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Journal articles on the topic 'TDCS/TMS'

Author: Grafiati

Published: 9 March 2023

Last updated: 31 July 2025

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1

Kochanowski, Brian, Karina Kageki-Bonnert, Elizabeth A. Pinkerton, Darin D. Dougherty, and Tina Chou. "A Review of Transcranial Magnetic Stimulation and Transcranial Direct Current Stimulation Combined with Medication and Psychotherapy for Depression." Harvard Review of Psychiatry 32, no. 3 (2024): 77–95. http://dx.doi.org/10.1097/hrp.0000000000000396.

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Learning Objectives After participating in this CME activity, the psychiatrist should be better able to: • Compare and contrast therapies used in combination with transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) for treating MDD. Background Noninvasive neuromodulation, such as transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), has emerged as a major area for treating major depressive disorder (MDD). This review has two primary aims: (1) to review the current literature on combining TMS and tDCS with other therap

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Carolina Mastari, Devina, Windy Mariane Virenia Wariki, Ansye Momole, Herlyani Khosama, Finny Warouw, and Junita Maja Pertiwi. "A Meta-Analysis of the Effectiveness of Transcranial Magnetic Stimulation and Transcranial Direct Current Stimulation as Therapy of Insomnia." Chronobiology in Medicine 5, no. 4 (2023): 178–89. http://dx.doi.org/10.33069/cim.2023.0027.

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Objective: Insomnia serves as the most common sleep disorder. Transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) are amongst most popular treatment for insomnia. This research aimed to determine the comparative effectiveness of TMS and tDCS as therapies for insomnia.Methods: PubMed/MEDLINE, ScienceDirect, Google Scholar, ResearchGate, Wiley Library Online, and Neurona were used to search for randomized controlled trials (RCTs) comparing TMS/tDCS with sham group in insomnia. Meta-analysis was done to determine the effectiveness of TMS and tDCS as a therap

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Hummel, F., and L. G. Cohen. "W15.1 TMS and tDCS." Clinical Neurophysiology 122 (June 2011): S49. http://dx.doi.org/10.1016/s1388-2457(11)60165-x.

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Begemann, Marieke J., Bodyl A. Brand, Branislava Ćurčić-Blake, André Aleman, and Iris E. Sommer. "Efficacy of non-invasive brain stimulation on cognitive functioning in brain disorders: a meta-analysis." Psychological Medicine 50, no. 15 (2020): 2465–86. http://dx.doi.org/10.1017/s0033291720003670.

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AbstractBackgroundCognition is commonly affected in brain disorders. Non-invasive brain stimulation (NIBS) may have procognitive effects, with high tolerability. This meta-analysis evaluates the efficacy of transcranial magnetic stimulation (TMS) and transcranial Direct Current Stimulation (tDCS) in improving cognition, in schizophrenia, depression, dementia, Parkinson's disease, stroke, traumatic brain injury, and multiple sclerosis.MethodsA PRISMA systematic search was conducted for randomized controlled trials. Hedges' g was used to quantify effect sizes (ES) for changes in cognition after

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Nissim, Nicole R., Paul J. Moberg, and Roy H. Hamilton. "Efficacy of Noninvasive Brain Stimulation (tDCS or TMS) Paired with Language Therapy in the Treatment of Primary Progressive Aphasia: An Exploratory Meta-Analysis." Brain Sciences 10, no. 9 (2020): 597. http://dx.doi.org/10.3390/brainsci10090597.

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Noninvasive brain stimulation techniques, such as transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS), paired with behavioral language therapy, have demonstrated the capacity to enhance language abilities in primary progressive aphasia (PPA), a debilitating degenerative neurological syndrome that leads to declines in communication abilities. The aim of this meta-analysis is to systematically evaluate the efficacy of tDCS and TMS in improving language outcomes in PPA, explore the magnitude of effects between stimulation modalities, and examine potential mo

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MU, Yihong. "A systematic review of transcranial magnetic and direct current stimulation application on the improvement of reading ability of developmental dyslexia." Theoretical and Natural Science 32, no. 1 (2024): 143–54. http://dx.doi.org/10.54254/2753-8818/32/20240818.

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Transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), two non-invasive brain stimulation techniques (NIBS), are modulatory tools to probe into a possible causal and interaction relationship between brain structure and function. Developmental dyslexia (DD) is a neurodevelopmental disorder, which is characterized by significant and persistent difficulty in learning and reading-related skills. Previous studies have shown that TMS and tDCS play an important role in reading ability and neurocognitive plasticity, such as visuospatial working memory, attention, s

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Wilkins, Erik W., Richard J. Young, Daniel Houston, et al. "Non-Dominant Hemisphere Excitability Is Unaffected during and after Transcranial Direct Current Stimulation of the Dominant Hemisphere." Brain Sciences 14, no. 7 (2024): 694. http://dx.doi.org/10.3390/brainsci14070694.

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Transcranial direct current stimulation (tDCS) increases primary motor cortex (M1) excitability and improves motor performance when applied unilaterally to the dominant hemisphere. However, the influence of tDCS on contralateral M1 excitability both during and after application has not been quantified. The purpose was to determine the influence of tDCS applied to the dominant M1 on the excitability of the contralateral non-dominant M1. This study employed a double-blind, randomized, SHAM-controlled, within-subject crossover experimental design. Eighteen young adults performed two experimental

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Dell’Osso, Bernardo, and A. Carlo Altamura. "Transcranial Brain Stimulation Techniques For Major Depression: Should We Extend TMS Lessons to tDCS?" Clinical Practice & Epidemiology in Mental Health 10, no. 1 (2014): 92–93. http://dx.doi.org/10.2174/1745017901410010092.

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Transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) are non-invasive brain stimulation techniques that, by means of magnetic fields and low intensity electrical current, respectively, aim to interefere with and modulate cortical excitability, at the level of dorsolateral prefrontal cortex, in patients with major depression and poor response to standard antidepressants. While the clinical efficacy of TMS in major depression has been extensively investigated over the last 10 years, tDCS has attracted research interest only in the last years, with fewer rand

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McCambridge, Alana B., James W. Stinear, and Winston D. Byblow. "A dissociation between propriospinal facilitation and inhibition after bilateral transcranial direct current stimulation." Journal of Neurophysiology 111, no. 11 (2014): 2187–95. http://dx.doi.org/10.1152/jn.00879.2013.

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Propriospinal premotoneurons (PN) are essential for accurate control of the upper limb. They receive bilateral input from premotor (PM) and primary motor (M1) cortices. In humans, excitability of PNs can be estimated from motor-evoked potentials (MEPs) by pairing a descending volley using transcranial magnetic stimulation (TMS) to summate with an ascending volley from peripheral nerve stimulation at the C3–C4 level of the spinal cord. Transcranial direct current stimulation (tDCS) alters excitability of cortical and subcortical areas. A recent study demonstrated that cathodal tDCS can suppress

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Bradnam, Lynley V., Cathy M. Stinear, and Winston D. Byblow. "Cathodal transcranial direct current stimulation suppresses ipsilateral projections to presumed propriospinal neurons of the proximal upper limb." Journal of Neurophysiology 105, no. 5 (2011): 2582–89. http://dx.doi.org/10.1152/jn.01084.2010.

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This study investigated whether cathodal transcranial direct current stimulation (c-tDCS) of left primary motor cortex (M1) modulates excitability of ipsilateral propriospinal premotoneurons (PNs) in healthy humans. Transcranial magnetic stimulation (TMS) of the right motor cortex was used to obtain motor evoked potentials (MEPs) from the left biceps brachii (BB) while participants maintained contraction of the left BB. To examine presumed PN excitability, left BB MEPs were compared with those conditioned by median nerve stimulation (MNS) at the left elbow. Interstimulus intervals between TMS

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Zamfirache, Florin, Cristina Dumitru, Deborah-Maria Trandafir, Andrei Bratu, and Beatrice Mihaela Radu. "A Review of Transcranial Electrical and Magnetic Stimulation Usefulness in Major Depression Disorder—Lessons from Animal Models and Patient Studies." Applied Sciences 15, no. 7 (2025): 4020. https://doi.org/10.3390/app15074020.

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Chronic depression causes long-term structural and functional brain damage, making new effective therapies for depressed patients essential. Up to 30% of patients with depression are resistant to treatment and experience adverse effects. Alternative therapies may help achieve remission when used separately or with traditional therapies. Transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (tMS) are helpful therapeutic interventions for major depression (MMD). tDCS and tMS are noninvasive techniques that modulate the excitability of different brain regions. It ha

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Lan, Yadi. "The Effectiveness of tDCS And TMS for Treatment of Depression." Highlights in Science, Engineering and Technology 102 (July 11, 2024): 394–400. https://doi.org/10.54097/7jm5w890.

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Depression is a prevalent mental disorder that can lead to negative emotional states and physical reactions, including pain, insomnia, cognitive disorder and even suicidal tendencies, which largely effect one’s daily life. With the increasing pressures of modern life, the incidence of depression has risen, highlighting the importance of effective treatment. While antidepressants are commonly used, they often come with side effects and may lose effectiveness over time, especially in cases of Treatment-Resistant Depression (TRD) and major depressive disorder (MDD). In order to find a more effici

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Bradnam, Lynley V., Cathy M. Stinear, Gwyn N. Lewis, and Winston D. Byblow. "Task-Dependent Modulation of Inputs to Proximal Upper Limb Following Transcranial Direct Current Stimulation of Primary Motor Cortex." Journal of Neurophysiology 103, no. 5 (2010): 2382–89. http://dx.doi.org/10.1152/jn.01046.2009.

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Cathodal transcranial DC stimulation (c-tDCS) suppresses excitability of primary motor cortex (M1) controlling contralateral hand muscles. This study assessed whether c-tDCS would have similar effects on ipsi- and contralateral M1 projections to a proximal upper limb muscle. Transcranial magnetic stimulation (TMS) of left M1 was used to elicit motor evoked potentials (MEPs) in the left and right infraspinatus (INF) muscle immediately before and after c-tDCS of left M1, and at 20 and 40 min, post-c-tDCS. TMS was delivered as participants preactivated each INF in isolation (left, right) or both

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Kidgell, Dawson J., Robin M. Daly, Kayleigh Young, et al. "Different Current Intensities of Anodal Transcranial Direct Current Stimulation Do Not Differentially Modulate Motor Cortex Plasticity." Neural Plasticity 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/603502.

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Transcranial direct current stimulation (tDCS) is a noninvasive technique that modulates the excitability of neurons within the motor cortex (M1). Although the aftereffects of anodal tDCS on modulating cortical excitability have been described, there is limited data describing the outcomes of different tDCS intensities on intracortical circuits. To further elucidate the mechanisms underlying the aftereffects of M1 excitability following anodal tDCS, we used transcranial magnetic stimulation (TMS) to examine the effect of different intensities on cortical excitability and short-interval intraco

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Dai, Wenjun, Yao Geng, Hao Liu, et al. "Preconditioning with Cathodal High-Definition Transcranial Direct Current Stimulation Sensitizes the Primary Motor Cortex to Subsequent Intermittent Theta Burst Stimulation." Neural Plasticity 2021 (October 21, 2021): 1–8. http://dx.doi.org/10.1155/2021/8966584.

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Noninvasive brain stimulation techniques such as transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) can induce long-term potentiation-like facilitation, but whether the combination of TMS and tDCS has additive effects is unclear. To address this issue, in this randomized crossover study, we investigated the effect of preconditioning with cathodal high-definition (HD) tDCS on intermittent theta burst stimulation- (iTBS-) induced plasticity in the left motor cortex. A total of 24 healthy volunteers received preconditioning with cathodal HD-tDCS or sham int

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Bergmann, Til Ole, Sergiu Groppa, Markus Seeger, Matthias Mölle, Lisa Marshall, and Hartwig Roman Siebner. "Acute Changes in Motor Cortical Excitability During Slow Oscillatory and Constant Anodal Transcranial Direct Current Stimulation." Journal of Neurophysiology 102, no. 4 (2009): 2303–11. http://dx.doi.org/10.1152/jn.00437.2009.

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Transcranial oscillatory current stimulation has recently emerged as a noninvasive technique that can interact with ongoing endogenous rhythms of the human brain. Yet, there is still little knowledge on how time-varied exogenous currents acutely modulate cortical excitability. In ten healthy individuals we used on-line single-pulse transcranial magnetic stimulation (TMS) to search for systematic shifts in corticospinal excitability during anodal sleeplike 0.8-Hz slow oscillatory transcranial direct current stimulation (so-tDCS). In separate sessions, we repeatedly applied 30-s trials (two bloc

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Biabani, Mana, Maryam Aminitehrani, Maryam Zoghi, Michael Farrell, Gary Egan, and Shapour Jaberzadeh. "The effects of transcranial direct current stimulation on short-interval intracortical inhibition and intracortical facilitation: a systematic review and meta-analysis." Reviews in the Neurosciences 29, no. 1 (2017): 99–114. http://dx.doi.org/10.1515/revneuro-2017-0023.

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Abstract Transcranial direct current stimulation (tDCS) is increasingly being used to affect the neurological conditions with deficient intracortical synaptic activities (i.e. Parkinson’s disease and epilepsy). In addition, it is suggested that the lasting effects of tDCS on corticospinal excitability (CSE) have intracortical origin. This systematic review and meta-analysis aimed to examine whether tDCS has any effect on intracortical circuits. Eleven electronic databases were searched for the studies investigating intracortical changes induced by anodal (a) and cathodal (c) tDCS, in healthy i

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Iannone, Aline, Antonio Pedro de Mello Cruz, Joaquim Pereira Brasil-Neto, and Raphael Boechat-Barros. "Transcranial magnetic stimulation and transcranial direct current stimulation appear to be safe neuromodulatory techniques useful in the treatment of anxiety disorders and other neuropsychiatric disorders." Arquivos de Neuro-Psiquiatria 74, no. 10 (2016): 829–35. http://dx.doi.org/10.1590/0004-282x20160115.

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ABSTRACT Transcranial magnetic stimulation (TMS) has recently been investigated as a possible adjuvant treatment for many neuropsychiatric disorders, and has already been approved for the treatment of drug-resistant depression in the United States and in Brazil, among other countries. Although its use in other neuropsychiatric disorders is still largely experimental, many physicians have been using it as an off-label add-on therapy for various disorders. More recently, another technique, transcranial direct current stimulation (tDCS), has also become available as a much cheaper and portable al

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Saran, Brijesh. "Exploring the frontiers of neurostimulation: The role of transcranial direct current stimulation in modern neuroscience." Santosh University Journal of Health Sciences 10, no. 2 (2024): 161–72. https://doi.org/10.4103/sujhs.sujhs_58_24.

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ABSTRACT Introduction: Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation technique that has gained significant interest in both clinical and research settings. It involves applying a low, constant electrical current to the scalp to modulate neuronal activity. tDCS is valued for its cost-effectiveness, portability, and simplicity compared to other brain stimulation methods such as transcranial magnetic stimulation (TMS). This article explores the historical context, mechanisms, and clinical applications of tDCS, highlighting its potential in treating neurological

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Tscherpel, Caroline, and Christian Grefkes. "Funktionserholung nach Schlaganfall und die therapeutische Rolle der nicht-invasiven Hirnstimulation." Klinische Neurophysiologie 51, no. 04 (2020): 214–23. http://dx.doi.org/10.1055/a-1272-9435.

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ZusammenfassungIm Bereich der non-invasiven Hirnstimulation stellen die transkranielle Magnetstimulation (engl. transcranial magnetic stimulation, TMS) sowie die transkranielle Gleichstromstimulation (engl. transcranial direct current stimulation, tDCS) bis heute die wichtigsten Techniken zur Modulation kortikaler Erregbarkeit dar. Beide Verfahren induzieren Nacheffekte, welche die Zeit der reinen Stimulation überdauern, und ebnen damit den Weg für ihren therapeutischen Einsatz beim Schlaganfall. In diesem Übersichtsartikel diskutieren wir die aktuelle Datenlage TMS- und tDCS-vermittelter Ther

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Wang, Yao, Wan Liu, Jiu Chen, et al. "Comparative efficacy of different noninvasive brain stimulation therapies for recovery of global cognitive function, attention, memory, and executive function after stroke: a network meta-analysis of randomized controlled trials." Therapeutic Advances in Chronic Disease 14 (January 2023): 204062232311687. http://dx.doi.org/10.1177/20406223231168754.

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Background: Which noninvasive brain stimulation (NIBS) treatment – transcranial direct current stimulation (tDCS) or transcranial magnetic stimulation (TMS) – is more beneficial for stroke patients’ cognitive rehabilitation is still up for debate. Objectives: Our goal is to provide an overview of the research on the effectiveness and safety of various NIBS protocols. Design: Systematic review and network meta-analysis (NMA) of randomized controlled trials (RCTs). Methods: This NMA compared any active NIBS versus sham stimulation in adult stroke survivors to enhance cognitive function, with a f

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Brunoni, André Russowsky, Chei Tung Teng, Claudio Correa, et al. "Neuromodulation approaches for the treatment of major depression: challenges and recommendations from a working group meeting." Arquivos de Neuro-Psiquiatria 68, no. 3 (2010): 433–51. http://dx.doi.org/10.1590/s0004-282x2010000300021.

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The use of neuromodulation as a treatment for major depressive disorder (MDD) has recently attracted renewed interest due to development of other non-pharmacological therapies besides electroconvulsive therapy (ECT) such as transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), deep brain stimulation (DBS), and vagus nerve stimulation (VNS). METHOD: We convened a working group of researchers to discuss the updates and key challenges of neuromodulation use for the treatment of MDD. RESULTS: The state-of-art of neuromodulation techniques was reviewed and discuss

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Galea, Joseph M., and Pablo Celnik. "Brain Polarization Enhances the Formation and Retention of Motor Memories." Journal of Neurophysiology 102, no. 1 (2009): 294–301. http://dx.doi.org/10.1152/jn.00184.2009.

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One of the first steps in the acquisition of a new motor skill is the formation of motor memories. Here we tested the capacity of transcranial DC stimulation (tDCS) applied over the motor cortex during motor practice to increase motor memory formation and retention. Nine healthy individuals underwent a crossover transcranial magnetic stimulation (TMS) study designed to test motor memory formation resulting from training. Anodal tDCS elicited an increase in the magnitude and duration of motor memories in a polarity-specific manner, as reflected by changes in the kinematic characteristics of TMS

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Gunduz, Muhammed Enes, Kevin Pacheco-Barrios, Camila Bonin Pinto, et al. "Effects of Combined and Alone Transcranial Motor Cortex Stimulation and Mirror Therapy in Phantom Limb Pain: A Randomized Factorial Trial." Neurorehabilitation and Neural Repair 35, no. 8 (2021): 704–16. http://dx.doi.org/10.1177/15459683211017509.

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Phantom limb pain (PLP) is a frequent complication in amputees, which is often refractory to treatments. We aim to assess in a factorial trial the effects of transcranial direct current stimulation (tDCS) and mirror therapy (MT) in patients with traumatic lower limb amputation; and whether the motor cortex plasticity changes drive these results. In this large randomized, blinded, 2-site, sham-controlled, 2 × 2 factorial trial, 112 participants with traumatic lower limb amputation were randomized into treatment groups. The interventions were active or covered MT for 4 weeks (20 sessions, 15 min

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Álvarez-Pérez, Yolanda, Andrea Duarte-Díaz, Amado Rivero-Santana, et al. "PD99 Effectiveness And Safety Of Bioelectrical Stimulation Techniques In Fibromyalgia: A Systematic Review." International Journal of Technology Assessment in Health Care 40, S1 (2024): S133. https://doi.org/10.1017/s0266462324003453.

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IntroductionFibromyalgia, a musculoskeletal ailment of unknown origin, profoundly affects quality of life. Emerging bioelectrical stimulation techniques, including transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), and pulsed low-frequency magnetic field stimulation (PEMF), show promise in short-term pain alleviation. This study aimed to rigorously evaluate the effectiveness and safety of these techniques in treating fibromyalgia.MethodsA systematic review (SR) of available literature on the effectiveness and safety of bioelectrical stimulation techniques

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Oliveira, Jefferson Borges de, Rafael Glória Zatta, Robson Lázaro, Tiago Zani, and Victor Edgar Pitzer Neto. "Neuromodulação em doenças neurodegenerativas: técnicas emergentes para Parkinson e esclerose múltipla." IOSR Journal of Business and Management 27, no. 6 (2025): 07–22. https://doi.org/10.9790/487x-2706110722.

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transcraniana (TMS) e neurofeedback são discutidos em termos de mecanismos de ação, eficácia clínica e limitações. Avanços em dispositivos implantáveis inteligentes, capazes de ajustar parâmetros de estimulação em tempo real com base em sinais neurais, são analisados, destacando sistemas adaptativos em Parkinson e propostas de ajuste dinâmico em esclerose múltipla. A revisão engloba evidências clínicas recentes, parâmetros de estimulação, seleção de pacientes e resultados sintomáticos (motor, cognitivo e qualidade de vida). Apesar de resultados promissores em estudos piloto e ensaios controlad

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Behrangrad, Shabnam, Maryam Zoghi, Dawson Kidgell, Farshad Mansouri, and Shapour Jaberzadeh. "The effects of concurrent bilateral anodal tDCS of primary motor cortex and cerebellum on corticospinal excitability: a randomized, double-blind sham-controlled study." Brain Structure and Function 227, no. 7 (2022): 2395–408. http://dx.doi.org/10.1007/s00429-022-02533-7.

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AbstractTranscranial direct current stimulation (tDCS) applied to the primary motor cortex (M1), and cerebellum (CB) can change the level of M1 corticospinal excitability (CSE). A randomized double-blinded crossover, the sham-controlled study design was used to investigate the effects of concurrent bilateral anodal tDCS of M1 and CB (concurrent bilateral a-tDCSM1+CB) on the CSE. Twenty-one healthy participants were recruited in this study. Each participant received anodal-tDCS (a-tDCS) of 2 mA, 20 min in four pseudo-randomized, counterbalanced sessions, separated by at least 7 days (7.11 days

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Keerthy, B. N., Sai Sreevalli Sarma Sreepada, Shalini S. Naik, et al. "Effects of a single session of cathodal transcranial direct current stimulation primed intermittent theta-burst stimulation on heart rate variability and cortical excitability measures." Indian Journal of Physiology and Pharmacology 65 (December 8, 2021): 162–66. http://dx.doi.org/10.25259/ijpp_339_2020.

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Objectives: Transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) have been used as neuromodulators in neuropsychiatric conditions. This study is aimed to find the effects of a single session of priming cathodal tDCS with intermittent theta-burst stimulation (iTBS) over left dorsolateral prefrontal cortex on heart rate variability (HRV) and cortical excitability parameters before and after perturbation. Materials and Methods: The neuromodulatory techniques used in the study were Cathodal tDCS for 20 min followed by iTBS for 3 min on the left dorsolateral pr

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Sabé, Michel, Joshua Hyde, Catharina Cramer, et al. "Transcranial Magnetic Stimulation and Transcranial Direct Current Stimulation Across Mental Disorders." JAMA Network Open 7, no. 5 (2024): e2412616. http://dx.doi.org/10.1001/jamanetworkopen.2024.12616.

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ImportanceNoninvasive brain stimulation (NIBS) interventions have been shown to be efficacious in several mental disorders, but the optimal dose stimulation parameters for each disorder are unknown.ObjectiveTo define NIBS dose stimulation parameters associated with the greatest efficacy in symptom improvement across mental disorders.Data SourcesStudies were drawn from an updated (to April 30, 2023) previous systematic review based on a search of PubMed, OVID, and Web of Knowledge.Study SelectionRandomized clinical trials were selected that tested transcranial magnetic stimulation (TMS) or tran

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Kesikburun, Serdar. "Non-invasive brain stimulation in rehabilitation." Turkish Journal of Physical Medicine and Rehabilitation 68, no. 1 (2022): 1–8. http://dx.doi.org/10.5606/tftrd.2022.10608.

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Non-invasive brain stimulation (NIBS) has been seen more common in rehabilitation settings. It can be used for the treatment of stroke, spinal cord injury, traumatic brain injury and multiple sclerosis, as well as for some diagnostic neurophysiological measurements. Two major modalities of NIBS are transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS). As an add-on therapy to conventional rehabilitative treatments, the main goal of NIBS is to create neuromodulation by inhibiting or activating neural activity in the targeted cortical region. Indications for

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Zaninotto, Ana Luiza, Mirret M. El-Hagrassy, Jordan R. Green, et al. "Transcranial direct current stimulation (tDCS) effects on traumatic brain injury (TBI) recovery: A systematic review." Dementia & Neuropsychologia 13, no. 2 (2019): 172–79. http://dx.doi.org/10.1590/1980-57642018dn13-020005.

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ABSTRACT. Traumatic brain injury (TBI) is a major cause of chronic disability. Less than a quarter of moderate and severe TBI patients improved in their cognition within 5 years. Non-invasive brain stimulation, including transcranial direct current stimulation (tDCS), may help neurorehabilitation by boosting adaptive neuroplasticity and reducing pathological sequelae following TBI. Methods: we searched MEDLINE/PubMed and Web of Science databases. We used Jadad scale to assess methodological assumptions. Results: the 14 papers included reported different study designs; 2 studies were open-label

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Caulfield, Kevin. "Toward prospective electric field dosing in TMS and tDCS." Brain Stimulation 14, no. 6 (2021): 1739. http://dx.doi.org/10.1016/j.brs.2021.10.502.

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Bailey, Neil W., Richard H. Thomson, Kate E. Hoy, Julio C. Hernandez-Pavon, and Paul B. Fitzgerald. "TDCS increases cortical excitability: Direct evidence from TMS-EEG." Cortex 74 (January 2016): 320–22. http://dx.doi.org/10.1016/j.cortex.2014.10.022.

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Mikkonen, M., and I. Laakso. "Inter-postural changes in TDCS and TMS electric fields." Brain Stimulation 12, no. 2 (2019): 497–98. http://dx.doi.org/10.1016/j.brs.2018.12.628.

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Romero Lauro, Leonor J., Mario Rosanova, Giulia Mattavelli, et al. "TDCS increases cortical excitability: Direct evidence from TMS–EEG." Cortex 58 (September 2014): 99–111. http://dx.doi.org/10.1016/j.cortex.2014.05.003.

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Ferrucci, Roberta, Tommaso Bocci, Francesca Cortese, Fabiana Ruggiero, and Alberto Priori. "Noninvasive Cerebellar Stimulation as a Complement Tool to Pharmacotherapy." Current Neuropharmacology 17, no. 1 (2018): 14–20. http://dx.doi.org/10.2174/1570159x15666171114142422.

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Background: Cerebellar ataxias represent a wide and heterogeneous group of diseases characterized by balance and coordination disturbance, dysarthria, dyssynergia and adyadococinesia, caused by a dysfunction in the cerebellum. In recent years there has been growing interest in discovering therapeutical strategy for specific forms of cerebellar ataxia. Together with pharmacological studies, there has been growing interest in non-invasive cerebellar stimulation techniques to improve ataxia and limb coordination. Both transcranial magnetic stimulation (TMS) and transcranial direct current stimula

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Vatrano, Martina, Idan Efim Nemirovsky, Paolo Tonin, and Francesco Riganello. "Assessing Consciousness through Neurofeedback and Neuromodulation: Possibilities and Challenges." Life 13, no. 8 (2023): 1675. http://dx.doi.org/10.3390/life13081675.

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Neurofeedback is a non-invasive therapeutic approach that has gained traction in recent years, showing promising results for various neurological and psychiatric conditions. It involves real-time monitoring of brain activity, allowing individuals to gain control over their own brainwaves and improve cognitive performance or alleviate symptoms. The use of electroencephalography (EEG), such as brain–computer interface (BCI), transcranial direct current stimulation (tDCS), and transcranial magnetic stimulation (TMS), has been instrumental in developing neurofeedback techniques. However, the appli

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Lapid, Maria I., Georgios Petrides, Adriana P. Hermida, and Brent P. Forester. "S2: Neuromodulation in Geriatric Psychiatry: Innovations and Insights in ECT, TMS, tDCS, and Cannabinoid Therapies." International Psychogeriatrics 36, S1 (2024): 9. http://dx.doi.org/10.1017/s1041610224001005.

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With the rapidly aging population worldwide, the psychiatric care of older adults faces increasingly complex challenges. Geriatric psychiatry must adapt to address the rising prevalence of depression, anxiety, and cognitive impairments with innovative and effective treatments. Neuromodulation in geriatrics encompasses a variety of innovative treatments designed to help manage symptoms of various neurological and psychiatric conditions common in older adults. This symposium will explore the mechanisms, clinical applications, safety, and up-to-date research in Electroconvulsive Therapy (ECT), Tr

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Nardone, Raffaele, Jürgen Bergmann, Monica Christova, et al. "Effect of Transcranial Brain Stimulation for the Treatment of Alzheimer Disease: A Review." International Journal of Alzheimer's Disease 2012 (2012): 1–5. http://dx.doi.org/10.1155/2012/687909.

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Available pharmacological treatments for Alzheimer disease (AD) have limited effectiveness, are expensive, and sometimes induce side effects. Therefore, alternative or complementary adjuvant therapeutic strategies have gained increasing attention. The development of novel noninvasive methods of brain stimulation has increased the interest in neuromodulatory techniques as potential therapeutic tool for cognitive rehabilitation in AD. In particular, repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) are noninvasive approaches that induce prolon

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Rapinesi, Chiara, Georgios D. Kotzalidis, Stefano Ferracuti, Gabriele Sani, Paolo Girardi, and Antonio Del Casale. "Brain Stimulation in Obsessive-Compulsive Disorder (OCD): A Systematic Review." Current Neuropharmacology 17, no. 8 (2019): 787–807. http://dx.doi.org/10.2174/1570159x17666190409142555.

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Background: Obsessive-compulsive disorder (OCD) is a highly prevalent, severe, and chronic disease. There is a need for alternative strategies for treatment-resistant OCD. Objective: This review aims to assess the effect of brain stimulation techniques in OCD. Methods: We included papers published in peer-reviewed journals dealing with brain stimulation techniques in OCD. We conducted treatment-specific searches for OCD (Technique AND ((randomized OR randomised) AND control* AND trial) AND (magnetic AND stimulation OR (rTMS OR dTMS)) AND (obsess* OR compuls* OR OCD)) on six databases, i.e., Pu

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Machado, Yuri de Castro, Mariana Oliveira, Mateus Pereira Mundoca, Bernardo Viana, Debora Marques de Miranda, and Marco Aurélio Romano-Silva. "Effects of non-invasive brain stimulation on impulsivity in patients with mental disorders: a systematic review and meta-analysis of randomised clinical trials." General Psychiatry 37, no. 6 (2024): e101220. https://doi.org/10.1136/gpsych-2023-101220.

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BackgroundNon-invasive brain stimulation (NIBS) techniques, such as transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), may offer an alternative treatment strategy for impulsive behaviour. By modulating brain activity, these techniques could potentially enhance impulse control and mitigate impulsivity.AimsTo provide a comprehensive analysis of the correlation between NIBS parameters, targeted brain regions and impulsivity.MethodsWe systematically searched PubMed, Scopus and Embase on 5 April 2023 for randomised controlled trials (RCTs) of NIBS on impulsi

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Knodel, N., S. Pillen, D. Hermle, M. Hanke, U. Ziemann, and T. O. Bergmann. "P18 TDCS intensity-dependent online modulation of motor cortex excitability: a combined TDCS-TMS study." Clinical Neurophysiology 130, no. 8 (2019): e154-e155. http://dx.doi.org/10.1016/j.clinph.2019.04.672.

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Pillen, S., N. Knodel, D. Hermle, M. Hanke, U. Ziemann, and T. Bergmann. "P144 TDCS intensity-dependent online modulation of motor cortex excitability: A combined TDCS-TMS study." Clinical Neurophysiology 131, no. 4 (2020): e94-e95. http://dx.doi.org/10.1016/j.clinph.2019.12.255.

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Vanneste, Sven, Berthold Langguth, and Dirk De Ridder. "Do tDCS and TMS influence tinnitus transiently via a direct cortical and indirect somatosensory modulating effect? A combined TMS-tDCS and TENS study." Brain Stimulation 4, no. 4 (2011): 242–52. http://dx.doi.org/10.1016/j.brs.2010.12.001.

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Winkelbeiner, Stephanie, Whitney Muscat, Andrea Joanlanne, et al. "S43. ASSESSING THE VARIABILITY OF RESPONSE TO NON-INVASIVE BRAIN STIMULATION IN PSYCHOSIS." Schizophrenia Bulletin 46, Supplement_1 (2020): S48—S49. http://dx.doi.org/10.1093/schbul/sbaa031.109.

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Abstract Background Non-invasive brain stimulation has been introduced as add-on treatment for psychotic symptoms, not least because transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) have a low risk profile. Yet, the initial excitement is wearing off and there is a lack of consistent evidence from randomized controlled trials (RCT) for the efficacy of brain stimulation. It is often claimed that this is because patients respond very differently to brain stimulation, with some benefiting much more than others. However, is there really strong evidence from

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Ghosh, Soumya, David Hathorn, Jennifer Eisenhauer, Jesse Dixon, and Ian D. Cooper. "Anodal Transcranial Direct Current Stimulation over the Vertex Enhances Leg Motor Cortex Excitability Bilaterally." Brain Sciences 9, no. 5 (2019): 98. http://dx.doi.org/10.3390/brainsci9050098.

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In many studies, anodal transcranial Direct Current Stimulation (tDCS) is applied near the vertex to simultaneously facilitate leg motor cortex (M1) of both hemispheres and enhance recovery of gait and balance in neurological disorders. However, its effect on the excitability of leg M1 in either hemisphere is not well known. In this double-blind sham-controlled study, corticospinal excitability changes induced in leg M1 of both hemispheres by anodal (2 mA for 20 minutes) or sham tDCS (for 20 min) over the vertex were evaluated. Peak amplitudes of Transcranial Magnetic Stimulation (TMS) induced

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Bolognini, Nadia, Luca Zigiotto, Maíra Izzadora Souza Carneiro, and Giuseppe Vallar. "“How Did I Make It?”: Uncertainty about Own Motor Performance after Inhibition of the Premotor Cortex." Journal of Cognitive Neuroscience 28, no. 7 (2016): 1052–61. http://dx.doi.org/10.1162/jocn_a_00950.

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Optimal motor performance requires the monitoring of sensorimotor input to ensure that the motor output matches current intentions. The brain is thought to be equipped with a “comparator” system, which monitors and detects the congruence between intended and actual movement; results of such a comparison can reach awareness. This study explored in healthy participants whether the cathodal transcranial direct current stimulation (tDCS) of the right premotor cortex (PM) and right posterior parietal cortex (PPC) can disrupt performance monitoring in a skilled motor task. Before and after tDCS, par

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Giuffre, Adrianna, Ephrem Zewdie, James Wrightson, et al. "Effects of tDCS and HD-tDCS Enhanced Motor Learning on Robotic TMS Motor Maps in Children." Brain Stimulation 14, no. 6 (2021): 1635–36. http://dx.doi.org/10.1016/j.brs.2021.10.153.

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Godeiro, Clecio, Carina França, Rafael Bernhart Carra, et al. "Use of non-invasive stimulation in movement disorders: a critical review." Arquivos de Neuro-Psiquiatria 79, no. 7 (2021): 630–46. http://dx.doi.org/10.1590/0004-282x-anp-2020-0381.

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Abstract Background: Noninvasive stimulation has been widely used in the past 30 years to study and treat a large number of neurological diseases, including movement disorders. Objective: In this critical review, we illustrate the rationale for use of these techniques in movement disorders and summarize the best medical evidence based on the main clinical trials performed to date. Methods: A nationally representative group of experts performed a comprehensive review of the literature in order to analyze the key clinical decision-making factors driving transcranial magnetic stimulation (TMS) an

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Palimeris, Stephania, Yekta Ansari, Anthony Remaud, et al. "Are Changes in Corticomotor Excitability Associated with Improved Arm Functional Performance Following a Tailored Strength Training Intervention in Chronic Stroke Survivors?" Brain Sciences 15, no. 7 (2025): 700. https://doi.org/10.3390/brainsci15070700.

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Background/Objectives: We showed that a tailored strengthening intervention based on the size of motor evoked potentials (MEPs) elicited by transcranial magnetic stimulation (TMS) in the affected hemisphere resulted in an improved affected arm function, regardless of stroke severity. Also, adding anodal transcranial direct stimulation (atDCS) during training did not alter the results as participants receiving real or sham stimulation showed similar gains. The goal of this study was to report on the changes in basic measures of corticomotor excitability in response to the intervention and to de

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