Academic literature on the topic 'Targeted Delivery Vehicles'

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Journal articles on the topic "Targeted Delivery Vehicles"

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Laakkonen, Pirjo, and Kirsi Vuorinen. "Homing peptides as targeted delivery vehicles." Integrative Biology 2, no. 7-8 (2010): 326–37. http://dx.doi.org/10.1039/c0ib00013b.

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Backer, Marina V., Renee Aloise, Kristen Przekop, Konstantin Stoletov, and Joseph M. Backer. "Molecular Vehicles for Targeted Drug Delivery." Bioconjugate Chemistry 13, no. 3 (2002): 462–67. http://dx.doi.org/10.1021/bc0155770.

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Haq M, Misbah Ul. "Revolutionizing Drug Delivery: Targeted Approaches and Innovations for Effective Treatment." Pharmaceutical Drug Regulatory Affairs Journal 6, no. 1 (2023): 1–8. http://dx.doi.org/10.23880/pdraj-16000138.

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Targeted drug delivery, also referred to as intelligent drug delivery, is a therapeutic approach that aims to enhance drug concentration in specific regions of the body relative to others. There are two strategies employed to target drugs to specific organs or tissues: passive targeting and active targeting. Drug delivery vehicles are utilized to transport the medication to the desired location. An ideal drug delivery vehicle should have the ability to overcome barriers such as the blood-brain barrier. Conventional drug delivery systems distribute drugs throughout the body via the bloodstream,
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Wen, Yuting, Hongzhen Bai, Jingling Zhu, Xia Song, Guping Tang, and Jun Li. "A supramolecular platform for controlling and optimizing molecular architectures of siRNA targeted delivery vehicles." Science Advances 6, no. 31 (2020): eabc2148. http://dx.doi.org/10.1126/sciadv.abc2148.

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It requires multistep synthesis and conjugation processes to incorporate multifunctionalities into a polyplex gene vehicle to overcome numerous hurdles during gene delivery. Here, we describe a supramolecular platform to precisely control, screen, and optimize molecular architectures of siRNA targeted delivery vehicles, which is based on rationally designed host-guest complexation between a β-cyclodextrin–based cationic host polymer and a library of guest polymers with various PEG shape and size, and various density of ligands. The host polymer is responsible to load/unload siRNA, while the gu
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Suresh, Dhananjay, Brian Jenkins, Ajit Zambre, Anandhi Upendran, and Raghuraman Kannan. "Systematic Evaluation of Protein-Based Nanoparticles for Stable Delivery of Small Interfering RNA." Journal of Biomedical Nanotechnology 16, no. 7 (2020): 1169–81. http://dx.doi.org/10.1166/jbn.2020.2953.

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Developing a delivery vehicle to protect siRNA from degradation is a significant challenge. To solve this challenge, researchers attempted to use protein-based nanoparticles to deliver siRNA with limited to moderate success. However, a systematic investigation of comparing the ability of different protein-based nanoparticles as vehicles to deliver siRNA stably within cells is still unavailable. Therefore, in this study we synthesized a library of both non-targeted (proteinsiRNA) nanoparticles (NPs) and targeted (antibody conjugated protein-siRNA) NPs and evaluated ability to stably deliver siR
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Venkataraman, Srividhya, Mehdi Shahgolzari, Afagh Yavari, and Kathleen Hefferon. "Bacteriophages as Targeted Therapeutic Vehicles: Challenges and Opportunities." Bioengineering 12, no. 5 (2025): 469. https://doi.org/10.3390/bioengineering12050469.

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Bacteriophages, with their distinctive ability to selectively target host bacteria, stand out as a compelling tool in the realm of drug and gene delivery. Their assembly from proteins and nucleic acids, coupled with their modifiable and biologically unique properties, enables them to serve as efficient and safe delivery systems. Unlike conventional nanocarriers, which face limitations such as non-specific targeting, cytotoxicity, and reduced transfection efficiency in vivo, engineered phages exhibit promising potential to overcome these hurdles and improve delivery outcomes. This review highli
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Koev, Todor T., Hannah C. Harris, Sara Kiamehr, Yaroslav Z. Khimyak, and Frederick J. Warren. "Starch hydrogels as targeted colonic drug delivery vehicles." Carbohydrate Polymers 289 (August 2022): 119413. http://dx.doi.org/10.1016/j.carbpol.2022.119413.

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Ali, Yousaf, Ali Alqudah, Sadiq Ahmad, Shafida Abd Hamid, and Umar Farooq. "Macromolecules as targeted drugs delivery vehicles: an overview." Designed Monomers and Polymers 22, no. 1 (2019): 91–97. http://dx.doi.org/10.1080/15685551.2019.1591681.

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Wu, Guicun, Fang Zhou, Linfu Ge, Ximin Liu, and Fansheng Kong. "Novel Mannan-PEG-PE Modified Bioadhesive PLGA Nanoparticles for Targeted Gene Delivery." Journal of Nanomaterials 2012 (2012): 1–9. http://dx.doi.org/10.1155/2012/981670.

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Purpose. Biodegradable polymeric nanoparticles have been used frequently as gene delivery vehicles. The aim of this study is to modify bioadhesive PLGA nanoparticles with novel synthetic mannan-PEG-PE (MN-PEG-PE) to obtain active targeted gene delivery system.Methods. Mannan-PEG-PE ligands were synthesized and modified onto the NPs/pEGFP complexes. The modification rate was optimized, and the characteristics of the vehicle were evaluated. Then, the modified vectors were intravenous delivered to rats, andin vivotargeting behavior of MN-PEG-PE modified PLGA nanoparticles/pEGFP complexes (MN-PEG-
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Zhogla, V., E. Bletsko, S. Gayibova, V. Shmanai, and S. Shcharbina. "Targeted drug delivery based on multifunctional dendrimer nanosystems." Science and Innovations 1, no. 5 (2025): 78–83. https://doi.org/10.29235/1818-9857-2025-5-78-83.

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Targeted delivery of drugs based on dendrimers has a number of advantages for the treatment of cancer. The drug is delivered to specific tissues and organs, thereby minimizing the undesirable effect on healthy cells. Nanoparticles not only reduce the toxicity of anticancer drugs, but also increase their bioavailability and stability in the body. Dendrimers are considered the most promising as drug delivery vehicles due to their non-immunogenicity and controlled synthesis. They have shown their effectiveness in many areas of biology and medicine, namely chemotherapy, vaccine development, and de
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Dissertations / Theses on the topic "Targeted Delivery Vehicles"

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Morton, Stephen Winford. "Engineering translational multi-therapeutic targeted delivery vehicles for disease management." Thesis, Massachusetts Institute of Technology, 2015. http://hdl.handle.net/1721.1/98798.

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Thesis: Sc. D., Massachusetts Institute of Technology, Department of Chemical Engineering, June 2015.<br>Cataloged from PDF version of thesis. "May 21, 2015."<br>Includes bibliographical references.<br>The complexity of growth, survival, and death signaling pathways in cancer continues to motivate extensive investigations using systems biology approaches to better inform treatments. Many of these drugs and drug combinations, however, are highly toxic, due to lack of targeting and poor pharmacokinetics, and are not easily delivered together due to solubility issues - requiring high levels of pa
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Sakhalkar, Harshad S. "Enhanced Adhension of Biodegradable Drug Delivery Vehicles to Inflamed Endothelium." Ohio University / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1129916752.

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Urnauer, Sarah [Verfasser], and Ernst [Akademischer Betreuer] Wagner. "Improved synthetic gene delivery vehicles for advanced bioimaging-guided tumor-targeted application of the sodium iodide symporter (NIS) as theranostic gene / Sarah Urnauer ; Betreuer: Ernst Wagner." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2017. http://d-nb.info/1148941177/34.

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Wattanakaroon, Wanida. "Development of an interleukin 2 receptor targeted gene therapy vehicle." Texas A&M University, 2005. http://hdl.handle.net/1969.1/3724.

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The effectiveness of most chemotherapeutic regimens is limited by the toxicity of the therapy to normal healthy cells. Therapies to selectively modulate abnormal T cells bearing the interleukin 2 receptor (IL-2R) have been developed to treat diseases associated with aberrant immune response. This study describes the development and optimization of a targeted gene or oligonucleotide therapy vehicle to IL-2R bearing T cells for selective elimination of these cells. In this work, a monoclonal antibody to the IL-2R was used to target the oligonucleotide delivery vehicle which consisted of a polyam
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Sodha, Anirudhasingh. "DEVELOPMENT AND COMMERCIALIZATION OF HEPATOCYTE TARGETED DRUG DELIVERY VEHICLE FOR PHARMACEUTICAL APPLICATION." Case Western Reserve University School of Graduate Studies / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=case1247192896.

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Halley, Patrick D. "DNA Origami as a Drug Delivery Vehicle for in vitro and in vivo Applications." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1480632777328142.

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Ramos, Nuno José Prego. "Crosslinked Hyaluronic Acid nanoparticles as delivery vehicles for dendritic cell-targeted vaccines." Master's thesis, 2016. http://hdl.handle.net/10362/17792.

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RESUMO: O sistema imunitário tem sido o alvo dos mais recentes avanços no tratamento do cancro. Imunoconjugados, terapias direcionadas e imunoterapias são as classes de medicamentos mais investigados no tratamento do cancro, com muitos candidatos a fármacos atualmente em fase de desenvolvimento pré-clínico e fase final de desenvolvimento clínico. Terapias focadas em células dendríticas (CDs) são muito promissoras, uma vez que as CDs são células apresentadoras de antigénios, o que as transforma em alvos interessantes para controlar a resposta imune aquando da presença de células cancerígenas.
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Mitra, Raja. "Targeted Delivery of Cytotoxic Metal Complexes into Cancer Cells with and without Macromolecular Vehicles." Thesis, 2013. http://etd.iisc.ac.in/handle/2005/3392.

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Anticancer active metal complexes such as cisplatin are routinely used for treating various cancers since 1978. However, the side effects of cisplatin overwhelm its therapeutic potential, especially in the latter stages of treatment. The nonspecific cytotoxicity of drugs could be avoided if targeted delivery to cancer cells is achieved using two different methodologies namely, enhanced permeability and retention in solid tumors (EPR) and receptor mediated endocytosis using a homing agent (RME). Ru(II)-arene complexes which are delivered specifically into cancer cells by the transferrin enzyme
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Mitra, Raja. "Targeted Delivery of Cytotoxic Metal Complexes into Cancer Cells with and without Macromolecular Vehicles." Thesis, 2013. http://etd.iisc.ernet.in/2005/3392.

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Anticancer active metal complexes such as cisplatin are routinely used for treating various cancers since 1978. However, the side effects of cisplatin overwhelm its therapeutic potential, especially in the latter stages of treatment. The nonspecific cytotoxicity of drugs could be avoided if targeted delivery to cancer cells is achieved using two different methodologies namely, enhanced permeability and retention in solid tumors (EPR) and receptor mediated endocytosis using a homing agent (RME). Ru(II)-arene complexes which are delivered specifically into cancer cells by the transferrin enzyme
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Han, Han. "Development of Targeted, Polymeric Delivery Vehicles for Camptothesin and siRNA Via Boronic Acid-Diol Complexation." Thesis, 2013. https://thesis.library.caltech.edu/7443/1/Han%20Thesis.pdf.

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<p>Our research lab has developed polymer-based nanoparticle delivery systems for the anticancer drug, camptothecin (CPT), CRLX101; and for the small interfering RNA (siRNA), CALAA-01. CRLX101 has shown great success in both animal studies and clinical trials. However, it is incapable of achieving targeted delivery. CALAA-01 has demonstrated effectiveness in a phase I clinical trial. However, it suffers from its rapid in vivo clearance. To address the issues of targeting in the anticancer drug delivery system and the short circulation time in the siRNA delivery system, we have created a new de
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Books on the topic "Targeted Delivery Vehicles"

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Claudio, Nastruzzi, ed. Lipospheres in drug targets and delivery: Approaches, methods, and applications. CRC Press, 2005.

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Lim, Rebecca, Jessica E. Frith, Gina D. Kusuma, and Christopher G. Sobey, eds. Stem Cells as Targeted Drug Delivery Vehicles. Frontiers Media SA, 2021. http://dx.doi.org/10.3389/978-2-88966-448-1.

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Nastruzzi, Claudio. Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications. Taylor & Francis Group, 2004.

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Nastruzzi, Claudio. Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications. Taylor & Francis Group, 2004.

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Nastruzzi, Claudio. Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications. Taylor & Francis Group, 2004.

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Nastruzzi, Claudio. Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications. Taylor & Francis Group, 2004.

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Nastruzzi, Claudio. Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications. Taylor & Francis Group, 2005.

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Esplin, Emron, and Margarida Vale de Gato, eds. Translated Poe. The Rowman & Littlefield Publishing Group, Inc., 2014. https://doi.org/10.5040/9781611464153.

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Few, if any, U.S. writers are as important to the history of world literature as Edgar Allan Poe, and few, if any, U.S. authors owe so much of their current reputations to the process of translation. Translated Poe brings together 31 essays from 19 different national/literary traditions to demonstrate Poe’s extensive influence on world literature and thought while revealing the importance of the vehicle that delivers Poe to the world—translation. Translated Poe is not preoccupied with judging the “quality” of any given Poe translation nor with assessing what a specific translation of Poe must
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Book chapters on the topic "Targeted Delivery Vehicles"

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Joshi, Ramakant, Rajendra Chauhan, Wasim Akram, Pawan Kushwah, Hemant Mourya, and Navneet Garud. "Vehicles for Delivery of Therapeutic Agent for Cancer Therapy." In Targeted Cancer Therapy in Biomedical Engineering. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-9786-0_21.

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Yadav, Khushwant S., Rajiv Saxena, and Govind Soni. "Chapter 9. Nanogels as Targeted Drug Delivery Vehicles." In Nanogels for Biomedical Applications. Royal Society of Chemistry, 2017. http://dx.doi.org/10.1039/9781788010481-00143.

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Gulati, Pooja, Anubhuti Kawatra, Sonika Dhillon, and Rakhi Dhankhar. "Bacterial Drug Delivery Vehicles for Targeted Treatment of Tumors." In Microbial Products. CRC Press, 2022. http://dx.doi.org/10.1201/9781003306931-25.

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Matlou, Gauta Gold, and Heidi Abrahamse. "Metallic Core-Shell Nanoparticles as Drug Delivery Vehicles in Targeted Photodynamic Therapy of Cancer." In Handbook of Oxidative Stress in Cancer: Therapeutic Aspects. Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-5422-0_208.

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Matlou, Gauta Gold, and Heidi Abrahamse. "Metallic Core-Shell Nanoparticles as Drug Delivery Vehicles in Targeted Photodynamic Therapy of Cancer." In Handbook of Oxidative Stress in Cancer: Therapeutic Aspects. Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-1247-3_208-1.

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Dolly, J. O., V. B. O’Leary, G. W. Lawrence, and S. V. Ovsepian. "Pharmacology of Botulinum Neurotoxins: Exploitation of Their Multifunctional Activities as Transmitter Release Inhibitors and Neuron-Targeted Delivery Vehicles." In Molecular Aspects of Botulinum Neurotoxin. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-9454-6_2.

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Hall, B., M. Andreeff, and F. Marini. "The Participation of Mesenchymal Stem Cells in Tumor Stroma Formation and Their Application as Targeted-Gene Delivery Vehicles." In Handbook of Experimental Pharmacology. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-68976-8_12.

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Höfer, Andreas, Erhard Esl, Daniel Türk, and Veronika Hüttinger. "Conception and Development of a Last Mile Vehicle for Urban Areas." In Small Electric Vehicles. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-65843-4_13.

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AbstractIn megacities, increasing globalization effects are leading to rapidly increasing prosperity and augmented purchasing power, and thus to a growing need for punctual, cost-effective, and environmentally friendly delivery of goods. A smart, small electric vehicle concept is presented that targets on meeting the requirements for the delivery of goods in urban areas and that is designed especially for the delivery on the last mile. This last mile vehicle (LMV) for cargo transportation is attached to a truck. Whenever it is needed, for example to deliver goods into narrow streets, in pedest
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Milenic, Diane E. "Antibody Engineering: Optimizing the Delivery Vehicle." In Monoclonal Antibody and Peptide-Targeted Radiotherapy of Cancer. John Wiley & Sons, Inc., 2010. http://dx.doi.org/10.1002/9780470613214.ch1.

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Sharma, Manu, Tapasvi Gupta, Namita Gupta, et al. "Targeted Therapy for Neurological Disorders Using Nanomaterial-Based Drug Delivery Vehicle." In Nanomaterials for Drug Delivery and Neurological Diseases Management. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-0308-1_7.

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Conference papers on the topic "Targeted Delivery Vehicles"

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King, Xi, Elijah Nazarzadeh, Manlio Tassieri, Julien Reboud, and Jonathan M. Cooper. "Ultrasonic Surface Acoustic Wave platform for targeted pulmonary delivery of nano drug vehicles." In 2019 IEEE International Ultrasonics Symposium (IUS). IEEE, 2019. http://dx.doi.org/10.1109/ultsym.2019.8925726.

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David, L. L., and M. Singh. "The Efficacy of a Transferrin Targeted Dual Loaded Anticancer Drug Delivery System Using Functionalized Gold Nanoparticles as Delivery Vehicles." In The 4th World Congress on Recent Advances in Nanotechnology. Avestia Publishing, 2019. http://dx.doi.org/10.11159/nddte19.105.

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Mullin, Lee, Ping Ma, Saurabh Wadhwa, Lei Peng, Russell J. Mumper, and Paul A. Dayton. "Design and testing of acoustically-active therapeutic nanocapsule delivery vehicles for ultrasound-targeted chemotherapy." In 2010 IEEE Ultrasonics Symposium (IUS). IEEE, 2010. http://dx.doi.org/10.1109/ultsym.2010.5935733.

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Lammert, Michael P., Kevin Walkowicz, Adam Duran, and Petr Sindler. "Measured Laboratory and In-Use Fuel Economy Observed over Targeted Drive Cycles for Comparable Hybrid and Conventional Package Delivery Vehicles." In SAE 2012 Commercial Vehicle Engineering Congress. SAE International, 2012. http://dx.doi.org/10.4271/2012-01-2049.

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Tartis, Michaelann S., Jan Marik, Azadeh Kheirolomoom, et al. "Pharmacokinetics of Encapsulated Paclitaxel: Multi-Probe Analysis With PET." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176435.

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We have combined two imaging probes and used PET as a means to provide image-based validation for a novel targeted drug delivery system. The first probe was a direct labeling of the drug [18F]fluoropaclitaxel [1–3], which was inserted into various carrier vehicle formulations. The second probe, [18F]fluoro-1,2-dipalmitoyl-sn-glycerol, i.e. [18F]FDP involved radiolabeling the lipid vehicle. Paclitaxel, which is poorly soluble in aqueous media, also has limited solubility and stability in lipophilic environments such as liposomes. Stable association of paclitaxel with the lipid bilayer is affect
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Alan Tshinkobo, Matanda, John Ikome, and Ibrahim Idowu. "Enhancing E-commerce Efficiency: AI Solutions for Last-Mile Delivery in Johannesburg." In 16th International Conference on Applied Human Factors and Ergonomics (AHFE 2025). AHFE International, 2025. https://doi.org/10.54941/ahfe1006451.

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In the South African context, Johannesburg has become the hub of economic activities and the case of e-commerce expansion comes with a problem of last mile delivery. The challenges caused by the void in artificial intelligence (AI) literature are well known, but such application in Johannesburg’s logistical environment where there is a high level of traffic, poor infrastructure and even laws is lacking.This study seeks to bridge that gap by employing a quantitative approach, drawing on statistical data from a variety of sources, including academic journals, industry reports, and case studies o
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Jurney, Patrick, Rachit Agarwal, Vikramjit Singh, Krishnendu Roy, S. V. Sreenivasan, and Li Shi. "The Effect of Nanoparticle Size on Margination and Adhesion Propensity in Artificial Micro-Capillaries." In ASME 2012 Third International Conference on Micro/Nanoscale Heat and Mass Transfer. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/mnhmt2012-75258.

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Intravenous injection of nanoparticles as drug delivery vehicles is a common practice used in in-vivo and clinical trials of therapeutic agents to target specific cancerous or pathogenic sites. The vascular flow dynamics of nanocarriers in human capillaries play an important role in the ultimate efficacy of this drug delivery method. This article reports an experimental study of the effect of nanoparticle size on their margination and adhesion propensity in micro fabricated microfluidic channels of a half elliptical cross-section. Spherical polystyrene particles ranging in diameter from 60 to
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Satme, Joud N., Ryan Yount, Nikita Goujevskii, Luke Jannazzo, and Austin R. J. Downey. "Sensor Package Deployment and Recovery Cone With Integrated Video Streaming for Rapid Structural Health Monitoring." In ASME 2024 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2024. http://dx.doi.org/10.1115/smasis2024-140435.

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Abstract This study presents an approach for structural health monitoring (SHM) of remote and hazardous structures using unpiloted aerial vehicles (UAVs). The method focuses on overcoming the challenges associated with traditional sensor deployment techniques, which are often costly and risky due to the decaying nature of the targeted structures. Utilizing a multi-rotor UAV platform, a streaming camera is integrated into a recovery cone to aid in visual alignment during deployment and retrieval providing a safe and cost-effective means of sensor delivery. The paper covers the design of a video
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Aslam, Iqra, Adina Aniculaesei, Abhishek Buragohain, Meng Zhang, Daniel Bamal, and Andreas Rausch. "Runtime Safety Assurance of Autonomous Last-Mile Delivery Vehicles in Urban-like Environment." In 2024 Stuttgart International Symposium. SAE International, 2024. http://dx.doi.org/10.4271/2024-01-2991.

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&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;The conventional process of last-mile delivery logistics often leads to safety problems for road users and a high level of environmental pollution. Delivery drivers must deal with frequent stops, search for a convenient parking spot and sometimes navigate through the narrow streets causing traffic congestion and possibly safety issues for the ego vehicle as well as for other traffic participants. This process is not only time consuming but also environmentally impactful, especially in low-emission zones where prolonged v
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Kukkillaya U, Saketh, Muralidhar Gumma, Srinivasarao Potarlanka, and Padmaja Durgam. "A Multi-Disciplinary Optimization Approach for Lightweighting and Performance Improvement of Electric Light Commercial Vehicle." In Symposium on International Automotive Technology. SAE International, 2024. http://dx.doi.org/10.4271/2024-26-0252.

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&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;Rapid Urbanisation, in recent times, has created an exponential demand for light commercial vehicles. Electric vehicles are seen as a way to reduce the impact of emissions due to transportation in urban areas. Due to the growth of e-commerce, commercial transportation, and particularly last-mile delivery, is anticipated to increase. In this context, electric light commercial vehicles (eLCVs) have the potential to be a promising solution by tackling the emission impacts, ensuring faster delivery along with ideal running c
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Reports on the topic "Targeted Delivery Vehicles"

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Chen, Xiaoyuan. Mesenchymal Stem Cell as Targeted-Delivery Vehicle in Breast Cancer. Defense Technical Information Center, 2008. http://dx.doi.org/10.21236/ada487022.

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Cheng, Zhen. Mesenchymal Stem Cell as Targeted-Delivery Vehicle in Breast Cancer. Defense Technical Information Center, 2010. http://dx.doi.org/10.21236/ada538054.

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Coyner, Kelley, and Jason Bittner. Automated Vehicles and Infrastructure Enablers: Logistics and Delivery. SAE International, 2023. http://dx.doi.org/10.4271/epr2023021.

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&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;Like the shift from horse drawn carriages to cars, the emergence of delivery robots marks a shift from driverless vehicles to automated logistics vehicles where form follows function. On paper, the business cases are compelling and the use cases seemingly unbounded. Vehicles may be conventional in the form of trucks and industrial equipment of all types, or as purpose-built vehicles on with widely varying cargo capacities. Proof of concepts and pilots are moving forward on roadways, sidewalks, and doorsteps, as well as i
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Abdul Hamid, Umar Zakir. Product Governance and Management for Software-defined Battery Electric Vehicles. SAE International, 2024. http://dx.doi.org/10.4271/epr2024025.

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&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;In recent years, battery electric vehicles (BEVs) have experienced significant sales growth, marked by advancements in features and market delivery. This evolution intersects with innovative software-defined vehicles, which have transformed automotive supply chains, introducing new BEV brands from both emerging and mature markets. The critical role of software in software-defined battery electric vehicles (SD-BEVs) is pivotal for enhancing user experience and ensuring adherence to rigorous safety, performance, and qualit
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Qian, Yuping, Yangjun Zhang, and WEILIN ZHUGE. Key Technology Challenges of Electric Ducted Fan Propulsion Systems for eVTOL. SAE International, 2023. http://dx.doi.org/10.4271/epr2023027.

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&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;Electrical vertical takeoff and landing (eVTOL) vehicles for urban air mobility (UAM) are garnering increased attention from both the automotive and aerospace industries, with use cases ranging from individual transportation, public service, cargo delivery, and more. Distributed electric propulsion systems are their main technical feature; they determine vehicle size and propulsion efficiency and provide distributed thrust to achieve attitude control. Considering the intended role of eVTOL vehicles, ducted-fan systems ar
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Muelaner, Jody E. The Role of Hybrid Vehicles in a Net-zero Transport System. SAE International, 2024. http://dx.doi.org/10.4271/epr2024021.

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&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;As the world looks to net-zero emissions goals, hybrid electric vehicles may play an increasingly important role. For passenger electric vehicles (EVs) that predominantly make short journeys but occasionally need to make longer trips, electrofuel range extension may be more cost effective than either hydrogen or rapid charging. Micro gas turbines and catalytic combustion show significant potential to deliver low-cost, low-maintenance, lightweight engines with virtually no emissions, and hydrocarbon consuming solid oxide
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Chalmers, Seth. The Challenges of Next-gen ADAS and ADS and Related Vehicle Safety Topics. SAE International, 2025. https://doi.org/10.4271/epr2025003.

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&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;Advanced driver assistance systems (ADAS) and automated driving systems (ADS) continue to expand into the market at a rapid pace. As improved (i.e., next generation) versions of these systems become available, they will continue to face many challenges in their implementation and benefits for safety and driving operations. The solution will involve many parties, including road safety professionals and researchers who see the potential in these systems but may have difficulties keeping up with them, and safety advocates w
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Noone, Emily, and Lydia Harriss. Hypersonic missiles. Parliamentary Office of Science and Technology, 2023. http://dx.doi.org/10.58248/pn696.

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This POSTnote looks at hypersonic missile technologies, efforts to develop them, potential applications, and the possible challenges they may present for missile defence and global stability. Key Points: • Hypersonic missiles combine speeds of over five times the speed of sound with significant manoeuvrability during flight. • Their manoeuvrability enables them to change trajectory during flight, making their flight-path and target difficult to predict. • They fly at lower altitudes than ballistic missiles, which means that they may be harder to track at long distances with some surface-based
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