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Journal articles on the topic 'Technetium 99 sestamibi'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Merlino, James I., Ko Kichul, Anthony Minotti, and Christopher R. McHenry. "The False Negative Technetium-99m-Sestatnibi Scan in Patients with Primary Hyperparathyroidism: Correlation with Clinical Factors and Operative Findings." American Surgeon 69, no. 3 (2003): 225–30. http://dx.doi.org/10.1177/000313480306900309.

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False negative (FN) results limit the efficacy of technetium-99m-sestamibi scanning for parathyroid localization. We determined the incidence of FN results and attempted to correlate it with clinical and operative findings. One hundred forty-six patients underwent parathyroidectomy; 89 had primary hyperparathyroidism (76 single adenoma and 13 multiglandular disease) and underwent sestamibi scanning. The false negative rate was 22 per cent with an overall sensitivity of 77 per cent and a positive predictive value of 99 per cent. Patients with single adenomas were more likely to have a true posi

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2

Hung, Joseph C. "Paper chromatography procedure for testing the radiochemical purity of technetium-99 sestamibi." European Journal of Nuclear Medicine 23, no. 8 (1996): 1015–16. http://dx.doi.org/10.1007/bf01084384.

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Gremillet, Eric, and Andr� Champailler. "Comparative myocardial uptake of technetium-99 m sestamibi and technetium-99m tetrofosmin one hour after stress injection." European Journal of Nuclear Medicine and Molecular Imaging 25, no. 11 (1998): 1502–10. http://dx.doi.org/10.1007/s002590050328.

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4

Mohammadinia, Salam, Seyed M. Abedi, and Zohreh Noaparast. "St. John’s Wort accelerates the liver clearance of technetium-99-sestamibi in rats." Nuclear Medicine Communications 39, no. 9 (2018): 839–44. http://dx.doi.org/10.1097/mnm.0000000000000880.

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5

L, Yen Nee, Masni M, Azraai Bahari N, Nurain MN, and Zanariah H. "ECTOPIC PARATHYROID ADENOMA, A DIAGNOSTIC CHALLENGE." Journal of the ASEAN Federation of Endocrine Societies 34 (July 17, 2019): 52. https://doi.org/10.15605/jafes.034.s90.

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INTRODUCTIONPrimary hyperparathyroidism is the most common cause of hypercalcemia. Approximately 85% of primary hyperparathyroidism is caused by solitary parathyroid adenomas and 5-10% of cases derived from ectopic adenomas. Ectopic parathyroid glands remain a diagnostic and operative challenge in terms of localizing the culprit gland. CASEWe reported a case of primary hyperparathyroidism due to ectopic parathyroid adenoma in the thymus. This 31-yearold gentleman presented with renal calculi, confirmed primary hyperparathyroidism with hypercalcemia. However initial ultrasound and CT neck were

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Fathala, Ahmed. "Dual Parathyroid Pathology; A Common Failure of Technetium-99 Sestamibi Scan for Preoperative Parathyroid Adenoma Localization." Nuclear Medicine, Radiology & Radiation Therapy 2, no. 1 (2017): 1–3. http://dx.doi.org/10.24966/nmrr-7419/100006.

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7

Romero, Lina, Iraj Khalkhali, and Hernan I. Vargas. "The role of nuclear medicine in breast cancer detection: A focus on technetium-99 sestamibi scintimammography." Current Oncology Reports 5, no. 1 (2003): 58–62. http://dx.doi.org/10.1007/s11912-003-0087-6.

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8

Chakrabarty, Nivedita, Abhishek Mahajan, Sandip Basu, and Anil K. D’Cruz. "Imaging Recommendations for Diagnosis and Management of Primary Parathyroid Pathologies: A Comprehensive Review." Cancers 16, no. 14 (2024): 2593. http://dx.doi.org/10.3390/cancers16142593.

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Parathyroid pathologies are suspected based on the biochemical alterations and clinical manifestations, and the predominant roles of imaging in primary hyperparathyroidism are localisation of tumour within parathyroid glands, surgical planning, and to look for any ectopic parathyroid tissue in the setting of recurrent disease. This article provides a comprehensive review of embryology and anatomical variations of parathyroid glands and their clinical relevance, surgical anatomy of parathyroid glands, differentiation between multiglandular parathyroid disease, solitary adenoma, atypical parathy

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Yalon, T., M. Neymark, A. Rottenberg, et al. "The Added Value of Technetium-99 m Sestamibi Scan in Patients with Primary Hyperparathyroidism and Positive Ultrasound." World Journal of Surgery 45, no. 7 (2021): 2148–54. http://dx.doi.org/10.1007/s00268-021-06066-8.

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10

Kontos, Michael C., Kristin L. Schmidt, Christopher S. Nicholson, Joseph P. Ornato, Robert L. Jesse, and James L. Tatum. "Myocardial perfusion imaging with technetium-99m sestamibi in patients with cocaine-associated chest Pain." Annals of Emergency Medicine 33, no. 6 (1999): 639–45. http://dx.doi.org/10.1016/s0196-0644(99)80001-8.

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TOMA, D. "Influence of arm positioning on rest/stress technetium-99m labeled sestamibi tomographic myocardial perfusion imaging." Journal of Nuclear Cardiology 6, no. 2 (1999): 163–68. http://dx.doi.org/10.1016/s1071-3581(99)90076-4.

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12

YAO, S. "Role of LVH in increased left ventricular volume measured by technetium-99m sestamibi gated SPECT." Journal of Nuclear Cardiology 6, no. 1 (1999): S73. http://dx.doi.org/10.1016/s1071-3581(99)90404-x.

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13

Chimura, Misato, Tomohito Ohtani, Fusako Sera, et al. "Focal severe decrease in myocardial technetium-99 m sestamibi uptake indicates ventricular irreversibility in patients with dilated cardiomyopathy." Annals of Nuclear Medicine 35, no. 8 (2021): 881–88. http://dx.doi.org/10.1007/s12149-021-01625-4.

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14

Nicholson, Christopher S., Michael C. Kontos, James L. Tatum, Joseph P. Ornato, and Robert L. Jesse. "Technetium 99-m sestamibi imaging in the patient with cocaine associated chest pain; alternative to routine CCU admissions." Journal of the American College of Cardiology 27, no. 2 (1996): 382. http://dx.doi.org/10.1016/s0735-1097(96)82452-1.

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15

Wei, John P., and George J. Burke. "Analysis of savings in operative time for primary hyperparathyroidism using localization with technetium 99m sestamibi scan." American Journal of Surgery 170, no. 5 (1995): 488–91. http://dx.doi.org/10.1016/s0002-9610(99)80336-5.

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16

ELHENDY, A. "Dobutamine-atropine 99M technetium sestamibi SPECT imaging for prognostic stratification late after Q wave myocardial infarction." Journal of Nuclear Cardiology 6, no. 1 (1999): S85. http://dx.doi.org/10.1016/s1071-3581(99)90452-x.

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KONTOS, M., K. SCHMIDT, C. NICHOLSON, J. ORNATO, R. JESSE, and J. TATUM. "Myocardial Perfusion Imaging With Technetium-99m Sestamibi in Patients With Cocaine-associated Chest Pain☆, ☆☆, ★, ★★." Annals of Emergency Medicine 33, no. 6 (1999): 639–45. http://dx.doi.org/10.1016/s0196-0644(99)70192-7.

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18

LI, G. "Effects of hypoxic preconditioning on technetium-99m-sestamibi and thallium-201 extraction in cultured rat heart cells." Journal of Nuclear Cardiology 6, no. 1 (1999): S53. http://dx.doi.org/10.1016/s1071-3581(99)90324-0.

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19

SLAVU, Iulian, Cornelia NITIPIR, Cristina ORLOV-SLAVU, et al. "Intraoperative Post-parathyroidectomy Correlation of PTH Hormone Values with Preoperative Scintigraphy." Medicina Moderna - Modern Medicine 30, no. 2 (2023): 95–99. http://dx.doi.org/10.31689/rmm.2023.30.2.95.

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Preoperative parathyroid evaluation through nuclear medicine and intraoperative hormone monitoring has significantly increased the success of the surgical intervention. Material and method: Our study is descriptive, the database is retrospective but it is maintained prospectively. The preoperative protocol included single photon emission computed tomography (SPECT) with the use of technetium-99 sestamibi tracer. We preferred this approach as it allowed 3-D localization of the adenomas. PTH values were obtained from blood drawn from the ipsilateral jugular vein at the regular intervals of 5, 10

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Levine, M. G., C. C. McGill, R. R. Azar, et al. "Low dose dobutamine ECG gated SPECT myocardial perfusion imaging with Technetium 99-m sestamibi predicts myocardial viability: a prospective study." Journal of the American College of Cardiology 31 (1998): 44. http://dx.doi.org/10.1016/s0735-1097(98)80844-9.

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21

Levine, M. "Low Dose Dobutamine ECG Gated SPECT Myocardial Perfusion Imaging With Technetium 99-m Sestamibi Predicts Myocardial Viability: A Prospective Study." Journal of the American College of Cardiology 31, no. 2 (1998): 44A. http://dx.doi.org/10.1016/s0735-1097(97)83905-8.

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22

Mustafa, Anila. "Abstract #1048: Technetium 99 -Sestamibi Thyroid Scan as an Imaging Modality in the Differential Diagnosis and Managment of Amiodarone Induce Thyrotoxicosis." Endocrine Practice 21 (May 2015): 214–15. http://dx.doi.org/10.1016/s1530-891x(20)42353-5.

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23

Carsote, Mara, Mihaela Stanciu, Florina Ligia Popa, et al. "Pitfalls of DualTracer 99m-Technetium (Tc) Pertechnetate and Sestamibi Scintigraphy before Parathyroidectomy: Between Primary-Hyperparathyroidism-Associated Parathyroid Tumour and Ectopic Thyroid Tissue." Medicina 60, no. 1 (2023): 15. http://dx.doi.org/10.3390/medicina60010015.

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Diagnosis of primary hyperparathyroidism (PHP) is based on blood assessments in terms of synchronous high calcium and PTH (parathormone), but further management, particularly parathyroid surgery that provides the disease cure in 95–99% of cases, requires an adequate localisation of the parathyroid tumour/tumours as the originating source, with ultrasound and 99m-Technetium (99m-Tc) sestamibi scintigraphy being the most widely used. We aimed to introduce an adult female case diagnosed with PHP displaying unexpected intra-operatory findings (ectopic thyroid tissue) in relation to concordant pre-

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Cotoi, Laura, Daniela Amzar, Ioan Sporea, et al. "Shear Wave Elastography versus Strain Elastography in Diagnosing Parathyroid Adenomas." International Journal of Endocrinology 2020 (March 17, 2020): 1–11. http://dx.doi.org/10.1155/2020/3801902.

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Objectives. The aim of the study was to compare elastographic means in parathyroid adenomas, using shear wave elastography and strain elastography. Methods. This prospective study examined 20 consecutive patients diagnosed with primary hyperparathyroidism and parathyroid adenoma, confirmed by biochemical assay, technetium-99 sestamibi scintigraphy, and pathology report, after parathyroid surgery. All patients were examined on conventional 2B ultrasound, 2D shear wave elastography, and strain elastography. We determined using 2D shear wave elastography (SWE) the elasticity index (EI) in parathy

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Lin, Ching-Cheng, Hueisch-Jy Ding, Yu-Wen Chen, Jhi-Joung Wang, Shung-Tai Ho, and Albert Kao. "Usefulness of technetium-99 m sestamibi myocardial perfusion SPECT in detection of cardiovascular involvement in patients with systemic lupus erythematosus or systemic sclerosis." International Journal of Cardiology 92, no. 2-3 (2003): 157–61. http://dx.doi.org/10.1016/s0167-5273(03)00106-2.

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Bitencourt, Fernanda Gobbi, Guilherme Oliveira Petersen, and Cássia Virginia Garcia. "Development of a rapid HPLC method for quantification of the copper tetramibi tetraflourborate in a kit for preparation of Technetium 99 m Sestamibi Injection." Biomedical Chromatography 33, no. 7 (2019): e4490. http://dx.doi.org/10.1002/bmc.4490.

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Duncan, Brett H., Alan W. Ahlberg, Michael G. Levine, et al. "Comparison of electrocardiographic-gated technetium-99m sestamibi single-photon emission computed tomographic imaging and rest-redistribution thallium-201 in the prediction of myocardial viability." American Journal of Cardiology 85, no. 6 (2000): 680–84. http://dx.doi.org/10.1016/s0002-9149(99)00840-1.

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28

Weaver, Travis D., Mohamed K. M. Shakir, and Thanh D. Hoang. "Hyperparathyroidism-Jaw Tumor Syndrome." Case Reports in Oncology 14, no. 1 (2021): 29–33. http://dx.doi.org/10.1159/000510002.

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Primary hyperparathyroidism is a relatively common endocrine disorder, affecting 7 out of 1,000 adults. The median age at onset is the 6th decade of life. Our objective was to present a young patient with primary hyperparathyroidism who has a positive <i>CDC73</i> mutation. A 23-year-old woman was evaluated for hypercalcemia that was found after surgery for bilateral ovarian cyst removal. Her family history included multiple family members with nephrolithiasis. The physical examination revealed a well-appearing Caucasian woman with no palpable neck mass. The laboratory results show

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Mutlu, Vahit, Mahmut Arif Yuksek, Zafer Pekkolay, Zeynep Yegin, Ibrahim Halil Yildirim, and Omer Uslukaya. "Radiologist- and Surgeon-Performed Ultrasound (RSUS) Facilitates Minimally İnvasive Parathyroidectomy (MIP): Optimal Biochemical Parameters and Patient Outcomes." Journal of Clinical Medicine 14, no. 7 (2025): 2279. https://doi.org/10.3390/jcm14072279.

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Background/Objectives: The high success rate of minimally invasive parathyroidectomy (MIP) is dependent upon the correct preoperative localization of the solitary parathyroid adenoma (SPA). Various studies have focused on comparisons of radiologist-performed ultrasound (RUS) and surgeon-performed ultrasound (SUS) to increase the sensitivity rate of US. However, the efficiency of radiologist- and surgeon-performed ultrasound (RSUS) before MIP has not frequently been reported. We aimed to evaluate the efficiency of RSUS in clinical practice. Methods: In total, 122 patients (107 females, 15 males

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ALLAM, A. "Comparison of Stress-Reinjection Thallium scintigraphy and stress-rest technetium - 99m SestaMIBI scintigraphy with or without nitrates potentiation. In assessment of patients with previous myocardial infarction." Journal of Nuclear Cardiology 6, no. 1 (1999): S51. http://dx.doi.org/10.1016/s1071-3581(99)90317-3.

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Abdelmoneim, Sahar S., Mathieu Bernier, Abhijeet Dhoble, et al. "Diagnostic accuracy of contrast echocardiography during adenosine stress for detection of abnormal myocardial perfusion: a prospective comparison with technetium-99 m sestamibi single-photon emission computed tomography." Heart and Vessels 25, no. 2 (2010): 121–30. http://dx.doi.org/10.1007/s00380-009-1174-x.

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Obołończyk, Łukasz, Izabela Karwacka, Piotr Wiśniewski, Krzysztof Sworczak, and Tomasz Osęka. "The Current Role of Parathyroid Fine-Needle Biopsy (P-FNAB) with iPTH-Washout Concentration (iPTH-WC) in Primary Hyperparathyroidism: A Single Center Experience and Literature Review." Biomedicines 10, no. 1 (2022): 123. http://dx.doi.org/10.3390/biomedicines10010123.

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Introduction. Primary hyperparathyroidism (PHPT) is a condition characterized by disorders of calcium–phosphate metabolism and bone metabolism caused by pathological overproduction of parathyroid hormone (PTH). The diagnosis of overt PHPT is based on the presence of clinical symptoms and laboratory abnormalities typical of this condition: hypercalcemia, hypercalciuria and elevated iPTH levels. Imaging studies are not used for diagnostic purposes; they are performed to localize the parathyroid glands prior to potential surgical treatment. Technetium 99 m sestamibi scintigraphy (Tc99 m-MIBI) is

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Alex, Manuel, Nabil Badro Dr., and Al-Jehani Ahmed. "Case Report: Development of Leukocytoclastic Vasculitis after Cardiac Stress Test with Technetium 99 Sestamibi." June 27, 2017. https://doi.org/10.5281/zenodo.819741.

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<em>Leukocytoclastic vasculitis (LCV) is a small vessel vasculitis that presents most commonly as palpable purpura. In our case report we note a patient that develops LCV which progressed from purpura to painful necrotic ulcers after exposure to technetium 99 sestamibi. It has been hypothesized as a potential trigger but this case is the first to document it as such. We also propose that our patient’s extensive allergy history may have predisposed her to developing LCV. </em>

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Yang, Jun, Xili Lu, Pingping Zhou, et al. "Comparison of four-dimensional CT and Sestamibi SPECTCT in the localization management of primary hyperparathyroidism." Cancer Imaging 25, no. 1 (2025). https://doi.org/10.1186/s40644-025-00897-7.

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Abstract Objective Accurate preoperative imaging localization is paramount to the success of targeted parathyroidectomy for primary hyperparathyroidism (PHPT). Four-dimensional (4D) CT is a promising method for preoperative localization of the parathyroid, but studies on the performance of 4D CT and technetium 99 m-sestamibi SPECT/CT for the diagnosis of diseases of the parathyroid are limited. Materials and methods To compare the diagnostic performance of sestamibi SPECT/CT and 4D-CT for preoperative localization in patients with PHPT in a single-institution from August 2017 to May 2024. Resu

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Smayra, Karen, Shahid Miangul, Joseph Nasr, et al. "Diagnostic Accuracy of Four-Dimensional Computed Tomography in Preoperative Localization of Primary Hyperparathyroidism After Negative or Inconclusive Sestamibi: A Systematic Review and Meta-analysis." Journal of Computer Assisted Tomography, November 13, 2024. http://dx.doi.org/10.1097/rct.0000000000001689.

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Objective The aim of the study is to assess the diagnostic accuracy of 4-dimensional computed tomography (4D-CT) scans for patients with primary hyperparathyroidism (pHPT) after negative or inconclusive Technetium-99m sestamibi single-photon emission computed tomography scan. Methods A literature search of several databases was conducted from inception to August 2023. Eligible studies reported adult patients (>18 years old) who underwent 4D-CT after negative or inconclusive sestamibi results. The pooled proportions were analyzed using a random-effects model. This review was registered in PR

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Persaud, Christine K., Nicholas S. Thorneloe, Zachary K. Matthews, Rutger S. Gunther, and Darrick J. Beckman. "Dual-mediated PTH and Osteolytic Hypercalcemia in Metastatic Endometrial Carcinoma." JCEM Case Reports 3, no. 5 (2025). https://doi.org/10.1210/jcemcr/luaf060.

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Abstract Hypercalcemia of malignancy (HCM) occurs frequently in advanced stage cancer and can be secondary to many different etiologies. This case illustrates a rare case of dual-mediated PTH and osteolytic HCM in the setting of metastatic endometrial carcinoma. The patient's hypercalcemia was refractory to initial treatment with IV hydration, calcitonin, and zoledronic acid, eventually requiring the addition of denosumab therapy and cinacalcet. After 15 days of treatment, the patient's calcium concentration returned to normal levels. Owing to elevated PTH levels, other etiologies of hypercalc

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He, Yudi, Yanwen Luo, Siqi Jin, et al. "Can we skip technetium-99 m sestamibi scintigraphy in pediatric primary hyperparathyroidism patients with positive neck ultrasound results?" Pediatric Radiology, July 13, 2023. http://dx.doi.org/10.1007/s00247-023-05702-w.

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Abstract Background Parathyroidectomy is the only curative treatment for primary hyperparathyroidism (PHPT). Ultrasound (US) and technetium-99 m sestamibi (99mTc-MIBI) scintigraphy are recommended as the first-line localization imaging modalities for PHPT in adults, but the value of preoperative imaging in pediatric patients has not been reported. Objective To evaluate the added value of 99mTc-MIBI scintigraphy in pediatric PHPT patients with positive ultrasound results. Materials and methods Pediatric patients (≤18 years old) who were diagnosed with PHPT and underwent surgical treatment in Pe

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Warshavsky, Anton, Raz Rubin, Narin Nard Carmel‐Neidermann, et al. "4DCT in Discordant Parathyroid Adenoma Scans: Case Series and Meta‐Analysis." Laryngoscope, November 6, 2023. http://dx.doi.org/10.1002/lary.31142.

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ObjectiveTo evaluate the accuracy of four‐dimensional computerized‐tomography (4DCT) for localizing parathyroid adenomas (PTAs) in cases with discordant or non‐localizing ultrasonography (US) and Technetium‐99 sestamibi (MIBI) scans.Data SourcesRetrospective case series and systematic review.Review MethodsA case series and meta‐analysis of patients diagnosed with primary hyperparathyroidism and discordant US and MIBI scans who underwent 4DCT prior to surgery. A comprehensive search for all relevant publications in the English literature between December 2006 and March 2022 was conducted for th

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Supit, Nina ISH, Johanes Purwoto, Marlinda Adham, Fajar Lamhot Gultom, Callistus Bruce Henfry Sulay, and Gilbert Sterling Octavius. "The importance of multimodality imaging in diagnosing cystic parathyroid gland hyperplasia: a case report and systematic review." Egyptian Journal of Radiology and Nuclear Medicine 55, no. 1 (2024). http://dx.doi.org/10.1186/s43055-024-01380-2.

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Abstract Background Parathyroid cysts account for a small percentage of parathyroid lesions and are more prevalent in females. Cystic parathyroid hyperplasia is exceptionally rare, with only two cases reported thus far. This case report provides the readers with the first multimodality imaging in cystic parathyroid hyperplasia as well as the authors’ first experience in using a 4D computed tomography (CT) scan in our institution while the systematic review will comprehensively search and present similar cases. Main text The literature search started and ended on August 4, 2024. We searched fiv

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Abts, Trevor, Thinh Vu, Nancy D. Perrier, Yunyi Wang, Jing Ning, and J. Matthew Debnam. "Detection Rate and Concordance of 4D‐MDCT, US, and Tc99m MIBI Imaging in the Detection of Ectopic and Intrathyroidal Parathyroid Adenomas." World Journal of Surgery, February 23, 2025. https://doi.org/10.1002/wjs.12512.

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ABSTRACTBackgroundPrimary hyperparathyroidism is often caused by parathyroid adenomas (PAs), which can be ectopic (EPAs) or intrathyroidal (ITPAs). Accurate localization is crucial for effective surgical intervention. This study aimed to determine the detection rate of four‐dimensional multidetector computed tomography (4D‐MDCT), ultrasonography (US), and technetium 99 m sestamibi scintigraphy (MIBI) in detecting EPAs and ITPAs. Additionally, we explored the role of ultrasound‐guided fine‐needle aspiration (US‐FNA) and evaluated correlations between parathyroid hormone (PTH) levels, adenoma si

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Dwivedi, Girish, Rajesh Janardhanan, Sajad A. Hayat, Jonathan A. Swinburn, and Roxy Senior. "Abstract 2481: Myocardial Viability Determined by Myocardial Contrast Echocardiography is Superior to 99m Technetium Sestamibi Single Photon Emission Computed Tomography in Predicting Hard Cardiac Events Following Acute Myocardial Infarction." Circulation 116, suppl_16 (2007). http://dx.doi.org/10.1161/circ.116.suppl_16.ii_546-b.

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Introduction: The extent of residual myocardial viability (MV) following acute myocardial infarction (AMI) is an important determinant of outcome. 99m technetium sestamibi single photon emission computed tomography (SPECT) is widely used to assess MV following AMI. Hypothesis: We hypothesised that myocardial contrast echocardiography (MCE) which has a better spatial and temporal resolution compared to SPECT will be superior for predicting outcome following AMI. Methods: Accordingly, 99 patients who underwent simultaneous resting low-power MCE & nitrate enhanced SPECT 7 days after AMI were

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Cicek, Mehmet Turan, Mehmet Aslan, and Cigdem Firat Koca. "The effect of peroperative ultrasound used by the surgeon in parathyroidectomy on operation time." European Archives of Oto-Rhino-Laryngology, March 21, 2025. https://doi.org/10.1007/s00405-025-09319-7.

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Abstract Purpose One of the endocrine conditions that endocrinologists see the most frequently is primary hyperparathyroidism, which is brought on by a parathyroid adenoma. Minimally invasive parathyroidectomy (MIP) has become the first line of treatment for primary hyperparathyroidism due to solitary parathyroid adenoma. Surgeon-performed ultrasonography (SUS), which has been found to be extremely accurate in localizing aberrant glands, has been employed preoperatively to augment the sensitivity of high-resolution ultrasonography (hUS). Methods Two groups were randomly created from cases that

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Saboe, Aninka, Ferdy Sanjaya, Raden Erwin Affandi Soeriadi, et al. "Multiple pericardial hematomas: a case report and mini-review in multimodality imaging." BMC Medical Imaging 21, no. 1 (2021). http://dx.doi.org/10.1186/s12880-021-00617-0.

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Abstract Background Pericardial hematoma is blood accumulation in the pericardial space. Although rare, it could arise in various conditions, such as after cardiac surgery. Clinical diagnosis of pericardial hematoma is implausible; thus, cardiac imaging plays a pivotal role in identifying this condition. We presented a case of multiple pericardial hematomas, which was found as an incidental finding in post-cardiac surgery evaluation. We highlighted the diagnostic challenge and the key features of multi-modality cardiac imaging in pericardial hematoma evaluation. Case presentation An asymptomat

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Redfors, Björn, Reza Mohebi, Gennaro Giustino, et al. "Time Delay, Infarct Size, and Microvascular Obstruction After Primary Percutaneous Coronary Intervention for ST-Segment–Elevation Myocardial Infarction." Circulation: Cardiovascular Interventions 14, no. 2 (2021). http://dx.doi.org/10.1161/circinterventions.120.009879.

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Background: Symptom-to-balloon time (SBT) and door-to-balloon time (DBT) are both considered important metrics in patients undergoing primary percutaneous coronary intervention (pPCI) for ST-segment–elevation myocardial infarction (STEMI). We sought to assess the relationship of SBT and DBT with infarct size and microvascular obstruction (MVO) after pPCI. Methods: Individual patient data for 3115 ST-segment–elevation myocardial infarction patients undergoing pPCI in 10 randomized trials were pooled. Infarct size (% left ventricular mass) was assessed within 1 month after randomization by techn

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Akgün, Ismail Ethem, Mehmet Taner Ünlü, Nurcihan Aygun, Mehmet Kostek, and Mehmet Uludag. "Contribution of intraoperative parathyroid hormone monitoring to the surgical success in minimal invasive parathyroidectomy." Frontiers in Surgery 9 (September 21, 2022). http://dx.doi.org/10.3389/fsurg.2022.1024350.

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BackgroundThe contribution of intraoperative parathyroid hormone monitoring to minimally invasive parathyroidectomy remains controversial. We aimed to evaluate whether intraoperative parathyroid hormone monitoring monitoring could contribute to minimally invasive parathyroidectomy in these patients.MethodsThe data of the patients whose preoperative ultrasonography and technetium-99 m sestamibi scintigraphy imagings were positive and concordant for one gland and who underwent minimally invasive parathyroidectomy between 2003 and 2018 in our clinic, were evaluated retrospectively. Blood samples

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Medrano, Francisco. "Parathyroid Adenoma: Diverse Modalities of Clinical Presentation. Series of Cases and Literature Review. January 2010-October 2020." Open Access Journal of Endocrinology 5, no. 1 (2021). http://dx.doi.org/10.23880/oaje-16000158.

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The surgical treatment of Parathyroid Disease (PD) has change in the past two decades. The Parathyroid Adenoma (PA) represents 80%, some with symptoms others asymptomatic. The technological development of imaging methods has allowed greater precision in planning the surgical approach. The goal of parathyroidectomy is to cure. There are several surgical approaches from open cervical to minimal endoscopic surgery. Objective: The main of this study is to present the clinical characteristic, the diagnosis methods: biochemical and imaging, surgical approached and follow up. Methods: Descriptive stu

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Weaver, Travis, and Thanh Hoang. "SAT-334 A Genetic Cause of Primary Hyperparathyroidism." Journal of the Endocrine Society 4, Supplement_1 (2020). http://dx.doi.org/10.1210/jendso/bvaa046.225.

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Abstract Background: Primary hyperparathyroidism is a relatively common endocrine condition, affecting up to 7 out of every 1000 adults. Median age of onset is during the sixth decade of life. When present in younger patients primary hyperparathyroidism may indicate an underlying genetic cause. Case: A 23-year-old woman is referred for evaluation of hypercalcemia that was found on labs drawn after surgery for bilateral ovarian cyst removal. At the time of presentation she felt well and was without complaint. Her medical history is otherwise unremarkable. Her family history includes multiple fa

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Ruiz, Vanessa Goyes, and Nidhi Bansal. "SAT-341 Hyperparathyroid Crisis Precipitated by Rapid Correction of Symptomatic Hypercalcemia in an Occult Ectopic Parathyroid Adenoma." Journal of the Endocrine Society 4, Supplement_1 (2020). http://dx.doi.org/10.1210/jendso/bvaa046.803.

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Abstract Background: Parathyroid adenomas (PA) are typically benign, slow-growing tumors causing gradual increase in parathyroid hormone (PTH) and serum calcium (s.Ca) levels. Hyperparathyroid crisis is a rare and potentially fatal syndrome, which occurs due to rapid elevation of PTH and s.Ca levels (s.Ca &gt;15mg/dL). This can potentiate severe metabolic derangements, manifesting as altered mental status (AMS), renal insufficiency and cardiac arrhythmias. We present a case of hyperparathyroid crisis in the setting of an occult ectopic parathyroid adenoma. Case: 75 year old female with a m

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Chuki, Elias, Mark Raffeld, Joanna Klubo-Gwiezdzinska, Sriram Gubbi, and Smita Jha. "SAT556 An Unusual Case of Papillary Thyroid Carcinoma With Biallelic MEN1 Variants In a Patient With MEN1." Journal of the Endocrine Society 7, Supplement_1 (2023). http://dx.doi.org/10.1210/jendso/bvad114.2027.

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Abstract Disclosure: E. Chuki: None. M. Raffeld: None. J. Klubo-Gwiezdzinska: None. S. Gubbi: None. S. Jha: None. Introduction: Multiple endocrine neoplasia (MEN1) syndrome is caused by germline variants in MEN1. Papillary Thyroid Cancer (PTC) is not regarded as a canonical MEN1-related endocrine tumor. Pathogenic variants in MEN1 are rare in PTC. Herein, we report an MEN1 patient with biallelic loss of MEN1 in PTC.Clinical case: A 59-year-old Hispanic female presented with asymptomatic hypercalcemia due to primary hyperparathyroidism [serum calcium: 13.9 mg/dl (8.4-10.2), PTH: 314 pg/ml (15-6

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