Relevant bibliographies by topics / Targetted liposome

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Targetted liposome'

Author: Grafiati
Published: 4 June 2021
Last updated: 3 February 2022

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Journal articles on the topic "Targetted liposome"

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Sivathanu, Dr S. Bhagavathy, Shivapriya G, and Shivapriya G. "Formulation, Characterization and In vitro Drug Delivery of Vitexin Loaded Liposomes." International Journal of Pharmaceutical Sciences and Nanotechnology 14, no. 2 (2021): 5364–71. http://dx.doi.org/10.37285/ijpsn.2021.14.2.2.

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Liposome is a spherical vesicle which contains atleast one lipid bilayer. Liposomes are used as a novel drug carriers because of its hydrophobic and hydrophilic nature, it has many advantages in the field of medical sciences. There are some other drug carriers like dendrimers, micelles, niosomes. Out of all, liposomes are considered to be the most promising agent for drug delivery. The uniqueness of liposome is when it is used as a pharmaceutical drug, it acts as a natural receptor. Thus it acts as an antigen and binds with the antibody (cancer cell) without causing any damage to the adjacent
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Cattel, Luigi, Maurizio Ceruti, and Franco Dosio. "From Conventional to Stealth Liposomes a new Frontier in Cancer Chemotherapy." Tumori Journal 89, no. 3 (2003): 237–49. http://dx.doi.org/10.1177/030089160308900302.

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Many attempts have been made to achieve good selectivity to targeted tumor cells by preparing specialized carrier agents that are therapeutically profitable for anticancer therapy. Among these, liposomes are the most studied colloidal particles thus far applied in medicine and in particular in antitumor therapy. Although they were first described in the 1960s, only at the beginning of 1990s did the first therapeutic liposomes appear on the market. The first-generation liposomes (conventional liposomes) comprised a liposome-containing amphotericin B, Ambisome (Nexstar, Boulder, CO, USA), used a
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Gorbik, V. S., Z. S. Shprakh, Z. M. Kozlova, and V. G. Salova. "LIPOSOMES AS A TARGETED DELIVERY SYSTEM OF DRUGS (REVIEW)." Russian Journal of Biotherapy 20, no. 1 (2021): 33–41. http://dx.doi.org/10.17650/1726-9784-2021-20-1-33-41.

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Liposomal targeted drug delivery makes it possible to achieve effective concentration in the target cell under various pathological conditions. The main advantage of liposomal particles is their biodegradability and immunological neutrality, which improves the safety profile of drugs. The review provides information on the composition of liposomes: the main component of the liposomal membrane is phospholipids, which provide its strength and protect from mechanical impacts. Liposomal particles are distinguished by the size and number of bilayer membranes, also secreted liposomes with a non‑lame
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Medina, Oula Peñate, Tuula Peñate Medina, Jana Humbert, et al. "Using Alendronic Acid Coupled Fluorescently Labelled SM Liposomes as a Vehicle for Bone Targeting." Current Pharmaceutical Design 26, no. 46 (2020): 6021–27. http://dx.doi.org/10.2174/1381612826666200614175905.

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Background: We recently developed a liposomal nanoparticle system that can be used for drug delivery and simultaneously be monitored by optical or photoacoustic imaging devices. Here we tested the efficacy of alendronate as a homing molecule in SM-liposomes for bone targeting. Methods: Alendronate was immobilized covalently on the liposomal surface and the fluorescent dye indocyanine green was used as a payload in the liposomes. The indocyanine green delivery was analyzed by 3D optical tomography, optical fluorescence scanner, photoacoustic imaging, and by ex-vivo biodistribution studies. Resu
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Tansi, Felista L., Ronny Rüger, Ansgar M. Kollmeier, et al. "Targeting the Tumor Microenvironment with Fluorescence-Activatable Bispecific Endoglin/Fibroblast Activation Protein Targeting Liposomes." Pharmaceutics 12, no. 4 (2020): 370. http://dx.doi.org/10.3390/pharmaceutics12040370.

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Liposomes are biocompatible nanocarriers with promising features for targeted delivery of contrast agents and drugs into the tumor microenvironment, for imaging and therapy purposes. Liposome-based simultaneous targeting of tumor associated fibroblast and the vasculature is promising, but the heterogeneity of tumors entails a thorough validation of suitable markers for targeted delivery. Thus, we elucidated the potential of bispecific liposomes targeting the fibroblast activation protein (FAP) on tumor stromal fibroblasts, together with endoglin which is overexpressed on tumor neovascular cell
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Peñate-Medina, Tuula, Christabel Damoah, Miriam Benezra, et al. "Alpha-MSH Targeted Liposomal Nanoparticle for Imaging in Inflammatory Bowel Disease (IBD)." Current Pharmaceutical Design 26, no. 31 (2020): 3840–46. http://dx.doi.org/10.2174/1381612826666200727002716.

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Background: The purpose of our study was to find a novel targeted imaging and drug delivery vehicle for inflammatory bowel disease (IBD). IBD is a common and troublesome disease that still lacks effective therapy and imaging options. As an attempt to improve the disease treatment, we tested αMSH for the targeting of nanoliposomes to IBD sites. αMSH, an endogenous tridecapeptide, binds to the melanocortin-1 receptor (MC1-R) and has anti-inflammatory and immunomodulating effects. MC1-R is found on macrophages, neutrophils and the renal tubule system. We formulated and tested a liposomal nanopart
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Nijen Twilhaar, Maarten K., Lucas Czentner, Joanna Grabowska, et al. "Optimization of Liposomes for Antigen Targeting to Splenic CD169+ Macrophages." Pharmaceutics 12, no. 12 (2020): 1138. http://dx.doi.org/10.3390/pharmaceutics12121138.

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Despite promising progress in cancer vaccination, therapeutic effectiveness is often insufficient. Cancer vaccine effectiveness could be enhanced by targeting vaccine antigens to antigen-presenting cells, thereby increasing T-cell activation. CD169-expressing splenic macrophages efficiently capture particulate antigens from the blood and transfer these antigens to dendritic cells for the activation of CD8+ T cells. In this study, we incorporated a physiological ligand for CD169, the ganglioside GM3, into liposomes to enhance liposome uptake by CD169+ macrophages. We assessed how variation in t
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Naik, Himgauri, Jafrin Jobayer Sonju, Sitanshu Singh, et al. "Lipidated Peptidomimetic Ligand-Functionalized HER2 Targeted Liposome as Nano-Carrier Designed for Doxorubicin Delivery in Cancer Therapy." Pharmaceuticals 14, no. 3 (2021): 221. http://dx.doi.org/10.3390/ph14030221.

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The therapeutic index of chemotherapeutic agents can be improved by the use of nano-carrier-mediated chemotherapeutic delivery. Ligand-targeted drug delivery can be used to achieve selective and specific delivery of chemotherapeutic agents to cancer cells. In this study, we prepared a peptidomimetic conjugate (SA-5)-tagged doxorubicin (Dox) incorporated liposome (LP) formulation (SA-5-Dox-LP) to evaluate the targeted delivery potential of SA-5 in human epidermal growth factor receptor-2 (HER2) overexpressed non-small-cell lung cancer (NSCLC) and breast cancer cell lines. The liposome was prepa
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Harokopakis, Evlambia, George Hajishengallis, and Suzanne M. Michalek. "Effectiveness of Liposomes Possessing Surface-Linked Recombinant B Subunit of Cholera Toxin as an Oral Antigen Delivery System." Infection and Immunity 66, no. 9 (1998): 4299–304. http://dx.doi.org/10.1128/iai.66.9.4299-4304.1998.

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ABSTRACT Liposomes appear to be a promising oral antigen delivery system for the development of vaccines against infectious diseases, although their uptake efficiency by Peyer’s patches in the gut and the subsequent induction of mucosal immunoglobulin A (IgA) responses remain a major concern. Aiming at targeted delivery of liposomal immunogens, we have previously reported the conjugation via a thioether bond of the GM1 ganglioside-binding subunit of cholera toxin (CTB) to the liposomal outer surface. In the present study, we have investigated the effectiveness of liposomes containing the saliv
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Nosova, A. S., O. O. Koloskova, I. P. Shilovskiy, Yu L. Sebyakin, and M. R. Khaitov. "Lactose-based glycoconjugates with variable spacers for design of liver-targeted liposomes." Biomeditsinskaya Khimiya 63, no. 5 (2017): 467–71. http://dx.doi.org/10.18097/pbmc20176305467.

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Asialoglycoprotein receptors are highly abundant on the hepatocyte surface and have specific binding sites for blood serum glycoproteins. Such discovery resulted in development of liver-targeted drug delivery systems because modification of the liposomal surface by carbohydrate derivatives results in an increase of endocytosis, which facilitates selective uptake of such systems by hepatocytes. In this study we have synthesized novel lactose derivatives containing a palmitic hydrophobic domain. They were used for modification of the liposome surface. Transfection activity of modified liposomes
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Dissertations / Theses on the topic "Targetted liposome"

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Baki, Mert. "Bone Marrow Targeted Liposomal Drug Delivery Systems." Master's thesis, METU, 2011. http://etd.lib.metu.edu.tr/upload/12613251/index.pdf.

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Homing is the process that stem cells move to their own stem cell niches under the influence of chemokines like stromal-derived factor-1&alpha<br>(SDF-1&alpha<br>) upon bone marrow transplantation (BMT). There is a need for increasing homing efficiency after BMT since only 10-15% of the transplanted cells can home to their own niches and a limited amount of donor marrow can be transplanted. In this study, we aimed to develop and characterize bone marrow targeted liposomal SDF-1&alpha<br>delivery system prepared by extrusion method. Alendronate conjugation was chosen to target the liposomes to
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Loughrey, Helen. "Targeted liposomes." Thesis, University of British Columbia, 1989. http://hdl.handle.net/2429/29180.

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This thesis presents an optimized and general procedure for coupling proteins to liposomes and investigates certain aspects of the interaction of liposomes with components of the circulation. The object of these studies was to develop straightforward methods for the preparation of well characterized protein-liposome conjugates which exhibit extended circulation half-lives in the blood. These favorable properties should potentiate the use of protein coupled vesicles in in vivo applications such as targeting or diagnostic protocols. A general approach for the preparation of protein-liposome conj
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Harasym, Troy O. "Antibody-targeted liposomal systems." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq25066.pdf.

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Bowen, Tian. "Liposome-QD hybrids and the development of targeted theranostic modalities." Thesis, University of London, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.535499.

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Javadi, Marjan. "Novel Liposomes for Targeted Delivery of Drugs and Plasmids." BYU ScholarsArchive, 2013. https://scholarsarchive.byu.edu/etd/3879.

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People receiving chemotherapy not only suffer from side effects of therapeutics but also must buy expensive drugs. Targeted drug and gene delivery directed to specific tumor-cells is one way to reduce the side effect of drugs and use less amount of therapeutics. In this research, two novel liposomal nanocarriers were developed. This nanocarrier, called an eLiposome, is basically one or more emulsion droplets inside a liposome. Emulsion droplets are made of perfluorocarbons which usually have a high vapor pressure. Calcein (as a model drug) and Paclitaxel were used to demonstrate drug delivery,
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Harrington, Kevin Joseph. "Pegylated Liposome-targeted Radiosensitisers for the Treatment of Head and neck Cancer." Thesis, Imperial College London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.506160.

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Divi, Murali Krishna. "Development and evaluation of brain tumor targeted liposome delivery system for paclitaxel." View the abstract Download the full-text PDF version, 2008. http://etd.utmem.edu/ABSTRACTS/2007-012-Divi-index.html.

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Thesis (Ph.D.)--University of Tennessee Health Science Center, 2008.<br>Title from title page screen (viewed on January 6, 2009). Research advisor: George C Wood, Ph.D. Document formatted into pages (xii, 126 p. : ill.). Vita. Abstract. Includes bibliographical references (p. 112-126).
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Stevens, Phillip James. "An approach to drug formulation and targeting liposomes and lipid nanoparticles for folate receptor targeting." Connect to this title online, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1111092653.

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Thesis (Ph. D.)--Ohio State University, 2005.<br>Title from first page of PDF file. Document formatted into pages; contains xvi, 110 p.; also includes graphics (some col.) Includes bibliographical references (p. 98-110). Available online via OhioLINK's ETD Center
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Hartley, Jonathan Michael. "Surface Modification of Liposomes Containing Nanoemulsions." BYU ScholarsArchive, 2011. https://scholarsarchive.byu.edu/etd/2846.

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Many attempts have been made to make cancer therapy more selective and less detrimental to the health of the patients. Nanoparticles have emerged as a way to solve some of the problems of traditional chemotherapy. Nanoparticles can provide protection for the therapeutic from degradation or clearance, as well as protection to healthy tissue from the damaging effects of chemotherapy drugs. Researchers are pursuing different strategies but all have the same goals of improving the outcomes of cancer patients. The field of controlled release of drugs has increased significantly in hopes of better t
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Jayanna, Prashanth K. Petrenko Valery. "Therapeutic liposomes for prostate cancer targeted by phage fusion coat proteins." Auburn, Ala., 2009. http://hdl.handle.net/10415/1994.

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Books on the topic "Targetted liposome"

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1960-, Tyle Praveen, and Ram Bhanu P. 1951-, eds. Targeted therapeutic systems. Dekker, 1990.

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Bicanic, Tihana, and Thomas S. Harrison. Fungal central nervous system infections. Edited by Christopher C. Kibbler, Richard Barton, Neil A. R. Gow, Susan Howell, Donna M. MacCallum, and Rohini J. Manuel. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198755388.003.0022.

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Infections of the central nervous system (CNS) are amongst the most severe of all fungal infections. Cryptococcus neoformans is the commonest cause of adult meningitis in many countries with high HIV prevalence. C gattii is usually seen in the tropics in apparently immunocompetent patients. Meningitis is also caused by Candida in premature babies, and by the dimorphic fungi in endemic areas. CNS infections with Aspergillus, the mucormycetes, and less common moulds usually present as intracranial mass lesions in immunocompromised hosts. Early suspicion, prompt imaging, and appropriate samples f
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Book chapters on the topic "Targetted liposome"

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Vyas, Suresh Prasad, Amit K. Goyal, and Kapil Khatri. "Mannosylated Liposomes for Targeted Vaccines Delivery." In Methods in Molecular Biology. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-360-2_12.

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Pradhan, Pallab, Rinti Banerjee, Dhirendra Bahadur, Christian Koch, Olga Mykhaylyk, and Christian Plank. "Targeted Magnetic Liposomes Loaded with Doxorubicin." In Methods in Molecular Biology. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-360-2_19.

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Pradhan, Pallab, Rinti Banerjee, Dhirendra Bahadur, Christian Koch, Olga Mykhaylyk, and Christian Plank. "Targeted Magnetic Liposomes Loaded with Doxorubicin." In Methods in Molecular Biology. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-6591-5_21.

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Lai, Francesco, Michele Schlich, Chiara Sinico, and Anna Maria Fadda. "Liposomes as Brain Targeted Delivery Systems." In Neuromethods. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0838-8_2.

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He, W. "Chapter 20. Liposomes in Targeted Drug Delivery." In Soft Matter Series. Royal Society of Chemistry, 2021. http://dx.doi.org/10.1039/9781839161124-00499.

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Scherphof, G. L. "In Vivo Behavior of Liposomes: Interactions with the Mononuclear Phagocyte System and Implications for Drug Targeting." In Targeted Drug Delivery. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-75862-1_8.

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Milani, Doniya, Umi Athiyah, Dewi Melani Hariyadi, and Yashwant V. Pathak. "Surface Modifications of Liposomes for Drug Targeting." In Surface Modification of Nanoparticles for Targeted Drug Delivery. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-06115-9_11.

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Gabizon, Alberto, Hilary Shmeeda, Hemda Baabur-Cohen, and Ronit Satchi-Fainaro. "Liposomes and Polymers in Folate-Targeted Cancer Therapeutics." In Targeted Drug Strategies for Cancer and Inflammation. Springer US, 2011. http://dx.doi.org/10.1007/978-1-4419-8417-3_11.

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Guliani, Anika, Rubbel Singla, Avnesh Kumari, and Sudesh Kumar Yadav. "Liposomal and Phytosomal Formulations." In Nanoscale Materials in Targeted Drug Delivery, Theragnosis and Tissue Regeneration. Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-10-0818-4_4.

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Erdogan, Suna, and Vladimir P. Torchilin. "Gadolinium-Loaded Polychelating Polymer-Containing Tumor-Targeted Liposomes." In Methods in Molecular Biology. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-6591-5_14.

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Conference papers on the topic "Targetted liposome"

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Zhang, Aili, Xipeng Mi, and Lisa X. Xu. "Study of Thermally Targeted Nano-Particle Drug Delivery for Tumor Therapy." In ASME 2008 First International Conference on Micro/Nanoscale Heat Transfer. ASMEDC, 2008. http://dx.doi.org/10.1115/mnht2008-52383.

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The efficacy of cancer chemotherapeutics could be greatly enhanced by thermally targeted nanoparticle liposome drug delivery system. The tumor microvasculature response to hyperthermia and its permeability to the nano-liposomes were studied using the 4T1 mouse model and confocal fluorescence microscopy. Based on the experimental results, a new theoretical model was developed to describe the distributions of both the liposomal and free drug released as liposomes broke in tumor for treatment evaluation. In this model, the tumor was divided into two regions: peripheral and central. The drug effec
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Tartis, Michaelann S., Jan Marik, Azadeh Kheirolomoom, et al. "Pharmacokinetics of Encapsulated Paclitaxel: Multi-Probe Analysis With PET." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176435.

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We have combined two imaging probes and used PET as a means to provide image-based validation for a novel targeted drug delivery system. The first probe was a direct labeling of the drug [18F]fluoropaclitaxel [1–3], which was inserted into various carrier vehicle formulations. The second probe, [18F]fluoro-1,2-dipalmitoyl-sn-glycerol, i.e. [18F]FDP involved radiolabeling the lipid vehicle. Paclitaxel, which is poorly soluble in aqueous media, also has limited solubility and stability in lipophilic environments such as liposomes. Stable association of paclitaxel with the lipid bilayer is affect
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Mulamalla, Hari Chandana R., Maria P. Lambros, and Ying Huang. "Abstract 5514: Targeted liposomes in cancer therapy." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-5514.

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Espelin, C., E. Geretti, S. Coma, et al. "Abstract P3-06-05: Receptor-mediated binding of HER2-targeted antibody-liposomal doxorubicin conjugate MM-302 increases liposome binding, nuclear doxorubicin, DNA damage and efficacy relative to untargeted PEGylated liposomal doxorubicin (PLD/Doxil)." In Abstracts: 2016 San Antonio Breast Cancer Symposium; December 6-10, 2016; San Antonio, Texas. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.sabcs16-p3-06-05.

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Matviykiv, Sofiya, Marzia Buscema, Tamás Mészáros, et al. "Liposomes: bio-inspired nano-containers for physically triggered targeted drug delivery." In SPIE Smart Structures and Materials + Nondestructive Evaluation and Health Monitoring, edited by Mato Knez, Akhlesh Lakhtakia, and Raúl J. Martín-Palma. SPIE, 2017. http://dx.doi.org/10.1117/12.2258378.

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Yokoyama, Tomohisa, Yoichi Osato, Keisuke Miyazawa, et al. "Abstract 2904: EGFR-targeted gold liposome for molecular imaging and therapy on NSCLC cells." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-2904.

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Mriouah, Jihane M., Rae Lynn Nesbitt, Deborah Sosnowski, et al. "Abstract 2192: Fusogenic targeted liposomes as next-generation nanomedicine for prostate cancer." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-2192.

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Nesbitt, Rae, Desmond Pink, Roy Duncan, and John Lewis. "Abstract 3224: Targeted non-invasive therapy of prostate cancer using fusogenic liposomes." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-3224.

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Omata, Daiki, Yoichi Negishi, Yoko Endo-Takahashi, et al. "Ultrasound-targeted Bubble Liposome Destruction Enhances AG73-mediated Gene Transfer by Improvement of Intracellular Trafficking." In 10TH INTERNATIONAL SYMPOSIUM ON THERAPEUTIC ULTRASOUND (ISTU 2010). AIP, 2011. http://dx.doi.org/10.1063/1.3607927.

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Xia, Zongxin, Hong Yang, Fei Li, Shulai Zhu, and Ying Xing. "The research of targeted liposome embedding brain-derived neurotrophic factor through the blood–brain barrier." In International Conference on Modern Engineering Soultions for the Industry. WIT Press, 2014. http://dx.doi.org/10.2495/mesi140972.

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Reports on the topic "Targetted liposome"

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Onyuksel, Hayat. Tc-99m Labeled and VIP Receptor Targeted Liposomes for Effective Imaging of Breast Cancer. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada433960.

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