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Journal articles on the topic 'Tat imprints'

Author: Grafiati

Published: 25 July 2024

Last updated: 31 July 2025

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1

Yusim, Karina, Can Kesmir, Brian Gaschen, et al. "Clustering Patterns of Cytotoxic T-Lymphocyte Epitopes in Human Immunodeficiency Virus Type 1 (HIV-1) Proteins Reveal Imprints of Immune Evasion on HIV-1 Global Variation." Journal of Virology 76, no. 17 (2002): 8757–68. http://dx.doi.org/10.1128/jvi.76.17.8757-8768.2002.

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ABSTRACT The human cytotoxic T-lymphocyte (CTL) response to human immunodeficiency virus type 1 (HIV-1) has been intensely studied, and hundreds of CTL epitopes have been experimentally defined, published, and compiled in the HIV Molecular Immunology Database. Maps of CTL epitopes on HIV-1 protein sequences reveal that defined epitopes tend to cluster. Here we integrate the global sequence and immunology databases to systematically explore the relationship between HIV-1 amino acid sequences and CTL epitope distributions. CTL responses to five HIV-1 proteins, Gag p17, Gag p24, reverse transcrip

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Gouws, T. "Die transkripsielees van T.T. Cloete." Literator 10, no. 3 (1989): 31–47. http://dx.doi.org/10.4102/lit.v10i3.834.

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In a transcriptual approach to the literary discourse, the text as artefact is regarded as a creation of the scriptor. The artificiality of the poetics implies conscious or unconscious structuring - Cloete terms it dreamful thinking (“die dromende denke”) - by inevitably exploiting language conventions and the poetic devices, the sole purpose being that the organised composition can be the only (as well as measurable) indication of authorial intention. Likewise, in as far as language presents the relevant possibilities, authorial intention is imprinted upon the textual composition or is transp

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3

Liu, Chen, Zixuan Dong, Li Huang, et al. "TagSleep3D." Proceedings of the ACM on Interactive, Mobile, Wearable and Ubiquitous Technologies 8, no. 1 (2024): 1–28. http://dx.doi.org/10.1145/3643512.

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Sleep posture plays a crucial role in maintaining good morpheus quality and overall health. As a result, long-term monitoring of 3D sleep postures is significant for sleep analysis and chronic disease prevention. To recognize sleep postures, traditional methods either use cameras to record image data or require the user to wear wearable devices or sleep on pressure mattresses. However, these methods could raise privacy concerns and cause discomfort during sleep. Accordingly, the RF (Radio Frequency) based method has emerged as a promising alternative. Despite most of these methods achieving hi

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Harold, E. E., D. M. T. Chandramali, P. D. K. Thiranagama, K. Wijesinghe, and C. S. P. Sosai. "Diagnostic accuracy of rapid stain technique in touch imprint cytology of axillary sentinel lymph nodes." Journal of Diagnostic Pathology 18, no. 2 (2023): 18. https://doi.org/10.4038/jdp.v18i2.7889.

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Introduction and objective: Touch imprint cytology (TIC) is a well-recognized technique in the intraoperative assessment of axillary sentinel lymph nodes (ASLN) for metastases. Rapid stain technique (RST) can reduce TIC turnaround time (TAT). The objective is to determine the diagnostic accuracy of rapid stain TIC.Methodology: Data was retrieved and analysed from the departmental database. ASLN reports from January 2019 to November 2022 were reviewed. ASLN received for TIC was subjected to a validated RST, in which, the TIC smear was fixed and stained for one minute in 95% ethyl alcohol and ha

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Lafuente-González, Elsa, Miriam Guadaño-Sánchez, Idoia Urriza-Arsuaga, and Javier Lucas Urraca. "Core-Shell Magnetic Imprinted Polymers for the Recognition of FLAG-Tagpeptide." International Journal of Molecular Sciences 24, no. 4 (2023): 3453. http://dx.doi.org/10.3390/ijms24043453.

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FLAG® tag (DYKDDDDK) is a small epitope peptide employed for the purification of recombinant proteins such as immunoglobulins, cytokines, and gene regulatory proteins. It provides superior purity and recoveries of fused target proteins when compared to the commonly used His-tag. Nevertheless, the immunoaffinity-based adsorbents required for their isolation are far more expensive than the ligand-based affinity resin used in combination with the His-tag. In order to overcome this limitation we report herein the development of molecularly imprinted polymers (MIPs) selective to the FLAG® tag. The

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Hoh, JFY. "Myogenic Regulation of Mammalian Skeletal Muscle Fibres." Physiology 6, no. 1 (1991): 1–6. http://dx.doi.org/10.1152/physiologyonline.1991.6.1.1.

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Motor nerves can only modify the phenotype of muscle fibres within a myogenically determined range. The particular range of a given fibre is an intrinsic property of that fibre, depending on the type of muscle (limb or jaw) and the specific tag imprinted upon it during development.

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Balčius, Jonas. "TAUTOS IR TAUTINĖS IŠTIKIMYBĖS PROBLEMA A. MACEINOS IR J. GIRNIAUS VEIKALUOSE." Problemos 73 (January 1, 2008): 179–96. http://dx.doi.org/10.15388/problemos.2008.0.2008.

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Straipsnyje aptariami ir įvertinami Antano Maceinos (1908–1987) ir Juozo Girniaus (1915–1994) veikalai, skirti lietuvių tautos kultūrinio ir politinio išliekamumo klausimams sovietų okupacijos ir tautinės emigracijos sąlygomis. Parodoma, jog šiame darbe cituojami minėtų lietuvių filosofų darbai tebėra vieni reikšmingiausių ir teoriškai brandžiausių veikalų, parašytų ne tik emigracijoje, bet ir per visą Lietuvos filosofijos istoriją. Tai reiškia, kad jie neprarado savo konceptualiojo – teorinio ir praktinio – aktualumo ir mūsų laikais, nes Lietuvos istorija, kaip žinoma, turi didesnių abejonių

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Madsen, Storm. "Archiving Our Bodies:." Kvinder, Køn & Forskning 37, no. 2 (2025): 14. https://doi.org/10.7146/kkf.v37i2.141262.

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This article analyses artworks by three non-binary or trans masculine artists: Kris Grey, No title (2019), Emmett Ramstad, The good ones (2006), and Marie Ahlberg Andersen, My Dick Clit has many forms (2022). I look at the corporeal traces the artworks display: wound scabs, blood drops, and crotch imprints, and find that they present a proof of trans becoming which, I would like to suggest, counters hegemonic narratives of transition and disturbs the notion of proof in relation to trans life; to highlight instead, the slowness, temporal multiplicity, and volatile uncapturability of trans embod

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Beezley, William H. "Juan O'Gorman, Daniel Cosío Villegas, and the Mexican Historical Profession: An Interview with Josefina Zoraida Vázquez." Americas 67, no. 2 (2010): 253–68. http://dx.doi.org/10.1353/tam.2010.0007.

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Professor Josefina Zoraida Vázquez has made an indelible imprint on the discipline of the history of Mexico. Her publications have provided an analysis of the Mexican experience through such diverse themes as the U.S. invasion (1846-1848), the evolution of national education programs, and the struggles to establish federalism and republicanism in the first decades of independence. She has written official textbooks used by all Mexican school children, appeared on numerous television programs, taught dozens of doctoral students, and assisted many scholars in both Mexico and the United States. S

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Sutton, Margie N., Gilbert Y. Huang, Xiaowen Liang, et al. "DIRAS3-Derived Peptide Inhibits Autophagy in Ovarian Cancer Cells by Binding to Beclin1." Cancers 11, no. 4 (2019): 557. http://dx.doi.org/10.3390/cancers11040557.

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Autophagy can protect cancer cells from acute starvation and enhance resistance to chemotherapy. Previously, we reported that autophagy plays a critical role in the survival of dormant, drug resistant ovarian cancer cells using human xenograft models and correlated the up-regulation of autophagy and DIRAS3 expression in clinical samples obtained during “second look” operations. DIRAS3 is an imprinted tumor suppressor gene that encodes a 26 kD GTPase with homology to RAS that inhibits cancer cell proliferation and motility. Re-expression of DIRAS3 in ovarian cancer xenografts also induces dorma

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Gómez-Arribas, Lidia N., Javier L. Urraca, Elena Benito-Peña, and María C. Moreno-Bondi. "Tag-Specific Affinity Purification of Recombinant Proteins by Using Molecularly Imprinted Polymers." Analytical Chemistry 91, no. 6 (2019): 4100–4106. http://dx.doi.org/10.1021/acs.analchem.8b05731.

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Liu, Jinxin, Xiaoba Wu, Xuefeng Yao, Ronald Yu, Philip J. Larkin, and Chun-Ming Liu. "Mutations in the DNA demethylase OsROS1 result in a thickened aleurone and improved nutritional value in rice grains." Proceedings of the National Academy of Sciences 115, no. 44 (2018): 11327–32. http://dx.doi.org/10.1073/pnas.1806304115.

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The rice endosperm, consisting of an outer single-cell layer aleurone and an inner starchy endosperm, is an important staple food for humans. While starchy endosperm stores mainly starch, the aleurone is rich in an array of proteins, vitamins, and minerals. To improve the nutritional value of rice, we screened for mutants with thickened aleurones using a half-seed assay and identified thick aleurone 2–1 (ta2-1), in which the aleurone has 4.8 ± 2.2 cell layers on average. Except for starch, the contents of all measured nutritional factors, including lipids, proteins, vitamins, minerals, and die

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Zhu, Shu-Yan, Yuan-Long Li, Kwai-Man Luk, and Stella W. Pang. "Compact High-Gain Si-Imprinted THz Antenna for Ultrahigh Speed Wireless Communications." IEEE Transactions on Antennas and Propagation 68, no. 8 (2020): 5945–54. http://dx.doi.org/10.1109/tap.2020.2986863.

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14

Albright, Ann Cooper. "Matters of Tact: Writing History from the Inside Out." Dance Research Journal 36, no. 1 (2004): 11–26. http://dx.doi.org/10.1017/s0149767700007543.

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Long before I became a committed academic, long before I was a college professor teaching dance history, long before terminal degrees and professional titles, I chanced upon an exhibition of early dance photographs at the Rodin Museum in Paris. I bought the small catalogue, and from time to time I would page through the striking black and white images searching for dancing inspiration. I always paused at a certain one of Loïe Fuller. There she is, radiant in the sunlight of Rodin's garden, chest open, arms spread like great wings, running full force towards the camera. It is an image of a stro

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15

Li, Senwu, Kaiguang Yang, Jianxi Liu, Bo Jiang, Lihua Zhang, and Yukui Zhang. "Surface-Imprinted Nanoparticles Prepared with a His-Tag-Anchored Epitope as the Template." Analytical Chemistry 87, no. 9 (2015): 4617–20. http://dx.doi.org/10.1021/ac5047246.

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16

Salazar-Gonzalez, Jesus F., Maria G. Salazar, Brandon F. Keele, et al. "Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection." Journal of Experimental Medicine 206, no. 6 (2009): 1273–89. http://dx.doi.org/10.1084/jem.20090378.

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Identification of full-length transmitted HIV-1 genomes could be instrumental in HIV-1 pathogenesis, microbicide, and vaccine research by enabling the direct analysis of those viruses actually responsible for productive clinical infection. We show in 12 acutely infected subjects (9 clade B and 3 clade C) that complete HIV-1 genomes of transmitted/founder viruses can be inferred by single genome amplification and sequencing of plasma virion RNA. This allowed for the molecular cloning and biological analysis of transmitted/founder viruses and a comprehensive genome-wide assessment of the genetic

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17

Wang, Xiaohui, Chang Liu, Yichuan Cao, Lin Cai, Haiyang Wang, and Guozhen Fang. "A Turn-Off Fluorescent Biomimetic Sensor Based on a Molecularly Imprinted Polymer-Coated Amino-Functionalized Zirconium (IV) Metal–Organic Framework for the Ultrasensitive and Selective Detection of Trace Oxytetracycline in Milk." Foods 12, no. 11 (2023): 2255. http://dx.doi.org/10.3390/foods12112255.

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Developing sensitive and effective methods to monitor oxytetracycline residues in food is of great significance for maintaining public health. Herein, a fluorescent sensor (NH2-UIO-66 (Zr)@MIP) based on a molecularly imprinted polymer-coated amino-functionalized zirconium (IV) metal–organic framework was successfully constructed and first used for the ultrasensitive determination of oxytetracycline. NH2-UIO-66 (Zr), with a maximum emission wavelength of 455 nm under 350 nm excitation, was prepared using a microwave-assisted heating method. The NH2-UIO-66 (Zr)@MIP sensor with specific recogniti

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18

Gómez-Arribas, Lidia N., María del Mar Darder, Nuria García, Yoel Rodriguez, Javier L. Urraca, and María C. Moreno-Bondi. "Hierarchically Imprinted Polymer for Peptide Tag Recognition Based on an Oriented Surface Epitope Approach." ACS Applied Materials & Interfaces 12, no. 43 (2020): 49111–21. http://dx.doi.org/10.1021/acsami.0c14846.

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19

Bennahum, David A. "Encounters With Death." Cambridge Quarterly of Healthcare Ethics 5, no. 1 (1996): 7–9. http://dx.doi.org/10.1017/s0963180100006678.

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I never saw a dead body until my first anatomy class. Today those who have willed their bodies to science receive letters of gratitude, visit with our students, and have their names put up on memorial plaques; but 37 years ago our subjects were derelicts and anonymous old men found dead in flop house hotels. George C, his name written on a tag tied to one toe, lay stretched out on one of the six dissecting tables in the anatomy laboratory that autumn morning when 1 was 22 and beginning medical school. I remember hesitating at the door and then joining my four partners at Mr. C.'s side, trepida

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Koeve, W., O. Duteil, A. Oschlies, P. Kähler, and J. Segschneider. "Methods to evaluate CaCO<sub>3</sub> cycle modules in coupled global biogeochemical ocean models." Geoscientific Model Development 7, no. 5 (2014): 2393–408. http://dx.doi.org/10.5194/gmd-7-2393-2014.

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Abstract. The marine CaCO3 cycle is an important component of the oceanic carbon system and directly affects the cycling of natural and the uptake of anthropogenic carbon. In numerical models of the marine carbon cycle, the CaCO3 cycle component is often evaluated against the observed distribution of alkalinity. Alkalinity varies in response to the formation and remineralization of CaCO3 and organic matter. However, it also has a large conservative component, which may strongly be affected by a deficient representation of ocean physics (circulation, evaporation, and precipitation) in models. H

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Koeve, W., O. Duteil, A. Oschlies, P. Kähler, and J. Segschneider. "Evaluating CaCO<sub>3</sub>-cycle modules in coupled global biogeochemical ocean models." Geoscientific Model Development Discussions 6, no. 4 (2013): 6117–55. http://dx.doi.org/10.5194/gmdd-6-6117-2013.

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Abstract. The marine CaCO3 cycle is an important component of the oceanic carbon system and directly affects the cycling of natural and the uptake of anthropogenic carbon. In numerical models of the marine carbon cycle, the CaCO3 cycle component is often evaluated against the observed distribution of alkalinity. Alkalinity varies in response to the formation and remineralisation of CaCO3 and organic matter. However, it also has a large conservative component, which may strongly be affected by a deficient representation of ocean physics (circulation, evaporation, and precipitation) in models. H

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22

Turan, Eylem. "His‐Tag‐Epitope Imprinted Thermoresponsive Magnetic Nanoparticles for Recognition and Separation Thyroid Peroxidase Antigens from Whole Blood Samples." ChemistrySelect 3, no. 42 (2018): 11963–69. http://dx.doi.org/10.1002/slct.201801557.

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23

Chang, Wenbo. "Performing the Role of Playwright: Jia Zhongming's Sanqu Songs in the Supplement to The Register of Ghosts." Journal of Chinese Literature and Culture 8, no. 1 (2021): 59–88. http://dx.doi.org/10.1215/23290048-8898622.

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Abstract This article investigates how sanqu composition modifies the social contract of poetic composition in how a text is mediated between authorship and social identity, through a close analysis of Jia Zhongming's sanqu songs written in the supplement to The Register of Ghosts. It challenges the conventional reading of Jia's songs as reliable sources of biographical information on individual playwrights to whom those songs are dedicated and argues instead that, if read together as a whole, they represent a catalog of various personas Jia constructs for the social role of playwright. The au

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Tari, Ezra, and Talizaro Tafonao. "Pendidikan Anak dalam Keluarga Berdasarkan Kolose 3:21." Kurios 5, no. 1 (2019): 24. http://dx.doi.org/10.30995/kur.v5i1.93.

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This article aimed to describe the education of children in the family based on Colossians 3:21. This study used a sociological criticism approach by conducting a study of the text of Colossians 3:21 to analyze the Bible's view of children's education in the family. The conclusion of this textual study is educating children without violence. Paul reminded fathers in educating children to prioritize love as the basis for education in the family. The love of a father will be reflected in the lives of every child through communication and imprinted in an attitude of obedience and respect for pare

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DeClerck, Jonathan C., Zain E. Wade, Nathan R. Reeves, et al. "Influence of Megasphaera elsdenii and feeding strategies on feedlot performance, compositional growth, and carcass parameters of early weaned, beef calves." Translational Animal Science 4, no. 2 (2020): 863–75. http://dx.doi.org/10.1093/tas/txaa031.

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Abstract Simmental–Angus calves [n = 135; 72 steers and 63 heifers; body weight (BW) = 212.4 kg ± 36.1] were early weaned (~5 mo) to evaluate multiple feeding regimens (conventional vs. aggressive energy diets ± Megasphaera elsdenii NCIMB 41125 (M. elsdenii culture (MEC); Lactipro Advance; MS Biotec Inc., Wamego, KS) in order to elucidate the optimal development strategy. Objectives were measured by tracking the effects of caloric density and oral drenching of growing phase performance and subsequent carcass traits. The 72-d experiment featured three groups: 1) control (CON), fed exclusively a

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Senyk, Alla. "PERSONAL DEVELOPMENT OF FUTURE SOCIAL WORKERS: FROM THEORY TO PRACTICE." Social work and social education, no. 1(12) (April 30, 2024): 278–83. http://dx.doi.org/10.31499/2618-0715.1(12).2024.305362.

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The relevance of the topic is revealed through the definition of the essence of professional and personal development of future social workers. The author indicates the stages of professional development of an individual, defining this process as long and dynamic at the same time, which involves the individual passing through seven stages: growth; clarification; stages of professional adaptation and stabilization; stages of development of professionalism and pseudo-professionalism; as well as the final stage of post-professionalism. Among the mandatory qualities and skills of a social worker a

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Abdul Azeez, K. K., Prasanta K. Patro, T. Harinarayana, and S. V. S. Sarma. "Magnetotelluric imaging across the tectonic structures in the eastern segment of the Central Indian Tectonic Zone: Preserved imprints of polyphase tectonics and evidence for suture status of the Tan Shear." Precambrian Research 298 (September 2017): 325–40. http://dx.doi.org/10.1016/j.precamres.2017.06.018.

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Guo, Ying, Guanqing Yuan, Xuelian Hu, Jinni Zhang, and Guozhen Fang. "A High-Luminescence Biomimetic Nanosensor Based on N, S-GQDs-Embedded Zinc-Based Metal–Organic Framework@Molecularly Imprinted Polymer for Sensitive Detection of Octopamine in Fermented Foods." Foods 11, no. 9 (2022): 1348. http://dx.doi.org/10.3390/foods11091348.

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In this study, a novel fluorescent molecularly imprinted nanosensor (N, S-GQDs@ZIF-8@MIP) based on the nitrogen and sulfur co-doped graphene quantum dots decorated zeolitic imidazolate framework-8 was constructed for the detection of octopamine (OA). Herein, ZIF-8 with a large surface area was introduced as a supporter of the sensing system, which effectively shortened the response time of the sensor. Meanwhile, high green luminescent N, S-GQDs and a maximum emission wavelength of 520 nm under 460 nm excitation and a 12.5% quantum yield were modified on the surface of ZIF-8 as a signal tag tha

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Ramsenthaler, Susanne. "GLOWING EVIDENCE: PHOTOGRAMS – THE DARK SIDE OF PHOTOGRAPHY / SPINDINTIS AKIVAIZDUMAS: FOTOGRAMOS – TAMSIOJI FOTOGRAFIJOS PUSĖ." CREATIVITY STUDIES 5, no. 1 (2012): 32–41. http://dx.doi.org/10.3846/20297475.2012.660548.

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Our ability to instantly read photographs is based on our sense of vision operating at a distance. Within the field of photographic processes however, co exists a very different representation: that of imprint and touch – namely the photogram. The decipherability of photographs to us is almost immediate but photograms work on a different level. They encapsulate the meeting of material and light-sensitive surface and incorporate the mark of authenticity, while producing an image which may not be immediately “read”. This paper constitutes a metaphysical inquiry into the perception and ontology o

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Kretzschmann, F. "Food Additive User's Handbook. Herausgegeben von J. Smith. 286 Seiten, zahlr. Tab. Blackie and Son Ltd, Glasgow, London, 1991 (veröffentlicht in den USA von AVI, an imprint of Van Nostrand Reinhold, New York). Preis: 65, - £." Food / Nahrung 35, no. 8 (1991): 890. http://dx.doi.org/10.1002/food.19910350818.

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Brückner, J. "Developments in Oils and Fats. Herausgegeben von R. J. Hamilton. 269Seiten, zahlr. Abb. und Tab. Blackie Academic and Professional. An Imprint of Chapman and Hall, London, Glasgow, Weinheim. New York. Tokyo, Melbourne. Madras 1994. Preis: 65.– £." Food / Nahrung 39, no. 3 (1995): 253–54. http://dx.doi.org/10.1002/food.19950390328.

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Hermersdörfer, H. "Immobilized Biosystems. Theory and Practical Applications. Herausgegeben von I. A. Veliky und R.J.C. McLean. 342 Seiten, zahlr. Abb. und Tab. Blackie Academic and Professional. An Imprint of Chapman and Hall, London, Glasgow, New York, Tokyo, Melbourne, Madras 1994. Preis: 89,– £." Food / Nahrung 39, no. 2 (1995): 182. http://dx.doi.org/10.1002/food.19950390217.

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Stepanenko, Hanna, and Oleksandr Siehodin. "Orthodontic correction in rodents and hare-like animals: principles and methods of treatment." ScienceRise: Biological Science, no. 1(34) (March 31, 2023): 50–56. http://dx.doi.org/10.15587/2519-8025.2023.276319.

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The aim: Our particular interest in this study is not only the ability to extrapolate the experience of orthodontics of humane medicine for effective orthodontic correction in representatives of the animal world, but also the possibility of using teleroentgenometry and craniometry to study the skull of rodents and hare-like animals for the early preclinical diagnosis of dental disease. Materials and methods. The data of teleroentgenography (TRG), cranio- and gnatometry, biochemistry of connective tissue (GAG, GP, HST), fluoroscopy, densitometric parameters for early subclinical detection

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Hoppe, K. "Processing and Packaging of Heat Preserved Foods. Herausgegeben von J.A.G. Rees und J. Bettison. 250 Seiten, zahlr. Abb. und Tab. Blackie and Son, Glasgow, London 1991 (in den USA veröffentlicht bein AVI, an imprint of Van Norstrand Reinhold, New York). Preis: 55.- £." Food / Nahrung 35, no. 8 (1991): 897–98. http://dx.doi.org/10.1002/food.19910350829.

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Hogart, Amber, Subramanian S. Ajay, Hatice Ozel Abaan, Stacie M. Anderson, Elliott H. Margulies, and David M. Bodine. "Genome-Wide DNA Methylation Patterns Reveal Specific Signatures for HSC, CMP and Erythroblasts." Blood 114, no. 22 (2009): 391. http://dx.doi.org/10.1182/blood.v114.22.391.391.

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Abstract Abstract 391 DNA methylation is a reversible epigenetic modification that is required for proper mammalian development and is proposed to contribute to the pathogenesis of hematologic diseases including leukemia and bone marrow failure syndromes. Elucidating the pathways and genes regulated by DNA methylation during hematopoiesis may reveal new therapeutic targets for disease. Because the phenotype and activity of hematopoietic stem cells (HSC) and hematopoietic progenitor cells of many different lineages have been defined by both in vitro and in vivo assays, hematopoiesis is an excel

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Ahmad, Zeshan, Shahbaz Sharif, Muhammad Ahmad Alrashid, and Muhammad Nadeem. "Personality trait imprints across generations: small family business context." Revista de Gestão, August 15, 2022. http://dx.doi.org/10.1108/rege-08-2021-0155.

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PurposeThe purpose of this study is to investigate how the congruence between predecessor and successor personality traits (PTs) with the values of their small family business (SFB) contributes to a successful succession transition across generations.Design/methodology/approachThe conceptual model method was employed in this investigation, which describes an entity and identifies issues that should be considered in a study (MacInnis, 2011). It involves a form of theorizing that seeks to create a nomological network around the focal concept, to examine and detail the causal linkages and mechani

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Llères, David, Benoît Moindrot, Rakesh Pathak, et al. "CTCF modulates allele-specific sub-TAD organization and imprinted gene activity at the mouse Dlk1-Dio3 and Igf2-H19 domains." Genome Biology 20, no. 1 (2019). http://dx.doi.org/10.1186/s13059-019-1896-8.

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Abstract Background Genomic imprinting is essential for mammalian development and provides a unique paradigm to explore intra-cellular differences in chromatin configuration. So far, the detailed allele-specific chromatin organization of imprinted gene domains has mostly been lacking. Here, we explored the chromatin structure of the two conserved imprinted domains controlled by paternal DNA methylation imprints—the Igf2-H19 and Dlk1-Dio3 domains—and assessed the involvement of the insulator protein CTCF in mouse cells. Results Both imprinted domains are located within overarching topologically

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Yarman, Aysu, Armel F. T. Waffo, Sagie Katz, et al. "A Strep‐tag Imprinted Polymer Platform for Heterogenous Bio(electro)catalysis." Angewandte Chemie, July 9, 2024. http://dx.doi.org/10.1002/ange.202408979.

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Molecularly imprinted polymers (MIPs) are artificial receptors equipped with selective recognition sites for target molecules. One of the most promising‐strategies for protein MIPs relies on the exploitation of short surface‐exposed protein fragments, termed epitopes, as templates to imprint binding sites in a polymer scaffold for a desired protein. However, the lack of high‐resolution structural data of flexible surface‐exposed regions challenges the selection of suitable epitopes. Here, we addressed this drawback by developing a polyscopoletin‐based MIP that recognizes recombinant proteins v

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Yarman, Aysu, Armel F. T. Waffo, Sagie Katz, et al. "A Strep‐tag Imprinted Polymer Platform for Heterogenous Bio(electro)catalysis." Angewandte Chemie International Edition, July 9, 2024. http://dx.doi.org/10.1002/anie.202408979.

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Molecularly imprinted polymers (MIPs) are artificial receptors equipped with selective recognition sites for target molecules. One of the most promising‐strategies for protein MIPs relies on the exploitation of short surface‐exposed protein fragments, termed epitopes, as templates to imprint binding sites in a polymer scaffold for a desired protein. However, the lack of high‐resolution structural data of flexible surface‐exposed regions challenges the selection of suitable epitopes. Here, we addressed this drawback by developing a polyscopoletin‐based MIP that recognizes recombinant proteins v

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Yadav, Gajendra Kumar, Ravi H. Phulware, Ashok Singh, et al. "Comparative Diagnostic Utility of Squash, Scrape and Imprint cytology in Intraoperative Diagnosis of Ovarian Tumours." Acta Cytologica, March 24, 2025, 1–19. https://doi.org/10.1159/000545110.

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Introduction: Intraoperative cytology in ovarian tumors involves collecting cell samples from the ovarian sample sent during surgery and quickly examining them for diagnostic information. Frozen section provides rapid diagnosis to guide intraoperative patient management. The indications of frozen section are identification of tissue, evaluation of margins and identification of lymph nodes metastasis. Aim: To evaluate comparative diagnostic utility of squash smear, scrape smear and imprint cytology with frozen section in intraoperative ovarian tumour. Materials and methods: Intraoperative tissu

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Zhang, Yanmei, Mengdie Fang, Shouye Li, et al. "BTApep-TAT peptide inhibits ADP-ribosylation of BORIS to induce DNA damage in cancer." Molecular Cancer 21, no. 1 (2022). http://dx.doi.org/10.1186/s12943-022-01621-w.

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Abstract Background Brother of regulator of imprinted sites (BORIS) is expressed in most cancers and often associated with short survival and poor prognosis in patients. BORIS inhibits apoptosis and promotes proliferation of cancer cells. However, its mechanism of action has not been elucidated, and there is no known inhibitor of BORIS. Methods A phage display library was used to find the BORIS inhibitory peptides and BTApep-TAT was identified. The RNA sequencing profile of BTApep-TAT-treated H1299 cells was compared with that of BORIS-knockdown cells. Antitumor activity of BTApep-TAT was eval

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Gómez-Arribas, Lidia N., Javier Urraca, Elena Benito-Peña, and María C. Moreno-Bondi. "Tag-specific affinity purification of recombinant proteins by using molecularly imprinted polymers." March 19, 2019. https://doi.org/10.1021/ACS.ANALCHEM.8B05731.

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Epitope tagging is widely used to fuse a known epitope to proteins for which no affinity receptor is available by using recombinant DNA technology. One example is FLAG epitope (DYKDDDDK), which provides better purity and recoveries than the favorite poly histidine tag. However, purification requires using anti-FLAG antibody resins, the high cost and nonreusability of which restrict widespread use. One cost-effective solution is provided by the use of bioinspired anti-FLAG molecularly imprinted polymers (MIPs). This work describes the development of MIPs, based on the epitope approach, synthesi

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Gómez-Arribas, Lidia N., Javier L. Urraca, Elena Benito-Peña, and María C. Moreno-Bondi. "Tag-specific Affinity Purification of Recombinant Proteins by us-ing Molecularly Imprinted Polymers." February 21, 2019. https://doi.org/10.1021/acs.analchem.8b05731.

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Epitope tagging is widely used to fuse a known epitope to proteins for which no affinity receptor is available by using recombinant DNA technology. One example is FLAG epitope (DYKDDDDK), which provides better purity and recoveries than the favorite poly histidine tag. However, purification requires using anti-FLAG antibody resins, the high cost and nonreusability of which restrict widespread use. One cost-effective solution is provided by the use of bioinspired anti-FLAG molecularly imprinted polymers (MIPs). This work describes the development of MIPs, based on the epitope approach, synthesi

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Arabi, Maryam, Abbas Ostovan, Yunqing Wang, et al. "Chiral molecular imprinting-based SERS detection strategy for absolute enantiomeric discrimination." Nature Communications 13, no. 1 (2022). http://dx.doi.org/10.1038/s41467-022-33448-w.

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AbstractChiral discrimination is critical in environmental and life sciences. However, an ideal chiral discrimination strategy has not yet been developed because of the inevitable nonspecific binding entity of wrong enantiomers or insufficient intrinsic optical activities of chiral molecules. Here, we propose an “inspector” recognition mechanism (IRM), which is implemented on a chiral imprinted polydopamine (PDA) layer coated on surface-enhanced Raman scattering (SERS) tag layer. The IRM works based on the permeability change of the imprinted PDA after the chiral recognition and scrutiny of th

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Shahi, Garima, Mohit Kumar, Sonam Kumari, et al. "A detailed lipidomic study of human pathogenic fungi Candida auris." FEMS Yeast Research 20, no. 6 (2020). http://dx.doi.org/10.1093/femsyr/foaa045.

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ABSTRACT The present study is an attempt to determine the lipid composition of Candida auris and to highlight if the changes in lipids can be correlated to high drug resistance encountered in C. auris. For this, the comparative lipidomics landscape between drug-susceptible (CBS10913T) and a resistant hospital isolate (NCCPF_470033) of C. auris was determined by employing high throughput mass spectrometry. All major groups of phosphoglycerides (PGL), sphingolipids, sterols, diacylglycerols (DAG) and triacylglycerols (TAG), were quantitated along with their molecular lipid species. Our analyses

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Radfar, Rahil, Eda Akin, Ekin Sehit, et al. "Synthesis and characterization of core–shell magnetic molecularly imprinted polymer nanocomposites for the detection of interleukin-6." Analytical and Bioanalytical Chemistry, October 16, 2024. http://dx.doi.org/10.1007/s00216-024-05536-x.

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AbstractInterleukin-6 (IL-6) belongs to the cytokine family and plays a vital role in regulating immune response, bone maintenance, body temperature adjustment, and cell growth. The overexpression of IL-6 can indicate various health complications, such as anastomotic leakage, cancer, and chronic diseases. Therefore, the availability of highly sensitive and specific biosensing platforms for IL-6 detection is critical. In this study, for the first time, epitope-mediated IL-6-specific magnetic molecularly imprinted core–shell structures with fluorescent properties were synthesized using a three-s

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Paul, Deepjyoti, Jyoti Verma, Shakti Kumar, et al. "A rapid point-of-care population-scale dipstick assay to identify and differentiate SARS-CoV-2 variants in COVID-19-positive patients." Frontiers in Microbiology 15 (October 21, 2024). http://dx.doi.org/10.3389/fmicb.2024.1459644.

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Delta and Omicron variants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) are remarkably contagious, and have been recognized as variants of concern (VOC). The acquisition of spontaneous substitutions or insertion–deletion mutations (indels) in the spike protein-encoding gene substantially increases the binding affinity of the receptor binding domain (RBD)-hACE2 complex and upsurges the transmission of both variants. In this study, we analyzed thousands of genome sequences from 30 distinct SARS-CoV-2 variants, focusing on the unique nucleic acid signatures in the spike gene sp

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Abdelshakour, Mohamed A., Khaled Attala, Ahmed Elsonbaty, et al. "Eco-friendly UV-spectrophotometric methods employing magnetic nano-composite polymer for the extraction and analysis of sexual boosters in adulterated food products: Application of computer-aided design." Journal of AOAC International, July 14, 2023. http://dx.doi.org/10.1093/jaoacint/qsad084.

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Abstract Backgrounds Solid phase extraction (SPE) techniques based on computationally designed magnetic-based multi-targeting molecular imprinted polymer (MT-MIP) and combined with UV spectrophotometric approaches provide advantages in the examination of counterfeit samples. Objective The current work describes an innovative and sustainable methodology for the simultaneous determination of tadalafil (TAD) and dapoxetine hydrochloride (DAP) in counterfeited honey and instant coffee aphrodisiac products utilizing a SPE exploiting MT-MIP. Besides, an innovative UV spectrophotometric method capabl

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Wu, Xudong, and Tingting Liu. "Insights into the evolution and regulation of miRNAs from the view of their DNA replication temporal domains." Frontiers in Genetics 16 (June 23, 2025). https://doi.org/10.3389/fgene.2025.1544802.

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IntroductionThe DNA replication of eukaryotes proceeds in a defined temporal sequence known as the replication timing (RT) program. A recent study revealed that the early- and late-replication temporal domains have different DNA mutation patterns and that the late-replicating sequences have a substitution pattern biased towards A and T. It raises the interesting question of how the miRNAs in the late-replication domain cope with the mutation bias caused by RT.MethodsIn this study, we characterized the genomic distribution of pre-miRNAs in relation to DNA replication timing, and identified 362

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Furuya, Akira, and Joe D. Cuchiaro. "Improvement of Hydrogen Degradation in Pt/SrBi2Ta2-xNbxO9/Pt Capacitor." MRS Proceedings 574 (1999). http://dx.doi.org/10.1557/proc-574-353.

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AbstractFerroelectric SrBi2(Ta1-xNbx)2O9 (SBTN) thin films are under evaluation for IC memory applications. It has been reported that SrBi2(Ta1-xNbx)2O9 has higher fatigue endurance and imprint resistance than other common ferroelectric materials such as lead zirconate titanate (PZT). One of the most important technical issues for integrating ferroelectric oxide materials into IC memory applications is the degradation of ferroelectric capacitor properties from the oxide reduction from hydrogen. Hydrogen annealing processes performed to terminate dangling bonds in silicon, or, elevated temperat

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