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Dissertations / Theses on the topic 'TCR signal'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Frazer, Gordon Lee. "How TCR signal strength controls CTL polarisation for target killing." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/277687.

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Cytotoxic T lymphocytes (CTL) are major effector cells in the adaptive immune response against intracellular pathogens and cancers, killing targets with high precision. Precision is achieved through the specificity of the clonally expressed T cell receptor (TCR). TCRs recognise a specific peptide chain loaded into a major-histocompatability complex, triggering signalling, inducing the CTL to attach and kill target cells. Key stages in this attack are the initial conjugation followed by polarisation and docking of the centrosome to the junction of the two cells, the immune synapse (IS). This fo

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2

Conley, James M. "TCR Signal Strength Controls Dynamic NFAT Activation Threshold and Graded IRF4 Expression in CD8+ T Cells." eScholarship@UMMS, 2019. https://escholarship.umassmed.edu/gsbs_diss/1019.

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TCR signal strength is critical for CD8+ T cell clonal expansion after antigen stimulation. Levels of the transcription factor IRF4 control the magnitude of this process through induction of genes involved in proliferation and glycolytic metabolism. The signaling mechanism connecting graded TCR signaling to the generation of varying amounts of IRF4 is not well understood. Here, using multiple methods to vary TCR signal strength and measure changes in transcriptional activation in single CD8+ T cells, we connect antigen potency to the kinetics of NFAT activation and Irf4 mRNA expression. T cell

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3

Matsuo, Takashi. "Strain-Specific Manifestation of Lupus-like Systemic Autoimmunity Caused by Zap70 Mutation." Kyoto University, 2019. http://hdl.handle.net/2433/244498.

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4

Tomassian, Tamar Kathy. "A role for scaffolds in synaptic organization, regulation of TCR signal specificity and functional outcome in CD8 cells." Diss., Restricted to subscribing institutions, 2009. http://proquest.umi.com/pqdweb?did=1997614311&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.

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5

Touvrey, Cédric. "Analyse de la recombinaison des gènes TCRAD : réarrangements radio-induits et structure des jonctions signal." Phd thesis, Université Joseph Fourier (Grenoble), 2005. http://tel.archives-ouvertes.fr/tel-00175283.

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La différenciation des lymphocytes T dans le thymus est strictement contrôlée par le réarrangement des gènes codants pour les chaînes du TCR et leur expression en surface dans le cadre du pré-TCR ou du TCR. Les souris incapables d'assembler un pré-TCR présentent un blocage précoce du développement des thymocytes. Nous avons montré que l'irradiation de souris CD3ε-/-, qui sont déficientes en pré-TCR, restaure la différenciation des thymocytes par des voies différentes selon que p53 soit présente ou non. En réponse à l'irradiation, il existe une dissociation temporelle de l'activation des voies

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6

Dong, Shen. "Caractérisation de deux nouveaux mécanismes de régulation de l'initiation du signal induit par le récepteur pour l'antigène du lymphocyte T." Paris 6, 2009. http://www.theses.fr/2009PA066163.

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Mes travaux montrent que la stimulation du récepteur pour l’antigène du lymphocyte T induit la phosphorylation sur tyrosine et le recrutement à la protéine d’échafaudage LAT de l’adaptateur inhibiteur Dok-2. Ce dernier et son homologue Dok-1 sont alors caractérisés comme modulateurs du signal précoce induit par l’engagement du TCR et comme régulateurs du seuil d’activation du lymphocyte T. Par ailleurs, j’ai montré que les lymphocytes T CD4+ naïfs présentent une activation basale de Lck et Fyn qui n’est pas augmentée après stimulation du TCR. L’inhibition stable de l’expression de LAT par inte

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7

Soula-Rothhut, Mahdhia. "Etude de la phosphorylation de la P56Ick et détection des sites de phosphorylation par les voies de signalisation CD4 et TcR/CD3 dans les cellules T." Paris 7, 1993. http://www.theses.fr/1993PA077343.

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Dans cette thèse nous avons analysé les mécanismes de phosphorylation de la p56Ick et son activité kinase après stimulation des cellules Jurkat par des anticorps anti-CD4, les gp160 ou gp 120 du VIH et des anticorps anti-TcR/CD3. Nous avons essayé de rapprocher ce phénomène avec un modèle d'adhésion nécessitant la voie du CD4 et un modèle de sécrétion de cytokines (IL-2) par la stimulation du TcR/CD3. Ces deux voies de signalisation n'induisent pas le même effet cellulaire (IPs, Ca⁺⁺ prolifération), mais le point commun réside dans la phosphorylation de la p56Ick. Nous avons démontré que les l

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8

Alanio, Bréchot Cécile. "Impact d'une infection virale chronique sur le répertoire T CD8 préimmun : à quel moment perd-on sa naiveté?" Thesis, Paris 6, 2015. http://www.theses.fr/2015PA066376/document.

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Le répertoire T CD8 préimmun correspond aux lymphocytes T spécifiques d'antigène circulant en périphérie, et n'ayant pas encore été activés. Ces cellules sont très rares, et de ce fait, n'ont jusqu'ici pas pu être étudiées de façon approfondie. Nous avons dans un premier temps développé un protocole d'enrichissement basé sur la technologie des tétramères. Nous avons pu détecter et énumérer des lymphocytes T CD8 naïfs spécifiques d'antigènes dans le sang de sujets sains. Nous avons ensuite utilisé cet outil pour évaluer le répertoire T préimmun de patients chroniquement infectés par le virus de

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9

Del, Río Iñiguez Iratxe. "Intracellular vesicle traffic, immunological synapse and T cell activation. Modulation by Human Immunodeficiency Virus type 1 Rac1-Rab11-FIP3 regulatory hub coordinates vesicle traffic with actin remodeling and T cell activation Rab11-FIP3 regulation of Lck endosomal traffic controls TCR signal transduction." Thesis, Sorbonne université, 2018. http://www.theses.fr/2018SORUS561.

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La formation et les fonctions de la synapse immunologique sont le résultat d’un processus de polarisation cellulaire du lymphocyte T. Ce processus dépend de l’action coordonnée du cytosquelette d’actine et de microtubules, et du trafic vésiculaire intracellulaire. Le récepteur T ainsi que des protéines impliquées dans sa signalisation intracellulaire sont associés à la membrane plasmique et à des compartiments vésiculaires endosomiaux, et circulent en continu entre ces deux localisations. Je montre dans cette thèse que la tyrosine kinase Lck et la GTPase Rac1 sont associés aux endosomes exprim

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10

Kang, Ling 1962. "TCM schemes with partially overlapped signal constellation." Thesis, McGill University, 1991. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=60046.

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This thesis describes the evolution of Trellis Coded Modulation (TCM) technique and then develops the Analytically Described Trellis Codes with Partially Overlapped Signal Constellation for AWGN channels. This development is shown to obtain a performance gain over the TCM with conventional signal constellation. The new signal constellation is first introduced. A few examples (for one-, two-, and high-dimensional signal sets) are then given to show the performance gain due to the overlap of signal constellation. Bit error probability analysis is carried out for these examples.

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11

Saini, Manoj. "The role of TCR and cytokine signals in naïve T cell homeostasis." Thesis, University College London (University of London), 2008. http://discovery.ucl.ac.uk/1446076/.

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The peripheral T cell compartment is maintained at a constant size, resulting from a balance of cell development, survival, proliferation and death. Transmission of signals through the TCR and IL-7R on the T cell surface is involved in regulating all these processes, however the precise manner in which these signals together maintain T cell homeostasis is unclear. To investigate the contribution of TCR and IL-7 signals to naive T cell homeostatic responses we established two model systems. To specifically address the role of homeostatic TCR signalling in the development and maintenance of the

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12

Khattar, Mithun. "Modulation of TCR Signals Reprograms Immune Tolerance in Transplantation and Type-1 Diabetes." University of Toledo Health Science Campus / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=mco1329231545.

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13

Haughn, Loralee J. "Novel effects of interleukin-2 on signals generated thorugh the Ãß TcR/CD3 complex." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0004/NQ44450.pdf.

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14

Vahl, Johann Christoph. "TCR signals in the identity and function of mature NKT and regulatory T cells." Diss., Ludwig-Maximilians-Universität München, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-185653.

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15

Dias, Silvy da Rocha. "The function of CTLA-4 in the mechanism of negative regulatory costimulation of TCR mediated signals." Tese, Porto : Edição do Autor, 2002. http://catalogo.up.pt/F?func=find-b&local_base=UPB01&find_code=SYS&request=000090479.

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Dias, Silvy da Rocha. "The function of CTLA-4 in the mechanism of negative regulatory costimulation of TCR mediated signals." Doctoral thesis, Porto : Edição do Autor, 2002. http://hdl.handle.net/10216/64574.

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17

Karsikas, M. (Mari). "New methods for vectorcardiographic signal processing." Doctoral thesis, Oulun yliopisto, 2011. http://urn.fi/urn:isbn:9789514296086.

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Abstract Vectorcardiography (VCG) determines the direction and magnitude of the heart’s electrical forces. Interpretation of the digital three-dimensional vectorcardiography in clinical applications requires robust methods and novel approaches for calculating the vectorcardiographic features. This dissertation aimed to develop new methods for vectorcardiographic signal processing. The robustness of selected pre-processing and feature extraction algorithms was improved, novel methods for detecting the injured myocardial tissue from electrocardiogram (ECG) were devised, and dynamical behavior of

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18

Marvasti, Salman Alim. "Automated Detection, Classification and Denoising of Embolic Signals in TCD Ultrasound." Thesis, Imperial College London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502920.

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19

Franchini, Don-Marc. "Rôle des séquences signal de recombinaison dans le contrôle des réarrangements au locus TCRβ". Aix-Marseille 2, 2007. http://theses.univ-amu.fr.lama.univ-amu.fr/2007AIX22012.pdf.

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Les gènes codant pour les récepteurs antigéniques (TCR et Ig) sont assemblés par un processus de réarrangement somatique dénommé Recombinaison V(D)J. Ce mécanisme est ciblé au niveau de l’ADN par les séquences signal de recombinaison (RSS). Ce processus est en grande partie régulé par la structure de la chromatine. Cependant, d’autres mécanismes existent, qui opèrent au-delà de l’accessibilité, pour réguler plus finement la recombinaison. Un exemple est la restriction B12/23 qui inhibe, malgré la compatibilité 12/23, les réarrangements directs Vβ-Jβ, et par conséquent assure l’incorporation du

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20

Vahl, Johann Christoph [Verfasser], and Klaus [Akademischer Betreuer] Förstemann. "TCR signals in the identity and function of mature NKT and regulatory T cells / Johann Christoph Vahl. Betreuer: Klaus Förstemann." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2013. http://d-nb.info/1075456940/34.

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21

Peach, Megan L. "Molecular modeling of the bacterial chemotaxis receptors Tar and Trg /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/8123.

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22

Sawicka, Anna. "Aspects biophysiques de l'activation des cellules T." Thesis, Sorbonne Paris Cité, 2018. http://www.theses.fr/2018USPCB079.

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Les cellules T jouent différents rôles dans la réponse immunitaire adaptative : elles stimulent les cellules B à produire les anticorps ; elles sécrètent les cytokines qui dirigent l'action des autres cellules immunitaires ; elles tuent les cellules du corps infectées ou porteuses de mutations ; elles assurent la mémoire immunitaire, permettant de répondre plus vite en cas de nouvelle infection avec le même pathogène. Toutes les cellules T s'activent quand elles reconnaissent leur antigène spécifique : un peptide court présenté par le complexe majeur d'histocompatibilité exprimé à la surface d

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23

Taboada, Efren De Jesus Rangel. "Improved Signal Integrity in IEEE 1149.1 Boundary Scan Designs." Diss., CLICK HERE for online access, 2004. http://contentdm.lib.byu.edu/ETD/image/etd587.pdf.

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24

Matichak, Jonathan D. "The design, synthesis, and characterization of polymethine dyes for all-optical signal processing applications." Diss., Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/41050.

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Material development is necessary before all-optical signal processing (AOSP) can be realized. Traditional AOSP will require materials with a large magnitude of the real part of the third-order polarizability, while having a small imaginary magnitude of third-order polarizability. The aim of this thesis is to investigate the potential for polymethine dyes to be used for AOSP applications. The basic structure of a polymethine dye was synthetically modified in a variety of positions to observe the effects upon the linear and nonlinear optical properties. The modifications included variation

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Teo, Jia-Ling. "Presenilin-1 and TCF/[beta]-catenin signaling : effects on neuronal differentiation /." Thesis, Connect to this title online; UW restricted, 2003. http://hdl.handle.net/1773/9311.

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26

Shaw, Tyler H. "Effects of Signal Modality and Event Asynchrony on Vigilance Performance and Cerebral Hemovelocity." University of Cincinnati / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1154632131.

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27

Baker, Christine M. "The Mechanism of Assembly of the G-Protein Beta Gamma Subunit Dimer by CK2 Phosphorylated Phosducin-Like Protein and the Chaperonin Containing TCP-1." Diss., CLICK HERE for online access, 2006. http://contentdm.lib.byu.edu/ETD/image/etd1337.pdf.

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Afifi, Mohammed Ahmed Melegy Mohammed. "TCP FTAT (Fast Transmit Adaptive Transmission): A New End-To- End Congestion Control Algorithm." Cleveland State University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=csu1414689425.

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29

AMMAR, Moussa. "Optimisation d'un schéma de codage d'image à base d'une TCD. Application à un codeur JPEG pour l'enregistrement numérique à bas débit." Phd thesis, Télécom ParisTech, 2002. http://tel.archives-ouvertes.fr/tel-00005739.

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Nous considérons dans cette thèse le problème dotpimisation dun schéma de codage/décodage JPEG et le post-traitement de réduction des effets de blocs dans les images codées par JPEG.<br />Nous proposons tout dabord le filtrage de Wiener comme optimisation du banc de filtres de synthèse pour une distorsion minimale et nous cherchons par la suite une quantifcation optimisée. Lalgorithme itératif A1 réalise une optimisation conjointe des quantificateurs et du banc de filtres de synthèse. Les résultats experimentaux sur quelques images montrent que le gain total en terme de PSNR peut atteindre 1,3

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Drees, Christoph-Maximilian Peter [Verfasser], Marc [Akademischer Betreuer] [Gutachter] Schmidt-Supprian, Jürgen [Gutachter] Ruland, and Angela [Gutachter] Krackhardt. "The role of TCR signals and downstream events for NKT and regulatory T cell identity and function in the mouse / Christoph-Maximilian Peter Drees ; Gutachter: Jürgen Ruland, Angela Krackhardt, Marc Schmidt-Supprian ; Betreuer: Marc Schmidt-Supprian." München : Universitätsbibliothek der TU München, 2017. http://d-nb.info/1139843818/34.

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31

Ahmad, Kassem. "Protocoles, gestion et transmission sécurisée par chaos des clés secrètesPplications aux standards TCP/IP via DVB-S, UMTS, EPS." Nantes, 2013. http://archive.bu.univ-nantes.fr/pollux/show.action?id=819becae-9749-4a1d-80df-3cc673b27901.

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IP Multicast est supporté dans la nouvelle génération des systèmes satellitaires implémentant DVB-S (Digital Video Broadcasting via satellite). Dans ce type de communication, la sécurité, la commutation, et l’évolutivité sont les principaux défis. A ce propos, nous proposons un nouveau système de sécurité multicast basé sur : une méthode d’encapsulation améliorée du standard ULE qui peut opérer avec les approches de commutation ‘label ou self-switching’ afin d’assurer : un transfert efficace d’IP multicast, un mécanisme de sécurité très performant, et un système évolutif de gestion de clés à d

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Navaud, Olivier. "Analyse évolutive et fonctionnelle d’une famille de facteurs de transcription à domaine TCP chez les plantes." Toulouse 3, 2007. http://www.theses.fr/2007TOU30027.

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Les protéines TCP constituent une famille de facteurs de transcription spécifiques des végétaux impliqués dans la régulation de la morphologie des plantes. Ce travail a pour objectif d'étudier l'évolution et la fonction de ces protéines. Dans la première partie, une étude structurelle et évolutive de la famille TCP permet de dater l'apparition de la famille avant la divergence du groupe d'algues des Zygnémophytes, il y a entre 650 et 800 millions d'années et indique une expansion permanente de la famille TCP au cours de l'évolution des Phragmoplastophytes. Dans la seconde partie, une analyse f

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Sassatelli, Gilles. "Architectures reconfigurables dynamiquement pour les systèmes sur puce." Montpellier 2, 2002. http://www.theses.fr/2002MON20052.

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Odedo, Victor. "High resolution time reversal (TR) imaging based on spatio-temporal windows." Thesis, University of Manchester, 2017. https://www.research.manchester.ac.uk/portal/en/theses/high-resolution-time-reversal-tr-imaging-based-on-spatiotemporal-windows(f0589f73-901f-4de2-9886-7045b7f6cfd4).html.

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Through-the-wall Imaging (TWI) is crucial for various applications such as law enforcement, rescue missions and defense. TWI methods aim to provide detailed information of spaces that cannot be seen directly. Current state-of-the-art TWI systems utilise ultra-wideband (UWB) signals to simultaneously achieve wall penetration and high resolution. These TWI systems transmit signals and mathematically back-project the reflected signals received to image the scenario of interest. However, these systems are diffraction-limited and encounter problems due to multipath signals in the presence of multip

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Syed, Muhammad Fahad. "Various resource allocation and optimization strategies for high bit rate communications on power lines." Phd thesis, INSA de Rennes, 2010. http://tel.archives-ouvertes.fr/tel-00480261.

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Ces dernières années, le développement des réseaux de communication indoor et outdoor et l'augmentation du nombre d'applications conduisent à un besoin toujours croissant de transmission de données à haut débit. Parmi les nombreuses technologies concurrentes, les communications par courant porteur en ligne (CPL) ont leur place en raison des infrastructures déjà disponibles. La motivation principale de cette thèse est d'augmenter le débit et la robustesse des systèmes CPL à porteuses multiples afin qu'ils puissent être utilisés efficacement dans les réseaux domestiques et pour la domotique. Le

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Vallet, Mathieu. "Synthèse de fréquence multi-bandes couvrant les ondes millimétriques pour les applications WiFi-WiGig." Thesis, Bordeaux, 2015. http://www.theses.fr/2015BORD0407/document.

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L’ensemble des travaux présentés au sein de manuscrit porte sur la réalisation d’un synthétiseur de fréquences millimétriques capable de répondre aux besoins de la convergence WiFi-WiGig. Une première étude est réalisée dans le but de définir une architecture de synthétiseur de fréquence faible consommation adaptée aux standards du WiFi et du WiGig. L’ensemble des éléments composants la PLL sont par la suite détaillés, mettant en avant les avantages offerts par la technologie 28 nm FDSOI CMOS. Une étude plus approfondie des VCO millimétriques large bande et faible consommation est ensuite prés

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Lembard, Tomáš. "Speciální aplikace VoIP." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2011. http://www.nusl.cz/ntk/nusl-219188.

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The aim of this master's thesis is suggestion and following realization of voice transmission over the local network equipment and a description of used circuits and solutions in terms of hardware and software. This thesis deals with digitization of low-frequency signals, the structure of IP and UDP protocols, implementation of TCP/IP stack cIPS

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Eisfelder, Bartholomew Joseph. "The role of TCR and IL-4R signal integration in Th2 differentiation /." 2002. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:3070165.

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Pitcher, Lisa Anne. "The function of the TCR zeta zeta module in T cells." 2005. http://edissertations.library.swmed.edu/pdf/PitcherL042905/PitcherLisa.pdf.

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Rajagopal, Keshava. "Functional and molecular characterization of RIBP, an Rlk/Itk-binding adaptor protein involved in TCR signal transduction /." 2001. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:3006548.

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Thesis (Ph. D.)--University of Chicago, Faculty of the Division of the Biological Sciences and the Pritzker School of Medicine, Commitee on Immunology, June 2001.<br>Includes bibliographical references. Also available on the Internet.

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Sedwick, Caitlin E. "The roles of TCR, LFA-1 and CD28 in the function and organization of the immunological synapse /." 2001. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:3025462.

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Uche, Uzodinma Nnaemeka Xiong Na. "Development of specific [gamma][delta] T cell populations is critically affected by recombination signal sequence-associated restriction on TCR[delta] gene rearrangement." 2008. http://etda.libraries.psu.edu/theses/approved/PSUonlyIndex/ETD-3645/index.html.

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Liu, Chunyi, and 劉俊儀. "Pichia pastoris-recombinant Ganoderma lucidum LZ-8 protein interaction with CD45 and mediation of TCR signal transduction in the regulation of IL-2 secretion." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/46224073266580543191.

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碩士<br>國立陽明大學<br>醫學生物技術研究所<br>95<br>We previously demonstrated that Pichia pastoris-recombinant Ganoderma lucidum LZ-8 protein (rLZ-8) induces IL-2 expression via protein kinase-dependent signaling pathways. To continue our research, we were interested in the interaction of rLZ-8 and T cell surface membrane. We focused on three parts, i.e. T cell receptor (TCR) the proximal signalings, the signal transduction in the regulation of IL-2 secretion, and the putative rLZ-8 protein binding sites including CD45. Initially, we found that rLZ-8 dramatically induces phosphorylation of TCR-triggered proxi

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Furlong, Suzanne Joy. "Thy-1 Signaling in T cells is Weaker and Has Delayed Signaling Kinetics, Promotes Delayed Acquisition and Triggering of Cytotoxic Effector Function, and Preferentially Promotes IL-17A and IL-4 Production in Comparison to TcR Signaling." 2011. http://hdl.handle.net/10222/15491.

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Thy-1 is a glycosylphosphatidylinositol-anchored protein that is expressed on murine T lymphocytes and is involved in T cell-mediated immune responses. In the presence of costimulatory signals, monoclonal antibody (mAb)-induced signaling through Thy-1 is associated with hallmarks of T cell activation, including IL-2 production and T cell proliferation. Thy-1-induced signaling promotes cytotoxic effector molecule expression, but is unable to trigger delivery of the lethal hit to target cells, suggesting that Thy-1 provides an incomplete T cell receptor (TcR)-like signal. However, the effect of

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Tourish, John Patrick. "dspIP : a TCP/IP implementation for a Digital Signal Processor." 2011. http://hdl.handle.net/2152/22609.

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From the initial implementations for the DEC PDP-11 to those of today done for commodity PICs, the TCP/IP code stack continues to work its way into a smaller and more omnipresent class of devices. One shortcoming of current devices on the leading edge of this trend is that they belong more to the microcontroller categories, which typically lack any appreciable signal processing capability. Applications such as consumer electronics and wireless sensor networks could benefit greatly from single-chip network-capable devices which are based on a Digital Signal Processing (DSP) core rather than a

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Chang, Bo-Hsiu, and 張博修. "Analysis of Packet Signal with TCP Protocol and Network Simulator in Wireless Communication." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/46864241470734109978.

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碩士<br>中原大學<br>電機工程研究所<br>92<br>This thesis investigates the problem of analysis of package signal with TCP (Transport Control Protocol) protocol and <a href="http://www.ntsearch.com/search.php?q=network&v=56">network</a> simulator for <a href="http://www.ntsearch.com/search.php?q=wireless&v=56">wireless</a> communication. Via analyzing properties of <a href="http://www.ntsearch.com/search.php?q=wireless&v=56">wireless</a> packages and modifying the existent TCP protocol, an attempt to improve the efficiency of package transaction is proposed by the authors. The simulation results based on NS-2

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Zugelter, Joseph Zachary. "Time domain transmission line measurements with the speedy delivery signal." Thesis, 2010. http://hdl.handle.net/2152/ETD-UT-2010-12-2648.

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The Speedy Delivery (SD) waveform does not undergo dispersion in transmission lines. The waveform was first introduced by Dr. Robert Flake in US Patent 6,441,695 B1 issued on August 27, 2002. Use of the SD waveform allows for high precision time domain measurements on transmission lines. High precision time domain reflectometry (TDR) and time domain transmission (TDT) measurements are described. An example measurement is presented. The design of the experimental apparatus is detailed. Voltage bias adjustments are made during measurements to increase the repeatability. Voltage bias adjustments

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Adase, Christopher A. 1981. "The C-Terminus of Transmembrane Helix 2 (TM2) of the Escherichia coli Tar Chemorecptor Determines Signal Output and Ligand Sensitivity." Thesis, 2012. http://hdl.handle.net/1969.1/148210.

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Methyl-accepting chemotaxis proteins MCPs can bind one or more receptor- specific ligands. In the case of the Tar MCP of Escherichia coli (TarEc), a primary attractant ligand is aspartate. Its binding to the periplasmic domain of Tar generates a conformational change that is transmitted via helix 4 transmembrane helix 2 (TM2). An inward movement of TM2 initiates a transmembrane signal to the cytoplasmic HAMP (histidine kinases, adenyl cyclases, methyl-accepting proteins, phosphatases) domain. Baseline CheA kinase-stimulating activity and ligand-induced responses are both strongly influenced by

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周照凱. "I. Signal transduction of anchorage-independent growth and the role of Rac II.The role of normal Neu in TCC-Sup." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/70512686206761666242.

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碩士<br>國立成功大學<br>微生物暨免疫學研究所<br>86<br>Abstract Two cell lines designed 2-12 and 7-4 cells (derived from NIH/3T3) containing an inducible Ha-ras gene and an E.coli lacI repressor gene have been established in our laboratory. Tsai(1996) reported that Ha-ras oncogene overexpression and Insulin growth factor-1(IGF-1) stimulation were both required for 2-12 cells to form colonies in soft agar containing 10%AC-2TM(collistrum, a substitute of serum). Using this model we analyzed colony formation related signal transduction of 2-12 cells in 10% AC-2TM containing medium.

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Sripada, Aparna. "Application of e-TDR to achieve precise time synchronization and controlled asynchronization of remotely located signals." 2013. http://hdl.handle.net/2152/22848.

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Time Domain Reflectometer (TDR) measures the electrical length of a cable from the applied end to the location of an impedance change. An impedance change causes a portion of the applied signal to reflect back based on the value of its reflection coefficient. The time of flight (TOF) between the applied and reflected wave is computed and multiplied with previously determined signal propagation velocity to determine the location of the impedance change. We intentionally open terminate the output end of the cable which makes the reflection coefficient be maximum (=1) to measure its electrical le

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