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Journal articles on the topic 'Taraxasteryl Acetate'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Reynolds, William F., Jeffery F. Sawyer, Raúl G. Enriquez, Laura I. Escobar, Marco A. Chavez, and James N. Shoolery. "Total assignment of the 13C spectrum of taraxasteryl acetate by 13C–13C connectivity experiments and determination of the stereochemistry of taraxasterol by X-ray diffraction." Canadian Journal of Chemistry 63, no. 5 (1985): 1048–54. http://dx.doi.org/10.1139/v85-178.

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13C–13C connectivity (INADEQUATE) experiments have been used to reassign the 13C spectrum of taraxasteryl acetate. This shows that there were ten errors in an earlier 13C spectral assignment for this compound. An X-ray diffraction investigation of taraxasterol shows that ring E adopts a slightly distorted boat conformation. It is suggested that severe steric interactions in the chair form force it to adopt this unusual conformation. On the basis of the 1H–1H coupling constants, it is concluded that taraxasteryl acetate adopts a very similar conformation in solution. Crystals of taraxasterol–et

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2

U.K., SOM, K. SIL A., B. HAQUE K., and P. DUTTA C. "Oxidation Products of Taraxasteryl Acetate and Molecular Rearrangement of its Epoxide." Journal of Indian Chemical Society Vol. 65, Aug 1988 (1988): 604–6. https://doi.org/10.5281/zenodo.6348801.

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Department of Chemistry, <em>University </em>College of Science, 92 A. P. C. Road, Calcutta-700 009 <em>Manuscript received 31 March 1987, revised 2 March 2988,accepted 3 June 1988</em> Oxidation Products of Taraxasteryl Acetate and Molecular Rearrangement of its Epoxide.

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3

U.K., SOM, K. SIL A., E. HAQUE K., P. DUTTA C., and DHARA K.P. "Oxidation Products of Taraxasteryl Acetate and Molecular Rearrancement of its Epoxide." Journal of Indian Chemical Society Vol. 65, Aug 1998 (1988): 602–4. https://doi.org/10.5281/zenodo.6076257.

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Department of Chemistry, University of Kalyani, Kalyani-741 235 Department of Chemistry, <em>University </em>College of Science, 92 A. P. C. Road, Calcutta-700 009 <em>Manuscript received 31 March 1987, revised 2 March 2988, accepted 3 June 1988</em> <em>Oxidation Products of Taraxasteryl Acetate and Molecular Rearrancement of its Epoxide </em>

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4

Reynolds, William, and Raul Enriquez. "Concerning the Recently Reassigned13C-NMR Spectrum of Taraxasteryl Acetate." Planta Medica 62, no. 05 (1996): 484. http://dx.doi.org/10.1055/s-2006-957952.

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5

Iijima, Koji, Hiroaki Kiyohara, Morihisa Tanaka, Tsukasa Matsumoto, Jong-Chol Cyong, and Haruki Yamada. "Preventive Effect of Taraxasteryl Acetate fromInula britannicasubsp.japonicaon Experimental Hepatitisin vivo." Planta Medica 61, no. 01 (1995): 50–53. http://dx.doi.org/10.1055/s-2006-957998.

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6

Khalilova, A. Z., I. A. Litvinov, D. V. Beskrovnyi, et al. "Isolation and Crystal Structure of Taraxasteryl Acetate from Onopordum acanthium." Chemistry of Natural Compounds 40, no. 3 (2004): 254–57. http://dx.doi.org/10.1023/b:conc.0000039135.20844.8e.

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Bahadır-Acıkara, Özlem, Serkan Özbilgin, Gülcin Saltan-İşcan, et al. "Phytochemical Analysis of Podospermum and Scorzonera n-Hexane Extracts and the HPLC Quantitation of Triterpenes." Molecules 23, no. 7 (2018): 1813. http://dx.doi.org/10.3390/molecules23071813.

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Previously tested n-hexane extracts of the Scorzonera latifolia showed promising bioactivity in vivo. Because triterpenes could account for this activity, n-hexane extracts were analyzed by HPLC to identify and quantify the triterpenes as the most abundant constituents. Other Scorzonera and Podospermum species, potentially containing triterpenic aglycones, were included in the study. An HPLC method for simultaneous determination of triterpene aglycones was therefore developed for analysis of Podospermum and Scorzonera species. n-Hexane extracts of root and aerial parts of S. latifolia, ten oth

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8

Pérez-García, F., E. Marín, T. Parella, T. Adzet, and S. Cañigueral. "Activity of taraxasteryl acetate on inflammation and heat shock protein synthesis." Phytomedicine 12, no. 4 (2005): 278–84. http://dx.doi.org/10.1016/j.phymed.2004.03.008.

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9

Wu, Jianhao, Jialin Sun, Meiqi Liu, et al. "Botany, Traditional Use, Phytochemistry, Pharmacology and Quality Control of Taraxaci herba: Comprehensive Review." Pharmaceuticals 17, no. 9 (2024): 1113. http://dx.doi.org/10.3390/ph17091113.

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Taraxaci herba, as a traditional Chinese medicine, is the name of the Taraxacum genus in the Asteraceae family. Documented in the Tang Herbal Medicine (Tang Dynasty, AD 657–659), its medicinal properties cover a wide range of applications such as acute mastitis, lung abscess, conjunctival congestion, sore throat, damp-heat jaundice, and vision improvement. In the Chinese Pharmacopoeia (Edition 2020), more than 40 kinds of China-patented drugs containing Taraxaci herba were recorded. This review explores the evolving scientific understanding of Taraxaci herba, covering facets of ethnopharmacolo

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Kirimer, Neş'e, Zeynep Tunalier, K. Can Başer, and Ipek Cingi. "Antispasmodic and Spasmogenic Effects ofScolymus hispanicusand Taraxasteryl Acetate on Isolated Ileum Preparation." Planta Medica 63, no. 06 (1997): 556–58. http://dx.doi.org/10.1055/s-2006-957765.

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11

Ivanov, Ivan, Nadezhda Petkova, Julian Tumbarski, et al. "GC-MS characterization of n-hexane soluble fraction from dandelion (Taraxacum officinale Weber ex F.H. Wigg.) aerial parts and its antioxidant and antimicrobial properties." Zeitschrift für Naturforschung C 73, no. 1-2 (2018): 41–47. http://dx.doi.org/10.1515/znc-2017-0107.

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AbstractA comparative investigation of n-hexane soluble compounds from aerial parts of dandelion (Taraxacum officinaleWeber ex F.H. Wigg.) collected during different vegetative stages was carried out. The GC-MS analysis of the n-hexane (unpolar) fraction showed the presence of 30 biologically active compounds. Phytol [14.7% of total ion current (TIC)], lupeol (14.5% of TIC), taraxasteryl acetate (11.4% of TIC), β-sitosterol (10.3% of TIC), α-amyrin (9.0% of TIC), β-amyrin (8.3% of TIC), and cycloartenol acetate (5.8% of TIC) were identified as the major components in n-hexane fraction. The unp

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Boğa, Mehmet, Pelin Köseoğlu Yılmaz, Deniz Barıș Cebe, Mashhad Fatima, Bina S. Siddiqui, and Ufuk Kolak. "Chemical Constituents and Biological Activities of Cirsium leucopsis, C. sipyleum, and C. eriophorum." Zeitschrift für Naturforschung C 69, no. 9-10 (2014): 381–90. http://dx.doi.org/10.5560/znc.2014-0071.

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Abstract Two endemic Cirsium species, C. leucopsis DC. and C. sipyleum O. Schwarz, and C. eriophorum (L.) Scop. growing in Turkey were investigated to establish their secondary metabolites, fatty acid compositions, and antioxidant and anticholinesterase potentials. Spectroscopic methods were used to elucidate the structures of thirteen known compounds (p-hydroxy-benzoic acid, vanillic acid, cisepoxyconiferyl alcohol, syringin, balanophonin, 1′-O-methyl-balanophonin, apigenin, kaempferol-3- O-β-D-glucopyranoside, kaempferol-3-O-α-L-rhamnopyranoside, taraxasterol, taraxasterol acetate, β-sitoste

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Sing, Bupinder, S. N. Ram, V. B. Pandey, V. K. Joshi, and S. S. Gambhir. "Studies on antiinflammatory activity of taraxasterol acetate fromEchinops echinatus in rats and mice." Phytotherapy Research 5, no. 3 (1991): 103–6. http://dx.doi.org/10.1002/ptr.2650050303.

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14

Trendafilova, Antoaneta, Victoria Ivanova, Milka Todorova, Plamena Staleva, and Ina Aneva. "Terpenoids in four Inula species from Bulgaria." Journal of the Serbian Chemical Society 86, no. 12 (2021): 1229–40. http://dx.doi.org/10.2298/jsc210730087t.

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Phytochemical study of the chloroform extract of the aerial parts of Inula germanica L., I. ensifolia L., I. conyza (Griess.) DC. and I. salicina L. led to the identification of 33 terpenoids. ?- and ?-amyrin, lupeol, taraxasterol, ?-taraxasterol and their 3-O-acetates and 3-O-palmitates were identified by GC/MS. In addition, the structures of 3-O-palmitates of mainaladiol, arnidiol, faradiol and 16-hydroxylupeol were confirmed by NMR. ent-Kaur-16-en-19- -oic acid and its 15?-(3-methylpentanoyloxy) and 15?-(3-methylbutanoyloxy) derivatives were isolated from I. conyza. Ten closely related sesq

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15

Polatoğlu, Kaan, Ömer Cem Karakoç, Fatih Demirci, Ayhan Gökçe, and Nezhun Gören. "Chemistry and Biological Activities of Tanacetum chiliophyllum var. oligocephalum Extracts." Journal of AOAC INTERNATIONAL 96, no. 6 (2013): 1222–27. http://dx.doi.org/10.5740/jaoacint.sgepolatoglu.

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Abstract Tanacetum chiliophyllum (Fisch. & Mey.) var. oligocephalum (D.C.) Sosn. collected in Turkey was subjected to phytochemical and biological evaluations in this study. Pure compounds were obtained from ethyl acetate extracts of the stems of the plant material. Structures of isolated compounds were determined using spectral methods. Seven known flavones, i.e., 5-hydroxy-3′,4′,6,7-tetramethoxyflavone, eupatilin (6-hydroxyluteolin-6,3′,4′-trimethylether), cirsimaritin (scuttellarin-6,7-dimethylether), cirsilineol, 5–hydroxy-3′,4′,7-trimethoxy flavone, desmethoxy-centaureidin, and jaceos

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Xu, Chen, Hai-Yang Jia, Bo Zuo, et al. "Chemical Constituents of the Aerial Parts of Euphorbia Nematocypha." Natural Product Communications 11, no. 2 (2016): 1934578X1601100. http://dx.doi.org/10.1177/1934578x1601100210.

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Chemical constituents of the dried aerial parts of Euphorbia nematocypha were investigated. A new oleanane triterpenoid, trans, trans-2′,4′-hexadienedioicacid-1′-β-amyrin ester (1), together with, β-amyrin (2), β-amyrin acetate (3), betulinic acid (4), ellagic acid (5), oleanolic acid (6), β-sitosterol (7), kaempferol (8), quercetin (9), lupeol (10) and pseudo-taraxasterol (11) were isolated from the methylene chloride extract. Their structures were elucidated on the basis of extensive spectroscopic (1D- & 2D-NMR) and ESI-MS analysis and comparison with data reported in the literature. The

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17

Trendafilova, Antoaneta, Milka Todorova, Nikolina Kutova, and Maya Guncheva. "Phytochemical Profile and Anti-lipase Activity of Balkan Endemic Jurinea tzar-ferdinandii." Natural Product Communications 13, no. 8 (2018): 1934578X1801300. http://dx.doi.org/10.1177/1934578x1801300823.

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Phytochemical study of the Balkan endemic J. tzar-ferdinandii Davidov allowed the identification of twenty-two components. β-Amyrin, lupeol, taraxasterol and Ψ-taraxasterol and their 3- O-acetates and 3- O-palmitates were identified by GC/MS. Six closely related sesquiterpene lactones and four flavones were isolated from the chloroform extract using column chromatography, and their structural identification was performed by spectral analyses. All isolated compounds are described for the first time in Jurinea species. The inhibitory potential of the total chloroform extract, fractions containin

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18

Irianti, Tatang, Sylvia Utami Tanjung Pratiwi, and Intan Farida Yasmin. "Antituberculosis Activity of Active Compound of Ethyl Acetate Extract for Patikan Kebo (Euphorbia hirta L.)." Jordan Journal of Pharmaceutical Sciences 15, no. 4 (2022): 461–73. http://dx.doi.org/10.35516/jjps.v15i4.671.

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Infectious diseases caused by bacteria are a concern in the world of health. The microbe Mycobacterium tuberculosis which causes tuberculosis (TB) is one of the main disease problems in the world, as evidenced by the existence of 10.4 million sufferers and 1.8 million deaths in the world in 2015. During 5 years (2015 to 2020), the World Health Organization was done some comprehensive programs it can reduce mortality up to 13%. However, since early 2020 were increased the mortality rate again as in 2015. In addition, the increasing incidence of bacterial resistance to antibiotics has triggered

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19

Elsharkawy, Eman, Mona Elshathely, Gehad Abdel Jaleel, and Haya Ibrahim Al-Johar. "Anti-inflammatory effects of medicinal plants mixture used by Bedouin people in Saudi Arabia." Herba Polonica 59, no. 3 (2013): 76–87. http://dx.doi.org/10.2478/hepo-2013-0018.

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Abstract Due to toxic and adverse side effects of synthetic drugs, traditional herbal medicine has the potential as a source of new bioactive molecules. That is why we investigated this research, searching new anti-inflammatory drugs from plants growing around us. The anti-inflammatory effect of the mixture of different plants used in traditional medicine (Alkanna tinctoria, Rubia tinctorum and Artemisia herba alba) were studied using carrageenan-induced paw edema (oil mixture extract 100 mg/kg and 200 mg/kg). These material reduces carrageenan-induced inflammation in rats and shows inhibition

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20

Rufai, Y., N. Basar, and A. Sani. "Optimization and Isolation of 4,8,12,16-Tetramethylheptadecan-4-olide from Deinbollia pinnata." Asian Journal of Chemistry 31, no. 11 (2019): 2503–11. http://dx.doi.org/10.14233/ajchem.2019.22165.

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Manual agitation on ultrasonic assisted extraction process, fractionation, isolation and purification afforded 4,8,12,16-tetramethylheptadecan-4-olide (1) along with 11 compounds 2-12 i.e., squalene (2), phytyl palmitate (3), lupeol (4), taraxasterol (5), myristic acid (6), palmitic acid (7), campesterol (8), stigmasterol (9), λ-sitosterol (10), stigmastan-3, 5-diene (11) and stigmasta-5,22-diene-3-ol acetate (12). Their structures were elucidated spectroscopically (2D NMR, IR, GC-MS and 1D NMR). The optimal conditions for high yield of extracts were obtained at 45 °C, after 35 min and solvent

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Sahli, Ramla, Céline Rivière, Cédric Dufloer, et al. "Antiproliferative and Antibacterial Activities of Cirsium scabrum from Tunisia." Evidence-Based Complementary and Alternative Medicine 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/7247016.

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Several Cirsium species are known for their uses in traditional medicine and consequently are studied for their phytochemical content and their biological activities. In the framework of a previous study conducted on eight extremophile plants from Tunisia, we highlighted that the crude methanolic extract of C. scabrum, a not investigated thistle, showed moderate but quite selective cytotoxic activity against the cancerous cell line J774 compared to the noncancerous cell line WI38 (IC50 = 11.53 μg/ml on J774, IC50 = 29.89 µg/ml on WI38, and selectivity index = 2.6). In the current study, the pa

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Jalindar, Miss Chole Laxmi. "Prapration of Tablet from Pencil Cactus for Treatment of Piles by Direct Compression method." International Journal for Research in Applied Science and Engineering Technology 9, no. 12 (2021): 1666–70. http://dx.doi.org/10.22214/ijraset.2021.39597.

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Abstract: The intention of current review is to make available upto-date information on morphology, ecological biodiversity, medicinal uses, phytochemistry and pharmacological activities on different parts of Euphorbia tirucalli (E. tirucalli). This plant has a number of medicinal uses. Latex of E. tirucalli is vesicant and rubefacient which is used for rheumatism, warts, cough, asthma, ear-ache, tooth-ache and neuralgia. It acts as a purgative in small doses while in big doses it is bitter irritant and emetic. Milky juice is alexiteric, carminative and purgative. It is useful in whooping coug

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Sweilam, Sherouk Hussein, Fatma M. Abdel Bar, Ahmed I. Foudah, et al. "Phytochemical Investigation, Antiulcer, Cyclooxygenase-2, and 15-Lipoxygenase Inhibitory Activities of Echinops erinaceus Kit Tan." Separations 10, no. 2 (2023): 76. http://dx.doi.org/10.3390/separations10020076.

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Plants of the genus Echinop (Asteraceae) are traditional medicinal plants used to treat several GIT ailments, owing to their diverse bioactive secondary metabolites, including sesquiterpenoids, triterpenoids, phytosterols, phenolics, flavonoids, alkaloids, and essential oils. Echinops erinaceus Kit Tan is a wild perennial herb of the genus Echinops which is endemic to Oman, Saudi Arabia, and Yemen. Currently, there are no previous reports exploring its anti-ulcer and anti-inflammatory effects. Additionally, few reports have described the chemical profile of E. erinaceus Kit Tan. In the current

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Shah, Muddaser, Waheed Murad, Najeeb Ur Rehman, et al. "Biomedical Applications of Scutellaria edelbergii Rech. f.: In Vitro and In Vivo Approach." Molecules 26, no. 12 (2021): 3740. http://dx.doi.org/10.3390/molecules26123740.

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In the current study, in vitro antimicrobial and antioxidant activities and in vivo anti-inflammatory and analgesic activities of Scutellaria edelbergii Rech. f. (crude extract and subfractions, i.e., n-hexane, ethyl acetate (EtOAc), chloroform, n-butanol (n-BuOH) and aqueous) were explored. Initially, extraction and fractionation of the selected medicinal plant were carried out, followed by phytochemical qualitative tests, which were mostly positive for all the extracts. EtOAc fraction possessed a significant amount of phenolic (79.2 ± 0.30 mg GAE/g) and flavonoid (84.0 ± 0.39 mg QE/g) conten

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Mohammed, Hamdoon A., Mohammed F. Abdelwahab, El-Sayed M. El-Ghaly, and Ehab A. Ragab. "Phytochemical Characterization, In Vitro Anti-Inflammatory, Anti-Diabetic, and Cytotoxic Activities of the Edible Aromatic Plant; Pulicaria jaubertii." Molecules 26, no. 1 (2021): 203. http://dx.doi.org/10.3390/molecules26010203.

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Pulicaria jaubertii is a medicinal herb that alleviates inflammations and fever. Chromatographic separation, phytochemical characterization, and in vitro biological activities of the plant n-hexane extract were conducted for the first time in this study. Six compounds were isolated for the first time from the n-hexane fraction of Pulicaria jaubertii aerial parts and were identified on the bases of NMR and MS analyses as pseudo-taraxaterol (1), pseudo-taraxasterol acetate (2), 3β-acetoxytaraxaster-20-en-30-aldehyde (3), calenduladiol-3-O-palmitate (4), stigmasterol (5), and α-tocospiro B (6). C

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Lad, Snehal, Priya S. Rao, and Dattaprasad N Vikhe. "Calotropis gigantea- A Review." Research Journal of Science and Technology, December 22, 2021, 261–64. http://dx.doi.org/10.52711/2349-2988.2021.00041.

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Calotropis gigantea plant has a family Asclepiadaceae commonly and sub family Apocynaceae known as Madar in Hindi. It is a perennial herb with a very long history of use in traditional medicines. Calotropis gigantea is a hoary, laticiferous shrub, which is also known as “the milkweed”. Calotropis is used as a traditional medicinal plant in whole world. Calotropis gigantea plant contain chemical constituents in which cardenolides, flavonoids, terpenes, pregnanes and nonprotein amino acid and more in various concentration. The root bark contains α-amyrin, β-amyrin, taraxasterol and its ψ-isomer

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Choi, Han Suk, Jung Yeon Han, Eun Ju Cheong та Yong Eui Choi. "Characterization of a Pentacyclic Triterpene Acetyltransferase Involved in the Biosynthesis of Taraxasterol and ψ-Taraxasterol Acetates in Lettuce". Frontiers in Plant Science 12 (3 січня 2022). http://dx.doi.org/10.3389/fpls.2021.788356.

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Triterpenoids exist in a free state and/or in conjugated states, such as triterpene glycosides (saponins) or triterpene esters. There is no information on the enzyme participating in the production of triterpene esters from free triterpenes. Lettuce (Lactuca sativa) contains various pentacyclic triterpene acetates (taraxasterol acetates, ψ-taraxasterol acetates, taraxerol acetates, lupeol acetates, α-amyrin acetates, β-amyrin acetates, and germanicol acetate). In this study, we report a novel triterpene acetyltransferase (LsTAT1) in lettuce involved in the biosynthesis of pentacyclic triterpen

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Thi Viet Huong, Do, Phan Minh Giang, Hoang Thi Sim, and Truong Thi To Chinh. "Triterpenoids and Phytosterols Isolated from Pluchea Indica L. Leaves." VNU Journal of Science: Natural Sciences and Technology 35, no. 2 (2019). http://dx.doi.org/10.25073/2588-1140/vnunst.4910.

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Abstract: Taraxasterol acetate, 1-dotriacontanol, taraxasterol, stigmasterol, 2-(prop-1-ynyl)-5-(5,6-dihyroxyhexa-1,3-diynyl)thiophene), stigmasterol 3-O-β-D-glucopyranoside, and β-sitosterol 3-O-β-D-glucopyranoside were isolated from the leaves of Pluchea indica and determined with NMR techniques. Taraxasterol acetate, taraxasterol, and stigmasterol could be isolated in high yields from Pluchea indica growing in Gia Lam, Hanoi, Vietnam.  Keywords: Pluchea indica, phytosterol, triterpenoid, taraxasterol, stigmasterol. References: [1] Đỗ Tất Lợi, Những cây thuốc và vị thuốc Vi

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Yakubu, R., N. Basar, and K. Suleiman. "ANTI-INFLAMMATORY ACTIVITY OF DEINBOLLIA PINNATA LEAVES WITH ISOLATION OF TRITERPENOIDS." Journal of Chemical Society of Nigeria 48, no. 4 (2023). http://dx.doi.org/10.46602/jcsn.v48i4.912.

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Inflammation is the secondary signal from tissue/cell injury or damage. Most often have increased temperature, and blood flow and are characterized by pain, coloration and swelling. Leaves of Deinbollia pinnata have been into use for anti-inflammatory diseases in rural populated areas of African countries by barefoot doctors. The leaves of D. pinnata investigated showed higher anti-inflammatory with methanol, ethyl acetate and n-hexane in order of (80%, 50% and 14%) at 50 µL for bovine serum albumin assay; and methanol, ethyl acetate and n-hexane (85%, 57%, and 20%) at 40 µL using egg albumin

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Tang, Chao-Tao, Jing Yang, Zi-De Liu, Youxiang Chen, and Chunyan Zeng. "Taraxasterol acetate targets RNF31 to inhibit RNF31/p53 axis-driven cell proliferation in colorectal cancer." Cell Death Discovery 7, no. 1 (2021). http://dx.doi.org/10.1038/s41420-021-00449-5.

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AbstractColorectal cancer (CRC) is the third most common cancer worldwide. Several studies have suggested that taraxasterol acetate (TA) can inhibit the growth of tumor cells. However, to date, it remains unclear how TA inhibits cell growth and how RNF31 functions as an oncogene. We examined the expression of RNF31 in CRC tissue samples via immunohistochemistry and elucidated the function of RNF31 in CRC cells by constructing a cell model with RNF31 depletion. A cycloheximide (CHX)-chase analysis and immunofluorescence assays were conducted to demonstrate that TA can promote RNF31 degradation

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Khan, Muluh Emmanuel, Chijioke Ezekiel Elum, Augustina Onyebuchi Ijeomah, et al. "Isolation, Characterization, Antimicrobial and Theoretical Investigation of Some Bioactive Compounds Obtained from the Bulbs of Calotropisprocera." Journal of the Nigerian Society of Physical Sciences, August 1, 2023, 1576. http://dx.doi.org/10.46481/jnsps.2023.1576.

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This study characterizes the bioactive molecules from the bulb of Calotropisprocera and investigates the antimicrobial activities of the crude extracts. Theoretical studies on the two isolated compounds in the crude extract were also accomplished.The bulbs were air dried, pulverized, and subjected to extraction procedures by maceration using 500 mL each of normal-hexane, ethyl acetate and methanol. The crude extracts were further tested onmicroorganisms and phytochemical screening using standard procedures. In addition, the bioactive compounds in the extract were screened against DNA gyrase of

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Ghazanfary, Samereh, Mohsen Rahmanian, Mehran Vatanchian, Ali Haghbin, Farzaneh Shakeri, and Fatemeh Oroojalian. "Characterization and Efficacy Evaluation of mPEG-PLGA/Taraxasterol Acetate Nanoparticles as Nano-Therapeutic Agents in Asthma Management." BioNanoScience 15, no. 1 (2024). https://doi.org/10.1007/s12668-024-01677-6.

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Jin, Li, Man Li, Beihui He, et al. "Taraxasterol Acetate From Taraxacum officinale Ameliorates Dextran Sulfate Sodium–Induced Ulcerative Colitis in Mice in Association With Changes of the Metabolism and Structure of Gut Microbiota." Food Frontiers, November 25, 2024. http://dx.doi.org/10.1002/fft2.518.

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ABSTRACTUlcerative colitis (UC) is closely associated with the structural and metabolic disorders of gut microbiota. Taraxasterol acetate (TSA) from Taraxacum officinale (TO) has anti‐inflammatory activity. In this study, to investigate the therapeutic potential of TSA and its mechanism of action in dextran sulfate sodium (DSS)‐induced UC. The anti‐inflammatory effects of TSA were evaluated in vitro. DSS‐induced UC animal models and TSA gavage were employed for in vivo experiments. The results indicated that TSA showed good anti‐inflammatory effects both in vitro and in vivo, and the anti‐UC e

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Rodrigues, Maria Angélica Melo, and Elisandra Scapin. "CARACTERIZAÇÃO QUÍMICA E ATIVIDADE ANTIOXIDANTE DOS EXTRATOS DA CASCA da Cariniana rubra Gardner ex Miers." DESAFIOS - Revista Interdisciplinar da Universidade Federal do Tocantins 2, no. 1 (2023). http://dx.doi.org/10.20873/pibic2022_7.

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O presente estudo teve como objetivo realizar uma caracterização química e a avaliar a atividade antioxidante do extrato da entrecasca da Cariniana rubra Gardner ex Miers. A extração foi realizada em extrator soxhlet, com solvente hidroetanólico (70%), obtendo-se o extrato bruto (EB). Na caracterização química foi realizada a análise fitoquímica, Cromatografia Gasosa acoplada a Espectrometria de Massa (GC-MS) e Cromatografia Líquida com detector de Arranjo de Diodo (LC-PDA). Quantificou-se o teor de fenólicos, flavonoides e taninos totais, analisando também o seu potencial antioxidante pelo mé

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Araújo, Clináscia Rodrigues Rocha, Thiago de Melo Silva, Michaelle Geralda dos Santos, et al. "Anti-inflammatory and cytotoxic activities of the extracts, fractions, and chemical constituents isolated from Luehea ochrophylla Mart." BMC Complementary and Alternative Medicine 19, no. 1 (2019). http://dx.doi.org/10.1186/s12906-019-2701-7.

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Abstract Background Stem bark of Luehea ochrophylla (L. ochrophylla) is used by the traditional Brazilian medicine for treatment of rheumatic diseases and tumors. This study aimed to investigate inhibition of acute and chronic inflammations and cytotoxic activity of extracts, fractions, and isolated compounds from L. ochrophylla. Methods Hexane (HE) and ethanol (EE) extracts obtained from stem bark of L. ochrophylla were submitted to chromatographic fractionation. In order to test acute inflammation, experimental model of impact injury was used, followed by transdermal application of gels usin

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