Relevant bibliographies by topics / TCR signal

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'TCR signal'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "TCR signal"

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Erman, Batu, Terry I. Guinter та Alfred Singer. "Defined αβ T Cell Receptors with Distinct Ligand Specificities Do Not Require Those Ligands to Signal Double Negative Thymocyte Differentiation". Journal of Experimental Medicine 199, № 12 (2004): 1719–24. http://dx.doi.org/10.1084/jem.20032204.

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During T cell development in the thymus, pre–T cell receptor (TCR) complexes signal CD4− CD8− (double negative [DN]) thymocytes to differentiate into CD4+ CD8+ (double positive [DP]) thymocytes, and they generate such signals without apparent ligand engagements. Although ligand-independent signaling is unusual and might be unique to the pre-TCR, it is possible that other TCR complexes such as αβ TCR or αγ TCR might also be able to signal the DN to DP transition in the absence of ligand engagement if they were expressed on DN thymocytes. Although αγ TCR complexes efficiently signal DN thymocyte
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Candéias, S., K. Muegge, and S. K. Durum. "Junctional diversity in signal joints from T cell receptor beta and delta loci via terminal deoxynucleotidyl transferase and exonucleolytic activity." Journal of Experimental Medicine 184, no. 5 (1996): 1919–26. http://dx.doi.org/10.1084/jem.184.5.1919.

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The site-specific V(D)J recombination reaction necessary to assemble the genes coding for immunoglobulin (Ig) and T cell receptor (TCR) variable regions is initiated by a precise double strand cut at the border of the recombination signals flanking the genes. Extensive processing of the coding ends before their ligation accounts for most of the Ig and TCR repertoire diversity. This processing includes both base additions to and loss from the coding ends. On the other hand, it has generally been thought that signal ends are not modified before they are fused, and that signal joints consist of a
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Zinzow-Kramer, Wendy M., Arthur Weiss, and Byron B. Au-Yeung. "Adaptation by naïve CD4+ T cells to self-antigen–dependent TCR signaling induces functional heterogeneity and tolerance." Proceedings of the National Academy of Sciences 116, no. 30 (2019): 15160–69. http://dx.doi.org/10.1073/pnas.1904096116.

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Naïve CD4+ T cells experience weak T cell receptor (TCR) signals induced by self-peptides presented by MHC II. To investigate how these “basal” TCR signals influence responses to agonist TCR ligand stimulation, we analyzed naïve CD4+ cells expressing varying amounts of CD5, Ly6C, and Nur77-GFP, markers that reflect the strength of basal TCR signaling. Phenotypic analyses indicate that the broadest range of basal TCR signal strength can be visualized by a combination of Nur77-GFP and Ly6C. A range of basal TCR signaling is detectable even in populations that express identical TCRs. Whereas mode
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Shores, Elizabeth W., Tom Tran, Alexander Grinberg, Connie L. Sommers, Howard Shen та Paul E. Love. "Role of the Multiple T Cell Receptor (TCR)-ζ Chain Signaling Motifs in Selection of the T Cell Repertoire". Journal of Experimental Medicine 185, № 5 (1997): 893–900. http://dx.doi.org/10.1084/jem.185.5.893.

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Immature thymocytes undergo a selection process within the thymus based on their T cell antigen receptor (TCR) specificity that results either in their maturation into functionally competent, self-MHC–restricted T cells (positive selection) or their deletion (negative selection). The outcome of thymocyte selection is thought to be controlled by signals transduced by the TCR that vary in relation to the avidity of the TCR–ligand interaction. The TCR is composed of four distinct signal transducing subunits (CD3-γ, -δ, -ε, and ζ) that contain either one (CD3-γ, -δ, -ε) or three (-ζ) signaling mot
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Delgado, Pilar, and Balbino Alarcón. "An orderly inactivation of intracellular retention signals controls surface expression of the T cell antigen receptor." Journal of Experimental Medicine 201, no. 4 (2005): 555–66. http://dx.doi.org/10.1084/jem.20041133.

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Exit from the endoplasmic reticulum (ER) is an important checkpoint for proper assembly of multimeric plasma membrane receptors. The six subunits of the T cell receptor (TCR; TCRα, TCRβ, CD3γ, CD3δ, CD3ε, and CD3ζ) are each endowed with ER retention/retrieval signals, and regulation of its targeting to the plasma membrane is therefore especially intriguing. We have studied the importance of the distinct ER retention signals at different stages of TCR intracellular assembly. To this end, we have characterized first the presence of ER retention signals in CD3γ. Despite the presence of multiple E
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Wu, Hanchih, Ashley Witzl, and Hideki Ueno. "Assessment of TCR signal strength of antigen-specific memory CD8+ T cells in human blood." Blood Advances 3, no. 14 (2019): 2153–63. http://dx.doi.org/10.1182/bloodadvances.2019000292.

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Abstract Assessment of the quality and the breadth of antigen (Ag)-specific memory T cells in human samples is of paramount importance to elucidate the pathogenesis and to develop new treatments in various diseases. T-cell receptor (TCR) signal strength, primarily controlled by TCR affinity, affects many fundamental aspects of T-cell biology; however, no current assays for detection of Ag-specific CD8+ T cells can assess their TCR signal strength in human samples. Here, we provide evidence that interferon regulatory factor 4 (IRF4), a transcription factor rapidly upregulated in correlation wit
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Neier, Steven C., Alejandro Ferrer, Katelynn M. Wilton та ін. "The early proximal αβ TCR signalosome specifies thymic selection outcome through a quantitative protein interaction network". Science Immunology 4, № 32 (2019): eaal2201. http://dx.doi.org/10.1126/sciimmunol.aal2201.

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During αβ T cell development, T cell antigen receptor (TCR) engagement transduces biochemical signals through a protein-protein interaction (PPI) network that dictates dichotomous cell fate decisions. It remains unclear how signal specificity is communicated, instructing either positive selection to advance cell differentiation or death by negative selection. Early signal discrimination might occur by PPI signatures differing qualitatively (customized, unique PPI combinations for each signal), quantitatively (graded amounts of a single PPI series), or kinetically (speed of PPI pathway progress
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Fraser, J. D., and A. Weiss. "Regulation of T-cell lymphokine gene transcription by the accessory molecule CD28." Molecular and Cellular Biology 12, no. 10 (1992): 4357–63. http://dx.doi.org/10.1128/mcb.12.10.4357.

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T-cell activation results in the production of multiple lymphokines. Efficient lymphokine gene expression appears to require both T-cell antigen receptor (TCR) signal transduction and an uncharacterized second or costimulatory signal. CD28 is a T-cell differentiation antigen that can generate intracellular signals that synergize with those of the TCR to increase T-cell activation and interleukin-2 (IL-2) gene expression. In these studies, we have examined the effect of CD28 signal transduction on granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin 3 (IL-3), and gamma interfe
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Fraser, J. D., and A. Weiss. "Regulation of T-cell lymphokine gene transcription by the accessory molecule CD28." Molecular and Cellular Biology 12, no. 10 (1992): 4357–63. http://dx.doi.org/10.1128/mcb.12.10.4357-4363.1992.

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T-cell activation results in the production of multiple lymphokines. Efficient lymphokine gene expression appears to require both T-cell antigen receptor (TCR) signal transduction and an uncharacterized second or costimulatory signal. CD28 is a T-cell differentiation antigen that can generate intracellular signals that synergize with those of the TCR to increase T-cell activation and interleukin-2 (IL-2) gene expression. In these studies, we have examined the effect of CD28 signal transduction on granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin 3 (IL-3), and gamma interfe
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Smith-Garvin, Jennifer E., Jeremy C. Burns, Mercy Gohil, et al. "T-cell receptor signals direct the composition and function of the memory CD8+ T-cell pool." Blood 116, no. 25 (2010): 5548–59. http://dx.doi.org/10.1182/blood-2010-06-292748.

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Abstract SH2 domain-containing leukocyte phosphoprotein of 76 kDa (SLP-76) nucleates a signaling complex critical for T-cell receptor (TCR) signal propagation. Mutations in the tyrosines of SLP-76 result in graded defects in TCR-induced signals depending on the tyrosine(s) affected. Here we use 2 strains of genomic knock-in mice expressing tyrosine to phenylalanine mutations to examine the role of TCR signals in the differentiation of effector and memory CD8+ T cells in response to infection in vivo. Our data support a model in which altered TCR signals can determine the rate of memory versus
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Dissertations / Theses on the topic "TCR signal"

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Frazer, Gordon Lee. "How TCR signal strength controls CTL polarisation for target killing." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/277687.

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Cytotoxic T lymphocytes (CTL) are major effector cells in the adaptive immune response against intracellular pathogens and cancers, killing targets with high precision. Precision is achieved through the specificity of the clonally expressed T cell receptor (TCR). TCRs recognise a specific peptide chain loaded into a major-histocompatability complex, triggering signalling, inducing the CTL to attach and kill target cells. Key stages in this attack are the initial conjugation followed by polarisation and docking of the centrosome to the junction of the two cells, the immune synapse (IS). This fo
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Conley, James M. "TCR Signal Strength Controls Dynamic NFAT Activation Threshold and Graded IRF4 Expression in CD8+ T Cells." eScholarship@UMMS, 2019. https://escholarship.umassmed.edu/gsbs_diss/1019.

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TCR signal strength is critical for CD8+ T cell clonal expansion after antigen stimulation. Levels of the transcription factor IRF4 control the magnitude of this process through induction of genes involved in proliferation and glycolytic metabolism. The signaling mechanism connecting graded TCR signaling to the generation of varying amounts of IRF4 is not well understood. Here, using multiple methods to vary TCR signal strength and measure changes in transcriptional activation in single CD8+ T cells, we connect antigen potency to the kinetics of NFAT activation and Irf4 mRNA expression. T cell
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Matsuo, Takashi. "Strain-Specific Manifestation of Lupus-like Systemic Autoimmunity Caused by Zap70 Mutation." Kyoto University, 2019. http://hdl.handle.net/2433/244498.

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Tomassian, Tamar Kathy. "A role for scaffolds in synaptic organization, regulation of TCR signal specificity and functional outcome in CD8 cells." Diss., Restricted to subscribing institutions, 2009. http://proquest.umi.com/pqdweb?did=1997614311&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.

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Touvrey, Cédric. "Analyse de la recombinaison des gènes TCRAD : réarrangements radio-induits et structure des jonctions signal." Phd thesis, Université Joseph Fourier (Grenoble), 2005. http://tel.archives-ouvertes.fr/tel-00175283.

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La différenciation des lymphocytes T dans le thymus est strictement contrôlée par le réarrangement des gènes codants pour les chaînes du TCR et leur expression en surface dans le cadre du pré-TCR ou du TCR. Les souris incapables d'assembler un pré-TCR présentent un blocage précoce du développement des thymocytes. Nous avons montré que l'irradiation de souris CD3ε-/-, qui sont déficientes en pré-TCR, restaure la différenciation des thymocytes par des voies différentes selon que p53 soit présente ou non. En réponse à l'irradiation, il existe une dissociation temporelle de l'activation des voies
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Dong, Shen. "Caractérisation de deux nouveaux mécanismes de régulation de l'initiation du signal induit par le récepteur pour l'antigène du lymphocyte T." Paris 6, 2009. http://www.theses.fr/2009PA066163.

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Mes travaux montrent que la stimulation du récepteur pour l’antigène du lymphocyte T induit la phosphorylation sur tyrosine et le recrutement à la protéine d’échafaudage LAT de l’adaptateur inhibiteur Dok-2. Ce dernier et son homologue Dok-1 sont alors caractérisés comme modulateurs du signal précoce induit par l’engagement du TCR et comme régulateurs du seuil d’activation du lymphocyte T. Par ailleurs, j’ai montré que les lymphocytes T CD4+ naïfs présentent une activation basale de Lck et Fyn qui n’est pas augmentée après stimulation du TCR. L’inhibition stable de l’expression de LAT par inte
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Soula-Rothhut, Mahdhia. "Etude de la phosphorylation de la P56Ick et détection des sites de phosphorylation par les voies de signalisation CD4 et TcR/CD3 dans les cellules T." Paris 7, 1993. http://www.theses.fr/1993PA077343.

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Dans cette thèse nous avons analysé les mécanismes de phosphorylation de la p56Ick et son activité kinase après stimulation des cellules Jurkat par des anticorps anti-CD4, les gp160 ou gp 120 du VIH et des anticorps anti-TcR/CD3. Nous avons essayé de rapprocher ce phénomène avec un modèle d'adhésion nécessitant la voie du CD4 et un modèle de sécrétion de cytokines (IL-2) par la stimulation du TcR/CD3. Ces deux voies de signalisation n'induisent pas le même effet cellulaire (IPs, Ca⁺⁺ prolifération), mais le point commun réside dans la phosphorylation de la p56Ick. Nous avons démontré que les l
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Alanio, Bréchot Cécile. "Impact d'une infection virale chronique sur le répertoire T CD8 préimmun : à quel moment perd-on sa naiveté?" Thesis, Paris 6, 2015. http://www.theses.fr/2015PA066376/document.

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Le répertoire T CD8 préimmun correspond aux lymphocytes T spécifiques d'antigène circulant en périphérie, et n'ayant pas encore été activés. Ces cellules sont très rares, et de ce fait, n'ont jusqu'ici pas pu être étudiées de façon approfondie. Nous avons dans un premier temps développé un protocole d'enrichissement basé sur la technologie des tétramères. Nous avons pu détecter et énumérer des lymphocytes T CD8 naïfs spécifiques d'antigènes dans le sang de sujets sains. Nous avons ensuite utilisé cet outil pour évaluer le répertoire T préimmun de patients chroniquement infectés par le virus de
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Del, Río Iñiguez Iratxe. "Intracellular vesicle traffic, immunological synapse and T cell activation. Modulation by Human Immunodeficiency Virus type 1 Rac1-Rab11-FIP3 regulatory hub coordinates vesicle traffic with actin remodeling and T cell activation Rab11-FIP3 regulation of Lck endosomal traffic controls TCR signal transduction." Thesis, Sorbonne université, 2018. http://www.theses.fr/2018SORUS561.

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La formation et les fonctions de la synapse immunologique sont le résultat d’un processus de polarisation cellulaire du lymphocyte T. Ce processus dépend de l’action coordonnée du cytosquelette d’actine et de microtubules, et du trafic vésiculaire intracellulaire. Le récepteur T ainsi que des protéines impliquées dans sa signalisation intracellulaire sont associés à la membrane plasmique et à des compartiments vésiculaires endosomiaux, et circulent en continu entre ces deux localisations. Je montre dans cette thèse que la tyrosine kinase Lck et la GTPase Rac1 sont associés aux endosomes exprim
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Kang, Ling 1962. "TCM schemes with partially overlapped signal constellation." Thesis, McGill University, 1991. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=60046.

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This thesis describes the evolution of Trellis Coded Modulation (TCM) technique and then develops the Analytically Described Trellis Codes with Partially Overlapped Signal Constellation for AWGN channels. This development is shown to obtain a performance gain over the TCM with conventional signal constellation. The new signal constellation is first introduced. A few examples (for one-, two-, and high-dimensional signal sets) are then given to show the performance gain due to the overlap of signal constellation. Bit error probability analysis is carried out for these examples.
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Books on the topic "TCR signal"

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K, Havrilla, Kollar István, and International Measurement Confederation, eds. Signal processing in measurement: 6th Symposium of the Technical Committee on Measurement Theory (TC7) : Budapest, Hungary, June 10-12, 1987 : proceedings. Nova Science Publishers, 1988.

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Raghavan, S. V., and Bijendra N. Jain. Computer networks, architecture and applications: Proceedings of the IFIP TC6 conference 1994. Springer, 1995.

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Dabbous, Walid, and Christophe Diot. Protocols for High-Speed Networks V: TC6 WG6.1/6.4 Fifth International Workshop on Protocols for High-Speed Networks (PfHSN '96) 28-30 October 1996, Sophia Antipolis, France. Springer US, 1997.

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IFIP TC6 WG6.1 International Workshop on Quality of Service (5th 1997 New York, N.Y.). Building QoS into distributed systems: IFIP TC6 WG6.1 Fifth International Workshop on Quality of Service (IWQOS '97), 21-23 May 1997, New York, USA. Springer, 1997.

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IFIP TC6 WG6.2 International Conference on Broadband Communications (4th 1998 Stuttgart, Germany). Broadband communications: The future of telecommunications ; IFIP TC6/WG6.2 Fourth International Conference on Broadband Communications (BC'98) 1st-3rd April 1998, Stuttgart, Germany. Springer, 1998.

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Appendixes to TCRP RRD 84: Audible Signals for Pedestrian Safety in LRT Environments. Transportation Research Board, 2007. http://dx.doi.org/10.17226/23173.

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du Toit, Fanie. Dealing with a Violent Past. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190881856.003.0004.

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This chapter focuses on whether the TRC maintained momentum toward inclusivity and fairness built up during the early 1990s, or if it embodied the first signs of South Africa’s stepping away from these guiding values. I argue that instead of the result of security-sector blackmail, amnesty as a tool of reconciliation went through two distinct phases that showed political dexterity and a measure of increasingly civic inclusivity. I also argue that liberals get it wrong when they accuse Archbishop Tutu of moral overreach that excluded non-Christians. Instead, the archbishop spoke in language fam
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Donaj, Gregor, and Iztok Kramberger. Elektronski sestavi: Laboratorijske vaje. University of Maribor Press, 2021. http://dx.doi.org/10.18690/978-961-286-427-9.

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Gradivo vsebuje navodila za laboratorijske vaje pri pred-metu Elektronski sestavi za ˇstudente druge stopnje magistrskega ˇstudijskega programa Elektrotehnika, smer elektronika, in druge sto-pnje magistrskega ˇstudijskega programa Telekomunikacije. V navodilih je 5 laboratorijskih vaj, ki obravnavajo podatkovne pretvornike ter obdelavo, tvorjenje in prepoznavanja digitalnih signalov. Vaje ob-segajo podatkovne pretvornike, digitalne filtre, neposredno digitalno sintezo, digitalno fazno sklenjeno zanko in digitalne modulacijske sheme.
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Advanced S-band studies using the TDRSS communication satellite: Final report. New Mexico State University, Dept. of Electrical and Computer Programming, 1994.

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P, Osborne William, Fan Yping, and United States. National Aeronautics and Space Administration., eds. Advanced S-band studies using the TDRSS communication satellite: Final report. New Mexico State University, Dept. of Electrical and Computer Programming, 1994.

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Book chapters on the topic "TCR signal"

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Neagu, Monica, and Carolina Constantin. "Signal Transduction in Immune Cells and Protein Kinases." In Advances in Experimental Medicine and Biology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-49844-3_5.

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AbstractImmune response relies upon several intracellular signaling events. Among the protein kinases involved in these pathways, members of the protein kinase C (PKC) family are prominent molecules because they have the capacity to acutely and reversibly modulate effector protein functions, controlling both spatial distribution and dynamic properties of the signals. Different PKC isoforms are involved in distinct signaling pathways, with selective functions in a cell-specific manner.In innate system, Toll-like receptor signaling is the main molecular event triggering effector functions. Various isoforms of PKC can be common to different TLRs, while some of them are specific for a certain type of TLR. Protein kinases involvement in innate immune cells are presented within the chapter emphasizing their coordination in many aspects of immune cell function and, as important players in immune regulation.In adaptive immunity T-cell receptor and B-cell receptor signaling are the main intracellular pathways involved in seminal immune specific cellular events. Activation through TCR and BCR can have common intracellular pathways while others can be specific for the type of receptor involved or for the specific function triggered. Various PKC isoforms involvement in TCR and BCR Intracellular signaling will be presented as positive and negative regulators of the immune response events triggered in adaptive immunity.
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Venu, Y., T. Nireekshana, B. Phanisaikrishna, Ramavath Gnanendar, and S. Ravikumar. "Reducing TCR Harmonics Using Sequential Switching." In Advances in Automation, Signal Processing, Instrumentation, and Control. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-8221-9_233.

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Liu, Hsi, and Harvey Cantor. "Alternative Pathways of Signal Transduction after Ligation of the TCR by Bacterial Superantigen." In T Lymphocytes. Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3054-1_18.

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Flamson, Thomas J., and Gregory A. Bryant. "Signals of humor." In Topics in Humor Research. John Benjamins Publishing Company, 2013. http://dx.doi.org/10.1075/thr.1.04fla.

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Liu, Weixiang, Tianfu Wang, Siping Chen, Laurence Luo, and Xiaoyi Wang. "Complex Frequency Features for TCD Signal Analysis." In IFMBE Proceedings. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-29305-4_143.

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Nederkoorn, Paul H. J., Henk Timmerman, and Gabriëlle M. Donné-Op den Kelder. "The (Extended) Ternary Complex Model ([E]TCM) for G Protein Activation." In Signal Transduction by G Protein-Coupled Receptors. Springer US, 1997. http://dx.doi.org/10.1007/978-1-4684-1407-3_5.

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Hrvat, Faris, Osman Hasanić, Amina Aleta, Amel Spahić, Amra Džuho, and Mirsada Hukić. "Comparison of Biofilm Category Determination Using TCP Method Depending on Signal Molecule Adherence." In IFMBE Proceedings. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-73909-6_67.

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Goudru, N. G. "Performance Analysis of TCP in Presence of Nonresponsive Traffic in Wireless Networks." In Advances in VLSI, Signal Processing, Power Electronics, IoT, Communication and Embedded Systems. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-0443-0_13.

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Olmo, Nieves, and M. Antonia Lizarbe. "Signal Transduction Through Laminin Receptors. Effects of Extracellular Matrix on BCS-TC2 Adenocarcinoma Cells." In Cell Signal Transduction, Second Messengers, and Protein Phosphorylation in Health and Disease. Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-1879-2_22.

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Klemm, Fabius, Srikanth V. Krishnamurthy, and Satish K. Tripathi. "Alleviating Effects of Mobility on TCP Performance in Ad Hoc Networks Using Signal Strength Based Link Management." In Personal Wireless Communications. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-540-39867-7_59.

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Conference papers on the topic "TCR signal"

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Imeci, S. Taha, Zeliha Apaydin, Erdem Demircioglu, and Murat H. Sazli. "S-band TCR patch antenna design for nano satellites." In 2010 IEEE 18th Signal Processing and Communications Applications Conference (SIU). IEEE, 2010. http://dx.doi.org/10.1109/siu.2010.5648884.

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Firiti, A., G. Haller, F. Beaudoin, P. Perdu, D. Lewis, and P. Fouillat. "Guideline for Interpreting IR Laser Stimulation Signal on Semiconductors for Materials and for Improving Failure Analysis Flow." In ISTFA 2005. ASM International, 2005. http://dx.doi.org/10.31399/asm.cp.istfa2005p0121.

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Abstract Infra-red Thermal Laser Stimulation (TLS) signatures obtained on semiconductor materials can be difficult to interpret and to distinguish from signatures from metallic materials. Investigations presented here consist in the study of TLS signals on unsilicided/silicided polycrystalline and diffused silicon resistors of 0.18µm technology. The influence of each process parameter on the TLS signal has been observed and evaluated from the front and back side of the circuit. This allowed us to quantify the effect of the silicon substrate thickness on TLS signal detection and to determine th
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Abhyankar, B. Gajanana, K. N. Shubhanga, and H. Girisha Navada. "Analysis of a laboratory scale three-phase FC-TCR-based static VAr compensator." In 2017 IEEE International Conference on Signal Processing, Informatics, Communication and Energy Systems (SPICES). IEEE, 2017. http://dx.doi.org/10.1109/spices.2017.8091302.

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Peralta, Eigen, Dan Lu, Mark Landon, et al. "Abstract 332: Chimeric fusion receptors provide a CD3-mediated activation signal to off-the-shelf iPSC-derived TCR-less CAR-T cells for enhanced efficacy." In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-332.

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Odegard, Charles, and Craig Lambert. "Comparative TDR Analysis as a Packaging FA Tool." In ISTFA 1999. ASM International, 1999. http://dx.doi.org/10.31399/asm.cp.istfa1999p0049.

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Abstract Time domain reflectometry (TDR) is increasingly being utilized as a failure analysis tool in the semiconductor industry. TDR can provide fast, nondestructive analysis of packaged integrated circuits. With one measurement, TDR analysis can provide instant identification of the general region of the fail site, whether it exists in the substrate, interconnect region, or in the die. A digital sampling oscilloscope with a TDR module supplies a fast risetime voltage edge to the signal pin of interest, and then records the subsequent voltage edge reflections. The time delay between the incid
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Liu, Zhiliang, Yaqiang Jin, and Ming J. Zuo. "Time-Frequency Representation Based on Robust Local Mean Decomposition." In ASME 2016 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/imece2016-65184.

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Fourier transform based frequency representation makes an underlying assumption of stationarity and linearity for the target signal whose spectrum is to be computed, and thus it is unable to track time varying characteristics of non-stationary signals that also widely exist in the physical world. Time-frequency representation (TFR) is a technique to reveal useful information included in the signals, and thus the TFR methods are very attractive to the scientific and engineering world. Local mean decomposition (LMD) is a TFR technique used in many fields, e.g. machinery fault diagnosis. Similar
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Stuhr, Ben, and Rui Liu. "A Flexible Similarity Based Algorithm for Tool Condition Monitoring." In ASME 2021 16th International Manufacturing Science and Engineering Conference. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/msec2021-62021.

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Abstract To realize smart manufacturing in various machining processes, tool condition monitoring (TCM) systems are employed to detect the state of the tool in optimizing tool conditions and preventing catastrophic failures. Common types of TCM systems include part-specific methods and generic methods. However, many developed TCM systems lack flexibility and require extensive set-up. To address these issues, the proposed algorithm takes advantage of repetitive machining operations in manufacturing settings and adopts similarity analysis to realize tool condition monitoring by comparing the sig
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Illmann, Raik, Maik Rosenberger, and Gunther Notni. "A development overview of a signal flow model for spectral data with a final assessment under a practical point of view." In Joint TC1 - TC2 International Symposium on Photonics and Education in Measurement Science 2019, edited by Bernhard Zagar, Pawel Mazurek, Maik Rosenberger, and Paul-Gerald Dittrich. SPIE, 2019. http://dx.doi.org/10.1117/12.2531944.

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Konkol, Nicholas. "TDR Analysis on Short Transmission Lines." In ISTFA 2014. ASM International, 2014. http://dx.doi.org/10.31399/asm.cp.istfa2014p0391.

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Abstract Transmission line analysis is done in electrical failure analysis labs in order to find root causes that result in system level failures. After a fault is narrowed to a particular signal in a system, a Time Domain Reflectometer (TDR) can be used to analyze the physical transmission line associated with the signal. The transmission lines on smartphones often have inaccessible signal vias, few or no ground vias, probe points that are difficult to see, and short transmission lines. One solution that can alleviate these problems is to design a TDR Accessory Card. This paper discusses the
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Forsythe, K. W., P. Monticciolo, and J. R. Sklar. "Spatial adaptive filtering for LPI signal detection." In Proceedings of TCC'94 - Tactical Communications Conference. IEEE, 1994. http://dx.doi.org/10.1109/tcc.1994.472092.

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Reports on the topic "TCR signal"

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Stevens, Jeffrey P. General TCF Closure Tasks in the U.S. Army Signal Corps. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada612295.

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Fu, C. Y., and D. Spencer. Advanced Analog Signal Processing for Fuzing Final Report CRADA No. TC-1306-96. Office of Scientific and Technical Information (OSTI), 2018. http://dx.doi.org/10.2172/1418950.

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