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Journal articles on the topic 'TB clinical profile'

Author: Grafiati

Published: 4 June 2021

Last updated: 16 February 2022

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1

Shrestha, Umid Kumar, Dinesh Shrestha, Ramila Shrestha, and Arnab Ghosh. "Clinical profile of 103 patients with abdominal tuberculosis in Nepal." Journal of Advances in Internal Medicine 4, no. 2 (2017): 51–56. http://dx.doi.org/10.3126/jaim.v4i2.16896.

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Background and aims: The nonspecific clinical features of abdominal tuberculosis (TB) have made its diagnosis difficult, which can lead to the poor outcome in patients who are not able to receive early treatment. Hence, the aim of our study was to determine the clinical profile of abdominal TB in the patients of Nepal.Methods: This is a prospective observational study in which 103 patients with abdominal TB were analyzed for clinical profiles from May 2010 to April 2015. All diagnosed patients received anti-tubercular treatment (ATT) and were followed up at 1 and 6 months of ATT.Results: Among

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Nirmala, M., and V. Narmadha. "A study on clinical profile of tuberculosis in HIV children." International Journal of Contemporary Pediatrics 6, no. 4 (2019): 1506. http://dx.doi.org/10.18203/2349-3291.ijcp20192169.

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Background: Children born to Human immunodeficiency virus (HIV) positive parents who are not infected with tuberculosis (TB) themselves, are also at higher risk of acquiring TB because of exposure. The source of transmission of TB to a child is usually an adult with sputum-smear positive PTB. To evaluate the clinical, bacteriological and radiological pattern of TB in HIV seropositive children in correlation with CD4 count.Methods: This study was conducted over a period of 12 months from May 2008- April 2009 at GMKMCH Salem. 100 children screened positive for HIV at voluntary counselling and te

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Borkar, Mangala S., Anil Shrinivasrao Joshi, Akshay Arvind Kashid, Chaya Ganpat Gawale, Rohit Dharmaraj Kakade, and Hemant Nanda Chimote. "Clinical profile of 128 HIV positive cases with abdominal tuberculosis." International Journal of Scientific Reports 2, no. 1 (2016): 18. http://dx.doi.org/10.18203/issn.2454-2156.intjscirep20160089.

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<p class="abstract"><strong>Background:</strong> Tuberculosis and HIV co-infection remains a major public health challenge throughout the world. An extra 25% of deaths among TB patients are attributable to co-infection with HIV according to the WHO 2009 TB report. TB is often the first opportunistic infection and a leading cause of death in HIV infected persons. The main objective was to study the clinical profile of the patients co-infected with HIV and abdominal tuberculosis in Government Medical College, Aurangabad.</p><p class="abstract"><strong>Methods:

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Mauskar, Anupama Vinayak, and Amrit Gopan. "Clinical profile of pulmonary tuberculosis and MDR TB in children at tertiary medical institute." International Journal of Contemporary Pediatrics 6, no. 6 (2019): 2571. http://dx.doi.org/10.18203/2349-3291.ijcp20194736.

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Background: India is the country with highest burden of TB. There is paucity of data as far as Pediatric TB is concern. TB in children directly reflects intensity of on-going transmission of TB in a given community. This study was done including indoor cases of Pediatric pulmonary TB in a medical college hospital, a tertiary care institute in the city of Mumbai. The aim and objectives of this study the clinical profile and outcome of Pediatric pulmonary tuberculosis/MDR TB in an indoor setting of a tertiary care center. It was a clinical observational study in a setting of medical college hosp

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Triya Malde, Gaurang Pabani, and O.P. Shukla. "Study of Clinico-Radiological Profile in Childhood Tuberculosis." Asian Journal of Clinical Pediatrics and Neonatology 8, no. 1 (2020): 09–14. http://dx.doi.org/10.47009/ajcpn.2020.8.1.3.

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Background: Tuberculosis still is one of the deadliest diseases in the world killing nearly 2 million people every year. In India, two deaths occur every three minutes from tuberculosis. The actual global disease burden of childhood tuberculosis is not known, as childhood Tuberculosis is notoriously difficult to diagnose because of the absence of a ‘gold standard’ as bacteriologic confirmation is rarely achieved. The present study was designed to study clinical profile of various forms of childhood TB. Objective of this study was to study clinic-epidemiological profile of various forms of chil

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Narasimhamurthy, Diwakar Tumkur, David Mathew Thomas, Ravi Krishnegowda, et al. "Clinical profile and outcome of HIV-TB Co‑Infection at a centre of excellence for HIV care." Asian Journal of Medical Sciences 9, no. 2 (2018): 19–24. http://dx.doi.org/10.3126/ajms.v9i2.17261.

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Background: Tuberculosis (TB) and Human Imuunodeficiency Virus (HIV) co-infection has detrimental effects on both the individual and the health care system especially in resource limited countries like India. Tuberculosis ranks among the most common cause of death in HIV patients. In this review we have analysed the clinical and immunological characteristicsof HIV-TB coinfected patients and their clinical outcomes.Aims and Objectives: To assess the co-relation between socio-demographic characteristics, clinical and immunological Profile of HIV-TB co-infected patients and the clinical outcome.M

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Teixeira, Francine, Sonia M. Raboni, Clea EL Ribeiro, João CB França, Anne C. Broska, and Nathalia LS Souza. "Human Immunodeficiency Virus and Tuberculosis Coinfection in a Tertiary Hospital in Southern Brazil: Clinical Profile and Outcomes." Microbiology Insights 11 (January 2018): 117863611881336. http://dx.doi.org/10.1177/1178636118813367.

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Worldwide, the convergence of tuberculosis (TB) and human immunodeficiency virus type 1 (HIV-1) infection epidemics is a public health challenge. In Brazil, TB is the leading cause of death by infectious disease in people living with HIV (PLWH). This study aimed to report the clinical, demographic, epidemiological, and laboratory data for TB in PLWH. This cross-sectional study involved a retrospective analysis of data for patients with TB/HIV coinfection who attended from 2006 to 2015 through a review of medical records. A total of 182 patients were identified, of whom 12 were excluded. Patien

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Kawatsu, Lisa, Kazuhiro Uchimura, Makoto Kobayashi, and Nobukatsu Ishikawa. "The profile of prisoners with tuberculosis in Japan." International Journal of Prisoner Health 14, no. 3 (2018): 153–62. http://dx.doi.org/10.1108/ijph-03-2017-0013.

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Purpose Although globally, prisoners are considered one of the vulnerable groups to tuberculosis (TB), little is known about the situation of TB in prison setting in Japan. The purpose of this paper is to examine the characteristics of TB among prisoners in Japan. Design/methodology/approach Records of TB patients from one medical prison were analyzed in terms of general demographic characteristics, clinical manifestations, risk factors and delay in diagnosis and in initiating treatment, and compared with data from the national TB surveillance and other published data on health of inmates, whe

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Adiwinata, Randy, Josephine Rasidi, and Maurits Marpaung. "Clinical Profile and Treatment Evaluation of Rifampicin-Resistant and Multidrug-Resistant Tuberculosis Patients at Dr. Kanujoso Djatiwibowo Public Hospital, Balikpapan." Jurnal Respirologi Indonesia 38, no. 3 (2018): 135–42. http://dx.doi.org/10.36497/jri.v38i3.2.

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Background: Rifampicin-resistant (RR-TB) and multidrug-resistant tuberculosis (MDR-TB) remains a major health problem worldwide and in Indonesia also become a challenge in total eradication of tuberculosis. Dr. Kanujoso Djatiwibowo Public Hospital (RSKD) Balikpapan is one of the two referral hospitals in East Kalimantan for evaluation and initiation of MDR-TB treatment. The objective of this study is to evaluate clinical profile and treatment of RR-TB and MDR-TB patients at RSKD. Methods: A retrospective cross-sectional study was conducted using data from eTB manager da

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Rymanova, I., M. Nosik, S. Sevostyanihin, and A. Sobkin. "Socio-demographic and clinical profile of TB/HIV-co-infected patients." International Journal of Infectious Diseases 53 (December 2016): 86. http://dx.doi.org/10.1016/j.ijid.2016.11.217.

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Kaawan, Amani. "MMED PROJECT The Clinical Profile of Takayasu Disease at Tygerberg Academic Hospital – a retrospective study." Clinical Cardiology and Cardiovascular Interventions 3, no. 11 (2020): 01–12. http://dx.doi.org/10.31579/2641-0419/103.

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Takayasu’s arteritis (TA) is a disease of unknown etiology that causes chronic inflammation of the large blood vessels and usually involves the aorta and its branches. The inflammatory process initially leads to thickening of the arterial wall and may result in stenosis, occlusion, dilatation or aneurysm formation. Although TA occurs more commonly in certain regions such as Asia, it is a global disease. Currently, there is a dearth of information on this condition in African countries, including South Africa. Results: We have identified 50 patients meeting the ACR criteria for the diagnosis of

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Damayanti, Meisika, and Surati Surati. "Profile of SGPT Levels in Multidrug Resistant Tuberculosis Patients (MDR-TB)." Jaringan Laboratorium Medis 2, no. 2 (2021): 68–74. http://dx.doi.org/10.31983/jlm.v2i2.7687.

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Multidrug Resistant Tuberculosis (MDR-TB) has recently become a health threat in Indonesia. The clinical management of MDR TB is more complicated than that of ordinary TB. Hepatotoxicity or commonly known as Anti-Tuberculosis Drug-induced Hepatotoxicity (ATDH) is a serious effect of OAT that often occurs. The basic parameter for diagnosing or following up the presence of impaired liver function is the SGPT examination. The purpose of this study was to describe the level of SGPT in MDR-TB patients at the Kendal District Health Center. This study is an observational (non-experimental) study with

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Shafiq, Syed. "Clinical, Imaging, and Endoscopic Profile of Patients with Abdominal Tuberculosis." Journal of Digestive Endoscopy 10, no. 02 (2019): 112–17. http://dx.doi.org/10.1055/s-0039-1693272.

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Abstract Aims: The aim is to study the clinical, imaging, and endoscopic profile of patients with abdominal tuberculosis (TB) in a tertiary care center. Subjects and Methods: This was a prospective observational study conducted at Meenakshi Medical College Hospital, Kancheepuram, over a 3-year period, from March 2011 to February 2014. A total of 76 patients were diagnosed with abdominal TB based on their clinical, pathological, endoscopic, and radiological features. A meticulous history and physical examination with complete blood count, human immunodeficiency virus (HIV) status, chest X-ray,

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Mortel, Maika Kamille, Ana Patricia Alcasabas, and Anna Lisa Ong-Lim. "#95: Clinical Profile and Outcome of Pediatric Acute Lymphoblastic Leukemia Patients with Tuberculosis at the Philippine General Hospital." Journal of the Pediatric Infectious Diseases Society 10, Supplement_1 (2021): S17. http://dx.doi.org/10.1093/jpids/piaa170.054.

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Abstract Background The Philippines remains one of the countries on the WHO list of high-burden countries for tuberculosis (TB), and malignancy has long been recognized as a risk factor for this disease. This report describes the clinical profile and outcomes of pediatric patients with acute lymphoblastic leukemia (ALL) diagnosed with tuberculosis. Methods Medical records of pediatric patients with ALL consulting at the University of the Philippines – Philippines General Hospital diagnosed from January 2015 to December 2017 (excluding those with concomitant HIV infection) were reviewed. Those

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Agrahari, Saurabh, Maneshwar Singh Utaal, and Sharadendu Bali. "Clinical profile of patients with abdominal tuberculosis in rural North India." International Surgery Journal 6, no. 3 (2019): 836. http://dx.doi.org/10.18203/2349-2902.isj20190477.

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Background: Tuberculosis is a very serious health hazard in India. The nonspecific clinical features of abdominal tuberculosis (TB) have made its diagnosis difficult, which can lead to the poor outcome in patients who are not able to receive early treatment especially from rural areas. Aim of our study was to determine the clinical profile including various clinico-pathological manifestations, demographic profile, spectrum of clinical presentation, etiology, pathological and radiological investigations of patients with abdominal TB.Methods: A total of 30 patients with abdominal TB were analyse

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Wani, Abdul Ahad, Javeed Iqbal Bhat, Muzafar Naik, Nisar Ahmed Dar, and Syed Masood Ahmed. "Sociodemographic, Clinical Profile and Outcome of Tuberculosis in Baramulla District of North Kashmir of India." JMS SKIMS 21, no. 1 (2018): 11–16. http://dx.doi.org/10.33883/jms.v21i1.336.

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Background: India accounts for one-fourth of the global tuberculosis (TB) burden. Since the countrywide implementation of RNTCP, tuberculosis care has received renewed focus. Directly observed treatment short-term (DOTS) is a cornerstone of RNTCP program. Objective: To evaluate demographic profile, clinical presentation and outcome of TB in district Baramulla of North Kashmir. Methods: A prospective study over a period of seven years in patients diagnosed with TB in district Baramulla of North Kashmir. Results: This study was conducted prospectively over seven years from Marc

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Awasthi, Sadhana, Neha Verma, Ram Gopal Nautiyal, and Hariom Kumar Solanki. "Profile of Multi Drug Resistant Tuberculosis patients: A Study at Drug Resistant Tuberculosis Centre in Kumaun Region, Uttarakhand." Indian Journal of Community Health 32, no. 4 (2020): 647–52. http://dx.doi.org/10.47203/ijch.2020.v32i04.007.

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Background: Drug Resistant Tuberculosis (DR-TB) has frequently been encountered in India, and its presence has been known virtually from the time anti-TB drugs were introduced for the treatment of Tuberculosis. Multi Drug Resistant Tuberculosis (MDR-TB) is a man-made phenomenon and has become a formidable challenge to effective Tuberculosis control in India. Objectives: To study the Socio-demographic and Clinical profile of Multi Drug Resistant Tuberculosis (MDR-TB) patients presenting to Drug Resistant Tuberculosis (DR-TB) Centre at Govt. Medical College, Haldwani in the Kumaun region, Uttara

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Kumar, Ashna, Javid Ahmad, Pooja Bharti, and Vasundhara Bakshi. "Clinical profile of pediatric patients with tuberculosis in a tertiary care centre in India." International Journal of Contemporary Pediatrics 7, no. 9 (2020): 1906. http://dx.doi.org/10.18203/2349-3291.ijcp20203653.

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Background: India has one of the highest TB burden globally. Children contribute a significant proportion of TB burden, in whom the diagnosis can be challenging because many childhood diseases mimic TB. Therefore, a high index of suspicion is required for early diagnosis of childhood tuberculosis to prevent poor outcome. Objectives was to evaluate the prevalence and profile of childhood tuberculosis cases and to determine the risk factorsMethods: An observational cross-sectional study was conducted over a period of 6 months at a hospital in north India and the prevalence and profile of the chi

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Singh, Krishna K., Yuxin Dong, John T. Belisle, Jeffrey Harder, Vijay K. Arora, and Suman Laal. "Antigens of Mycobacterium tuberculosis Recognized by Antibodies during Incipient, Subclinical Tuberculosis." Clinical Diagnostic Laboratory Immunology 12, no. 2 (2005): 354–58. http://dx.doi.org/10.1128/cdli.12.2.354-358.2005.

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ABSTRACT Serum samples obtained from human immunodeficiency virus (HIV)-infected tuberculosis (TB) patients months prior to clinical TB were used to delineate the profile of Mycobacterium tuberculosis culture filtrate proteins recognized during subclinical TB. A subset of ∼12 antigens was recognized by antibodies in these serum samples. Antibodies to two of these antigens (81 [88]-kDa malate synthase [GlcB] and MPT51) were present in serum samples obtained during incipient subclinical TB in 19 (∼90%) of the 21 HIV-infected TB patients tested. These antigens will be useful for devising diagnost

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Landsman, David, Ahmed Abdelbasit, Christine Wang, et al. "Cohort profile: St. Michael’s Hospital Tuberculosis Database (SMH-TB), a retrospective cohort of electronic health record data and variables extracted using natural language processing." PLOS ONE 16, no. 3 (2021): e0247872. http://dx.doi.org/10.1371/journal.pone.0247872.

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Background Tuberculosis (TB) is a major cause of death worldwide. TB research draws heavily on clinical cohorts which can be generated using electronic health records (EHR), but granular information extracted from unstructured EHR data is limited. The St. Michael’s Hospital TB database (SMH-TB) was established to address gaps in EHR-derived TB clinical cohorts and provide researchers and clinicians with detailed, granular data related to TB management and treatment. Methods We collected and validated multiple layers of EHR data from the TB outpatient clinic at St. Michael’s Hospital, Toronto,

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Bastos, Shyrlaine Honda, Mônica Taminato, Hugo Fernandes, Tânia Maria Ribeiro Monteiro de Figueiredo, Lúcia Yasuko Izumi Nichiata, and Paula Hino. "Sociodemographic and health profile of TB/HIV co-infection in Brazil: a systematic review." Revista Brasileira de Enfermagem 72, no. 5 (2019): 1389–96. http://dx.doi.org/10.1590/0034-7167-2018-0285.

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ABSTRACT Objective: to ascertain the epidemiological profile of TB/HIV co-infection in Brazilian scenarios. Method: this is a systematic review conducted via electronic search in databases PubMed, EMBASE, LILACS and SciELO, having as inclusion criterion articles based on the Brazilian scenario of TB/HIV co-infection. Results: of the total 174 studies, 15 were selected, revealing the epidemiological profile of the co-infection in different scenarios: male, economically active age, low education level, brown/black ethnicity, low income, heterosexual, pulmonary clinical form, alcoholism and Direc

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Khan, Aminuddin A., Md Zahangir Alam Chowdhury, Mohammad Moin Uddin, Nusrat Sultana, and Ahsanul Hoque Chowdhury. "Clinical Profile of Indoor Patients in the Department of Physical Medicine and Rehabilitation, Chittagong Medical College Hospital." Chattagram Maa-O-Shishu Hospital Medical College Journal 13, no. 1 (2014): 36–38. http://dx.doi.org/10.3329/cmoshmcj.v13i1.19416.

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Background: This observational study done on the indoor patients of department of Physical Medicine and Rehabilitation, Chittagong Medical College Hospital, admitted during the year 2011. The objective of this study was to see the most prevalent diseases admitted in our department.Methods: Participants (225) were all the patients admitted during the period of 2011. Patients admitted more than once were recorded once only. Patients data were taken from hospital records.Results: Spondyloarthropathies (SpA) comprised 18.66% of the patients. Total patient of SpA was 42. Among them AS was 47.62%.

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Tenali, Ravikumar, Naveen Kumar Badri, Jithendra Kandati, and Munilakshmi Ponugoti. "Risk factors, clinico-epidemiological profile of tuberculosis among children attending a tertiary care hospital: a two year study." International Journal of Contemporary Pediatrics 5, no. 3 (2018): 851. http://dx.doi.org/10.18203/2349-3291.ijcp20181501.

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Background: TB remains as the one among the top 10 causes of death worldwide. In 2016, 10.4 million people fell ill with TB, and 1.7 million died from the disease with 0.4 million with HIV. At least 1 million children become ill with TB each year. Children represent about 10-11% of all TB cases. Having knowledge of the risk factors for tuberculosis infection in children is important to evaluate the level of ongoing transmission of infection and to help adapt activities within national TB control programs. The main objective is to study the risk factors and their association and variable clinic

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Khan, Imran H., Resmi Ravindran, Viswanathan V. Krishnan, et al. "Plasma Antibody Profiles as Diagnostic Biomarkers for Tuberculosis." Clinical and Vaccine Immunology 18, no. 12 (2011): 2148–53. http://dx.doi.org/10.1128/cvi.05304-11.

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ABSTRACTTwo billion people are infected withMycobacterium tuberculosis, the etiological agent of tuberculosis (TB), worldwide. Ten million to 20 million of the infected individuals develop disease per year. TB is a treatable disease, provided that it is diagnosed in a timely manner. The current TB diagnostic methods are subjective, inefficient, or not cost-effective. Antibody-based blood tests can be used efficiently and cost-effectively for TB diagnosis. A major challenge is that different TB patients generate antibodies against different antigens. Therefore, a multiplex immunoassay approach

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Uike, Pravin, Prabhakar Hiwarkar, Vilas Malkar, and Ketan Aswalle. "Profile of multi drug resistant (MDR) and rifampicin resistant TB patients treated under category IV of RNTCP." International Journal of Basic & Clinical Pharmacology 6, no. 4 (2017): 784. http://dx.doi.org/10.18203/2319-2003.ijbcp20170992.

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Background: The emergence of resistance to drugs used to treat tuberculosis (TB) and particularly multidrug resistance TB (MDR-TB) has become a significant health problem and obstacle to effective TB control in India. Present study was conducted to study clinical and sociodemograohic profile of MDR and rifampicin resistant TB patients registered for treatment under RNTCP in Yavatmal district of Maharashtra state.Methods: All drug resistant (MDR and rifampicin resistant) TB patients residents of Yavatmal district, treated at DOTS plus site with Standardized Treatment Regimen (STR) from 1st quar

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Gautam, Pooja, Neelima Sharma, Bishal Gautam, Preksha Sharma, and Neha Sharma. "Clinical profile of tuberculosis with diabetes mellitus." International Journal of Research in Medical Sciences 9, no. 6 (2021): 1692. http://dx.doi.org/10.18203/2320-6012.ijrms20212237.

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Background: There is now good evidence that people with diabetes mellitus (DM) have 2–3 times the risk of developing active tuberculosis (TB) compared with those who do not have DM. The aim of the study was to analyze typical / atypical presentation of pulmonary tuberculosis with diabetes mellitus.Methods: This study was carried out in the Department of Respiratory Medicine and General Medicine, SAIMS, Indore during the period of July 2012 to June 2014. A prospective study including 100 microscopically proven cases of sputum smear positive pulmonary tuberculosis. Among these, 50 are diabetic p

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., Shilpa, and Aakash Andgi. "Clinical profile of opportunistic infections in HIV seropositive patients attending tertiary centre, Raichur, India." International Journal of Advances in Medicine 5, no. 6 (2018): 1369. http://dx.doi.org/10.18203/2349-3933.ijam20184738.

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Background: According to Karnataka state HIV statistics, HIV positivity among general clients tested at ICTCs, Raichur (4.9%) had third highest proportion of HIV positive cases. Authors decided to focus on opportunistic infections (OIs) in HIV patients of Raichur district since they contribute to the mortality and morbidity.Methods: It’s a cross sectional, hospital-based study with 100 patients with HIV infections as per NACO guidelines with features of OIs were included in study.Results: In this study, 77 males (77%), 23 female (23%) patients with 58% (n=58) of them in 30-39yrs age group and

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OSHI, S. N., I. ALOBU, K. N. UKWAJA, and D. C. OSHI. "Investigating gender disparities in the profile and treatment outcomes of tuberculosis in Ebonyi state, Nigeria." Epidemiology and Infection 143, no. 5 (2014): 932–42. http://dx.doi.org/10.1017/s095026881400291x.

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SUMMARYGlobally, twice as many men as women are being diagnosed with tuberculosis (TB) annually. Little is known about gender differentials in TB in Africa. A retrospective cohort analysis of routine data was conducted on adult TB patients treated between 2011 and 2012 in two large healthcare facilities in Nigeria. Gender differences in their demographic characteristics and treatment outcomes were analysed accordingly. Of 1668 TB patients enrolled, the male:female ratio was 1·4:1. The mean ages of males and females were 40·2 ± 14·7 and 36·1 ± 14·6 years, respectively (t test 6·62, P < 0·001

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Nzombe, Phoebe, Srinath Satyanarayana, Hannock Tweya, et al. "Declining Trends in Childhood TB Notifications and Profile of Notified Patients in the City of Harare, Zimbabwe, from 2009 to 2018." Journal of Tropical Medicine 2020 (May 21, 2020): 1–8. http://dx.doi.org/10.1155/2020/4761051.

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Globally, childhood tuberculosis (TB among those aged <15 years) is a neglected component of national TB programmes in high TB burden countries. Zimbabwe, a country in southern Africa, is a high burden country for TB, TB-HIV, and drug-resistant TB. In this study, we assessed trends in annual childhood TB notifications in Harare (the capital of Zimbabwe) from 2009 to 2018 and the demographic, clinical profiles, and treatment outcomes of childhood TB patients notified from 2015–2017 by reviewing the national TB programme records and reports. Overall, there was a decline in the total number of

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Chaudhary, Aswani, DP Sarraf, NR Bhattarai, A. Chaudhary, and GP Rauniar. "Clinical Profile, Drug Utilization Pattern and Adverse Drug Reactions of Anti-tubercular Drugs at DOTS Center in a Tertiary Hospital." Nepal Medical College Journal 22, no. 3 (2020): 158–66. http://dx.doi.org/10.3126/nmcj.v22i3.32650.

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Most of anti-tubercular drugs (ATD) cause various adverse drug reactions (ADRs) leading to significant morbidity which may have negative consequences on drug adherence and treatment outcome. The objectives of the study were to know the clinical profile of patients receiving ATD, to identify the pattern of ADRs caused by ATD and to know the drug utilization pattern (DUP) in different types of tuberculosis (TB). A prospective observational study was conducted among patients diagnosed with TB at DOTS center in BPKIHS from June 2017 to May 2018 and occurrence of any ADRs were detected during their

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G., Anuradha, and Muraleetharan G. "Clinical profile of children with tuberculosis from a semi urban referral centre in South India: a prospective observational study." International Journal of Contemporary Pediatrics 6, no. 4 (2019): 1450. http://dx.doi.org/10.18203/2349-3291.ijcp20192127.

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Background: Global TB report 2018 reports that in India, an estimated 2.2 lakh children become ill with tuberculosis (TB) each year. In spite of new rapid diagnostic methods, lack of gold standard test for confirming childhood tuberculosis remains an obstacle for the effective reporting of childhood TB and hence these cases often remain under diagnosed. The main objective was to study the clinical profile of childhood tuberculosis with relevant laboratory investigations aiding in early diagnosis.Methods: A prospective observational hospital-based study was conducted in IRT-Perundurai medical c

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Hossain, Nazia, Kamruzzaman Kamrul, Akhand Tanzih Sultana, Md Shakibur Rahman, and Md Ruhul Amin. "Recurrent and Persistent Pneumonia in Dhaka Shishu (Children) Hospital: Clinical Profile and Etiology." Bangladesh Journal of Child Health 42, no. 3 (2018): 125–29. http://dx.doi.org/10.3329/bjch.v42i3.39261.

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Background: Recurrent and persistent pneumonia have become a challenge for the physicians. The aim of this study was to evaluate the clinical profile and determine the underlying causes of recurrent and persistent pneumonia among the children admitted in Dhaka Shishu (Children) Hospital. Methods: In this study, retrospective analysis of medical records of the children was done, who met the criteria of recurrent pneumonia and persistent pneumonia. Analyzed Patients were admitted in Dhaka Shishu (Children) Hospital from January 2016 to Decembe 2016. Results: A total of 30 patients we

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Bardou, Maine L. D., Sandra Ervolino, Iran S. P. Martins Filho, Hyun M. Yang, and Saulo D. Passos. "The tuberculosis recurrence in city of Jundiaí since 2006 to 2011: a clinical and epidemiological profile." Medicina (Ribeirao Preto. Online) 49, no. 3 (2016): 258. http://dx.doi.org/10.11606/issn.2176-7262.v49i3p258-264.

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A recidiva de Tuberculose (TB) ocorre quando um paciente apresenta diagnóstico atual de Tuberculose, bacteriologicamente positiva (microscopia ou cultura), com história de TB anterior curada com medicamentos anti-TB. Avaliar os aspectos clínicos e epidemiológicos da recidiva de Tuberculose é de extrema importância, pois este dado é capaz de nortear e esclarecer a eficiência do Directly Observed Treatment Short (DOTS), o esquema terapêutico utilizado e as características dos pacientes com recidiva. Objetivo: Descrever algumas características do perfil clínico e epidemiológico de casos de recidi

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Pramegia, Desak Ketut Nari Swari, Rio Putratama Achmad Faried, Kelvin Setiawan, Bramastha Aires Rosadi, and Terry Renata Lawanto. "Demographic and Clinical Profile of Tuberculous Mastitis Patients at Tebet General Hospital, Jakarta." JBN (Jurnal Bedah Nasional) 3, no. 2 (2019): 32. http://dx.doi.org/10.24843/jbn.2019.v03.i02.p01.

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Aim: Objective of the study is to find out the demographic and clinical profile of tuberculous mastitis (TM) patients. Methods: The study was carried out for a period of one year from August 2017 to August 2018 at Tebet General Hospital. Histopathologically diagnosed cases of TM were retrospectively studied. Results: All eight patients diagnosed as suffering from TM were females with the mean age of 37.25 years. Of these, two patients were lactating, six others were not, and 75% were multiparous. Unilateral involvement was observed in all cases. The right breast was affected in 62.5% and left

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Kik, Sandra V., Samuel Schumacher, Daniela Maria Cirillo, et al. "An evaluation framework for new tests that predict progression from tuberculosis infection to clinical disease." European Respiratory Journal 52, no. 4 (2018): 1800946. http://dx.doi.org/10.1183/13993003.00946-2018.

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Novel accurate tests are needed that identify individuals infected with Mycobacterium tuberculosis who have incipient disease and are likely to develop clinical tuberculosis (TB) in the near future to allow for targeted preventive treatment beyond the current risk groups. Recently, a target product profile was developed that outlines the minimal and optimal characteristics for such an incipient TB test. We describe an evaluation framework for generating evidence to inform the development of policy guidance for the use of such a new test by the World Health Organization. Two research objectives

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Lamb, Avinash R., Hrishikesh A. Khadilkar, and Syed Azhar Ali Shoukat Ali. "Clinical profile and treatment outcome of tuberculosis patients under programmatic management in a tuberculosis unit at a tertiary care center." International Journal Of Community Medicine And Public Health 5, no. 7 (2018): 2825. http://dx.doi.org/10.18203/2394-6040.ijcmph20182521.

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Background: Tuberculosis (TB) is currently one of the greatest health hazards in the world, more so in India. So this study was conducted to study the clinical profile and treatment outcome of TB patients in a tuberculosis unit attached to a tertiary care centre.Methods: A retrospective study was conducted among the tuberculosis patients attending the tuberculosis unit attached to Government Medical College, Aurangabad, Maharashtra. In which patient’s clinico-demographic profile and treatment outcome was recorded.Results: A total of 2414 patients were included in this study of which 1377 (57.0

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Jemaa, Maissa Ben, Makram Koubaa, Houda Ben Ayed, et al. "768. Epidemiological and Clinical Profile of Miliary Tuberculosis in Southern of Tunisia." Open Forum Infectious Diseases 5, suppl_1 (2018): S275—S276. http://dx.doi.org/10.1093/ofid/ofy210.775.

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Abstract Background Miliary tuberculosis (MT) is a severe rare form of tuberculosis (TB). It is often due to lymphohaematogenous dissemination of tubercle bacilli. Although the global incidence of TB has been slowly decreasing with globally conducted program, MT incidence is relatively increasing owing mainly to widespread use of immunosuppressive drugs and HIV/AIDS pandemicity. Few reports were found regarding epidemiological data of MT in developing countries. We aim to evaluate epidemiological characteristics of MT in the region of Sfax Southern Tunisia. Methods We conducted a retrospective

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Liang, Tuo, Jiarui Chen, GuoYong Xu, et al. "Immune status changing helps diagnose osteoarticular tuberculosis." PLOS ONE 16, no. 6 (2021): e0252875. http://dx.doi.org/10.1371/journal.pone.0252875.

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Objective This study is aimed to develop a new nomogram for the clinical diagnosis of osteoarticular tuberculosis (TB). Methods xCell score estimation to obtained the immune cell type abundance scores. We downloaded the expression profile of GSE83456 from GEO and proceed xCell score estimation. The routine blood examinations of 326 patients were collected for further validation. We analyzed univariate and multivariate logistic regression to identified independent predicted factor for developing the nomogram. The performance of the nomogram was assessed using the receiver operating characterist

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Dahiya, Neha, D. Bachani, R. Das, and SK Rasania. "SOCIO-DEMOGRAPHIC AND CLINICAL PROFILE OF HIV POSITIVE PATIENTS ATTENDING INTEGRATED COUNSELING & TESTING CENTRE OF A PRIMARY HEALTH CENTRE IN DELHI." SAARC Journal of Tuberculosis, Lung Diseases and HIV/AIDS 14, no. 1 (2017): 22–26. http://dx.doi.org/10.3126/saarctb.v14i1.17725.

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Introduction: The Human Immunodeficiency Virus (HIV) infection is a global pandemic affecting principally the sexually active and economically productive population of any country. Additionally the dual epidemic of HIV and TB infection is of growing concern in Asia, where nearly two-third of TB-infected individuals live and where tuberculosis now accounts for 40 percent of HIV/AIDS deaths. Keeping this in mind, a study was conducted to understand the profile of HIV/AIDS patients attending Integrated Counseling and Testing Center (ICTC) located at Primary Health Centre, Palam in Delhi.Methodolo

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Colman, Rebecca E., Julia Anderson, Darrin Lemmer, et al. "Rapid Drug Susceptibility Testing of Drug-Resistant Mycobacterium tuberculosis Isolates Directly from Clinical Samples by Use of Amplicon Sequencing: a Proof-of-Concept Study." Journal of Clinical Microbiology 54, no. 8 (2016): 2058–67. http://dx.doi.org/10.1128/jcm.00535-16.

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Increasingly complex drug-resistant tuberculosis (DR-TB) is a major global health concern and one of the primary reasons why TB is now the leading infectious cause of death worldwide. Rapid characterization of a DR-TB patient's complete drug resistance profile would facilitate individualized treatment in place of empirical treatment, improve treatment outcomes, prevent amplification of resistance, and reduce the transmission of DR-TB. The use of targeted next-generation sequencing (NGS) to obtain drug resistance profiles directly from patient sputum samples has the potential to enable comprehe

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Dam, T., M. Isa, and M. Bose. "Drug-sensitivity profile of clinical Mycobacterium tuberculosis isolates – a retrospective study from a chest-disease institute in India." Journal of Medical Microbiology 54, no. 3 (2005): 269–71. http://dx.doi.org/10.1099/jmm.0.45635-0.

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Multi-drug-resistant tuberculosis (MDR-TB) is a major public-health problem, because treatment is complicated and patients remain infectious for months or years, despite receiving the best available therapy. To gain better understanding of MDR-TB, a retrospective study was initiated to determine the level of drug resistance among patients in a chest-disease institute in India. Two hundred and sixty-three isolates from treatment-failure pulmonary tuberculosis patients (20–70 years) were studied. Drug-sensitivity testing was performed by the modified-proportion method. First- and second-line dru

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Fontalvo-Rivera, Dilia, Enrique Mazenett, Luisana Cárcamo-Marrugo, Claudia Llerena-Polo, and Doris Gómez-Camargo. "Tuberculosis in Immigrants to Cartagena de Indias, Colombia." International Journal of Travel Medicine and Global Health 8, no. 3 (2020): 100–106. http://dx.doi.org/10.34172/ijtmgh.2020.18.

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Introduction: Tuberculosis (TB) affects vulnerable populations. Immigrants have contributed to the increased incidence of TB. In this population, TB has some common characteristics that can lead to increased resistance to anti-TB drugs and undesired outcomes. In Cartagena de Indias, Colombia, an increase in TB cases has been observed in immigrants. Our objective is to describe the clinical and microbiological characteristics of Mycobacterium tuberculosis in the immigrant population of Cartagena de Indias, Colombia. Methods: A descriptive study of 101 patients with a clinical and microbiologica

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Bohara, Madan Singh. "Pulmonary tuberculosis and immunological profile of HIV/AIDS patients in Far West Nepal." Journal of Kathmandu Medical College 3, no. 1 (2014): 8–13. http://dx.doi.org/10.3126/jkmc.v3i1.10917.

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Background: Tuberculosis is itself a major public health problem in Nepal and the emergence HIV further complicated the issue. Tuberculosis is the most common cause of death among HIV/AIDS patients worldwide. Tuberculosis and HIV co-infection is associated with special diagnostic and ther apeutic challenges and constitutes an immense burden on healthcare system of heavily infected countries like Nepal. Objective: The objective of the study was to determine the prevalence of pulmonary tuberculosis and their immunologic profi les among HIV positive patients. Methods: A hospital based cross-secti

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Bariha, P. K., U. P. Pujari, B. K. Kullu, and A. Thakur. "Prospective study of tubercular co-infection in HIV infected patients in VIMSAR, Burla, Sambalpur, Odisha, India." International Journal of Advances in Medicine 5, no. 3 (2018): 530. http://dx.doi.org/10.18203/2349-3933.ijam20181979.

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Background: Tuberculosis is the most common opportunistic infection in HIV positive patient. This is a major challenge faced by HIV positive patient. Methods: This study was carried out at Medicine Department and ART Centre, VIMSAR, Burla to know the epidemiology and clinical profile of HIV and TB co-infection. This is a prospective study in which all adult patients attending to our hospital for period of one year with HIV-TB co infection are enrolled. There were 269 patients. The clinical parameters are studied after all detailed history and clinical examination. The diagnosis of Tuberculosis

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Nerurkar, Rajeev, and Shraddha Singh. "Tubercular Laryngitis: A Rebirth?" International Journal of Phonosurgery & Laryngology 6, no. 1 (2016): 17–19. http://dx.doi.org/10.5005/jp-journals-10023-1113.

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ABSTRACT Objective The aim of this study is to highlight the changing clinical patterns of laryngeal tuberculosis (TB) and to increase the awareness of this uncommon manifestation of extrapulmonary TB which will help the clinician in early diagnosis and appropriate management of this condition. Materials and methods A retrospective analysis was done of 34 suspected cases of tubercular laryngitis who presented to our institution from January 2009 to December 2011. All of these patients were subjected to hematological tests, sputum microscopy, and radiological investigations. Results Out of thes

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Samanich, K. M., M. A. Keen, V. D. Vissa, et al. "Serodiagnostic Potential of Culture Filtrate Antigens of Mycobacterium tuberculosis." Clinical Diagnostic Laboratory Immunology 7, no. 4 (2000): 662–68. http://dx.doi.org/10.1128/cdli.7.4.662-668.2000.

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ABSTRACT Our studies of the humoral responses of tuberculosis (TB) patients have defined the repertoire of culture filtrate antigens ofMycobacterium tuberculosis that are recognized by antibodies from cavitary and noncavitary TB patients and demonstrated that the profile of antigens recognized changes with disease progression (K. Samanich et al., J. Infect. Dis. 178:1534–1538, 1998). We have identified several antigens with strong serodiagnostic potential. In the present study we have evaluated the reactivity of cohorts of human immunodeficiency virus (HIV)-negative, smear-positive; HIV-negati

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Nigam, Abhishek, and Prakash Joshi. "CLINICAL AND RADIOLOGICAL STUDY OF PULMONARY TUBERCULOSIS IN DIABETES MELLITUS." International Journal of Advanced Research 9, no. 06 (2021): 09–14. http://dx.doi.org/10.21474/ijar01/12983.

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Background: Tuberculosis is the third most important communicable disease in Egypt follows the schistosomiasis. The association between TB and DM has been known for thousands of years, Although the incidence of TB is declining slowly, the burden of diabetes is increasing very rapidly, many studies have been performed to answer about the effect of type 2 DM in clinical, radiological and the outcome of pulmonary tuberculosis, however there is still a huge gap of knowledge about the synergetic effect of the two diseases. The objective was to study the clinical and radiological profile of pulmonar

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Loh, Sin Wee, Koh Cheng Thoon, Natalie Woon Hui Tan, Jiahui Li, and Chia Yin Chong. "Paediatric tuberculosis in Singapore: a retrospective review." BMJ Paediatrics Open 2, no. 1 (2018): e000308. http://dx.doi.org/10.1136/bmjpo-2018-000308.

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BackgroundTuberculosis (TB) is a major cause of mortality and morbidity in the world. Each case represents ongoing transmission and has a significant public health burden. We aim to examine the clinical profile of paediatric TB and compare pulmonary TB (PTB) with extrapulmonary TB (EPTB) in Singapore.MethodsA retrospective study of patients admitted to KK Women’s and Children’s Hospital, Singapore from January 2008 to September 2017 with active TB was undertaken. The clinical characteristics and outcomes of patients with PTB and EPTB were compared.ResultsSeventy-five patients were diagnosed as

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B. Bilagi, Rakesh, and Hafiz Deshmukh. "Study of clinical profile of tuberculosis patients admitted in respiratory medicine ward at a tertiary care hospital in Marathwada." International Journal of Advances in Medicine 5, no. 1 (2018): 68. http://dx.doi.org/10.18203/2349-3933.ijam20180003.

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Background: Tuberculosis is one of the most important cause of most of the respiratory diseases. It is estimated that about one-third of the world's population is infected with mycobacterium tuberculosis. It is important to know about the clinical profile of these patients. There are many studies which are done among OPD patients but fewer among indoor patients hence, the current study was planned.Methods: Retrospective study of the patients admitted in the inpatient department of the study area were taken as the sample size from May 2016 to April 2017, who were diagnosed as TB patients.Result

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Evangelatos, Gerasimos, Vasiliki Koulouri, Alexios Iliopoulos, and George E. Fragoulis. "Tuberculosis and targeted synthetic or biologic DMARDs, beyond tumor necrosis factor inhibitors." Therapeutic Advances in Musculoskeletal Disease 12 (January 2020): 1759720X2093011. http://dx.doi.org/10.1177/1759720x20930116.

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Patients with autoimmune rheumatic diseases (ARD) have an increased risk for tuberculosis (TB). The use of tumor necrosis factor inhibitors (TNFi) and glucocorticoids in these patients has been associated with an increased prevalence of latent TB reactivation. Over the last few years, several biologic disease-modifying anti-rheumatic drugs (bDMARDs), other than TNFi (e.g. rituximab, abatacept, tocilizumab, secukinumab) and targeted synthetic DMARDs (tsDMARDs) [e.g. apremilast, Janus kinase (JAK) inhibitors] have been used for the treatment of patients with ARD. For many of these drugs, especia

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