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Relevant bibliographies by topics / Targetting / Dissertations / Theses

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Dissertations / Theses on the topic 'Targetting'

Author: Grafiati

Published: 4 June 2021

Last updated: 17 February 2022

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1

Panda, Binaya Ranjan. "Retroviral targetting." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301419.

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2

Gavathiotis, Evripidis. "Drug-targetting of duplex and quadruplex DNA." Thesis, University of Nottingham, 2002. http://eprints.nottingham.ac.uk/27683/.

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This thesis investigates structural and dynamic properties of drug recognition mechanisms to duplex and quadruplex DNA using primarily high field NMR techniques and molecular dynamics simulations. The mechanism of co-operative binding of Hoechst 33258 to the DNA minor groove of duplexes that contain two binding sites such as d(CTTTTGCAAAAG)2, d(GAAAAGCTTTC)2 and d(CTTTTGGCCAAAAG)2 has been studied. NMR and other titration techniques have evidenced co-operative binding and no detection of an intermediate 1:1 complex. High-resolution NMR structure determination showed no evidence of direct conta

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3

Crick, David. "An investigation into the targetting of U.K. export assistance." Thesis, Cardiff University, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.361266.

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4

Oxley, Camilla Lisa. "Post translational modifications in integrin signalling and proteasome targetting." Thesis, University of Oxford, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.526097.

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5

Hay, Nicole Aviva. "The adaptation of an in vitro coupled transcription-translation-translocation system for the study of protein translocation in Escherichia coli by use of crosslinkers." Thesis, University of Liverpool, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.316481.

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6

Shoberu, Karoline Adesola. "The biosynthesis and synthesis of carbocyclic nucleosides." Thesis, University of Exeter, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.385737.

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7

Parlett, Terry Brian. "Ribozymes targetting JNK1 and JNK2 isoforms of the map kinase cascade." Thesis, King's College London (University of London), 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.413649.

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8

Clarkson, George H. D. "Immunological and biosynthetic studies on two mitochondrial dehydrogenases." Thesis, University of Glasgow, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.280033.

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9

Sopwith, William. "The cloning and characterization of the 3'-nucleotidase/nuclease in Leishmania Mexicana." Thesis, University of Liverpool, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367753.

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10

Westgate, Stephen E. "An information system for estimating, targetting and planning in small building firms." Thesis, Sheffield Hallam University, 1986. http://shura.shu.ac.uk/20517/.

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This thesis outlines the basic problems relating to estimating, targetting and planning functions in small building firms and a possible solution. It was found that information for these functions was rarely integrated and was derived from different sources. It was therefore suspect in terms of accuracy. Four case studies were undertaken and the firms were investigated and analysed in terms of their logical and physical organisation and management systems. Their basic problems were the lack of control of costs, slow feedback of information, low labour productivity and a shortage of staff to ca

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11

Sun, Mei-Yi. "Proteins involved in the trafficking and targetting of MHC class II related molecules." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302394.

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12

Khelefi, Amel Feriel. "Haemoxugenase in tumours and its role in vascular targetting with combretastatin A4 phosphate." Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.408591.

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13

Khan, Saiqa. "Investigation of the in-vivo biodistribution and tumour-targetting properties of radiolabelled human lactoferrin." Thesis, University of Nottingham, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.403453.

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14

Zariquiey, Armando E. Gonzalez. "Evaluation of a control programme for Taenia solium cysticercosis targetting human and porcine health." Thesis, University of Reading, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.363405.

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15

Drake, Thomas. "Priority-setting for malaria control and elimination in Myanmar." Thesis, University of Oxford, 2017. http://ora.ox.ac.uk/objects/uuid:f3c77e6e-6c25-4aa9-9de0-4a7bc94826e2.

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In Myanmar, Plasmodium falciparum malaria is important because of both the burden of disease and the emergence of parasites resistant to artemisinin-based therapies. In 2012, concomitant with the lifting of international economic sanctions, funding for malaria control and elimination in Myanmar rose significantly. The University of Oxford was asked to support priority setting by assessing the relative cost-effectiveness of insecticide- treated bed nets and community health workers, particularly with respect to planning in the Myanmar Artemisinin Resistance Containment region along the east of

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16

Morello, Jean-Pierre. "Mutations leading to misfolding and endoplasmic reticulum retention of the V2 vasopressin receptor, assessing pharmacologically-assisted folding and targetting." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/NQ62099.pdf.

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17

Finley, Jennifer. "Cell Fate Maintenance and Presynaptic Development in the Drosophila Eye." Thesis, University of Oregon, 2013. http://hdl.handle.net/1794/13254.

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Neurons in the central nervous system are typically not replaced and must therefore maintain their choice of fate and their synaptic connections throughout the life of an organism. I have used Drosophila genetics to analyze genes that prevent neurons from switching fates and allow them to form synapses onto target neurons. The Drosophila fly eye is composed of approximately 750 ommatidia, each comprising eight photoreceptor neurons (R1-R8) surrounded by non-neuronal accessory cells. These photoreceptor neurons undergo a well-defined developmental specification process and form synapses at defi

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18

Fullerton, Graham. "Hyperthermia as a Cancer Treatment- From Theory to Practice." Scholarship @ Claremont, 2018. http://scholarship.claremont.edu/cmc_theses/1824.

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Using iron super-paramagnetic and ferromagnetic nanoparticles composed of Fe3O4 molecules, scientists analyze the effectiveness and practicality of this new treatment theory, hyperthermia. The problems of magnetic particle density, isothermal barriers/cellular cooling thresholds, and nanoparticle specific targeting are addressed in this review. Iron magnetic nanoparticles were chosen due to their relatively low biological reactivates and lack of subsequent cellular toxicity. However, there are significant heating problems associated with these magnetic nanoparticles due to their relative size

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19

Hradílek, Ondřej. "Automatické ověření zaměřovací funkce letecké satelitní antény." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2014. http://www.nusl.cz/ntk/nusl-220977.

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This diploma thesis provides an overview and basic principles of satellite communication systems. Further is description of specific aerial satellite communication system ARINC 791. The practical part includes proposals of the system for automated verification targeting functionality of an air satellite antenna, which has been carried out in Honeywell laboratory conditions. The selected implementation is realized and used for automated verification targeting functionality of an air satellite antenna. The results are graphically evaluated.

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20

Monot, Clément. "La particule ribonucléoprotéique de l'élément L1 humain : spécificité de l'activité transcriptase inverse et partenaires cellulaires." Thesis, Nice, 2013. http://www.theses.fr/2013NICE4062.

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Les éléments LINE-1 (L1) sont les seuls éléments transposables autonomes et actifs, constituant 20% de notre ADN. Ils prolifèrent via un intermédiaire ARN dans un processus appelé rétrotransposition. Les L1s encodent deux protéines, ORF1p et ORF2p, qui s’associent avec l’ARN du L1 pour former une particule ribonucléoprotéique (RNP), constituant l’intermédiaire fonctionnel de la rétrotransposition. Les L1s « sautent » activement dans les cellules germinales, les cellules souches embryonnaires et dans l’embryon précoce, conduisant occasionnellement à des maladies génétiques. Ils sont également e

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21

Verhille, Marc. "Conception, élaboration et caractérisation photophysiques et biochimiques de molécules photoactivables pour la thérapie photodynamique." Thesis, Université de Lorraine, 2012. http://www.theses.fr/2012LORR0194/document.

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L'angiogenèse est une étape clef dans le processus de progression tumorale. Elle est caractérisée par une surexpresssion d'un grand nombre de métalloprotéinases matricielles (MMP). Parmis ces MMP, les gélatinases (MMP-2 et MMP-9) sont connues pour jouer un rôle important dans l'angiogenèse tumorale et la croissance de nombreux cancers. Les "Photodynamic Molecular Beacon" (PMB) sont des constructions moléculaires qui peuvent être utilisées dans le traitement de cancers en associant un photosensibilisateur (PS) de type chlorine et un inhibiteur d'états excités, aussi appelé "Quencher", liés par

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22

Gonsalves, Danielle. "shRNAs targetting LRP mRNA as alternative therapeutic tools for Alzheimer's disease treatment." Thesis, 2013. http://hdl.handle.net/10539/12908.

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A!dissertation submitted to the Faculty of Science, University of the Witwatersrand, Johannesburg, in the fulfillment of the requirements for the degree of Master of Science. 2013.<br>Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease affecting in excess of 26.6 million individuals globally. The neuropathological features of AD include extracellular deposition of amyloid beta (Aβ) plaques and intracellular neurofibrillary tangle formation. The cellular prion protein (PrPC) regulates the amyloidogenic cleavage pathway involved in Aβ shedding and interacts with the

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23

Oliveira, Joana Raquel Duarte Moitinho de. "Targetting β-Cell Death in Type 2 Diabetes: The Effect Of Sodium Tungstate In Irs2 Knockout Mice". Doctoral thesis, 2018. http://hdl.handle.net/10316/82828.

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24

Athanasopoulos, Michael, Hassan Ugail, and Castro Gabriela Gonzalez. "On the development of an Interactive talking head system based on the use of PDE-based parametric surfaces." 2011. http://hdl.handle.net/10454/4977.

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Yes<br>In this work we propose a talking head system for animating facial expressions using a template face generated from Partial Differen- tial Equations (PDEs). It uses a set of preconfigured curves to calculate an internal template surface face. This surface is then used to associate various facial features with a given 3D face object. Motion retargeting is then used to transfer the deformations in these areas from the template to the target object. The procedure is continued until all the expressions in the database are calculated and transferred to the target 3D human face object. Additi

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25

Auerbach-Ziogas, Ilia. "An Exploration of Cell Receptor Labeling via Dark Field Imaging and Quantifying Densely Bound SERS Labels via Raman Signal Strength." Thesis, 2013. http://hdl.handle.net/1807/35583.

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Two experiments explore the application of plasmonic nanoparticles to cellular pathology. The first devised a platform by which gold-silver nanoparticles act as differentiable labels for cell surface receptors under dark field imaging. By conjugating particles of various constitutions with receptor-targeting antibodies, particles scatter characteristically according to their plasmon peak. The second experiment programmed receptor placement via the patterning of two substrates and used the binding of SERS nanoparticles to explore the quantification of such targets at high-density. On one substr

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