvard, Vancouver, ISO, and other styles

31

Elizondo-Vega, Roberto, Karina Oyarce, Magdiel Salgado, et al. "Inhibition of Hypothalamic MCT4 and MCT1–MCT4 Expressions Affects Food Intake and Alters Orexigenic and Anorexigenic Neuropeptide Expressions." Molecular Neurobiology 57, no. 2 (2019): 896–909. http://dx.doi.org/10.1007/s12035-019-01776-6.

Full text

Abstract:

Abstract Feeding behavior regulation is a complex process, which depends on the central integration of different signals, such as glucose, leptin, and ghrelin. Recent studies have shown that glial cells known as tanycytes that border the basal third ventricle (3V) detect glucose and then use glucose-derived signaling to inform energy status to arcuate nucleus (ARC) neurons to regulate feeding behavior. Monocarboxylate transporters (MCT) 1 and MCT4 are localized in the cellular processes of tanycytes, which could facilitate monocarboxylate release to orexigenic and anorexigenic neurons. We hypo

APA, Harvard, Vancouver, ISO, and other styles

32

Bellamy, Charlotte, Hannah Tovell, Florent Dingli, et al. "CSIG-30. FUNCTIONAL CHARACTERISATION OF A NOVEL MUTATION IN PRKCA, THE MAJOR DRIVER OF CHORDOID GLIOMAS." Neuro-Oncology 25, Supplement_5 (2023): v47. http://dx.doi.org/10.1093/neuonc/noad179.0186.

Full text

Abstract:

Abstract Chordoid gliomas (ChG) are a rare low-grade brain tumour, believed to be derived from Tanycytes. An analysis by the team previously identified a novel mutation present in all ChGs: PRKCA p.D463H. This mutation involves a D463H amino acid substitution at the kinase domain of the Protein kinase C alpha (PKCα) and represents the hallmark of ChG. PKCα is a serine/threonine kinase, that carries out the regulation of various functions in the cell. The aim of the project is to identify novel and biologically relevant PKCα D463H signalling pathways, which will demonstrate the involvement and

APA, Harvard, Vancouver, ISO, and other styles

33

Frayling, Cameron, Ruth Britton, and Nicholas Dale. "ATP-mediated glucosensing by hypothalamic tanycytes." Journal of Physiology 589, no. 9 (2011): 2275–86. http://dx.doi.org/10.1113/jphysiol.2010.202051.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Gao, Yuanqing, Matthias H. Tschöp, and Serge Luquet. "Hypothalamic Tanycytes: Gatekeepers to Metabolic Control." Cell Metabolism 19, no. 2 (2014): 173–75. http://dx.doi.org/10.1016/j.cmet.2014.01.008.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Severi, Ilenia, Marco Fosca, Georgia Colleluori, et al. "High-Fat Diet Impairs Mouse Median Eminence: A Study by Transmission and Scanning Electron Microscopy Coupled with Raman Spectroscopy." International Journal of Molecular Sciences 22, no. 15 (2021): 8049. http://dx.doi.org/10.3390/ijms22158049.

Full text

Abstract:

Hypothalamic dysfunction is an initial event following diet-induced obesity, primarily involving areas regulating energy balance such as arcuate nucleus (Arc) and median eminence (ME). To gain insights into the early hypothalamic diet-induced alterations, adult CD1 mice fed a high-fat diet (HFD) for 6 weeks were studied and compared with normo-fed controls. Transmission and scanning electron microscopy and histological staining were employed for morphological studies of the ME, while Raman spectroscopy was applied for the biochemical analysis of the Arc-ME complex. In HFD mice, ME β2-tanycytes

APA, Harvard, Vancouver, ISO, and other styles

36

Prévot, Vincent. "Brain infection by SARS-CoV-2: Lifelong consequences." Open Access Government 41, no. 1 (2024): 22–23. http://dx.doi.org/10.56367/oag-041-10397.

Full text

Abstract:

Brain infection by SARS-CoV-2: Lifelong consequences The WATCH team, founded to elucidate the role played by specialized brain cells called tanycytes in various physiological processes, has been investigating how and where the SARS-CoV-2 virus infects the brain, and some long-term consequences of this neuro-invasion. The European Research Council (ERC) Synergy project WATCH (Well-Aging and the Tanycytic Control of Health) brings together the teams of three principal investigators: Vincent Prevot, a neuroendocrinologist working for the French National Health Research Institute (INSERM) in Lille

APA, Harvard, Vancouver, ISO, and other styles

37

Przybylska-Piech, Anna S., Victoria Diedrich, and Annika Herwig. "Seasonal changes in activity of hypothalamic thyroid hormone system in different winter phenotypes of Djungarian hamster (Phodopus sungorus)." PLOS ONE 19, no. 10 (2024): e0309591. http://dx.doi.org/10.1371/journal.pone.0309591.

Full text

Abstract:

Although the Djungarian hamster (Phodopus sungorus) is a seasonality model, it presents substantial variability in winter acclimation. In response to short photoperiod, some individuals express a suite of winter traits such as low body mass, regressed gonads, white fur, and daily torpor, while others develop only some adjustments or maintain a summer phenotype. Despite comprehensive research, the mechanisms underlying polymorphism of winter phenotype are still unknown. We compared key elements of the hypothalamic thyroid hormone system, as well as the tanycyte architecture in hamsters of both

APA, Harvard, Vancouver, ISO, and other styles

38

Langlet, F. "Tanycytes: A Gateway to the Metabolic Hypothalamus." Journal of Neuroendocrinology 26, no. 11 (2014): 753–60. http://dx.doi.org/10.1111/jne.12191.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Elizondo‐Vega, Roberto, Christian Cortes‐Campos, Maria J. Barahona, Karina A. Oyarce, Claudio A. Carril, and Maria A. García‐Robles. "The role of tanycytes in hypothalamic glucosensing." Journal of Cellular and Molecular Medicine 19, no. 7 (2015): 1471–82. http://dx.doi.org/10.1111/jcmm.12590.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Langlet, Fanny. "Targeting Tanycytes: Balance between Efficiency and Specificity." Neuroendocrinology 110, no. 7-8 (2020): 574–81. http://dx.doi.org/10.1159/000505549.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Ebling, Francis J. P., and Jo E. Lewis. "Tanycytes and hypothalamic control of energy metabolism." Glia 66, no. 6 (2018): 1176–84. http://dx.doi.org/10.1002/glia.23303.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Dardente, Hugues. "HYPOTHALAMIC TANYCYTES ARE INVOLVED IN SEASONAL FUNCTIONS." IBRO Neuroscience Reports 15 (October 2023): S52. http://dx.doi.org/10.1016/j.ibneur.2023.08.2159.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Prevot, Vincent, Markus Schwaninger, and Ruben Nogueiras. "The WATCH project: Tanycytes in health and disease." Open Access Government 37, no. 1 (2023): 132–33. http://dx.doi.org/10.56367/oag-037-10410.

Full text

Abstract:

The WATCH project: Tanycytes in health and disease In our aging societies, maintaining health and limiting age-related metabolic or cognitive disorders are of primordial importance not only for the well-being of the individual but also from the economic and societal points of view. The Synergy project Well-Aging and the Tanycytic Control of Health (WATCH), funded by the European Research Council (ERC), is a high-impact project conducted by Vincent Prévot, a neuroendocrinologist working for the French national health research institute (Inserm), in Lille, France; Markus Schwaninger, a neurologi

APA, Harvard, Vancouver, ISO, and other styles

44

Givalois, Laurent, Sandor Arancibia, Gérard Alonso, and Lucia Tapia-Arancibia. "Expression of Brain-Derived Neurotrophic Factor and Its Receptors in the Median Eminence Cells with Sensitivity to Stress." Endocrinology 145, no. 10 (2004): 4737–47. http://dx.doi.org/10.1210/en.2004-0616.

Full text

Abstract:

Abstract The median eminence (ME) is considered as the final common pathway connecting the nervous and endocrine systems. In this neurohemal structure, dynamic interactions among nerve terminals, tanycytes, and astrocytes determine through plastic processes the neurohormones access to the portal blood. Because brain-derived neurotrophic factor (BDNF) is involved in plastic changes, we investigated its presence and that of its receptors (TrkB) in the different cellular types described in the ME. Using in situ hybridization and immunohistochemical techniques, we demonstrated that BDNF immunoreac

APA, Harvard, Vancouver, ISO, and other styles

45

de Vries, E. M., S. Nagel, R. Haenold та ін. "The Role of Hypothalamic NF-κB Signaling in the Response of the HPT-Axis to Acute Inflammation in Female Mice". Endocrinology 157, № 7 (2016): 2947–56. http://dx.doi.org/10.1210/en.2016-1027.

Full text

Abstract:

A large proportion of critically ill patients have alterations in the hypothalamus-pituitary-thyroid (HPT) axis, collectively known as the nonthyroidal illness syndrome. Nonthyroidal illness syndrome is characterized by low serum thyroid hormone (TH) concentrations accompanied by a suppressed central component of the HPT axis and persistent low serum TSH. In hypothalamic tanycytes, the expression of type 2 deiodinase (D2) is increased in several animal models of inflammation. Because D2 is a major source of T3 in the brain, this response is thought to suppress TRH expression in the paraventric

APA, Harvard, Vancouver, ISO, and other styles

46

Barahona, María Jose, Luciano Ferrada, and Francisco Nualart. "TANYCYTES-ASSOCIATED G6PASE SYSTEM CONTROL THE ENERGY BALANCE." IBRO Neuroscience Reports 15 (October 2023): S213. http://dx.doi.org/10.1016/j.ibneur.2023.08.340.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Bjelke, Börje, та Kjell Fuxe. "Intraventricular β-endorphin accumulates in DARPP-32 immunoreactive tanycytes". NeuroReport 5, № 3 (1993): 265–68. http://dx.doi.org/10.1097/00001756-199312000-00021.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Böttcher, Mareike, Helge Müller-Fielitz, Sivaraj M. Sundaram та ін. "NF-κB signaling in tanycytes mediates inflammation-induced anorexia". Molecular Metabolism 39 (вересень 2020): 101022. http://dx.doi.org/10.1016/j.molmet.2020.101022.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Dale, Nicholas. "Purinergic signaling in hypothalamic tanycytes: Potential roles in chemosensing." Seminars in Cell & Developmental Biology 22, no. 2 (2011): 237–44. http://dx.doi.org/10.1016/j.semcdb.2011.02.024.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

RODRIGUEZ, E., J. BLAZQUEZ, F. PASTOR, et al. "Hypothalamic Tanycytes: A Key Component of Brain–Endocrine Interaction." International Review of Cytology 247 (2005): 89–164. http://dx.doi.org/10.1016/s0074-7696(05)47003-5.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!